Women and Coronary Artery Disease

Clinical Trial Finder

Many women with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.


Condition:   Coronary Artery Disease
Interventions:   Drug: 3 months of dual antiplatelet therapy (DAPT);   Device: SYNERGY Stent System
Sponsor:   Boston Scientific Corporation
Recruiting - verified January 2016

Early Vascular Adjustments During Hypertensive Pregnancy

Conditions:   Hypertension, Pregnancy-Induced;   Pre-Eclampsia
Interventions:   Drug: Labetalol;   Drug: Nifedipine;   Drug: Methyldopa
Sponsor:   Maastricht University Medical Center
Recruiting - verified February 2016

Acute Vascular Response to Exercise in Women With Nonobstructive Coronary Artery Disease

Condition:   Nonobstructive Coronary Artery Disease
Intervention:   Other: Slow-paced walking
Sponsor:   University of Florida
Recruiting - verified February 2016

Pulmonary Artery Denervation for Treatment of Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Interventions:   Procedure: denervation;   Procedure: sham procedure
Sponsors:   Centre Hospitalier Universitaire de Nice;   Assistance Publique Hopitaux De Marseille;   University Hospital, Toulouse;   University Hospital, Grenoble;   Assistance Publique - Hôpitaux de Paris
Active, not recruiting - verified February 2016

Frailty in Elderly Patients Receiving Cardiac Interventional Procedures

Condition:   Frailty
Intervention:   Other: frailty evaluation
Sponsor:   University Hospital of Ferrara
Recruiting - verified September 2015

Trial of Dialysate Sodium in Chronic Hospitalized Hemodialysis Patients

Condition:   Intra-dialytic Hypotension
Interventions:   Drug: Lower dialysate sodium (138 mmol/L; using Renasol hemodialysis concentrate);   Drug: Higher dialysate sodium (142 mmol/L; using Renasol hemodialysis concentrate)
Sponsor:   Brigham and Women's Hospital
Recruiting - verified February 2016

Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass

Conditions:   Coronary Artery Bypass Grafting;   Mitral Valve Surgery;   Low Cardiac Output Syndrome
Interventions:   Drug: Levosimendan;   Drug: Placebo
Sponsor:   Tenax Therapeutics, Inc.
Recruiting - verified September 2015

Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer

Conditions:   Breast Cancer;   Breast Tumors;   Cancer of Breast
Interventions:   Drug: Metformin;   Drug: Atorvastatin;   Procedure: Breast surgery
Sponsor:   Columbia University
Recruiting - verified February 2016

Evaluating Safety and Effectiveness of Low-Dose Methotrexate at Reducing Inflammation in HIV-Infected Adults Taking Antiretroviral Medications

Condition:   HIV Infections
Interventions:   Drug: Methotrexate (MTX);   Drug: Placebo;   Dietary Supplement: Folic acid
Sponsor:   National Institute of Allergy and Infectious Disease (NIAID), National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified February 2016

Beraprost-314d Added-on to Tyvaso® (BEAT)

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Beraprost Sodium 314d Modified Release Tablets;   Drug: Placebo
Sponsor:   Lung Biotechnology PBC
Recruiting - verified November 2015

The Role of Biomarkers and Echocardiography in Prediction of Prognosis of Chronic Heart Failure Patients

Condition:   Heart Failure
Intervention:   Other: Observational study; no intervention.
Sponsors:   Erasmus Medical Center;   Medical Center Alkmaar
Recruiting - verified January 2016

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   New York University School of Medicine;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University
Recruiting - verified January 2016

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Conditions:   Infection;   Hypertension;   Pain;   Reflux;   Edema;   Hyperlipidemia;   Hypotension;   Hypercholesterolemia;   Sedation;   Anxiolysis;   Benzodiazepine Withdrawal;   Bipolar Disorder;   Autistic Disorder;   Schizophrenia;   Influenza Treatment or Prophylaxis;   Acute Decompensated Heart Failure;   Stable Angina;   Life-threatening Fungal Infections;   Nosocomial Pneumonia;   Community Acquired Pneumonia;   Acute Bacterial Exacerbation of Chronic Bronchitis;   Complicated Skin and Skin Structure Infections;   Uncomplicated Skin and Skin Structure Infections;   Chronic Bacterial Prostatitis;   Complicated Urinary Tract Infections;   Acute Pyelonephritis;   Uncomplicated Urinary Tract Infections;   Inhalational Anthrax (Post-Exposure);   Infantile Hemangioma;   Withdrawal;   Inflammation;   Bacterial Septicemia;   Cytomegalovirus Retinitis;   Herpes Simplex Virus;   Adenovirus;   Brain Swelling;   Airway Swelling;   Adrenal Insufficiency;   Anxiety;   Nausea;   Vomiting;   Convulsions;   Muscle Spasms;   Seizures;   Epilepsy;   Bartonellosis;   Brucellosis;   Cholera;   Plague;   Psittacosis;   Q Fever;   Relapsing Fever;   Rocky Mountain Spotted Fever;   Trachoma;   Tularemia;   Typhus Fever;   Bronchospasm;   Cardiac Arrest;   Hypersensitivity Reaction;   Cyanide Poisoning;   Acute Bacterial Sinusitis;   Bacterial Meningitis;   Sepsis;   Gastroparesis;   Opioid Addiction;   Migraines;   Headaches
Intervention:   Drug: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
Sponsors:   Daniel Benjamin;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   The EMMES Corporation;   OpAns, LLC
Recruiting - verified February 2016

Ventricular Tachycardia (VT) Ablation Versus Enhanced Drug Therapy

Condition:   Recurrent Ventricular Tachycardia
Interventions:   Procedure: Catheter Ablation;   Drug: Aggressive Antiarrhythmic Therapy (Amiodarone)
Sponsors:   John Sapp;   St. Jude Medical;   Biosense Webster, Inc.;   Canadian Institutes of Health Research (CIHR)
Completed - verified January 2016

Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)

Condition:   Thoracic Aortic Aneurysms
Intervention:   Device: Talent Thoracic Stent Graft System
Sponsors:   Medtronic Endovascular;   Medtronic
Active, not recruiting - verified January 2016

Letrozole in Treating Postmenopausal Women Who Have Received Hormone Therapy for Hormone Receptor-Positive Breast Cancer

Condition:   Breast Cancer
Interventions:   Drug: Letrozole;   Other: Placebo
Sponsors:   NSABP Foundation Inc;   National Cancer Institute (NCI);   Novartis
Active, not recruiting - verified February 2016

Enhancing Support for Women at Risk for Heart Disease

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Coronary Heart Disease Risk Reduction;   Diabetes Mellitus, Non-insulin Dependent
Interventions:   Behavioral: diet;   Behavioral: physical activity;   Behavioral: stress management;   Behavioral: smoking cessation
Sponsors:   Oregon Research Institute;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016

Lifestyle Management for Women With CHD and NIDDM

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Diseases;   Diabetes Mellitus, Non-insulin Dependent;   Postmenopause;   Diabetes Mellitus
Sponsors:   Oregon Research Institute;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016