Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Early Determinants of Multidimensional Outcome at School Age After Neonatal Arterial Ischemic Stroke

Condition:   Cerebral Infarction
Intervention:  
Sponsors:   Centre Hospitalier Universitaire de Saint Etienne;   Ministry for Health and Solidarity, France;   University Hospital of Saint-Etienne
Completed - verified July 2015

A Study of tDCS for Unilateral Neglect in Stroke Patients

Condition:   Stroke
Interventions:   Device: Transcranical direct current stimulator;   Behavioral: Visual inattention training
Sponsors:   Pusan National University School of Medicine;   Medwill hospital
Recruiting - verified July 2015

Characterizing Hemodynamic Compensation in Patients With Intracranial Stenosis

Conditions:   Stroke;   Intracranial Stenosis
Intervention:  
Sponsor:   Vanderbilt University
Recruiting - verified July 2015

Efficacy of Tablet-Based Social-Cognitive Interventions in Right Hemisphere Stroke and Frontotemporal Dementia

Conditions:   Frontotemporal Dementia;   Right Sided Cerebral Hemisphere Cerebrovascular Accident
Intervention:   Other: Brain HQ
Sponsors:   Johns Hopkins University;   University of California, San Francisco
Not yet recruiting - verified July 2015

Platelet Reactivity in Acute Non-disabling Cerebrovascular Events

Conditions:   Stroke;   Ischemic Attack, Transient
Interventions:   Drug: Ticagrelor and Acetylsalicylic acid;   Drug: Clopidogrel and Acetylsalicylic acid
Sponsors:   Ministry of Science and Technology of the People´s Republic of China;   Beijing Municipal Science & Technology Commission
Not yet recruiting - verified July 2015

The Effectiveness of Early Botulinum Toxin A Injection for Lower Limbs Spasticity in Subacute Stroke Adults

Conditions:   Stroke;   Muscle Spasticity
Intervention:   Drug: BoNT-A injection
Sponsor:   Sir Run Run Shaw Hospital
Recruiting - verified July 2015

mHealth Screening to Prevent Strokes

Condition:   Atrial Fibrillation
Interventions:   Device: iRhythm ZIO XT Patch;   Device: Wristband by Amiigo
Sponsors:   Scripps Translational Science Institute;   Janssen Scientific Affairs, LLC;   Aetna, Inc.
Not yet recruiting - verified July 2015

Very Intensive Variable Repetitive AmbulatioN Training

Condition:   Stroke
Intervention:   Behavioral: exercise
Sponsor:   Rehabilitation Institute of Chicago
Recruiting - verified July 2015

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center (CPC), Denver, Colorado, USA
Not yet recruiting - verified July 2015

Mobile Phones in Cryptogenic Stroke Patients Bringing Single Lead ECGs to Detect Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Ischemic Stroke;   Transient Ischemic Attack
Interventions:   Device: Single lead ECG device;   Device: 7-Day Holter monitor.
Sponsors:   Leiden University Medical Center;   Medical Center Haaglanden;   Groene Hart Ziekenhuis;   Herning Hospital;   Bronovo Hospital
Not yet recruiting - verified July 2015

Prospective Record Of the Use of Dabigatran in Patients With Acute Stroke or TIA

Conditions:   Brain Ischemia With Non-valvular Atrial Fibrillation;   Transient Ischemic Attack With Non-valvular Atrial Fibrillation
Intervention:  
Sponsor:   University Hospital, Essen
Recruiting - verified July 2015

Novel Biomarkers of Thrombotic Risk

Condition:   Myocardial Infarction
Intervention:  
Sponsors:   University of Vermont;   Janssen Research & Development, LLC
Recruiting - verified July 2015

Fluid Responsiveness Evaluation by AbdomiNal Compression in Kids Based on the STARLING Concept

Condition:   Circulatory Failure
Intervention:   Other: Observational study. No special intervention will be made
Sponsor:   Hopital Louis Pradel
Recruiting - verified July 2015

Selenium and Ischemic Stroke Outcome

Condition:   Ischemic Stroke
Interventions:   Drug: Selenium;   Drug: normal saline
Sponsor:   Mazandaran University of Medical Sciences
Not yet recruiting - verified July 2015

Clinical Reasoning Process of Physiotherapists When Observing Hemiplegic Gait

Condition:   Stroke
Intervention:   Other: Exploratory sequential design
Sponsor:   Technical University of Bern
Active, not recruiting - verified July 2015

Propensity to Develop Plasticity in the Parieto- and Cerebello-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing

Conditions:   Writer's Cramp;   Healthly Volunteers;   Cervical Dystonia
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - verified July 2015

Cardiovascular Response to Orthostatic Fractional Gravity

Condition:   Healthy Volunteers
Interventions:   Other: Parabolic flight;   Other: Cardiovascular measurements
Sponsor:   University Hospital, Caen
Recruiting - verified July 2015

Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Function

Conditions:   Persistent Atrial Fibrillation;   Congestive Heart Failure Due to Left Ventricular Systolic Dysfunction
Interventions:   Procedure: Atrial fibrillation catheter ablation;   Procedure: Rate control
Sponsors:   University of Turin, Italy;   Centro Cardiologico Monzino;   Humanitas Research Hospital IRCCS, Rozzano-Milan;   University of Padua;   Policlinico Casilino ASL RMB
Not yet recruiting - verified July 2015

In Vivo Characterization of Inflammation With Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging

Condition:   Multiple Sclerosis
Intervention:   Drug: Ferumoxytol
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified June 2015

Goal-directed Therapy in Endovascular Coiling of Cerebral Aneurysm Patients

Condition:   Cerebral Aneurysm
Intervention:   Device: Flotrac
Sponsor:   Lawson Health Research Institute
Not yet recruiting - verified July 2015

Speed of Processing Training in Traumatic Brain Injury

Conditions:   Traumatic Brain Injury;   Vascular Accident, Brain
Interventions:   Other: Brain Fitness Program;   Other: Weekly Telephone Contact
Sponsor:   New York University School of Medicine
Recruiting - verified July 2015

Functional Neural Connectivity at Rest as a Diagnostic Tool for Intolerance to Heat

Condition:   Functional Neural Connectivity
Intervention:   Device: MRI scans
Sponsor:   Sheba Medical Center
Not yet recruiting - verified July 2015

Exercise in Pregnancy Evaluative Controlled Study

Condition:   Pregnancy
Intervention:   Behavioral: Physical Exercise Participation
Sponsor:   Swansea University
Completed - verified July 2015

Decision Aids in Cerebral Aneurysm Treatment

Condition:   Cerebral Aneurysm
Interventions:   Behavioral: Option grid for cerebral aneurysm treatment;   Behavioral: Control
Sponsor:   Dartmouth-Hitchcock Medical Center
Not yet recruiting - verified July 2015

Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease

Conditions:   Irritable Mood;   Huntington's Disease
Interventions:   Drug: SRX246;   Drug: Placebo
Sponsors:   Azevan Pharmaceuticals;   National Institute of Neurological Disorders and Stroke (NINDS);   NeuroNEXT Network ;   Huntington Study Group
Not yet recruiting - verified July 2015

Transcranial Direct Current Stimulation and Robotic Therapy in Upper Limb Motor Recovery After Stroke

Condition:   Stroke
Interventions:   Device: tDCS plus wrist robot therapy;   Device: Sham tDCS plus wrist robot therapy
Sponsor:   Auxilium Vitae Volterra
Recruiting - verified July 2015

Natural History of Multiple Sclerosis and Its Mimickers

Conditions:   Neurologic Disorders;   Healthy Volunteers;   Multiple Sclerosis
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2015

Stroke Imaging Package Study

Conditions:   Atherosclerosis;   Stroke;   Infarction, Middle Cerebral Artery;   Vertebrobasilar Insufficiency;   Cerebral Small-vessel Disease;   Moyamoya Syndrome
Intervention:  
Sponsors:   Wei-Hai Xu;   Peking University First Hospital;   Peking Union Medical College Hospital;   General Hospital of Chinese Armed Police Forces;   Daping Hospital and the Research Institute of Surgery of the Third Military Medical University;   General Hospital of Shenyang Military Region;   Subei People's Hospital of Jiangsu Province;   Second Affiliated Hospital, School of Medicine, Zhejiang University;   Beijing Jishuitan Hospital;   Beijing Friendship Hospital;   Fuxing Hospital of Capital Medical University;   Fujian Medical University;   Jingan District Central Hospital of Shanghai (Jingan Branch of Huashan Hospital Affiliated to Fudan University);   First Hospital of Jilin University;   The First Affiliated Hospital of University of South China;   Qilu Hospital of Shandong University (Qingdao);   Tangshan Gongren Hospital;   Wuhan University;   Third Affiliated Hospital, Sun Yat-Sen University;   Renmin Hospital of Wuhan University;   Qilu Hospital;   Qingdao Municipal Hospital
Recruiting - verified July 2015

Closed Kinetic Chain Exercise Versus Russian Current Stimulation in Rehabilitation of Colles' Fracture.

Condition:   Distal Radius Fracture
Interventions:   Other: traditional exercise;   Other: Russian current stimulation;   Other: closed kinetic chain exercise
Sponsor:   October 6 University
Completed - verified July 2015

REducing Lung Congestion Symptoms Using thE V-wavE Shunt in Advanced Heart Failure

Condition:   Congestive Heart Failure
Intervention:   Procedure: V-Wave
Sponsor:   V-Wave Ltd
Not yet recruiting - verified July 2015

A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care

Conditions:   Pain;   Chronic Pain;   Mental Disorders;   Cardiovascular Diseases;   Diabetes Mellitus, Type 2;   Arthritis
Interventions:   Other: Unblinded to Genetic Testing Results;   Other: Blinded to Genetic Testing Results
Sponsor:   Proove Bioscience, Inc.
Recruiting - verified July 2015

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Recruiting - verified July 2015

The Miami Heart Study at Baptist Health South Florida

Condition:   Cardiovascular Disease
Intervention:  
Sponsors:   Baptist Health South Florida;   Quest Diagnostics;   University of California, Los Angeles
Recruiting - verified July 2015

WATCHMAN Implantation During Hybrid Ablation

Conditions:   Atrial Fibrillation;   Stroke
Intervention:   Device: WATCHMAN Device implantation
Sponsors:   Maastricht University Medical Center;   Boston Scientific Corporation
Recruiting - verified July 2015

Safety and Performance Study of the Edwards CENTERA-EU Self-Expanding Transcatheter Heart Valve

Condition:   Aortic Valve Disease
Intervention:   Device: Edwards CENTERA Self-Expanding Transcatheter Heart Valve
Sponsors:   Edwards Lifesciences;   Medstar Research Institute;   European Cardiovascular Research  Center;   University of British Columbia
Recruiting - verified July 2015

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Recruiting - verified July 2015

A Study of tDCS for Swallowing Difficulties in Stroke Patients

Condition:   Stroke
Interventions:   Device: Eldith DC-STIMULATOR;   Device: Sham Eldith DC-STIMULATOR
Sponsor:   Pusan National University School of Medicine
Recruiting - verified July 2015

FFP Versus PCC in Intracranial Hemorrhage

Conditions:   Intracranial Hemorrhage, Traumatic;   Intracranial Hemorrhage, Spontaneous
Interventions:   Drug: Four Factor Prothrombin Complex Concentrate;   Biological: Fresh Frozen Plasma
Sponsor:   University of Utah
Recruiting - verified April 2015

Feasibility of the Portable YouGrabber System

Conditions:   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Meningomyelocele;   Central Nervous System Diseases
Intervention:   Device: YouGrabber
Sponsor:   University Children's Hospital, Zurich
Completed - verified July 2015

Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization

Condition:   Cervical Intraepithelial Neoplasia
Interventions:   Drug: Bupivacaine;   Drug: Adrenaline
Sponsor:   Helse Fonna
Recruiting - verified July 2015

Valiant Mona LSA Feasibility Study

Condition:   Aortic Aneurysm, Thoracic
Intervention:   Device: Valiant Mona LSA Thoracic Stent Graft System
Sponsor:   Medtronic Endovascular
Recruiting - verified July 2015

Uninterrupted Dabigatran Etexilate in Comparison to Uninterrupted Warfarin in Pulmonary Vein Ablation (RE-CIRCUIT)

Condition:   Atrial Fibrillation
Interventions:   Drug: Warfarin;   Drug: Dabigatran Etexilate 150mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Electronic Alerts for Stroke Prevention in Patients With Atrial Fibrillation or Atrial Flutter

Conditions:   Atrial Fibrillation;   Stroke
Intervention:   Other: Computer Electronic Alert
Sponsors:   Brigham and Women's Hospital;   Daiichi Sankyo Inc.
Not yet recruiting - verified July 2015

Evaluation of the Effectiveness of Eliquis ® (Apixaban) Risk Minimization Tools in European Economic Area (EEA) Countries

Condition:   Stroke, Systemic Embolism, VTEt and VTEp
Intervention:  
Sponsors:   Bristol-Myers Squibb;   Pfizer
Not yet recruiting - verified July 2015

Timing of Coronary Angiography, Cardiac Surgery, and Adverse Renal and Cardiac Events (MARCE)

Conditions:   Acute Kidney Injury;   Renal Insufficiency
Intervention:   Procedure: cardiac surgery
Sponsor:   Baylor Research Institute
Recruiting - verified July 2015

Effects of a Positive Slope Treadmill Training in Individuals After Stroke. (Hemislope)

Condition:   Stroke
Intervention:   Other: Inclined treadmill training
Sponsor:   Centre d'Investigation Clinique et Technologique 805
Completed - verified July 2015

Effect of Brain-Computer Interfaced-Assisted Motor Imagery for Gait Retraining in Stroke Patients

Condition:   Stroke
Intervention:   Device: MI-BCI
Sponsors:   National University Hospital, Singapore;   National University Health System, Singapore;   Agency for Science, Technology and Research
Recruiting - verified July 2015

Changes in Brain Activity Associated With Upper Limb Motor Recovery

Condition:   Stroke
Intervention:   Device: tDCS
Sponsor:   National University Hospital, Singapore
Recruiting - verified July 2015

Brain Training System Using Electroencephalography (EEG) for Neurorehabilitation of Hand Function After Stroke

Condition:   Stroke
Intervention:   Procedure: Brain Computer Interface
Sponsor:   Chinese University of Hong Kong
Recruiting - verified July 2015

Study to Assess Impact of Dysport Injections Early After Stroke on Upper Limb Spasticity Progression

Conditions:   Stroke;   Upper Limb Spasticity
Interventions:   Drug: AbobotulinumtoxinA;   Drug: Placebo
Sponsor:   Ipsen
Recruiting - verified July 2015

Effects of Limb Ischemic Postconditioning in Young sICAS

Condition:   Stroke
Intervention:   Device: Remote ischemic postconditioning
Sponsors:   Xi’an Jiaotong University College of Medicine;   Xuanwu Hospital, Beijing
Recruiting - verified July 2015

Canadian Study of the MicroVention Flow Re-Direction (FRED) Endoluminal Device Stent System in the Treatment of Intracranial Aneurysms

Condition:   Intracranial Aneurysms
Intervention:   Device: FRED
Sponsor:   Centre hospitalier de l'Université de Montréal (CHUM)
Withdrawn - verified July 2015

Syncardia 50cc TAH-t as a Bridge to Transplant

Conditions:   Heart Failure, Right-Sided;   Cardiac Failure;   Heart Failure, Left-Sided
Intervention:   Device: SynCardia 50cc temporary Total Artificial Heart (TAH-t)
Sponsor:   SynCardia Systems. Inc.
Recruiting - verified July 2015

Cerebral Embolic Load in Patients Undergoing Surgical Aortic Valve Replacement: A Comparison of the Conventional With the Minimized Extracorporeal Circulation Technique Using Transcranial Doppler Ultrasound

Conditions:   Aortic Valve Stenosis;   Extracorporeal Circulation
Interventions:   Procedure: Minimized Extracorporeal Circulation (MECC);   Procedure: Conventional Extracorporeal Circulation (CECC)
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified July 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Study of Ticagrelor Versus Aspirin Treatment in Patients With Myocardial Injury Post Major Non-cardiac Surgery

Condition:   Myocardial Injury
Interventions:   Drug: ticagrelor;   Drug: aspirin
Sponsors:   The Cleveland Clinic;   AstraZeneca
Recruiting - verified July 2015

Role of USCOM in Adult Patients With Heart Failure

Conditions:   Acute Decompensated Heart Failure;   Congestive Heart Failure Compensated
Interventions:   Device: Ultrasonic cardiac output monitor;   Device: Echocardiography
Sponsors:   Chinese University of Hong Kong;   Cardiff and Vale University Health Board;   University Hospitals, Leicester
Recruiting - verified July 2015

Human Umbilical Cord Mesenchymal Stem Cell in Cerebral Hemorrhage Sequela

Condition:   Cerebral Hemorrhage
Intervention:   Biological: Human umbilical cord mesenchymal stem cells
Sponsors:   Shenzhen Hornetcorn Bio-technology Company, LTD;   The Fifth Affiliated Hospital of Guangzhou Medical University
Active, not recruiting - verified October 2014

Biomarker Signature of Stroke Aetiology Study: The BIOSIGNAL-Study

Condition:   Stroke, Acute
Intervention:  
Sponsors:   University of Zurich;   Swiss National Science Foundation
Recruiting - verified July 2015

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability

Conditions:   Chronic Troublesome Sialorrhea;   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Intellectual Disability
Interventions:   Drug: IncobotulinumtoxinA;   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified July 2015

Evaluation of SVV From NICOM as a Predictor of Fluid Responsiveness in Prone Position During Spine Surgery

Conditions:   Fluid Responsiveness;   Prone Position;   Non Invasive Cardiac Output Monitoring
Intervention:   Other: Fluid loading to evaluate fluid responsiveness
Sponsor:   Samsung Medical Center
Completed - verified July 2015

Evaluation of a New Calibrated Pulse Wave Analysis Method(EV1000™/volumeView™) for Cardiac Output Monitoring in Adult Liver Transplantation

Condition:   Liver Disease
Intervention:   Device: EV1000™/volumeView™
Sponsor:   Samsung Medical Center
Recruiting - verified July 2015

FAST Mapping During Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: FAST mapping and ablation;   Procedure: PVI
Sponsor:   University Health Network, Toronto
Recruiting - verified July 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Impact of Non-invasive Brain Stimulation, Associated With Upper Limb Robot-assisted Therapy, on Motor Recuperation

Condition:   Stroke
Intervention:   Device: tDCS (ELDITH) and RAT (REAplan)
Sponsors:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain;   University Hospital of Mont-Godinne
Recruiting - verified July 2015

SynCardia 70cc TAH-t for Destination Therapy (DT)

Conditions:   Life-threatening;   Biventricular Heart Failure;   Ineligible for Cardiac Transplant
Intervention:   Device: 70cc TAH-t for Destination Therapy
Sponsor:   SynCardia Systems. Inc.
Recruiting - verified July 2015

Implementation of Comprehensive Stroke Rehabilitation Therapy for Enhanced Quality of Life

Condition:   Stroke
Interventions:   Other: Experimental Group, Sub-Acute;   Other: Experimental Group, Chronic;   Other: Standard of Care, Sub-Acute;   Other: Standard of Care, Chronic
Sponsor:   University of Florida
Recruiting - verified July 2015

Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVR

Condition:   Peripheral Artery Disease (PAD)
Interventions:   Drug: Ticagrelor;   Drug: Comparator
Sponsors:   AstraZeneca;   CPC Clinical Research
Recruiting - verified July 2015

Healthy Lifestyles After Stroke

Conditions:   Stroke;   Apoplexy;   Cerebral Stroke;   Cerebrovascular Accident;   Cerebrovascular Accident, Acute;   Cerebrovascular Apoplexy;   Cerebrovascular Stroke;   CVA;   Stroke, Acute;   Vascular Accident, Brain
Intervention:   Behavioral: Healthy Lifestyle Training Program
Sponsors:   University of British Columbia;   Canadian Institutes of Health Research  (CIHR);   Heart and Stroke Foundation of Canada
Recruiting - verified July 2015

Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

Condition:   Subarachnoid Hemorrhage
Interventions:   Drug: desferrioxamine (DFO);   Drug: placebo
Sponsors:   Brigham and Women's Hospital;   Dr. Jeffrey Thomas Stroke Shield Foundation
Terminated - verified July 2015

Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve Replacement

Condition:   Aortic Stenosis
Interventions:   Device: Lotus Valve System;   Device: CoreValve Transcatheter Aortic Valve Replacement System
Sponsor:   Boston Scientific Corporation
Enrolling by invitation - verified July 2015

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Intracerebral Hemorrhage Deferoxamine Trial - iDEF Ttrial

Condition:   Intracerebral Hemorrhage
Interventions:   Drug: Deferoxamine Mesylate;   Drug: Placebo (for Deferoxamine Mesylate)
Sponsors:   Beth Israel Deaconess Medical Center;   Medical University of South Carolina;   National Institute of Neurological Disorders and Stroke (NINDS);   Massachusetts General Hospital;   Tufts Medical Center;   University of Massachusetts, Worcester;   University of Pennsylvania;   Johns Hopkins University;   University of Maryland;   Duke University;   University of North Carolina;   University of Florida;   Henry Ford Hospital;   Ohio State University;   St. Joseph's Hospital and Medical Center, Phoenix;   University of California, San Francisco;   Oregon Health and Science University;   Yale New Haven Health System Center for Healthcare Solutions;   University of Iowa;   Hartford Hospital;   The University of Texas Health Science Center, Houston;   Rhode Island Hospital;   Stanford University;   University of Washington;   University of Calgary, Foothills Hospital;   CHU de Québec - Hôpital de l'Enfant-Jésus;   University of Alberta;   Dalhousie University;   Rush University Medical Center;   University Hospital Case Medical Center;   Columbia University;   Weill Medical College of Cornell University;   New York University Langone Medical Center;   Mount Sinai Hospital, New York
Recruiting - verified July 2015

Longitudinal Study of Brain Amyloid imaGing in MEMENTO

Condition:   Alzheimer's Disease (AD) and Related Disorders
Interventions:   Drug: Flutemetamol (18F);   Drug: Florbetapir (18F)
Sponsors:   University Hospital, Bordeaux;   Fondation Plan Alzheimer;   GE-Healthcare corporation;   AVID corporation
Recruiting - verified July 2015

Transcatheter Aortic Valve Replacement System Pivotal Trial

Condition:   Aortic Valve Stenosis
Interventions:   Device: Direct Flow Medical Transcatheter aortic valve replacement;   Device: Medtronic CoreValve Transcatheter aortic valve replacement
Sponsor:   Direct Flow Medical, Inc.
Recruiting - verified July 2015

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Recruiting - verified April 2015

Comparison of Antithrombotic Treatments After Aortic Valve Replacement. Rivaroxaban: A New Antithrombotic Treatment for Patients With Mechanical Prosthetic Aortic Heart Valve.

Conditions:   Aortic Valve Disease;   Heart Valve Prosthesis Implantation;   Anticoagulants
Intervention:   Drug: Rivaroxaban
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified July 2015

Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders

Conditions:   Amyotrophic Lateral Sclerosis (ALS);   Myasthenia Gravis;   Myopathies;   Stroke;   Parkinson's Disease
Intervention:  
Sponsor:   Beth Israel Deaconess Medical Center
Recruiting - verified July 2015

Rivaroxaban for Antiphospholipid Antibody Syndrome

Condition:   Antiphospholipid Antibody Syndrome
Intervention:   Drug: Rivaroxaban
Sponsors:   St. Joseph's Healthcare Hamilton;   Heart and Stroke Foundation of Canada;   Bayer;   Hamilton Health Sciences Corporation;   Jewish General Hospital;   University of Alberta;   The Ottawa Hospital;   Queen Elizabeth II Health Sciences Centre
Recruiting - verified July 2015

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   The Cleveland Clinic
Recruiting - verified July 2015

Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

Condition:   Diabetes Type 2
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified November 2014

Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions

Conditions:   Chronic Troublesome Sialorrhea;   Parkinson's Disease;   Post-stroke;   Traumatic Brain Injury
Interventions:   Drug: IncobotulinumtoxinA (100 Units);   Drug: IncobotulinumtoxinA (75 Units);   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified July 2015

Efficacy Study of an Interactive Robot for the Rehabilitation of the Upper Limb in Acute Stroke Patients

Condition:   Acute Stroke
Interventions:   Other: Robotic-assisted therapy;   Other: Classical therapy
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Recruiting - verified July 2015

Edoxaban vs. Warfarin in Subjects Undergoing Cardioversion of Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Drug: edoxaban;   Drug: Enoxaparin;   Drug: Warfarin
Sponsors:   Daiichi Sankyo Inc.;   Covance;   Quintiles
Recruiting - verified July 2015

Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism)

Conditions:   Pulmonary Embolism;   Thromboembolism;   Thrombosis;   Venous Thrombosis;   Venous Thromboembolism
Interventions:   Drug: BAY 59-7939;   Drug: BAY 59-7939;   Drug: ASA
Sponsor:   Bayer
Recruiting - verified July 2015

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified July 2015

The IMPULSE Study: Pilot

Condition:   Chronic Heart Failure
Intervention:   Other: Remote Ischemic Conditioning (using Sphygmomanometer)
Sponsors:   Baylor College of Medicine;   Thoratec Corporation
Recruiting - verified July 2015

RESPOND Post Market Study

Condition:   Aortic Stenosis.
Intervention:   Device: Lotus Valve System
Sponsor:   Boston Scientific Corporation
Recruiting - verified July 2015

RELIEF Study: Lower Limb Pain Relief After Injection Cycles in Adults Suffering From Lower Limb Spasticity Following Stroke

Condition:   Lower Limb Spasticity
Intervention:   Drug: Botulinum Toxin Type A (BoNT-A) Injection
Sponsor:   Ipsen
Recruiting - verified July 2015

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

Conditions:   Ischemic Stroke;   Atrial Fibrillation;   Transient Ischemic Attacks;   Transient Cerebrovascular Events
Intervention:   Other: Biomarker blood draw
Sponsor:   Ischemia Care LLC
Recruiting - verified July 2015

Influence of Stroke on the Composition of Intestinal Microbiota

Conditions:   Stroke;   Transient Ischemic Attack (TIA)
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Prof. Dr. Ulrich Dirnagl, Experimental Neurology, Charité Berlin, Germany;   Dr. Christian Meisel, Medical Immunology, Charité Berlin, Germany;   PD Dr. Andreas Nitsche, Robert-Koch-Institut, Berlin, Germany
Recruiting - verified July 2015

Cardiovascular Outcomes Following Treatment With Ertugliflozin in Participants With Type 2 Diabetes Mellitus and Established Vascular Disease (MK-8835-004)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Active, not recruiting - verified July 2015

Adjusting Fluid Removal Based on Blood Volume in Hemodialysis: A Randomized Study

Conditions:   Intradialytic Hypotension;   End Stage Renal Failure on Dialysis
Interventions:   Device: BVM-UF biofeedback;   Device: Fresenius 5008 HD machine (Fresenius Medical Care, Bad Homburg, Germany)
Sponsor:   University of Calgary
Completed - verified July 2015

Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer

Conditions:   Rivaroxaban;   Cancer-associated Thrombosis;   Recurrence;   Bleeding
Intervention:   Drug: Rivaroxaban
Sponsors:   Seoul National University Hospital;   Korean Society of Hematology Thrombosis Working Party
Recruiting - verified July 2015

Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia

Conditions:   Oropharyngeal Dysphagia;   Deglutition Disorders
Intervention:   Device: Urostim I stimulation
Sponsor:   University Hospital, Rouen
Recruiting - verified July 2015

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

Evaluation of the Biological Response to Clopidogrel in Patients With Ischemic Stroke

Conditions:   Brain Ischemia;   Ischemic Attack
Intervention:   Drug: Clopidogrel
Sponsors:   Centre Hospitalier Universitaire de Saint Etienne;   Groupe de Recherche sur la Thrombose
Recruiting - verified July 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified July 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Acenocoumarol
Sponsor:   Bayer
Recruiting - verified July 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Phenprocoumon
Sponsor:   Bayer
Recruiting - verified July 2015

A Cohort of Outpatients From French Research Memory Centers in Order to Improve Knowledge on Alzheimer's Disease and Related Disorders

Condition:   Alzheimer's Disease (AD) and Related Disorders
Intervention:  
Sponsors:   University Hospital, Bordeaux;   Fondation Plan Alzheimer
Active, not recruiting - verified July 2015

Determining Optimal Post-Stroke Exercise (DOSE)

Conditions:   Cerebrovascular Accident;   Stroke;   Cerebral Infarction;   Brain Infarction;   Brain Ischemia;   Cerebrovascular Disorders;   Brain Diseases;   Central Nervous System Diseases;   Nervous System Diseases;   Vascular Diseases
Interventions:   Behavioral: Stroke Management Program (SMP);   Behavioral: Stroke Monitoring Program (SMonP);   Behavioral: Stroke Supplementary Program (SSP)
Sponsor:   University of British Columbia
Recruiting - verified July 2015

Dyslipidemia Management in Chinese Post Stroke Patients

Condition:   Brain Ischemia,Stoke
Intervention:  
Sponsor:   AstraZeneca
Completed - verified July 2015

Combining Armodafinil With Neuro-rehabilitation to Improve Neurological Recovery and Reduce Disability Post-Stroke

Conditions:   Stroke;   Cerebrovascular Accident;   Hemiparesis
Interventions:   Drug: Armodafinil;   Drug: Placebo
Sponsors:   Burke Rehabilitation Hospital;   Teva Pharmaceutical Industries
Completed - verified July 2015

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified July 2015

Cortical Recording and Stimulating Array Brain-Machine Interface

Conditions:   Tetraplegia;   Spinal Cord Injury;   Brainstem Stroke
Intervention:   Device: Implantation of CRS Arrays in the motor cortex and sensory cortex of the brain
Sponsors:   University of Pittsburgh;   Defense Advanced Research Projects Agency;   Department of Defense;   Johns Hopkins University
Recruiting - verified July 2015

Flow MRI in Normal Pressure Hydrocephalus

Condition:   Normal Pressure Hydrocephalus
Intervention:   Other: Flow imaging
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified July 2015

Study Of Diabetic Nephropathy With Atrasentan

Condition:   Diabetic Nephropathy
Interventions:   Drug: Atrasentan;   Drug: Placebo
Sponsor:   AbbVie
Recruiting - verified July 2015

GLP-1 and Hypoglycemia

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Glucagon-Like Peptide- 1 (GLP-1) infusion;   Other: Placebo Comparator: Saline Infusion
Sponsor:   University of Maryland
Recruiting - verified July 2015

Neuropsychological and Brain Medical Imaging Study in Patients With Brain Damage

Conditions:   Cerebrovascular Disorders;   Brain Lesions;   Degenerative Diseases;   Developmental Pathology
Interventions:   Behavioral: Neuropsychological testing;   Other: MRI
Sponsor:   University Hospital, Rouen
Recruiting - verified July 2015

Vascular Events In Surgery patIents cOhort evaluatioN - Cardiac Surgery

Conditions:   Vascular Death;   Myocardial Infarction;   Stroke;   Cardiac Surgery
Intervention:  
Sponsors:   Population Health Research Institute;   Abbott Diagnostics Division
Recruiting - verified July 2015

Asymmetrical Gait Training After Pediatric Stroke

Conditions:   Stroke;   Hemiplegia
Interventions:   Behavioral: Conventional physical therapy;   Behavioral: Asymmetrical gait training
Sponsor:   Children's Hospital of Philadelphia
Recruiting - verified July 2015

Cardiogenesis Transmyocardial Revascularization Registry

Condition:   Class IV Angina
Intervention:  
Sponsor:   Cardiogenesis Corporation, a wholly-owned subsidiary of CryoLife, Inc.
Completed - verified July 2015

Targeted Management Intervention for African-American Men With TIA or Stroke

Conditions:   Stroke;   Transient Ischemic Attack (TIA)
Intervention:   Behavioral: Psychoeducation
Sponsors:   Case Western Reserve University;   National Institute of Nursing Research (NINR)
Active, not recruiting - verified July 2015

A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: rivaroxaban 2.5 mg;   Drug: rivaroxaban 15 mg;   Drug: rivaroxaban 10 mg;   Drug: aspirin (ASA);   Drug: vitamin K antagonist (VKA);   Drug: clopidogrel;   Drug: prasugrel;   Drug: ticagrelor
Sponsors:   Janssen Scientific Affairs, LLC;   Bayer
Recruiting - verified July 2015

Preoperative Volume Substitution in Elective Surgery Patients

Conditions:   Hemodynamic Instability;   Hypovolemia;   Anesthesia
Interventions:   Other: Volume;   Other: Control
Sponsor:   Philipps University Marburg Medical Center
Completed - verified July 2015

Sickle Cell Disease - Stroke Prevention in Nigeria Trial

Conditions:   Sickle Cell Anemia;   Sickle Cell Disease;   Stroke
Intervention:   Drug: Hydroxyurea
Sponsors:   Vanderbilt University;   National Institutes of Health (NIH);   National Institute of Neurological Disorders and Stroke (NINDS);   Aminu Kano Teaching Hospital
Active, not recruiting - verified July 2015

A Pilot Study of Minocycline in Intracerebral Hemorrhage Patients

Condition:   Intracerebral Hemorrhage
Intervention:   Drug: Minocycline
Sponsors:   Georgia Regents University;   American Heart Association
Recruiting - verified July 2015

Wolman/CESD Natural History Chart Review and Longitudinal Follow-Up

Conditions:   Wolman Disease;   Cholesterol Ester Storage Disease;   Acid Cholesteryl Ester Hydrolase Deficiency, Type 2
Intervention:   Other: There are no interventions in this study.
Sponsors:   Children's Hospital Medical Center, Cincinnati;   Rare Diseases Clinical Research Network;   National Center for Advancing Translational Science (NCATS);   National Institute of Neurological Disorders and Stroke (NINDS);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified July 2015

Noninvasive Assessment of Neuromuscular Disease Using Electrical Impedance Myography

Condition:   Amyotrophic Lateral Sclerosis (ALS)
Intervention:   Device: EIM Measurements
Sponsors:   Skulpt, Inc.;   National Institutes of Health (NIH);   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified July 2015

Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis

Conditions:   Cryptococcal Meningitis;   Fungal Meningitis
Intervention:   Drug: Sertraline
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Infectious Disease Institute, Kampala, Uganda;   National Institute of Neurological Disorders and Stroke (NINDS);   Mbarara University of Science and Technology;   Ifakara Health Institute
Recruiting - verified July 2015

Transcranial Magnetic Stimulation for Focal Hand Dystonia

Condition:   Dystonia
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified July 2015

Treatment of Functional Movement Disorders With Psychotherapy

Condition:   Movement Disorders
Interventions:   Other: Group Psychotherapy;   Other: Cognitive behavior therapy based on self help
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified July 2015

Effects of Intensive Robot-assisted Therapy in Patients With Subacute Stroke

Condition:   Stroke
Interventions:   Device: RT;   Behavioral: Conventional rehabilitation (CR)
Sponsor:   Chang Gung Memorial Hospital
Completed - verified July 2015

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa (Dabigatran etexilate mesilate)
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified July 2015

Extended Venous Thromboembolism Prophylaxis Comparing Rivaroxaban to Aspirin Following Total Hip and Knee Arthroplasty

Condition:   Venous Thromboembolism
Intervention:   Drug: rivaroxaban and ASA
Sponsors:   David Anderson;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified July 2015

A Study to Assess Cardiovascular Outcomes Following Treatment With MK-3102 in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: MK-3102;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified July 2015

An Evaluation of Clinical Pharmacist-led Intervention on Clinical Outcomes in Patients With Ischemic Stroke

Condition:   Stroke
Interventions:   Other: Intervention (CPCRS) Group;   Other: Placebo
Sponsor:   Kaiser Permanente
Active, not recruiting - verified July 2015

Safety and Feasibility Study of Umbilical Cord Blood Mononuclear Cells Transplant to Treat Ischemic Stroke

Conditions:   Stroke;   Ischemic Stroke;   Brain Ischemia
Interventions:   Biological: UCBMC;   Procedure: surgery
Sponsors:   China Spinal Cord Injury Network;   Chinese University of Hong Kong;   The University of Hong Kong;   Prince of Wales Hospital, Shatin, Hong Kong;   Queen Mary Hospital, Hong Kong;   StemCyte, Inc.
Recruiting - verified July 2015

Phase II Front-line Ponatinib in Adult Philadelphia+/BCR-ABL+ Acute Lymphoblastic Leukemia.

Conditions:   Philadelphia Positive;   BCR-ABL Positive;   Acute Lymphoblastic Leukemia
Intervention:   Drug: Ponatinib
Sponsor:   Gruppo Italiano Malattie EMatologiche dell'Adulto
Recruiting - verified July 2015

Dual Antiplatelet Therapy Versus Oral Anticoagulation for a Short Time to Prevent Cerebral Embolism After TAVI

Conditions:   Aortic Valve Stenosis;   Stroke
Intervention:   Drug: aspirin+clopidogrel (Duoplavin)
Sponsor:   Andres Iñiguez Romo, MD, PhD
Recruiting - verified July 2015

AAV2-GDNF for Advanced Parkinson s Disease

Condition:   Parkinson's Disease
Intervention:   Genetic: Convection enhanced delivery/AAV2-GDNF
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified January 2015

PG2 Injection 500 mg in Acute Stroke Study (Pass)

Condition:   Acute Stroke
Interventions:   Drug: PG2;   Drug: placebo
Sponsors:   China Medical University Hospital;   National Taiwan University Hospital;   Shin Kong Wu Ho-Su Memorial Hospital;   Tri-Service General Hospital;   Changhua Christian Hospital;   National Cheng-Kung University Hospital;   Kaohsiung Medical University;   En Chu Kong Hospital;   Kuang Tien General Hospital;   Chung Shan Medical University;   Taipei Veterans General Hospital, Taiwan;   Kaohsiung Veterans General Hospital.;   Taipei Medical University Shuang Ho Hospital;   Cheng Hsin Rehabilitation Medical Center;   Taipei Medical University WanFang Hospital
Active, not recruiting - verified July 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Xarelto [SPAF] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban(Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified July 2015

Xarelto [SPAF-QOL] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban (Xarelto_ BAY59-7939)
Sponsor:   Bayer
Recruiting - verified July 2015

Efficacy of BNG-1 to Treat Acute Ischemic Stroke

Condition:   Ischemic Stroke
Interventions:   Drug: BNG-1;   Drug: Aspirin
Sponsor:   Chang Gung Memorial Hospital
Completed - verified July 2015

Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives

Conditions:   Stroke;   Transient Ischemic Attack;   Hypertension
Intervention:   Drug: all approved antihypertensive drugs; all approved statins
Sponsors:   Istituto Auxologico Italiano;   European Society of Hypertension;   Chinese Hypertension League
Recruiting - verified July 2015

Stroke Study: Operative Strategies to Reduce Cerebral Embolic Events During Coronary Artery Bypass Surgery

Condition:   Stroke
Interventions:   Procedure: No aortic clamping;   Procedure: partial occluding clamp;   Procedure: single cross clamp;   Procedure: cross clamp and partial occluding clamp
Sponsors:   Emory University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2015

Effect of Intervention to Improve Stroke Recognition

Condition:   Stroke
Interventions:   Behavioral: Hip Hop Stroke educational program;   Behavioral: Nutrition Education program
Sponsors:   Columbia University;   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified July 2015

Thrombin Generation and Thrombus Degradation in Cerebral Venous Thrombosis : Clinical and Radiological Correlations

Condition:   Cerebral Venous Thrombosis
Intervention:  
Sponsor:   University Hospital, Rouen
Recruiting - verified July 2015

Prognosis in Neurological Intensive Care Unit Patients (proNICU Cohort)

Condition:   Neurological Diseases
Intervention:  
Sponsor:   Charite University, Berlin, Germany
Recruiting - verified July 2015

Impact of Adalimumab Therapy on Brachial Endothelial Function and Large Artery Stiffness in Patients With Rheumatoid Arthritis

Condition:   Rheumatoid Arthritis
Interventions:   Device: transthoracic echocardiographic;   Device: Doppler ultrasound.;   Biological: blood samples
Sponsor:   Assistance Publique Hopitaux De Marseille
Completed - verified September 2014

Mood and Insulin Resistance in Adolescents At-Risk for Diabetes

Conditions:   Depression;   Impaired Glucose Tolerance
Interventions:   Other: The Blues Program;   Other: Hey Durham
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Institutes of Health Clinical Center (CC)
Active, not recruiting - verified March 2015

Hyper-CVAD and Ponatinib in Ph-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL)

Condition:   Leukemia
Interventions:   Drug: Cyclophosphamide;   Drug: Mesna;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Dexamethasone;   Drug: Ponatinib;   Drug: G-CSF  (Filgrastim);   Drug: Rituximab;   Drug: Methotrexate;   Drug: Cytarabine;   Drug: Solu-medrol ( Methyl Prednisolone);   Drug: Citrovorum (Leucovorin);   Drug: Prednisone;   Drug: Pegfilgrastim (Neulasta)
Sponsors:   M.D. Anderson Cancer Center;   Ariad Pharmaceuticals
Recruiting - verified July 2015

Longitudinal Studies of Brain Structure and Function in MPS Disorders

Conditions:   Mucopolysaccharidosis Type I;   Mucopolysaccharidosis Type II;   Mucopolysaccharidosis Type VI;   Mucopolysaccharidosis Type IV;   Mucopolysaccharidosis Type VII
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Rare Diseases Clinical Research Network;   National Center for Advancing Translational Science (NCATS);   National Institute of Neurological Disorders and Stroke (NINDS);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified July 2015

Sleep Apnea in Early to Mid-Stage Alzheimer's Disease

Conditions:   Early Onset Alzheimer Disease;   Alzheimer Disease;   Obstructive Sleep Apnea Syndromes
Interventions:   Device: CPAP Treatment;   Device: No treatment
Sponsors:   Centre Hospitalier Universitaire de Saint Etienne;   Association Lyonnaise de Logistique Posthospitalière
Recruiting - verified July 2015

Upper Arm Training With Armeo Spring for Stroke

Condition:   Stroke
Interventions:   Device: Sensing glove;   Device: Grip Sensor
Sponsor:   Spaulding Rehabilitation Hospital
Active, not recruiting - verified July 2015

REGISTRY EVALUATION OF VITAL INFORMATION FOR VADs IN AMBULATORY LIFE

Condition:   Congestive Heart Failure
Intervention:   Other: No Intervention
Sponsors:   University of Michigan;   National Heart, Lung, and Blood Institute (NHLBI);   Brigham and Women's Hospital
Recruiting - verified July 2015

A 30 Day Study to Evaluate Efficacy and Safety of Pre-hospital vs. In-hospital Initiation of Ticagrelor Therapy in STEMI Patients Planned for Percutaneous Coronary Intervention (PCI)

Conditions:   Myocardial Infarction;   Segment Elevation Myocardial Infarction (STEMI)
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsor:   AstraZeneca
Completed - verified July 2015

Muscle Atrophy, Physical Performance and Glucose Tolerance Post Stroke

Condition:   Stroke
Intervention:   Other: No intervention
Sponsor:   Baltimore VA Medical Center
Recruiting - verified July 2015

Minimally Invasive Surgical Treatment Versus Medical Management for Stroke Patients With Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Procedure: Minimally Invasive Surgery;   Other: Medical therapy
Sponsor:   University of Florida
Completed - verified July 2015

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Conditions:   Atherosclerosis;   Hypercholesterolemia
Interventions:   Drug: Statin Drugs;   Other: HMG-CoA Reductase Inhibitors
Sponsor:   National Institutes of Health Clinical Center (CC)
Active, not recruiting - verified April 2015

Statin/Vitamin D & Migraine Study

Condition:   Migraine
Interventions:   Drug: Simvastatin;   Dietary Supplement: Vitamin D;   Other: Placebo
Sponsor:   Rami Burstein
Active, not recruiting - verified July 2015

OSCAR - An Internet-based Supportive Coaching for Informal Caregivers of Adult Individuals With an Acquired Brain Injury

Conditions:   Caregivers;   Brain Injury
Interventions:   Behavioral: Internet-based supportive coaching OSCAR;   Other: Waiting-list control group (TAU)
Sponsors:   University of Bern;   Swiss National Science Foundation;   University Hospital Inselspital, Berne
Terminated - verified July 2015

Prediction of Stroke-associated Pneumonia

Condition:   Ischemic Stroke
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Siemens Health Care
Completed - verified June 2013

Genotype-Phenotype Correlations of Late Infantile Neuronal Ceroid Lipofuscinosis

Conditions:   Batten Disease;   Late Infantile Neuronal Lipofuscinosis
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   Rare Diseases Clinical Research Network;   National Center for Advancing Translational Science (NCATS);   National Institute of Neurological Disorders and Stroke (NINDS);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified July 2015

Role of Vitamin D in Secondary Prevention of Cardiovascular Events

Condition:   Cardiovascular Disease
Interventions:   Drug: Cholecalciferol;   Drug: Placebo
Sponsor:   Creighton University
Completed - verified July 2015

The Effects of Exenatide (Byetta ) on Energy Expenditure and Weight Loss in Nondiabetic Obese Subjects

Conditions:   Weight Loss;   Obesity
Interventions:   Drug: Byetta (exenatide);   Behavioral: Weight loss;   Other: Metabolic Chamber;   Drug: Placebo
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified December 2014

Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke

Condition:   Stroke
Interventions:   Behavioral: Treadmill walking;   Other: Magnetic resonance spectroscopy
Sponsors:   Department of Veterans Affairs;   Medical University of South Carolina
Completed - verified July 2015

Ferumoxytol and Gadolinium Magnetic Resonance Imaging (MRI) at 3 Tesla (T) and 7 Tesla (T) in Patients With Malignant Brain Tumors

Condition:   Brain Neoplasms
Intervention:   Drug: Ferumoxytol
Sponsors:   OHSU Knight Cancer Institute;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified July 2015

The Efficacy and Safety of MK0724 IV for Improvement of Neurological Damage and Recovery From Middle Cerebral Artery Ischemic Stroke (0724-018)

Condition:   Middle Cerebral Artery Stroke
Interventions:   Drug: Comparator: Placebo;   Drug: Comparator: MK0724
Sponsor:   Merck Sharp & Dohme Corp.
Terminated - verified July 2015

Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study (0954-133)

Condition:   Hypertension and Left Ventricular Hypertrophy (Thickening of the Main Pumping Chamber of the Heart)
Interventions:   Drug: MK0954,   /Duration of Treatment : 5 Years;   Drug: Comparator : atenolol /Duration of Treatment : 5 Years
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

A Study to Evaluate the Safety of an Investigational Drug (Etoricoxib) in Patients With Osteoarthritis (OA) or Rheumatoid Arthritis (RA)(0663-066)

Condition:   Rheumatoid Arthritis,Osteoarthritis
Interventions:   Drug: MK0663, etoricoxib;   Drug: Comparator: Diclofenac sodium
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

BRAIN (Biomarker Rapid Assessment of Ischemic iNjury)

Conditions:   Stroke;   Stroke Mimic(Conditions Presenting With Stroke-like Conditions)
Intervention:  
Sponsor:   Biosite
Completed - verified July 2015

Enhancing the Secondary Prevention of Coronary Artery Disease

Conditions:   Coronary Disease;   Ischemic Heart Disease
Intervention:   Behavioral: Evidence summaries endorsed by local opinion leaders
Sponsors:   University of Alberta;   Heart and Stroke Foundation of Canada;   Alberta Heritage Foundation for Medical Research;   Pfizer
Completed - verified July 2015

Get CardioSmart

You're Invited