High Blood Pressure

Clinical Trial Finder

Many patients with high blood pressure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Team-Based Care for Hypertension Management (TBC-HTA)

Condition:   Hypertension
Intervention:   Behavioral: TBC intervention
Sponsors:   Centre Hospitalier Universitaire Vaudois;   University of Applied Sciences of Western Switzerland;   Université du Québec à Trois-Rivières;   McGill University
Recruiting - verified July 2015

Tele-Pharmacy Intervention to Improve Treatment Adherence

Conditions:   Hyperlipidemia;   Diabetes;   Hypertension
Intervention:   Behavioral: Telepharmacist intervention
Sponsors:   Brigham and Women's Hospital;   Harvard Vanguard Medical Associates
Not yet recruiting - verified July 2015

Bioequivalence Study With Clinical Endpoint Comparing Brinzolamide 1% Ophthalmic Suspension to Azopt® 1% Ophthalmic Suspension In the Treatment of Chronic Open Angle Glaucoma or Ocular Hypertension in Both Eyes

Condition:   Glaucoma
Interventions:   Drug: Test-Brinzolamide 1% Ophthalmic suspension;   Drug: Reference-Brinzolamide 1% Ophthalmic suspension
Sponsor:   Actavis Inc.
Recruiting - verified July 2015

Beta-blockers in Pulmonary Arterial Hypertension - A Phase 2 Double-Blind, Placebo-Controlled, Crossover Study Evaluating the Efficacy

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: carvedilol;   Drug: Placebo
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - verified July 2015

Hypertension With Unsatisfactory Sleep Health

Conditions:   Insomnia;   Hypertension
Interventions:   Behavioral: Brief Behavioral Treatment for Insomnia;   Behavioral: Sleep Healthy Using the Internet;   Behavioral: Enhanced Usual Care
Sponsors:   University of Pittsburgh;   University of Virginia;   Carolinas Medical Center;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified July 2015

Effect of Administration of Rifaximin on the Portal Pressure of Patients With Liver Cirrhosis and Esophageal Varices

Conditions:   Liver Cirrhosis;   Portal Hypertension
Interventions:   Drug: Rifaximin;   Drug: Placebo
Sponsor:   University of Padua
Recruiting - verified July 2015

Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension

Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension
Interventions:   Drug: Bimatoprost SR;   Other: Sham Bimatoprost SR;   Procedure: Selective Laser Trabeculoplasty;   Other: Sham Selective Laser Trabeculoplasty
Sponsor:   Allergan
Not yet recruiting - verified July 2015

Interventional Radiology for the Treatment of Symptomatic Portal Hypertension in Patients With Cavernous Transformation of Portal Vein

Conditions:   Portal Vein, Cavernous Transformation Of;   Hypertension, Portal
Interventions:   Procedure: Transhepatic portosystemic shunt;   Device: 6-French sheath;   Device: 22-gauge chiba needle;   Device: 260-cm-long stiff shaft wire;   Device: Balloon catheter;   Device: Bare metal stent;   Device: Covered stent
Sponsor:   Sun Yat-sen University
Recruiting - verified July 2015

Transhepatic Portosystemic Shunt for Treatment of Symptomatic Portal Hypertension With Portal Vein Occlusion After Splenectomy

Conditions:   Hypertension, Portal;   Portal Vein, Cavernous Transformation Of
Intervention:   Procedure: Transhepatic portosystemic shunt
Sponsor:   Sun Yat-sen University
Recruiting - verified July 2015

Renal Hemodynamic Effects of the HMG-CoA Reductase Inhibitors in Normal Volunteers and in Patients With Chronic Renal Failure

Conditions:   Hyperlipidemia;   Hypertension;   Chronic Renal Failure
Intervention:   Drug: Simvastatin
Sponsor:   Mayo Clinic
Completed - verified July 2015

Cavernous Transformation of Portal Vein: Etiology, Diagnosis, Management and Prognosis

Condition:   Portal Vein, Cavernous Transformation Of
Intervention:  
Sponsor:   Sun Yat-sen University
Recruiting - verified July 2015

Optic Nerve Sheath Diameter and Intracranial Pressure (ICP) in Children

Condition:   Intracranial Hypertension
Intervention:   Procedure: ultrasound
Sponsor:   Anna Rominger
Not yet recruiting - verified July 2015

Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0

Conditions:   Myelomeningocele;   Pregnancy
Intervention:   Procedure: Open Fetal Repair of Myelomeningocele
Sponsor:   St. Louis University
Recruiting - verified July 2015

Addressing Racial/Ethnic Tobacco Health Disparities Via Group Intervention

Condition:   Smoking Cessation
Interventions:   Behavioral: Group Cognitive Behavioral Therapy;   Behavioral: General Health Education;   Drug: Transdermal Nicotine Patch
Sponsors:   University of Miami;   H. Lee Moffitt Cancer Center and Research Institute
Not yet recruiting - verified July 2015

Safety and Pharmacokinetics of Besylsartan Tablet in Healthy Male Subject

Condition:   Hypertension
Interventions:   Drug: Besylsartan;   Drug: Amosartan
Sponsor:   Huons Co.,Ltd.
Completed - verified July 2015

Burdock and Blood Pressure in African-American Women

Condition:   Hypertension
Interventions:   Dietary Supplement: Burdock;   Dietary Supplement: Placebo
Sponsor:   Proactive Health Labs
Not yet recruiting - verified July 2015

MIGS VS SLT Comparison in Glaucoma Patients

Condition:   Glaucoma
Interventions:   Device: MIGS Hydrus Ivantis;   Procedure: 360 degrees SLT
Sponsors:   University of Turin, Italy;   University of Siena
Active, not recruiting - verified July 2015

Carvedilol as an Adjunct to Endoscopic Cyanoacrylate Injection for Secondary Prophylaxis of Gastric Variceal Bleeding

Condition:   Esophageal and Gastric Varices
Interventions:   Drug: carvedilol;   Drug: cyanoacrylate
Sponsor:   Kaohsiung Veterans General Hospital.
Recruiting - verified July 2015

Potential Mechanism of Exercise Impairment in OSA

Condition:   Obstructive Sleep Apnea
Intervention:  
Sponsor:   University of California, San Diego
Recruiting - verified July 2015

Novel Parameters for the Prediction of Ventriculoperitoneal Shunting Efficacy in Patients With iNPH

Condition:   Idiopathic Normal Pressure Hydrocephalus
Intervention:   Other: Gait analysis and  MRI:
Sponsor:   University of Zurich
Recruiting - verified July 2015

Effects of Iloprost on Pulmonary Hemodynamics and Oxygenation in Patients of Chronic Obstructive Pulmonary Disease During One-lung Ventilation

Conditions:   Video-assisted Thoracoscopic Surgery;   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Inhaled iloprost;   Drug: normal saline (Saline 0.9%)
Sponsor:   Yonsei University
Recruiting - verified July 2015

Effects of Incretin on the Blood Pressure and Lipid in Patients With Overweight or Obese Diabetes

Conditions:   Type 2 Diabetes;   Overweight;   Obesity;   Masked Hypertension
Interventions:   Drug: "Liraglutide" and "Mitiglinide";   Drug: "Metformin" and "Mitiglinide";   Drug: "Mitiglinide"
Sponsor:   Third Affiliated Hospital of Third Military Medical University
Active, not recruiting - verified July 2015

SPYRAL HTN-ON MED Study

Conditions:   Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions:   Device: Symplicity Spyral™ multi-electrode renal denervation system;   Procedure: Sham Procedure
Sponsor:   Medtronic Vascular
Recruiting - verified July 2015

SPYRAL HTN-OFF MED Study

Conditions:   Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions:   Device: Symplicity Spyral™ multi-electrode renal denervation system;   Procedure: Sham Procedure
Sponsor:   Medtronic Vascular
Recruiting - verified July 2015

Efficacy, Safety and Pharmacokinetic Study of Intravenous Clonidine Versus Midazolam for Sedation in Paediatric Patients

Condition:   Sedation in Intensive Care
Interventions:   Drug: Clonidine;   Drug: Midazolam
Sponsors:   University of Erlangen-Nürnberg Medical School;   Erasmus Medical Center;   University of Tartu;   Therakind Ltd;   Gianni Benzi Pharmacological Research Foundation;   University College, London;   Karolinska Institutet;   Univerzita Karlova v Praze;   Vereniging Samenwerkende Ouder- En Patientenorganisaties;   Bambino Gesù Hospital and Research Institute;   European Commission
Not yet recruiting - verified July 2015

SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)

Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: Brinzolamide 1%/brimonidine 0.2% tartrate ophthalmic suspension;   Drug: Brinz/brim vehicle;   Drug: Prostaglandin analogue
Sponsor:   Alcon Research
Not yet recruiting - verified July 2015

Development of Rational Ways of Medical and Non-medical Treatment Methods for Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Drug: Xenical (Orlistat);   Dietary Supplement: "Analimentary detoxication"
Sponsors:   Republican Scientific Center for Emergency Medicine;   Institute Of Cardiology & Internal Diseases, Kazakhstan
Completed - verified July 2015

Magnetic Resonance Venography Pre- and Post-Treatment in Patients With Idiopathic Intracranial Hypertension

Condition:   Pseudotumor Cerebri
Intervention:   Other: Radiological Imaging
Sponsor:   Jai Shankar
Not yet recruiting - verified July 2015

Study to Evaluate the Pharmacokinetic Interaction Between Fimasartan and Atorvastatin in Healthy Male Volunteers

Condition:   Hypertension
Interventions:   Drug: Fimasartan;   Drug: Atorvastatin
Sponsors:   Boryung Pharmaceutical Co., Ltd;   Seoul National University Hospital
Completed - verified March 2015

Study to Evaluate the Pharmacokinetic Interaction and Safety After Multiple Oral Doses of Fimasartan/Amlodipine and Rosuvastatin in Healthy Male Subjects

Condition:   Hypertension
Interventions:   Drug: Fimasartan;   Drug: Amlodipine;   Drug: Rosuvastatin
Sponsors:   Boryung Pharmaceutical Co., Ltd;   Inje University
Completed - verified March 2015

Lipidomics Screening of Celecoxib in ex Vivo Human Whole Blood Assay - Part B

Condition:   Healthy
Interventions:   Drug: Celecoxib;   Drug: Placebo
Sponsors:   University of Pennsylvania;   Eli Lilly and Company
Active, not recruiting - verified July 2015

A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension

Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
Intervention:   Other: No Intervention
Sponsor:   Allergan
Completed - verified July 2015

Stress Management for High Blood Pressure

Condition:   Prehypertension
Interventions:   Behavioral: Mindfulness-Based Stress Reduction;   Behavioral: Stress Management Education;   Other: American Heart Association Recommended Self-Care
Sponsors:   Kent State University;   University of Pennsylvania;   Case Western Reserve University
Recruiting - verified July 2015

Effect of Isometric Handgrip Training on Cardiovascular Risk in Hypertensives

Condition:   Hypertension
Intervention:   Other: Isometric handgrip training
Sponsors:   University of Pernambuco;   Conselho Nacional de Desenvolvimento Científico e Tecnólogico - CNPQ;   Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.;   Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco
Recruiting - verified July 2015

Whole-body Vibration Physiotherapy in Kidney Transplantation

Condition:   Kidney Transplantation
Interventions:   Other: Stochastic whole body vibration (WBV) therapy - Physiotherapeutical intervention;   Other: Stochastic whole body vibration (WBV) therapy - Sham physiotherapeutical intervention
Sponsors:   University Hospital Inselspital, Berne;   Bern University of Applied Sciences
Recruiting - verified July 2015

Surrogate Markers of Portal Pressure

Conditions:   Portal Hypertension;   Cirrhosis
Interventions:   Procedure: HVPG;   Drug: Indocyanine Green Retention test;   Device: Liver stiffness measurement;   Device: Spleen stiffness measurement
Sponsor:   VA Connecticut Healthcare System
Recruiting - verified July 2015

Evaluation of CAF22 After Renal Transplantation

Conditions:   Kidney Transplantation;   Delayed Graft Function
Intervention:   Other: Blood and urine sampling
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified July 2015

Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic Malignancies

Conditions:   Acute Lymphoblastic Leukemia/Lymphoma;   Myelodysplasia;   Acute Myelogenous Leukemia;   Juvenile Myelomonocytic Leukemia;   Chronic Myelogenous Leukemia
Intervention:  
Sponsors:   Center for International Blood and Marrow Transplant Research;   Pediatric Blood and Marrow Transplant Consortium;   National Marrow Donor Program
Recruiting - verified July 2015

Cut Your Pressure Too: The Los Angeles Barbershop Blood Pressure Study

Condition:   Hypertension
Interventions:   Behavioral: BP measurement & pharmacy;   Behavioral: BP educational materials
Sponsors:   Cedars-Sinai Medical Center;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI);   The California Endowment;   University of California Los Angeles - Clinical and Translational Science Institute;   Lincy Foundation
Recruiting - verified July 2015

Magnesium Sulfate in Pregnancy and Postpartum

Condition:   Severe Pre-eclampsia With Postnatal Complication
Intervention:   Drug: Magnesium Sulfate
Sponsor:   Complejo Hospitalario Dr. Arnulfo Arias Madrid
Recruiting - verified July 2015

Dietary Counseling to Reduce Salt Intake in Patients With High Blood Pressure

Condition:   Hypertension
Interventions:   Behavioral: Dietary Counseling;   Other: Control: Standard Care
Sponsors:   Ottawa Hospital Research Institute;   The Ottawa Hospital Academic Medical Association
Not yet recruiting - verified July 2015

Safety and Performance Study of the Moderato System

Conditions:   Hypertension Resistant to Conventional Therapy;   Bradycardia;   Atrioventricular Block
Intervention:   Device: The Moderato System
Sponsor:   BackBeat Medical Inc
Active, not recruiting - verified July 2015

Usefulness of Extracorporeal Removal of sFLT-1 in Women With Very Early Severe Preeclampsia

Condition:   Preeclampsia
Intervention:   Device: Apheresis for extracorporal removal of sFlt-1
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified June 2015

Phase III Trial BI 695502 Plus Chemotherapy vs. Avastin® Plus Chemotherapy in Patients With Lung Cancer

Condition:   Carcinoma, Non-Small-Cell Lung
Interventions:   Drug: Chemotherapy;   Drug: BI 695502;   Drug: bevacizumab;   Drug: Chemotherapy
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Exploratory, 2-Part Study to Assess Pulsed Inhaled Nitric Oxide on Functional Pulmonary Imaging Parameters in Subjects With WHO Grp 3 Pulmonary Hypertension Associated With COPD on LTOT

Conditions:   Pulmonary Hypertension;   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: inhaled NO - 30 mcg/kg IBW/hr [4880 ppm];   Drug: inhaled NO - 25 mcg/kg IBW/hr [2440 ppm] - Seq 1;   Drug: inhaled NO - 25 mcg/kg IBW/hr [4880 ppm] - Seq 1;   Drug: inhaled NO - 25 mcg/kg IBW/hr [4880 ppm] - Seq 2;   Drug: inhaled NO - 25 mcg/kg IBW/hr [2440 ppm] - Seq 2
Sponsor:   Bellerophon
Not yet recruiting - verified July 2015

Acceptability and Efficacy of 'Fish Surimi Peptide' in Under Five Children Suffering From Moderate Acute Malnutrition

Condition:   Moderate Acute Malnutrition
Intervention:   Dietary Supplement: Fish surimi peptide
Sponsors:   International Centre for Diarrhoeal Disease Research, Bangladesh;   Suzuhiro Kamaboko Co., Ltd.,Japan
Recruiting - verified June 2015

A Phase 4 Study of Regorafenib in Metastatic Colorectal Cancer - Does Educating Physicians Change Patient Out Comes?

Condition:   Physician Education
Intervention:   Drug: Regorafenib (Stivarga, BAY 73-4506)
Sponsor:   Bayer
Recruiting - verified July 2015

Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection

Conditions:   Cirrhosis;   Hypertension;   Status;Splenectomy;   Venous Thrombosis
Interventions:   Drug: Warfarin;   Drug: Dipyridamole;   Drug: Aspirin;   Drug: Low Molecular Weight Heparin
Sponsor:   Yangzhou University
Recruiting - verified July 2015

Metformin in Kidney Disease

Conditions:   Chronic Kidney Disease;   Cardiovascular Disease;   Metabolic Syndrome
Interventions:   Drug: metformin;   Drug: Placebo
Sponsor:   Department of Veterans Affairs
Recruiting - verified July 2015

Tissue Sodium in Pre-hypertensive Patients

Condition:   Hypertension
Interventions:   Drug: Spironolactone;   Drug: Chlorthalidone;   Dietary Supplement: Diet;   Drug: Placebo
Sponsors:   Vanderbilt University;   American Heart Association
Recruiting - verified July 2015

GS-4997 in Adults With Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: GS-4997;   Drug: Placebo to match GS-4997
Sponsor:   Gilead Sciences
Recruiting - verified July 2015

Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy

Conditions:   Cirrhosis;   Hypertension;   Venous Thrombosis;   Status; Splenectomy
Interventions:   Drug: Warfarin;   Drug: Dipyridamole;   Drug: Aspirin;   Drug: Low Molecular Weight Heparin
Sponsor:   Yangzhou University
Recruiting - verified July 2015

Alcon Ex-PRESS™ Glaucoma Filtration Device in Japanese Patients

Condition:   Glaucoma
Intervention:   Device: Ex-PRESS™ Glaucoma Filtration Device, Model P50PL
Sponsor:   Alcon Research
Recruiting - verified July 2015

A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension

Conditions:   Liver Cirrhosis;   Hepatic Cirrhosis;   Portal Hypertension
Intervention:   Drug: IDN-6556
Sponsor:   Conatus Pharmaceuticals Inc.
Completed - verified May 2015

Cornell University-Micronutrient Initiative Calcium Supplementation Study

Condition:   Preeclampsia
Interventions:   Dietary Supplement: Regimen A calcium and iron/folic acid;   Dietary Supplement: Regimen B calcium and iron/folic acid
Sponsors:   Cornell University;   Kenya Ministry of Health;   University of Nairobi, Department of Obstetrics and Gynecology;   Micronutrient Initiative
Active, not recruiting - verified July 2015

Dietary Approaches to Stopping Hypertension (DASH) Mobile App Pilot

Condition:   Hypertension
Intervention:   Behavioral: DASH Mobile mhealth enhanced coaching
Sponsor:   Boston University
Recruiting - verified July 2015

Testing Tissue Sodium Stores in CAPD Patients—Aims 1 & 2

Condition:   End Stage Renal Disease
Intervention:  
Sponsors:   Vanderbilt University;   Baxter Healthcare Corporation
Recruiting - verified July 2015

The Significance of Urine UbA52 In the Diagnosis of Diabetic Nephropathy

Condition:   Diabetic Nephropathy
Intervention:  
Sponsors:   Hebei Medical University Third Hospital;   Sixth Affiliated Hospital, Sun Yat-sen University
Completed - verified July 2014

Low-dose Glucocorticoid Vasculitis Induction Study

Conditions:   Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis;   Microscopic Polyangiitis;   Wegener Granulomatosis
Interventions:   Drug: Rituximab;   Drug: Glucocorticoids
Sponsors:   Chiba University;   National Hospital Organization Chiba East Hospital
Recruiting - verified July 2015

24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension

Conditions:   Diabetes Mellitus, Type 2;   Hypertension
Interventions:   Drug: Empagliflizon low dose;   Drug: placebo;   Drug: Empagliflizon high dose
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified July 2015

Efficacy, Safety, and Tolerability of GS-4997 in Participants With Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: GS-4997;   Drug: Placebo to match GS-4997
Sponsor:   Gilead Sciences
Recruiting - verified July 2015

Fimasartan/Amlodipine Combination Phase III

Condition:   Essential Hypertension
Interventions:   Drug: Fimasartan and Amlodipine;   Drug: Fimasartan
Sponsors:   Boryung Pharmaceutical Co., Ltd;   Gachon University Gil Medical Center;   The Catholic University of Korea;   Kangbuk Samsung Hospital;   Kyungpook National University;   Keimyung University Dongsan Medical Center;   Korea University Guro Hospital;   Korea University Anam Hospital;   DongGuk University;   Dong-A University Hospital;   Pusan National University Hospital;   Seoul National University Bundang Hospital;   Seoul National University Hospital;   Asan Medical Center;   Pusan National University Yangsan Hospital;   Wonju Severance Christian Hospital;   Gangnam Severance Hospital;   Severance Hospital;   Ulsan University Hospital;   Inje University;   Inje University Haeundai Paik Hospital;   Chonnam National University Hospital;   Jeju National University Hospital;   Chungnam National University;   Hanyang University Seoul Hospital
Completed - verified July 2015

Treatment of Masked Hypertension

Conditions:   Masked Hypertension;   Hypertension;   Chronic Renal Insufficiency
Interventions:   Other: Antihypertensive medication intensification;   Other: Usual care
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified July 2015

Heart Health 4 Moms

Conditions:   Cardiovascular Disease;   Preeclampsia;   Hypertension;   Post-partum Weight Retention
Interventions:   Behavioral: Web-based educational and motivational modules;   Behavioral: AHA care guidelines and resources
Sponsors:   Brigham and Women's Hospital;   Patient Centered Outcome Research Institute
Recruiting - verified July 2015

Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (ADEMPAS, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified July 2015

Endothelin Receptor Function and Acute Stress

Condition:   Hypertension
Interventions:   Drug: Bosentan;   Drug: Placebo
Sponsors:   Georgia Regents University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2015

Evaluation of the Pulmonary Vascular Reactivity Test in Patients With Pulmonary Arterial Hypertension and a Cardiac Shunt

Condition:   Pulmonary Arterial Hypertension With Congenital Cardiac Shunt
Intervention:   Other: Pharmacological test of pulmonary endothelial
Sponsor:   Assistance Publique - Hôpitaux de Paris
Suspended - verified July 2015

Combined Trab+Trab Versus Combined Trab+Trab With Subconjunctival Implantation of Ologen for Primary Congenital Glaucoma

Condition:   Congenital Glaucoma
Interventions:   Device: Ologen Collagen Matrix;   Procedure: Combined trabeculotomy-trabeculectomy
Sponsors:   National Centre of Ophthalmology named after academician Zarifa Aliyeva;   Aeon Astron Europe B.V.
Active, not recruiting - verified July 2015

EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat(BAY63-2521)
Sponsor:   Bayer
Recruiting - verified July 2015

Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer

Condition:   Carcinoma, Hepatocellular
Interventions:   Drug: Everolimus;   Drug: Tacrolimus;   Drug: Myfortic;   Drug: CellCept
Sponsor:   Baylor Research Institute
Recruiting - verified July 2015

Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia

Condition:   Preeclampsia
Intervention:   Biological: Recombinant human antithrombin (ATryn)
Sponsor:   rEVO Biologics
Recruiting - verified July 2015

The IMPULSE Study: Pilot

Condition:   Chronic Heart Failure
Intervention:   Other: Remote Ischemic Conditioning (using Sphygmomanometer)
Sponsors:   Baylor College of Medicine;   Thoratec Corporation
Recruiting - verified July 2015

Bardoxolone Methyl Evaluation in Patients With Pulmonary Arterial Hypertension (PAH) - LARIAT

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Bardoxolone methyl;   Drug: Placebo
Sponsor:   Reata Pharmaceuticals, Inc.
Recruiting - verified July 2015

UAB Center of Research Translation (CORT) Project 2: The Effects of Urate Lowing Therapy (ULT) in Inflammation, Endothelial Function, and Blood Pressure

Conditions:   Pre-hypertension;   JNC 7 Stage I Hypertension
Interventions:   Drug: Allopurinol;   Drug: Placebo
Sponsors:   University of Alabama at Birmingham;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified July 2015

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

Conditions:   Ischemic Stroke;   Atrial Fibrillation;   Transient Ischemic Attacks;   Transient Cerebrovascular Events
Intervention:   Other: Biomarker blood draw
Sponsor:   Ischemia Care LLC
Recruiting - verified July 2015

Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia

Condition:   Hypertension
Interventions:   Drug: Ibuprofen;   Drug: Acetaminophen
Sponsor:   Complejo Hospitalario Dr. Arnulfo Arias Madrid
Completed - verified July 2015

A Prospective Randomized, Double-Blind, Placebo-Controlled Trial Comparing VitroGro® ECM to Placebo in Patients With Venous Leg Ulcers

Condition:   Venous Leg Ulcer
Interventions:   Drug: VitroGro® ECM;   Drug: Dulbecco's Phosphate Buffered Saline
Sponsor:   Tissue Therapies Ltd.
Not yet recruiting - verified July 2015

Intraventricular Drain Insertion: Comparison of Ultrasound-guided and Landmark-based Puncture of the Ventricular System

Conditions:   Hydrocephalus;   Intracranial Hypertension
Interventions:   Procedure: Ultrasound guided ventricular drain insertion;   Procedure: landmark-based ventricular drain insertion
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified July 2015

Galectin-3 Blockade in Patients With High Blood Pressure

Condition:   Hypertension
Intervention:   Dietary Supplement: Modified Citrus Pectin (MCP)
Sponsors:   Boston Medical Center;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2014

Non-interventional Study on Compliance of Inhaled Treatment With Ventavis in Patient With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Iloprost (Ventavis, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified July 2015

The Effects of Social Support and Oxytocin Administration on Physiological Stress Reactivity in Essential Hypertension

Condition:   Essential Hypertension
Interventions:   Drug: Syntocinon-Spray;   Drug: Placebo of syntocinon;   Behavioral: Social support
Sponsors:   University Hospital Inselspital, Berne;   University of Bern
Recruiting - verified July 2015

Prevention of Preeclampsia With Aspirin in Recipients of Donated Oocytes.

Condition:   Pre-Eclampsia
Interventions:   Drug: Acetylsalicylic acid;   Drug: Placebo
Sponsor:   Instituto de Investigacion Sanitaria La Fe
Recruiting - verified July 2015

Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-005)

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: MK-8892;   Drug: Placebo for MK-8892
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

Beraprost-314d Added-on to Tyvaso® (BEAT)

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Beraprost Sodium 314d Modified Release Tablets;   Drug: Placebo
Sponsor:   Lung Biotechnology PBC
Recruiting - verified July 2015

Trabeculectomy With Ologen Collagen Implant vs Trabeculectomy With Mitomycin C and Provisc in Steroid Induced Glaucoma

Condition:   Steroid Induced Glaucoma
Interventions:   Device: Ologen Collagen Matrix;   Drug: Mitomycin C (MMC) and Provisc
Sponsors:   National Centre of Ophthalmology named after academician Zarifa Aliyeva;   Aeon Astron Europe B.V.
Enrolling by invitation - verified July 2015

Regorafenib in Frail and/or Unfit for Chemotherapy Patients With Metastatic Colorectal Cancer

Conditions:   Colorectal Neoplasms;   Metastatic Disease
Intervention:   Drug: Regorafenib
Sponsors:   Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD);   Bayer
Active, not recruiting - verified July 2015

Flow MRI in Normal Pressure Hydrocephalus

Condition:   Normal Pressure Hydrocephalus
Intervention:   Other: Flow imaging
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified July 2015

Nurse-led Reminder Program for the Prevention of Cardiovascular Diseases

Conditions:   Hypertension;   Cardiovascular Disease
Intervention:   Behavioral: Nurse-led reminder through email.
Sponsor:   Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Completed - verified July 2015

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Condition:   Kidney Transplantation
Interventions:   Drug: Belatacept;   Drug: Tacrolimus;   Drug: Cyclosporine
Sponsor:   Bristol-Myers Squibb
Recruiting - verified March 2015

Observational Description of Compliance for the Daily Ventavis Use Via the Insight Program in Class III Pulmonary Arterial Hypertension Patients

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Ventavis (Iloprost, BAYQ6256)
Sponsor:   Bayer
Active, not recruiting - verified July 2015

Hormonal, Metabolic, and Signaling Interactions in PAH

Conditions:   Idiopathic Pulmonary Arterial Hypertension;   Heritable Pulmonary Arterial Hypertension;   Scleroderma Associated Pulmonary Arterial Hypertension;   Appetite Suppressant Associate PAH
Intervention:  
Sponsor:   Vanderbilt University
Recruiting - verified July 2015

EHR-Based Clinical Decision Support to Improve BP Management in Adolescents

Conditions:   Hypertension;   Pre Hypertension;   Obesity
Intervention:   Behavioral: Clinical Decision Support (CDS)
Sponsors:   HealthPartners Institute for Education and Research;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2015

Use of Intravitreal Aflibercept Injection for Neovascular Glaucoma

Condition:   Neovascular Glaucoma
Intervention:   Drug: Aflibercept
Sponsor:   University of Colorado, Denver
Recruiting - verified July 2015

Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis

Conditions:   Acidosis, Renal Tubular;   Nephrolithiasis;   Vacuolar Proton-Translocating ATPases
Intervention:   Drug: Furosemide-Fludrocortisone-Test (test for urinary acidification)
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified July 2015

Renal Stent Placement for the Treatment of Renal Artery Stenosis in Patients With Resistant Hypertension

Conditions:   Renal Artery Stenosis;   Hypertension, Renovascular
Intervention:   Device: iCAST™ Rx Stent System
Sponsor:   Atrium Medical Corporation
Recruiting - verified July 2015

Assessment of Risk in Chronic Airways Disease Evaluation

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Intervention:  
Sponsors:   Cardiff University;   GlaxoSmithKline
Active, not recruiting - verified July 2015

A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-8150 (MK-8150-002)

Conditions:   Hypertension;   Isolated Systolic Hypertension
Interventions:   Drug: MK-8150;   Drug: Placebo for MK-8150
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

Non-invasive Diagnosis of Portal Hypertension With Acoustic Radiation Force Impulse (ARFI)

Conditions:   Portal Hypertension;   Chronic Liver Disease
Intervention:   Device: ARFI ultrasound
Sponsor:   VA Connecticut Healthcare System
Recruiting - verified July 2015

Combination Therapy to Treat Sleep Apnea

Condition:   Sleep Apnea, Obstructive
Interventions:   Drug: Placebo pill;   Drug: Sedative;   Other: Room air;   Other: Oxygen
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified July 2015

Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability

Conditions:   Emphysema;   Chronic Obstructive Pulmonary Disease (COPD);   Cystic Fibrosis;   Pulmonary Fibrosis;   Bronchiectasis;   Sarcoidosis;   Pulmonary Hypertension;   Alpha-1 Antitrypsin Deficiency
Interventions:   Procedure: Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™;   Device: STEEN Solution™
Sponsors:   University of North Carolina, Chapel Hill;   Duke University;   National Heart, Lung, and Blood Institute (NHLBI);   Vitrolife;   XVIVO Perfusion
Recruiting - verified July 2015

A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)

Conditions:   Type 2 Diabetes;   Chronic Kidney Disease
Interventions:   Drug: Dulaglutide;   Drug: Insulin glargine;   Drug: Insulin lispro
Sponsor:   Eli Lilly and Company
Recruiting - verified July 2015

Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis

Condition:   Focal Segmental Glomerulosclerosis
Interventions:   Drug: RE-021 (Sparsentan);   Drug: Irbesartan
Sponsor:   Retrophin, Inc.
Recruiting - verified July 2015

Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives

Conditions:   Stroke;   Transient Ischemic Attack;   Hypertension
Intervention:   Drug: all approved antihypertensive drugs; all approved statins
Sponsors:   Istituto Auxologico Italiano;   European Society of Hypertension;   Chinese Hypertension League
Recruiting - verified July 2015

Anastrozole in Patients With Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Anastrozole;   Drug: Placebo
Sponsor:   University of Pennsylvania
Active, not recruiting - verified April 2015

Effect of Prophylactic Aqueous Suppression on Hyperencapsulation of Ahmed Glaucoma Valves

Condition:   Glaucoma
Intervention:   Drug: Aqueous Suppressant Eye Drops
Sponsors:   Credit Valley EyeCare;   Canadian Glaucoma Clinical Research Council
Recruiting - verified July 2015

Blood Vessel Study

Condition:   Endothelial Cell Function
Intervention:  
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Enrolling by invitation - verified July 2015

Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)

Conditions:   Prematurity;   Respiratory Insufficiency;   Pulmonary Hypertension;   Respiratory Distress Syndrome, Newborn
Interventions:   Drug: Aerosolized Normal Saline;   Drug: Inhaled PGE1
Sponsors:   NICHD Neonatal Research Network;   National Center for Research Resources (NCRR);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Terminated - verified July 2015

Doxazosin an a1 Antagonist for Alcohol Dependence

Conditions:   Alcohol Dependence;   Anxiety
Interventions:   Drug: Doxazosin;   Drug: Placebo
Sponsors:   Brown University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Completed - verified July 2015

Sleep Apnea in Early to Mid-Stage Alzheimer's Disease

Conditions:   Early Onset Alzheimer Disease;   Alzheimer Disease;   Obstructive Sleep Apnea Syndromes
Interventions:   Device: CPAP Treatment;   Device: No treatment
Sponsors:   Centre Hospitalier Universitaire de Saint Etienne;   Association Lyonnaise de Logistique Posthospitalière
Recruiting - verified July 2015

HYPAZ: Hypertension Induced by Pazopanib

Conditions:   Renal Cell Carcinoma;   Soft Tissue Sarcoma;   Glioblastoma;   Ovarian Cancer;   Cervical Cancer;   Breast Cancer;   Non-small Cell Lung Cancer;   Small Cell Lung Cancer;   Pancreatic Cancer;   Melanoma;   Gastrointestinal Cancer
Intervention:   Drug: Pazopanib
Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   University of Cambridge;   GlaxoSmithKline
Terminated - verified July 2015

Inhaled Iloprost in the Treatment of Patients With Pulmonary Hypertension up to 4 Years

Condition:   Pulmonary Hypertension
Intervention:   Drug: Ventavis inhaled (Iloprost, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified July 2015

Effectiveness of Adalimumab in Moderate to Severe Plaque Psoriasis Patients With Distinct Co-morbidities

Conditions:   Moderate to Severe Plaque Psoriasis;   Antibodies;   Monoclonals
Intervention:  
Sponsors:   AbbVie (prior sponsor, Abbott);   Raffeiner GmbH
Active, not recruiting - verified July 2015

Frequency and Origin of Dysnatremias in the Emergency Department

Conditions:   Hyponatremia;   Hypernatremia
Intervention:  
Sponsors:   University Hospital Inselspital, Berne;   Steering committee of the NCCR
Withdrawn - verified July 2015

Impact of Bariatric Surgery on Epicardial Adipose Tissue and on Myocardial Function

Condition:   Severely Obese Patients
Intervention:   Procedure: bariatric surgery
Sponsor:   Assistance Publique Hopitaux De Marseille
Completed - verified July 2015

Detecting Early Onset Pre-eclampsia and Use of Placental Growth Factor (PlGF) for Marker of Trisomy 21

Condition:   Pregnancy
Intervention:  
Sponsor:   OVO R & D
Terminated - verified July 2015

Effects of Iron on Exercise Capacity During Hypoxia

Condition:   Healthy Volunteers
Interventions:   Drug: Iron sucrose.;   Drug: Normal saline
Sponsor:   University of Oxford
Completed - verified July 2015

Study to Evaluate Hemodynamic Effect of Different Loading Doses of Precedex in Post-surgical Intensive Care Unit (ICU) Patients

Condition:   Intensive Care Unit
Intervention:   Drug: Dexmedetomidine
Sponsor:   Hospira, Inc.
Completed - verified July 2015

Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular Hypertension

Conditions:   Glaucoma;   Ocular Hypertension
Interventions:   Drug: Azarga (brinzolamide 1% / timolol 0.5%);   Drug: Cosopt (dorzolamide 2% / timolol 0.5%)
Sponsor:   Alcon Research
Completed - verified January 2012

Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)

Conditions:   Pulmonary Arterial Hypertension;   Vasodilation;   Vasoconstriction
Interventions:   Drug: Bosentan;   Drug: Sitaxsentan;   Drug: Placebo;   Biological: Endothelin-3
Sponsors:   University of Edinburgh;   Encysive Pharmaceuticals
Completed - verified July 2015

Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery

Conditions:   Primary Open Angle Glaucoma (POAG);   Cataract
Interventions:   Procedure: Cataract Surgery;   Device: CyPass Micro-Stent
Sponsor:   Transcend Medical, Inc.
Completed - verified July 2015

Clinical Trial of Vitamin D3 to Reduce Cancer Risk in Postmenopausal Women

Condition:   Cancer
Interventions:   Dietary Supplement: Vitamin D;   Dietary Supplement: Calcium
Sponsors:   Creighton University;   National Institutes of Health (NIH);   National Cancer Institute (NCI)
Active, not recruiting - verified July 2015

Safety and Efficacy of Daily CF101 Administered Orally in Subjects With Elevated Intraocular Pressure

Conditions:   Ocular Hypertension;   Glaucoma
Interventions:   Drug: CF101;   Drug: Placebo
Sponsor:   Can-Fite BioPharma
Recruiting - verified March 2014

Temporal Artery Biopsy vs ULtrasound in Diagnosis of GCA (TABUL)

Condition:   Giant Cell Arteritis
Interventions:   Procedure: Ultrasound of temporal and axillary arteries;   Procedure: Temporal artery biopsy
Sponsors:   University of Oxford;   University of Sheffield;   Southend University Hospital;   Nuffield Orthopaedic Centre NHS Trust;   Oxford University Hospitals NHS Trust;   The Leeds Teaching Hospitals NHS Trust;   University of Bristol;   London School of Hygiene and Tropical Medicine;   Medical Center for Rheumatology Berlin-Buch
Completed - verified July 2015

Study of the Effects of Iron on Lung Blood Pressure at High Altitude

Condition:   Hypertension, Pulmonary
Interventions:   Drug: Iron sucrose;   Drug: Normal saline
Sponsors:   University of Oxford;   National Center of Cardiology and Internal Medicine, Kyrgyzstan
Suspended - verified July 2015

The AVB Study: Prospective Study Comparing the Ahmed Valve and the Baerveldt Implant for Treating Refractory Glaucoma

Condition:   Glaucoma
Interventions:   Device: Ahmed FP7 Valve;   Device: Baerveldt-350 Tube
Sponsors:   Credit Valley EyeCare;   Glaucoma Research Society of Canada
Completed - verified July 2015

Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population

Conditions:   Hypertension;   Elderly;   Cardiovascular Mortality;   Cognitive Impairment;   Morbidity
Intervention:  
Sponsors:   Central Hospital, Nancy, France;   French Cardiology Society;   Boehringer Ingelheim;   Ministry of Health, France
Completed - verified July 2015

Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed)

Condition:   Hypertension
Interventions:   Drug: Hydrochlorothiazide (HCTZ);   Drug: Comparator: Placebo to HCTZ;   Drug: Isosorbide mononitrate (ISMN);   Drug: Comparator: Placebo to ISMN
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

BAY63-2521:Long-term Extension Study in Patients With Pulmonary Arterial Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified July 2015

Corneal Endothelium After Glaucoma Surgery

Conditions:   Glaucoma;   Corneal Damage;   Intraocular Pressure
Intervention:  
Sponsor:   Chungnam National University
Completed - verified July 2015

Long Term Effects of Erythrocyte Lysis

Conditions:   Sickle Cell Disease;   Hemolytic Anemia
Interventions:   Procedure: Clinical Evaluations;   Other: Laboratory Studies
Sponsor:   St. Jude Children's Research Hospital
Active, not recruiting - verified July 2015

FFA Hypertension and Inflammation in Lean and Obese Subjects

Conditions:   Diabetes;   Hypertension;   Obesity
Interventions:   Other: Intralipid 20%;   Other: Normal Saline;   Other: Oral fat load
Sponsors:   Emory University;   American Diabetes Association
Completed - verified July 2015

Kidney and Blood Pressure Changes in Patients Receiving Bevacizumab, Aflibercept, Sunitinib, or Cediranib for Cancer

Condition:   Unspecified Adult Solid Tumor, Protocol Specific
Interventions:   Other: laboratory biomarker analysis;   Other: pharmacological study
Sponsors:   University Health Network, Toronto;   National Cancer Institute (NCI)
Active, not recruiting - verified July 2015

Special Investigation For Long-Term Use Of Sildenafil (Regulatory Post Marketing Commitment Plan)

Condition:   Pulmonary Hypertension
Intervention:   Drug: SILDENAFIL
Sponsor:   Pfizer
Completed - verified July 2015

Comparison of Best Medical Treatment Versus Best Medical Treatment Plus Renal Artery Stenting

Condition:   Renal Artery Stenosis
Interventions:   Device: Dynamic Renal Stent plus Best Medical Treatment;   Drug: Best Medical Treatment
Sponsor:   Biotronik AG
Completed - verified July 2015

Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure

Conditions:   Infant, Newborn;   Respiratory Insufficiency;   Pulmonary Hypertension;   Respiratory Distress Syndrome, Newborn;   Streptococcal Infections
Intervention:   Drug: Inhaled Prostaglandin E1
Sponsors:   NICHD Neonatal Research Network;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Withdrawn - verified July 2015

Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study (0954-133)

Condition:   Hypertension and Left Ventricular Hypertrophy (Thickening of the Main Pumping Chamber of the Heart)
Interventions:   Drug: MK0954,   /Duration of Treatment : 5 Years;   Drug: Comparator : atenolol /Duration of Treatment : 5 Years
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

Obese Hypertension Study (0954-315)

Condition:   Hypertension
Interventions:   Drug: Comparator: losartan +/- HCTZ;   Drug: Comparator: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

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