Many people don’t know that they have abnormal blood lipids, including higher levels of LDL or overall cholesterol. That’s because there are usually no signs or symptoms associated with an early buildup of fatty plaques in the arteries.
Plaque is made up of cholesterol and fatty substances. It’s not until there may be a large blockage of the artery that you might notice something is wrong. For example, you may have chest pain, pain in the arms or jaw, nausea, sweating, shortness of breath, or weakness. These usually occur when the blood supply to the heart or brain is being slowed or blocked.
Unfortunately, these blockages can rupture and cause major problems, even when they are much smaller and don't yet cause any early symptoms. That is why, for some people, the first sign of elevated cholesterol may be a heart attack or stroke.
So – even if you’re feeling fine – regular cholesterol and blood lipid checks are important. Your blood lipids are considered in addition to other factors known to make heart disease or stroke more likely such as age, family history, if you have diabetes or high blood pressure, or if you smoke.
Blood Lipid Issues, High Cholesterol Can Run in Families
Famililal HypercholesterolemiaSome people are born with a condition called
familial hypercholesterolemia, or FH, leaving them with dangerously high levels of LDL or the “bad” type of cholesterol.
Such high levels of LDL cholesterol in the blood from such a young age puts people with FH at very high risk of
heart disease,
having a
heart attack or
stroke, or dying in the prime of their lives – often with no warning.
FH is passed down in families. For more information about FH, visit
CardioSmart.org/FH.
High Lipoprotein(a)Like LDL-cholesterol, high Lp(a) can cause narrowing of the arteries and damage heart valves. All adults should be tested at least once. Repeat testing is not usually needed because Lp(a) is mostly genetically determined and lifestyle changes don’t affect it. Elevated Lp(a) levels is among the most common inherited cholesterol disorder.
A high Lp(a) – greater than 125 nmol/L (or 50 mg/dL) – is linked to about a 40% higher long-term risk of heart attack or stroke. An Lp(a) of 250 nmol/L is associated with a doubling of the risk.
About 1 in 3 people with FH also have high
Lipoprotein(a), or Lp(a).