Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

The Investigation of Public Awareness of Core Stroke Symptoms

Conditions:   Stroke;   Awareness;   Health Knowledge, Attitudes, Practice;   Core Symptoms;   FAST
Intervention:  
Sponsor:   Peking Union Medical College Hospital
Recruiting - verified May 2017

Evaluation of a Video-ludic Re-education of the Paretic Upper Limb in Chronic Hemipartic Patients Post Cerebral Vascular Accident

Conditions:   Stroke;   Motor Activity
Intervention:   Other: Rehabilitation
Sponsors:   Centre d'Investigation Clinique et Technologique 805;   Fondation Garches
Not yet recruiting - verified May 2017

Serum BDNF Role as a Biomarker for Stroke Rehabilitation

Conditions:   Stroke;   Biomarker;   Rehabilitation;   BDNF
Intervention:   Procedure: Conventional inpatient rehabilitation
Sponsor:   Samsung Medical Center
Recruiting - verified May 2017

Perfusion and Collaterals Imaging With C-arm CT

Condition:   Ischemic Stroke
Intervention:   Procedure: Percutaneous treatment of ischemic stroke
Sponsors:   University Health Network, Toronto;   Philips Healthcare
Recruiting - verified May 2017

Improving Functional Outcomes and Neuroplasticity by Using Ekso

Condition:   Stroke
Intervention:   Device: EKso training
Sponsor:   IRCCS Centro Neurolesi "Bonino-Pulejo"
Recruiting - verified May 2017

BP-TARGET : Blood Pressure Target in Acute Stroke to Reduce hemorrhaGe After Endovascular Therapy

Conditions:   Acute Stroke;   Blood Pressure;   Cerebral Hemorrhage
Interventions:   Other: Systolic blood pressure target < 130 mm Hg;   Other: Systolic blood pressure target < 185 mm Hg
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Not yet recruiting - verified May 2017

Prehospital Advanced Diagnostics and Treatment of Acute Stroke

Conditions:   Ischemic (Brain) Stroke;   Hemorrhagic Stroke;   TIA, Brain
Intervention:   Other: Prehospital diagnosis and treatment
Sponsors:   Norwegian Air Ambulance Foundation;   Ostfold Hospital Trust;   University of Oslo;   Oslo University Hospital
Recruiting - verified May 2017

Schlaganfallkonsortium Rhein-Neckar (Stroke Consortium Rhine-Neckar)

Conditions:   Ischemic Stroke;   Vascular Diseases;   Cardiovascular Diseases
Intervention:   Other: not applicable (observational study)
Sponsors:   University Hospital Heidelberg;   Dietmar Hopp Stiftung
Not yet recruiting - verified May 2017

Stroke Patients' Outpatient Rehabilitation Therapy (SPORT)

Conditions:   Stroke;   Incentives;   Stroke Rehabilitation
Interventions:   Behavioral: Transportation incentives;   Behavioral: Transportation and rehabilitation services incentives
Sponsors:   National University, Singapore;   Ministry of Health, Singapore;   Duke-NUS Medical School;   Changi General Hospital;   Singapore General Hospital
Not yet recruiting - verified May 2017

Proprioceptive Stimulation With Manual Bilateral Rhythmic Exercise in Post-stroke Patients

Conditions:   Stroke;   Hemiparesis
Interventions:   Other: Proprioceptive based training (PBT);   Other: Conventional neuromotor treatment (CNT).
Sponsor:   IRCCS San Camillo, Venezia, Italy
Recruiting - verified May 2017

Vessel Wall Imaging for Diagnosis and Monitoring of Central Nervous System (CNS) Vasculitis

Conditions:   Vasculitis, CNS;   Vasculitis, Cerebral
Intervention:   Device: MRI, including intracranial vessel wall imaging
Sponsor:   Mayo Clinic
Recruiting - verified May 2017

Prismatic Adaptation for Rehabilitation of Postural Imbalance After Stroke

Condition:   Chronic Right Supratensorial Stroke Patients
Interventions:   Device: The prismatic adaptation (PA);   Device: The sham prismatic adaptation (S-PA)
Sponsor:   Hospices Civils de Lyon
Not yet recruiting - verified May 2017

The Safety and Effectiveness of Transcatheter Aortic Valve Raplacemet in Intermediate Risk Patients With Bicuspid Aortic Stenosis

Condition:   Aortic Valve Disease
Interventions:   Procedure: TAVR;   Procedure: SAVR
Sponsor:   China National Center for Cardiovascular Diseases
Not yet recruiting - verified May 2017

Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy

Conditions:   Hypothermia;   Stroke, Acute
Interventions:   Drug: selective brain cooling by cold saline perfusion;   Device: mechanical thrombectomy
Sponsor:   Capital Medical University
Not yet recruiting - verified May 2017

Right Ventricular Function at Rest in Highlanders/Lowlanders

Condition:   High Altitude Pulmonary Hypertension
Intervention:  
Sponsors:   University of Zurich;   National Center of Cardiology and Internal Medicine, Kyrgyzstan
Recruiting - verified May 2017

Rehabilitation of Visual Function After Brain Injury

Conditions:   Stroke, Ischemic;   Brain Injuries;   Stroke Hemorrhagic;   Traumatic Brain Injury
Intervention:   Device: Neuro Vision Technology
Sponsors:   University Hospital, Gentofte, Copenhagen;   The Institute for the Blind and Partially Sighted (IBOS);   Copenhagen University Hospital at Herlev
Not yet recruiting - verified May 2017

The Antidepressant Effects of rTMS After Ischemic Stroke

Condition:   Post-stroke Depression
Interventions:   Device: active rTMS treatment;   Device: sham rTMS treatment
Sponsor:   Zhujiang Hospital
Not yet recruiting - verified January 2017

Volumetric Integral Phase-shift Spectroscopy for Noninvasive Detection of Hemispheric Bioimpedance Asymmetry in Acute Brain Pathology

Conditions:   Stroke;   Stroke, Acute;   Ischemic Stroke;   Hemorrhage;   Clot (Blood); Brain;   Subarachnoid Hemorrhage;   Cerebral Infarction;   Cerebral Hemorrhage;   Cerebral Stroke;   Intracerebral Hemorrhage;   Intracerebral Injury
Intervention:   Diagnostic Test: VIPS Monitoring
Sponsor:   Cerebrotech Medical Systems, Inc.
Recruiting - verified May 2017

Multiple Burrhole Therapy With Erythropoietin for Unstable Moyamoya

Conditions:   Ischemic Attack;   Ischemic Stroke;   Moyamoya Disease;   Burr Hole;   Angiogenesis
Intervention:   Drug: erythropoietin
Sponsor:   Ajou University School of Medicine
Completed - verified May 2017

A Research in Pharmacogenomics and Accurate Medication of Novel Oral Anticoagulants

Conditions:   Novel Oral Anticoagulants;   NOACs;   Rivaroxaban;   Apixaban;   Dabigatran;   Pharmacokinetics;   Pharmacodynamics;   Pharmacogenomics;   Accurate Medication
Intervention:   Genetic: detection of genotype
Sponsor:   Cui Yimin
Not yet recruiting - verified May 2017

Pivotal Study of VNS During Rehab After Stroke (VNS-REHAB)

Conditions:   Cerebrovascular Stroke;   Upper Extremity Paresis
Interventions:   Device: Paired Vagus Nerve Stimulation;   Other: Rehabilitation
Sponsors:   MicroTransponder Inc.;   ResearchPoint Global
Not yet recruiting - verified April 2017

Facilitation of Brain Plasticity for Language Recovery in Patients With Aphasia Due to Stroke

Conditions:   Stroke;   Aphasia
Interventions:   Device: experimental: tDCS;   Device: sham tDCS
Sponsor:   Nachum Soroker, MD
Not yet recruiting - verified May 2017

Fatigue Induced by Overground Wheelchair Propulsion in Persons With a Spinal Cord Injury: Upper Limb Saving or Straining?

Conditions:   Spinal Cord Injuries;   Fatigue; Muscle, Heart
Intervention:   Behavioral: Fatigue protocol
Sponsors:   Swiss Paraplegic Research;   Human Engineering Research Laboratories;   University Ghent
Recruiting - verified May 2017

Acute Myocardial Infarction and Acute Cerebral Infarction (AMIAC) Registry and Follow-up

Conditions:   Myocardial Infarction;   Cerebral Infarction;   Chronic Kidney Diseases;   Mortality
Intervention:  
Sponsor:   Guangdong General Hospital
Active, not recruiting - verified May 2017

Use of Direct Oral Anticoagulants in UK

Condition:   Stroke
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Dabigatran;   Drug: Apixaban
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Active, not recruiting - verified May 2017

Left Atrial Appendage Occlusion Versus New Oral Anticoagulants for Stroke Prevention in Patients With Non-valvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Device: left atrial appendage occlusion;   Drug: New oral anticoagulants
Sponsors:   Sejong General Hospital;   Korea University Anam Hospital;   Yonsei University;   Gachon University Gil Medical Center;   Ulsan University Hospital
Recruiting - verified May 2017

Constraint-induced Movement Therapy to Improve Gait and Mobility of People With Chronic Stroke

Conditions:   Rehabilitation;   Recovery of Function;   Stroke;   Lower Extremity Paresis
Intervention:   Behavioral: Lower extremity Constraint-induced movement therapy(LE-CIMT)
Sponsor:   University of Alabama at Birmingham
Not yet recruiting - verified February 2017

Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

Condition:   Multiple Sclerosis
Interventions:   Drug: Pioglitazone;   Drug: Montelukast;   Drug: Losartan;   Drug: Hydroxychloroquine
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified April 6, 2017

Patient Management During Major Abdominal Surgery: an Oxygen Consumption Protocol Compared to Standard Approach

Condition:   Hemodynamic Instability
Intervention:   Other: Oxygen consumption optimization
Sponsors:   Policlinico Universitario Agostino Gemelli;   Flavia Torrini;   Alessandra Bisanti;   Eleonora Filipponi;   Domenica Luca Grieco;   Massimo Antonelli
Not yet recruiting - verified May 2017

A Diabetes Improvement in Medical Therapy Versus SADJB Study

Conditions:   Diabetes Mellitus, Type 2;   Overweight
Interventions:   Procedure: SADJB-SG group;   Procedure: IMT group
Sponsor:   Universiti Putra Malaysia
Recruiting - verified May 2017

TACO Crossover TRIAL

Conditions:   Transfusion-associated Circulatory Overload;   Blood Transfusion Reaction
Interventions:   Procedure: Autologous RBC transfusion;   Procedure: Saline transfusion
Sponsor:   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Not yet recruiting - verified May 2017

Feasibility and Acceptability of Orthotic Shorts for People With Multiple Sclerosis

Condition:   Multiple Sclerosis
Interventions:   Device: Orthotic shorts;   Device: Placebo shorts
Sponsors:   Sheffield Hallam University;   Sheffield Teaching Hospitals NHS Foundation Trust
Not yet recruiting - verified May 2017

Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease?

Condition:   Parkinson Disease
Interventions:   Dietary Supplement: N-Acetylcysteine;   Procedure: Lumbar Puncture;   Radiation: Fluoroscopy
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 8, 2017

Concomitant Surgical Atrial Fibrillation Ablation in Double Valve Replacement

Conditions:   Atrial Fibrillation;   Valvular Heart Disease
Interventions:   Procedure: double valve replacement;   Procedure: surgical ablation
Sponsor:   Guangzhou General Hospital of Guangzhou Military Command
Recruiting - verified May 2017

Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Intermediate Risk of Mortality

Condition:   Aortic Valve Stenosis
Interventions:   Device: Transcatheter aortic valve implantation;   Procedure: Surgical aortic valve replacement
Sponsors:   Universitätsklinikum Hamburg-Eppendorf;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)
Recruiting - verified May 2017

Computer Simulated Atrial Fibrillation Tool

Condition:   Atrial Fibrillation
Intervention:   Other: Virtual Platform
Sponsors:   Nova Scotia Health Authority;   Cardiac Arrhythmia Network of Canada
Not yet recruiting - verified May 2017

Cerebral Reorganization of Stroke Patients After Repetitive Transcranial Magnetic Stimulation by Neuroimaging Analysis

Condition:   Stroke
Interventions:   Device: real Repetitive Transcranial Magnetic Stimulation;   Device: sham Repetitive Transcranial Magnetic Stimulation
Sponsors:   Peking Union Medical College Hospital;   Chinese Academy of Sciences;   University of Pennsylvania
Recruiting - verified December 2016

Cerebral Haemodynamic Changes During Cognitive Testing: A fTCD Study

Conditions:   Mild Cognitive Impairment;   Alzheimer Disease;   Vascular Dementia;   Healthy Controls
Interventions:   Other: Transcranial doppler ultrasonography;   Other: Blood pressure monitoring;   Other: Heart rate monitoring;   Other: End tidal CO2 monitoring;   Other: Addenbrooke's cognitive examination
Sponsor:   University of Leicester
Recruiting - verified March 2017

Electrical Impedance Tomography of Epilepsy

Condition:   Epilepsy
Intervention:   Device: Electrical Impedance Tomography
Sponsors:   University College, London;   University College London Hospitals
Not yet recruiting - verified May 2017

Outcomes in UK ACS Patients Prescribed Ticagrelor

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Completed - verified May 2017

High-resolution MRI of Inflammation in the Intracranial Arterial Vessel Wall

Condition:   Stroke
Intervention:   Drug: Ferumoxytol Injectable Product
Sponsors:   University of Utah;   AMAG Pharmaceuticals, Inc.
Enrolling by invitation - verified May 2017

Vascular Effects of Alirocumab in Acute MI-Patients

Conditions:   Coronary Vessel;   Coronary Circulation;   Atheroma; Myocardial
Interventions:   Drug: Alirocumab 150 MG/ML;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   Regeneron Pharmaceuticals
Recruiting - verified May 2017

Treatment Development of Triheptanoin (G1D)

Conditions:   Epilepsy;   GLUT1DS1;   Glut1 Deficiency Syndrome 1, Autosomal Recessive;   Glucose Metabolism Disorders;   Glucose Transport Defect;   Glucose Transporter Type 1 Deficiency Syndrome;   Glucose Transporter Protein Type 1 Deficiency Syndrome
Intervention:   Drug: Triheptanoin
Sponsors:   University of Texas Southwestern Medical Center;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2017

Prevention of Ischemic Conditions in Non-disabling Stroke/Transient Ischemic Attack With Remote Ischemic Conditioning

Conditions:   Transient Ischemic Attack;   Non-disabling Stroke
Intervention:   Device: Remote Ischemic Conditioning
Sponsor:   Capital Medical University
Not yet recruiting - verified May 2017

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

Condition:   Mitral Valve Failure
Interventions:   Device: Edwards SAPIEN 3 transcatheter heart valve;   Device: ASHI INTECC Astato XS 20
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified May 11, 2017

The PARTNER 3 - AVIV Trial

Conditions:   Aortic Stenosis;   Cardiomyopathy, Hypertrophic
Intervention:   Device: Edwards SAPIEN 3 transcatheter valve, Model 9600TFX
Sponsor:   Edwards Lifesciences
Recruiting - verified April 2017

CV Wizard: Does a Clinical Decision Support Tool Improve CVD Risk Factor Control in Safety Net Clinics?

Conditions:   Heart Attack;   Stroke;   Cardiovascular Diseases
Intervention:   Behavioral: CV WIZARD
Sponsors:   Kaiser Permanente;   Ochin, Inc.;   HealthPartners Institute
Not yet recruiting - verified May 2017

Evaluation of Coronary Artery Plaque Volume Progression/Regression and Safety of Alirocumab in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia

Conditions:   Hypercholesterolemia;   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553;   Drug: atorvastatin;   Drug: rosuvastatin;   Drug: fenofibrate;   Drug: bezafibrate;   Drug: ezetimibe;   Drug: antiplatelets;   Drug: anticoagulants
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified May 2017

Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly

Conditions:   Cognitive Decline;   Stroke
Intervention:  
Sponsor:   University Hospital, Lille
Recruiting - verified May 2017

Reproducibility Study of Transcranial Doppler

Condition:   Stroke
Intervention:   Diagnostic Test: Transcranial Doppler Ultrasound
Sponsor:   University of Edinburgh
Recruiting - verified May 2017

Clinical Trial of Mild Hypoxia Preconditioning in Patients Undergoing Interventional Treatment

Conditions:   Cerebrovascular Disease;   Mild Hypoxia Preconditioning;   Ischemia, Brain;   Brain Injury, Acute
Interventions:   Procedure: Mild Hypoxia Preconditioning;   Procedure: Sham preconditioning
Sponsor:   Hua Yan
Recruiting - verified May 2017

Head Position on Cerebral Haemodynamics in Acute Ischemic Stroke and Controls

Condition:   Ischemic Stroke
Intervention:   Other: change of head position
Sponsor:   University of Leicester
Completed - verified May 2016

Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI)

Condition:   Mitral Valve Regurgitation
Intervention:   Procedure: Mitral valve repair
Sponsors:   Odense University Hospital;   Danish Heart Foundation;   University of Southern Denmark
Recruiting - verified May 2017

Predictors of Occult Atrial Fibrillation in 171 Patients With Cryptogenic TIA and Minor Stroke

Condition:   Cryptogenic Transient Ischemic Attack and Minor Stroke
Intervention:   Procedure: Holter 21 days
Sponsor:   Versailles Hospital
Completed - verified May 2017

Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment

Condition:   Stroke
Interventions:   Device: Anodal or Cathodal tDCS;   Device: Sham;   Behavioral: Computerized naming therapy
Sponsors:   Johns Hopkins University;   National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - verified May 2017

Mental Practice Combined With Physical Practice Training for Gait Improvement in Parkinson's Disease Patients

Condition:   Parkinson Disease
Interventions:   Behavioral: Experimental training;   Behavioral: Control training
Sponsor:   University of Sao Paulo General Hospital
Recruiting - verified September 2016

A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT)

Condition:   Thromboembolism
Interventions:   Drug: Dabigatran etexilate;   Drug: Warfarin
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2017

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D)

Condition:   Anaemia
Interventions:   Drug: Daprodustat;   Drug: rhEPO;   Drug: Placebo;   Drug: Iron therapy
Sponsor:   GlaxoSmithKline
Recruiting - verified May 2017

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Non-Dialysis (ASCEND-ND)

Condition:   Anaemia
Interventions:   Drug: Daprodustat;   Drug: Darbepoetin alfa;   Drug: Placebo;   Drug: Iron Therapy
Sponsor:   GlaxoSmithKline
Recruiting - verified May 2017

Comparative Efficacy Study of Action Observation Therapy and Mirror Therapy After Stroke

Condition:   Stroke
Interventions:   Behavioral: Action observation therapy;   Behavioral: Mirror therapy;   Behavioral: Customary bilateral UE training
Sponsor:   Chang Gung Memorial Hospital
Recruiting - verified February 2017

Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®)

Condition:   Multiple Sclerosis
Interventions:   Drug: Ponesimod;   Other: Placebo
Sponsor:   Actelion
Recruiting - verified May 2017

Efficacy and Safety Trial With S 44819 After Recent Ischemic Cerebral Event

Condition:   Post Stroke Recovery
Interventions:   Drug: S 44819 150 mg twice a day;   Drug: S 44819 300 mg twice a day;   Drug: Placebo
Sponsors:   Institut de Recherches Internationales Servier;   ADIR Association
Recruiting - verified May 2017

Promoting Recovery Optimization With WALKing Exercise After Stroke

Condition:   Stroke
Interventions:   Behavioral: FAST;   Behavioral: FAST+SAM;   Behavioral: SAM
Sponsors:   University of Delaware;   University of Pennsylvania;   Christiana Care Health Services
Recruiting - verified May 2017

Dysphagia Evaluation After Stroke- Incidence and Effect of Oral Screen Intervention on Swallowing Dysfunction

Conditions:   Dysphagia;   Stroke
Intervention:   Device: Oral screen
Sponsors:   Umeå University;   University Hospital, Umeå
Not yet recruiting - verified June 2016

Prevention of Stroke by Left Atrial Appendage Closure in Atrial Fibrillation Patients After Intracerebral Hemorrhage

Conditions:   Atrial Fibrillation;   Stroke;   Intracerebral Hemorrhage
Interventions:   Device: LAAO;   Drug: Medical Therapy
Sponsors:   Karolinska University Hospital;   St. Jude Medical
Recruiting - verified May 2017

REstart or STop Antithrombotic Randomised Trial in France

Condition:   Cerebral Hemorrhage
Intervention:   Drug: Clopidogrel or Aspirin and/or Dypyridamole
Sponsors:   University Hospital, Lille;   Région Hauts de France, France;   Ministry of Health, France
Recruiting - verified May 2017

Can rTMS Enhance Somatosensory Recovery After Stroke?

Condition:   Stroke
Intervention:   Other: repetitive transcranial magnetic stimulation (rTMS)
Sponsor:   VA Office of Research and Development
Recruiting - verified May 2017

Reactive Oxygen Species Following Aortic Valve Replacement

Condition:   Aortic Stenosis
Intervention:  
Sponsor:   University Hospital Southampton NHS Foundation Trust
Recruiting - verified May 2017

Treatment Convenience in Patients Treated With Dabigatran for Stroke Prophylaxis in Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2017

Integrated Primary Care for Diabetes and Cardiovascular Disease

Conditions:   Diabetes Mellitus;   Hypertension;   Heart Failure;   Ischemic Heart Disease;   Cerebrovascular Disease
Interventions:   Behavioral: Outreach education training;   Behavioral: No outreach education training
Sponsors:   University of Sao Paulo General Hospital;   University of Sao Paulo;   Santa Catarina Federal University;   University of Cape Town;   Federal University of Bahia;   Medical Research Council, South Africa;   University of East Anglia
Recruiting - verified January 2017

Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques

Condition:   Multiple Sclerosis
Interventions:   Drug: Methylprednisolone;   Drug: Methylprednisolone
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified February 16, 2017

Abdominal Massage for Bowel Dysfunction

Condition:   Multiple Sclerosis
Interventions:   Behavioral: Abdominal massage;   Behavioral: Optimised bowel care
Sponsor:   Glasgow Caledonian University
Completed - verified May 2017

FoodFLIP: Testing the Effectiveness of a Food Information App to Promote the Selection of Healthier Foods

Conditions:   Consumer Behavior;   Diet, Food, and Nutrition
Intervention:   Other: Nutrition Rating Systems
Sponsors:   University of Toronto;   Heart and Stroke Foundation of Canada;   Dietitians of Canada
Not yet recruiting - verified May 2017

Quality and Safety of Initial Management for ST-segment Elevation Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Other: Daily practice care for patients with suspected of STEMI
Sponsors:   Centre Hospitalier de la Région d'Annecy;   University Hospital, Grenoble
Recruiting - verified May 2017

Patient Convenience Study- NIS RELATE

Condition:   Atrial Fibrillation
Interventions:   Drug: Pradaxa (dabigatran);   Drug: Vitamin K antagonist
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2017

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified May 2017

Protocol-guided Rapid Evaluation of Veterans Experiencing New Transient Neurological Symptoms

Conditions:   Transient Ischemic Attack;   Stroke
Intervention:   Other: Quality Improvement Program
Sponsor:   VA Office of Research and Development
Recruiting - verified May 2017

Pre-Diabetes Cardiovascular Care (Pre-Diabetes Wizard)

Condition:   Pre-diabetes
Intervention:   Other: Clinical Decision Support
Sponsors:   HealthPartners Institute;   Essentia Health
Enrolling by invitation - verified May 2017

Detection of Atrial Fibrillation After Cardiac Surgery

Conditions:   Atrial Fibrillation;   Atrial Flutter;   C.Surgical Procedure; Cardiac;   Arrhythmias, Cardiac
Interventions:   Device: Medtronic SEEQ™ mobile cardiac telemetry system;   Other: Usual Care
Sponsor:   St. Michael's Hospital, Toronto
Recruiting - verified May 2017

Measurement of the Cerebral Saturation for Assessment of Safety of Epidural Anaesthesia During Abdominal Surgery

Conditions:   Surgical Complications From General Anesthesia;   Cerebral Ischemia;   Anesthesia; Reaction
Intervention:  
Sponsor:   Jagiellonian University
Completed - verified May 2017

Contrast Enhanced SWI for Carotid Plaque Imaging

Condition:   Carotid Plaque Imaging
Intervention:   Other: Methods of carotid wall imaging
Sponsor:   Hyun Seok Choi, M.D.
Recruiting - verified May 2017

Mobile Service Robot for Task-Oriented Stroke Therapy: User Evaluations

Condition:   Stroke
Intervention:   Device: Mobile Service Robot
Sponsor:   University of Pennsylvania
Completed - verified May 2017

Evaluation of Plasma Non-coding RNAs as Biomarkers in Coronary Heart Disease

Condition:   Coronary Disease
Intervention:   Other: No intervention
Sponsor:   Tongji Hospital
Enrolling by invitation - verified May 2017

Virtual Occupational Therapy Application

Conditions:   Stroke;   Hemiparesis
Intervention:   Behavioral: VOTA Therapy
Sponsors:   Barron Associates, Inc.;   University of Virginia
Completed - verified January 2017

Brainstem Grey Matter and Cerebral Autoregulation in Migraine With Aura.

Condition:   Migraine With Aura
Interventions:   Other: Magnetic resonance imaging;   Other: Transcranial Doppler
Sponsor:   University Hospital, Toulouse
Completed - verified May 2017

A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Recruiting - verified May 2017

Cholinergic Receptor Imaging in Dystonia

Conditions:   Cervical Dystonia;   Dystonia;   Movement Disorder;   Focal Dystonia
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 5, 2017

The Relationship Between Clotting Factor VIII and Bleeding Adverse Reactions in Patients Under the Therapies of Thrombolysis, Anticoagulation and Anti-platelet

Conditions:   Bleeding;   Ischemic Stroke
Intervention:  
Sponsors:   Zhujiang Hospital;   Guangdong Province, Department of Science and Technology
Recruiting - verified July 2016

Which Parameters of Short-term Blood Pressure Variability Best Predict Early Outcomes in Acute Ischemic Stroke

Condition:   Stroke
Intervention:  
Sponsor:   Dongguan People's Hospital
Completed - verified May 2017

Translating Intensive Arm Rehabilitation in Stroke to a Telerehabilitation Format

Conditions:   Stroke;   Hemiparesis
Interventions:   Device: Home-Based BATRAC plus TTT;   Device: Lab-based BATRAC plus TTT;   Behavioral: Delayed Entry Usual Care
Sponsor:   VA Office of Research and Development
Recruiting - verified May 2017

The Influence of day-to Day BPV on Long-term Adverse Outcomes in Patients Ischemic Stroke

Condition:   Stroke
Intervention:  
Sponsor:   Zhu Shi
Completed - verified May 2017

Renoprotective Effects of Dapagliflozin in Type 2 Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Diabetic Nephropathies
Interventions:   Drug: Dapagliflozin 10mg QD;   Drug: Gliclazide 30mg QD
Sponsors:   M.H.H. Kramer;   AstraZeneca
Recruiting - verified May 2017

Peripheral Nerve Stimulation and Motor Training in Stroke

Condition:   Stroke
Intervention:   Procedure: PNS
Sponsors:   University of Sao Paulo General Hospital;   Fundação Faculdade de Medicina;   National Institute of Neurological Disorders and Stroke (NINDS);   The Cleveland Clinic
Recruiting - verified October 2016

A Study of the ReCor Medical Paradise System in Clinical Hypertension

Conditions:   Hypertension;   Vascular Diseases
Interventions:   Device: The Paradise® Renal Denervation Ultrasound System;   Device: Sham Procedure
Sponsor:   ReCor Medical, Inc.
Recruiting - verified May 2017

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified May 2017

A Study to Compare Tivozanib Hydrochloride to Sorafenib in Subjects With Refractory Advanced RCC

Condition:   Carcinoma, Renal Cell
Interventions:   Drug: tivozanib hydrochloride;   Drug: Sorafenib
Sponsor:   AVEO Pharmaceuticals, Inc.
Recruiting - verified May 2017

Natural History of Rett Syndrome & Related Disorders

Conditions:   Rett Syndrome;   MECP2 Duplication dIsorder;   RTT-related Conditions
Intervention:  
Sponsors:   University of Alabama at Birmingham;   National Institutes of Health (NIH);   National Center for Advancing Translational Science (NCATS);   Rare Diseases Clinical Research Network;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2017

A Cross-sectional Study for the Determination of the Prevalence of Non-valvular Atrial Fibrillation Among Patients Diagnosed With Hypertension

Conditions:   Hypertension;   Atrial Fibrillation
Intervention:   Other: Standard of care
Sponsor:   Bayer
Completed - verified May 2017

Investigation of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty

Conditions:   Blood Loss;   Anatomic Total Shoulder Arthroplasty;   Reverse Total Shoulder Arthroplasty;   Transfusion;   Tranexamic Acid
Interventions:   Drug: Tranexamic Acid;   Drug: Placebo
Sponsor:   Rush University Medical Center
Completed - verified April 2016

Special Drug Use Investigation of Xarelto for Venous Thromboembolism (VTE)

Condition:   Venous Thromboembolism
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified May 2017

Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes

Condition:   Transcatheter Aortic Valve Replacement
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Acetylsalicylic acid;   Drug: Clopidogrel
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified May 2017

ERic Acute StrokE Recanalization (ERASER)

Condition:   Ischemic Stroke
Intervention:   Device: ERIC® and SOFIA™
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Active, not recruiting - verified May 2017

Propensity to Develop Plasticity in the Parieto- and Cerebello-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing

Conditions:   Writer's Cramp;   Healthly Volunteers;   Cervical Dystonia
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 11, 2017

Evaluating Use of Microwave Technology to Differentiate Hemorrhagic Stroke From Infarction in the Acute Phase

Condition:   Stroke
Intervention:   Device: Strokefinder MD100 measurement
Sponsors:   Mikael Elam;   Medfield Diagnostics;   Chalmers University of Technology
Recruiting - verified May 2017

Validation of Nicom Device to Measure Stoke Volume Variation

Condition:   Anesthesia
Interventions:   Procedure: Volume loading;   Drug: Ringer solution
Sponsor:   Hopital Foch
Recruiting - verified May 2017

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Active, not recruiting - verified May 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified May 2017

Improving Motor Stroke Recovery Using Patient-tailored Non-invasive Brain Stimulation

Condition:   Stroke
Interventions:   Device: Sham TDCS;   Device: Anodal TDCS;   Device: Cathodal TDCS;   Device: Magnetic Resonance Imaging (MRI)
Sponsor:   Sunnybrook Health Sciences Centre
Not yet recruiting - verified May 2017

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Completed - verified May 2017

Checking a Security Protocol of Modified FUT and Efficacy Reducing the Constriction the Movement Time in 12 Hours

Condition:   Stroke
Interventions:   Device: Tubular mesh.;   Other: Classical kinesiotherapy.
Sponsor:   University of Sao Paulo
Recruiting - verified August 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified May 2017

Midodrine for Ischemic Stroke With Penumbra

Condition:   Stroke
Intervention:   Drug: Midodrine
Sponsor:   University of Utah
Withdrawn - verified May 2017

Robotic Therapy and Transcranial Direct Current Stimulation in Patients With Stroke

Condition:   Stroke
Interventions:   Device: Robotic Therapy;   Device: Active tDCS;   Device: Sham tDCS;   Other: Physical Therapy;   Other: Occupational Therapy
Sponsors:   University of Sao Paulo General Hospital;   Conselho Nacional de Desenvolvimento Científico e Tecnológico
Terminated - verified December 2015

A Comparison Between the Exoskeleton Hybrid Assistive Limb and Conventional Gait Training Early After Stroke

Conditions:   Stroke;   Gait, Hemiplegic;   Ambulation Difficulty;   Hemiparesis
Interventions:   Device: Hybrid Assistive Limb (HAL); gait training;   Other: Control Group; Conventional gait training
Sponsors:   Danderyd Hospital;   University of Tsukuba
Completed - verified May 2017

A Prospective Study of Medical Therapy Against Cryoballoon Ablation in Symptomatic Recent Onset Persistent AF

Condition:   Atrial Fibrillation
Interventions:   Device: single ablation (CryoBalloonAblation (CBA);   Drug: sequential drug adjustment (propafenone, sotalol or flecainide)
Sponsor:   University Hospital, Ghent
Recruiting - verified May 2017

Effects of Home-based vs. Clinic-based Rehabilitation on Sensorimotor, Cognition, Daily Function, and Participation

Condition:   Chronic Stroke
Intervention:   Behavioral: bilateral training with and without mirror feedback
Sponsor:   Chang Gung Memorial Hospital
Completed - verified November 2016

Getting Older Adults OUT-of -Doors

Condition:   Older Adults With Decreased Outdoor Walking Ability
Interventions:   Other: GO-OUT program;   Other: Task-oriented outdoor walking workshop
Sponsors:   University of Manitoba;   University of Toronto;   McGill University;   University of Alberta
Completed - verified May 2016

Hemiplegic Shoulder Pain and Rotator Cuff Injuries

Conditions:   Shoulder Pain;   Stroke;   Rotator Cuff Injuries
Interventions:   Drug: Hyaluronic Acid;   Drug: Physiological saline solution;   Other: physical therapy and occupational therapy
Sponsor:   Chang Gung Memorial Hospital
Recruiting - verified August 2016

Comparison of Electrophysiologic and Ultrasound Guidance for Onabotulinum Toxin A Injections in Focal Upper Extremity Dystonia and Spasticity

Conditions:   Dystonia;   Focal Dystonia;   Musician's Dystonia;   Muscle Spasticity
Interventions:   Procedure: BoNT injection;   Procedure: US guidance;   Procedure: E-stim Guidance
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 17, 2017

Tranexamic Acid Mechanisms and Pharmacokinetics in Traumatic Injury

Conditions:   Hemorrhage;   Shock;   Wounds and Injuries
Interventions:   Drug: Tranexamic Acid;   Other: Placebo
Sponsors:   Washington University School of Medicine;   United States Department of Defense
Recruiting - verified May 2017

Bivalirudin vs Heparin in NSTEMI and STEMI in Patients on Modern Antiplatelet Therapy in SWEDEHEART

Conditions:   ST-segment Elevation Myocardial Infarction;   Non ST-segment Elevation Myocardial Infarction
Interventions:   Drug: bivalirudin;   Drug: Heparin
Sponsors:   Uppsala University;   Lund University
Completed - verified May 2017

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified May 2017

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability

Conditions:   Chronic Troublesome Sialorrhea;   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Intellectual Disability
Interventions:   Drug: IncobotulinumtoxinA;   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified May 2017

Optimizing Health Outcomes in Patients With Symptomatic Aortic Valve Disease

Condition:   Aortic Valve Disease
Intervention:  
Sponsors:   Duke University;   Patient-Centered Outcomes Research Institute;   American College of Cardiology;   The Society of Thoracic Surgeons
Enrolling by invitation - verified May 2017

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified May 2017

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2017

My Stroke Team (MYST): Stroke App Pilot Study

Conditions:   Stroke;   Comorbidity;   Chronic Disease
Intervention:   Other: Strengthening Community-Based Stroke Care: A Pilot Study of a Community Navigation and Rehabilitation Intervention that Includes a Mobile Health Solution
Sponsor:   McMaster University
Recruiting - verified May 2017

Left-Atrium-Appendage Occluder Register - GErmany

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Stiftung Institut fuer Herzinfarktforschung
Active, not recruiting - verified May 2017

Critical Periods After Stroke Study (CPASS)

Conditions:   Stroke;   Brain Infarction;   Brain Ischemia;   Cerebral Infarction;   Cerebrovascular Disorders
Interventions:   Behavioral: Early Intensive upper extremity motor training;   Behavioral: Sub-acute intensive upper extremity motor training;   Behavioral: Chronic intensive upper extremity motor training;   Behavioral: Control
Sponsors:   MedStar National Rehabilitation Network;   Georgetown University;   University of Wisconsin, Madison;   The Catholic University of America;   Medstar Health Research Institute
Recruiting - verified May 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified May 2017

Sampling P2Y12 Receptor Inhibition With Prasugrel and Ticagrelor in Patients Submitted to Thrombolysis

Conditions:   Acute Coronary Syndrome;   Platelet Function
Interventions:   Drug: Prasugrel;   Drug: Ticagrelor
Sponsor:   Federal University of São Paulo
Completed - verified May 2017

HEart and BRain Interfaces in Acute Ischemic Stroke

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Center for Stroke Research Berlin
Active, not recruiting - verified May 2017

Controlled Education Of Patients After Stroke

Conditions:   Stroke;   Hypertension
Intervention:   Other: optimised follow-up
Sponsors:   University Hospital, Lille;   Ministry of Health, France
Recruiting - verified May 2017

Interactive Motor Imagery in Virtual Reality

Conditions:   Spinal Cord Injury;   Stroke
Intervention:   Device: iCTuS-L
Sponsor:   University of Zurich
Recruiting - verified May 2017

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   Cleveland Clinic Coordinating Center for Clinical Research (C5R);   Quintiles, Inc.
Active, not recruiting - verified May 2017

fMRI Neurofeedback for Motor Rehabilitation

Conditions:   Stroke;   fMRI
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified October 11, 2016

Kinect-based Upper Limb Rehabilitation System in Stroke Patients

Conditions:   Stroke;   Hemiplegia;   Virtual Rehabilitation
Interventions:   Procedure: Kinect-based rehabilitation plus occupational therapy;   Other: sham virtual rehabilitation education plus occupational therapy
Sponsors:   Seoul National University Bundang Hospital;   Microsoft Research;   The Ministry of Science, ICT and Future Planning, Korea
Suspended - verified May 2017

CNS and Plasma Amyloid-Beta Kinetics in Alzheimer's Disease

Condition:   Alzheimer's Disease
Intervention:  
Sponsors:   Washington University School of Medicine;   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified May 2017

Clinical Effect Size of an Educational Intervention in the Home and Compliance on People Who Suffer From Stroke

Condition:   Stroke
Interventions:   Behavioral: Educational intervention;   Device: Smartphone-based application
Sponsor:   University of Malaga
Recruiting - verified March 2017

Efficacy of Unilateral Versus Bilateral Approach to Robot-Assisted Rehabilitation in Patients With Subacute Stroke

Condition:   Subacute Stroke
Interventions:   Device: InMotion3 (IMT);   Device: Bi-Manu-Track (BMT);   Behavioral: Control intervention (CI)
Sponsor:   Chang Gung Memorial Hospital
Withdrawn - verified June 2016

Physical Fitness Training in Subacute Stroke (PHYS-Stroke)

Condition:   Stroke
Interventions:   Procedure: physical fitness training;   Procedure: relaxation
Sponsor:   Charite University, Berlin, Germany
Active, not recruiting - verified December 2016

OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA

Conditions:   Coronary Heart Disease;   Diabetes;   Vascular Lesions;   Chronic Total Occlusion of Coronary Artery;   Restenosis
Intervention:   Device: TAXUS™ Element long stent
Sponsors:   Centre Chirurgical Marie Lannelongue;   Cochin Hospital;   Centre Hospitalier de La Rochelle;   University Hospital, Limoges;   Hôpital de la Timone;   Centre Hospitalier Universitaire de Nice;   Centre Hospitalier de PAU;   Rangueil Hospital;   Versailles Hospital
Active, not recruiting - verified May 2017

Reperfusion of Pulmonary Arteriovenous Malformations After Embolotherapy

Condition:   Pulmonary Arteriovenous Malformations
Intervention:   Procedure: Angiography and embolotherapy
Sponsor:   St. Michael's Hospital, Toronto
Recruiting - verified May 2017

Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III

Condition:   Intracerebral Hemorrhage
Intervention:   Drug: rt-PA
Sponsors:   Johns Hopkins University;   National Institute of Neurological Disorders and Stroke (NINDS);   Genentech, Inc.;   Emissary International LLC
Recruiting - verified May 2017

Intensive Motor Training After Perinatal Stroke to Enhance Walking

Condition:   Perinatal Stroke
Interventions:   Behavioral: Early leg training;   Behavioral: Delayed leg training;   Behavioral: Parent leg training
Sponsors:   University of Alberta;   Alberta Innovates Health Solutions
Recruiting - verified December 2016

Extramembranous and Interosseous Technique of Tibialis Posterior Tendon Transfer

Conditions:   Muscle Injury;   Nerve Injury;   Poliomyelitis;   Leprosy;   Cerebral Palsy
Interventions:   Procedure: Interosseous route of TPTT;   Procedure: Extra membranous route of TPTT
Sponsor:   Iva Hauptmannova
Recruiting - verified May 2017

Topical Anti-angiogenic Therapy for Telangiectasia in HHT: Proof of Concept

Condition:   Hereditary Hemorrhagic Telangiectasia
Interventions:   Drug: Topical timolol maleate;   Drug: placebo saline drops
Sponsors:   St. Michael's Hospital, Toronto;   University of California, San Francisco;   The Hospital for Sick Children;   University of Toronto;   Sunnybrook Health Sciences Centre;   Ryerson University;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2017

Maternal and Neurodevelopmental Outcomes of in Utero Antiepileptic Drug (AED) Exposure

Conditions:   Epilepsy;   Pregnancy
Intervention:  
Sponsors:   Emory University;   The EMMES Corporation;   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified May 2017

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2017

Deep Brain Stimulation Surgery for Movement Disorders

Conditions:   Parkinson's Disease;   Essential Tremor;   Dystonia
Intervention:   Procedure: Deep Brain Stimulation
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 9, 2017

Xarelto [SPAF] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban(Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Active, not recruiting - verified May 2017

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: bicalutamide;   Drug: buserelin;   Drug: flutamide;   Drug: goserelin acetate;   Drug: leuprolide acetate;   Drug: orteronel;   Drug: triptorelin
Sponsors:   Radiation Therapy Oncology Group;   National Cancer Institute (NCI);   NRG Oncology
Active, not recruiting - verified May 2017

Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke

Condition:   Stroke
Interventions:   Drug: Alteplase;   Drug: Placebo
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Recruiting - verified May 2017

Surgery as a Treatment for Medically Intractable Epilepsy

Conditions:   Epilepsy;   Epilepsy, Temporal Lobe;   Partial Epilepsy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 9, 2017

Study of Factors Influencing Post-stroke Dementia

Conditions:   Cerebrovascular Disorders;   Dementia
Intervention:  
Sponsors:   University Hospital, Lille;   Ministry of Health, France
Recruiting - verified May 2017

Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia

Condition:   Hereditary Hemorrhagic Telangiectasia
Intervention:  
Sponsors:   St. Michael's Hospital, Toronto;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2017

SMN Copy Number Distribution in Mali, West Africa

Condition:   Spinal Muscular Atrophy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified May 18, 2017

The Nordic Aortic Valve Intervention Trial

Condition:   Critical Aortic Stenosis
Interventions:   Procedure: Transcatheter Aortic Valve Implantation;   Procedure: Surgical Aortic Valve Replacement
Sponsors:   Rigshospitalet, Denmark;   Odense University Hospital;   Sahlgrenska University Hospital, Sweden;   Danish Heart Foundation;   Copenhagen Trial Unit, Center for Clinical Intervention Research
Active, not recruiting - verified May 2017

Genotype-Phenotype Correlations of Late Infantile Neuronal Ceroid Lipofuscinosis

Conditions:   Batten Disease;   Late Infantile Neuronal Ceroid Lipofuscinosis
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   Rare Diseases Clinical Research Network;   National Institute of Neurological Disorders and Stroke (NINDS);   National Institutes of Health (NIH)
Recruiting - verified May 2017

Recording and Modulation of Neuronal Mechanisms During Operant Conditioning: a MEG Study

Condition:   Central Nervous System
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Suspended - verified May 18, 2017

International Active Surveillance Study - Safety of Contraceptives: Role of Estrogens

Condition:   Contraception
Intervention:  
Sponsors:   Center for Epidemiology and Health Research, Germany;   Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma
Active, not recruiting - verified May 2017

Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer

Conditions:   Pain/Cancer;   Pain, Intractable
Interventions:   Drug: (Resiniferatoxin)(RTX);   Drug: Intrathecal Resiniferatoxin
Sponsors:   National Institute of Dental and Craniofacial Research (NIDCR);   National Institute of Neurological Disorders and Stroke (NINDS);   Sorrento Therapeutics, Inc.
Suspended - verified May 9, 2017

Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System

Conditions:   Central Nervous System Disease;   Multiple Sclerosis
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 9, 2017

Catheter Ablation vs. Standard Conventional Treatment in Patients With LV Dysfunction and AF

Conditions:   Atrial Fibrillation;   Heart Failure
Interventions:   Procedure: Radiofrequency ablation;   Other: Conventional treatment
Sponsor:   Biotronik SE & Co. KG
Completed - verified May 2017

Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome

Condition:   Antiphospholipid Syndrome
Intervention:  
Sponsor:   Duke University
Recruiting - verified May 2017

Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo

Condition:   Epilepsies, Partial
Interventions:   Drug: Lyrica (pregabalin);   Drug: placebo
Sponsor:   Pfizer
Recruiting - verified May 2017

Reference Values for Plasma Catechols

Conditions:   Healthy Volunteers;   Normal Physiology
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 10, 2017

Natural History of Stroke: Cause and Development

Conditions:   Nervous System Disease;   Transient Ischemic Attack;   Neurologic Disorders;   Stroke;   Vascular Disease
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 9, 2017

Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)

Condition:   Multiple Sclerosis
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 16, 2017