Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Evaluating Use of Microwave Technology to Differentiate Hemorrhagic Stroke From Infarction Before Arrival to Hospital

Condition:   Stroke
Interventions:   Device: Strokefinder MD100 prehospital measurement;   Device: Strokefinder MD100 hospital measurement
Sponsors:   Mikael Elam;   Medfield Diagnostics;   Chalmers University of Technology
Not yet recruiting - verified July 2015

Stroke Imaging Package Study

Conditions:   Atherosclerosis;   Stroke;   Infarction, Middle Cerebral Artery;   Vertebrobasilar Insufficiency;   Cerebral Small-vessel Disease;   Moyamoya Syndrome
Intervention:  
Sponsors:   Wei-Hai Xu;   Peking University First Hospital;   Peking Union Medical College Hospital;   General Hospital of Chinese Armed Police Forces;   Daping Hospital and the Research Institute of Surgery of the Third Military Medical University;   General Hospital of Shenyang Military Region;   Subei People's Hospital of Jiangsu Province;   Second Affiliated Hospital, School of Medicine, Zhejiang University;   Beijing Jishuitan Hospital;   Beijing Friendship Hospital;   Fuxing Hospital of Capital Medical University;   Fujian Medical University;   Jingan District Central Hospital of Shanghai (Jingan Branch of Huashan Hospital Affiliated to Fudan University);   First Hospital of Jilin University;   The First Affiliated Hospital of University of South China;   Qilu Hospital of Shandong University (Qingdao);   Tangshan Gongren Hospital;   Wuhan University;   Third Affiliated Hospital, Sun Yat-Sen University;   Renmin Hospital of Wuhan University;   Qilu Hospital;   Qingdao Municipal Hospital
Not yet recruiting - verified June 2015

Validation of Nicom Device to Measure Stoke Volume Variation

Condition:   Anesthesia
Interventions:   Procedure: Volume loading;   Drug: Ringer solution
Sponsor:   Hopital Foch
Recruiting - verified June 2015

A New Rehabilitation Treatment Following Stroke

Condition:   Unisensory vs. Multisensory Stimulation Delivered During the Acute vs. Chronic Phase Following Stroke
Intervention:   Behavioral: A New Rehabilitation Treatment following Stroke
Sponsor:   University of Oxford
Recruiting - verified June 2015

PreventIon of IMT Progression in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage-IMT Study

Conditions:   Brain Ischemia;   Intracranial Hemorrhages
Interventions:   Drug: cilostazol;   Drug: Probucol;   Drug: Aspirin;   Drug: placebo of cilostazol;   Drug: Placebo of aspirin;   Device: Intima-medial thickness
Sponsors:   Asan Medical Center;   Korea Otsuka Pharmaceutical Co.,Ltd.
Active, not recruiting - verified June 2015

Ankle Robot to Reduce Foot-drop in Stroke

Conditions:   Stroke;   Foot-drop
Interventions:   Device: Treadmill plus anklebot;   Behavioral: Treadmill only
Sponsor:   Department of Veterans Affairs
Not yet recruiting - verified June 2015

Self-regulated Constraint-induced Movement Therapy in Subacute Stroke Patients

Condition:   Stroke
Interventions:   Other: Self-regulated constraint-induced movement therapy;   Other: Constraint-induced movement therapy;   Other: Conventional occupational therapy
Sponsors:   University of Western Sydney;   The Hong Kong Polytechnic University
Completed - verified June 2015

Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis

Conditions:   End Stage Renal Failure on Dialysis;   Body Fluid Retention;   Impedance;   Cardiac Output, Low
Interventions:   Device: CardioScreen 1000 - Haemodynamic Measurement System, Medis;   Device: BCM- Body Composition Monitor, Fresenius Medical Care;   Device: SCHILLER, BR-102 plus, Ambulatory Blood Pressure Monitoring System
Sponsor:   Medical University of Warsaw
Recruiting - verified June 2015

Assessment and Quantification of Collateral by ASL MRI

Condition:   Stroke
Intervention:  
Sponsors:   Chinese PLA General Hospital;   Beijing Tiantan Hospital
Recruiting - verified June 2015

Effect of Rosuvastatin on Prognosis of Clinical Response in Acute Ischemic Stroke Patients(REPAIRS)

Condition:   Infarction, Anterior Cerebral Artery
Intervention:   Drug: Rosuvastatin
Sponsors:   Second Affiliated Hospital of Soochow University;   Taicang No.1 People’s hospital;   AstraZeneca;   National Natural Science Foundation of China
Not yet recruiting - verified June 2015

Early Sleeve Gastrectomy In New Onset Diabetic Obese Patients

Condition:   Type 2 Diabetes Mellitus
Interventions:   Procedure: Laparoscopic Sleeve Gastrectomy plus conventional medical therapy;   Drug: Conventional medical therapy
Sponsors:   Azienda Ospedaliera Santa Maria, Terni, Italy;   Ethicon Endo-Surgery
Not yet recruiting - verified June 2015

Lacunar Intervention Trial 1 (LACI-1)

Conditions:   Cerebral Small Vessel Diseases;   Cognitive Impairment;   Stroke
Interventions:   Drug: isosorbide mononitrate;   Drug: cilostazol
Sponsors:   University of Edinburgh;   University of Nottingham
Not yet recruiting - verified June 2015

A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care

Conditions:   Pain;   Chronic Pain;   Mental Disorders;   Cardiovascular Diseases;   Diabetes Mellitus, Type 2;   Arthritis
Interventions:   Other: Unblinded to Genetic Testing Results;   Other: Blinded to Genetic Testing Results
Sponsor:   Proove Bioscience, Inc.
Recruiting - verified June 2015

Risk of Intracranial Hemorrhage in Users of Oral Antithrombotic Drugs

Conditions:   Intracranial Hemorrhages;   Stroke
Intervention:   Drug: antithrombotic drugs
Sponsors:   St. Olavs Hospital;   Norwegian University of Science and Technology
Active, not recruiting - verified June 2015

The Risk of Major Bleeding With Novel Anti-platelets: A Comparison of Ticagrelor With Clopidogrel in a Real World Population of 5000 Patients Treated for Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Bleeding;   Novel Anti-platelets;   Ticagrelor;   Clopidogrel
Intervention:   Drug: Ticagrelor
Sponsors:   Aintree University Hospitals NHS Foundation Trust;   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Royal Liverpool and Broadgreen University Hospitals NHS Trust;   Countess of Chester NHS Foundation Trust;   St Helens & Knowsley Teaching Hospitals NHS Trust
Recruiting - verified June 2015

App-delivered Therapy for Arabic Readers With Hemianopic Alexia

Condition:   Stroke
Intervention:   Behavioral: Reading Training
Sponsor:   University College London Hospitals
Not yet recruiting - verified June 2015

Evaluation of Transcutaneous Trigeminal Nerve Stimulation for Prevention of Cerebral Vasospasm After Subarachnoid Haemorrhage

Condition:   Subarachnoid Haemorrhage (SAH)
Intervention:   Device: Transcutaneous Electrical Nerve Stimulation (TENS)
Sponsor:   Poitiers University Hospital
Not yet recruiting - verified June 2015

Assessment of the GORE® EXCLUDER® Conformable AAA Endoprosthesis in the Treatment of Abdominal Aortic Aneurysms- High Neck Angulation Substudy

Condition:   Aortic Aneurysm, Abdominal
Intervention:   Device: GORE® EXCLUDER® Conformable AAA Endoprosthesis
Sponsor:   W.L.Gore & Associates
Not yet recruiting - verified June 2015

Assessment of the GORE® EXCLUDER® Conformable AAA Endoprosthesis in the Treatment of Abdominal Aortic Aneurysms- Short Neck Substudy

Condition:   Aortic Aneurysm, Abdominal
Intervention:   Device: GORE® EXCLUDER® Conformable AAA Endoprosthesis
Sponsor:   W.L.Gore & Associates
Not yet recruiting - verified June 2015

Acupuncture for Ischemic Post-stroke Depression

Condition:   Post-stroke Depression
Interventions:   Device: acupuncture;   Drug: placebo;   Device: sham-acupoint acupuncture;   Drug: Fluoxetine
Sponsors:   Menghan Li;   State Administration of Traditional Chinese Medicine of the People's Republic of China
Not yet recruiting - verified June 2015

Family-based Approach to Promotion of Health Project 2

Conditions:   Lifestyle Intervention;   Atherosclerosis;   Cardiovascular Risk Factor
Interventions:   Behavioral: Intensive Individual Intervention Program;   Behavioral: Peer-To-Peer Program Intervention
Sponsors:   Icahn School of Medicine at Mount Sinai;   American Heart Association
Not yet recruiting - verified June 2015

Perioperative Goal Directed Hemodynamic Therapy Based on Noninvasive Monitoring in Patients With Hip Fracture

Condition:   Hip Fractures
Interventions:   Other: PGDT based on noninvasive monitoring;   Device: System ClearSight® and Platform EV Clinic 1000®
Sponsor:   Althaia Xarxa Assistencial Universitària de Manresa
Recruiting - verified June 2015

A Predictive Score for the Ischemic Etiology of a Transient Visual Disturbances (VASCO)

Condition:   Vision Disorders
Intervention:   Other: Clinical, ophthalmological and neurological evaluation
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified June 2015

Nephrologist Follow-up Versus Usual Care After Acute Kidney Injury

Conditions:   Acute Kidney Injury;   Chronic Kidney Disease
Intervention:   Behavioral: AKI Follow-up Clinic
Sponsors:   St. Michael's Hospital, Toronto;   Sunnybrook Health Sciences Centre;   University Health Network, Toronto;   Mount Sinai Hospital, Canada
Not yet recruiting - verified June 2015

Real Evidence of Anticoagulation Treatment in Non-valvular Atrial Fibrillation in Germany and the UK: REACT-AF2

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Bristol-Myers Squibb;   IMS Health;   Oxon Epidemiology
Active, not recruiting - verified June 2015

"Mobile Stroke Unit"-Concept for Delivery of Specialized Acute Stroke Care to Patients in Remote Areas

Condition:   Acute Stroke
Interventions:   Device: MSU-based stroke management;   Device: Control stroke management
Sponsor:   University Hospital, Saarland
Recruiting - verified July 2015

Low Frequency rTMS With Structured PT Training on Restoring Upper Extremity Function

Condition:   Stroke
Interventions:   Device: Low frequency rTMS;   Behavioral: structured physiotherapy upper limb training
Sponsors:   Queen Elizabeth Hospital, Hong Kong;   The Hong Kong Polytechnic University
Not yet recruiting - verified July 2015

Real-Life Evidence on Stroke Prevention in SPAF

Condition:   Atrial Fibrillation (Prevention of Stroke)
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Vitamin K antagonists
Sponsors:   Bayer;   Janssen, LP
Recruiting - verified June 2015

Vascular Responses to UV Exposure in Pregnancy

Condition:   Pregnancy
Interventions:   Radiation: UVA radiation;   Radiation: Sham Control
Sponsors:   University of Edinburgh;   NHS Lothian
Not yet recruiting - verified June 2015

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Not yet recruiting - verified June 2015

Unilateral vs. Bilateral Approaches to Hybrid Stroke Rehabilitation

Condition:   Stroke
Interventions:   Procedure: Unilateral Hybrid Intervention;   Procedure: Bilateral Hybrid Intervention;   Device: BMT robot;   Other: Training;   Procedure: Robot-Assisted Training
Sponsor:   Chang Gung Memorial Hospital
Enrolling by invitation - verified April 2015

Cognitive Behavioural Therapy for Menopausal Symptoms

Condition:   Menopausal Depression
Intervention:   Other: Cognitive Behavioural Therapy for Menopausal Symptoms
Sponsors:   St. Joseph's Healthcare Hamilton;   Ontario Mental Health Foundation
Not yet recruiting - verified June 2015

Study to Document the Effectiveness of Dysport in Patients Suffering From Upper Limb Spasticity (ULS) After Stroke

Condition:   Post Stroke Arm Spasticity
Intervention:  
Sponsor:   Ipsen
Recruiting - verified June 2015

Safety Study of the PulseRider® in Patients Undergoing Treatment for Bifurcation Intracranial Aneurysms

Condition:   Brain Aneurysm
Intervention:   Device: PulseRider
Sponsors:   Pulsar Vascular;   Medpace, Inc.
Recruiting - verified June 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified July 2015

Vascular Ultrasound Screening in Patients With Ischemic Cerebrovascular Disease: a Multi-center Registry Study

Condition:   Stroke
Intervention:  
Sponsors:   Xuanwu Hospital, Beijing;   The First Affiliated Hospital of Shanxi Medical University;   Liaocheng Brains Hospital;   Tianjin Huanhu Hospital;   Baotou City Central Hospital;   First Hospital of Jilin University;   First Affiliated Hospital of Harbin Medical University;   First Hospital of China Medical University;   LanZhou University;   First Affiliated Hospital of Xinjiang Medical University;   The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School;   The First Affiliated Hospital of Soochow University;   Anhui Provincial Hospital;   Guangdong Provincial Hospital of Traditional Chinese Medicine;   Zhuhai  People's Hospital;   Fujian Provincial Hospital;   Mianyang Central Hospital;   The Second Affiliated Hospital of Kunming Medical University;   Brains Hospital of Hunan Province;   Henan Provincial Hospital;   Luoyang Central Hospital Affiliated to Zhengzhou University;   National Health and Family Planning Commission Stroke Prevention Engineering Committee
Recruiting - verified July 2015

Evaluation the Effectiveness of the Risk Minimisation Activities in the Treatment of Stroke Prevention in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Study on the Use of Botulinum Toxin Type A in the Treatment of Chronic Post-stroke Spastic Patients

Condition:   Spasticity
Intervention:  
Sponsor:   Ipsen
Recruiting - verified June 2015

Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)

Conditions:   Vertigo;   Dizziness
Intervention:   Device: VRT Care
Sponsors:   David E. Newman-Toker, MD PhD;   National Institute on Deafness and Other Communication Disorders (NIDCD);   GN Otometrics
Not yet recruiting - verified June 2015

Robotic Therapy and Transcranial Direct Current Stimulation in Patients With Stroke

Condition:   Stroke
Interventions:   Device: Robotic Therapy;   Device: Active tDCS;   Device: Sham tDCS;   Other: Physical Therapy;   Other: Occupational Therapy
Sponsors:   University of Sao Paulo General Hospital;   Conselho Nacional de Desenvolvimento Científico e Tecnológico
Recruiting - verified June 2015

Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial

Conditions:   Coronary Artery Disease;   Coronary Disease;   Myocardial Ischemia;   Arteriosclerosis;   Cardiovascular Diseases
Interventions:   Procedure: Fractional flow reserve-guided CABG;   Procedure: Angiography-guided CABG
Sponsor:   Odense University Hospital
Recruiting - verified June 2015

Patient and Provider Assessment of Lipid Management Registry

Conditions:   Hyperlipidemia;   Hypercholesterolemia;   Cardiovascular Disease;   Diabetes;   Chronic Kidney Disease (CKD);   Hypertension;   Smoking;   Myocardial Infarction (MI);   Unstable Angina;   Angina;   Coronary Artery Disease (CAD);   Stroke;   Transient Ischemic Attack (TIA);   Carotid Stenosis;   Peripheral Arterial Disease;   Atherosclerosis;   Claudication
Intervention:  
Sponsors:   Duke University;   Regeneron Pharmaceuticals;   Sanofi
Recruiting - verified June 2015

Community Engagement for Early Recognition and Immediate Action in Stroke

Condition:   Ischemic Stroke
Intervention:   Behavioral: Community-based Stroke Awareness Program
Sponsors:   Northwestern University;   Patient Centered Outcome Research Institute
Recruiting - verified June 2015

Intra-arterial Autologous Bone-marrow Mononuclear Cells Infusion for Acute Ischemic Stroke

Condition:   Stroke
Interventions:   Drug: Autologous bone marrow mononuclear stem cells;   Other: No intervention
Sponsors:   Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud;   Iniciativa Andaluza en Terapias Avanzadas 
Recruiting - verified May 2015

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability

Conditions:   Chronic Troublesome Sialorrhea;   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Intellectual Disability
Interventions:   Drug: IncobotulinumtoxinA;   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified June 2015

Evaluation of SVV From NICOM as a Predictor of Fluid Responsiveness in Prone Position During Spine Surgery

Conditions:   Fluid Responsiveness;   Prone Position;   Non Invasive Cardiac Output Monitoring
Intervention:   Other: Fluid loading to evaluate fluid responsiveness
Sponsor:   Samsung Medical Center
Recruiting - verified June 2015

SMARTCap Stroke Study: A Field Deployable Blood Test for Stroke

Condition:   Stroke
Intervention:   Device: SMARTCap
Sponsor:   University Hospitals Coventry and Warwickshire NHS Trust
Recruiting - verified June 2015

Evaluation of 5 Days Holter and 30 Days Thumb-ECG for Detection of Atrial Fibrillation in Stroke Patients

Conditions:   Atrial Fibrillation;   Stroke
Intervention:   Device: Holter monitoring and Thumb ECG
Sponsor:   Herlev Hospital
Completed - verified June 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified June 2015

Decompressive Hemicraniectomy in Intracerebral Hemorrhage

Condition:   Cerebral Hemorrhage
Interventions:   Procedure: Decompressive craniectomy (DC) and best medical treatment;   Procedure: Best medical treatment
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified June 2015

Hispanic Secondary Stroke Prevention Initiative

Condition:   Stroke
Interventions:   Behavioral: Community Health Worker (CHW) home visits, coaching phone calls, group sessions .;   Other: usual care and health education brochures every 4 months.
Sponsors:   University of Miami;   National Institute on Minority Health and Health Disparities (NIMHD)
Recruiting - verified July 2015

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2015

The CREST-2 Registry

Condition:   Carotid Artery Diseases
Intervention:   Device: Carotid Artery Stent
Sponsors:   University of Maryland;   National Institute of Neurological Disorders and Stroke (NINDS);   Centers for Medicare and Medicaid Services;   Mayo Clinic;   Society for Vascular Surgery;   American College of Cardiology
Recruiting - verified June 2015

Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVR

Condition:   Peripheral Artery Disease (PAD)
Interventions:   Drug: Ticagrelor;   Drug: Comparator
Sponsors:   AstraZeneca;   CPC Clinical Research
Recruiting - verified June 2015

Active Surveillance Research Program for the Assessment of the Safety and the Effectiveness of Linagliptin

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve Replacement

Condition:   Aortic Stenosis
Interventions:   Device: Lotus Valve System;   Device: CoreValve Transcatheter Aortic Valve Replacement System
Sponsor:   Boston Scientific Corporation
Enrolling by invitation - verified July 2015

Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study

Conditions:   Abdominal Aortic Aneurysm;   Coronary Heart Disease;   Sudden Cardiac Death;   Intracerebral Haemorrhage;   Heart Failure;   Ischemic Stroke;   Myocardial Infarction;   Stroke;   Peripheral Arterial Disease;   Stable Angina Pectoris;   Subarachnoid Haemorrhage;   Transient Ischemic Attack;   Unstable Angina;   Cardiac Arrest
Intervention:  
Sponsors:   University College, London;   Wellcome Trust;   National Institute for Health Research, United Kingdom;   London School of Hygiene and Tropical Medicine
Active, not recruiting - verified July 2015

Efficacy and Security of an Endovascular Treatment as First Choice Procedure Compared With a Standard Intravenous Thrombolytic Therapy Treatment for Patients With Acute Ischemic Stroke Within 4.5 Hours After Onset

Condition:   Acute Ischaemic Stroke
Interventions:   Procedure: EVT (endovascular treatment );   Procedure: IVT (intravenous thrombolytic therapy)
Sponsor:   Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Completed - verified June 2015

Thoratec Corporation HeartMate III™ CE Mark Clinical Investigation Plan

Condition:   Advanced Refractory Left Ventricular Heart Failure
Intervention:   Device: Left Ventricular Assist System (LVAS)
Sponsors:   Thoratec Corporation;   Center for Life Sciences (C3TK);   Emergo Group;   Krakow Cardiovascular Research Institute
Active, not recruiting - verified June 2015

Trevo and Medical Management Versus Medical Management Alone in Wake Up and Late Presenting Strokes

Condition:   Ischemic Stroke
Interventions:   Device: Trevo Thrombectomy Procedure;   Other: Medical Management
Sponsor:   Stryker Neurovascular
Recruiting - verified June 2015

OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity

Conditions:   Muscle Spasticity;   Stroke
Interventions:   Biological: onabotulinumtoxinA;   Drug: placebo (normal saline)
Sponsor:   Allergan
Recruiting - verified July 2015

Sedation vs. Intubation for Endovascular Stroke TreAtment

Condition:   Acute Ischemic Stroke
Intervention:   Procedure: Endovascular recanalisation
Sponsor:   University Hospital Heidelberg
Recruiting - verified June 2015

Haemodynamic Effects of Apelin Agonists and Antagonists in Man in COPD With Raised Pulmonary Artery Pressures

Conditions:   COPD;   Pulmonary Hypertension
Interventions:   Procedure: Forearm plethysmography;   Procedure: Haemodynamic studies
Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   Wellcome Trust;   University of Cambridge
Completed - verified January 2015

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   The Cleveland Clinic
Recruiting - verified June 2015

Combined Bronchodilators in Chronic Obstructive Pulmonary Disease and the Risk of Adverse Cardio-pulmonary Events

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified July 2015

Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech

Conditions:   Apraxia of Speech;   Aphasia;   Cerebrovascular Accident
Interventions:   Behavioral: Normal Auditory Feedback;   Behavioral: Masked Auditory Feedback;   Behavioral: Altered Auditory Feedback
Sponsors:   University of North Carolina, Chapel Hill;   National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - verified June 2015

Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions

Conditions:   Chronic Troublesome Sialorrhea;   Parkinson's Disease;   Post-stroke;   Traumatic Brain Injury
Interventions:   Drug: IncobotulinumtoxinA (100 Units);   Drug: IncobotulinumtoxinA (75 Units);   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified June 2015

Sequential Expansion of Comparative Effectiveness of Anticoagulants

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Acute Stroke Advancing Program Using Telemedicine

Condition:   Stroke
Intervention:   Other: Telemedicine consultation system
Sponsors:   Xijing Hospital;   Department of Science and Technology of Shanxi Province;   Fourth Military Medical University
Recruiting - verified September 2014

Heart-Brain Retraining for Stroke Rehabilitation

Condition:   Stroke
Interventions:   Behavioral: Repetitive Task Practice (RTP);   Behavioral: Voluntary cycling + RTP;   Behavioral: Assisted cycling + RTP
Sponsor:   The Cleveland Clinic
Completed - verified June 2015

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)

Condition:   Brain Ischemia
Interventions:   Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
Sponsor:   Genentech, Inc.
Recruiting - verified July 2015

Elite Controller and ART-treated HIV+ Statin Versus ASA Treatment Intervention Study

Condition:   HIV Infection
Interventions:   Drug: Aspirin 81 mg daily;   Drug: Atorvastatin 40 mg daily
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified September 2014

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified June 2015

Examining the Spasmodic Dysphonia Diagnosis and Assessment Procedure (SD-DAP) for Measuring Symptom Change

Conditions:   Spasmodic Dysphonia;   Laryngeal Dystonia
Intervention:  
Sponsors:   Emory University;   National Institute of Neurological Disorders and Stroke (NINDS);   Office of Rare Diseases (ORD)
Not yet recruiting - verified June 2015

Trevo® Retriever Registry Post Market Surveillance

Condition:   Ischemic Stroke
Intervention:  
Sponsor:   Stryker Neurovascular
Recruiting - verified June 2015

The Safety and Effectiveness of Warfarin and Dabigatran Prescribed in the Non-Valvular Atrial Fibrillation Population With DoD Healthcare Coverage

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Completed - verified July 2015

CNS and Plasma Amyloid-Beta Kinetics in Alzheimer's Disease

Condition:   Alzheimer's Disease
Intervention:  
Sponsors:   Washington University School of Medicine;   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified June 2015

Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects

Condition:   Sialorrhea
Intervention:   Drug: MYOBLOC
Sponsor:   US WorldMeds LLC
Recruiting - verified June 2015

Prehospital Tranexamic Acid Use for Traumatic Brain Injury

Condition:   Traumatic Brain Injury
Interventions:   Drug: 1 gram Tranexamic Acid (TXA);   Drug: 2 grams TXA;   Drug: 0.9% Sodium Chloride injectable
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI);   U.S. Army Medical Research and Materiel Command;   Canadian Institutes of Health Research  (CIHR);   Heart and Stroke Foundation of Canada;   American Heart Association;   Defence Research and Development Canada
Recruiting - verified June 2015

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

GLORIA-AF Registry Program (Phase II/III)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Influenza Vaccine To Prevent Adverse Vascular Events: A Pilot Study

Condition:   Heart Failure
Intervention:   Drug: inactivated trivalent influenza vaccine
Sponsor:   McMaster University
Recruiting - verified July 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified June 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Acenocoumarol
Sponsor:   Bayer
Recruiting - verified June 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Phenprocoumon
Sponsor:   Bayer
Recruiting - verified June 2015

Compound Edaravone Injection for Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: Compound Edaravone Injection;   Drug: Edaravone Injection
Sponsor:   Jiangsu Simcere Pharmaceutical Co., Ltd.
Completed - verified July 2015

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

Condition:   Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Withdrawn - verified July 2015

The Medtronic CoreValve™ Evolut R™ CE Mark Clinical Study

Condition:   Aortic Stenosis
Intervention:   Device: The CoreValve™ Evolut R TAV™ system
Sponsors:   Medtronic Cardiovascular;   Medtronic
Active, not recruiting - verified June 2015

ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial

Condition:   End Stage Renal Failure on Dialysis
Interventions:   Drug: Spironolactone;   Drug: Placebo
Sponsors:   University Hospital, Brest;   Central Hospital, Nancy, France;   Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - verified June 2015

Arm Spasticity - Non-Interventional Study Early BIRD (BoNT Treatment: Initial and Repeated Documentation) [AS-NIS Early BIRD]

Condition:   Post-stroke Arm Spasticity
Intervention:  
Sponsor:   Ipsen
Recruiting - verified June 2015

Anticoagulant Utilization Pattern

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Transcranial Direct Current Stimulation for Improving Gait Training in Stroke

Conditions:   Stroke;   Cerebral Vascular Accident
Intervention:   Device: transcranial direct current stim
Sponsors:   University of Arkansas;   University of Central Arkansas
Recruiting - verified June 2015

Evaluation of the Effects of Rehabilitation Using the "Wii" on Upper Limb Kinematics in Chronic Stroke Patients.

Conditions:   Post-stroke Hemiparetic Patients (at Least 6 Months Post Stroke);   Age Between 18-75 Years
Interventions:   Behavioral: WII Rehabilitation;   Behavioral: Traditional rehabilitation
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified June 2015

A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: rivaroxaban 2.5 mg;   Drug: rivaroxaban 15 mg;   Drug: rivaroxaban 10 mg;   Drug: aspirin (ASA);   Drug: vitamin K antagonist (VKA);   Drug: clopidogrel;   Drug: prasugrel;   Drug: ticagrelor
Sponsors:   Janssen Scientific Affairs, LLC;   Bayer
Recruiting - verified June 2015

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified June 2015

The Efficacy of Intensive Nutritional Supplement in Patient With Stroke

Conditions:   Stroke;   Malnutrition
Intervention:   Dietary Supplement: high protein supplement
Sponsors:   Seoul National University Bundang Hospital;   Myongji Hospital
Terminated - verified July 2015

A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)

Condition:   Sickle Cell Disease
Interventions:   Drug: Prasugrel;   Drug: Placebo
Sponsors:   Eli Lilly and Company;   Daiichi Sankyo Inc.
Active, not recruiting - verified June 2015

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Active, not recruiting - verified June 2015

The Effect of Low Frequency STN DBS on Sleep and Vigilance in Parkinson's Disease (PD) Patients

Condition:   Parkinson's Disease
Interventions:   Other: DBS stimulator setting alteration;   Other: virtual reality simulator
Sponsors:   University of Alabama at Birmingham;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2015

Improving Arm and Hand Functions in Chronic Stroke (CIHR 2012-2015)

Conditions:   Stroke;   Upper Extremity Paresis
Interventions:   Behavioral: Music Supported Rehabilitation;   Behavioral: Conventional Upper Extremity Therapy
Sponsor:   Baycrest
Active, not recruiting - verified June 2015

Treatment of Post Stroke Fatigue With a Wakefulness Promoting Agent

Conditions:   Stroke;   Post Stroke Fatigue
Interventions:   Drug: modafinil;   Drug: placebo
Sponsor:   Herlev Hospital
Terminated - verified June 2015

A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities

Condition:   Cardiovascular Disease, Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: aleglitazar
Sponsor:   Hoffmann-La Roche
Completed - verified July 2015

VITAL-DEP: Depression Endpoint Prevention in the VITamin D and OmegA-3 TriaL

Conditions:   Depression;   Depressive Symptoms;   Mood
Interventions:   Dietary Supplement: vitamin D3;   Drug: omega-3 fatty acids (fish oil);   Dietary Supplement: Fish oil placebo;   Dietary Supplement: Vitamin D placebo
Sponsors:   Brigham and Women's Hospital;   National Institute of Mental Health (NIMH)
Active, not recruiting - verified July 2015

Danhong Injection in the Treatment of Acute Ischemic Stroke

Condition:   Acute Stroke
Interventions:   Drug: Danhong injection;   Procedure: Standard medical care;   Drug: placebo
Sponsors:   China  Academy of Chinese Medical Sciences;   China: State Food and Drug Administration
Recruiting - verified June 2015

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aortic Dissection.

Conditions:   Turner Syndrome;   Aortic Aneurysm;   Ischemic Heart Disease;   Hypertension;   Congenital Heart Defect
Intervention:  
Sponsor:   University of Aarhus
Recruiting - verified June 2015

RESCUE Stroke Caregiver Website to Enhance Discharge Planning

Conditions:   Depression;   Quality of Life;   Self Efficacy;   Recovery of Function;   Stress;   Positive Aspects of Caregiving
Interventions:   Behavioral: Caregiver problem-solving;   Other: Standard Care
Sponsor:   Department of Veterans Affairs
Recruiting - verified June 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified June 2015

Aspirin Withdrawal in Non-ischaemic Cardiomyopathy Study

Condition:   Heart Failure
Interventions:   Drug: Aspirin;   Other: withdrawal of aspirin
Sponsor:   The Alfred
Completed - verified June 2015

Post-Marketing Surveillance of Prazaxa® on the Long-term Use in Patients With Nonvalvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Prazaxa
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified July 2015

Study in Parkinson's Disease of Exercise

Condition:   Parkinson Disease
Interventions:   Behavioral: Moderate Exercise;   Behavioral: Vigorous Exercise
Sponsors:   University of Colorado, Denver;   University of Illinois at Chicago;   University of Pittsburgh;   Rush University Medical Center;   National Institute of Neurological Disorders and Stroke (NINDS);   Northwestern University
Recruiting - verified July 2015

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Longitudinal Study of Bone Disease in Children With Mucopolysaccharidoses (MPS) I, II, and VI

Condition:   Mucopolysaccharidoses
Intervention:  
Sponsors:   Los Angeles Biomedical Research Institute;   Rare Diseases Clinical Research Network;   National Institute of Neurological Disorders and Stroke (NINDS);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Children's Hospital & Research Center Oakland;   National Center for Advancing Translational Science (NCATS)
Recruiting - verified June 2015

Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection

Condition:   Esophageal Cancer
Intervention:   Other: fluid optimisation
Sponsor:   University Hospital, Linkoeping
Recruiting - verified June 2015

Mifepristone for Metabolic Syndrome

Conditions:   Endocrine Disease;   Diabetes
Intervention:   Drug: Mifepristone
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified March 2015

ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis

Conditions:   Tetraplegia;   Spinal Cord Injury;   Brachial Plexus Injury;   Muscular Dystrophy;   ALS;   Brainstem Stroke
Intervention:   Device: Implantation of ECoG sensors on the brain surface
Sponsor:   University of Pittsburgh
Completed - verified June 2015

Microelectrode Brain-Machine Interface for Individuals With Tetraplegia

Conditions:   Tetraplegia;   Spinal Cord Injury
Intervention:   Device: Implantation of NeuroPort Arrays in the motor cortex
Sponsors:   University of Pittsburgh;   Department of Defense;   Johns Hopkins University
Recruiting - verified June 2015

Dystonia Coalition Projects

Conditions:   Dystonia;   Voice Disorders
Intervention:  
Sponsors:   Hyder A. Jinnah, MD, PhD;   National Institute of Neurological Disorders and Stroke (NINDS);   Office of Rare Diseases (ORD);   Allergan;   Dystonia Study Group
Recruiting - verified June 2015

A Study of RoActemra/Actemra (Tocilizumab) in Comparison to Etanercept in Patients With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Condition:   Cardiovascular Disease, Rheumatoid Arthritis
Interventions:   Drug: etanercept;   Drug: tocilizumab [RoActemra/Actemra]
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified July 2015

MR WITNESS: A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients

Condition:   Acute Stroke
Intervention:   Drug: IV rt-PA
Sponsors:   Lee Schwamm;   National Institute of Neurological Disorders and Stroke (NINDS);   Genentech, Inc.
Recruiting - verified June 2015

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Conditions:   Atherosclerosis;   Hypercholesterolemia
Interventions:   Drug: Statin Drugs;   Other: HMG-CoA Reductase Inhibitors
Sponsor:   National Institutes of Health Clinical Center (CC)
Active, not recruiting - verified April 2015

Strategy for Adequate Blood Pressure Lowering in the Patients With Intracranial Atherosclerosis

Condition:   Brain Ischemia
Interventions:   Procedure: Aggressive BP lowering;   Procedure: modest blood pressure lowering
Sponsors:   Asan Medical Center;   Pfizer
Active, not recruiting - verified June 2015

TomVasc - Vascular Effects of Tomato Extract

Conditions:   Ischemic Heart Disease;   Transient Ischemic Attack;   Stroke;   Peripheral Vascular Disease
Interventions:   Dietary Supplement: Ateronon;   Dietary Supplement: Placebo
Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   Cambridge Theranostics Ltd
Completed - verified July 2012

Risk of Cardiovascular Events in Patients With Type 2 Diabetes Initiating Oral Antidiabetic Treatments

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsors:   Bristol-Myers Squibb;   AstraZeneca;   University of Pennsylvania
Active, not recruiting - verified June 2015

SMN Copy Number Distribution in Mali, West Africa

Condition:   Spinal Muscular Atrophy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified June 2015

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified July 2015

Neuroprotective Study of Electroacupuncture Pretreatment in Patients Undergoing Cardiac Surgery

Conditions:   Stroke;   Brain Injuries
Interventions:   Procedure: non electroacupuncture stimulation;   Procedure: Electroacupuncture pretreatment
Sponsors:   Xijing Hospital;   Fourth Military Medical University
Completed - verified November 2009

PreventIon of CArdiovascular Events in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage

Conditions:   Brain Ischemia;   Intracranial Hemorrhages
Interventions:   Drug: Cilostazol;   Drug: Probucol;   Drug: Aspirin;   Drug: placebo of cilostazol;   Drug: placebo of aspirin;   Device: ankle-brachial index (ABI);   Device: intima-medial thickness (IMT);   Device: new asymptomatic brain hemorrhage;   Device: new ischemic lesions on follow-up FLAIR images
Sponsors:   Asan Medical Center;   Korea Otsuka Pharmaceutical Co.,Ltd.
Active, not recruiting - verified June 2015

BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: D,L-lysine acetylsalicylate (Aspirin, BAY81-8781) 500 mg IV;   Drug: D,L-lysine acetylsalicylate (Aspirin, BAY81-8781) 250 mg IV;   Drug: Acetylsalicylic acid (Aspirin, BAYe4465) 300 mg Tablet
Sponsor:   Bayer
Completed - verified June 2015

Early Goal-directed Volume Resuscitation in Severe Acute Pancreatitis

Condition:   Acute Pancreatitis
Interventions:   Other: PiCCO-parameter-guided volume resuscitation;   Other: Control-group
Sponsor:   Technische Universität München
Recruiting - verified June 2015

Progesterone for the Treatment of Traumatic Brain Injury III

Condition:   Traumatic Brain Injury
Intervention:   Drug: Progesterone
Sponsors:   David Wright;   Medical University of South Carolina;   Neurological Emergencies Treatment Trials Network (NETT)
Terminated - verified June 2015

Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer

Conditions:   Pain/Cancer;   Pain, Intractable
Interventions:   Drug: (Resiniferatoxin)(RTX);   Drug: Intrathecal Resiniferatoxin
Sponsors:   National Institute of Dental and Craniofacial Research (NIDCR);   National Institute of Neurological Disorders and Stroke (NINDS);   Sorrento Therapeutics, Inc.
Suspended - verified May 2015

Sitagliptin Cardiovascular Outcome Study (MK-0431-082)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Sitagliptin phosphate;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Duke Clinical Research Institute, Oxford Diabetes Trials Unit
Completed - verified June 2015

A Study of All-Cause Mortality and Cardiovascular Morbidity in CKD Patients on Dialysis and Those Not on Renal Replacement Therapy Receiving Mircera or Reference ESAs.

Condition:   Anemia
Interventions:   Drug: ESAs (darbepoetin alfa, epoetin alfa or epoetin beta);   Drug: methoxy polyethylene glycol-epoetin beta [Mircera];   Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
Sponsor:   Hoffmann-La Roche
Recruiting - verified July 2015

A Clinical Trial of IntensiVE Dialysis

Conditions:   Renal Replacement Therapy;   Renal Dialysis;   End Stage Kidney Disease;   End Stage Renal Disease;   Uremia
Intervention:   Procedure: haemodialysis
Sponsors:   The George Institute;   National Health and Medical Research Council, Australia;   Baxter Healthcare Corporation
Completed - verified June 2013

Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence

Conditions:   Ischemic Stroke;   Patent Foramen Ovale;   Atrial Septal Aneurysm;   Migraine
Interventions:   Drug: aspirin;   Drug: Antivitamins K;   Device: Devices for PFO closure
Sponsor:   Assistance Publique - Hôpitaux de Paris
Active, not recruiting - verified June 2015

Cardiology Biobank Registry

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   Emory University
Recruiting - verified June 2015

The Effect of Different Schedules of Functional Task Practice for Improving Hand and Arm Function After Stroke

Conditions:   Cerebrovascular Accident;   Hemiplegia
Interventions:   Behavioral: functional task practice - distributed;   Behavioral: functional task practice - condensed
Sponsor:   Department of Veterans Affairs
Withdrawn - verified June 2015

PreFER Managed Ventricular Pacing (MVP) For Elective Replacement

Condition:   Cardiovascular Diseases
Intervention:   Device: Managed Ventricular Pacing programmed ON/OFF
Sponsor:   Medtronic Bakken Research Center
Completed - verified June 2015

Sleep Apnea: Mechanism and Cerebrovascular Consequences

Conditions:   Sleep Apnea, Obstructive;   Stroke
Intervention:   Drug: acetazolamide
Sponsor:   Department of Veterans Affairs
Withdrawn - verified June 2015

Screening and Natural History: Primary Lateral Sclerosis and Related Disorders

Conditions:   Motor Nueron Disease;   Nervous System Diseases;   Muscle Spasticity;   Diffusion Tensor Imaging;   Disease Progression;   Evoked Potentials, Motor/Physiology
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified September 2014

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