High Blood Pressure

Clinical Trial Finder

Many patients with high blood pressure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Aerobic Exercise Training in Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Interventions:   Other: Upper extremity aerobic exercise training;   Other: Alternative upper extremity exercises
Sponsor:   Gazi University
Not yet recruiting - verified February 2015

A Parallel-Arm, Randomized, Dose-Ranging Study of ENV515 Travoprost Extended-Release (XR) in Subjects With Bilateral Ocular Hypertension or Early Primary Open-Angle Glaucoma

Condition:   Glaucoma and Ocular Hypertension
Interventions:   Drug: ENV515 Travoprost XR;   Drug: TRAVATAN Z
Sponsor:   Envisia Therapeutics
Recruiting - verified February 2015

Long Term Impact of Pediatric Acute Renal Injury in Severe Sepsis

Conditions:   Acute Kidney Injury;   Chronic Kidney Disease;   Hypertension
Intervention:  
Sponsor:   University of Florida
Not yet recruiting - verified February 2015

A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Amlodipine Besylate Monotherapy

Condition:   Essential Hypertension
Interventions:   Drug: Amlodipine 5mg;   Drug: Amlodipine 5mg, Candesartan cilexetil 16mg;   Drug: Amlodipine 10mg, Candesartan cilexetil 16mg
Sponsor:   CJ HealthCare Corporation
Recruiting - verified October 2014

A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Candesartan Cilexetil Monotherapy

Condition:   Essential Hypertension
Interventions:   Drug: Candesartan cilexetil 16mg;   Drug: Amlodipine 10mg, Candesartan cilexetil 16mg
Sponsor:   CJ HealthCare Corporation
Recruiting - verified October 2014

Ablation of the Pulmonary Artery With High Pulmonary Hypertension During Mitral Valve Surgery

Condition:   Pulmonary Hypertension
Interventions:   Procedure: Surgical ablation of ganglion plexus pulmonary artery.;   Procedure: mitral valve surgery
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified February 2015

Evaluation of Complex Renal Cyst With CEUS/Functional MRI Versus CT

Conditions:   Cystic Renal Diseases;   Kidney Neoplasms
Interventions:   Other: Blood/urine sampling;   Other: Conventional routine CT examination;   Other: Contrast-enhanced renal ultrasonography (CEUS);   Other: Functional MRI
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified February 2015

Self-screening of Cardiovascular Risk

Condition:   Risk Factor, Cardiovascular
Interventions:   Behavioral: CV-screening-1 plus personalized;   Behavioral: CV-screening-2 plus personalized;   Behavioral: CV-screening-1 plus standard;   Behavioral: CV-screening-2 plus standard
Sponsor:   Parc de Salut Mar
Not yet recruiting - verified February 2015

Effect of olmesaRtan on Walking distancE and quaLIty of lifE in Peripheral Artery Disease Patients With Hypertension Treated For Intermittent Claudication (RELIEF)

Condition:   Peripheral Artery Disease With Intermittent Claudication
Interventions:   Drug: Olmesartan;   Drug: other anti-hypertensive drug
Sponsor:   Yonsei University
Recruiting - verified February 2015

INTERVENCION Trial

Condition:   Blood Pressure, High
Interventions:   Drug: Hydrochlorothiazide;   Drug: Amlodipine;   Drug: Telmisartan
Sponsor:   Prevencion
Recruiting - verified February 2015

Preventing Sickle Cell Kidney Disease

Conditions:   Anemia, Sickle Cell;   Sickle Cell Disease;   Kidney Disease;   Hypertension;   Proteinuria
Interventions:   Drug: Losartan;   Drug: Losartan
Sponsor:   University of Alabama at Birmingham
Not yet recruiting - verified February 2015

Effect of Gymnema Sylvestre on Metabolic Syndrome and Insulin

Condition:   Metabolic Syndrome
Interventions:   Drug: Placebo;   Drug: Gymnema Sylvestre
Sponsor:   University of Guadalajara
Completed - verified February 2015

TIPS in Fundal Variceal Bleeding (the TFB Study)

Conditions:   Portal Hypertension;   Bleeding Gastric Varices
Intervention:   Device: Early TIPS
Sponsors:   Institut d'Investigacions Biomèdiques August Pi i Sunyer;   Hospital Clinic of Barcelona;   Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau;   Germans Trias i Pujol Hospital;   Hospital Universitario Ramon y Cajal;   Hospital del Mar
Not yet recruiting - verified February 2015

Optimizing Individual Nutrition in Preterm Very Low Birth Weight Infants

Conditions:   Infant, Premature, Diseases;   Infant, Small for Gestational Age
Interventions:   Dietary Supplement: Individualized Nutrition;   Dietary Supplement: Optimized nutrition
Sponsors:   University of Texas Southwestern Medical Center;   Children's Medical Center Dallas
Not yet recruiting - verified February 2015

Acromegaly & Sleep Apnoea

Condition:   Acromegaly
Intervention:  
Sponsor:   The Leeds Teaching Hospitals NHS Trust
Recruiting - verified February 2015

Genetic Testing and Counseling to Reduce Diabetic Complications

Condition:   Diabetic Complication
Interventions:   Behavioral: Personalized Risk Counselling;   Other: Normal usual care
Sponsor:   Chinese University of Hong Kong
Recruiting - verified February 2015

Stress Management for High Blood Pressure

Condition:   Prehypertension
Interventions:   Behavioral: Mindfulness-Based Stress Reduction;   Behavioral: Stress Management Education;   Other: Usual Care
Sponsors:   Kent State University;   University of Pennsylvania;   Case Western Reserve University
Not yet recruiting - verified February 2015

A Pilot Study: Defining Peripheral Endothelial Function in Portal Hypertensive Cirrhotic Patients

Conditions:   Portal Hypertension;   Cirrhosis
Intervention:  
Sponsor:   Eyal Ashkenazi
Not yet recruiting - verified February 2015

A Multi-center Trial of IMPaCT CHW Support for Chronically-ill Patients

Conditions:   Hypertension;   Diabetes;   Obesity;   Tobacco Dependence
Intervention:   Behavioral: IMPaCT
Sponsors:   University of Pennsylvania;   Patient Centered Outcome Research Institute
Active, not recruiting - verified January 2015

Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma

Condition:   Scleroderma
Interventions:   Drug: atorvastatin;   Drug: Placebo
Sponsors:   University of Pittsburgh;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified February 2015

Weight Loss Referral for Healthier Survivorship in Obese Stage I-II Endometrial Cancer Survivors or Atypical Hyperplasia

Conditions:   Complex Endometrial Hyperplasia With Atypia;   Stage IA Uterine Corpus Cancer;   Stage IB Uterine Corpus Cancer;   Stage II Uterine Corpus Cancer
Interventions:   Behavioral: Weight Loss Specialist;   Other: Quality-of-Life Assessment;   Other: Medical Chart Review
Sponsors:   Case Comprehensive Cancer Center;   National Cancer Institute (NCI)
Recruiting - verified February 2015

Stress Echocardiography Versus Exercise ECG in Women With Chest Pain

Condition:   Coronary Artery Disease
Interventions:   Procedure: Exercise ECG;   Procedure: Stress Echocardiography
Sponsor:   London North West Healthcare NHS Trust
Recruiting - verified February 2015

A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients

Condition:   Thermal Injury, Pain, Anxiety
Interventions:   Drug: Ketamine;   Drug: Placebo, Normal Saline
Sponsor:   University of Colorado, Denver
Withdrawn - verified February 2015

Study of Normal Hip and Lumbar Bone Marrow With Dynamic Contrast Enhancement Magnetic Resonance Imaging

Condition:   Bone Marrow
Intervention:   Other: MRI sequence
Sponsor:   University Hospital, Lille
Completed - verified February 2015

Cut Your Pressure Too: The Los Angeles Barbershop Blood Pressure Study

Condition:   Hypertension
Interventions:   Behavioral: BP measurement & pharmacy;   Behavioral: BP educational materials
Sponsors:   Cedars-Sinai Medical Center;   University of California, Los Angeles;   University of California, San Francisco;   Kaiser Permanente;   Charles Drew University of Medicine and Science;   University of Southern California
Recruiting - verified February 2015

Impact of Availability of Showerpatch for Patients With Intravenous Catheters

Conditions:   Cystic Fibrosis;   Pulmonary Hypertension;   Neoplasms
Interventions:   Device: Shower patch IV catheter protection;   Device: Conventional IV catheter protection
Sponsors:   Universitaire Ziekenhuizen Leuven;   BEDAL;   Remedus
Not yet recruiting - verified October 2014

Validation of New Tools for the Assessment of Cognitive Functions and Connectivity Network in Hypertensive Patients

Conditions:   Hypertension;   Cognitive Impairment
Intervention:  
Sponsor:   Neuromed IRCCS
Not yet recruiting - verified February 2015

Online CBT-I for High Blood Pressure

Conditions:   Hypertension;   Prehypertension;   Insomnia
Interventions:   Behavioral: Cognitive Behavioral Therapy;   Behavioral: Healthy Sleep Habits
Sponsors:   Emory University;   American Heart Association
Recruiting - verified February 2015

Chronic Hypertension and Pregnancy (CHAP) Project

Condition:   Hypertension
Interventions:   Other: Anti-hypertensive therapy;   Other: No to low dose anti-hypertensive therapy
Sponsors:   University of Alabama at Birmingham;   Columbia University;   Drexel University College of Medicine;   Rutgers, The State University of New Jersey;   Lehigh Valley Hospital;   Saint Peters University Hospital;   Christiana Care Health Services;   Washington University School of Medicine;   Duke University;   University of Texas Southwestern Medical Center;   The University of Texas Health Science Center, Houston;   Stanford University;   University of Pennsylvania;   The University of Texas, Galveston;   University of Utah;   Intermountain Health Care, Inc.;   University of California, San Francisco;   Johns Hopkins University;   University of Pittsburgh;   Ochsner Health System;   University of North Carolina, Chapel Hill;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified February 2015

Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Weight Heparin in Child-Pugh B Cirrhotic Patients: a Randomized Controlled Study

Condition:   Cirrhosis
Intervention:   Drug: Enoxaparine
Sponsor:   Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified October 2014

A Phase 4 Study of Regorafenib in Metastatic Colorectal Cancer - Does Educating Physicians Change Patient Out Comes?

Condition:   Physician Education
Intervention:   Drug: Regorafenib (Stivarga, BAY 73-4506)
Sponsor:   Bayer
Recruiting - verified February 2015

An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension

Condition:   Hypertension
Interventions:   Drug: Azilsartan Medoxomil;   Drug: Losartan;   Drug: Placebo for Azilsartan Medoxomil;   Drug: Placebo for Losartan
Sponsor:   Arbor Pharmaceuticals, Inc.
Recruiting - verified February 2015

HeartMate III™ IDE Clinical Study Protocol

Condition:   Advanced Refractory Left Ventricular Heart Failure
Interventions:   Device: HeartMate III LVAS;   Device: HeartMate II LVAS
Sponsor:   Thoratec Corporation
Recruiting - verified February 2015

Postpartum Hemorrhage Prevention in Patients With Preeclampsia (PHP3 Study)

Condition:   Preeclampsia
Intervention:   Drug: Oxytocin
Sponsor:   University of Colorado, Denver
Not yet recruiting - verified February 2015

Risk Assessment by Cardiovascular Biomarkers in Chronic Dialysis Patients

Condition:   Endstage Renal Disease
Intervention:  
Sponsor:   University Hospital, Basel, Switzerland
Not yet recruiting - verified February 2015

24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension

Conditions:   Diabetes Mellitus, Type 2;   Hypertension
Interventions:   Drug: Empagliflizon low dose;   Drug: placebo;   Drug: Empagliflizon high dose
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified February 2015

First-trimester Prediction of Preeclampsia

Conditions:   Preeclampsia;   Severe Preeclampsia;   Fetal Growth Restriction;   Preterm Birth
Intervention:  
Sponsors:   Centre Hospitalier Universitaire de Québec, CHU de Québec;   Canadian Institutes of Health Research  (CIHR);   Laval University
Recruiting - verified February 2015

Efficacy, Safety, and Tolerability of GS-4997 in Participants With Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: GS-4997;   Drug: Placebo to match GS-4997
Sponsor:   Gilead Sciences
Recruiting - verified February 2015

Comparison of Combigan BID Versus Simbrinza TID

Conditions:   Glaucoma;   Ocular Hypertension
Interventions:   Drug: Combigan BID;   Drug: Simbrinza TID
Sponsors:   Cornerstone Health Care, PA;   Allergan
Recruiting - verified February 2015

Medication Adherence and "True" Resistance in Patients With Resistant Hypertension

Conditions:   Hypertensive Disease;   Hypertension, Resistant to Conventional Therapy
Intervention:  
Sponsor:   Charite University, Berlin, Germany
Recruiting - verified February 2015

OPsumit USers Registry

Conditions:   Pulmonary Arterial Hypertension;   PAH
Intervention:   Drug: Opsumit (macitentan)
Sponsor:   Actelion
Recruiting - verified February 2015

Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (ADEMPAS, BAY63-2521)
Sponsor:   Bayer
Recruiting - verified February 2015

Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management

Conditions:   Overweight;   Obese
Interventions:   Device: LLLT;   Drug: Lorcaserin
Sponsor:   Mayo Clinic
Active, not recruiting - verified February 2015

EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat(BAY63-2521)
Sponsor:   Bayer
Recruiting - verified February 2015

Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-of-Care Setting

Condition:   Congestive Heart Failure
Intervention:   Device: Samsung LABGEO IVD-A20 CHF Test
Sponsors:   Samsung Electronics;   Nexus-Dx
Terminated - verified February 2015

Sarpogrelate Drug Interaction

Conditions:   Hypertension;   Peripheral Artery Disease
Interventions:   Drug: Sarpogrelate pretreatment;   Drug: Sarpogrelate;   Drug: Metoprolol
Sponsor:   Ajou University School of Medicine
Completed - verified February 2015

Pharmacogenomic Testing Of the Elderly To Reduce Morbidity

Condition:   Genetics of Drug Metabolism
Intervention:  
Sponsors:   General Genetics Corporation;   Syntactx
Recruiting - verified February 2015

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Condition:   Carotid Stenosis
Interventions:   Procedure: Carotid endarterectomy;   Device: Carotid stenting
Sponsors:   Thomas G. Brott, M.D.;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2015

Evaluation of a Decision Support Tool

Conditions:   Medication Adherence;   Hypertension;   Decision Making, Shared;   Patient-Centered Outcomes Research
Interventions:   Behavioral: Control;   Behavioral: Interview Only;   Behavioral: Interview plus decision support tool
Sponsors:   Brigham and Women's Hospital;   Patient Centered Outcome Research Institute;   Foundation for Informed Medical Decision Making
Active, not recruiting - verified February 2015

Effects of Oral Sildenafil on Mortality in Adults With PAH

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: sildenafil citrate;   Drug: sildenafil citrate;   Drug: sildenafil citrate
Sponsor:   Pfizer
Recruiting - verified February 2015

Understanding the Exercise-Hypertension Paradox

Condition:   Hypertension
Interventions:   Dietary Supplement: Oral Antioxidant;   Other: Exercise rehabilitation
Sponsor:   Department of Veterans Affairs
Recruiting - verified February 2015

MERIT-2: Macitentan in thE tReatment of Inoperable Chronic Thromboembolic Pulmonary Hypertension (OL)

Condition:   Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
Intervention:   Drug: Macitentan
Sponsor:   Actelion
Recruiting - verified February 2015

Role of Placental Growth Factor (PlGF) in the Management of Non-Severe Preeclampsia

Condition:   Pregnancy; Pre-eclampsia, Mild
Intervention:   Other: Measurement of PlGF
Sponsor:   Fetal Medicine Research Center, Spain
Recruiting - verified January 2014

MERIT-1: Macitentan in thE tReatment of Inoperable Chronic Thromboembolic Pulmonary Hypertension

Condition:   Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
Interventions:   Drug: Macitentan;   Drug: Placebo
Sponsor:   Actelion
Recruiting - verified February 2015

UAB Center of Research Translation (CORT) Project 2: The Effects of Urate Lowing Therapy (ULT) in Inflammation, Endothelial Function, and Blood Pressure

Conditions:   Pre-hypertension;   JNC 7 Stage I Hypertension
Interventions:   Drug: Allopurinol;   Drug: Placebo
Sponsors:   University of Alabama at Birmingham;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified February 2015

Non-interventional Multi-center Study on Patients Under Routine Treatment of Pulmonary Arterial Hypertension (PAH) With Inhaled Iloprost Using I-Neb as a Device for Inhalation

Condition:   Pulmonary Hypertension
Intervention:   Drug: Ventavis (Iloprost, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified February 2015

A Open Label Study to Assess the Long-term Safety, Tolerability and Efficacy of Ambrisentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Condition:   Hypertension
Intervention:   Drug: Ambrisentan 5 mg
Sponsor:   GlaxoSmithKline
Recruiting - verified February 2015

Renal Denervation in Patients After Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Arterial Hypertension
Interventions:   Procedure: Renal denervation;   Drug: Metoprolol;   Drug: Lisinopril
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified February 2015

Ambrisentan for Inoperable Chronic Thromboembolic Pulmonary Hypertension.

Condition:   Hypertension
Interventions:   Drug: Ambrisentan 5 mg;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Recruiting - verified February 2015

Early Detection and Prevention of Mild Cognitive Impairment Due to Cerebrovascular Disease

Conditions:   Cerebrovascular Disease;   Mild Cognitive Impairment
Intervention:   Behavioral: Heart Health Intervention
Sponsor:   Gregory Jicha, 323-5550
Recruiting - verified February 2015

Optimum Treatment for Drug-Resistant Hypertension

Condition:   Hypertension, Resistant to Conventional Therapy
Interventions:   Drug: Spironolactone;   Drug: Bisoprolol;   Drug: Doxazosin;   Drug: Placebo
Sponsors:   University of Cambridge;   British Heart Foundation
Active, not recruiting - verified February 2015

Uses of Immunosuppression Therapy in Patients With Liver Transplantation

Condition:   Evidence of Liver Transplantation
Intervention:  
Sponsor:   Chang Gung Memorial Hospital
Completed - verified February 2015

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Condition:   Kidney Transplantation
Interventions:   Drug: Belatacept;   Drug: Tacrolimus;   Drug: Cyclosporine
Sponsor:   Bristol-Myers Squibb
Recruiting - verified October 2014

Safety Study of PLX-PAD Cells to Treat Pulmonary Arterial Hypertension (PAH)

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: PLX-PAD
Sponsor:   United Therapeutics
Recruiting - verified February 2015

Observational Description of Compliance for the Daily Ventavis Use Via the Insight Program in Class III Pulmonary Arterial Hypertension Patients

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Ventavis (Iloprost, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified February 2015

Evaluation of the Safety and Tolerability of Nitric Oxide (NO) Via Inhalation to Subjects With Bronchiolitis

Condition:   Bronchiolitis
Interventions:   Drug: Nitric Oxide;   Drug: Placebo
Sponsors:   Advanced Inhalation Therapies  Ltd;   Soroka University Medical Center
Active, not recruiting - verified January 2015

Telemonitoring of Hypertensive Patients

Condition:   Hypertension
Intervention:   Other: Telemonitoring of self-measured blood pressure
Sponsor:   Katholieke Universiteit Leuven
Not yet recruiting - verified February 2015

Free DNA and Nucleosome Concentrations in Pathological Pregnancies

Conditions:   Pregnancy;   Venous Thrombosis;   Pulmonary Embolism;   Hypertension, Pregnancy-Induced;   Eclampsia;   HELLP Syndrome;   Pre-Eclampsia;   Fetal Death;   Placental Insufficiency
Interventions:   Biological: Bloodwork, baseline;   Biological: Blood work, Months 1 & 2;   Biological: Bloodwork, Months -1 to -6
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified February 2015

Intracranial Hypertension and Optic Nerve Sheath Diameter

Conditions:   Cerebral Stroke;   Cerebral Venous Thrombosis
Intervention:   Other: ONSD ultrasound
Sponsor:   Hospices Civils de Lyon
Recruiting - verified February 2015

Comparing Diurnal Fluctuations in Intra Ocular Pressure Measured in Same Day Versus Different Days in Glaucoma Patients

Condition:   Glaucoma
Intervention:  
Sponsor:   Carmel Medical Center
Completed - verified February 2015

Renal Denervation in Treatment Resistant Hypertension

Condition:   Hypertension
Intervention:   Device: Renal denervation using Symplicity Catheter system
Sponsor:   University of Erlangen-Nürnberg Medical School
Recruiting - verified February 2015

Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension

Conditions:   Pulmonary Arterial Hypertension;   Hypertension, Pulmonary
Intervention:   Drug: Sildenafil
Sponsor:   Pfizer
Recruiting - verified February 2015

Impact of Renal SympAthetic DenerVation on Chronic HypErtension

Condition:   Uncontrolled Hypertension
Intervention:   Device: Celcius Thermacool Catheter or Chilli II Cooled Ablation Catheter
Sponsor:   Vivek Reddy
Recruiting - verified February 2015

A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)

Conditions:   Type 2 Diabetes;   Chronic Kidney Disease
Interventions:   Drug: Dulaglutide;   Drug: Insulin glargine;   Drug: Insulin lispro
Sponsor:   Eli Lilly and Company
Recruiting - verified February 2015

A Comparison of the Perioperative Hemodynamic Effects of Remifentanil and Esmolol in Intracranial Surgery

Conditions:   Tachycardia;   Hypertension;   Myocardial Ischemia
Interventions:   Drug: Esmolol;   Drug: Remifentanil
Sponsor:   Diskapi Teaching and Research Hospital
Completed - verified December 2012

Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis

Condition:   Focal Segmental Glomerulosclerosis
Interventions:   Drug: RE-021 (Sparsentan);   Drug: Irbesartan
Sponsor:   Retrophin, Inc.
Recruiting - verified February 2015

Xeloxiri as First-line Treatment in Patients With Advanced Unresectable Pancreatic Adenocarcinoma

Condition:   Pancreatic Adenocarcinoma
Interventions:   Drug: Capecitabine;   Drug: Oxaliplatin;   Drug: Irinotecan
Sponsor:   The University of Hong Kong
Recruiting - verified February 2015

Renal Denervation for Management of Drug-Resistant Hypertension

Condition:   Hypertension
Intervention:   Procedure: Renal denervation
Sponsor:   Katholieke Universiteit Leuven
Recruiting - verified February 2015

Renal Nerve Ablation in Chronic Kidney Disease Patients

Conditions:   Hypertension;   Chronic Kidney Disease
Intervention:   Device: Simplicity Catheter
Sponsor:   University of Erlangen-Nürnberg Medical School
Recruiting - verified February 2015

Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH)

Condition:   Non-operable Chronic Thromboembolic Pulmonary Hypertension
Intervention:   Drug: Treprostinil sodium
Sponsor:   SciPharm SàRL
Recruiting - verified February 2015

Efficacy of Ventavis Used in Real-life Setting.

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Inhaled iloprost (Ventavis, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified February 2015

Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: inhaled prostacyclin;   Drug: inhaled prostacyclin;   Drug: prostacyclin;   Drug: subcutaneous and intravenous prostacyclin;   Drug: oral ERA;   Drug: oral PDE5 inhibitors
Sponsor:   United Therapeutics
Completed - verified February 2015

Long-Term Non-Interventional Latanoprost Study

Conditions:   Glaucoma;   Ocular Hypertension
Interventions:   Other: No intervention other than routine medical care;   Other: No intervention other than routine medical care
Sponsor:   Pfizer
Recruiting - verified February 2015

Metabolic Impact of Fructose Restriction in Obese Children

Conditions:   Obesity;   Metabolic Syndrome
Intervention:   Other: fructose restriction diet
Sponsors:   University of California, San Francisco;   Touro University
Active, not recruiting - verified February 2015

A Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)

Condition:   Hypertension, Pulmonary
Interventions:   Drug: ambrisentan;   Drug: tadalafil
Sponsors:   GlaxoSmithKline;   Gilead Sciences
Completed - verified January 2015

Atrial Fibrillation Registry for Ankle-brachial Index Prevalence Assessment: Collaborative Italian Study.

Conditions:   Atrial Fibrillation;   Peripheral Vascular Disease
Intervention:  
Sponsor:   University of Roma La Sapienza
Completed - verified February 2015

Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric Patients

Conditions:   Congenital Cataract;   Aphakic or Pseudophakic Glaucoma
Intervention:  
Sponsor:   Carmel Medical Center
Completed - verified February 2015

ACT-293987 in Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: ACT-293987
Sponsor:   Actelion
Active, not recruiting - verified February 2015

Selexipag (ACT-293987) in Pulmonary Arterial Hypertension, GRIPHON Trial

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Selexipag (ACT-293987);   Drug: Placebo
Sponsor:   Actelion
Completed - verified February 2015

Post Marketing Observational Study in Patients With Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: tadalafil
Sponsor:   Eli Lilly and Company
Completed - verified February 2015

Idiopathic Intracranial Hypertension Treatment Trial

Condition:   Idiopathic Intracranial Hypertension
Interventions:   Drug: Acetazolamide;   Drug: Placebo;   Behavioral: Formal weight loss counselling program
Sponsors:   St. Luke's-Roosevelt Hospital Center;   National Eye Institute (NEI);   University of Rochester;   University of Iowa;   University of California, Davis
Completed - verified January 2015

BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified February 2015

Respiratory and Autonomic Plasticity Following Intermittent Hypoxia

Condition:   Sleep Apnea Syndromes
Intervention:   Drug: Antioxidant cocktail
Sponsor:   Department of Veterans Affairs
Completed - verified February 2015

Cardiovascular Disease Study

Condition:   Spinal Cord Injury
Interventions:   Procedure: 2 hour Oral Glucose Tolerance Test;   Procedure: Fat Meal Test
Sponsors:   Department of Veterans Affairs;   Kessler Foundation
Recruiting - verified February 2015

Genetics of Type 2 Diabetes in West Africans

Conditions:   Hypertension;   Diabetes
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified November 2014

Clinical Evaluation of Low Sodium Peritoneal Dialysis (PD) Solution on Hypertensive Patients Treated With PD

Condition:   Chronic Kidney Failure
Intervention:   Drug: Solution for Peritoneal Dialysis
Sponsor:   Fresenius Medical Care Deutschland GmbH
Completed - verified September 2014

Impact of Multiple Doses of BAY63-2521 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Patients With Interstitial Lung Disease (ILD) Associated Pulmonary Hypertension (PH)

Condition:   Hypertension, Pulmonary
Intervention:   Drug: Riociguat (Adempas, BAY63-2521)
Sponsor:   Bayer
Active, not recruiting - verified February 2015

The Effects of Rimonabant, on Weight and Metabolic Risk Factors

Conditions:   Schizophrenia;   Schizoaffective Disorder;   Obesity;   Hypertension;   Smoking
Interventions:   Drug: Rimonabant;   Drug: Placebo
Sponsors:   University of Maryland;   National Institute on Drug Abuse (NIDA)
Terminated - verified February 2015

HALT Progression of Polycystic Kidney Disease (HALT PKD) Study A

Condition:   Kidney, Polycystic
Interventions:   Drug: Lisinopril and Placebo;   Drug: Lisinopril and Telmisartan;   Drug: Lisinopril and Telmisartan;   Drug: Lisinopril and Placebo
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Boehringer Ingelheim;   Merck Sharp & Dohme Corp.;   Polycystic Kidney Disease Foundation
Completed - verified February 2015

The Effect of Lifestyle Intervention Versus Gastric Bypass on Various Comorbidities in Morbidly Obese Subjects

Conditions:   Obstructive Sleep Apnea;   Diabetes Mellitus;   Hypertension
Interventions:   Procedure: Bariatric surgery;   Behavioral: Intensive lifestyle intervention
Sponsors:   The Hospital of Vestfold;   South-Eastern Norway Regional Health Authority
Completed - verified February 2015

Diagnosis of Pheochromocytoma

Condition:   Pheochromocytoma
Intervention:  
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2015

Diabetes and Heart Disease Risk in Blacks

Conditions:   Cardiovascular;   Diabetes;   Obesity;   Hypertension
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified February 2015

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