High Blood Pressure

Clinical Trial Finder

Many patients with high blood pressure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Phase 3 Pharmacokinetic Study of TAK-536 in Pediatric Patients 6 to Less Than 16 Years With Hypertension

Condition:   Pediatric Hypertension
Interventions:   Drug: TAK-536 5 mg;   Drug: TAK-536 10 mg
Sponsor:   Takeda
Not yet recruiting - verified May 2015

The Role of Acupuncture for the Treatment of Obstructive Sleep Apnea in Patients With Hypertension

Condition:   Sleep Apnea, Obstructive
Intervention:   Other: acupuncture
Sponsor:   University of Pernambuco
Recruiting - verified May 2015

Cardiovascular Epidemiology in Russian Federation

Conditions:   Hypertension;   Coronary Artery Disease;   Diabetes;   Heart Failure;   Smoking;   Lifestyle
Intervention:  
Sponsors:   Federal North-West Medical Research Centre;   National Research Center for Preventive Medicine;   Russian Cardiology Research and Production Center
Recruiting - verified May 2015

Prospective Safety and Tolerability Assessment of a Cardiovascular Health Dietary Supplement

Condition:   Hypertension
Intervention:   Dietary Supplement: Cardiovascular health dietary supplement
Sponsor:   National College of Natural Medicine
Not yet recruiting - verified May 2015

Prevention of Severe Postpartum Hypertension

Condition:   Hypertension
Interventions:   Drug: Furosemide;   Drug: Potassium chloride;   Drug: Placebo #1;   Drug: Placebo #2
Sponsor:   Washington University School of Medicine
Not yet recruiting - verified May 2015

The Effect of Magnesium on Maternal Mood, Cognitive Function, and Birth Experience

Condition:   Depression, Postpartum
Intervention:   Drug: Magnesium Sulfate
Sponsor:   Northwestern University
Not yet recruiting - verified May 2015

A Phase 2 Exploratory Study of CS-3150 in Japanese Hypertensive Patients With Moderate Renal Impairment

Condition:   Hypertension
Intervention:   Drug: CS-3150
Sponsor:   Daiichi Sankyo Inc.
Recruiting - verified May 2015

Improving Adherence and Outcomes by Artificial Intelligence-Adapted Text Messages

Condition:   Medication Non-adherence
Intervention:   Behavioral: SMS (Text messages)
Sponsors:   University of Michigan;   Agency for Healthcare Research and Quality (AHRQ)
Not yet recruiting - verified October 2014

Effectiveness of Four Popular Diet Strategies for Weight Loss and Cardiac Risk Reduction

Conditions:   Obesity;   Cardiovascular Disease;   Metabolic Syndrome
Interventions:   Behavioral: Atkins Diet;   Behavioral: Zone Diet;   Behavioral: Weight Watchers Diet;   Behavioral: Ornish Diet
Sponsor:   Tufts Medical Center
Completed - verified May 2015

Prenatal Inflammation and Perinatal Outcomes

Condition:   Pregnancy
Intervention:   Biological: inactivated seasonal flu vaccine
Sponsors:   University of Calgary;   Northwestern University
Not yet recruiting - verified May 2015

Study of Anemia in Chronic Kidney Disease (CKD) Among High-Risk Hypertensive and Diabetic Patients in Pakistan

Conditions:   Anemia;   Diabetes;   Kidney Disease;   Chronic;   Hypertension
Intervention:  
Sponsor:   Hoffmann-La Roche
Completed - verified May 2015

Clinical Evaluation of Visco-Assisted CyPass Micro-Stent Implantation in Patients With Open Angle Glaucoma

Condition:   Open Angle Glaucoma
Interventions:   Device: CyPass Micro-Stent;   Device: CyPass Micro-Stent + 60 ul viscoelastic
Sponsor:   Transcend Medical, Inc.
Recruiting - verified May 2015

Prospective, Non-interventional, Multi-center, Post-authorization Safety Study of Riociguat for Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (ADEMPAS, BAY63-2521)
Sponsor:   Bayer
Not yet recruiting - verified May 2015

The Impact of Metabolic Syndrome on Patients Undergoing Elective Laparotomy

Conditions:   Metabolic Syndrome;   Anesthesia;   Perioperative Outcome;   Complications
Intervention:   Procedure: Elective abdominal surgery
Sponsor:   University of Ioannina
Completed - verified May 2015

U.S. CTEPH Registry

Conditions:   Chronic Thromboembolic Pulmonary Hypertension (CTEPH);   Pulmonary Hypertension
Intervention:  
Sponsors:   University of California, San Diego;   E Squared Trials and Registries, Inc.
Recruiting - verified May 2015

Post-marketing Surveillance of Lenvatinib Mesylate (Lenvima Capsule) in Patients With Unresectable Thyroid Cancer (Study LEN01T)

Condition:   Thyroid Neoplasms
Intervention:   Drug: Lenvatinib
Sponsor:   Eisai Co., Ltd.
Recruiting - verified May 2015

On-Line Intervention For Promoting Healthy Habits And Weight Loss In Hypertensive Patients

Condition:   Obesity
Intervention:   Behavioral: Lifestyle on-line intervention
Sponsors:   Universitat Jaume I;   University of Valencia;   Cardenal Herrera University
Active, not recruiting - verified May 2015

RAS Peptide Profiles in Patients With Arterial Hypertension

Condition:   Essential Hypertension
Interventions:   Drug: Perindopril;   Drug: Olmesartan;   Drug: Amlodipine;   Drug: Hydrochlorothiazide
Sponsor:   University Hospital, Basel, Switzerland
Recruiting - verified May 2015

Japanese Phase 3 Study of Aflibercept in Neovascular Glaucoma Patients

Condition:   Glaucoma, Neovascular
Interventions:   Drug: Aflibercept (Eylea, BAY 86-5321);   Drug: Sham Injection
Sponsors:   Bayer;   Regeneron Pharmaceuticals
Recruiting - verified May 2015

Lowering Blood Pressure in Primary Care in Vienna

Condition:   Hypertension
Intervention:   Drug: Olmesartan medoxomil, amlodipine, hydrochlorothiazide
Sponsors:   Wilhelminenspital Vienna;   Association for the Promotion of Research in Atherosclerosis, Thrombosis and Vascular Biology ;   Ludwig Boltzmann Foundation for Cardiovascular Research
Recruiting - verified May 2015

Does Benign Prostatic Obstruction Cause Hypertension?

Conditions:   Prostatic Hyperplasia;   Hypertension
Intervention:   Procedure: 24-hr ambulatory blood pressure measurement
Sponsors:   St. Olavs Hospital;   Norwegian University of Science and Technology
Recruiting - verified May 2015

Comparison of IOP (Intraocular Pressure)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution

Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: Brinzolamide 1%/Timolol maleate 0.5% fixed combination ophthalmic suspension;   Drug: Dorzolamide hydrochloride 1%/Timolol maleate 0.5% ophthalmic solution;   Drug: Subject's habitual PGA monotherapy
Sponsor:   Alcon Research
Recruiting - verified May 2015

Self-management of Postnatal Anti-hypertensive Treatment: a Trial Development Pilot Study

Conditions:   Pre-Eclampsia;   Hypertension, Pregnancy-Induced
Intervention:   Other: Self-management of postnatal anti-hypertensive treatment
Sponsors:   University of Oxford;   National Institute for Health Research, United Kingdom
Recruiting - verified May 2015

A Phase 2b Study of GCS-100 in Patients With Chronic Kidney Disease Caused by Diabetes

Condition:   Diabetic Chronic Kidney Disease
Interventions:   Drug: GCS-100;   Drug: Placebo
Sponsor:   La Jolla Pharmaceutical Company
Active, not recruiting - verified May 2015

Follow-up Study of Complications of Acute Pancreatitis

Conditions:   Pancreatitis;   Pancreatic Neoplasms;   Metabolic Diseases;   Hypertension, Portal;   Respiratory Failure;   Quality of Life
Intervention:  
Sponsor:   The First Affiliated Hospital of Nanchang University
Recruiting - verified November 2014

Chronic Hypertension and Pregnancy (CHAP) Project

Condition:   Hypertension
Interventions:   Other: Anti-hypertensive therapy;   Other: No to low dose anti-hypertensive therapy
Sponsors:   University of Alabama at Birmingham;   Columbia University;   Drexel University College of Medicine;   Rutgers, The State University of New Jersey;   Lehigh Valley Hospital;   Saint Peters University Hospital;   Christiana Care Health Services;   Washington University School of Medicine;   Duke University;   University of Texas Southwestern Medical Center;   The University of Texas Health Science Center, Houston;   Stanford University;   University of Pennsylvania;   The University of Texas Medical Branch, Galveston;   University of Utah;   Intermountain Health Care, Inc.;   University of California, San Francisco;   Johns Hopkins University;   University of Pittsburgh;   Ochsner Health System;   University of North Carolina, Chapel Hill;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified February 2015

Effect of Two Diets With Different Content of Protein on Weight Loss in Adults With Metabolic Syndrome

Conditions:   Metabolic Syndrome X;   Weight Loss
Intervention:   Other: High protein diet
Sponsor:   Mexican National Institute of Public Health
Enrolling by invitation - verified May 2015

Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years

Condition:   PAH
Intervention:   Drug: oral treprostinil
Sponsor:   United Therapeutics
Recruiting - verified April 2015

Evaluation of Stendo Pulsating Suit on Microcirculation and Central Blood Pressure in Essential Hypertension Patients

Condition:   Essential Hypertension
Intervention:   Device: Stendo pulsating suit System
Sponsor:   Stendo
Recruiting - verified October 2014

Phase III Trial BI 695502 Plus Chemotherapy vs. Avastin® Plus Chemotherapy in Patients With Lung Cancer

Condition:   Carcinoma, Non-Small-Cell Lung
Interventions:   Drug: Chemotherapy;   Drug: BI 695502;   Drug: bevacizumab;   Drug: Chemotherapy
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified May 2015

Effects of Inspiratory Muscle Training on Blood Pressure Levels in Hypertensive Individuals

Condition:   Hypertension
Interventions:   Other: Inspiratory muscle training (IMT);   Other: Sham IMT
Sponsor:   Hospital de Clinicas de Porto Alegre
Recruiting - verified May 2015

A Phase 4 Study of Regorafenib in Metastatic Colorectal Cancer - Does Educating Physicians Change Patient Out Comes?

Condition:   Physician Education
Intervention:   Drug: Regorafenib (Stivarga, BAY 73-4506)
Sponsor:   Bayer
Recruiting - verified May 2015

Cardiovascular and Renal Risk in Spain

Condition:   Cardiovascular Disease
Intervention:   Other: No treatment
Sponsor:   La Sociedad Española de Médicos de Atención Primaria
Recruiting - verified October 2014

Efficacy Study of Diacerein on Glycemic Control and Liver Fat in Type 2 Diabetes Subjects

Conditions:   Type 2 Diabetes.;   Non-alcoholic Fatty Liver Disease
Interventions:   Drug: Diacerein;   Drug: Placebo
Sponsors:   Universidade Federal do Rio de Janeiro;   Rio de Janeiro State Research Supporting Foundation (FAPERJ)
Recruiting - verified May 2015

HeartMate III™ IDE Clinical Study Protocol

Condition:   Advanced Refractory Left Ventricular Heart Failure
Interventions:   Device: HeartMate III LVAS;   Device: HeartMate II LVAS
Sponsor:   Thoratec Corporation
Recruiting - verified May 2015

Extended Pouch Roux-en-Y Gastric Bypass Study

Condition:   Morbid Obesity
Interventions:   Procedure: Extended Pouch RYGB;   Procedure: Standard RYGB
Sponsor:   Rijnstate Hospital
Recruiting - verified August 2014

A Cluster-randomized Controlled Knowledge Translation Feasibility Study in Alberta Community Pharmacies

Condition:   Chronic Diseases
Intervention:   Behavioral: Task-focused facilitation
Sponsors:   University of Alberta;   Alberta Innovates Health Solutions;   University of Waterloo;   University of Mississippi Medical Center
Active, not recruiting - verified May 2015

24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension

Conditions:   Diabetes Mellitus, Type 2;   Hypertension
Interventions:   Drug: Empagliflizon low dose;   Drug: placebo;   Drug: Empagliflizon high dose
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified May 2015

Diuretic Comparison Project

Condition:   Hypertension
Interventions:   Drug: Hydrochlorothiazide;   Drug: Chlorthalidone
Sponsor:   Department of Veterans Affairs
Not yet recruiting - verified May 2015

Pharmacological Predictors of Successful Cyclosporine Acute GVHD Prophylaxis in Children Undergoing HSCT

Condition:   PHARMACOLOGICAL PREDICTORS OF SUCCESSFUL CYCLOSPORINE ACUTE GRAFT VERSUS HOST DISEASE PROPHYLAXIS IN CHILDREN UNDERGOING HAEMATOPOIETIC STEM CELL TRANSPLANT
Intervention:  
Sponsors:   Lee Dupuis;   C17 Council
Recruiting - verified May 2015

Comparison of Resin Salve and Octenidine in Patients With Neuropathic Diabetic Foot Ulcers

Conditions:   Diabetes Mellitus;   Diabetes Complications;   Diabetic Neuropathies;   Wound Infection
Interventions:   Device: Resin salve treatment;   Device: Octenidine treatment
Sponsors:   Janne J. Jokinen;   Repolar Ltd.
Completed - verified May 2015

Treatment of Masked Hypertension

Conditions:   Masked Hypertension;   Hypertension;   Chronic Renal Insufficiency
Interventions:   Other: Antihypertensive medication intensification;   Other: Usual care
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified May 2015

Healing and Empowering Alaskan Lives Towards Healthy-Hearts Study

Condition:   Tobacco Dependence
Interventions:   Behavioral: Counselor intervention for tobacco/physical activity;   Drug: Nicotine replacement therapy;   Behavioral: Intervention for managing hypertension/hypercholesterolemia
Sponsors:   Stanford University;   University of California, San Francisco;   Alaska Native Tribal Health Consortium;   University of Alaska Anchorage;   Norton Sound Health Corporation
Not yet recruiting - verified May 2015

Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus

Conditions:   Uremic Pruritus;   Pruritus
Interventions:   Drug: nalbuphine HCl ER 60mg BID;   Drug: nalbuphine HCl ER 90mg BID;   Drug: nalbuphine HCl ER 120mg BID
Sponsor:   Trevi Therapeutics
Recruiting - verified May 2015

Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

Conditions:   Uremic Pruritus;   Pruritus
Interventions:   Drug: nalbuphine HCl ER tablets 60 mg BID;   Drug: nalbuphine HCl ER tablets 120mg BID;   Drug: Placebo tablets BID
Sponsor:   Trevi Therapeutics
Active, not recruiting - verified May 2015

Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (ADEMPAS, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified May 2015

Comprehensive Lifestyle Modification for Patients With Hypertension and Metabolic Syndrome: a Multicenter Randomized Controlled Trial

Conditions:   Hypertension;   Metabolic Syndrome
Interventions:   Behavioral: Comprehensive Lifestyle Modification;   Behavioral: DASH
Sponsors:   Universität Duisburg-Essen;   Kliniken Essen-Mitte;   Immanuel Hospital Berlin, Berlin, Germany;   Charité University Medical Center, Berlin, Germany;   University of Witten/Herdecke
Active, not recruiting - verified May 2015

EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat(BAY63-2521)
Sponsor:   Bayer
Recruiting - verified May 2015

Neural Mechanism of Aldosterone-induced Insulin Resistance

Condition:   Hypertension
Interventions:   Drug: DEFINITY® infusion;   Drug: Human Recombinant Regular Insulin infusion;   Drug: Dextrose infusion;   Procedure: Flow mediated vasodilation;   Procedure: Endothelial cell collection;   Procedure: Microvascular perfusion assessment using Definity;   Procedure: Microneurography
Sponsor:   University of Texas Southwestern Medical Center
Recruiting - verified May 2015

Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension Due to Left Ventricular Dysfunction

Conditions:   Pre-capillary Pulmonary Hypertension;   Post-capillary Pulmonary Hypertension;   Left Ventricular Dysfunction
Interventions:   Drug: Macitentan;   Drug: Placebo
Sponsor:   Actelion
Recruiting - verified May 2015

Health Coaching for Glaucoma Patients

Condition:   Glaucoma
Intervention:   Behavioral: Health Coach
Sponsor:   Duke University
Completed - verified October 2014

Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Hypertension
Interventions:   Drug: Renal nerve denervation;   Device: Cryoablation
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified May 2015

To Evaluate the Effect of Liraglutide on Ambulatory Blood Pressure-A Pilot Study

Conditions:   Diabetes Mellitus, Non-Insulin-Dependent;   Hypertensive Disease
Intervention:   Drug: Liraglutide or Placebo
Sponsors:   Tulane University Health Sciences Center;   Novo Nordisk A/S
Recruiting - verified May 2015

Effects of Oral Sildenafil on Mortality in Adults With PAH

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: sildenafil citrate;   Drug: sildenafil citrate;   Drug: sildenafil citrate
Sponsor:   Pfizer
Recruiting - verified May 2015

Effect of Renin-angiotensin-system Blockade on Urinary Free Light Chains in Patients With Type 2 Diabetes Mellitus

Conditions:   Type 2 Diabetes;   Hypertension
Intervention:   Drug: amlodipine, hydralazine, terazosin or hydrochlorothiazide
Sponsor:   Tulane University Health Sciences Center
Recruiting - verified May 2015

Meta-Analyses of the Effect of Vegetable Protein for Animal Protein on Cardiometabolic Risk

Conditions:   Diabetes;   Prediabetes;   Metabolic Syndrome;   Dysglycemia;   Overweight;   Obesity;   Dyslipidemia;   Hypertension;   Gout;   Non-alcoholic Fatty Liver Disease (NAFLD);   Kidney Disease;   Kidney Injury;   Cardiovascular Disease
Intervention:  
Sponsors:   John Sievenpiper;   Canadian Institutes of Health Research  (CIHR);   Canada Research Chairs Endowment of the Federal Government of Canada;   Loblaw Companies Limited
Active, not recruiting - verified May 2015

IOP Patterns in Ocular Hypertensive Patients Newly Converted to Glaucoma vs Stable Ocular Hypertensive Patients

Condition:   Ocular Hypertension
Intervention:   Device: Sensimed Triggersfish®
Sponsors:   Sensimed AG;   Yale University
Recruiting - verified May 2015

UAB Center of Research Translation (CORT) Project 2: The Effects of Urate Lowing Therapy (ULT) in Inflammation, Endothelial Function, and Blood Pressure

Conditions:   Pre-hypertension;   JNC 7 Stage I Hypertension
Interventions:   Drug: Allopurinol;   Drug: Placebo
Sponsors:   University of Alabama at Birmingham;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified May 2015

Global DuoTrav® Study

Conditions:   Open Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: Beta-blocker monotherapy;   Drug: Travoprost 0.004% / timolol 0.5% fixed combination ophthalmic solution
Sponsor:   Alcon Research
Completed - verified May 2015

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Conditions:   Retinal Dystrophies;   Retinitis Pigmentosa;   Glaucoma
Intervention:  
Sponsor:   Sheba Medical Center
Recruiting - verified May 2015

Human Optokinetic Contrast Device (HOCD) to Measure Visual Function and Identify Patients With and Without Glaucoma

Condition:   Glaucoma
Intervention:   Device: HOCD
Sponsor:   Benjamin Frankfort, MD, PhD
Recruiting - verified May 2015

Pharmaceutical Care in Emergency Department

Conditions:   Medication Adherence;   Hypertension;   Diabetes Mellitus
Intervention:   Other: Pharmaceutical care
Sponsors:   Hospital Moinhos de Vento;   Ministry of Health, Brazil
Completed - verified May 2015

A Prospective Randomized, Double-Blind, Placebo-Controlled Trial Comparing VitroGro® ECM to Placebo in Patients With Venous Leg Ulcers

Condition:   Venous Leg Ulcer
Interventions:   Drug: VitroGro® ECM;   Drug: Dulbecco's Phosphate Buffered Saline
Sponsor:   Tissue Therapies Ltd.
Not yet recruiting - verified May 2015

CAndesartan vs LIsinopril Effects on the BRain

Conditions:   Hypertension;   Mild Cognitive Impairment
Interventions:   Drug: Candesartan;   Drug: Lisinopril
Sponsors:   Ihab M. Hajjar;   National Institute on Aging (NIA)
Recruiting - verified May 2015

Treatment of Pain and Autonomic Dysreflexia in Spinal Cord Injury With Deep Brain Stimulation

Conditions:   Pain;   Autonomic Dysreflexia
Intervention:   Device: Deep Brain Stimulation
Sponsors:   Jonathan Jagid;   Department of Defense
Recruiting - verified May 2015

Morning Versus Evening Dosing of Antihypertensive Medications: A Pilot Study to Assess Feasibility and Efficacy

Condition:   Hypertension
Intervention:   Behavioral: Medication therapy management
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Active, not recruiting - verified May 2015

Is a Smartphone Application Effective as an Oral Medication Adherence Aid

Conditions:   Hypertension;   Diabetes;   Dyslipidemia
Intervention:   Other: Medication Adherence Smartphone App
Sponsor:   University of Arkansas
Recruiting - verified May 2015

Abiraterone Acetate for Castrate Resistant Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Abiraterone;   Drug: Prednisone
Sponsor:   Massachusetts General Hospital
Recruiting - verified May 2015

Non-interventional Study on Compliance of Inhaled Treatment With Ventavis in Patient With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Iloprost (Ventavis, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified May 2015

Mechanisms of Intradialytic Hypertension

Conditions:   Renal Failure Chronic Requiring Hemodialysis;   Haemodialysis-induced Symptom;   Hypertension
Interventions:   Other: Mindfulness Meditation;   Other: Health Education
Sponsors:   Emory University;   Satellite Healthcare
Recruiting - verified May 2015

A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurrence

Conditions:   Persistent Atrial Fibrillation;   Paroxysmal Atrial Fibrillation;   Hypertension;   Renal Denervation;   Cardiac Ablation
Interventions:   Device: Renal Artery Ablation Catheter;   Device: Cardiac Ablation
Sponsor:   St. Jude Medical
Recruiting - verified May 2015

Inhaled Budesonide for Non-ventilated Infants at High Risk of Bronchopulmonary Dysplasia: the i-BUD Pilot Study

Condition:   Bronchopulmonary Dysplasia
Intervention:   Drug: Inhaled budesonide
Sponsor:   Dr. Michael Dunn
Not yet recruiting - verified May 2015

Validation of Child-Turcotte-Pugh-Kumar (CTPK) Score in Predicting Short Term Mortality in Patients With Liver Cirrhosis

Condition:   Cirrhosis
Intervention:  
Sponsor:   Sir Ganga Ram Hospital
Recruiting - verified May 2015

AC-055-402: An Extension of AC-055-401, Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Macitentan
Sponsor:   Actelion
Active, not recruiting - verified May 2015

Multicenter Post-Approval Study Of The Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery

Condition:   Primary Open Angle Glaucoma
Interventions:   Device: iStent;   Procedure: Cataract surgery
Sponsor:   Glaukos Corporation
Recruiting - verified May 2015

Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket Cohort

Condition:   Primary Open Angle Glaucoma
Intervention:  
Sponsor:   Glaukos Corporation
Completed - verified May 2015

SYMPHONY: A Study of Macitentan in Pulmonary Arterial Hypertension to Validate the PAH-SYMPACT

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Macitentan
Sponsor:   Actelion
Active, not recruiting - verified May 2015

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Condition:   Kidney Transplantation
Interventions:   Drug: Belatacept;   Drug: Tacrolimus;   Drug: Cyclosporine
Sponsor:   Bristol-Myers Squibb
Recruiting - verified March 2015

Myfortic in High MELD Liver Transplantation

Condition:   High Model for End-Stage Liver Disease (MELD) Score
Interventions:   Drug: Everolimus, Myfortic and Tacrolimus;   Drug: Myfortic and Tacrolimus
Sponsor:   University of Colorado, Denver
Active, not recruiting - verified March 2013

Inflammation and Glycation in a General Adult Population

Condition:   Inflammation
Intervention:  
Sponsors:   Hospital Clinico Universitario de Santiago;   Medtronic
Completed - verified May 2015

Comparison of Ultrafast Echo With Echotracking

Conditions:   Essential Untreated Hypertension;   Healthy Volunteers
Intervention:  
Sponsor:   French Cardiology Society
Active, not recruiting - verified May 2015

Evaluation of Hypertension as a Predictor of Efficacy Bevacizumab in Metastatic Breast Cancer and Metastatic Colorectal Cancer

Conditions:   Metastatic Colorectal Cancer;   Metastatic Breast Cancer
Intervention:  
Sponsors:   Spanish Breast Cancer Research Group;   Roche Farma, S.A
Recruiting - verified June 2013

Scripps Wired for Health Study

Conditions:   Diabetes;   Hypertension;   Cardiac Arrhythmia
Interventions:   Device: Withings Blood Pressure monitor;   Device: iBG Star Blood Glucose Monitor;   Device: Alive Cor Portable ECG mopnitor;   Behavioral: Diese Management Program
Sponsors:   Scripps Translational Science Institute;   Scripps Health
Completed - verified May 2015

A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn

Condition:   Pulmonary Hypertension, Familial Persistent, of the Newborn
Interventions:   Drug: placebo;   Drug: iv sildenafil
Sponsor:   Pfizer
Recruiting - verified May 2015

Effect of Long Biliopancreatic Limb RYGB on Weight Loss and Comorbidities

Condition:   Morbid Obesity
Intervention:   Procedure: Roux-en-Y Gastric Bypass
Sponsor:   Rijnstate Hospital
Active, not recruiting - verified March 2014

Risk Factors for Glaucoma in Musicians

Condition:   Glaucoma
Intervention:  
Sponsors:   Henny Beckers;   Stichting Glaucoomfonds
Completed - verified May 2015

Sleep Disorders in Pediatric Dialysis

Condition:   Chronic Kidney Disease (CKD)
Intervention:  
Sponsor:   The Hospital for Sick Children
Completed - verified May 2015

Micro-Clinic Obesity and Metabolic Risk Prevention Program

Conditions:   Diabetes Mellitus, Type II;   Heart Disease;   Obesity;   Hypertension;   Dyslipidemia
Intervention:   Behavioral: Microclinic Diabetes Education Program
Sponsors:   Microclinic International;   Bell County Department of Health, Kentucky
Completed - verified May 2015

Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension

Conditions:   Pulmonary Arterial Hypertension;   Hypertension, Pulmonary
Intervention:   Drug: Sildenafil
Sponsor:   Pfizer
Recruiting - verified May 2015

Meta-analyses of Fructose-containing Sugars and Incident Cardiometabolic Disease

Conditions:   Overweight;   Obesity;   Dyslipidemia;   Hyperlipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Gout;   Hypertension;   Metabolic Syndrome;   Coronary Heart Disease;   Cardiovascular Disease
Intervention:  
Sponsors:   John Sievenpiper;   Calorie Control Council;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research  (CIHR)
Active, not recruiting - verified May 2015

Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis

Condition:   Focal Segmental Glomerulosclerosis
Interventions:   Drug: RE-021 (Sparsentan);   Drug: Irbesartan
Sponsor:   Retrophin, Inc.
Recruiting - verified April 2015

Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome

Conditions:   Diabetes;   Prediabetes;   Dysglycemia;   Overweight;   Obesity;   Dyslipidemia;   Hypertension;   Metabolic Syndrome;   Cardiovascular Diseases
Intervention:   Other: Tree nuts
Sponsors:   John Sievenpiper;   The International Tree Nut Council Nutrition Research & Education Foundation;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research  (CIHR)
Completed - verified May 2015

An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: UT-15C (treprostinil diethanolamine)
Sponsor:   United Therapeutics
Recruiting - verified May 2015

Trial of the Early Combination of Oral Treprostinil With Background Oral Monotherapy in Subjects With Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: UT-15C (treprostinil diethanolamine);   Drug: Placebo
Sponsor:   United Therapeutics
Recruiting - verified May 2015

IOP Fluctuations in Primary Open Angle Glaucoma Patients Before and After Deep Sclerectomy With Collagen Implant

Condition:   Primary Open Angle Glaucoma
Intervention:   Device: SENSIMED Triggerfish®
Sponsors:   Sensimed AG;   Clinique Monchoisi
Terminated - verified May 2015

Predictors of Pulmonary Hypertension Risk in Premature Infants With Bronchopulmonary Dysplasia

Conditions:   Bronchopulmonary Dysplasia (BPD);   Pulmonary Hypertension (PH)
Intervention:  
Sponsor:   Stanford University
Active, not recruiting - verified May 2015

Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Condition:   Primary Open Angle Glaucoma (POAG)
Interventions:   Device: iStent;   Device: iStent;   Device: iStent
Sponsor:   Glaukos Corporation
Recruiting - verified May 2015

Aliskiren vs Hydrochlorothiazide in Hypertensive Type II Diabetic Patients on Resistance Arteries

Conditions:   Hypertension;   Diabetes
Interventions:   Drug: Aliskiren vs. hydrochlorothiazide;   Drug: Hydrochlorothiazide
Sponsors:   Sir Mortimer B. Davis - Jewish General Hospital;   Novartis Pharmaceuticals
Withdrawn - verified May 2015

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost

Condition:   Open-angle Glaucoma
Interventions:   Device: iStent;   Drug: Travoprost
Sponsor:   Glaukos Corporation
Active, not recruiting - verified May 2015

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent Inject) or Travoprost

Condition:   Open-angle Glaucoma
Interventions:   Device: iStent inject;   Drug: Travoprost
Sponsor:   Glaukos Corporation
Recruiting - verified May 2015

Open-Angle Glaucoma Subjects With One Prior Trabeculectomy Treated Concurrently With One Suprachoroidal Stent and Two Trabecular Micro-bypass Stents

Condition:   Open-Angle Glaucoma
Intervention:   Device: iStent and iStent supra
Sponsor:   Glaukos Corporation
Active, not recruiting - verified May 2015

Open-angle Glaucoma Subjects on One Topical Hypotensive Medication Randomized to Treatment With One or Two Trabecular Micro-bypass Stents in Conjunction With Cataract Surgery

Condition:   Open-angle Glaucoma
Interventions:   Device: One iStent;   Device: Two iStent
Sponsor:   Glaukos Corporation
Active, not recruiting - verified May 2015

Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty

Condition:   Open-angle Glaucoma
Interventions:   Device: iStent;   Other: SLT
Sponsor:   Glaukos Corporation
Active, not recruiting - verified May 2015

Droxidopa / Pyridostigmine in Orthostatic Hypotension

Condition:   Orthostatic Hypotension
Interventions:   Drug: Droxidopa;   Drug: Pyridostigmine Bromide
Sponsor:   Mayo Clinic
Recruiting - verified May 2015

Meta-analyses of Fructose and Cardiometabolic Risk

Conditions:   Dyslipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Overweight;   Obesity;   Gout;   Hypertension;   Non-alcoholic Fatty Liver Disease;   Metabolic Syndrome;   Cardiovascular Disease
Intervention:   Other: Dietary fructose
Sponsors:   John Sievenpiper;   Canadian Institutes of Health Research  (CIHR);   Canada Research Chairs Endowment of the Federal Government of Canada;   Calorie Control Council
Active, not recruiting - verified May 2015

Effect of Arotinolol Hydrochloride on Cardiovascular Events in Hypertensive Haemodialysis Patients

Condition:   Chronic Kidney Disease
Interventions:   Drug: Arotinolol Hydrochloride;   Drug: Non arotinolol group
Sponsor:   Sumitomo Pharmaceutical (Suzhou) Co., Ltd.
Active, not recruiting - verified May 2011

MOVE OUT: A Partnership With Veterans Groups to Enhance Weight Management in VHA

Conditions:   Obesity;   Overweight + Diabetes Mellitus;   Overweight + Hypertension
Interventions:   Behavioral: MOVE OUT;   Behavioral: MOVE!
Sponsors:   Department of Veterans Affairs;   American Legion Department of Wisconsin;   Veterans of Foreign Wars of the United States, Department of Wisconsin;   All Saints Catholic Church;   St. Rita's Catholic Church;   Vets 76;   Dryhootch
Active, not recruiting - verified May 2015

Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia

Conditions:   Pre-Eclampsia;   Fetal Growth Retardation;   Premature Birth;   Placental Insufficiency
Interventions:   Drug: Acetylsalicylic Acid;   Drug: Acetylsalicylic Acid
Sponsor:   Centre Hospitalier Universitaire de Québec, CHU de Québec
Completed - verified July 2014

Evaluate Safety and Efficacy of Autologous Bone Marrow-derived Endothelial Progenitor Cells in Advanced Liver Cirrhosis

Condition:   Liver Cirrhosis
Intervention:   Other: Autologous bone marrow-derived endothelial progenitor cells
Sponsors:   Clinica Universidad de Navarra, Universidad de Navarra;   Foundation Ramon Areces;   Instituto de Salud Carlos III
Completed - verified May 2015

"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"

Conditions:   Sleep Apnea, Obstructive;   Hypoxia;   Hypercapnia;   Sleep Disorders;   Obesity;   Hypertension;   Coronary Artery Vasospasm;   Right Ventricular Overload;   Left Ventricular Function Systolic Dysfunction;   Ventricular Hypertrophy
Intervention:   Other: Clinically prescribed CPAP therapy
Sponsor:   University of Wisconsin, Madison
Completed - verified May 2015

Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril

Conditions:   Hypertension, Grade 1;   Hypertension Treatment;   N of 1 Study Design;   Hypertension
Interventions:   Drug: Lisinopril;   Drug: Hydrochlorothiazide
Sponsor:   Scripps Translational Science Institute
Completed - verified May 2015

Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Condition:   Primary Open Angle Glaucoma (POAG)
Interventions:   Device: iStent;   Device: iStent;   Device: iStent
Sponsor:   Glaukos Corporation
Active, not recruiting - verified May 2015

Prospective Evaluation of Open-angle Glaucoma Subjects on Two Topical Hypotensive Medication Treated With Two iStents

Condition:   Subjects With Primary Open-angle Glaucoma (POAG)
Intervention:   Device: iStents
Sponsor:   Glaukos Corporation
Active, not recruiting - verified May 2015

A Prospective Evaluation of Open-Angle Glaucoma Subjects on Two Topical Hypotensive Medications Treated With One Suprachoroidal Stent

Condition:   Subject With Primary Open-angle Glaucoma (POAG)
Intervention:   Device: iStent Supra Stent
Sponsor:   Glaukos Corporation
Active, not recruiting - verified May 2015

Prospective Evaluation of Open-Angle Glaucoma Subjects on One Topical Hypotensive Medication Treated With Two iStents

Condition:   Subjects With Primary Open-angle Glaucoma (POAG)
Intervention:   Device: iStent
Sponsor:   Glaukos Corporation
Active, not recruiting - verified May 2015

Invasive Revascularization or Not in Intermittent Claudication

Condition:   Intermittent Claudication
Interventions:   Procedure: INVASIVE (INV) treatment;   Other: Best medical treatment (BMT)
Sponsors:   Sahlgrenska University Hospital, Sweden;   Göteborg University
Active, not recruiting - verified May 2015

Cardiovascular Risk Factors, Lipid Metabolism and Oxidative Stress

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   University of Roma La Sapienza
Recruiting - verified May 2015

Long Term Use Of Xalacom In Patients Glaucoma Or Ocular Hypertension

Conditions:   Glaucoma;   Ocular Hypertension
Intervention:   Drug: Latanoprost-timolol maleate fixed combination ophthalmic solution
Sponsor:   Pfizer
Active, not recruiting - verified May 2015

The Use of a Community-based Organization to Change Lifestyle Characteristics Related to Non Communicable Diseases

Conditions:   Diabetes;   Hypertension;   Stroke;   Ischemic Heart Disease
Intervention:   Behavioral: lifestyle modification
Sponsor:   University of Kelaniya
Completed - verified May 2015

The Role of Endothelin in the Supine Hypertension of Autonomic Failure

Conditions:   Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions:   Drug: BQ123;   Drug: BQ123;   Drug: Bq123;   Drug: BQ123;   Drug: Saline
Sponsor:   Vanderbilt University
Recruiting - verified May 2015

Prazosin Treatment for Disruptive Agitation in Alzheimer's Disease

Condition:   Alzheimer's Disease
Interventions:   Drug: Prazosin;   Drug: Placebo
Sponsors:   Seattle Institute for Biomedical and Clinical Research;   National Institute on Aging (NIA);   VA Puget Sound Health Care System
Completed - verified May 2015

GTS400 Stent Implantation in Conjunction With Cataract Surgery in Subjects With Open-angle Glaucoma

Condition:   Glaucoma
Interventions:   Device: iStent Inject (GTS400);   Procedure: Cataract Surgery
Sponsor:   Glaukos Corporation
Completed - verified May 2015

BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified May 2015

A Prospective, Unmasked Evaluation of the iStent in Patients With Primary Open-Angle Glaucoma

Conditions:   Glaucoma;   Eye Diseases;   Glaucoma, Open-Angle
Intervention:   Device: iStent
Sponsor:   Glaukos Corporation
Completed - verified May 2015

Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG)

Conditions:   Eye Diseases;   Glaucoma, Open-Angle;   Glaucoma
Interventions:   Device: iStent;   Drug: latanoprost/timolol
Sponsor:   Glaukos Corporation
Completed - verified May 2015

Cyclooxygenase-2 Inhibitor for Adjuvant Anticancer Effect in Patients With Biliary-pancreas Cancer

Conditions:   Bile Duct Cancer;   Pancreatic Cancer
Intervention:   Drug: Cox2 inhibitor (Celecoxib)
Sponsors:   Seoul National University Hospital;   Seoul National University Bundang Hospital
Recruiting - verified May 2015

Effectiveness of Pulse-Based Foods Combined With Exercise for Improving Components of the Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Behavioral: Aerobic exercise training;   Dietary Supplement: pulse based diet
Sponsor:   University of Saskatchewan
Completed - verified May 2015

Prognostic Value of the Circadian Pattern of Ambulatory Blood Pressure for Cardiovascular Risk Assessment

Conditions:   Essential Hypertension;   Cardiovascular Disease;   Stroke;   Chronic Kidney Disease
Interventions:   Drug: Any antihypertensive medication alone or in combination;   Drug: Any antihypertensive medication alone or in combination;   Device: Ambulatory blood pressure monitoring
Sponsors:   University of Vigo;   Servicio Gallego de Salud
Recruiting - verified May 2015

Interval Training in Young Healthy Individuals

Conditions:   Healthy Subjects;   Exercise Test
Interventions:   Behavioral: High frequency training;   Behavioral: normal frequence training
Sponsor:   Norwegian University of Science and Technology
Completed - verified May 2015

Chronotherapy With Low-dose Aspirin for Primary Prevention

Condition:   Type 2 Diabetes
Interventions:   Drug: aspirin;   Drug: aspirin
Sponsor:   University of Vigo
Recruiting - verified May 2015

Renal Protective Effects of Renin Angiotensin System (RAS) Inhibitor in Peritoneal Dialysis Patients

Condition:   Renal Function Disorder
Interventions:   Drug: Benazepril;   Drug: Valsartan;   Drug: Benazepril+Valsartan;   Drug: Control
Sponsor:   Sun Yat-sen University
Completed - verified May 2015

Impact of Multiple Doses of BAY63-2521 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Patients With Interstitial Lung Disease (ILD) Associated Pulmonary Hypertension (PH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified May 2015

Trial of a Cardiac Rehabilitation Program Delivered Remotely Through the Internet

Condition:   Cardiovascular Disease
Intervention:   Behavioral: vCRP
Sponsors:   Simon Fraser University;   Heart and Stroke Foundation of Canada
Completed - verified May 2015

Long-term Extension Study of the SERAPHIN Study, to Assess the Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: ACT-064992
Sponsor:   Actelion
Active, not recruiting - verified May 2015

Promoting Healthy Weight With 'Stability Skills First'

Condition:   Obesity
Intervention:   Behavioral: Behavioral weight-loss/lifestyle interventions
Sponsors:   Stanford University;   National Cancer Institute (NCI)
Completed - verified May 2015

Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for HCC

Condition:   Hepatocellular Carcinoma
Intervention:   Procedure: Liver resection
Sponsor:   Seoul National University Hospital
Recruiting - verified May 2015

Complications in Hypertension and Obesity

Conditions:   Metabolic Syndrome;   Hypertension;   Obesity;   Dyslipidemia;   Hyperglycemia
Intervention:  
Sponsor:   Federal North-West Medical Research Centre
Recruiting - verified May 2015

Evaluation of Colecalciferol Substitution in Dialysis Patients

Conditions:   RENAL INSUFFICIENCY, CHRONIC;   Hyperparathyroidism, Secondary
Intervention:   Drug: Colecalciferol
Sponsor:   University Hospital, Saarland
Completed - verified May 2015

Losartan Versus Hydrochlorothiazide in Reversing Remodeling of Small Arteries in Pre-Hypertensive Pre-Diabetic Subjects

Conditions:   Pre-hypertension;   Pre-diabetes
Intervention:   Drug: losartan, hydrochlorothiazide
Sponsors:   Sir Mortimer B. Davis - Jewish General Hospital;   Merck Frosst Canada Ltd.
Terminated - verified May 2015

Community Partnership to Examine Racial and Ethnic Differences in Health Care for Hypertension and Diabetes

Conditions:   Hypertension;   Diabetes Mellitis
Interventions:   Behavioral: Medical Practice Improvement;   Behavioral: Patient Education and Support;   Other: Combination Intervention to Include Medical Practice Improvement and Patient Education and Support
Sponsors:   Harvard Medical School;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 2009

Evaluation of Patients With Liver Disease

Conditions:   Biliary Liver Cirrhosis,;   Hemochromatosis;   Hepatitis;   Hepatolenticular Degeneration;   Liver Disease
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified May 2015

Trial to Enhance Adherence to Multiple Guidelines

Conditions:   Asthma;   Cardiovascular Diseases;   Atherosclerosis;   Diabetes Mellitus;   Heart Diseases;   Hypertension;   Lung Diseases
Intervention:   Other: practice guideline adherence
Sponsors:   University of Medicine and Dentistry of New Jersey;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified May 2015

The Autonomic Nervous System and Obesity

Conditions:   OBESITY;   HYPERTENSION;   PURE AUTONOMIC FAILURE;   SHY-DRAGER SYNDROME
Interventions:   Drug: Trimethaphan;   Drug: Trimethaphan;   Drug: Pseudoephedrine
Sponsor:   Vanderbilt University
Recruiting - verified May 2015

Treatment of Orthostatic Hypotension in Autonomic Failure

Conditions:   Autonomic Failure;   Orthostatic Hypotension
Interventions:   Drug: Atomoxetine;   Drug: Acarbose;   Drug: Pyridostigmine Bromide;   Drug: Yohimbine;   Drug: Midodrine HCl;   Drug: placebo;   Drug: Modafinil;   Drug: Octreotide;   Other: water intake;   Drug: Diphenhydramine Hydrochloride;   Drug: Ranitidine HCL;   Drug: Tranylcypromine;   Drug: Ergotamine/ Caffeine;   Drug: Celecoxib;   Drug: Pseudoephedrine;   Drug: Methylphenidate;   Drug: Indomethacin;   Drug: Ibuprofen;   Drug: Oxymetazoline 0.05% nasal solution;   Dietary Supplement: Bovril;   Drug: Acetazolamide;   Drug: Rivastigmine tartrate;   Drug: Carbidopa/levodopa;   Device: Inflatable abdominal binder;   Device: inflatable abdominal binder (sham)
Sponsor:   Vanderbilt University
Recruiting - verified May 2015

Proteomics of Brain Trauma-associated Elevated Intracranial Pressure (ICP)

Conditions:   Brain Injuries, Traumatic;   Traumatic Brain Injury
Intervention:   Other: Blood/saliva samples for protein/molecular analysis
Sponsors:   The University of Texas Health Science Center, Houston;   TIRR/Mission Connect;   The Center for Clinical and Translational Sciences (CCTS) Clinical Research Unit at The University of Texas Health Science Center at Houston
Recruiting - verified May 2015

Get CardioSmart

You're Invited