What are the signs and symptoms? For many people with familial hypercholesterolemia (FH), a heart attack, stroke or dying suddenly and at a young age may be the first sign.
Other possible signs may include:
- Angina, or chest pain or discomfort due to cholesterol buildup in the heart’s arteries
- Peripheral vascular disease, which is when cholesterol builds up in arteries in the legs, which may result in pain upon walking that usually subsides when resting
- Bumps on your tendons (called xanthomas), around your eyes (called xanthelasma) or on the tops of your hands
- White ring around the upper and lower portions of the cornea in the eye, especially before age 45
- Carotid artery disease, which is a narrowing of the blood vessels in the neck that carry blood from the heart to the brain