High Blood Pressure

Clinical Trial Finder

Many patients with high blood pressure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Comparison of Tab.Labetalol and Tab.Nifedipine for Management of Postpartum Hypertension

Condition:   Postnatal Hypertension
Interventions:   Drug: Labetalol;   Drug: Nifedipine
Sponsor:   Dow University of Health Sciences
Not yet recruiting - verified April 2015

Efficacy of Spironolactone in Cameroonian Diabetic Patients With Resistant Hypertension

Conditions:   Hypertension, Resistant to Conventional Therapy;   Diabetes Mellitus
Interventions:   Drug: Low dose spironolactone;   Other: Routine intensification of antihypertensive treatment
Sponsors:   Sobngwi Eugene;   University of Yaounde 1
Completed - verified April 2015

Natural History of Noncirrhotic Portal Hypertension

Conditions:   Cystic Fibrosis;   Immunologic Deficiency Syndrome;   Turner Syndrome;   Congenital Hepatic Fibrosis;   Idiopathic Non-Cirrhotic Portal Hypertension
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified March 2015

3D Echocardiographic Assessment of RV Function in Patients Undergoing Pulmonary Endarterectomy

Condition:   Chronic Thromboembolic Pulmonary Hypertension
Intervention:   Procedure: Pulmonary endarterectomy
Sponsor:   Papworth Hospital NHS Foundation Trust
Not yet recruiting - verified April 2015

Local Heat Stress in Autonomic Failure Patients With Supine Hypertension

Conditions:   Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions:   Other: Passive heat stress;   Other: Control (non-heating)
Sponsor:   Vanderbilt University
Recruiting - verified April 2015

Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension

Condition:   Hypertension
Intervention:   Drug: Trimethaphan
Sponsor:   Vanderbilt University
Recruiting - verified April 2015

Strengthening Mental Health Care in Chronic Care Patients With Hypertension. A Cluster Randomised Control Trial

Conditions:   Depression;   Hypertension
Intervention:   Behavioral: PC101+Mental Health
Sponsors:   University of KwaZulu;   Department for International Development, United Kingdom
Not yet recruiting - verified April 2015

SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)

Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: Brinzolamide 1%/brimonidine 0.2% tartrate ophthalmic suspension;   Drug: Brinz/brim vehicle;   Drug: Prostaglandin analogue
Sponsor:   Alcon Research
Not yet recruiting - verified April 2015

Observational Study to Evaluate the Safety and Efficacy for Levacalm Tab. Versus Valsartan/Amlodipine Combination Therapy in Essential Hypertension Patients

Conditions:   Lower Leg Edema;   Orthostatic Hypertension
Interventions:   Drug: Levacalm;   Drug: Valsartan/amlodipine
Sponsor:   LG Life Sciences
Recruiting - verified April 2015

Sepsis Assessment in Belgian Emergency Rooms

Conditions:   Sepsis;   Shock, Septic;   Severe Sepsis
Intervention:  
Sponsor:   Axis Shield Diagnostics Ltd
Not yet recruiting - verified April 2015

The Effect of a Homoeopathic Complex on Blood Pressure in Refractory Hypertension

Condition:   Essential Hypertension
Interventions:   Other: 20% ethanol;   Other: Homoeopathic complex
Sponsor:   University of Johannesburg
Recruiting - verified April 2015

Effect of Ambulatory BP Monitoring on the CliniCal coUrse and RenAl ouTcomE of CKD

Conditions:   Chronic Kidney Diseases;   Renal Insufficiency, Chronic;   Albuminuria;   Hypertension
Intervention:   Device: Ambulatory blood pressure monitoring (ABPM)
Sponsors:   Seoul National University Hospital;   Kangbuk Samsung Hospital;   Severance Hospital;   Eulji General Hospital
Recruiting - verified April 2015

Olive Leaf Extract as Part of a Healthy Lifestyle in the Reduction of Blood Pressure

Condition:   Pre Hypertension
Interventions:   Dietary Supplement: Olive leaf extract;   Dietary Supplement: Placebo
Sponsor:   University of Reading
Not yet recruiting - verified April 2015

Post-Exercise Hypotension in Elderly Hypertensive Men

Condition:   Hypertension
Interventions:   Other: Aerobic exercise;   Other: Combined exercises;   Other: Control
Sponsors:   Hospital de Clinicas de Porto Alegre;   Federal University of Rio Grande do Sul
Recruiting - verified September 2014

Pilot Study Testing Feasibility of Health Screening at Farm Site

Conditions:   Diabetes Screening;   Hyperlipidemia Screening;   Hypertension Screening
Intervention:   Other: Worksite screening for DM, HTN and hyperlipidemia
Sponsor:   Mayo Clinic
Recruiting - verified April 2015

The CSF Shunt Entry Site Trial

Condition:   Hydrocephalus
Intervention:   Procedure: Ventriculoperitoneal shunt insertion surgery
Sponsors:   Baylor College of Medicine;   Patient Centered Outcome Research Institute;   University of Alabama at Birmingham;   University of British Columbia;   University of Pittsburgh;   University of Toronto;   University of Utah;   University of Washington;   Vanderbilt University;   Washington University School of Medicine;   Hydrocephalus Association
Recruiting - verified April 2015

Non-contrast Cardiac CT as a Risk Stratification Tool in Patients With Non-cardiac Chest Pain

Condition:   Coronary Artery Disease
Intervention:   Other: Non-contrast Cardiac CT scan
Sponsor:   University of Southern Denmark
Recruiting - verified April 2015

Whole-exome Sequencing in Childhood Obesity

Condition:   Childhood Obesity
Intervention:  
Sponsors:   National University, Singapore;   National Medical Research Council (NMRC), Singapore;   Health Promotion Board, Singapore;   Genome Institute of Singapore A*Star, Singapore
Not yet recruiting - verified April 2015

Prediction of Behavior

Condition:   Diabetes, Hypertension
Interventions:   Behavioral: Prediction mailing;   Behavioral: Commitment mailing;   Behavioral: Reminder;   Behavioral: Anonymity;   Behavioral: Identification
Sponsor:   University of Pennsylvania
Recruiting - verified April 2015

Integrated Population Program for Diabetic Kidney Disease

Conditions:   Diabetic Kidney Disease;   Uncontrolled Hypertension
Intervention:   Behavioral: Telehealth
Sponsors:   Duke University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified March 2015

A Trial in Stable Intermediate Coronary Lesions and Grey-zone FFR Values

Conditions:   Grey-zone Fractional Flow Reserve;   Intermediate Coronary Lesions;   Stable Angina;   Coronary Physiology
Interventions:   Procedure: PCI;   Drug: Optimal Medical Therapy
Sponsors:   Golden Jubilee National Hospital;   British Heart Foundation;   University of Glasgow
Not yet recruiting - verified March 2015

Renal Denervation Using the Vessix Renal Denervation System for the Treatment of Hypertension (REDUCE HTN:REINFORCE)

Condition:   Hypertension
Interventions:   Device: Renal Denervation (Vessix);   Device: Renal Angiography
Sponsor:   Boston Scientific Corporation
Enrolling by invitation - verified April 2015

Ketamine Infusion for Acute Sickle Cell crisiS in the Emergency Department (KISS)

Conditions:   Pain;   Sickle Cell Disorder
Interventions:   Drug: Normal saline;   Drug: Ketamine
Sponsor:   Billy Sin
Recruiting - verified April 2015

Phase I Dose Escalation Study to Investigate the Safety of ISTH0036 in Subjects With Glaucoma Undergoing Trabeculectomy

Condition:   Primary Open Angle Glaucoma
Interventions:   Drug: TGF-β2 antisense oligonucleotide;   Procedure: Trabeculectomy
Sponsor:   Isarna Therapeutics GmbH
Recruiting - verified April 2015

Japanese Phase 3 Study of Aflibercept in Neovascular Glaucoma Patients

Condition:   Glaucoma, Neovascular
Interventions:   Drug: Aflibercept (Eylea, BAY 86-5321);   Drug: Sham Injection
Sponsors:   Bayer;   Regeneron Pharmaceuticals
Recruiting - verified April 2015

Preventing Sickle Cell Kidney Disease

Conditions:   Anemia, Sickle Cell;   Sickle Cell Disease;   Kidney Disease;   Hypertension;   Proteinuria
Interventions:   Drug: Losartan;   Drug: Losartan
Sponsors:   University of Alabama at Birmingham;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2015

Retrospective Analysis of the Geriatric Patients Underwent Unilateral Inguinal Herniorrhaphy

Condition:   Inguinal Hernia
Intervention:   Procedure: local infiltration anesthesia and sedation
Sponsor:   Diskapi Teaching and Research Hospital
Completed - verified February 2015

Comparison of Single and Combination Diuretics in Low-Renin Hypertension

Condition:   Hypertension
Interventions:   Drug: Hydrochlorthiazide;   Drug: Amiloride;   Drug: Hydrochlorthiazide and Amiloride
Sponsors:   University of Cambridge;   University of Leicester;   University of Dundee;   University of Glasgow;   University of Edinburgh;   Imperial College London;   Barts & The London NHS Trust;   King's College London;   University of Birmingham
Active, not recruiting - verified April 2015

Stress Management for High Blood Pressure

Condition:   Prehypertension
Interventions:   Behavioral: Mindfulness-Based Stress Reduction;   Behavioral: Stress Management Education;   Other: American Heart Association Recommended Self-Care
Sponsors:   Kent State University;   University of Pennsylvania;   Case Western Reserve University
Not yet recruiting - verified April 2015

Oxfordshire Women and Their Children's Health

Conditions:   Pregnancy;   Pre-eclampsia;   Gestational Diabetes;   Depression;   Metabolic Disorders;   Pregnancy Induced Hypertension;   Cardiovascular Disorders
Intervention:  
Sponsors:   Oxford University Hospitals NHS Trust;   University of Oxford
Recruiting - verified April 2015

Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: Brinzolamide 10 mg/mL / Brimonidine 2 mg/mL fixed combination eye drops, suspension;   Drug: Brinzolamide 10 mg/mL eye drops, suspension;   Drug: Brimonidine 2 mg/mL eye drops, solution;   Drug: Vehicle
Sponsor:   Alcon Research
Recruiting - verified April 2015

ReAl-life Multicentre Survey Evaluating Stroke Prevention Strategies (RAMSES)

Conditions:   Thrombotic Stroke;   Atrial Fibrillation and Flutter
Intervention:  
Sponsor:   Muğla Sıtkı Koçman University
Recruiting - verified April 2015

Weight Loss Referral for Healthier Survivorship in Obese Stage I-II Endometrial Cancer Survivors or Atypical Hyperplasia

Conditions:   Complex Endometrial Hyperplasia With Atypia;   Stage IA Uterine Corpus Cancer;   Stage IB Uterine Corpus Cancer;   Stage II Uterine Corpus Cancer
Interventions:   Behavioral: Weight Loss Specialist;   Other: Quality-of-Life Assessment;   Other: Medical Chart Review
Sponsors:   Case Comprehensive Cancer Center;   National Cancer Institute (NCI)
Recruiting - verified April 2015

Acthar on Proteinuria in IgA Nephropathy Patients

Conditions:   IgA Nephropathy;   Proteinuria
Intervention:   Drug: Acthar 80 unit injection
Sponsor:   Baylor College of Medicine
Recruiting - verified April 2015

A Proof of Concept Study of Electrical Discharge Produced Nitric Oxide for Inhalation

Condition:   Hypertension, Pulmonary
Intervention:   Device: electrical pulsed plasma discharge synthesis of nitric oxide
Sponsor:   Massachusetts General Hospital
Recruiting - verified April 2015

An Observational Study to Describe the Effectiveness of Angiotensin Converting Enzyme Inhibitor and Calcium Channel Blocker Combination in the Management of Hypertensive Patients With Elevated Heart Rate and Type 2 Diabetes

Condition:   Hypertension
Intervention:  
Sponsors:   Abbott;   Monitor Medikal Araştırma ve Danışmanlık Tic.Ltd.Şti (MonitorCRO)
Recruiting - verified April 2015

Effects of Ketamine in the Acute Phase of Suicidal Ideation

Condition:   Suicidal Ideation
Interventions:   Other: Baseline evaluation;   Drug: 1st perfusion of ketamine;   Drug: 1st perfusion of saline;   Other: Follow-up between perfusions;   Drug: 2nd perfusion of ketamine;   Drug: 2nd perfusion of saline;   Other: Follow-up after perfusions
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Recruiting - verified April 2015

A Phase III Long-term Study of TAK-536TCH in Patients With Essential Hypertension

Condition:   Essential Hypertension
Intervention:   Drug: TAK-536TCH tablet, TAK-536CCB tablet, and HCTZ 12.5 mg tablet
Sponsor:   Takeda
Recruiting - verified April 2015

Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years

Condition:   PAH
Intervention:   Drug: oral treprostinil
Sponsor:   United Therapeutics
Recruiting - verified April 2015

A Phase 4 Study of Regorafenib in Metastatic Colorectal Cancer - Does Educating Physicians Change Patient Out Comes?

Condition:   Physician Education
Intervention:   Drug: Regorafenib (Stivarga, BAY 73-4506)
Sponsor:   Bayer
Recruiting - verified April 2015

Evaluate the Interest of the Pre-conceptional Endometrial Immune Profiling to Increase Birth Rates

Condition:   Reproductive Medicine
Interventions:   Other: No immune profiling;   Drug: endometrial immune profiling
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified April 2015

Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-angle Glaucoma or Ocular Hypertension

Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension
Interventions:   Drug: Bimatoprost sustained-release;   Other: Sham;   Drug: Timolol;   Drug: Timolol Vehicle (placebo)
Sponsor:   Allergan
Recruiting - verified April 2015

Study on the Impact of Patient Navigators on the Health Education and Quality of Life in Formerly Incarcerated Patients

Conditions:   HIV/AIDS;   Diabetes Mellitus;   Hypertension;   Substance Use
Intervention:   Behavioral: Patient Navigation
Sponsors:   St. Luke's-Roosevelt Hospital Center;   Patient Centered Outcome Research Institute;   Hunter College of The City University of New York
Recruiting - verified April 2015

A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension

Conditions:   Liver Cirrhosis;   Hepatic Cirrhosis;   Portal Hypertension
Intervention:   Drug: IDN-6556
Sponsor:   Conatus Pharmaceuticals Inc.
Recruiting - verified April 2015

Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases

Conditions:   COPD (With - Without Rehabilitation);   Diffuse Interstitial Lung Diseases;   Pulmonary Arterial Hypertension Primary or Secondary (Post Embolic .....);   Cystic Fibrosis of the Adult
Intervention:   Other: Cross sectional psychometric evaluation of a self-administered dyspnea questionnaire.
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Pr Joel COSTE, Hôpital Hôtel Dieu - Unité de Bio Statistiques et Epidémiologiques, Paris
Active, not recruiting - verified April 2015

To Investigate the Effect of Tart Montmorency Cherry Juice (Prunus Cerasus) on Vascular Function.

Condition:   Hypertension
Interventions:   Dietary Supplement: 60mL tart Montmorency cherry juice;   Other: Placebo
Sponsor:   Northumbria University
Completed - verified April 2015

AOP2014 in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.

Condition:   Polycythemia Vera
Intervention:   Drug: Pegylated-Proline-interferon alpha-2b
Sponsors:   AOP Orphan Pharmaceuticals AG;   PharmaEssentia (Co-Sponsor for USA)
Recruiting - verified April 2015

Azilsartan Medoxomil (TAK-491) Compared to Placebo in Korean Adults With Hypertension

Condition:   Hypertension
Interventions:   Drug: Azilsartan medoxomil;   Drug: Azilsartan medoxomil placebo
Sponsor:   Takeda
Recruiting - verified April 2015

What Effect Has Case Method Education to General Practitioners on Their Knowledge on COPD and on the Health of Their Patients With COPD?

Condition:   COPD
Interventions:   Behavioral: Case method education in COPD;   Behavioral: Traditional education in COPD
Sponsors:   Karolinska Institutet;   County council Dalarna
Recruiting - verified April 2015

Intramuscular Oxytocics: A Comparison Study of Intramuscular Carbetocin, Syntocinon and Syntometrine for the Third Stage of Labour Following Vaginal Birth

Condition:   Post Partum Haemorrhage
Interventions:   Drug: Carbetocin;   Drug: Syntocinon;   Drug: Syntometrine
Sponsors:   North Bristol NHS Trust;   Ferring Pharmaceuticals;   University of Bristol;   University of the West of England;   Royal United Hospital Bath NHS Trust;   Gloucester Hospitals NHS Trust;   University Hospitals Bristol NHS Foundation Trust
Recruiting - verified August 2014

Phase-II Study of the Use of PulmoBind for Molecular Imaging of Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Intervention:   Drug: PulmoBind
Sponsor:   Montreal Heart Institute
Recruiting - verified April 2015

Immunological Profile in Relation to Cardiac Geometry in Hypertension

Condition:   Immune System Profile During Hypertensive Cardiac Remodeling
Intervention:  
Sponsor:   Neuromed IRCCS
Recruiting - verified April 2015

A Compassionate Case Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Glaucoma Patients With Uncontrolled Intraocular Pressure to Avoid Surgical Intervention

Condition:   Glaucoma
Intervention:   Drug: Rho-Kinase Inhibitor (AR-12286)
Sponsor:   New York Glaucoma Research Institute
Active, not recruiting - verified April 2015

A Study to Assess the Effect of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Uncontrolled Advanced Glaucoma With Prior Failed Trabeculectomy or Tube Shunt

Condition:   Advanced Glaucoma
Intervention:   Drug: Rho-Kinase Inhibitor
Sponsor:   New York Glaucoma Research Institute
Active, not recruiting - verified April 2015

A Study to Assess the Effect of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Chronic Angle-closure Glaucoma

Condition:   Chronic Angle-closure Glaucoma
Intervention:   Drug: Rho-Kinase Inhibitor
Sponsor:   New York Glaucoma Research Institute
Active, not recruiting - verified April 2015

VTEval Project - Prospective Cohort Studies to Evaluate and Improve Diagnostics, Management Strategies and Risk Stratification in VTE

Conditions:   Venous Thromboembolism (VTE);   Deep Vein Thrombosis (DVT);   Pulmonary Embolism (PE)
Intervention:  
Sponsor:   Johannes Gutenberg University Mainz
Recruiting - verified April 2015

Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (ADEMPAS, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified April 2015

EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat(BAY63-2521)
Sponsor:   Bayer
Recruiting - verified April 2015

Comparison of Effect of Postoperative Cyclosporine A 2% Ophthalmic Emulsion and Betamethasone Eye Drop on Surgical Success of Trabeculectomy Procedure

Condition:   Glaucoma, Open Angle
Interventions:   Drug: Cyclosporine;   Drug: Betamethasone
Sponsor:   Mashhad University of Medical Sciences
Completed - verified April 2015

Azilsaltan Tablets (Azilva Tablets) Special Drug Use Surveillance "Hypertension Complicated by Diabetes "

Condition:   Hypertension
Intervention:   Drug: Azilsartan
Sponsor:   Takeda
Active, not recruiting - verified April 2015

A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and Spain

Condition:   Pulmonary Arterial Hypertension (PAH)
Intervention:   Drug: Macitentan
Sponsor:   Actelion
Recruiting - verified April 2015

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Condition:   Carotid Stenosis
Interventions:   Procedure: Carotid endarterectomy;   Device: Carotid stenting
Sponsors:   Thomas G. Brott, M.D.;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified April 2015

Computed Tomography and Biomarker Analysis in Diagnosing Coronary Artery Disease in Asymptomatic Patients Who Have Undergone Stem Cell Transplant

Conditions:   Cancer Survivor;   Diabetes Mellitus;   Hypertension
Interventions:   Procedure: computed tomography;   Other: cytology specimen collection procedure;   Other: laboratory biomarker analysis;   Other: questionnaire administration
Sponsors:   City of Hope Medical Center;   National Cancer Institute (NCI)
Completed - verified April 2015

Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Conditions:   Primary Open Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: T-2345;   Drug: Xalatan
Sponsor:   Nephron Pharmaceuticals Corporation
Completed - verified April 2015

A Cross-Sectional Survey to Evaluate Diabetes Management, Control, Complications, Psychosocial Aspects of Patients With Type 2 Diabetes in Bangladesh, Indonesia, Malaysia, Philippines, Sri Lanka and Vietnam

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Intervention:   Other: No treatment given
Sponsor:   Novo Nordisk A/S
Not yet recruiting - verified April 2015

Effects of Oral Sildenafil on Mortality in Adults With PAH

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: sildenafil citrate;   Drug: sildenafil citrate;   Drug: sildenafil citrate
Sponsor:   Pfizer
Recruiting - verified April 2015

Bardoxolone Methyl Evaluation in Patients With Pulmonary Arterial Hypertension (PAH) - LARIAT

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Bardoxolone methyl;   Drug: Placebo
Sponsor:   Reata Pharmaceuticals, Inc.
Recruiting - verified April 2015

Comparative PK PD Study in PAH Patients (Fox vs. I-Neb)

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: lloprost(Ventavis,BAYQ6252, 20 µg/mL);   Drug: lloprost(Ventavis,BAYQ6252, 10 µg/mL)
Sponsor:   Bayer
Active, not recruiting - verified April 2015

The Efficacy of Bariatric Surgery Compared to Medical Therapy in Controlling Type2 Diabetes Mellitus in Patients With Non Morbid Obesity.

Conditions:   Overweight;   Diabetes Type 2
Interventions:   Procedure: Laparoscopic Sleeve Gastrectomy;   Procedure: Laparoscopic Roux-en-Y Gastric Bypass;   Drug: Advanced Medical Therapy
Sponsor:   Hadassah Medical Organization
Recruiting - verified February 2015

Riociguat Clinical Effects Studied in Patients With Insufficient Treatment Response to Phosphodiesterase-5 Inhibitor

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified April 2015

An Open, Non-randomized Pilot Study on the Effect of Preservative Free Tafluprost (Saflutan® Augentropfen) in Patients With Ocular Hypertension or Primary Open Angle Glaucoma With an Uncontrolled Intraocular Pressure of 30 mmHg and More

Conditions:   Primary Open Angle Glaucoma;   Ocular Hypertension
Intervention:   Drug: Saflutan® 15 microgram/ml Augentropfen im Einzeldosisbehältnis
Sponsor:   Dr. Anton Hommer
Completed - verified April 2015

Effect and Safety of Marealis RPC (Refined Peptide Concentrate) in Mild or Moderate Hypertensive Subjects

Condition:   Prehypertension
Interventions:   Dietary Supplement: Marealis refined peptide concentrate;   Dietary Supplement: Placebo
Sponsors:   KGK Synergize Inc.;   Marealis AS
Recruiting - verified April 2015

Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery

Conditions:   Hypertension, Pulmonary;   Ventricular Dysfunction, Left
Intervention:   Drug: IK-3001
Sponsor:   INO Therapeutics
Completed - verified April 2015

Non-interventional Study on Compliance of Inhaled Treatment With Ventavis in Patient With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Iloprost (Ventavis, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified April 2015

Evaluation of Blood Pressure Reduction, Safety, and Tolerability of Canagliflozin in Patients With Hypertension and Type 2 Diabetes Mellitus on Stable Doses of Anti-hyperglycemic and Anti-hypertensive Agents

Conditions:   Diabetes Mellitus, Type 2;   Hypertension
Interventions:   Drug: Canagliflozin;   Drug: Placebo
Sponsor:   Janssen Scientific Affairs, LLC
Completed - verified April 2015

A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or Glaucoma

Conditions:   Exfoliation Syndrome;   Ocular Hypertension;   Open Angle Glaucoma
Intervention:   Drug: AR-12286
Sponsor:   Glaucoma Associates of New York
Completed - verified April 2015

GLORIA-AF Registry Program (Phase II/III)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2015

Functional and Structural Imaging for Glaucoma

Condition:   Glaucoma
Intervention:  
Sponsors:   Oregon Health and Science University;   National Eye Institute (NEI)
Recruiting - verified April 2015

Aliskiren Study of Safety and Efficacy in Senior Hypertensives

Condition:   Hypertension
Interventions:   Drug: Aliskiren;   Drug: Amlodipine;   Drug: Ramipril;   Drug: Hydrochlorothiazide
Sponsor:   Novartis Pharmaceuticals
Withdrawn - verified April 2015

11C-acetate/18Fluorodeoxyglucose-FDG PET/CT and Cardiac MRI in Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Interventions:   Drug: 11C-acetate;   Drug: [18F]Fluoro-2-deoxy-2-D-glucose;   Other: Cardiac MRI
Sponsors:   University of Pennsylvania;   Cardiovascular Medical Research and Education Fund;   Brigham and Women's Hospital;   University of Maryland;   Yale University;   Washington University School of Medicine
Recruiting - verified April 2015

Controlling and Lowering Blood Pressure With The MOBIUSHD™ (CALM-FIM_EUR)

Condition:   Hypertension
Intervention:   Device: MobiusHD
Sponsor:   Vascular Dynamics, Inc.
Recruiting - verified April 2015

Effect of Antihypertensive Agents Over Sleep Apnea

Conditions:   Hypertension;   Obstructive Sleep Apnea
Interventions:   Drug: Diuretics;   Drug: Calcium Channel Blockers
Sponsor:   Hospital de Clinicas de Porto Alegre
Recruiting - verified April 2015

Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patients

Conditions:   Liver Cirrhosis;   Portal Hypertension
Interventions:   Drug: Rifaximin + propranolol;   Drug: Propranolol + Placebo
Sponsor:   Yonsei University
Recruiting - verified April 2015

ACE Inhibitors Combined With Exercise for Seniors - Pilot Study

Conditions:   Hypertension;   Aging
Interventions:   Behavioral: Exercise;   Drug: ACE inhibitor + exercise;   Drug: Thiazide diuretic + exercise;   Drug: Angiotensin receptor blocker + exercise
Sponsors:   University of Florida;   American Heart Association
Recruiting - verified April 2015

An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension

Conditions:   Glaucoma;   Ocular Hypertension
Interventions:   Drug: bimatoprost 0.01%;   Drug: travatan 0.004%;   Drug: timolol 0.5%;   Drug: hypromellose 0.3%
Sponsor:   Allergan
Completed - verified April 2015

Abiraterone With Different Steroid Regimens for Side Effect Related to Mineralcorticoid Excess Prevention in Prostate Cancer Prior to Chemotherapy

Condition:   Prostate Cancer
Interventions:   Drug: Abiraterone Acetate;   Drug: Prednisone 5 mg twice daily;   Drug: Prednisone 5 mg once daily;   Drug: Prednisone 2.5 mg twice daily;   Drug: Dexamethasone 0.5 mg once daily
Sponsor:   Janssen Pharmaceutica N.V., Belgium
Recruiting - verified April 2015

Self-Management and Educational Support in Extremely Obese Patients Awaiting Bariatric Care

Condition:   Obesity
Intervention:   Behavioral: Weight Wise Community Modules
Sponsors:   University of Alberta;   Canadian Institutes of Health Research  (CIHR);   Alberta Innovates Health Solutions;   AHS Cancer Control Alberta
Active, not recruiting - verified April 2015

The Use of Near Infrared Spectroscopy (NIRS) to Estimate Intracranial Pressure (ICP)

Condition:   Intracranial Hypertension
Intervention:  
Sponsor:   University of Virginia
Recruiting - verified April 2015

Targeting the Right Ventricle in Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsors:   University of Pennsylvania;   The Cardiovascular Medical Research and Education Fund;   Brigham and Women's Hospital;   University of Maryland;   Yale University;   Washington University School of Medicine
Recruiting - verified April 2015

Controlling and Lowering Blood Pressure With The MOBIUSHD™

Condition:   Hypertension
Intervention:   Device: MobiusHD™
Sponsor:   Vascular Dynamics, Inc.
Recruiting - verified April 2015

Hypertension and Urine Protease Activity in Preeclampsia

Conditions:   Preeclampsia;   Hypertension;   Proteinuria;   Pregnancy
Interventions:   Dietary Supplement: Sodium;   Dietary Supplement: Placebo
Sponsors:   Odense University Hospital;   The Danish Council for Strategic Research;   Lundbeck Foundation
Recruiting - verified April 2015

Proton w/FOLFIRINOX-Losartan for Pancreatic Cancer

Condition:   Pancreatic Cancer
Interventions:   Drug: FOLFIRINOX;   Drug: Losartan;   Radiation: Proton Beam Radiation
Sponsors:   Massachusetts General Hospital;   National Cancer Institute (NCI)
Recruiting - verified April 2015

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Condition:   Kidney Transplantation
Interventions:   Drug: Belatacept;   Drug: Tacrolimus;   Drug: Cyclosporine
Sponsor:   Bristol-Myers Squibb
Recruiting - verified March 2015

Relation of Consummatory and Anticipatory Food Reward to Obesity

Conditions:   Weight Gain;   Food Habits
Intervention:  
Sponsors:   Oregon Research Institute;   National Institutes of Health (NIH)
Active, not recruiting - verified April 2015

Multicentric Observational Study on Quality of Life in Glaucoma

Condition:   Primary Open-angle Glaucoma
Intervention:  
Sponsor:   Mario Negri Institute for Pharmacological Research
Completed - verified April 2015

A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn

Condition:   Pulmonary Hypertension, Familial Persistent, of the Newborn
Interventions:   Drug: placebo;   Drug: iv sildenafil
Sponsor:   Pfizer
Recruiting - verified April 2015

Multi-electrode Radiofrequency Renal Denervation System Feasibility Study

Condition:   Uncontrolled Hypertension
Intervention:   Device: Medtronic Multi-electrode Radiofrequency (RF) Renal Denervation system
Sponsor:   Medtronic Vascular
Active, not recruiting - verified April 2015

Epigenomic Dysregulation in Preeclampsia-Associated Chronic Hypertension

Conditions:   Preeclampsia;   Hypertension;   Pregnancy Induced Hypertension
Intervention:  
Sponsor:   Ohio State University
Completed - verified April 2015

Helping Hypertensive Latinos to Improve Medication Adherence

Condition:   Hypertension
Intervention:   Behavioral: Adherence Intervention
Sponsors:   New York University School of Medicine;   American Heart Association
Recruiting - verified April 2015

Vitamin D and Preeclampsia

Conditions:   Vitamin D Deficiency Defined as Serum 25OHD < 75 Nmol/l or 30ng/ml;   Preeclampsia;   Neonatal Hypercalcemia;   Pregnancy
Intervention:  
Sponsor:   Assistance Publique - Hôpitaux de Paris
Active, not recruiting - verified April 2015

Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm Newborn

Conditions:   Preterm Birth;   Intra-uterine Growth Restriction;   Maternal Preeclampsia;   Bronchopulmonary Dysplasia
Intervention:   Other: Biological samples
Sponsor:   Assistance Publique - Hôpitaux de Paris
Active, not recruiting - verified April 2015

Single-arm Study of Symplicity™ Renal Denervation System in Patients With Uncontrolled HyperTensioN in India

Condition:   Adults With Uncontrolled Hypertension
Intervention:   Device: Symplicity renal denervation system
Sponsors:   Medtronic Vascular;   Medtronic
Terminated - verified April 2015

Prevention Trial to Achieve Cardiovascular Targets

Conditions:   Coronary Artery Disease;   Peripheral Arterial Disease;   Hyperlipidemia;   Hypertension;   Diabetes;   Prediabetes;   Obesity
Interventions:   Behavioral: Prevention Consult;   Behavioral: Consult & Behavioral Intervention
Sponsors:   New York University School of Medicine;   The Rainer Arnhold Foundation
Recruiting - verified April 2015

Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension

Conditions:   Pulmonary Arterial Hypertension;   Hypertension, Pulmonary
Intervention:   Drug: Sildenafil
Sponsor:   Pfizer
Recruiting - verified April 2015

Efficacy, Safety and Tolerability of Multiple Doses of Valsartan in Children With Hypertension With or Without CKD

Condition:   Pediatric Hypertension With or Without CKD
Interventions:   Drug: VAL489;   Drug: VAL489 matching placebo
Sponsor:   Novartis Pharmaceuticals
Recruiting - verified April 2015

Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis

Condition:   Focal Segmental Glomerulosclerosis
Interventions:   Drug: RE-021 (Sparsentan);   Drug: Irbesartan
Sponsor:   Retrophin, Inc.
Recruiting - verified April 2015

Eisenmenger Quality Enhancement Research Initiative

Condition:   Eisenmenger
Intervention:   Other: subjects with diagnosis of Eisenmenger Syndrome
Sponsors:   Actelion;   Canadian Heart Research Centre
Recruiting - verified April 2015

Factors Influencing the Positive Outcome of Bariatric Surgery for Morbidly Obese Patients

Conditions:   Morbid Obesity;   Diabetes;   Hypertension
Intervention:  
Sponsor:   Assuta Hospital Systems
Recruiting - verified March 2012

Fibrosis a New Pathological Actor in Adipose Tissue

Conditions:   Obesity;   Metabolic Diseases;   Fibrosis;   Body Weight
Intervention:   Procedure: biopsy
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified April 2015

Anastrozole in Patients With Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Anastrozole;   Drug: Placebo
Sponsor:   University of Pennsylvania
Active, not recruiting - verified October 2012

Effect of Renin-angiotensin System Blockers on Glomerular Filtration Rate in Patients With Hypertension, Type 2 Diabetes With Normoalbuminuria

Conditions:   Diabetes;   Hypertensive Disease
Interventions:   Drug: Renin-angiotensin system blockers;   Drug: non-renin angiotensin system blockers
Sponsor:   Hospital Authority, Hong Kong
Recruiting - verified April 2015

Impact of a Multidisciplinary Intensive Management Clinic on Outcomes in Multi-Ethnic Asian Incident Hemodialysis Patients

Condition:   Stage 5 Chronic Kidney Disease
Intervention:   Other: Multidisciplinary, intensive and collaborative care
Sponsor:   National University, Singapore
Recruiting - verified April 2015

Integrated Diagnostics Characterization of Right Ventricular Diastolic Flow Dynamics in Pulmonary Arterial Hypertension

Condition:   Pulmonary Hypertension
Intervention:  
Sponsors:   National Jewish Health;   Siemens Medical Solutions
Completed - verified April 2015

Cardiac Energetics and Function in Normal Human Ageing

Conditions:   Left Ventricular Function Systolic Dysfunction;   Left Ventricular Function Diastolic Dysfunction;   Ageing
Intervention:   Drug: Ramipril
Sponsor:   Newcastle-upon-Tyne Hospitals NHS Trust
Enrolling by invitation - verified April 2015

Faith-based Approaches to Treating Hypertension and Colon Cancer Prevention

Conditions:   Blood Pressure;   Colorectal Cancer
Interventions:   Behavioral: Motivational Interviewing;   Behavioral: Patient Navigation
Sponsors:   New York University School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified April 2015

Titrated Disease Management for Patients With Hypertension

Condition:   Hypertension
Interventions:   Behavioral: Booster/ low resource;   Behavioral: Booster/ low resource;   Behavioral: Medium/Level 1 resource intensity;   Behavioral: High/Level 2 resource intensity
Sponsor:   Department of Veterans Affairs
Active, not recruiting - verified April 2015

Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:  
Sponsors:   Columbia University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified April 2015

Effectiveness of Adalimumab in Moderate to Severe Plaque Psoriasis Patients With Distinct Co-morbidities

Conditions:   Moderate to Severe Plaque Psoriasis;   Antibodies;   Monoclonals
Intervention:  
Sponsors:   AbbVie (prior sponsor, Abbott);   Raffeiner GmbH
Recruiting - verified April 2015

Tight Hemodynamic Control in Patients Who Are Chronically on Metoprolol

Conditions:   Vascular Disease;   Hypertension;   Angina;   Cardiac Disease
Interventions:   Drug: Esmolol;   Drug: Metoprolol
Sponsors:   University Health Network, Toronto;   Baxter Healthcare Corporation
Terminated - verified April 2015

A Study of MK-7145 Compared to Placebo and Hydrochlorothiazide for Lowering Blood Pressure in Male Participants With Hypertension (MK-7145-009 AM1)

Condition:   Hypertension
Interventions:   Drug: MK-7145;   Drug: MK-7145;   Drug: Hydrochlorothiazide (HCTZ);   Drug: Placebo to MK-7145;   Drug: Placebo to HCTZ
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified April 2015

DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5%

Conditions:   Open Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: DE-111 ophthalmic solution;   Drug: Tafluprost ophthalmic solution 0.0015%;   Drug: Concomitant use of tafluprost ophthalmic solution 0.0015% plus timolol ophthalmic solution 0.5%
Sponsor:   Santen Pharmaceutical Co., Ltd.
Completed - verified July 2012

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Condition:   Open Angle Glaucoma or Ocular Hypertension
Intervention:   Drug: DE-111 ophthalmic solution
Sponsor:   Santen Pharmaceutical Co., Ltd.
Completed - verified February 2013

DE-111 Against Timolol Ophthalmic Solution 0.5%

Conditions:   Open Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: DE-111 ophthalmic solution;   Drug: Timolol ophthalmic solution 0.5%
Sponsor:   Santen Pharmaceutical Co., Ltd.
Completed - verified July 2012

ShuntCheck Versus Radionuclide in Evaluating Shunt Function in Symptomatic NPH Patients

Condition:   Hydrocephalus
Intervention:   Device: ShuntCheck test
Sponsors:   NeuroDx Development;   Sinai Hospital of Baltimore;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified April 2015

MK-0954E Study in Participants With Hypertension (MK-0954E-357)

Condition:   Hypertension
Interventions:   Drug: losartan potassium (+) hydrochlorothiazide (+) amlodipine besylate (MK-0954E);   Drug: Losartan potassium;   Drug: Amlodipine besylate;   Drug: Placebo to MK-0954E;   Drug: Placebo to losartan potassium;   Drug: Placebo to amlodipine besylate
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified April 2015

Therapeutic Targeting of Stress Factors in Ovarian Cancer Patients

Conditions:   Invasive Epithelial Ovarian Cancer;   Primary Peritoneal Carcinoma;   Fallopian Tube Cancer
Intervention:   Drug: Propranolol
Sponsor:   Washington University School of Medicine
Completed - verified April 2015

RCT of Effects of Device-guided Breathing on Ambulatory BP

Condition:   Hypertension
Interventions:   Behavioral: Device-guided breathing;   Behavioral: Device-guided breathing - used for 16 weeks;   Behavioral: Relaxation;   Device: RESPeRate;   Device: Sham RESPeRate
Sponsors:   Rutgers, The State University of New Jersey;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2015

Ranolazine and Pulmonary Hypertension

Conditions:   Angina;   Pulmonary Arterial Hypertension
Intervention:   Drug: Ranolazine
Sponsors:   Northwestern University;   Gilead Sciences
Completed - verified April 2015

Community-based Approaches to Treating Hypertension and Colon Cancer Prevention

Conditions:   Hypertension;   Colon Cancer
Interventions:   Behavioral: MINT;   Behavioral: Patient Navigation
Sponsors:   New York University School of Medicine;   Cornell University;   Wayne State University
Completed - verified April 2015

Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)

Condition:   Systemic Sclerosis-Associated Pulmonary Arterial Hypertension
Interventions:   Biological: Rituximab;   Other: Placebo
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified April 2015

Metabolic Surgery Versus Medical Management for Resolution of Type II Diabetes

Conditions:   Obesity;   Type 2 Diabetes Mellitus
Interventions:   Other: Laboratory evaluations, sleep study;   Other: Best Medical Management;   Procedure: Roux-en-Y gastric bypass surgery
Sponsors:   David Bradley MD;   Covidien
Completed - verified April 2015

Trial Using Motivational Interviewing Positive Affect and Self-Affirmation in Hypertension (TRIUMPH)

Condition:   Hypertension
Interventions:   Behavioral: Positive Affect/Self-Affirmation/Motivational Interviewing;   Behavioral: Educational and Behavioral
Sponsors:   Weill Medical College of Cornell University;   National Institute on Minority Health and Health Disparities (NIMHD)
Completed - verified April 2015

The PREVENTS Trial: The Preventing Recurrent Events in Veterans Navigating Transient Ischemic Attack (TIA) or Stroke Trial

Conditions:   Stroke;   Transient Ischemic Attack
Interventions:   Behavioral: tailored intervention;   Behavioral: attention placebo
Sponsor:   Narrows Institute for Biomedical Research
Completed - verified April 2015

Reduction of Night-time Blood Pressure in Pediatric Renal Transplant Recipients

Condition:   Hypertension Secondary to Kidney Transplant
Intervention:   Drug: New Medication: Enalapril, Isradipine, Propranolol
Sponsors:   North Shore Long Island Jewish Health System;   Children's Hospital of Philadelphia
Recruiting - verified April 2015

Clinical Trial on the Effects of Long Term Administration of 20% Albumin in the Cardiovascular and Renal Function, And Hepatic Hemodynamics in Advanced Patients With Cirrhosis and Ascites.

Conditions:   Cirrhosis;   Ascites
Intervention:   Drug: Albumin
Sponsors:   Joan Albert Arnaiz;   Hospital Clinic of Barcelona
Completed - verified April 2015

Nutrition and Exercise Intervention Study

Conditions:   Hypertension;   Dyslipidemia;   Diabetes;   Low Back Pain
Intervention:   Behavioral: physical activity
Sponsor:   National Institute of Health and Nutrition
Active, not recruiting - verified April 2015

Preventing Recurrent Vascular Events in Patients With Stroke or Transient Ischemic Attack

Conditions:   Ischemic Stroke;   Transient Ischemic Attacks
Interventions:   Drug: Antihypertensive agents and lipid lowering therapy;   Other: Usual Care
Sponsors:   University of Alberta;   Heart and Stroke Foundation of Canada;   Alberta Heritage Foundation for Medical Research
Completed - verified April 2015

A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma

Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
Interventions:   Drug: DuoTrav (travoprost-timolol ophthalmic drops);   Drug: Xalacom (latanoprost-timolol ophthalmic drops)
Sponsors:   Ophthalmic Consultants Centres, Canada;   Alcon Research
Completed - verified April 2015

Open Label Access Study Of Sildenafil In Adult Patients With Pulmonary Arterial Hypertension Completing A1481244 Study

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Sildenafil citrate
Sponsor:   Pfizer
Temporarily not available - verified April 2015

SCOT Scleroderma Treatment Alternative Registry (STAR Registry)

Conditions:   Scleroderma, Systemic;   Sclerosis
Intervention:   Drug: currently available therapy in the community
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting - verified April 2015

A Study to Assess the Efficacy and Safety of 20, 40, and 80mg of Sildenafil Three Times a Day in the Treatment of Pulmonary Arterial Hypertension

Condition:   Hypertension, Pulmonary
Interventions:   Drug: sildenafil;   Drug: sildenafil;   Drug: placebo;   Drug: sildenafil
Sponsor:   Pfizer
Completed - verified April 2015

A Study to Evaluate Self-esteem and Relationships in Males With Erectile Dysfuntion

Condition:   Erectile Dysfunction
Interventions:   Drug: sildenafil;   Drug: placebo
Sponsor:   Pfizer
Completed - verified April 2015

Evaluating the Genetic Causes and Progression of Cholestatic Liver Diseases (LOGIC)

Conditions:   Liver Diseases;   Alagille Syndrome;   Alpha 1-Antitrypsin Deficiency
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified April 2015

Long Term Treatment of End Stage Renal Disease Patients With Lanthanum Carbonate (Fosrenol)

Condition:   Hyperphosphatemia
Intervention:  
Sponsor:   Shire
Active, not recruiting - verified April 2014

Bevacizumab Versus Ranibizumab for Diabetic Retinopathy

Conditions:   Diabetic Retinopathy;   Diabetic Macular Edema;   Proliferative Diabetic Retinopathy
Interventions:   Drug: bevacizumab;   Drug: Ranibizumab
Sponsor:   Ursula Schmidt-Erfurth, M.D.
Completed - verified April 2015

Efficacy of Perindopril to Prevent Recurrence of Atrial Fibrillation in Patients With Essential Hypertension

Conditions:   Essential Hypertension;   Atrial Fibrillation
Intervention:   Drug: Perindopril
Sponsors:   Montreal Heart Institute;   Servier
Active, not recruiting - verified April 2015

Ambient Air Pollution, Preeclampsia, and Preterm Delivery

Conditions:   Preeclampsia;   Preterm Delivery
Intervention:  
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Completed - verified April 2015

Amlodipine/Atorvastatin Combination to Reduce the Health Risk of High Blood Pressure and High Cholesterol Levels

Conditions:   Hypertension;   Hyperlipidemia
Intervention:   Drug: Amlodipine/atorvastatin single pill
Sponsor:   Pfizer
Completed - verified April 2015

Clinical Utility of Caduet in Achieving Blood Pressure and Lipid Endpoints in a Specific Patient Population

Conditions:   Hypertension;   Dyslipidemia
Intervention:   Drug: Amlodipine/Atorvastatin
Sponsor:   Pfizer
Completed - verified April 2015

Scleroderma: Cyclophosphamide or Transplantation (SCOT)

Conditions:   Scleroderma, Systemic;   Sclerosis;   Autoimmune Disease
Interventions:   Procedure: Autologous stem cell transplantation;   Drug: Cyclophosphamide;   Drug: Antithymocyte globulin, equine;   Drug: Methylprednisolone;   Drug: Growth colony stimulating factor (G-CSF);   Radiation: Total body irradiation (TBI)
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting - verified April 2015

Effect Of Carvedilol Versus Metoprolol On Glycemic Control In Patients With Type II Diabetes And Hypertension

Condition:   Hypertension
Interventions:   Drug: carvedilol;   Drug: metoprolol
Sponsor:   GlaxoSmithKline
Completed - verified April 2015

Glycemic Control Of Carvedilol Versus Metoprolol In Patients With Type II Diabetes Mellitus And Hypertension

Condition:   Hypertension
Interventions:   Drug: carvedilol;   Drug: metoprolol
Sponsor:   GlaxoSmithKline
Completed - verified June 2012

Dietary Intervention Study for Hypertension (DISH)

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Hypertension;   Vascular Diseases
Interventions:   Behavioral: diet, sodium-restricted;   Behavioral: diet, reducing
Sponsors:   University of Mississippi Medical Center;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2000

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