High Blood Pressure

Clinical Trial Finder

Many patients with high blood pressure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Predictive Factors of Systolic Dysfunction in Non-complicated Hypertensive Patients

Condition:   Hypertension
Intervention:   Device: Cardiac echography
Sponsor:   University Hospital, Bordeaux
Not yet recruiting - verified July 2016

Evaluation of the Fixed-dose Combination of Irbesartan/Atorvastatin in Type 2 Diabetic Patients Diagnosed With Hyperlipidemia and Hypertension

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Irbesartan/atorvastatin fixed dose combination;   Drug: Irbesartan SR47436;   Drug: Atorvastatin
Sponsor:   Sanofi
Not yet recruiting - verified July 2016

The Northwest Coalition for Primary Care Practice Support

Conditions:   Cardiovascular Disease;   Essential Hypertension;   Nicotine Dependence;   Hyperlipidemia
Interventions:   Other: Coaching;   Other: Educational Outreach;   Other: Site Visits
Sponsors:   Group Health Cooperative;   University of Washington;   Oregon Health and Science University
Active, not recruiting - verified July 2016

TReatment Of Pulmonary HYpertension 1-US Study

Condition:   Pulmonary Arterial Hypertension
Intervention:   Device: Therapeutic Intra-Vascular UltraSound (TIVUS™) System
Sponsor:   SoniVie Ltd.
Not yet recruiting - verified July 2016

Nuts and Extra Virgin Olive Oil Pilot Study

Condition:   Hypertension
Interventions:   Dietary Supplement: Walnuts;   Dietary Supplement: Extra Virgin Olive Oil
Sponsors:   Wake Forest School of Medicine;   California Walnut Growers Association;   C.H.O. American, Natural and Organic Olive Oil Producer Association
Completed - verified July 2016

Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453

Conditions:   Hypertension;   Chronic Heart Failure
Interventions:   Drug: BIA 5-453;   Drug: Placebo
Sponsor:   Bial - Portela C S.A.
Completed - verified July 2016

Moderato System: A Double-Blind Randomized Trial

Conditions:   Hypertension Resistant to Conventional Therapy;   Bradycardia;   Atrioventricular Block
Interventions:   Device: BackBeat-PHC ON;   Device: BackBeat-PHC OFF
Sponsor:   BackBeat Medical Inc
Recruiting - verified July 2016

Targeting Right Ventricle in Pulmonary Hypertension Gilead

Condition:   Pulmonary Hypertension
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsors:   University of Pennsylvania;   Brigham and Women's Hospital;   University of Maryland;   Gilead Sciences
Recruiting - verified July 2016

Effect of a Continuous Glucose Monitoring on Maternal and Neonatal Outcomes in Gestational Diabetes Mellitus

Condition:   GDM
Interventions:   Device: FreeStyle sensors.;   Device: Glucometer
Sponsor:   Tel-Aviv Sourasky Medical Center
Not yet recruiting - verified July 2016

Controlling and Lowering Blood Pressure With the MobiusHD™

Condition:   Hypertension
Intervention:   Device: MobiusHD™
Sponsor:   Vascular Dynamics, Inc.
Recruiting - verified July 2016

Safety Study of RMJH-111b to Treat Essential Hypertension

Condition:   Essential Hypertension
Interventions:   Drug: RMJH-111b;   Drug: Placebo
Sponsor:   RMJ Holdings, LLC
Completed - verified July 2016

Aqueous Dynamics and Glaucoma Surgeries

Conditions:   Glaucoma;   Ocular Hypertension
Interventions:   Device: HiFU;   Device: Baerveldt implant;   Device: Ahmed implant;   Device: STARflo;   Device: Hydrus Microstent implant;   Device: iStent implant;   Device: Kahook Dual Blade
Sponsor:   Guy's and St Thomas' NHS Foundation Trust
Recruiting - verified July 2016

Effects of Compression in Mixed Ulcers.

Condition:   Ulcer
Intervention:   Other: No intervention
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Completed - verified July 2016

Diabetes Complication Control in Community Clinics (D4C) Trial

Conditions:   Diabetes;   Hypertension;   Dyslipidemia;   Cardiovascular Disease
Intervention:   Other: Protocol-based integrated care
Sponsors:   Tulane University Health Sciences Center;   Xiamen Diabetes Institute, Xiamen University, Xiamen, China
Not yet recruiting - verified July 2016

Analysis of Translaminar Pressure Gradient Using Noninvasive Cerebrospinal Fluid Pressure Monitoring

Condition:   Glaucoma
Intervention:   Device: Two-Dimensional Transcranial Doppler
Sponsor:   University of Miami
Enrolling by invitation - verified July 2016

Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery

Conditions:   Glaucoma;   Cataract
Interventions:   Procedure: Femtolaser surgery;   Procedure: Phacoemulsification
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified July 2016

Magnesium Sulfate in Obese Preeclamptics

Condition:   Preeclampsia
Interventions:   Drug: Magnesium sulfate 4g loading dose, 1g/hr infusion;   Drug: Magnesium sulfate 6g loading dose, 2g/hr infusion
Sponsor:   Oregon Health and Science University
Enrolling by invitation - verified July 2016

Abdominal Compartment Syndrome : Diagnostic and Prognostic Value of CT Findings - a Prospective Study

Conditions:   Intra-Abdominal Hypertension;   Abdominal Compartment Syndrome
Intervention:  
Sponsor:   Centre Hospitalier Universitaire de Besancon
Not yet recruiting - verified July 2016

Capsaicin Effect on Cytokines Profile in Dyslipidemia

Conditions:   Dyslipidemia;   Overweight or Obesity
Interventions:   Drug: Capsaicin;   Drug: Magnesia calcinada
Sponsors:   University of Guadalajara;   PhD. Teresa Arcelia Garcia Cobian;   LN. Jessica Lucia Barajas Vega
Not yet recruiting - verified July 2016

Non-interventional, Postauthorization Safety Study of Ventavis for Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Ventavis (Iloprost, BAYQ6256)
Sponsor:   Bayer
Not yet recruiting - verified July 2016

Validation of Pulsewave Blood Pressure Monitor in Hypertensive and Normotensive Pregnant and Postpartum Women

Condition:   Hypertension
Intervention:   Device: Pulsewave oscillometric wrist cuff blood pressure monitor
Sponsor:   University of Arkansas
Withdrawn - verified July 2016

Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension

Condition:   Hypertension Resistant to Conventional Therapy
Interventions:   Drug: Spironolactone;   Drug: Furosemide,;   Drug: Amiloride;   Drug: Ramipril;   Drug: Bisoprolol
Sponsor:   Sao Jose do Rio Preto University
Recruiting - verified July 2016

Diet Intervention for Hypertension: Adaptation and Dissemination to Native Communities

Condition:   Hypertension
Interventions:   Behavioral: Limited Groceries + Dietician Sessions;   Behavioral: Groceries + Brochure
Sponsors:   Washington State University;   University of Oklahoma
Not yet recruiting - verified June 2016

Sildenafil Administration to Treat Neonatal Encephalopathy

Condition:   Neonatal Encephalopathy
Interventions:   Drug: Sildenafil;   Drug: Ora-Blend
Sponsor:   McGill University Health Center
Recruiting - verified July 2016

Increasing Risk Perception of Physical Activity Using Patient-targeted Feedback.

Conditions:   Hypertension;   Coronary Disease;   Cardiac Diseases
Interventions:   Behavioral: Patient-targeted individual physical-activity-feedback;   Device: Pedometer
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Not yet recruiting - verified July 2016

Naloxegol Health Outcomes PASS

Condition:   Opioid Induced Constipation
Interventions:   Drug: naloxegol;   Drug: non-PAMORA laxative
Sponsor:   AstraZeneca
Not yet recruiting - verified July 2016

Chlorthalidone in Chronic Kidney Disease

Conditions:   Renal Insufficiency, Chronic;   Hypertension
Interventions:   Drug: Chlorthalidone;   Drug: Placebo
Sponsors:   Indiana University;   University of Alabama at Birmingham
Recruiting - verified July 2016

Clinical Profile of Patients With Pulmonary Hypertension Due to Lung Diseases ( Single Center Experience)

Condition:   Pulmonary Hypertension
Intervention:  
Sponsor:   Cairo University
Recruiting - verified July 2016

Pulmonary Hemodynamics in Patients With Severe Emphysema Pre and Post BLVR

Conditions:   Pulmonary Hypertension;   Chronic Obstructive Lung Disease
Intervention:  
Sponsor:   Cairo University
Recruiting - verified July 2016

Innovative Multigenerational Household Intervention to Reduce Stroke and CVD

Conditions:   Stroke;   Cardiovascular Disease
Intervention:   Behavioral: Motivational Interviewing
Sponsor:   Washington State University
Recruiting - verified July 2016

Study of Supplement's Antioxidant Properties That Contains Natural Extracts

Condition:   Healthy
Interventions:   Dietary Supplement: Mind Master;   Dietary Supplement: Placebo
Sponsor:   Harokopio University
Active, not recruiting - verified July 2016

Prevalence of Pulmonary Arterial Hypertension in Patients With Connective Tissue Diseases in Egyptian Patients

Conditions:   Connective Tissue Diseases;   Pulmonary Hypertension
Intervention:  
Sponsor:   Cairo University
Recruiting - verified July 2016

Efficacy of Aspirin and L-arginine in High Risk Preeclamptic

Condition:   High Risk Pregnancy
Interventions:   Drug: L-arginine;   Drug: Placebo (for L-arginine);   Drug: acetylsalicylic acid
Sponsors:   University of Guadalajara;   PhD Ernesto Javier Ramírez Lizardo;   PhD Sylvia Elena Totsuka Sutto;   PhD Fernando Grover Páez;   MD Diego Hernández Molina
Not yet recruiting - verified July 2016

Open-label, Single Arm Trial of BI 695502 in Patients With Previously Untreated Metastatic Colorectal Cancer

Condition:   Colorectal Neoplasms
Interventions:   Drug: BI 695502;   Drug: chemotherapy
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Clinical Outcomes of Preoperative and Postoperative Rehabilitation in the Patients With HBP Malignancy

Conditions:   Hepatic Neoplasms;   Biliary Tract Neoplasms;   Pancreatic Neoplasms
Interventions:   Behavioral: Perioperative rehabilitation program;   Behavioral: Conventional
Sponsor:   Asan Medical Center
Not yet recruiting - verified July 2016

Documentation of Heart Failure in a Gulf Registry

Condition:   Heart Failure
Intervention:  
Sponsor:   Gulf Heart Association
Not yet recruiting - verified July 2016

A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension.

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Adempas (Riociguat, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified July 2016

Tele-Health Electronic Monitoring to Reduce Post Discharge Complications and Surgical Site Infections

Condition:   Peripheral Vascular Disease
Intervention:   Other: Tele-Health Electronic Monitoring (THEM)
Sponsors:   CAMC Health System;   WVCTSI
Enrolling by invitation - verified July 2016

The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure

Conditions:   Glaucoma, Open-angle;   Hypertension, Ocular
Intervention:   Drug: Pilocarpine
Sponsor:   University of Colorado, Denver
Not yet recruiting - verified July 2016

N-of-1 Trials for Blood Pressure Medications in Adults

Conditions:   Hypertension;   High Blood Pressure
Interventions:   Drug: Losartan;   Drug: Amlodipine;   Drug: Hydrochlorothiazide
Sponsor:   Columbia University
Active, not recruiting - verified July 2016

Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Nitric Oxide
Sponsor:   Allegheny Singer Research Institute
Recruiting - verified July 2016

A Cohort Study of Operationally Tolerant Allograft Recipients

Conditions:   Kidney Transplant;   Liver Transplant
Intervention:   Procedure: Blood Draw
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Immune Tolerance Network (ITN)
Recruiting - verified July 2016

Trial of Monthly Versus Bi-weekly Endoscopic Variceal Ligation for the Prevention of Esophageal Variceal Rebleeding

Condition:   Esophageal and Gastric Varices
Interventions:   Procedure: monthly Endoscopic Variceal Ligation (EVL);   Procedure: bi-weekly Endoscopic Variceal Ligation (EVL)
Sponsor:   West China Hospital
Recruiting - verified July 2016

Evaluation of a New Thermostable Formulation of FLOLAN in Japanese Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: FLOLAN injection with currently marketed diluent;   Drug: FLOLAN injection with reformulated diluent
Sponsor:   GlaxoSmithKline
Active, not recruiting - verified July 2016

A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects

Condition:   Hypertension, Pulmonary
Interventions:   Drug: FDC (ambrisentan 10 mg-tadalafil 40 mg) single dose;   Drug: Reference (ambrisentan 10 mg + tadalafil 40 mg given concurrently)
Sponsors:   GlaxoSmithKline;   Covance Harrogate;   Hammersmith Medicines Research
Recruiting - verified July 2016

Phenolic-rich Oats for Gut-bacteria Relief and Artery Improvement

Condition:   Healthy
Interventions:   Other: Oat;   Other: Control
Sponsors:   University of Reading;   Biotechnology and Biological Sciences Research Council;   Rothamsted Research;   PepsiCo Global R&D;   University of Roehampton
Recruiting - verified July 2016

The Effect of On-Line Hemodiafiltration Versus High Flux Hemodialysis on Hemodynamic Parameters in Patients With Intra-Dialytic Hypotension

Condition:   Intradialytic Hypotension
Intervention:   Device: NICaS
Sponsor:   Western Galilee Hospital-Nahariya
Not yet recruiting - verified March 2016

An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE

Conditions:   Pulmonary Hypertension;   Interstitial Lung Disease;   Combined Pulmonary Fibrosis and Emphysema
Intervention:   Drug: Inhaled Treprostinil
Sponsor:   United Therapeutics
Enrolling by invitation - verified July 2016

Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE

Conditions:   Pulmonary Hypertension;   Interstitial Lung Disease;   Combined Pulmonary Fibrosis and Emphysema
Interventions:   Drug: Inhaled Treprostinil;   Drug: Placebo
Sponsor:   United Therapeutics
Recruiting - verified July 2016

Effect of a Specific Phenolic Compound on Blood Pressure

Conditions:   Cardiovascular Risk Factors;   Blood Pressure
Interventions:   Dietary Supplement: placebo;   Dietary Supplement: phenolic compound
Sponsors:   Technological Centre of Nutrition and Health, Spain;   University Rovira i Virgili;   Hospital Universitari Sant Joan de Reus;   Fundació Catalana per a la Recerca i la Innovació (FCRI)
Recruiting - verified July 2016

Air Pollution and Cardiometabolic Study

Condition:   Hypertension
Intervention:  
Sponsor:   WeiHuang
Completed - verified November 2015

Assessing the Usability and Clinical Utility of the Congo Red Dot Test: A Survey

Condition:   Preeclampsia
Intervention:   Device: Congo Red Dot Test
Sponsors:   Gynuity Health Projects;   Nationwide Children's Hospital
Not yet recruiting - verified July 2016

Assessing the Usability and Clinical Utility of the Congo Red Dot Test: A Case-control Study

Condition:   Preeclampsia
Intervention:   Device: Congo Red Dot Test
Sponsors:   Gynuity Health Projects;   Nationwide Children's Hospital
Not yet recruiting - verified July 2016

ABI-009, an mTOR Inhibitor, for Patients With Severe Pulmonary Arterial Hypertension

Condition:   Pulmonary Hypertension
Intervention:   Drug: ABI-009, nab-rapamycin, albumin-bound rapamycin
Sponsor:   Aadi, LLC
Not yet recruiting - verified July 2016

CKD-330 Phase 3 Trial in Amlodipine Non-responder

Condition:   Hypertension
Interventions:   Drug: CKD-330 16/5mg;   Drug: Amlodipine 5mg Placebo;   Drug: CKD-330 16/5mg Placebo;   Drug: Amlodipine 5mg
Sponsor:   Chong Kun Dang Pharmaceutical
Active, not recruiting - verified July 2016

Peripheral Chemoreflex/Arterial Baroreflex Interaction in Patients With Electrical Carotid Sinus Stimulation

Condition:   Hypertension, Resistant to Conventional Therapy
Interventions:   Other: Hypoxia without dopamine;   Other: Hypoxia with dopamine;   Other: Hyperoxia without dopamine;   Other: Hyperoxia with dopamine
Sponsors:   Hannover Medical School;   Charite University, Berlin, Germany;   Vanderbilt University School of Medicine;   Mayo Clinic;   University of Bristol
Recruiting - verified October 2015

Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular Hypertension

Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension
Intervention:   Drug: bimatoprost 0.03% plus timolol 0.5%
Sponsor:   Allergan
Recruiting - verified July 2016

iPhone App Compared to Standard RR-measurement

Conditions:   Hypertension;   Blood Pressure
Interventions:   Device: cuff device (Omron HBP-1300-E Pro);   Device: iPhone 4s
Sponsors:   Jens Eckstein;   Preventicus GmbH
Active, not recruiting - verified July 2016

H-36731: Finasteride in Management of Elevated Red Blood Cells

Condition:   ERYTHROCYTOSIS
Intervention:   Drug: Finasteride
Sponsor:   Baylor College of Medicine
Withdrawn - verified July 2016

Egypt Hypertension Study

Condition:   Different Classes of the Antihypertensive Treatment.
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2016

Multi-micronutrient Supplementation During Peri-conception and Congenital Heart Disease

Condition:   Congenital Heart Disease
Interventions:   Dietary Supplement: Vitamin B Complex and Folic Acid;   Dietary Supplement: Iron and Folic Acid;   Dietary Supplement: Folic Acid
Sponsor:   Health Science Center of Xi’an Jiaotong University
Recruiting - verified July 2016

Electronic Activity Level Monitoring Pilot in Pulmonary Hypertension

Conditions:   Pulmonary Hypertension;   Hypertension, Pulmonary
Intervention:   Other: Correlation assessment
Sponsor:   Bayer
Active, not recruiting - verified July 2016

Prevalence of Resistant Hypertension With DOT

Condition:   Hypertension
Intervention:   Procedure: Direct Observed Therapy test
Sponsor:   Ottawa Hospital Research Institute
Recruiting - verified July 2016

Exercise and Pharmacotherapy for Anxiety in Cardiac Patients

Conditions:   Anxiety;   Cardiovascular Disease
Interventions:   Drug: Lexapro;   Drug: Placebo;   Behavioral: Supervised Aerboic Exercise
Sponsor:   Duke University
Recruiting - verified July 2016

A Phase 3b Study of Erythropoietin Drugs Using a Specified Dosing Algorithm in Patients With Chronic Kidney Disease on Hemodialysis

Condition:   Chronic Kidney Disease (CKD)
Interventions:   Drug: Epoetin Hospira Arm;   Other: Standard of Care Arm;   Drug: IV Iron
Sponsors:   Pfizer;   Hospira, is now a wholly owned subsidiary of Pfizer
Active, not recruiting - verified July 2016

Azilsartan Medoxomil in the Treatment of Essential Hypertension and Type 2 Diabetes in Asia

Conditions:   Essential Hypertension;   Type 2 Diabetes Mellitus
Intervention:   Drug: Azilsartan Medoxomil
Sponsor:   Takeda
Recruiting - verified July 2016

IRIS Registry: Intelligent Research in Sight Registry

Condition:   Eye Diseases
Intervention:   Procedure: Ophthalmology
Sponsor:   American Academy of Ophthalmology
Recruiting - verified July 2016

Effect of Rosuvastatin on Coronary Flow Reserve in Hypertensive Patients With Cardiovascular Risk

Condition:   Hypertension
Interventions:   Drug: Rosuvastatin;   Behavioral: Life style modification
Sponsors:   Asan Medical Center;   Dong-A ST Co., Ltd.
Recruiting - verified July 2016

8mm-TIPS Versus Endoscopic Variceal Ligation (EVL) Plus Propranolol for Prevention of Variceal Rebleeding

Condition:   Portal Hypertension
Interventions:   Procedure: 8mm-TIPS;   Procedure: Endoscopic variceal ligation;   Drug: Propranolol;   Device: 8mm ePTFE-covered stent
Sponsor:   West China Hospital
Recruiting - verified July 2016

Health Evaluation in African Americans Using RAS Therapy

Condition:   Alzheimer's Disease
Interventions:   Drug: Telmisartan 20mg;   Drug: Telmisartan 40mg;   Drug: Placebo
Sponsor:   Emory University
Recruiting - verified July 2016

Real Evidence of Anticoagulation Treatment in Non-valvular Atrial Fibrillation in Germany, UK and France: REACT-AF2

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Bristol-Myers Squibb;   IMS Health;   Oxon Epidemiology
Active, not recruiting - verified July 2016

Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosis

Condition:   Hypertension, Portal
Interventions:   Drug: GR-MD-02;   Drug: Placebo
Sponsors:   Galectin Therapeutics Inc.;   Brooke Army Medical Center, Stephen A. Harrison, MD;   Indiana University, Naga Chalasani, MD
Active, not recruiting - verified March 2016

Acute Gastric Variceal Bleeding: Endoscopic Treatment Versus BRTO

Condition:   Gastric Varices
Interventions:   Procedure: Balloon-occluded retrograde transvenous obliteration;   Procedure: Endoscopic cyanoacrylate injection;   Drug: N-butyl-2-cyanoacrylate;   Drug: Lauromacrogol
Sponsor:   West China Hospital
Recruiting - verified July 2016

Primary Prophylaxis of Gastric Variceal Bleed

Condition:   Gastric Varices
Interventions:   Procedure: Balloon-occluded retrograde transvenous obliteration;   Procedure: Endoscopic cyanoacrylate injection;   Drug: N-butyl-2-cyanoacrylate;   Drug: Lauromacrogol
Sponsor:   West China Hospital
Recruiting - verified July 2016

Secondary Prophylaxis of Gastric Variceal Bleed

Condition:   Gastric Varices
Interventions:   Procedure: Balloon-occluded retrograde transvenous obliteration;   Procedure: Endoscopic cyanoacrylate injection;   Drug: N-butyl-2-cyanoacrylate;   Drug: Lauromacrogol
Sponsor:   West China Hospital
Recruiting - verified July 2016

SPYRAL HTN-ON MED Study

Conditions:   Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions:   Device: Symplicity Spyral™ multi-electrode renal denervation system;   Procedure: Sham Procedure
Sponsor:   Medtronic Vascular
Recruiting - verified July 2016

SPYRAL HTN-OFF MED Study

Conditions:   Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions:   Device: Symplicity Spyral™ multi-electrode renal denervation system;   Procedure: Sham Procedure
Sponsor:   Medtronic Vascular
Recruiting - verified July 2016

Effect of Sildenafil for Sustained PAH After MV Surgery (SUPERIOR Trial)

Conditions:   Hypertension, Pulmonary;   Diseases of Mitral Valve
Interventions:   Drug: Sildenafil;   Drug: Placebo
Sponsor:   Asan Medical Center
Active, not recruiting - verified July 2016

Study Comparing Lutonix AV Drug Coated Balloon vs Standard Balloon for Treatment of Dysfunctional AV Fistulae

Condition:   Arteriovenous Fistula
Interventions:   Device: Lutonix DCB;   Device: Standard Balloon Angioplasty Catheter
Sponsor:   C. R. Bard
Active, not recruiting - verified July 2016

Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension

Condition:   Hypertension
Interventions:   Drug: Trimethaphan;   Drug: Nitroglycerin
Sponsor:   Vanderbilt University
Recruiting - verified July 2016

Blood Pressure Control of Nifedipine GITS 60mg Treatment in Chinese Hypertensive Subjects Uncontrolled on Starting-dose Mono-therapyo-therapy.

Condition:   Hypertension
Intervention:   Drug: Nifedipine(Adalat_BAY1040)
Sponsor:   Bayer
Active, not recruiting - verified July 2016

Diagnosis and Prediction of Pre-Eclampsia by Using Congo Red Dot Test in Bangladesh and Mexico

Condition:   Preeclampsia
Intervention:   Device: Congo Red Dot Test
Sponsors:   Gynuity Health Projects;   Nationwide Children's Hospital
Recruiting - verified July 2016

Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: Brinzolamide 10 mg/mL / Brimonidine 2 mg/mL fixed combination eye drops, suspension;   Drug: Brinzolamide 10 mg/mL eye drops, suspension;   Drug: Brimonidine 2 mg/mL eye drops, solution;   Drug: Vehicle
Sponsor:   Alcon Research
Active, not recruiting - verified July 2016

Weight Loss Referral for Healthier Survivorship in Obese Stage I-II Endometrial Cancer Survivors or Atypical Hyperplasia

Conditions:   Complex Endometrial Hyperplasia With Atypia;   Stage IA Uterine Corpus Cancer;   Stage IB Uterine Corpus Cancer;   Stage II Uterine Corpus Cancer
Interventions:   Behavioral: Weight Loss Specialist;   Other: Quality-of-Life Assessment;   Other: Medical Chart Review
Sponsors:   Case Comprehensive Cancer Center;   National Cancer Institute (NCI)
Active, not recruiting - verified July 2016

Online CBT-I for High Blood Pressure

Conditions:   Hypertension;   Prehypertension;   Insomnia
Interventions:   Behavioral: Cognitive Behavioral Therapy;   Behavioral: Healthy Sleep Habits
Sponsors:   Emory University;   American Heart Association
Active, not recruiting - verified July 2016

Dietary Counseling to Reduce Salt Intake in Patients With High Blood Pressure

Condition:   Hypertension
Interventions:   Behavioral: Dietary Counseling;   Other: Control: Standard Care
Sponsors:   Ottawa Hospital Research Institute;   The Ottawa Hospital Academic Medical Association
Recruiting - verified July 2016

Whole Muscle Exercise Training (WHOLEi+12) in Pulmonary Hypertension

Condition:   Exercise Therapy
Intervention:   Other: exercise
Sponsor:   Universidad Europea de Madrid
Completed - verified July 2016

Pulmonary Artery Denervation for Treatment of Pulmonary Arterial Hypertension

Condition:   Life Change Events
Interventions:   Procedure: Pulmonary Arterial Denervation (PADN);   Drug: Sildenafil;   Drug: Bosentan;   Drug: Prostacyclin
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Active, not recruiting - verified July 2016

A Phase III Long-term Study of TAK-536TCH in Patients With Essential Hypertension

Condition:   Essential Hypertension
Intervention:   Drug: TAK-536TCH tablet, TAK-536CCB tablet, and HCTZ 12.5 mg tablet
Sponsor:   Takeda
Completed - verified July 2016

Safety and Performance Study of the Moderato System

Conditions:   Hypertension Resistant to Conventional Therapy;   Bradycardia;   Atrioventricular Block
Intervention:   Device: The Moderato System
Sponsor:   BackBeat Medical Inc
Active, not recruiting - verified July 2016

Effects of Different Aerobic Exercise Programs With Nutritional Interventions in Hypertensive and Overweight People

Conditions:   Hypertension;   Overweight;   Sedentary
Interventions:   Behavioral: DIET;   Behavioral: DIET & MODERATE CONTINUOUS TRAINING;   Behavioral: DIET & HIGH VOLUME HIIT;   Behavioral: DIET & LOW VOLUME HIIT
Sponsors:   Basque Country University;   IMQ-Igualatorio Médico Quirúrgico, Vitoria-Gasteiz (Araba/Álava);   Servicios Tecnológicos de Tecnalia;   Hospital Comarcal Santiago Apostol, Miranda de Ebro (Burgos)
Active, not recruiting - verified July 2016

Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years

Condition:   PAH
Intervention:   Drug: oral treprostinil
Sponsor:   United Therapeutics
Recruiting - verified July 2016

Phase III Trial BI 695502 Plus Chemotherapy vs. Avastin® Plus Chemotherapy in Patients With Lung Cancer

Condition:   Carcinoma, Non-Small-Cell Lung
Interventions:   Drug: Chemotherapy;   Drug: BI 695502;   Drug: bevacizumab;   Drug: Chemotherapy
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Safety and Efficacy of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension

Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension
Interventions:   Drug: Bimatoprost sustained-release;   Other: Sham;   Drug: Timolol;   Drug: Timolol Vehicle (placebo)
Sponsor:   Allergan
Recruiting - verified July 2016

Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-angle Glaucoma or Ocular Hypertension

Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension
Interventions:   Drug: Bimatoprost sustained-release;   Other: Sham;   Drug: Timolol;   Drug: Timolol Vehicle (placebo)
Sponsor:   Allergan
Recruiting - verified July 2016

Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection

Conditions:   Cirrhosis;   Hypertension;   Status;Splenectomy;   Venous Thrombosis
Interventions:   Drug: Warfarin;   Drug: Dipyridamole;   Drug: Aspirin;   Drug: Low Molecular Weight Heparin
Sponsor:   Yangzhou University
Recruiting - verified July 2016

Study of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Conditions:   Ocular Hypertension.;   Glaucoma
Interventions:   Drug: Netarsudil (AR-13324) Ophthalmic Solution q.d.;   Drug: Netarsudil (AR-13324) Ophthalmic Solution b.i.d.;   Drug: Timolol maleate Ophthalmic Solution b.i.d.
Sponsor:   Aerie Pharmaceuticals
Active, not recruiting - verified July 2016

An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension

Condition:   Hypertension
Interventions:   Drug: Azilsartan Medoxomil;   Drug: Losartan;   Drug: Placebo for Azilsartan Medoxomil;   Drug: Placebo for Losartan
Sponsor:   Arbor Pharmaceuticals, Inc.
Recruiting - verified July 2016

Tissue Sodium in Pre-hypertensive Patients

Condition:   Hypertension
Interventions:   Drug: Spironolactone;   Drug: Chlorthalidone;   Dietary Supplement: Diet;   Drug: Placebo
Sponsors:   Vanderbilt University;   American Heart Association
Recruiting - verified July 2016

Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy

Conditions:   Cirrhosis;   Hypertension;   Venous Thrombosis;   Status; Splenectomy
Interventions:   Drug: Warfarin;   Drug: Dipyridamole;   Drug: Aspirin;   Drug: Low Molecular Weight Heparin
Sponsor:   Yangzhou University
Recruiting - verified July 2016

Biomarker Guided Therapies in Stage A/B Heart Failure

Conditions:   Hypertension;   Diabetes;   Cardiovascular Disease
Interventions:   Drug: Carvedilol;   Drug: Spironolactone
Sponsors:   VA Office of Research and Development;   Baylor College of Medicine
Recruiting - verified July 2016

Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery

Conditions:   Obesity;   Sleep Apnea;   Diabetes;   Hypertension
Interventions:   Drug: Dexmedetomidine;   Drug: Morphine
Sponsor:   American University of Beirut Medical Center
Completed - verified January 2016

AOP2014 in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.

Condition:   Polycythemia Vera
Intervention:   Drug: Pegylated-Proline-interferon alpha-2b
Sponsors:   AOP Orphan Pharmaceuticals AG;   PharmaEssentia (Co-Sponsor for USA)
Active, not recruiting - verified July 2016

Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension

Conditions:   Ocular Hypertension;   Open-angle Glaucoma
Interventions:   Drug: Netarsudil (AR-13324) Ophthalmic Solution;   Drug: Timolol maleate Ophthalmic Solution
Sponsor:   Aerie Pharmaceuticals
Completed - verified July 2016

Testing Tissue Sodium Stores in CAPD Patients—Aims 1 & 2

Condition:   End Stage Renal Disease
Intervention:  
Sponsors:   Vanderbilt University;   Baxter Healthcare Corporation
Recruiting - verified July 2016

24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension

Conditions:   Diabetes Mellitus, Type 2;   Hypertension
Interventions:   Drug: Empagliflizon low dose;   Drug: placebo;   Drug: Empagliflizon high dose
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified July 2016

Regorafenib as Single Agent in Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab

Conditions:   Colorectal Neoplasms;   Metastatic Disease
Intervention:   Drug: Regorafenib
Sponsors:   Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD);   Bayer
Terminated - verified July 2016

Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass

Conditions:   Ischemia/Reperfusion Injury After Neonatal Cardiac Surgery;   Inflammatory Reaction After Neonatal Cardiac Surgery
Interventions:   Drug: Inhaled NO;   Drug: placebo
Sponsors:   Chawki Elzein;   Mallinckrodt
Recruiting - verified July 2016

Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (ADEMPAS, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified July 2016

EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat(BAY63-2521)
Sponsor:   Bayer
Recruiting - verified July 2016

Pilot Study to Evaluate Right Ventricular Function With Riociguat in CTEPH

Condition:   Chronic Thromboembolic Pulmonary Hypertension
Intervention:   Radiation: Cardiac PET imaging using F-18-FDG, N-13 ammonia( NH3)
Sponsors:   Ottawa Heart Institute Research Corporation;   Bayer
Active, not recruiting - verified May 2016

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Condition:   Carotid Stenosis
Interventions:   Procedure: Carotid endarterectomy;   Device: Carotid stenting
Sponsors:   Thomas G. Brott, M.D.;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified July 2016

Study of Efficacy and Safety of CVAA489 in Hypertensive Patients

Condition:   Essential Hypertension
Intervention:   Drug: amlodipine/valsartan
Sponsor:   Novartis Pharmaceuticals
Completed - verified July 2016

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)

Conditions:   Hypertension;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified July 2016

Effects of Oral Sildenafil on Mortality in Adults With PAH

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: sildenafil citrate;   Drug: sildenafil citrate;   Drug: sildenafil citrate
Sponsor:   Pfizer
Recruiting - verified July 2016

Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT

Conditions:   Pulmonary Arterial Hypertension;   Pulmonary Hypertension
Interventions:   Drug: Bardoxolone methyl;   Drug: Placebo
Sponsor:   Reata Pharmaceuticals, Inc.
Recruiting - verified July 2016

World Trade Center Adolescent Health Study

Conditions:   Asthma;   Hypertension;   Cardiovascular Risk Factor;   Insulin Resistance;   Stress Disorders, Post-Traumatic;   Exposure to Toxic Dust
Intervention:  
Sponsor:   New York University School of Medicine
Recruiting - verified July 2016

AqueSys XEN 45 Glaucoma Implant in Refractory Glaucoma

Conditions:   Glaucoma;   Glaucoma, Open Angle
Intervention:   Device: AqueSys XEN 45 Glaucoma Implant
Sponsors:   AqueSys, Inc.;   Allergan
Active, not recruiting - verified July 2016

Renal Denervation for Uncontrolled Hypertension

Condition:   Hypertension
Intervention:   Device: Renal Denervation
Sponsor:   Baker IDI Heart and Diabetes Institute
Withdrawn - verified July 2016

Improving Health Outcomes: Blood Pressure

Condition:   Hypertension
Intervention:  
Sponsors:   American Medical Association;   Johns Hopkins University
Active, not recruiting - verified July 2016

Observational Study of the EnligHTN Renal Denervation System in Patients With Uncontrolled Hypertension

Condition:   Uncontrolled Hypertension
Intervention:   Device: EnligHTN™ Renal Denervation System
Sponsor:   St. Jude Medical
Recruiting - verified July 2016

EnligHTN German Observational Study

Condition:   Uncontrolled Hypertension
Intervention:  
Sponsor:   St. Jude Medical
Recruiting - verified July 2016

Evaluation of the XEN Implant in Moderate POAG Subjects

Condition:   Primary Open Angle Glaucoma
Interventions:   Device: XEN Gel Stent;   Device: XEN Gel Stent with cataract surgery
Sponsor:   AqueSys, Inc.
Active, not recruiting - verified July 2016

Remodulin as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn

Condition:   Persistent Pulmonary Hypertension of the Newborn
Interventions:   Drug: IV Remodulin;   Drug: Placebo
Sponsor:   United Therapeutics
Recruiting - verified July 2016

Non-interventional Study on Compliance of Inhaled Treatment With Ventavis in Patient With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Iloprost (Ventavis, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified July 2016

Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy

Conditions:   Hypertension in Pregnancy;   Preeclampsia
Interventions:   Drug: Nifedipine;   Drug: Labetalol;   Drug: Methyldopa
Sponsors:   Gynuity Health Projects;   Government Medical College, Nagpur;   Daga Memorial Women's Hospital, Nagpur, India;   University of British Columbia;   Bill and Melinda Gates Foundation
Recruiting - verified July 2016

A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurrence

Conditions:   Persistent Atrial Fibrillation;   Paroxysmal Atrial Fibrillation;   Hypertension;   Renal Denervation;   Cardiac Ablation
Interventions:   Device: Renal Artery Ablation Catheter;   Device: Cardiac Ablation
Sponsor:   St. Jude Medical
Recruiting - verified July 2016

Effect of Antihypertensive Agents Over Sleep Apnea

Conditions:   Hypertension;   Obstructive Sleep Apnea
Interventions:   Drug: Diuretics;   Drug: Calcium Channel Blockers
Sponsor:   Hospital de Clinicas de Porto Alegre
Completed - verified July 2016

Non-interventional Multi-center Study on Patients Under Routine Treatment of Pulmonary Arterial Hypertension (PAH) With Inhaled Iloprost Using I-Neb as a Device for Inhalation

Condition:   Pulmonary Hypertension
Intervention:   Drug: Ventavis (Iloprost, BAYQ6256)
Sponsor:   Bayer
Active, not recruiting - verified July 2016

An Open-label Extended Clinical Protocol of Ranibizumab to Evaluate Safety and Efficacy in Rare VEGF Driven Ocular Diseases.

Conditions:   Choroidal Neovascularization;   Macular Edema;   Glaucoma, Neovascular;   Diabetic Retinopathy
Intervention:   Drug: ranibizumab
Sponsor:   Novartis Pharmaceuticals
Completed - verified July 2016

Determine the Frequency of a HTPPE in 5 Years (± on 1 Year) After a First Episode of Idiopathic Pulmonary Embolism.

Conditions:   HTPPE;   Idiopathic Pulmonary Embolism
Intervention:   Other: HTPPE
Sponsor:   University Hospital, Brest
Recruiting - verified July 2016

Renal Denervation for Resistant Hypertension

Condition:   Hypertension
Intervention:   Device: Renal Denervation
Sponsor:   Baker IDI Heart and Diabetes Institute
Terminated - verified July 2016

Renal Denervation for Complicated Hypertension

Condition:   Hypertension
Intervention:   Device: Renal Denervation
Sponsor:   Baker IDI Heart and Diabetes Institute
Terminated - verified July 2016

A Study of Tadalafil in Pediatric Participants With Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Interventions:   Drug: Tadalafil;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting - verified July 2016

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Condition:   Kidney Transplantation
Interventions:   Drug: Belatacept;   Drug: Tacrolimus;   Drug: Cyclosporine
Sponsor:   Bristol-Myers Squibb
Recruiting - verified June 2016

Effectiveness of SMS in Diabetes Control

Condition:   Diabetes
Intervention:   Behavioral: SMS MESSAGING
Sponsor:   Basque Health Service
Completed - verified July 2016

Treatment of Pulmonary Hypertension Associated COPD With Inhaled Treprostinil-1

Conditions:   Pulmonary Hypertension;   COPD
Intervention:   Drug: Inhaled Treprostinil Therapy
Sponsor:   University of Colorado, Denver
Completed - verified July 2016

Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Macitentan 10 mg;   Drug: Placebo
Sponsor:   Actelion
Recruiting - verified July 2016

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

Conditions:   Pulmonary Disease;   Pulmonary Hypertension
Intervention:  
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified June 2016

Spironolactone for Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Spironolactone;   Drug: Placebo
Sponsors:   National Institutes of Health Clinical Center (CC);   National Heart, Lung, and Blood Institute (NHLBI);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of Pennsylvania;   University of Maryland;   Washington Hospital Center;   New England Medical Center, Tufts University School of Medicine
Recruiting - verified July 2016

A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn

Condition:   Pulmonary Hypertension, Familial Persistent, of the Newborn
Interventions:   Drug: placebo;   Drug: iv sildenafil
Sponsor:   Pfizer
Recruiting - verified July 2016

Pharmacokinetics of Sildenafil in Premature Infants

Condition:   Persistent Pulmonary Hypertension of the Newborn
Intervention:   Drug: 1 dose of sildenafil
Sponsors:   University of North Carolina, Chapel Hill;   Duke University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   The EMMES Corporation
Recruiting - verified July 2016

Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension

Conditions:   Pulmonary Arterial Hypertension;   Hypertension, Pulmonary
Intervention:   Drug: Sildenafil
Sponsor:   Pfizer
Recruiting - verified July 2016

Sildenafil Versus Placebo in Chronic Heart Failure

Conditions:   Heart Failure;   Pulmonary Hypertension
Interventions:   Drug: Sildenafil;   Drug: Placebo
Sponsors:   Helse Stavanger HF;   Pfizer
Suspended - verified July 2016

Preeclampsia: A Marker for Future Cardiovascular Risk in Women

Conditions:   Preeclampsia;   Pregnancy Induced Hypertension
Intervention:   Drug: Irbesartan
Sponsor:   Brigham and Women's Hospital
Recruiting - verified July 2016

Pravastatin for Prevention of Preeclampsia

Condition:   Preeclampsia
Interventions:   Drug: Pravastatin;   Drug: Placebo
Sponsors:   The University of Texas Medical Branch, Galveston;   University of Texas;   University of Pittsburgh;   Northwestern University
Recruiting - verified June 2016

A Pharmacokinetics Study for Pediatric Participants With Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Tadalafil- Tablet
Sponsor:   Eli Lilly and Company
Recruiting - verified July 2016

Inhaled Iloprost in the Treatment of Patients With Pulmonary Hypertension up to 4 Years

Condition:   Pulmonary Hypertension
Intervention:   Drug: Ventavis inhaled (Iloprost, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified July 2016

Longitudinal Study of Dental Implant Therapy in HIV- Positive Patients

Condition:   Osseointegration Failure of Dental Implant From Complication of Systemic Disease
Intervention:  
Sponsors:   University of Alabama at Birmingham;   Dentsply Implants
Active, not recruiting - verified June 2016

Sunitinib Malate in Treating Patients With Previously Untreated Metastatic Kidney Cancer

Conditions:   Clear Cell Renal Cell Carcinoma;   Stage IV Renal Cell Cancer
Interventions:   Drug: sunitinib malate;   Other: laboratory biomarker analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Genetic: polymorphism analysis
Sponsor:   Case Comprehensive Cancer Center
Active, not recruiting - verified July 2016

Post-authorization Safety Study of Etoricoxib and Other Anti-inflammatory Therapies in European Patients With Ankylosing Spondylitis (MK-0663-163)

Condition:   Ankylosing Spondylitis
Intervention:  
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified July 2016

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction

Conditions:   Hypertension, Pulmonary;   Ventricular Dysfunction, Left
Interventions:   Drug: Riociguat (Adempas, BAY63-2521);   Drug: Riociguat (Adempas, BAY63-2521);   Drug: Riociguat (Adempas, BAY63-2521);   Drug: Placebo
Sponsor:   Bayer
Active, not recruiting - verified July 2016

The Effect of Grape Seed Extract on Blood Pressure in People With Pre-Hypertension

Condition:   Hypertension
Interventions:   Dietary Supplement: grape seed extract;   Dietary Supplement: grape seed extract placebo
Sponsors:   Institute for Food Safety and Health, United States;   Polyphenolics, Inc.
Active, not recruiting - verified July 2016

Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood Asthma (VDAART)

Condition:   Asthma
Interventions:   Dietary Supplement: Vitamin D 3 cholecalciferol;   Dietary Supplement: Vitamin D3
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified July 2016

BAY63-2521:Long-term Extension Study in Patients With Pulmonary Arterial Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified July 2016

Defining Strategies for Improving Endothelial and Fibrinolytic Dysfunction in Obesity

Condition:   Metabolic Syndrome X
Interventions:   Drug: Eplerenone;   Drug: Ramipril
Sponsor:   Vanderbilt University
Terminated - verified July 2016

Modifying Dietary Behavior in Adolescents With Elevated Blood Pressure

Conditions:   Hypertension;   Pre-Hypertension
Interventions:   Behavioral: DASH-4-Teens;   Other: Routine Care
Sponsor:   University of Cincinnati
Completed - verified July 2016

Effectiveness of an Anger and Stress Management Program on Reducing Blood Pressure Levels in Youth

Conditions:   Cardiovascular Diseases;   Hypertension
Interventions:   Behavioral: Williams LifeSkills Stress and Anger Management Workshop;   Behavioral: High school classes
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   Williams LifeSkills
Completed - verified March 2013

Phenylephrine in Spinal Anesthesia in Preeclamptic Patients

Conditions:   Preeclampsia;   Hypotension
Interventions:   Drug: Ephedrine;   Drug: Phenylephrine
Sponsor:   Northwestern University
Recruiting - verified July 2016

Cardiology Biobank Registry

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   Emory University
Recruiting - verified July 2016

Dialysate Sodium Individualization in Hemodialysis

Conditions:   Hypertension;   Hemodialysis Patients
Interventions:   Drug: dialysate sodium individualization;   Drug: standard dialysate sodium
Sponsors:   Yale University;   Satellite Research
Terminated - verified July 2016

20 Year Changes in Fitness & Cardiovascular Disease Risk - Ancillary to CARDIA

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Diabetes Mellitus;   Metabolic Syndrome X;   Hypertension;   Obesity
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified November 2008

Hypertension Education and Treatment Partnership for Reducing Ethnic Differences in the Risk of Cardiovascular Disease

Conditions:   Cardiovascular Diseases;   Hypertension;   Heart Diseases
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2006

Relatively Healthy Male Veterans Observed Over Time to See What Types of Diseases Develop

Condition:   Healthy
Intervention:  
Sponsor:   VA Office of Research and Development
Active, not recruiting - verified July 2016

Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia

Conditions:   Pulmonary Hypertension;   Sickle Cell Anemia;   Sickle Cell Disease
Intervention:  
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified July 2016

Genetics of Hypertension in Blacks

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Hypertension
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified December 2008

Hypertension Detection and Follow-up Program (HDFP)

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Hypertension;   Vascular Diseases
Interventions:   Drug: diuretics;   Drug: antihypertensive agents
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified December 2005

Prevention and Treatment of Hypertension Study (PATHS)

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Hypertension;   Vascular Diseases
Intervention:   Behavioral: behavior therapy
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Completed - verified June 2001