High Blood Pressure

Clinical Trial Finder

Many patients with high blood pressure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Phase III Study of TRC150094 in Improving CV Risk in Subjects With Diabetes, Dyslipidemia and Hypertension

Conditions:   Diabetes;   Dyslipidemias;   Hypertension
Interventions:   Drug: TRC150094;   Drug: Placebo
Sponsors:   Torrent Pharmaceuticals Limited;   QuintilesIMS
Not yet recruiting - verified August 2017

PARP-1 Inhibition in Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Olaparib
Sponsor:   Laval University
Not yet recruiting - verified August 2017

DUCS-DHD Determinants of Hypertension in Tanzania

Conditions:   Hypertension;   Obesity
Intervention:  
Sponsors:   Harvard School of Public Health;   Muhimbili University of Health and Allied Sciences
Completed - verified August 2017

Metformin Versus Vildagliptin for Diabetic Hypertensive Patients

Condition:   Reducing the Elevated Blood Pressure for Diabetic Hypertensive Patients
Interventions:   Drug: Metformin Pill;   Drug: Vildagliptin 50 mg
Sponsor:   MTI University
Completed - verified August 2017

Gene Polymorphisms of Corticosteroid-induced Ocular Hypertension

Condition:   Corticosteroid Induced Ocular Hypertension/Glaucoma
Intervention:   Other: SNP analysis
Sponsor:   Maastricht University Medical Center
Not yet recruiting - verified August 2017

Potassium Supplementation in CKD

Conditions:   Renal Insufficiency, Chronic;   Potassium Depletion;   Hypertension;   Hyperkalemia
Interventions:   Dietary Supplement: Potassium Chloride;   Dietary Supplement: Potassium Citrate;   Dietary Supplement: Placebo
Sponsors:   Erasmus Medical Center;   Dutch Kidney Foundation;   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA);   University Medical Center Groningen;   Leiden University Medical Center
Active, not recruiting - verified August 2017

Sixteen Weeks of Resistance Training in Hypertensive Elderly, Effects on Heart Rate Variability

Condition:   Hypertension
Intervention:   Behavioral: Resistance training
Sponsors:   Federal University of São Paulo;   Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Not yet recruiting - verified August 2017

Characteristics of Obstructive Sleep Apnea Syndrome Related Hypertension and the Effect of Continuous Positive Airway Pressure Treatment on Blood Pressure

Condition:   Hypertension Secondary
Intervention:   Other: continuous positive airway pressure
Sponsors:   Huai'an No.1 People's Hospital;   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified August 2017

The Effects of Stair Climbing on Arterial Stiffness, Blood Pressure and Leg Strength in Stage-1 Postmenopausal Women

Conditions:   Hypertension;   Menopause
Intervention:   Behavioral: Stair climbing
Sponsor:   Pusan National University
Completed - verified August 2017

The Pharmacokinetic Effect of Feeding by Single Dosing of SPH3127 Tablets in Chinese Health Subjects

Condition:   Hypertension
Interventions:   Drug: SPH3127 200mg Panel A;   Drug: SPH3127 200mg Panel B
Sponsor:   Shanghai Pharmaceuticals Holding Co., Ltd
Not yet recruiting - verified August 2017

Role of RDW as Anon Invasive Index for Predicting Liver Cell Failure and Portal Hypertension in Cirrhotic Patient

Condition:   Predicting Liver Cell Failure & Portal Hypertension in LC
Intervention:  
Sponsor:   Assiut University
Recruiting - verified August 2017

Systemic Microvascular Function in Patients With Resistant Hypertension After Renal Sympathetic Denervation

Conditions:   Arterial Hypertension;   Resistant Arterial Hypertension
Intervention:   Procedure: Renal sympathetic denervation
Sponsor:   National Institute of Cardiology, Laranjeiras, Brazil
Recruiting - verified August 2017

Impact of Self-monitoring of Blood Pressure and Self-titration of Medication in the Control of Hypertension (ADAMPA)

Conditions:   Hypertension;   Adjustment;   Adherence, Medication
Intervention:   Other: Self-monitoring/Self-titration
Sponsors:   Fundación para la Investigación del Hospital Clínico de Valencia;   Spanish Clinical Research Network (SCReN);   Carlos III Health Institute
Recruiting - verified August 2017

A Clinical Trial to Evaluate Pharmacokinetic Interactions and Safety Between Fimasartan and Linagliptin in Healthy Male Volunteers

Condition:   Hypertension
Interventions:   Drug: (fimasartan or linagliptin) x 7days;   Drug: (fimasartan and linagliptin) x 7days
Sponsor:   Boryung Pharmaceutical Co., Ltd
Active, not recruiting - verified August 2017

Three Protocols of Phenylephrine Infusion in Cesarean Delivery

Conditions:   Cesarean Section Complications;   Spinal Anesthesia
Interventions:   Drug: single shot phenylephrine;   Drug: fixed infusion phenylephrine;   Drug: variable infusion phenylephrine;   Drug: Bupivacaine
Sponsor:   Cairo University
Not yet recruiting - verified August 2017

Food Resource Equity and Sustainability for Health

Conditions:   BMI;   Blood Pressure
Intervention:   Behavioral: healthy eating and gardening
Sponsor:   University of Oklahoma
Not yet recruiting - verified August 2017

Impedance Cardiography to Decrease the Risk of Preeclampsia

Conditions:   Chronic Hypertension Complicating Pregnancy (Diagnosis);   Preeclampsia
Interventions:   Drug: Labetalol Hydrocholoride 200 mg orally every 12 hours;   Drug: Nifedipine 60 mg orally daily;   Drug: Atenolol 25 mg daily
Sponsor:   High Risk Obstetrical Consultants
Recruiting - verified August 2017

International BPA Registry

Conditions:   Chronic Thromboembolic Pulmonary Hypertension;   CTEPH
Intervention:   Procedure: Balloon pulmonary angioplasty
Sponsor:   International CTEPH Association
Not yet recruiting - verified August 2017

Endoscopic Access Loop With Bilio-enteric Anastomosis: A Prospective Randomized Comparison Between Gastric and Subcutaneous Accesses

Condition:   Jaundice, Obstructive
Interventions:   Procedure: hepaticojejunostomy;   Procedure: modified hepaticojejunostomy with subcutaneous access loop;   Procedure: modified hepaticojejunostomy with gastric access loop
Sponsor:   Assiut University
Not yet recruiting - verified August 2017

Renal Nerve Denervation After Pulmonary Vein Isolation for Persistent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Renal Nerve Denervation;   Procedure: Pulmonary vein isolation
Sponsor:   Chinese University of Hong Kong
Not yet recruiting - verified August 2017

Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy

Condition:   Fuchs' Endothelial Dystrophy
Intervention:   Drug: Ripasudil hydrochloride hydrate 0.4% ophthalmic solution
Sponsor:   Marian Macsai
Not yet recruiting - verified August 2017

Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery

Conditions:   Pre-Eclampsia;   Cesarean Section
Interventions:   Procedure: Spinal Anesthesia;   Drug: Intrathecal Bupivacaine;   Drug: Intrathecal Fentanyl;   Procedure: Cesarean Delivery;   Radiation: Ultrasound Assessment of the Inferior Vena Cava;   Drug: 250 mL Colloid over 5 minutes;   Drug: 250 mL Crystalloid over 5 minutes;   Drug: 500 mL Crystalloid over 55 minutes;   Drug: 250 mL Colloid over 60 minutes;   Drug: 250 mL Crystalloid over 60 minutes;   Drug: Intravenous Ephedrine;   Drug: Intravenous Syntocinon
Sponsor:   Mansoura University
Not yet recruiting - verified August 2017

Fimasartan in the Senior Subjects

Condition:   The Elderly (≥ 70 Years) With Essential Hypertension
Interventions:   Drug: Fimasartan or Fimasartan/Hydrochlorothiazide;   Drug: Perindopril or Perindopril/Indapamide
Sponsor:   Boryung Pharmaceutical Co., Ltd
Recruiting - verified July 2017

The Sleep in Pregnancy Study

Conditions:   Pregnancy Related;   Sleep Disordered Breathing;   Obesity
Intervention:  
Sponsors:   University of Colorado, Denver;   Center for Womens Health Research at University of Colorado Anschutz Medical Campus;   College of Nursing at University of Colorado Anschutz Medical Campus;   Colorado Clinical & Translational Sciences Institute
Recruiting - verified August 2017

The Effects of Citric and Malic Acid Found in Pomegranate Juice on Glycaemic Response to White Bread.

Condition:   Hyperglycemia, Postprandial
Interventions:   Other: Control;   Other: Test
Sponsor:   University of Leeds
Active, not recruiting - verified August 2017

The PK Characteristics of the Co-administration of Rosuvastatin and Telmisartan/Amlodipine and JLP-1401 in Healthy Male Volunteers Volunteers

Condition:   Hypertension With Dyslipidemia
Interventions:   Drug: JLP-1401;   Drug: Telmisartan/Amlodipine, Rosuvastatin
Sponsor:   Jeil Pharmaceutical Co., Ltd.
Recruiting - verified July 2017

HEMOCC Study. Hemostasis in Cirrhotic Children.

Conditions:   Esophageal and Gastric Varices;   Child, Only
Interventions:   Other: Collecting Clinical Data;   Other: Collecting laboratory data
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Completed - verified July 2017

Norepinephrine Versus Phenylephrine Variable Infusion in Cesarean Delivery

Conditions:   Cesarean Section Complications;   Spinal Anesthesia
Interventions:   Drug: Phenylephrine;   Drug: Norepinephrine;   Drug: Bupivacaine
Sponsor:   Cairo University
Not yet recruiting - verified August 2017

RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2

Conditions:   Cardiovascular Disease;   Hypertension
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified July 14, 2017

Isometric Training on Blood Pressure and on the Autonomic Modulation of Hypertensive Patients

Condition:   Hypertension
Intervention:   Behavioral: Intervention Group
Sponsor:   Hospital Israelita Albert Einstein
Recruiting - verified July 2017

Effect of the Intra-abdominal Pressure on the Risk of Delirium in Mechanically Ventilated Patients.

Conditions:   Delirium;   Intraabdominal Hypertension;   Mechanical Ventilation Complication
Intervention:  
Sponsor:   Assiut University
Completed - verified July 2017

Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes

Conditions:   Gestational Diabetes;   Pregnancy Complications;   Weight Gain
Intervention:   Behavioral: Habits-GDM mobile app
Sponsors:   National University Hospital, Singapore;   Jana Care
Not yet recruiting - verified July 2017

Promising Bimarker Prediction of Outcome of HELLP Syndrome.

Conditions:   Pre-Eclampsia, Severe;   HELLP Syndrome;   Microangiopathy
Intervention:   Diagnostic Test: shistocytes percentage
Sponsor:   AYMAN ABDELKADER MOHAMED ABDELKADER
Completed - verified August 2017

Effectiveness and Tolerability of Long-Acting Nifedipine Gastrointestinal Therapeutic System in Chronic Kidney Disease With Uncontrolled Hypertension Patients, a Prospective, Multicenter, Observational Study

Condition:   Hypertension
Intervention:   Drug: Nifedipine controlled-release tablets (Adalat, BAYA1040)
Sponsor:   Bayer
Recruiting - verified August 2017

Losartan and Inflammation in Cystic Fibrosis

Condition:   Cystic Fibrosis
Interventions:   Drug: Losartan;   Drug: placebo
Sponsors:   University of Miami;   University of Alabama at Birmingham;   Children's Hospital Medical Center, Cincinnati
Not yet recruiting - verified August 2017

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

Conditions:   Pheochromocytoma;   Paraganglioma
Interventions:   Drug: Lu-177-DOTATATE;   Drug: Ga-68-DOTATATE;   Other: F-18-FDG;   Drug: Amino Acid
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified July 19, 2017

DASH Cloud: Using Digital Health to Improve Adherence to the DASH Diet Among Women

Conditions:   Diet Modification;   Hypertension;   Women's Health;   Cardiovascular Diseases;   Digital Health
Interventions:   Other: DASH Cloud;   Other: Nutritionix Track app
Sponsor:   Duke University
Recruiting - verified July 2017

Screening and Assessing the Risk Factors and Complications of Chronic Kidney Disease

Condition:   Chronic Kidney Disease
Intervention:   Other: blood sample collection
Sponsor:   Chinese PLA General Hospital
Not yet recruiting - verified August 2017

A Dose-escalation Study in Subjects With Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: GSK2586881
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified August 2017

Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance

Conditions:   Sepsis;   Sepsis Syndrome;   Sepsis, Severe
Intervention:   Diagnostic Test: Blood test: Glukos, SuPAR, Laktat and HBP
Sponsors:   Lisa Kurland;   Örebro University, Sweden
Recruiting - verified August 2017

Combination of Fimasartan/Amlodipine/Rosuvastatin in Patients With Essential Hypertension and Dyslipidemia

Conditions:   Essential Hypertension;   Dyslipidemia
Interventions:   Drug: Fimasartan/Amlodipine, Rosuvastatin;   Drug: Fimasartan/Amlodipine;   Drug: Fimasartan, Rosuvastatin
Sponsor:   Boryung Pharmaceutical Co., Ltd
Recruiting - verified August 2017

A Study Using Transorbital Alternating Current Stimulation for People With Glaucoma

Condition:   Glaucoma
Interventions:   Device: rtACS Stimulation;   Device: Sham Intervention
Sponsor:   New York University School of Medicine
Not yet recruiting - verified August 2017

Right Heart Catheterization Using Magnetic Resonance Imaging Fluoroscopy and Passive Guidewires

Conditions:   Pulmonary Artery Hypertension;   Congenital Heart Disease
Intervention:   Procedure: MRI Right Heart guidewire catheterization
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 30, 2017

ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy

Condition:   Pulmonary Arterial Hypertension (PAH)
Interventions:   Biological: Allogeneic Human Cardiosphere-Derived Stem Cells;   Biological: Placebo
Sponsors:   Cedars-Sinai Medical Center;   California Institute for Regenerative Medicine
Recruiting - verified August 2017

Glaucoma Management Optimism for African Americans Living With Glaucoma

Condition:   Glaucoma
Intervention:   Behavioral: Usual Care + Health Promotion Intervention
Sponsor:   University of Alabama at Birmingham
Not yet recruiting - verified August 2017

Individualized Cognitive Training in HIV

Conditions:   HIV-Associated Cognitive Motor Complex;   Aging;   Cognitive Impairment;   Cognitive Decline;   Attention Impaired;   Processing, Visual Spatial;   Cognitive Deficit in Attention;   Cognitive Disorder in Remission
Interventions:   Behavioral: Individualized Cognitive Training;   Other: No-Contact Control
Sponsors:   University of Alabama at Birmingham;   National Institute of Nursing Research (NINR)
Recruiting - verified August 2017

Evaluation of Electrical Velocimetry for Assessment of Extra-vascular Lung Water in Pre-eclamptic Patients

Condition:   Pre-Eclampsia
Intervention:  
Sponsor:   Cairo University
Recruiting - verified August 2017

EPO-4-Rhesus: Role of Darbepoetin Alfa in Reducing Late Anaemia in Neonates With Red Blood Cell Alloimmunization After Intrauterine Transfusions

Conditions:   Erythroblastosis, Fetal;   Erythroblastosis Fetalis, Rh Disease;   Erythroblastosis Fetalis Due to RH Antibodies;   Erythroblastosis Fetalis Due to Isoimmunization
Intervention:   Drug: Darbepoetin Alfa
Sponsors:   Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research;   Leiden University Medical Center
Not yet recruiting - verified August 2017

Preserve-Transplant Study

Conditions:   Acidosis;   Renal Insufficiency;   Kidney Transplantation
Interventions:   Drug: Nephrotrans;   Other: Placebo
Sponsor:   University of Zurich
Recruiting - verified August 2017

A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

Condition:   Heart Failure With Preserved Ejection Fraction
Interventions:   Drug: Macitentan;   Drug: Placebo
Sponsor:   Actelion
Recruiting - verified August 2017

Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT)

Condition:   Hypertension
Interventions:   Drug: Peri;   Drug: HCTZ
Sponsor:   Ospedale San Raffaele
Recruiting - verified August 2017

Premom: Pregnancy Remote Monitoring

Condition:   Pregnancies, Cardiovascular Complications
Intervention:   Other: monitoring
Sponsors:   Hasselt University;   Ziekenhuis Oost-Limburg
Completed - verified August 2017

Evaluation of Renal Function in Patients With Pulmonary Hypertension Undergoing Right Heart Catheterization

Condition:   Pulmonary Hypertension
Intervention:   Diagnostic Test: No intervention
Sponsor:   University of Giessen
Recruiting - verified August 2017

Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Heart Failure With Preserved Ejection Fraction (HFpEF)

Conditions:   Pulmonary Hypertension;   Heart Failure With a Preserved Ejection Fraction
Interventions:   Drug: Oral treprostinil;   Drug: Placebo
Sponsor:   United Therapeutics
Recruiting - verified August 2017

Clinical Characteristics, Anti-hyperglycaemic Treatment Pattern and Target Attainment of Type 2 Diabetes Mellitus Patients in Older Population With or Without Albuminuria in China

Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: No Treatment
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

The Prophet Trial - Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients With Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Intervention:   Device: Occlutech AFR Device
Sponsor:   Occlutech International AB
Recruiting - verified August 2017

Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome

Conditions:   Prostate Cancer;   Metabolic Syndrome
Interventions:   Drug: Metformin;   Drug: Placebo Oral Tablet
Sponsors:   Canadian Urologic Oncology Group;   Prostate Cancer Canada;   British Columbia Cancer Agency
Not yet recruiting - verified August 2017

Investigating Idiopathic Pulmonary Fibrosis in Greece (INDULGE IPF)

Condition:   Idiopathic Pulmonary Fibrosis
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Study of the Efficacy and Safety of DigiFab® in Antepartum Subjects With Severe Preeclampsia

Condition:   Severe Preeclampsia
Interventions:   Biological: Digoxin immune fab;   Other: Placebo
Sponsor:   Velo Bio, LLC
Recruiting - verified August 2017

A Study to Compare the Pharmacokinetics and Safety of a Fixed Dose Combination of Fimasartan/Amlodipine/Rosuvastatin

Condition:   Hypertension, Hyperlipidemia
Intervention:   Drug: Fimasartan/Amlodipine combination drug, Rosuvastatin
Sponsor:   Boryung Pharmaceutical Co., Ltd
Completed - verified August 2017

A Clinical Trial to Evaluate the Pharmacokinetics and Safety/Tolerability of Fimasartan and Atorvastatin in Healthy Male Volunteers.

Condition:   Hypertension, Hyperlipidemia
Intervention:   Drug: Fimasartan, Atorvastatin
Sponsor:   Boryung Pharmaceutical Co., Ltd
Recruiting - verified August 2017

Clinical Evaluation of CATS Tonometer Prism

Condition:   Ocular Hypertension
Interventions:   Device: CATS tonometer prism;   Device: Goldmann tonometer prism
Sponsor:   Intuor Technologies, Inc.
Recruiting - verified August 2017

A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction

Conditions:   Pulmonary; Hypertension;   Heart Failure;   Preserved Ejection Fraction
Interventions:   Drug: Nitrates;   Drug: Nitrates
Sponsors:   University of Pittsburgh;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2017

Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury

Condition:   TBI
Interventions:   Drug: Sildenafil citrate;   Device: Functional Near Infared Spectroscopy;   Other: Hypercapnia Challenge
Sponsor:   University of Pennsylvania
Recruiting - verified August 2017

A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Acute Gouty Arthritis

Condition:   Acute Gouty Arthritis
Interventions:   Drug: Anakinra 100 mg;   Drug: Triamcinolone Acetonide 40 mg;   Drug: Placebo to Anakinra 100 mg;   Drug: Placebo to Triamcinolone Acetonide 40 mg
Sponsor:   Swedish Orphan Biovitrum
Recruiting - verified August 2017

Care Coordination for Complex Cancer Survivors in an Integrated Safety Net System

Conditions:   Breast Cancer;   Colorectal Cancer
Intervention:   Other: Care Coordination Strategies
Sponsor:   University of Texas Southwestern Medical Center
Not yet recruiting - verified August 2017

Sleep Extension and Blood Pressure

Condition:   Sleep Extension
Interventions:   Behavioral: sleep extension;   Behavioral: sleep maintenance
Sponsor:   Mayo Clinic
Recruiting - verified August 2017

A Multicenter Study to Evaluate the ROX Coupler in Subjects With Hypertension

Conditions:   Hypertension;   High Blood Pressure
Interventions:   Device: ROX Coupler;   Other: Sham procedure
Sponsor:   ROX Medical, Inc.
Recruiting - verified August 2017

Study of CS-3150 in Patients With Essential Hypertension

Condition:   Essential Hypertension
Interventions:   Drug: CS-3150;   Drug: Eplerenone
Sponsor:   Daiichi Sankyo Co., Ltd.
Completed - verified August 2017

Mechanisms of Cerebrovascular Control

Condition:   Metabolic Syndrome X
Interventions:   Drug: NOS Inhibition;   Drug: ET-1 Inhibition;   Drug: Placebo;   Device: 3 Tesla MRI;   Device: Intravenous Catheter;   Other: Oral Glucose Tolerance Test
Sponsor:   University of Wisconsin, Madison
Recruiting - verified August 2017

Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Adempas (Riociguat, BAY63-2521);   Drug: Sildenafil;   Drug: Tadalafil
Sponsor:   Bayer
Recruiting - verified August 2017

Study of CS-3150 in Patients With Primary Aldosteronism

Condition:   Primary Aldosteronism
Intervention:   Drug: CS-3150
Sponsor:   Daiichi Sankyo Co., Ltd.
Completed - verified August 2017

Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation

Conditions:   Graft vs Host Disease;   Congenital Aniridia;   Chemical Burns;   Stevens-Johnson Syndrome;   Congenital Glaucoma
Intervention:   Device: ARGOS-IO system
Sponsor:   Implandata Ophthalmic Products GmbH
Completed - verified August 2017

OPTImizing Precision of Hypertension Care to Maximize Blood Pressure Control Pilot (OPTI-BP Pilot)

Condition:   High Blood Pressure
Interventions:   Other: HTN PRA App;   Other: Blood Sample
Sponsors:   University of Florida;   OneFlorida Clinical Research Consortium
Active, not recruiting - verified August 2017

Non-interventional, Postauthorization Safety Study of Ventavis for Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Ventavis (Iloprost, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified August 2017

Study of CS-3150 in Combination With ARB or ACE Inhibitor in Hypertensive Patients With Moderate Renal Impairment

Condition:   Hypertension With Moderate Renal Impairment
Intervention:   Drug: CS-3150
Sponsor:   Daiichi Sankyo Co., Ltd.
Completed - verified August 2017

Hypertension and Injury

Conditions:   Arterial Hypertension;   CAD
Intervention:  
Sponsor:   Klinik für Kardiologie, Pneumologie und Angiologie
Active, not recruiting - verified August 2017

Open-label, Single Arm Trial of BI 695502 in Patients With Previously Untreated Metastatic Colorectal Cancer

Condition:   Colorectal Neoplasms
Interventions:   Drug: BI 695502;   Drug: chemotherapy
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension.

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Adempas (Riociguat, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified August 2017

Effects of Empagliflozin + Linagliptin vs Metformin + Insulin Glargine on Renal and Vascular Changes in Type 2 Diabetes

Condition:   Diabetes Mellitus Type 2
Interventions:   Drug: Empagliflozin and Linagliptin;   Drug: Metformin and Insulin sc
Sponsors:   Institut für Pharmakologie und Präventive Medizin;   University of Erlangen-Nürnberg Medical School
Recruiting - verified August 2017

Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension

Condition:   Essential Hypertension
Intervention:   Drug: CS-3150
Sponsor:   Daiichi Sankyo Co., Ltd.
Completed - verified August 2017

Hepatic Arterial Infusion Chemotherapy(HAIC) for Hepatoma After Resection

Condition:   Hepatocellular Carcinoma
Interventions:   Drug: Oxaliplatin(OXA), 5-fluorouracil (5-FU);   Procedure: Hepatic arterial catheter implantation
Sponsor:   Beijing Cancer Hospital
Recruiting - verified August 2017

SToRytelling to Improve DiseasE Outcomes in GOut: The STRIDE-GO 2 Study

Conditions:   Gout;   Low Medication Adherence;   Health Related Quality of Life
Intervention:   Behavioral: Improvement of Medication Adherence
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2017

A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects

Condition:   Hypertension, Pulmonary
Interventions:   Drug: FDC (ambrisentan 10 mg-tadalafil 40 mg) single dose;   Drug: Reference (ambrisentan 10 mg + tadalafil 40 mg given concurrently)
Sponsors:   GlaxoSmithKline;   Covance Harrogate;   Hammersmith Medicines Research
Completed - verified August 2017

Renal Sympathetic Denervation in Moderate to Severe Chronic Kidney Disease

Conditions:   Hypertension;   Chronic Kidney Disease
Intervention:   Device: Renal Sympathetic Denervation
Sponsor:   Heart of England NHS Trust
Completed - verified August 2017

A Study to Assess Long-Term Safety of the CyPass Micro-Stent in Patients Completing the COMPASS Trial

Condition:   Primary Open Angle Glaucoma (POAG)
Interventions:   Device: CyPass Micro-Stent;   Procedure: Cataract Surgery
Sponsors:   Alcon Research;   Transcend Medical, Inc.
Active, not recruiting - verified August 2017

Induction Versus Expectant Management With Abnormal Maternal Biochemical Markers

Condition:   PREGNANCY
Interventions:   Other: Induction of labour;   Other: Expectant management
Sponsor:   HaEmek Medical Center, Israel
Recruiting - verified August 2017

Clinical Study of Pulsed, Inhaled Nitric Oxide Versus Placebo in Symptomatic Subjects With PAH

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Inhaled Nitric Oxide 75 mcg/kg IBW/hr;   Drug: Placebo
Sponsors:   Bellerophon Pulse Technologies;   Worldwide Clinical Trials
Recruiting - verified August 2017

A Study of the ReCor Medical Paradise System in Clinical Hypertension

Conditions:   Hypertension;   Vascular Diseases
Interventions:   Device: The Paradise® Renal Denervation Ultrasound System;   Device: Sham Procedure
Sponsor:   ReCor Medical, Inc.
Recruiting - verified May 2017

Integrating Online Weight Management With Primary Care Support

Condition:   Obesity
Interventions:   Behavioral: Online weight management program;   Behavioral: Population health management support
Sponsors:   Brigham and Women's Hospital;   Patient-Centered Outcomes Research Institute
Active, not recruiting - verified August 2017

A Study Investigating Routine Practice of Chronic Thromboembolic Pulmonary Hypertension Management in EMEA Countries

Condition:   Hypertension, Pulmonary
Intervention:   Other: Standard of care
Sponsor:   Bayer
Recruiting - verified August 2017

Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis

Conditions:   Renal Failure;   End Stage Renal Disease;   Hemodialysis;   Vascular Access
Interventions:   Biological: Human Acellular Vessel (HAV);   Device: ePTFE graft
Sponsors:   Humacyte, Inc.;   CTI Clinical Trial and Consulting Services
Recruiting - verified August 2017

Riociguat in Children With Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsors:   Bayer;   Merck Sharp & Dohme Corp.
Recruiting - verified August 2017

Atorvastatin Effectiveness and Safety in Cardiology Patients in Real World Setting

Condition:   Coronary Artery Disease, Hypercholesterolemia, Hypertension
Intervention:   Other: No intervention
Sponsor:   Pfizer
Recruiting - verified August 2017

Egypt Hypertension Study

Condition:   Different Classes of the Antihypertensive Treatment
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2017

Systemic Sclerosis (SSc) Vasculopathy: Improved Clinical Monitoring and Treatment

Condition:   Rheumatologic Disease
Interventions:   Drug: BH4;   Other: Vasculopathy assessment;   Drug: Placebo
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2017

Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease

Conditions:   Chronic Kidney Disease;   Albuminuria
Interventions:   Drug: Spironolactone;   Drug: Amiloride
Sponsors:   University of Alabama at Birmingham;   National Institutes of Health (NIH)
Recruiting - verified August 2017

The Effects of CPAP Withdrawal on Cerebral Vascular Reactivity and Brain Oxygenation in OSA

Condition:   Sleep Apnea, Obstructive
Intervention:   Device: Continuous positive airway pressure device
Sponsor:   University of Zurich
Recruiting - verified August 2017

SPYRAL HTN-ON MED Study

Conditions:   Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions:   Device: Symplicity Spyral™ multi-electrode renal denervation system;   Procedure: Sham Procedure
Sponsor:   Medtronic Vascular
Recruiting - verified August 2017

SPYRAL HTN-OFF MED Study

Conditions:   Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions:   Device: Symplicity Spyral™ multi-electrode renal denervation system;   Procedure: Sham Procedure
Sponsor:   Medtronic Vascular
Recruiting - verified August 2017

Study Comparing Lutonix AV Drug Coated Balloon vs Standard Balloon for Treatment of Dysfunctional AV Fistulae

Condition:   Arteriovenous Fistula
Interventions:   Combination Product: Lutonix DCB;   Device: Standard Balloon Angioplasty Catheter;   Procedure: Percutaneous Transluminal Angiography
Sponsor:   C. R. Bard
Active, not recruiting - verified August 2017

Safety for 24 Weeks Intake of Korean Red Ginseng in Adults

Conditions:   Healthy;   Diabetes;   Hypertension;   Hyperlipidemia
Interventions:   Dietary Supplement: Korean Red Ginseng;   Dietary Supplement: Placebo
Sponsor:   Korea Ginseng Corporation
Completed - verified August 2017

A Study of Vonapanitase (PRT-201) Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-2)

Condition:   Chronic Kidney Disease
Interventions:   Drug: vonapanitase;   Drug: Placebo
Sponsor:   Proteon Therapeutics
Recruiting - verified August 2017

Lowering Blood Pressure in Primary Care in Vienna

Condition:   Hypertension
Intervention:   Drug: Olmesartan medoxomil, amlodipine, hydrochlorothiazide
Sponsors:   Wilhelminenspital Vienna;   Association for the Promotion of Research in Atherosclerosis, Thrombosis and Vascular Biology;   Ludwig Boltzmann Foundation for Cardiovascular Research
Completed - verified August 2017

Stress Echocardiography Versus Exercise ECG (ExECG) in Women With Chest Pain

Condition:   Coronary Artery Disease
Interventions:   Procedure: Exercise ECG;   Procedure: Stress Echocardiography
Sponsor:   London North West Healthcare NHS Trust
Recruiting - verified March 2017

Minority Health Genomics and Translational Research Bio-Repository Database (MH-GRID)-2.0

Condition:   Hypertension
Intervention:  
Sponsors:   National Human Genome Research Institute (NHGRI);   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified August 3, 2017

A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability

Condition:   Hypotension
Interventions:   Device: vasopressor delivery automated system;   Drug: phenylephrine;   Drug: ephedrine;   Device: manual vasopressor delivery
Sponsor:   KK Women's and Children's Hospital
Active, not recruiting - verified August 2017

Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years

Condition:   PAH
Intervention:   Drug: oral treprostinil
Sponsor:   United Therapeutics
Completed - verified August 2017

Non-invasive Assessment of Pulmonary Artery Pressure

Condition:   Pulmonary Hypertension
Intervention:  
Sponsors:   Medical University of Graz;   National Bank of Austria;   Ludwig Boltzmann Institute for Lung Vascular Research
Completed - verified August 2017

Study 3: Minocycline Decreases Microglia Activation

Condition:   Hypertension
Intervention:   Drug: Minocycline
Sponsors:   University of Florida;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2017

MOMENTUM 3 IDE Clinical Study Protocol

Condition:   Advanced Refractory Left Ventricular Heart Failure
Interventions:   Device: HeartMate 3 LVAS;   Device: HeartMate II LVAS
Sponsors:   Thoratec Corporation;   St. Jude Medical
Active, not recruiting - verified August 2017

24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension

Conditions:   Diabetes Mellitus, Type 2;   Hypertension
Interventions:   Drug: Empagliflizon low dose;   Drug: placebo;   Drug: Empagliflizon high dose
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Completed - verified August 2017

Assessing Portal Hypertension With Methacetin Breath Test

Condition:   Patients With Compensated Liver Cirrhosis
Intervention:   Device: Methacetin Breath Test
Sponsor:   Exalenz Bioscience LTD.
Recruiting - verified August 2017

Study 1: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients

Condition:   Hypertension
Interventions:   Drug: Minocycline 100mg Group;   Drug: Minocycline 200mg Group
Sponsors:   University of Florida;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2017

Perioperative Blood Pressures and Chronic Hypertension

Condition:   Hypertension
Intervention:  
Sponsors:   Yale University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified March 2017

OPsumit USers Registry

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Opsumit (macitentan)
Sponsor:   Actelion
Recruiting - verified August 2017

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Condition:   Carotid Stenosis
Interventions:   Procedure: Carotid endarterectomy (CEA);   Device: Carotid Stenting (CAS);   Other: Intensive Medical Management - no CEA;   Other: Intensive Medical Management - no CAS
Sponsors:   Thomas G. Brott, M.D.;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2017

Optimizing Pazopanib Exposure in RCC Patients

Conditions:   Locally Advanced Renal Cell Carcinoma;   Metastatic Renal Cell Carcinoma
Intervention:   Drug: Pazopanib
Sponsors:   Interessenverband zur Qualitätssicherung der Arbeit niedergelassener Uro-Onkologen in Deutschland e.;   OnkoDataMed GmbH
Terminated - verified August 2017

Timing of Glaucoma Drainage Device With Boston KPro Surgery

Conditions:   Corneal Diseases;   Corneal Opacity
Interventions:   Device: Boston keratoprosthesis type 2;   Device: Glaucoma drainage device
Sponsors:   Centre hospitalier de l'Université de Montréal (CHUM);   Centre de Recherche du Centre Hospitalier de l'Université de Montréal
Recruiting - verified August 2017

Effects of Oral Sildenafil on Mortality in Adults With PAH

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: sildenafil citrate;   Drug: sildenafil citrate;   Drug: sildenafil citrate
Sponsor:   Pfizer
Recruiting - verified August 2017

Randomized Trial Comparing Diltiazem and Metoprolol For Atrial Fibrillation Rate Control

Conditions:   Atrial Fibrillation;   Atrial Flutter
Interventions:   Drug: Metoprolol;   Drug: Diltiazem
Sponsor:   CAMC Health System
Recruiting - verified August 2017

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

Conditions:   Ischemic Stroke;   Atrial Fibrillation;   Transient Ischemic Attacks;   Transient Cerebrovascular Events;   Thrombotic Stroke;   Stroke of Basilar Artery;   Cardioembolic Stroke
Intervention:   Other: Biomarker blood draw
Sponsor:   Ischemia Care LLC
Recruiting - verified August 2017

A Randomized Trial of Induction Versus Expectant Management

Condition:   Labor and Delivery
Intervention:   Procedure: Elective Induction of Labor
Sponsors:   The George Washington University Biostatistics Center;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified August 2017

Evaluation of Sickle Cell Liver Disease

Condition:   Sickle Cell Disease
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified August 4, 2017

A Phase II Study to Evaluate the Additivity of Trabodenoson to Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma

Conditions:   Primary Open-Angle Glaucoma (POAG);   Ocular Hypertension (OHT)
Interventions:   Drug: Trabodenoson;   Drug: Latanoprost;   Drug: Timolol
Sponsor:   Inotek Pharmaceuticals Corporation
Completed - verified August 2017

Controlling and Lowering Blood Pressure With The MOBIUSHD™ (CALM-FIM_EUR)

Condition:   Hypertension
Intervention:   Device: MobiusHD
Sponsor:   Vascular Dynamics, Inc.
Active, not recruiting - verified August 2017

Sildenafil Therapy For Subjects Who Derive Clinical Benefit From Continued Treatment With Sildenafil

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: sildenafil
Sponsor:   Pfizer
Available - verified August 2017

Cardiovascular, Cerebrovascular, and Cognitive Function in Spinal Cord Injury

Condition:   Spinal Cord Injury
Intervention:  
Sponsor:   James J. Peters Veterans Affairs Medical Center
Active, not recruiting - verified August 2017

Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement

Conditions:   Hydrocephalus;   Idiopathic Intracranial Hypertension;   Pseudotumor Cerebri
Interventions:   Device: Tympanic membrane displacement (TMD);   Device: DPOAE
Sponsor:   LifeBridge Health
Terminated - verified August 2017

MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy

Conditions:   Chronic Liver Disease;   Cirrhosis;   Esophageal Varices;   Portal Hypertension;   Bleeding
Intervention:   Device: Methacetin (with Breath testing device)
Sponsor:   Exalenz Bioscience LTD.
Completed - verified January 2017

Optimizing Linkage and Retention to Hypertension Care in Rural Kenya

Conditions:   Hypertension;   High Blood Pressure
Interventions:   Behavioral: behavioral communication strategy;   Behavioral: Behavioral communication strategy, plus smartphone-based tool
Sponsors:   Icahn School of Medicine at Mount Sinai;   Moi University
Recruiting - verified August 2017

A Pilot Study of Pre- and Post-operative Use of Somatuline Depot.

Condition:   Acromegaly
Intervention:   Drug: lanreotide
Sponsor:   John Wayne Cancer Institute
Terminated - verified August 2017

Study Of Diabetic Nephropathy With Atrasentan

Condition:   Diabetic Nephropathy
Interventions:   Drug: Atrasentan;   Drug: Placebo
Sponsor:   AbbVie
Recruiting - verified August 2017

Bosentan In Exercise Induced Pulmonary Arterial Hypertension in CongenitaL Heart diseasE

Conditions:   Pulmonary Arterial Hypertension;   Congenital Heart Disease
Interventions:   Drug: Bosentan;   Drug: Placebo
Sponsor:   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Active, not recruiting - verified August 2017

The Six Minute Walk Test: Influence of Instruction on Results

Condition:   Interstitial Lung Disease
Interventions:   Procedure: alternative six minute walk test;   Procedure: Standard six minute walk test
Sponsors:   Inova Health Care Services;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 2017

EBMtrialcentral- Comparing Initial Diuretic Therapies Using a Collaborative Network

Condition:   Hypertension
Interventions:   Drug: Chlorthalidone;   Drug: Hydrochlorothiazide
Sponsor:   Johns Hopkins University
Withdrawn - verified August 2017

Non-contrast Enhanced Cardiac Magnetic Resonance Imaging in the Diagnosis and Classification of Pulmonary Hypertension

Conditions:   Pulmonary Hypertension;   Elevated Mean Pulmonary Arterial Pressure;   Normal Mean Pulmonary Arterial Pressure
Intervention:   Other: Cardiac MRI
Sponsor:   Medical University of Graz
Enrolling by invitation - verified October 2016

A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn

Condition:   Pulmonary Hypertension, Familial Persistent, of the Newborn
Interventions:   Drug: placebo;   Drug: iv sildenafil
Sponsor:   Pfizer
Recruiting - verified August 2017

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Sildenafil Versus Placebo in Chronic Heart Failure

Conditions:   Heart Failure;   Pulmonary Hypertension
Interventions:   Drug: Sildenafil;   Drug: Placebo
Sponsors:   Helse Stavanger HF;   Pfizer
Recruiting - verified August 2017

Database for Clinical and Anamnestic Data in Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Intervention:  
Sponsor:   Medical University of Graz
Recruiting - verified August 2017

Post-Authorisation Safety Cohort Observation of RetacritTM (Epoetin Zeta) Administered Subcutaneously for the Treatment of Renal Anaemia

Conditions:   Renal Anemia;   Pregnancy;   Lactation
Intervention:  
Sponsors:   Pfizer;   Hospira, now a wholly owned subsidiary of Pfizer
Recruiting - verified August 2017

Inhaled Iloprost in the Treatment of Patients With Pulmonary Hypertension up to 4 Years

Condition:   Pulmonary Hypertension
Intervention:   Drug: Ventavis inhaled (Iloprost, BAYQ6256)
Sponsor:   Bayer
Active, not recruiting - verified August 2017

Direct Application of Selective Laser Trabeculoplasty in Open Angle Glaucoma

Condition:   Glaucoma
Intervention:   Device: Automated Direct Selective Trabeculoplasty device
Sponsors:   Sheba Medical Center;   Belkin Laser Ltd.
Active, not recruiting - verified August 2017

Hyperpolarized 129Xe MRI for Imaging Pulmonary Function

Conditions:   Asthma;   Chronic Obstructive Pulmonary Disease;   Interstitial Lung Disease;   Cystic Fibrosis;   Pulmonary Hypertension
Intervention:   Drug: Xenon
Sponsor:   Bastiaan Driehuys
Recruiting - verified August 2017

A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt Nephropathy

Condition:   Diabetic Nephropathies
Interventions:   Drug: PF-00489791;   Drug: Placebo
Sponsor:   Pfizer
Completed - verified August 2017

Auto-immunity and Pulmonary Arterial Hypertension

Conditions:   Pulmonary Arterial Hypertension;   HIV Infection;   Congenital Heart Defect;   Systemic Sclerosis;   Connective Tissue Disease
Interventions:   Procedure: skin biopsy;   Other: Blood Sample
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed - verified August 2017

Sunitinib Malate in Treating Patients With Previously Untreated Metastatic Kidney Cancer

Conditions:   Clear Cell Renal Cell Carcinoma;   Stage IV Renal Cell Cancer
Interventions:   Drug: sunitinib malate;   Other: laboratory biomarker analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Genetic: polymorphism analysis
Sponsor:   Case Comprehensive Cancer Center
Completed - verified August 2017

BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified August 2017

Cognitive Impairment in Kidney Disease

Condition:   Kidney Insufficiency, Chronic
Intervention:  
Sponsor:   VA Office of Research and Development
Completed - verified August 2017

Impact of Multiple Doses of BAY63-2521 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Patients With Interstitial Lung Disease (ILD) Associated Pulmonary Hypertension (PH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified August 2017

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Macitentan
Sponsor:   Actelion
Active, not recruiting - verified August 2017

Evaluation of Potential for Orthostatic Hypotension in Elderly Hypertensives

Condition:   Hypertension
Interventions:   Drug: Carvedilol CR capsules;   Drug: Placebo;   Drug: Lisinopril
Sponsor:   GlaxoSmithKline
Completed - verified August 2017