High Blood Pressure

Clinical Trial Finder

Many patients with high blood pressure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Preliminary Trial of Safety and Reducing Blood Pressure of Formula Salt With Limited Sodium Named ManLiKang in Hypertension Patients.

Conditions:   Hypertension;   Formula Salt With Limited Sodium
Intervention:   Dietary Supplement: formula salt with limited sodium named ManLiKang
Sponsor:   Peking University
Not yet recruiting - verified July 2017

Mechanisms of Refractory Hypertension (Reserpine)

Condition:   Refractory Hypertension
Intervention:   Drug: Reserpine
Sponsor:   University of Alabama at Birmingham
Recruiting - verified July 2017

S-amlodipine+Chlorthalidone vs S-amlodipine+Telmisartan in Hypertension

Condition:   Essential Hypertension
Interventions:   Drug: S-amlodipine 2.5mg + Chlorthalidone 25mg;   Drug: S-amlodipine 2.5mg + Telmisartan 40mg
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified July 2017

A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study

Condition:   Open-angle Glaucoma, Ocular Hypertension
Interventions:   Drug: Vehicle of DE-126 Ophthalmic Solution, high dose of DE-126 Ophthalmic Solution;   Drug: Topical ultra-low dose of DE-126 Ophthalmic Solution;   Drug: Topical low dose of DE-126 Ophthalmic Solution;   Drug: Topical medium dose of DE-126 Ophthalmic Solution;   Drug: Topical high dose of DE-126 Ophthalmic Solution;   Drug: 0.005% Latanoprost Ophthalmic Solution
Sponsor:   Santen Inc.
Not yet recruiting - verified July 2017

Self-management of Blood Pressure Medication for Hypertensive Veterans

Condition:   Hypertension
Intervention:   Other: self-management protocol for hypertension care
Sponsor:   VA Office of Research and Development
Not yet recruiting - verified July 2017

RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2

Conditions:   Cardiovascular Disease;   Hypertension
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified July 14, 2017

Chongqing Primary Aldosteronism Study

Condition:   Primary Aldosteronism
Intervention:   Other: no intervention
Sponsor:   Chongqing Medical University
Recruiting - verified July 2017

Isometric Training on Blood Pressure and on the Autonomic Modulation of Hypertensive Patients

Condition:   Hypertension
Intervention:   Behavioral: Intervention Group
Sponsor:   Hospital Israelita Albert Einstein
Not yet recruiting - verified July 2017

Effect of the Intra-abdominal Pressure on the Risk of Delirium in Mechanically Ventilated Patients.

Conditions:   Delirium;   Intraabdominal Hypertension;   Mechanical Ventilation Complication
Intervention:  
Sponsor:   Assiut University
Recruiting - verified July 2017

Certain Maternal Antibodies in Relation to Doppler in Hypertension With Pregnancy

Condition:   Pre-Eclampsia
Interventions:   Diagnostic Test: Doppler;   Diagnostic Test: serum antibodies
Sponsor:   Cairo University
Not yet recruiting - verified July 2017

Fimasartan on Hypertensive Cardiac Disease With Left Ventricular Hypertrophy Estimated by ECG

Conditions:   Left Ventricular Hypertrophy;   Hypertension
Intervention:   Drug: Fimasartan
Sponsor:   Seoul National University Bundang Hospital
Completed - verified July 2017

Integrated Computational modelIng of Right Heart Mechanics and Blood Flow Dynamics in Congenital Heart Disease

Conditions:   Congenital Heart Disease;   Pulmonary Hypertension
Interventions:   Procedure: Cardiac Magnetic Resonance - MRI;   Other: Cardiopulmonary Exercise Test;   Other: Blood Sampling for all participants
Sponsors:   National Heart Centre Singapore;   Ministry of Health, Singapore
Recruiting - verified July 2017

Kidney Injury Biomarkers in Preeclampsia

Condition:   Hypertension, Pregnancy-Induced
Intervention:   Diagnostic Test: Elisa assay of podocyte glycoprotein in urine
Sponsors:   Woman's Health University Hospital, Egypt;   Luxor International Hospital
Not yet recruiting - verified July 2017

Stress Management to Support Women's Health

Conditions:   Hypertension;   Stress;   Cardiovascular Diseases
Interventions:   Behavioral: MBCT-T;   Behavioral: Usual Care
Sponsor:   New York University School of Medicine
Not yet recruiting - verified July 2017

Antihypertensive Effect of Different Doses of Rostafuroxin in Comparison With Losartan

Condition:   Hypertension
Interventions:   Drug: Rostafuroxin;   Drug: Losartan
Sponsor:   Cvie Therapeutics Ltd.
Recruiting - verified July 2017

Serum Cobalt Status During Pregnancy and the Risks of PIH

Condition:   Cobalt Deficiency Disease
Intervention:  
Sponsor:   Anhui Medical University
Completed - verified July 2017

Ketamine v. Metoclopramide/Diphenhydramine for Acute Management of Migraine in the Emergency Department

Condition:   Migraine
Interventions:   Drug: Intranasal ketamine;   Drug: Diphenhydramine;   Drug: metoclopramide;   Drug: Normal saline
Sponsor:   The Brooklyn Hospital Center
Recruiting - verified July 2017

Effects of Pilates Method and Aerobic Training in Hypertensive Subjects

Condition:   Hypertension
Interventions:   Other: Aerobic Exercise;   Other: Pilates
Sponsor:   Universidade Federal de Santa Maria
Not yet recruiting - verified July 2017

Non-invasive Absolute Intracranial Pressure Measurement in Patients With Malignant Middle Cerebral Artery Infarction for Determination of Timing to Descompressive Craniectomy.

Condition:   Intracranial Pressure Increase
Intervention:   Device: Medical Device Vittamed 205
Sponsors:   Kienzler Jenny;   Schweizer National Fond
Not yet recruiting - verified July 2017

Prospective Urban Rural Epidemiology Study

Conditions:   Cardiovascular Diseases;   Risk Factor, Cardiovascular;   Health Behavior;   Environmental Exposure;   Lung Diseases;   Cancer;   Injuries;   Renal Disease;   Communicable Disease
Intervention:  
Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research (CIHR);   Heart and Stroke Foundation of Ontario
Recruiting - verified July 2017

Effectiveness and Tolerability of Long-Acting Nifedipine Gastrointestinal Therapeutic System in Chronic Kidney Disease With Uncontrolled Hypertension Patients, a Prospective, Multicenter, Observational Study

Condition:   Hypertension
Intervention:   Drug: Nifedipine controlled-release tablets (Adalat, BAYA1040)
Sponsor:   Bayer
Recruiting - verified July 2017

Comparison of the Medication Adherence of Patients Treated With Telmisartan/Hydrochlorothiazide or Telmisartan/Amlodipine Fixed Dose Combination (FDC) Versus Double-pill Combination Therapy in Real-world Japanese Therapeutic Practice

Condition:   Hypertension
Interventions:   Drug: subjects treated with telmisartan/hydrochlorothiazide;   Drug: Subjects treated with Telmisartan and amlodipine;   Drug: subjects treated with Telmisartan+hydrochlorothiazide double-pill combination group;   Drug: subjects treated with telmisartan+amlodipine double pill
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified July 2017

Fit After Baby: A Health Intervention to Increase Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease

Conditions:   Cardiovascular Diseases;   Diabetes;   Gestational Diabetes;   Preeclampsia;   Gestational Hypertension;   Small for Gestational Age at Delivery;   Preterm Birth;   Overweight and Obesity
Interventions:   Behavioral: Fit After Baby;   Behavioral: Text4Baby Control Group
Sponsor:   University of Colorado, Denver
Not yet recruiting - verified July 2017

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

Conditions:   Pheochromocytoma;   Paraganglioma
Interventions:   Drug: Lu-177-DOTATATE;   Drug: Ga-68-DOTATATE;   Other: F-18-FDG;   Drug: Amino Acid
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified April 13, 2017

Non-invasive Versus Invasive Blood Pressure Measurement in the Super Morbidly Obese Parturient With Severe Preeclampsia

Conditions:   Pre-Eclampsia;   Morbid Obesity;   Parturient;   Blood Pressure
Interventions:   Device: Non-invasive BP recording with conical Ultracheck Curve BP cuff;   Device: Non-invasive BP recording with traditional cylindrical BP cuff;   Other: Direct invasive arterial pressure
Sponsor:   Vanderbilt University Medical Center
Recruiting - verified July 2017

How do Super Lean Subjects Keep Resistant to Body Weight Gain?

Conditions:   Thinness;   Health Behavior;   Genetics
Intervention:   Behavioral: Superlean
Sponsor:   Chinese Academy of Medical Sciences
Recruiting - verified July 2017

DASH Cloud: Using Digital Health to Improve Adherence to the DASH Diet Among Women

Conditions:   Diet Modification;   Hypertension;   Women's Health;   Cardiovascular Diseases;   Digital Health
Interventions:   Other: DASH Cloud;   Other: Nutritionix Track app
Sponsor:   Duke University
Not yet recruiting - verified July 2017

Positive Psychology Intervention for Spanish-speaking Hispanic/Latino Adults at Risk for Cardiovascular Disease

Conditions:   Uncontrolled Hypertension;   Cardiovascular Risk Factor
Intervention:   Behavioral: Positive Psychological Intervention
Sponsors:   University of Illinois at Urbana-Champaign;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified June 2017

The Jiaxing Birth Cohort in China

Conditions:   Childhood Obesity;   Anemia;   Pregnancy Complications;   Pregnancy; Hypertension;   Feeding Behavior
Intervention:   Other: No intervention
Sponsors:   Zhejiang University;   Jiaxing Maternity and Child Health Care Hospital
Recruiting - verified June 2017

Efficacy and Necessity of Time Interval Between Instillation of Two Glaucoma Eye Drops

Conditions:   Glaucoma;   Glaucoma; Drugs
Interventions:   Behavioral: 5 minute interval between regular glaucoma drops - Long term;   Behavioral: no interval between regular glaucoma drops - Long term;   Drug: IOP reduction of Brimonidine and Timolol with time interval;   Drug: IOP reduction of Brimonidine and Timolol no time interval
Sponsor:   Sheba Medical Center
Not yet recruiting - verified June 2017

A Dose-escalation Study in Subjects With Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: GSK2586881
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified July 2017

Utility of EUS-elastography to Predict Portal Hypertension

Condition:   Portal Hypertension
Intervention:   Procedure: EUS-E to measure liver and spleen stiffness.
Sponsor:   Instituto Ecuatoriano de Enfermedades Digestivas
Recruiting - verified July 2017

Cardiac Rehabilitation in Patients With Refractory Angina

Condition:   Refractory Angina
Intervention:   Behavioral: Cardiac Rehabilitation
Sponsors:   Hospital Israelita Albert Einstein;   Fundação de Amparo à Pesquisa do Estado de São Paulo;   Instituto do Coracao
Recruiting - verified January 2017

Angiogenic Imaging in Pulmonary Arterial Hypertension

Conditions:   Pulmonary Arterial Hypertension;   Exercise Associated Pulmonary Arterial Hypertension
Intervention:   Diagnostic Test: PET-CT Imaging with [89Zr]-bevacizumab
Sponsors:   Brigham and Women's Hospital;   Boston Biomedical Innovation Center
Not yet recruiting - verified July 2017

Validation of a Physiological Based Pharmacokinetic Model by the Study of Paracetamol Distribution in the Brain Compartments in Brain Injured Patients

Condition:   Brain Injured Patients
Intervention:   Drug: Paracetamol
Sponsor:   Poitiers University Hospital
Recruiting - verified May 2017

Validity of 1BPM for Diagnosis of Hypertension

Condition:   Hypertension
Interventions:   Diagnostic Test: 1-hour blood pressure monitoring (1BPM);   Diagnostic Test: 24-hour ambulatory blood pressure monitoring (ABPM);   Diagnostic Test: Office blood pressure measurement (OBPM);   Diagnostic Test: Home blood pressure monitoring (HBPM)
Sponsors:   Consorci d'Atenció Primària de Salut de l'Eixample;   Instituto de Salud Carlos III
Recruiting - verified July 2017

Right Heart Catheterization Using Magnetic Resonance Imaging Fluoroscopy and Passive Guidewires

Conditions:   Pulmonary Artery Hypertension;   Congenital Heart Disease
Intervention:   Procedure: MRI Right Heart guidewire catheterization
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 30, 2017

Primary Aldosteronism In Hypertensive Patients in China

Conditions:   Hyperaldosteronism; Primary;   Hypertension Secondary
Interventions:   Diagnostic Test: Aldosterone/renin ratio (ARR) testing;   Diagnostic Test: Confirmatory tests
Sponsors:   Qifu Li;   Fu Wai Hospital, Beijing, China
Recruiting - verified July 2017

Glaucoma Management Optimism for African Americans Living With Glaucoma

Condition:   Glaucoma
Intervention:   Behavioral: Usual Care + Health Promotion Intervention
Sponsor:   University of Alabama at Birmingham
Not yet recruiting - verified July 2017

Carbetocin vs. Oxytocin at Elective Cesarean Section

Condition:   Postpartum Hemorrhage
Interventions:   Drug: Carbetocin;   Drug: Oxytocin
Sponsor:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting - verified July 2017

Prevalence of Liver Fibrosis and Cirrhosis in Patients With Squamous Cell Carcinoma of the Head and Neck

Conditions:   Liver Fibroses;   Liver Cirrhoses;   Squamous Cell Carcinoma of the Head and Neck
Intervention:   Other: Evaluation of the hepatic fibrosis stage by a hepatological assessment (Clinical, biological and imaging)
Sponsor:   Centre Hospitalier Universitaire, Amiens
Not yet recruiting - verified July 2017

Clinical Trial to Compare the Safety and Pharmacokinetics of YHP1604 in Comparison to the Co-administration of Telmisartan/Amlodipine and Rosuvastatin

Conditions:   Hypertension;   Hyperlipidemia
Interventions:   Drug: Temisartan/Amlodipine+Rosuvastatin;   Drug: YHP1604
Sponsor:   Yuhan Corporation
Recruiting - verified July 2017

Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis

Conditions:   Pulse Wave;   Aortic Stenosis
Interventions:   Other: Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction;   Other: Control group without heart disease
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified July 2017

Postpartum Hypertension: Remote Patient Monitoring

Condition:   Hypertension, Pregnancy-Induced
Intervention:   Other: Mobile Health
Sponsor:   University of Wisconsin, Madison
Recruiting - verified July 2017

Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers

Condition:   Opioid-Related Disorders
Intervention:   Drug: Nalmefene
Sponsor:   National Institute on Drug Abuse (NIDA)
Completed - verified July 2017

Vascular Changes in Pre-Eclamptic Patients and Its Impact on Pregnancy Outcome.

Condition:   Pre-Eclampsia
Intervention:  
Sponsor:   Beni-Suef University
Recruiting - verified July 2017

Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs Intake

Conditions:   Hypertension;   Primary Hypertension;   Non-Adherence, Medication;   Non-Adherence, Patient
Intervention:   Behavioral: SMS reminders of medicines intake
Sponsors:   Comenius University;   University of California, Los Angeles;   Research Institute for Child Psychology and Pathopsychology;   Dr. Max Pharmacies
Recruiting - verified July 2017

Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: ARN-509;   Drug: Abiraterone Acetate;   Drug: Prednisone
Sponsors:   Daniel George, MD;   Janssen Scientific Affairs, LLC
Recruiting - verified July 2017

Yoga Poses and Breath Control Cardiovascular Changes in Hypertensive Post-Menopause Women

Conditions:   Hypertension;   Postmenopausal Symptoms
Interventions:   Other: Yoga Poses;   Other: Breath Control;   Other: Stretching exercises
Sponsor:   Instituto de Cardiologia do Rio Grande do Sul
Enrolling by invitation - verified July 2017

Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension.

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Selexipag;   Drug: Placebo
Sponsor:   Actelion
Not yet recruiting - verified July 2017

Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Daily

Conditions:   Glaucoma, Primary Open Angle;   Ocular Hypertension
Interventions:   Drug: D565H(Latanoprost 25㎍/㎖);   Drug: D565(Latanoprost 50㎍/㎖)
Sponsor:   Chong Kun Dang Pharmaceutical
Recruiting - verified February 2017

ADAPT - A Patient Registry of the Real-world Use of Orenitram®

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Oral treprostinil
Sponsor:   United Therapeutics
Recruiting - verified July 2017

Clinical Characteristics, Anti-hyperglycaemic Treatment Pattern and Target Attainment of Type 2 Diabetes Mellitus Patients in Older Population With or Without Albuminuria in China

Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: No Treatment
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2017

Pharmacokinetic Drug-drug Interaction of CKD-330 and D086

Conditions:   Hypertension;   Hyperlipidemias
Interventions:   Drug: CKD-330;   Drug: D086;   Drug: CKD-330 + D086
Sponsor:   Chong Kun Dang Pharmaceutical
Completed - verified July 2017

Molecular Investigation of Genetic Factors in CArDiovascular Diseases Using an BIOresource of Healthy Volunteers

Condition:   Cardiovascular Diseases
Interventions:   Other: Eligibility and lifestyle restrictions check.;   Other: Medical history, demographic and lifestyle factors;   Other: Anthropometric measurements: height, weight, and body fat;   Other: Blood pressure and heart rate;   Other: Forearm blood flow: Visit 1 (EDNRA);   Other: Forearm blood flow: Visit 2 (EDNRA);   Other: Blood biochemistry (PNPLA3);   Other: Blood EPCR function (PROCR);   Other: Blood platelet coagulation and function (PROCR);   Other: Blood endothelial permeability (PROCR);   Other: Blood leukocyte-endothelium adhesion (PROCR);   Other: Baseline Venepuncture (PNPLA3, Visit 1);   Other: Deuterium water - Loading dose 1 (PNPLA3, Visit 1);   Other: Deuterium water - Loading dose 2 (PNPLA3, Visit 1);   Other: Energy-balanced dinner (PNPLA3, Visit 1);   Other: Fasting venepuncture (PNPLA3, Visit 2);   Other: Deuterium water - Maintenance dose (PNPLA3, Visit 2);   Other: Consumption of high carbohydrate meal (PNPLA3, Visit 2);   Other: Postprandial Venepuncture (PNPLA3, Visit 2);   Other: Venepuncture (PROCR)
Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   University of Cambridge
Not yet recruiting - verified July 2017

Single Ascending Dose Study of Safety and Tolerability of SPH3127 Tablet in Chinese Healthy Volunteers

Condition:   Hypertension
Intervention:   Drug: SPH3127
Sponsor:   Shanghai Pharmaceuticals Holding Co., Ltd
Recruiting - verified July 2017

Saline Lavage X Saline Lavage and Osteonil Plus in Rizarthritis

Conditions:   Rhizarthrosis;   Metabolic Disease
Interventions:   Behavioral: Visual Analog Scale (VAS);   Behavioral: Range of Motion (ROM);   Behavioral: Palmar grip strength;   Behavioral: Lateral grip strength;   Behavioral: Pulp-pulp pinch strength;   Drug: Lavage with physiologic saline solution;   Drug: Lavage with physiologic saline solution and Osteonil Plus®;   Behavioral: Quick Dash;   Behavioral: Sollerman Test
Sponsor:   University of Sao Paulo General Hospital
Recruiting - verified July 2017

Investigating Idiopathic Pulmonary Fibrosis in Greece (INDULGE IPF)

Condition:   Idiopathic Pulmonary Fibrosis
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2017

Comparison of Vitamin D Status and Vitamin D Receptor Polymorphisms in Patients With High Myopia and Primary Open-angle Glaucoma

Conditions:   Vitamin D Deficiency;   Primary Open-angle Glaucoma;   High Myopia;   Vitamin D Receptor Polymorphisms
Intervention:   Other: Serum levels of 1a, 25-Dihydroxyvitamin D3 were measured by an enzyme-linked immuno-absorbent assay
Sponsor:   Lv Yingjuan
Completed - verified July 2017

A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL

Condition:   Alport Syndrome
Interventions:   Drug: Placebo Oral Capsule;   Drug: Bardoxolone Methyl
Sponsor:   Reata Pharmaceuticals, Inc.
Recruiting - verified July 2017

Anticoagulation for Advanced Cirrhotic Patients After TIPS

Condition:   Liver Cirrhosis
Intervention:   Drug: Low molecular weight Heparin
Sponsor:   Fourth Military Medical University
Recruiting - verified July 2017

Cerebral Perfusion in the Beach Chair Position

Condition:   Cognitive Dysfunction
Intervention:   Device: Dual-monitoring
Sponsors:   Brisbane Hand and Upper Limb Research Institute;   The University of Queensland;   Medtronic Australasia Pty Ltd (Medtronic);   CAS Medical Systems, Inc. (CASMED)
Recruiting - verified July 2017

The Evaluation and Treatment of Elevated Left-Sided Filling Pressures by Balloon Inflation Within the IVC

Conditions:   Hypertension, Pulmonary;   Heart Failure
Intervention:   Procedure: Preventing pulm HTN during exercise
Sponsor:   Cardioflow Technologies, LLC
Recruiting - verified December 2016

Treatment of Gastric Varices Using EUS Guided Techniques

Condition:   Gastric Varix
Interventions:   Procedure: EUS-guided injection of coils with cyanoacrylate;   Procedure: EUS-guided injection of coils
Sponsor:   Instituto Ecuatoriano de Enfermedades Digestivas
Recruiting - verified July 2017

Comparison of Two Doses of Edoxaban Using Different Tests (Assays) and Clinical Outcomes

Condition:   Atrial Fibrillation
Intervention:   Drug: Edoxaban
Sponsors:   Daiichi Sankyo Inc.;   Quintiles, Inc.
Recruiting - verified July 2017

Long-term Extension Study of the Safety and Pharmacokinetics of QCC374 in PAH Patients

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: QCC374
Sponsor:   Novartis Pharmaceuticals
Not yet recruiting - verified July 2017

An Investigation Into the Effect of Liquorice Ingestion on the Salivary Cortisol to Cortisone Molar Ratio

Condition:   Apparent Mineralocorticoid Excess
Intervention:   Dietary Supplement: Liquorice
Sponsor:   The Royal Wolverhampton Hospitals NHS Trust
Recruiting - verified October 2016

A Pilot Randomized Controlled Trial to Reduce Salt Intake Among Hypertensive Young Adults in Hong Kong

Condition:   Hypertension
Interventions:   Behavioral: Four-week weekly intervention to reduce salt intake;   Other: Usual government pamphlets
Sponsor:   The University of Hong Kong
Recruiting - verified July 2017

Efficacy of Propofol vs Placebo in the Prevention of Coughing During Emergence of General Anesthesia Under Desflurane

Conditions:   Elective Surgery;   Coughing
Interventions:   Drug: Intravenous dose of 0.5 mg/kg of propofol;   Drug: Intravenous dose of 0.05 mL/kg of saline solution
Sponsor:   Centre hospitalier de l'Université de Montréal (CHUM)
Recruiting - verified October 2016

Actigraphy in Pediatric Pulmonary Hypertension

Condition:   Pediatric Pulmonary Hypertension
Intervention:   Other: No interventions / observations only
Sponsor:   University of Colorado, Denver
Recruiting - verified July 2017

Bicarbonate Administration in CKD

Conditions:   Chronic Kidney Disease;   Metabolic Acidosis
Interventions:   Drug: Sodium bicarbonate;   Drug: Placebo
Sponsor:   University of Colorado, Denver
Recruiting - verified July 2017

Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Adempas (Riociguat, BAY63-2521);   Drug: Sildenafil;   Drug: Tadalafil
Sponsor:   Bayer
Recruiting - verified July 2017

The Effect of Whey Protein and Dietary Fibers on Risk Markers of the Metabolic Syndrome and Bone Health

Conditions:   Abdominal Obesity;   Metabolic Syndrome;   Type 2 Diabetes;   Cardiovascular Disease
Interventions:   Other: Whey protein powder;   Other: Maltodextrin powder;   Other: High fiber bread;   Other: Low fiber bread
Sponsors:   Aarhus University Hospital;   University of Aarhus;   Rigshospitalet, Denmark;   University of California, Davis;   University of Copenhagen
Completed - verified July 2017

The Role of Minerelocorticoid Receptor on Modulating Aldosterone Production

Condition:   Healthy Volunteers
Interventions:   Drug: Placebo;   Drug: Fludrocortisone;   Drug: Eplerenone
Sponsor:   Brigham and Women's Hospital
Recruiting - verified July 2017

Effect of Statin Use on Aldosterone Secretion

Condition:   Healthy Subjects
Interventions:   Drug: Simvastatin;   Drug: Pravastatin;   Other: Placebo
Sponsor:   Brigham and Women's Hospital
Recruiting - verified July 2017

Efficacy of Glaucoma Drop Aids in Medication Compliance in the Patient Population at Boston Medical Center

Condition:   Glaucoma
Intervention:   Device: Eye Drop Aid
Sponsor:   Boston Medical Center
Recruiting - verified July 2017

TReatment Of Pulmonary HYpertension 1-US Study

Condition:   Pulmonary Arterial Hypertension
Intervention:   Device: Therapeutic Intra-Vascular UltraSound (TIVUS™) System
Sponsor:   SoniVie Ltd.
Recruiting - verified July 2017

Comparison of Blood Pressure Control Achieved in Antihypertensive or Generic Drugs in Moderate to Severe Hypertensive Patients

Condition:   Hypertension
Interventions:   Drug: period with drug (trade name) then period with generic;   Drug: period with generic then period with drug (trade name)
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting - verified July 2017

Non-interventional, Postauthorization Safety Study of Ventavis for Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Ventavis (Iloprost, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified July 2017

Ketamine vs. Placebo as Adjunctive Therapies for Severe Alcohol Withdrawal

Condition:   Alcohol Withdrawal
Interventions:   Drug: Ketamine;   Drug: Dexmedetomidine;   Drug: Normal saline
Sponsor:   University of Colorado, Denver
Not yet recruiting - verified July 2017

Impact of a Nutritional Intervention on Type1 Diabetes Adult With Metabolic Syndrome

Conditions:   Type 1 Diabetes;   Metabolic Syndrome
Intervention:   Behavioral: Nutritional Counseling
Sponsor:   Institut de Recherches Cliniques de Montreal
Recruiting - verified July 2017

E_Stethoscope: Portable Digital Auscultation Study on Hypertensive/Hypertensive Heart Disease Patients

Conditions:   Hypertension;   Hypertensive Heart Disease
Interventions:   Other: Electrocardiogram/Echocardiography;   Other: Portable digital auscultation
Sponsor:   National Heart Centre Singapore
Active, not recruiting - verified July 2017

Bidirectional Text Messaging for Measurement and Motivation of Medication Adherence in Hypertension, a Pilot Study

Condition:   Hypertension
Interventions:   Behavioral: Electronic Pill Bottle;   Behavioral: Bidirectional Text Messaging
Sponsor:   University of Pennsylvania
Active, not recruiting - verified July 2017

Open-label, Single Arm Trial of BI 695502 in Patients With Previously Untreated Metastatic Colorectal Cancer

Condition:   Colorectal Neoplasms
Interventions:   Drug: BI 695502;   Drug: chemotherapy
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2017

A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension.

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Adempas (Riociguat, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified July 2017

Effect of a Female Strength & Conditioning Specialist on High School Girls' Health

Conditions:   Physical Inactivity;   Low Physical Fitness
Intervention:   Other: Girls-only resistance training
Sponsor:   University of Manitoba
Recruiting - verified July 2017

The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure

Conditions:   Glaucoma, Open-angle;   Hypertension, Ocular
Intervention:   Drug: Pilocarpine
Sponsor:   University of Colorado, Denver
Recruiting - verified July 2017

Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)

Conditions:   Glaucoma, Open-Angle;   Normal Tension Glaucoma
Interventions:   Drug: brimonidine tartrate/timolol malate Ophthalmic Solution;   Drug: bimatoprost ophthalmic solution 0.01%
Sponsor:   Allergan
Active, not recruiting - verified July 2017

Cardiovascular Outcomes of Low Testosterone

Condition:   Hypogonadism
Interventions:   Drug: Acyline;   Drug: Placebo Gel;   Drug: Placebo Tablet;   Drug: Testosterone Gel;   Drug: Arimidex
Sponsor:   University of Colorado, Denver
Recruiting - verified July 2017

Antisecretory Factor (AF) Effects on Intraocular-pressure

Condition:   Glaucoma
Interventions:   Dietary Supplement: Salovum;   Dietary Supplement: Placebo
Sponsor:   St. Erik Eye Hospital
Recruiting - verified July 2017

Mindfulness-Based Blood Pressure Reduction (MB-BP) Intervention Development

Conditions:   Prehypertension;   Hypertension
Intervention:   Behavioral: MB-BP
Sponsors:   Brown University;   National Institutes of Health (NIH);   National Center for Complementary and Integrative Health (NCCIH)
Active, not recruiting - verified July 2017

A Study to Assess Long-Term Safety of the CyPass Micro-Stent in Patients Completing the COMPASS Trial

Condition:   Primary Open Angle Glaucoma (POAG)
Interventions:   Device: CyPass Micro-Stent;   Procedure: Cataract Surgery
Sponsors:   Alcon Research;   Transcend Medical, Inc.
Active, not recruiting - verified July 2017

OCEAN Registry: Obesity and Clock for Elegant Aging Registry

Conditions:   Obesity;   Circadian Dysregulation;   Aging;   Cardiovascular Disease
Intervention:  
Sponsor:   Chang Gung Memorial Hospital
Recruiting - verified July 2017

Phase II Study of Perindopril and Regorafenib in mCRC

Condition:   Metastatic Colorectal Cancer
Interventions:   Drug: Regorafenib;   Drug: Perindopril
Sponsors:   British Columbia Cancer Agency;   Bayer
Active, not recruiting - verified July 2017

An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE

Conditions:   Pulmonary Hypertension;   Interstitial Lung Disease;   Combined Pulmonary Fibrosis and Emphysema
Intervention:   Drug: Inhaled Treprostinil
Sponsor:   United Therapeutics
Enrolling by invitation - verified July 2017

Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE

Conditions:   Pulmonary Hypertension;   Interstitial Lung Disease;   Combined Pulmonary Fibrosis and Emphysema
Interventions:   Drug: Inhaled Treprostinil;   Drug: Placebo
Sponsor:   United Therapeutics
Recruiting - verified July 2017

Efficacy and Safety of Glucocorticosteroid Treatment in the Patients With Chronic Recurrent DILI

Condition:   Drug-induced Liver Injury,Chronic
Interventions:   Drug: Methylprednisolone;   Drug: Standard Treatment
Sponsor:   Beijing 302 Hospital
Recruiting - verified July 2017

A Study Investigating Routine Practice of Chronic Thromboembolic Pulmonary Hypertension Management in EMEA Countries

Condition:   Hypertension, Pulmonary
Intervention:   Other: Standard of care
Sponsor:   Bayer
Recruiting - verified July 2017

A RCT of CenteringPregnancy on Birth Outcomes

Conditions:   Pregnancy;   Preterm Birth
Intervention:   Behavioral: CenteringPregnancy
Sponsors:   Clemson University;   Greenville Health System
Recruiting - verified July 2017

ABI-009, an mTOR Inhibitor, for Patients With Severe Pulmonary Arterial Hypertension

Condition:   Pulmonary Hypertension
Intervention:   Drug: ABI-009, nab-rapamycin, albumin-bound rapamycin
Sponsor:   Aadi, LLC
Recruiting - verified July 2017

Effects of Use of a Connected Pillbox On Medication Adherence

Conditions:   Diabetes Mellitus;   Hypertension;   Hyperlipidemia
Intervention:   Device: Pre-filled trays
Sponsors:   University of Pennsylvania;   TowerView Health
Enrolling by invitation - verified July 2017

Acute Effects of rhBNP in Patients With PH Associated With Acute Exacerbation of Chronic Pulmonary Disease

Condition:   Pulmonary Hypertension
Interventions:   Drug: rhBNP;   Drug: placebo
Sponsor:   LI ZHAO
Recruiting - verified July 2017

Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular Hypertension

Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension
Intervention:   Drug: bimatoprost 0.03% plus timolol 0.5%
Sponsor:   Allergan
Recruiting - verified July 2017

Beauty From Within Community Screening Project

Condition:   Heart Health Screening and Prevention
Interventions:   Procedure: Fingerstick cholesterol test;   Other: Atherosclerosis Cardiovascular Disease Risk assessment;   Procedure: Blood pressure measurement
Sponsor:   Cedars-Sinai Medical Center
Active, not recruiting - verified July 2017

Riociguat in Children With Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsors:   Bayer;   Merck Sharp & Dohme Corp.
Recruiting - verified July 2017

Evaluation of South Africa's National Adherence Strategy

Conditions:   HIV;   Tuberculosis;   Diabetes;   Hypertension
Intervention:   Behavioral: Minimum package of interventions to improve ART adherence
Sponsors:   Boston University;   World Bank (Lead institution);   Republic of South Africa National Department of Health (Lead institution)
Recruiting - verified July 2017

Chemical Block and Electrical Stimulation of the Carotid Body to Treat Refractory Hypertension

Condition:   Hypertension
Interventions:   Device: Electrical block;   Device: Chemical block
Sponsor:   Eric Albrecht
Recruiting - verified July 2017

Safety and Efficacy Study of LHW090 in Resistant Hypertension Patients

Condition:   Patients, Resistant Hypertension
Interventions:   Drug: LHW090;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Recruiting - verified July 2017

Effects of Dietary Nitrate in Hypertensive Pregnant Women

Conditions:   Hypertension;   Pregnancy
Interventions:   Dietary Supplement: Beetroot juice;   Dietary Supplement: Nitrate-depleted beetroot juice
Sponsor:   University of Manchester
Completed - verified July 2017

Identifying Biomarkers and Cardiovascular Risk Factors in Childhood Metabolic Syndrome

Conditions:   Metabolic Syndrome;   Cardiovascular Disease
Intervention:  
Sponsor:   Chang Gung Memorial Hospital
Completed - verified July 2017

A Trial of Daily Ultraviolet Therapy to Reduce Cardiovascular Risk Factors

Condition:   Hypertension
Interventions:   Device: Ultraviolet A radiation;   Device: Sham irradiation
Sponsor:   University of Edinburgh
Recruiting - verified July 2017

TIPS vs Endoscopic Therapy for Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis

Conditions:   Portal Vein Thrombosis;   Liver Cirrhosis
Interventions:   Procedure: Transjugular intrahepatic portosystemic shunt;   Drug: Non-selective beta blockers;   Procedure: Endoscopic therapy;   Drug: Anticoagulation
Sponsors:   Fourth Military Medical University;   The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School;   Provincial Hospital Affiliated to Shandong University;   The Third Affiliated Hospital of Sun Yat-sen Universityg;   Nanfang Hospital Affiliated to Southern Medical University;   First Affiliated Hospital of Xinjiang Medical University;   The First Affiliated Hospital of Nanchang University
Recruiting - verified July 2017

Clinical Evaluation of Visco-Assisted CyPass Micro-Stent Implantation in Patients With Open Angle Glaucoma

Condition:   Open Angle Glaucoma
Interventions:   Device: CyPass Micro-Stent;   Device: CyPass Micro-Stent + 60 ul viscoelastic
Sponsor:   Transcend Medical, Inc.
Completed - verified July 2017

PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial

Condition:   Portopulmonary Hypertension
Interventions:   Drug: Macitentan;   Other: Placebo
Sponsor:   Actelion
Recruiting - verified July 2017

Non Invasive Measurements of Intracranial Pressure in Patients With Malignant Glioma

Condition:   Glioma
Intervention:   Device: noninvasive method of ICP measurements (Elios)
Sponsors:   Centre Jean Perrin;   Laboratoire de Biophysique Neurosensorielle - UMR INSERM 1107 (Pr Paul AVAN)
Recruiting - verified July 2017

Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma

Condition:   Scleroderma
Interventions:   Drug: atorvastatin;   Drug: Placebo
Sponsors:   Robyn T. Domsic, MD, MPH;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified July 2017

Radiofrequency Ablation for Multi-level Obstructive Sleep Apnea: A Single-arm, Multicenter Study

Condition:   Apnea, Sleep
Intervention:   Device: RFA treatment
Sponsor:   Olympus Surgical Technologies Europe
Recruiting - verified February 2017

Evaluation of the Utility of Telemetry in Patients Admitted for Chest Pain Who Are at Low Risk for Acute Coronary Syndrome

Conditions:   Chest Pain;   Telemetry;   Acute Coronary Syndrome;   Health Care Resource Utilization
Interventions:   Other: No Telemetry Monitoring;   Device: Telemetry Monitoring
Sponsors:   Carilion Clinic;   Johns Hopkins University;   University of Maryland;   Virginia Commonwealth University;   MedStar Health;   Virginia Tech Carilion Research Institute
Completed - verified July 2017

Chronic Hypertension and Pregnancy (CHAP) Project

Condition:   Hypertension
Interventions:   Drug: Anti-hypertensive therapy;   Other: No anti-hypertensive therapy (unless BP is severe)
Sponsors:   University of Alabama at Birmingham;   Columbia University;   Drexel University College of Medicine;   Rutgers, The State University of New Jersey;   Lehigh Valley Hospital;   Saint Peters University Hospital;   Christiana Care Health Services;   Washington University School of Medicine;   Duke University;   University of Texas Southwestern Medical Center;   The University of Texas Health Science Center, Houston;   Stanford University;   University of Pennsylvania;   The University of Texas Medical Branch, Galveston;   University of Utah;   Intermountain Health Care, Inc.;   University of California, San Francisco;   Johns Hopkins University;   University of Pittsburgh;   Ochsner Health System;   University of North Carolina, Chapel Hill;   National Heart, Lung, and Blood Institute (NHLBI);   WakeMed Health and Hospitals;   San Francisco General Hospital;   McKay-Dee Hospital;   Winthrop University Hospital;   New York Hospital Queens;   Latter Day Saints Hospital;   Lyndon B Johnson General Hospital;   Virtua Medical Group;   Bayview Medical Center;   Duke Regional Hospital;   Utah Valley Regional Medical Center;   Northwestern;   Brown (WIHRI);   Baylor College of Medicine;   Case Western/Metro Health;   Ohio State University;   University of Iowa;   University of California, San Diego;   Indiana University;   Unity Point Health-Meriter Hospital WI;   Weill Medical College of Cornell University;   University of Oklahoma;   Medical University of South Carolina
Recruiting - verified July 2017

Perioperative Assessment of Right Ventricular Function and Venous Return in Patients With Epithelial Ovarian Cancer Undergoing Cytoreductive Surgery (Gyn Right) - Pilot Study

Condition:   Right Ventricular Function and Venous Return
Intervention:  
Sponsor:   Charite University, Berlin, Germany
Withdrawn - verified July 2017

Manchester Antenatal Vascular Service

Condition:   Vascular Disease
Intervention:   Other: no intervention
Sponsors:   Central Manchester University Hospitals NHS Foundation Trust;   National Institute for Health Research, United Kingdom
Recruiting - verified July 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Placebo
Sponsors:   AstraZeneca;   FibroGen
Active, not recruiting - verified July 2017

Heart Health 4 Moms

Conditions:   Cardiovascular Disease;   Preeclampsia;   Hypertension;   Post-partum Weight Retention
Interventions:   Behavioral: Web-based educational and motivational modules;   Behavioral: Information and Screening Group
Sponsors:   Brigham and Women's Hospital;   Patient-Centered Outcomes Research Institute;   Preeclampsia Foundation
Completed - verified July 2017

OPsumit USers Registry

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Opsumit (macitentan)
Sponsor:   Actelion
Recruiting - verified July 2017

Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH )

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (ADEMPAS, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified July 2017

Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Glaucomatous Neurodegeneration

Conditions:   Retinal Degeneration;   Primary Open-Angle Glaucoma
Interventions:   Other: Subtenon administration of autologous ADRC;   Procedure: Liposuction;   Device: ADRC isolation
Sponsor:   Central Clinical Hospital with Outpatient Health Center of Business Administration for the President of Russian Federati
Enrolling by invitation - verified July 2017

Blood Pressure (BP) Visit Intensification Study

Conditions:   Blood Pressure;   Hypertension
Intervention:   Behavioral: JNC guideline training
Sponsor:   University of Rochester
Active, not recruiting - verified July 2017

EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat(BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified July 2017

Detecting and Treating High Blood Pressure in Aboriginal Population and Low and Middle Income Countries

Conditions:   Hypertension;   Cardiovascular Disease;   Diabetes
Intervention:   Other: SMS text messaging
Sponsors:   Sunnybrook Health Sciences Centre;   Canadian Institutes of Health Research (CIHR)
Recruiting - verified July 2017

Outcomes of Angiotensin Converting Enzyme Inhibitor Management Strategies Prior to Coronary Artery Bypass

Condition:   Coronary Artery Disease
Interventions:   Drug: ACE/ARB continuation;   Drug: ACE/ARB withdrawal
Sponsor:   University of Alberta
Active, not recruiting - verified July 2017

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)

Conditions:   Hypertension;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified July 5, 2017

Effects of Oral Sildenafil on Mortality in Adults With PAH

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: sildenafil citrate;   Drug: sildenafil citrate;   Drug: sildenafil citrate
Sponsor:   Pfizer
Recruiting - verified July 2017

Open-label, Multi-center Protocol to Provide QTI571 to PAH Patients Who Participated in the Extension Study (A2301E1) in Japan

Condition:   Severe Pulmonary Arterial Hypertension
Intervention:   Drug: QTI571
Sponsor:   Novartis Pharmaceuticals
Completed - verified July 2017

Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women

Conditions:   Menopause;   Aging
Interventions:   Drug: KUVAN;   Drug: Placebo;   Drug: Cetrotide;   Drug: Climara;   Drug: Placebo transdermal patch
Sponsors:   University of Colorado, Denver;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified July 2017

Social Forces to Improve Statin Adherence (Study B)

Conditions:   Medication Adherence;   High Blood Pressure;   Diabetes
Interventions:   Behavioral: Comparison to peers;   Behavioral: Adherence feedback;   Device: Electronic pill bottle
Sponsors:   University of Pennsylvania;   Merck Sharp & Dohme Corp.
Completed - verified July 2017

Essential Hypotension and Allostasis Registry

Conditions:   Blood Pressure;   Depression;   Panic Attack;   Fibromyalgia;   POTS;   Inappropriate Sinus Tachycardia;   Coronary Heart Disease;   Acute Coronary Syndrome (ACS);   Acute Myocardial Infarction (AMI);   Cerebrovascular Disease (CVD);   Transient Ischemic Attack (TIA);   Atrial Fibrillation;   Diabetes Mellitus;   Cancer;   Systolic Heart Failure;   Diastolic Heart Failure;   Chronic Fatigue Syndrome;   Syncope;   Vasovagal Syncope
Intervention:  
Sponsor:   CES University
Recruiting - verified July 2017

Treatment of Pain and Autonomic Dysreflexia in Spinal Cord Injury With Deep Brain Stimulation

Conditions:   Pain;   Autonomic Dysreflexia
Intervention:   Device: Deep Brain Stimulation
Sponsors:   Jonathan Jagid;   United States Department of Defense
Recruiting - verified July 2017

InnFocus MicroShunt Versus Trabeculectomy Study

Condition:   Primary Open Angle Glaucoma
Interventions:   Procedure: Glaucoma Surgery;   Device: InnFocus MicroShunt
Sponsor:   InnFocus Inc.
Recruiting - verified July 2017

Full Length Versus Proximal Renal Arteries Ablation

Condition:   Hypertension, Resistant to Conventional Therapy
Interventions:   Device: Thermocool®Rcatheter;   Device: Thermocool®Rcatheter
Sponsor:   The Second Affiliated Hospital of Chongqing Medical University
Completed - verified July 2017

Hypertension Control Program in Argentina (HCPIA)

Condition:   Hypertension
Intervention:   Behavioral: Comprehensive Intervention
Sponsors:   Tulane University;   National Heart, Lung, and Blood Institute (NHLBI);   Institute for Clinical Effectiveness and Health Policy
Completed - verified July 2017

A Study of Tadalafil in Pediatric Participants With Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Interventions:   Drug: Tadalafil;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting - verified July 2017

Resting Energy Expenditure Using a Handheld Calorimeter

Condition:   Obesity
Intervention:  
Sponsor:   University of British Columbia
Completed - verified July 2017

Telemonitoring of Hypertensive Patients

Condition:   Hypertension
Intervention:   Other: Telemonitoring of self-measured blood pressure
Sponsor:   Katholieke Universiteit Leuven
Not yet recruiting - verified July 2017

Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger Syndrome

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Macitentan 10 mg tablet, once daily.
Sponsor:   Actelion
Active, not recruiting - verified July 2017

Continuous Glucose Monitoring in Women With Type 1 Diabetes in Pregnancy Trial

Condition:   Type 1 Diabetics Who Are Pregnant or Planning Pregnancy
Intervention:   Device: CGM
Sponsors:   Mount Sinai Hospital, Canada;   Sunnybrook Research Institute;   Jaeb Center for Health Research;   Cambridge University Hospitals NHS Foundation Trust;   University of Cambridge
Completed - verified July 2017

Evaluation of Lysine-Specific Demethylase 1

Condition:   Hypertension
Interventions:   Drug: Para-aminohippuric Acid;   Drug: Angiotensin II
Sponsor:   Brigham and Women's Hospital
Withdrawn - verified July 2017

Resveratrol and the Metabolic Syndrome

Conditions:   Obesity;   Insulin Resistance;   Metabolic Syndrome
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: Resveratrol
Sponsor:   Rockefeller University
Active, not recruiting - verified July 2017

A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn

Condition:   Pulmonary Hypertension, Familial Persistent, of the Newborn
Interventions:   Drug: placebo;   Drug: iv sildenafil
Sponsor:   Pfizer
Recruiting - verified July 2017

The Effects of California Strawberries on Parameters of Cardiovascular Health

Conditions:   Childhood Obesity;   Cardiovascular Disease
Interventions:   Dietary Supplement: flavonoid-rich freeze-dried strawberry powder;   Dietary Supplement: macronutrient-matched control powder
Sponsor:   University of California, Davis
Completed - verified July 2017

Placental Growth and Adverse Pregnancy Outcomes

Conditions:   Hypertension Induced by Pregnancy;   Pre-Eclampsia;   IUGR
Intervention:  
Sponsor:   University of Pennsylvania
Completed - verified July 2017

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2017

Non-invasive Diagnostics of Pulmonary Hypertension With Dual Energy Computed Tomography

Condition:   Pulmonary Arterial Hypertension
Intervention:   Radiation: Dual-energy computed tomography investigation
Sponsors:   Medical University of Graz;   Ludwig Boltzmann Gesellschaft
Completed - verified July 2017

The Health Access and Recovery Peer Program

Conditions:   Hypertension;   Arthritis;   Coronary Artery Disease;   Hepatitis;   Diabetes;   Asthma;   Hyperlipidemia;   HIV
Intervention:   Behavioral: HARP Intervention
Sponsors:   Emory University;   National Institute of Mental Health (NIMH)
Completed - verified July 2017

Cardiovascular Inflammation Reduction Trial

Condition:   Cardiovascular Disease
Interventions:   Drug: Methotrexate;   Drug: Placebo
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2017

The Effect of Clevidipine on Intracranial Pressure and Cerebral Perfusion Pressure (CCP) in Brain Injured Patients

Condition:   Hypertension
Intervention:   Drug: clevidipine butyrate
Sponsors:   Columbia University;   The Medicines Company
Withdrawn - verified July 2017

Effect of Prophylactic Aqueous Suppression on Hyperencapsulation of Ahmed Glaucoma Valves

Condition:   Glaucoma
Intervention:   Drug: Aqueous Suppressant Eye Drops
Sponsors:   Credit Valley EyeCare;   Canadian Glaucoma Clinical Research Council
Recruiting - verified July 2017

Post-Authorisation Safety Cohort Observation of RetacritTM (Epoetin Zeta) Administered Subcutaneously for the Treatment of Renal Anaemia

Conditions:   Renal Anemia;   Pregnancy;   Lactation
Intervention:  
Sponsors:   Pfizer;   Hospira, now a wholly owned subsidiary of Pfizer
Recruiting - verified July 2017

Pravastatin for Prevention of Preeclampsia

Condition:   Preeclampsia
Interventions:   Drug: Pravastatin;   Drug: Placebo
Sponsors:   The University of Texas Medical Branch, Galveston;   University of Texas;   University of Pittsburgh;   Northwestern University
Recruiting - verified July 2017

A Pharmacokinetics Study for Pediatric Participants With Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Tadalafil- Tablet
Sponsor:   Eli Lilly and Company
Recruiting - verified July 2017

Prehypertension Labeling

Condition:   Prehypertension
Interventions:   Behavioral: Labeled prehypertension;   Behavioral: Unlabeled prehypertension
Sponsor:   Columbia University
Terminated - verified July 2017

Renal Sympathetic Modification in Patients With Essential Hypertension

Condition:   Essential Hypertension
Intervention:   Procedure: renal sympathetic modification
Sponsors:   The Second Affiliated Hospital of Chongqing Medical University;   Jiangsu Provincial People's Hospital;   Zunyi Medical College;   Chongqing Medical University
Recruiting - verified July 2017

A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV)

Conditions:   Congenital Cytomegalovirus Infection;   Maternal Cytomegalovirus Infection
Interventions:   Drug: CMV hyperimmune globulin;   Other: Placebo
Sponsors:   The George Washington University Biostatistics Center;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified July 2017

Longitudinal Study of Dental Implant Therapy in HIV- Positive Patients

Condition:   Peri-Implantitis
Intervention:  
Sponsors:   University of Alabama at Birmingham;   Dentsply Sirona Implants
Active, not recruiting - verified July 2017

Phaco vs. Phaco-ELT vs. Phaco-Trabectome 12m

Conditions:   Glaucoma;   Cataract
Interventions:   Procedure: phaco;   Procedure: phaco-ELT;   Procedure: phaco-Trabectome
Sponsor:   University of Zurich
Completed - verified July 2017

An Analysis of Diabetes Control in Puerto Rico

Conditions:   Diabetes Mellitus;   Arterial Hypertension;   Hypercholesterolemia
Intervention:   Other: Epidemiological intervention
Sponsors:   Center for Diabetes Control, Inc.;   Novo Nordisk A/S;   Eli Lilly and Company
Completed - verified July 2017

Study: Effects of Strawberries on Blood Pressure

Condition:   Pre-hypertension
Interventions:   Other: Strawberry Beverage;   Other: Placebo
Sponsors:   University of California, Davis;   California Strawberry Commission
Completed - verified July 2017

Support for Cardiovascular Health in African American Primary Care Patients

Conditions:   Cardiovascular Diseases;   Blood Pressure
Interventions:   Behavioral: Peer Coach Phone Calls;   Behavioral: Health Educator Visits;   Other: written materials
Sponsors:   University of Pennsylvania;   Robert Wood Johnson Foundation;   Pfizer
Completed - verified July 2017

A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension

Condition:   Hypertension, Pulmonary
Interventions:   Drug: Simvastatin;   Drug: Aspirin;   Drug: Placebo
Sponsors:   University of Pennsylvania;   National Heart, Lung, and Blood Institute (NHLBI)
Terminated - verified July 2017