Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

The Safety and Efficacy Study of High Dose Atorvastatin After Thrombolytic Treatment in Acute Ischemic Stroke

Condition:   Stroke
Intervention:   Device: atorvastatin
Sponsors:   Second Affiliated Hospital, School of Medicine, Zhejiang University;   First Hospital of Jilin University
Recruiting - verified May 2015

Unilateral vs. Bilateral Approaches to Hybrid Stroke Rehabilitation

Condition:   Stroke
Interventions:   Procedure: Unilateral Hybrid Intervention;   Procedure: Bilateral Hybrid Intervention;   Device: BMT robot;   Other: Training
Sponsor:   Chang Gung Memorial Hospital
Not yet recruiting - verified April 2015

Clinical and Laboratory Biomarkers in Patients With Atherothrombotic Stroke

Conditions:   Carotid Artery Diseases;   Stroke
Intervention:   Other: Biomarkers serum level measurement
Sponsor:   St. Petersburg State Pavlov Medical University
Recruiting - verified January 2015

In Vivo Imaging of Therapeutic Electric Current Flow

Conditions:   Parkinson Disease;   Epilepsy;   Alzheimer's Disease;   Stroke;   Autism;   Depression;   Schizophrenia
Interventions:   Device: Transcranial direct current stimulation;   Procedure: MRI
Sponsors:   University of Florida;   Arizona State University;   National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - verified May 2015

Connected Health Blood Pressure Monitoring In Stroke and TIA Patients

Conditions:   Stroke;   Ischemic Attack, Transient
Intervention:   Other: Social incentive
Sponsor:   University of Pennsylvania
Not yet recruiting - verified May 2015

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion Pharmaceuticals, Inc.
Not yet recruiting - verified May 2015

Helping Stroke Patients With ThermoSuit Cooling

Conditions:   Stroke;   Brain Ischemia
Interventions:   Device: ThermoSuit Cooling Induction;   Drug: Magnesium Sulfate;   Drug: tPA;   Drug: Propofol;   Drug: Etomidate
Sponsors:   Life Recovery Systems;   Tulane University School of Medicine;   CHRISTUS Health
Not yet recruiting - verified May 2015

Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS

Conditions:   Brain Injury;   Central Nervous System Degenerative Disorder;   Central Nervous System Infectious Disorder;   Central Nervous System Vascular Malformation;   Hemorrhagic Cerebrovascular Accident;   Ischemic Cerebrovascular Accident;   Primary Brain Neoplasm;   Brain Cancer;   Brain Tumors
Interventions:   Drug: Ferumoxytol;   Other: Tissue Analysis;   Procedure: Magnetic Resonance Imaging
Sponsors:   Michael Iv;   National Cancer Institute (NCI)
Not yet recruiting - verified May 2015

Safety and Feasibility of Argatroban, Tissue Plasminogen Activator and Intra-arterial Therapy in Stroke

Conditions:   Stroke;   Cerebral Ischemia
Intervention:   Drug: Argatroban
Sponsor:   The University of Texas Health Science Center, Houston
Not yet recruiting - verified May 2015

Rivaroxaban Evaluation in Real Life Settings

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsors:   Thrombosis Research Institute;   Bayer
Recruiting - verified May 2015

Quality of Life After Stroke Using a Telemedicine-based Stroke Network

Condition:   Stroke
Intervention:   Drug: Alteplase
Sponsors:   Thomas Jefferson University;   Genentech, Inc.
Recruiting - verified May 2015

Optimizing Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke

Conditions:   Stroke;   Ischemic Stroke
Intervention:   Device: Mechanical Thrombectomy
Sponsor:   The University of Texas Health Science Center, Houston
Not yet recruiting - verified May 2015

Cognitive Impact of Pomegranate Polyphenols Following Ischemic Stroke

Condition:   Stroke
Interventions:   Dietary Supplement: POMx;   Other: Placebo
Sponsor:   Loma Linda University
Not yet recruiting - verified May 2015

Computer-Aided Prevention System

Conditions:   Cerebrovascular Diseases;   Stroke;   Cardiovascular Diseases;   CVD Risk Factors
Interventions:   Behavioral: Standard care;   Behavioral: CAPSYS
Sponsors:   Lübomira Spassova;   Centre Hospitalier du Luxembourg
Completed - verified May 2015

Coagulation Activity and Thrombogenesis in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: circumferential ablation;   Device: SVT ablation
Sponsor:   Tel-Aviv Sourasky Medical Center
Not yet recruiting - verified May 2015

Cardiovascular Epidemiology in Russian Federation

Conditions:   Hypertension;   Coronary Artery Disease;   Diabetes;   Heart Failure;   Smoking;   Lifestyle
Intervention:  
Sponsors:   Federal North-West Medical Research Centre;   National Research Center for Preventive Medicine;   Russian Cardiology Research and Production Center
Recruiting - verified May 2015

Ultrasound-guided Intermediate Cervical Plexus Block for Carotid Surgery

Condition:   Carotid Artery Stenosis
Intervention:   Procedure: Ultrasound-guided intermediate cervical plexus block
Sponsor:   Institut Mutualiste Montsouris
Completed - verified May 2015

Functional Connectivity In Relation To Proprioception and Sensorimotor Recovery in Stroke Patients (Feasibility Study)

Condition:   Stroke
Interventions:   Device: 3T scanner;   Device: Inactive transcutaneous electrical nerve stimulation (TENS);   Other: The exercises with the robot
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - verified May 2015

Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome

Conditions:   Cardiac Death;   Hemorrhage;   Cerebrovascular Accident;   Myocardial Infarction
Interventions:   Device: BES (biodegradable polymer biolimus-eluting stent);   Drug: Prasugel;   Drug: Clopidogrel
Sponsor:   Chonnam National University Hospital
Recruiting - verified May 2015

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Recruiting - verified May 2015

Non-invasive Measurement of Cerebral Dynamic Autoregulation

Condition:   Stroke
Intervention:   Device: Thigh Cuff
Sponsor:   University of Pennsylvania
Not yet recruiting - verified May 2015

Effects of Nicorandil on Cardiac Infarct Size in Patients With ST-segment Elevation Acute Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Drug: Nicorandil
Sponsors:   Pusan National University Hospital;   JW Pharmaceutical
Recruiting - verified May 2015

Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients

Condition:   Osteoarthrosis
Interventions:   Drug: Methylprednisolone;   Drug: Isotonic Sodium Chloride
Sponsors:   Rigshospitalet, Denmark;   Bispebjerg Hospital
Not yet recruiting - verified May 2015

Effects of Home-based Mirror Therapy Combined With Task-oriented Training for Patients With Stroke

Condition:   Stroke
Interventions:   Behavioral: home-based therapy;   Behavioral: hospital-based therapy
Sponsor:   Chang Gung Memorial Hospital
Not yet recruiting - verified April 2015

HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)

Condition:   Amyotrophic Lateral Sclerosis
Interventions:   Drug: Darunavir;   Drug: Ritonavir;   Drug: Raltegravir;   Drug: Zidovudine
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - verified April 2015

Amplatzer™Amulet™ Post-Market Study

Conditions:   Atrial Fibrillation;   Thromboembolism;   Stroke
Intervention:   Device: Subjects implanted with Amulet Device
Sponsor:   St. Jude Medical
Active, not recruiting - verified May 2015

Safety Study of Human Umbilical Cord Blood Monocyte in the Acute Ischemic Stroke Patients

Conditions:   Acute Stroke;   Brain Ischemia;   Ischemia;   Infarction, Middle Cerebral Artery
Intervention:   Biological: Intravenous Human Umbilical Cord Blood Monocyte
Sponsors:   China Medical University Hospital;   StemCyte, Inc.;   University of South Florida;   Saneron CCEL Therapeutics, Inc.;   Dr. Chih-Shan Hsu
Recruiting - verified May 2015

Administration of CBG000592 (Riboflavin/Vitamin B2) in Patients With Acute Ischemic Stroke

Condition:   Ischemic Stroke
Interventions:   Drug: Vitamin B2 Streuli®;   Other: Solution for injection
Sponsor:   Castillo, José, M.D.
Recruiting - verified May 2015

Corticospinal Function After SCI

Condition:   Spinal Cord Injury
Interventions:   Other: Electrophysiology Assessment of Time Domain;   Other: Electrophysiology Assessment of Location;   Other: Training with non-invasive strategy;   Other: Training with some stimulation
Sponsors:   University of Miami;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2015

Neural Control of Bilateral Movements After SCI

Condition:   Spinal Cord Injury
Interventions:   Device: Magstim 200;   Device: Digitimer electrical stimulator
Sponsors:   University of Miami;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2015

Hybrid Versus Catheter Ablation in Persistent AF

Condition:   Atrial Fibrillation
Interventions:   Procedure: Hybrid Ablation;   Procedure: Catheter Ablation
Sponsors:   Maastricht University Medical Center;   AtriCure, Inc.
Not yet recruiting - verified May 2015

Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis

Condition:   Asymptomatic Severe Aortic Stenosis
Intervention:   Procedure: surgical aortic valve replacement
Sponsor:   Clinical Centre of Serbia
Not yet recruiting - verified May 2015

Evaluation the Effectiveness of the Risk Minimisation Activities in the Treatment of Stroke Prevention in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2015

CRIC-Visceral Adiposity and Physical Fitness in Chronic Kidney Disease

Conditions:   Renal Insufficiency, Chronic;   Obesity
Intervention:  
Sponsors:   The Cleveland Clinic;   University of Pennsylvania;   Case Western Reserve University;   University of Michigan;   University of Illinois at Chicago;   University of Maryland;   MetroHealth Medical Center
Recruiting - verified April 2015

Self Directed Stations for the Stroke Patient

Condition:   Stroke
Intervention:   Other: Patient Directed Exercise Group
Sponsor:   Baylor Research Institute
Recruiting - verified May 2015

Influence on Plasticity of Brain Temperature

Condition:   Healthly Volunteers
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified April 2015

Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)

Conditions:   FTLD;   Progressive Supranuclear Palsy (PSP);   Frontotemporal Dementia (FTD);   Corticobasal Degeneration (CBD);   PPA Syndrome;   Behavioral Variant Frontotemporal Dementia (bvFTD);   Semantic Variant Primary Progressive Aphasia (svPPA);   Nonfluent Variant Primary Progressive Aphasia (nfvPPA);   FTD With Amyotrophic Lateral Sclerosis (FTD/ALS);   Amyotrophic Lateral Sclerosis (ALS);   Oligosymptomatic PSP (oPSP);   Corticobasal Syndrome (CBS)
Intervention:  
Sponsors:   University of California, San Francisco;   National Center for Advancing Translational Science (NCATS);   National Institute of Neurological Disorders and Stroke (NINDS);   The Bluefield Project to cure frontotemporal dementia;   Tau Consortium
Recruiting - verified May 2015

Uninterrupted Dabigatran Etexilate in Comparison to Uninterrupted Warfarin in Pulmonary Vein Ablation (RE-CIRCUIT)

Condition:   Atrial Fibrillation
Interventions:   Drug: Warfarin;   Drug: Dabigatran Etexilate 150mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2015

Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Procedure: Computed tomography angiography (cardiac CT);   Procedure: Invasive coronary angiography (ICA)
Sponsor:   Charite University, Berlin, Germany
Not yet recruiting - verified May 2015

Role of PPAR-y Anonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)

Condition:   Systemic Lupus Erthematosus
Interventions:   Radiation: PET/CT;   Drug: Pioglitazone;   Procedure: Vascular function studies
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified December 2014

The preDIlatation in tRanscathEter aortiC Valve implanTation Trial

Condition:   Aortic Valve Stenosis
Interventions:   Device: balloon aortic valvuloplasty;   Device: Transcatheter Aortic Valve Implantation
Sponsor:   University of Athens
Recruiting - verified May 2015

Phenotype, Genotype & Biomarkers in ALS and Related Disorders

Conditions:   Amyotrophic Lateral Sclerosis;   Frontotemporal Dementia;   Primary Lateral Sclerosis;   Hereditary Spastic Paraplegia;   Progressive Muscular Atrophy;   Multisystem Proteinopathy
Intervention:  
Sponsors:   University of Miami;   National Institute of Neurological Disorders and Stroke (NINDS);   National Center for Advancing Translational Science (NCATS);   St. Jude Children's Research Hospital
Recruiting - verified May 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Effects of Neuromodulation on Verbal Fluency in Post-stroke Aphasia

Condition:   Post-stroke Aphasia
Intervention:   Device: TNM(trademark) - thermoneuromodulation
Sponsors:   Scion NeuroStim;   Duke University
Recruiting - verified May 2015

Children With Diabetes at Risk for Heart Disease.

Conditions:   Diabetes Mellitus, Type 1;   Diabetes Complications
Intervention:  
Sponsors:   Georgetown University;   Howard University
Recruiting - verified May 2015

Evaluation of a New Calibrated Pulse Wave Analysis Method(EV1000™/volumeView™) for Cardiac Output Monitoring in Adult Liver Transplantation

Condition:   Liver Disease
Intervention:   Device: EV1000™/volumeView™
Sponsor:   Samsung Medical Center
Recruiting - verified May 2015

Program for the Identification of "Actionable" Atrial Fibrillation in the Family Practice Setting

Condition:   Atrial Fibrillation
Interventions:   Other: 30 Second Pulse Check;   Device: Watch BP Home A;   Device: HeartCheck Hand-held ECG device
Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified May 2015

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2015

Safety Evaluation of 3K3A-APC in Ischemic Stroke

Condition:   Ischemic Stroke
Interventions:   Biological: 3K3A-APC;   Drug: Placebo
Sponsors:   ZZ Biotech, LLC;   National Institute of Neurological Disorders and Stroke (NINDS);   Cedars-Sinai Medical Center;   Massachusetts General Hospital;   University of Iowa
Recruiting - verified May 2015

Effects of Donepezil on Regional Cerebral Blood Flow Following Aneurysmal Subarachnoid Haemorrhage

Conditions:   Aneurysmal Subarachnoid Hemorrhage;   Delayed Neurological Deficit;   Delayed Cerebral Ischemia;   Vasospasm
Intervention:   Drug: Donepezil
Sponsor:   St George's, University of London
Recruiting - verified May 2015

The Effects of tDCS Combined With Balance Training on Postural Control and Spasticity in Chronic Stroke Patients

Conditions:   Ischemic Stroke;   Spastic Gait
Interventions:   Device: Trance cranial direct current stimulation (tDCS);   Device: Sham
Sponsor:   Shahid Beheshti Medical University
Recruiting - verified August 2014

Changes in Cardiac Output During Delayed Umbilical Cord Clamping

Condition:   Cardiac Output, Low
Intervention:  
Sponsor:   Sharp HealthCare
Completed - verified August 2014

Refinement and Clinical Evaluation of the H-Man for Arm Rehabilitation After Stroke

Condition:   Stroke
Interventions:   Device: H-Man;   Other: Additional Conventional Therapy
Sponsors:   Tan Tock Seng Hospital;   National Medical Research Council (NMRC), Singapore
Recruiting - verified May 2015

Diuretic Comparison Project

Condition:   Hypertension
Interventions:   Drug: Hydrochlorothiazide;   Drug: Chlorthalidone
Sponsor:   Department of Veterans Affairs
Not yet recruiting - verified May 2015

Efficacy of Isradipine in Early Parkinson Disease

Condition:   Parkinson Disease
Interventions:   Drug: Isradipine;   Drug: Placebo (for Isradipine)
Sponsors:   University of Rochester;   National Institute of Neurological Disorders and Stroke (NINDS);   Michael J. Fox Foundation for Parkinson's Research
Recruiting - verified May 2015

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Recruiting - verified April 2015

Pilot Investigation of Stem Cells in Stroke Phase II Efficacy

Conditions:   Ischaemic Stroke;   Cerebral Infarction;   Hemiparesis;   Arm Paralysis
Intervention:   Biological: CTX DP
Sponsor:   ReNeuron Limited
Recruiting - verified May 2015

Metabolic Costs of Walking Post Stroke

Condition:   Acute Stroke
Interventions:   Other: ESTT;   Other: Traditional outpatient
Sponsor:   University of Texas Southwestern Medical Center
Recruiting - verified July 2014

Evaluation of Physical Therapy Interventions and Patient Characteristics on Outcomes

Condition:   Acute Stroke
Intervention:  
Sponsor:   University of Texas Southwestern Medical Center
Withdrawn - verified May 2015

Emotional Communication Disorders in Cerebellar Disease

Condition:   Cerebellar Diseases
Interventions:   Behavioral: Testing of emotional communication ability;   Procedure: magnetic resonance imaging (MRI) of the brain
Sponsors:   University of Florida;   National Institute on Aging (NIA)
Recruiting - verified May 2015

Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)

Conditions:   Charcot Marie Tooth Disease;   Inherited Peripheral Neuropathy
Intervention:  
Sponsors:   University of Iowa;   National Institute of Neurological Disorders and Stroke (NINDS);   Charcot-Marie-Tooth Association;   Muscular Dystrophy Association;   University of Rochester;   University of South Florida
Recruiting - verified May 2015

Efficacy and Safety Study of rTMS for Upper Extremity Motor Function Recovery in Ischemic Stroke Patients

Conditions:   Stroke;   Hemiplegia
Intervention:   Device: Low frequency rTMS
Sponsors:   Seoul National University Bundang Hospital;   DongGuk University
Recruiting - verified May 2015

Mobility Training Using Exoskeletons for Functional Recovery After Stroke

Condition:   Severe Stroke or Similar Neurological Muscle Weakness
Intervention:   Device: Ekso exoskeleton
Sponsors:   Rehabilitation Institute of Chicago;   U.S. Department of Education
Recruiting - verified May 2015

Kinect-based Upper Limb Rehabilitation System in Stroke Patients

Conditions:   Stroke;   Hemiplegia;   Virtual Rehabilitation
Interventions:   Procedure: Kinect-based rehabilitation plus occupational therapy;   Other: sham virtual rehabilitation education plus occupational therapy
Sponsors:   Seoul National University Bundang Hospital;   Microsoft Research Asia;   The Ministry of Science, ICT and Future Planning
Recruiting - verified May 2015

Impact of Continuous Positive Airway Pressure (CPAP) Therapy on Outcomes in Patients Undergoing Coronary Revascularization

Conditions:   Obstructive Sleep Apnea;   Ischaemic Heart Desease
Intervention:   Device: CPAP
Sponsor:   Beijing Anzhen Hospital
Recruiting - verified March 2014

Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism)

Conditions:   Pulmonary Embolism;   Thromboembolism;   Thrombosis;   Venous Thrombosis;   Venous Thromboembolism
Interventions:   Drug: BAY 59-7939;   Drug: BAY 59-7939;   Drug: ASA
Sponsor:   Bayer
Recruiting - verified May 2015

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified May 2015

Transfusion Requirements in Cardiac Surgery III

Condition:   Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Interventions:   Other: Restrictive Transfusion Strategy;   Other: Liberal transfusion strategy
Sponsor:   St. Michael's Hospital, Toronto
Recruiting - verified May 2015

The Development of Upper Extremity Rehabilitation Program Using Virtual Reality for the Stroke Patients

Condition:   Upper Extremity Dysfunction After the Stroke
Interventions:   Other: Virtual reality program for upper extremity rehabilitation;   Other: standard occupational therapy
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified May 2015

VASSTII: An Exploratory Clinical Study on a Variable Speed and Sensing Treadmill System for Hemiparetic Gait Rehabilitation After Stroke

Conditions:   Stroke;   Hemiplegic Gait
Intervention:   Device: VASST
Sponsors:   Tan Tock Seng Hospital;   Ngee Ann Polytechnic
Recruiting - verified May 2015

[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]

Conditions:   Acute Ischaemic Stroke;   Transient Ischaemic Attack.
Interventions:   Drug: ticagrelor;   Drug: Acetylsalicylic acid (ASA)
Sponsor:   AstraZeneca
Recruiting - verified May 2015

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Ticagrelor 90 mg;   Drug: Ticagrelor placebo
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Development of Walk Assist Device to Improve Community Ambulation

Condition:   Stroke
Interventions:   Device: The Stride Management Assist (SMA) System;   Other: Impairment based therapy
Sponsors:   Rehabilitation Institute of Chicago;   Honda 
Active, not recruiting - verified May 2015

Cardiovascular Outcomes Following Treatment With Ertugliflozin in Participants With Type 2 Diabetes Mellitus and Established Vascular Disease (MK-8835-004)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Recruiting - verified May 2015

Ticagrelor in Severe Community Acquired Pneumonia

Condition:   Community Acquired Pneumonia, Severe
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   Gordon Bernard;   AstraZeneca
Recruiting - verified May 2015

Bolus of Saline in Stroke

Condition:   Ischemic Stroke
Intervention:   Other: Normal saline
Sponsor:   University of Pennsylvania
Recruiting - verified May 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2015

Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis

Conditions:   Multiple Sclerosis, Primary Progressive;   Multiple Sclerosis, Secondary Progressive
Interventions:   Drug: ibudilast;   Drug: Placebo
Sponsors:   MediciNova;   National Institutes of Health (NIH);   National Institute of Neurological Disorders and Stroke (NINDS);   National Multiple Sclerosis Society
Active, not recruiting - verified May 2015

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2015

Effect of Natalizumab on Infarct Volume in Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: natalizumab;   Drug: Placebo
Sponsor:   Biogen Idec
Completed - verified April 2015

Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Drug: Apixaban;   Drug: aspirin
Sponsors:   Population Health Research Institute;   Bristol-Myers Squibb;   Pfizer;   Medtronic
Recruiting - verified May 2015

Emotional Prosody Treatment in Parkinson's

Condition:   Parkinson Disease
Interventions:   Behavioral: Emotional prosodic treatment;   Behavioral: Standard prosodic treatment
Sponsor:   Department of Veterans Affairs
Recruiting - verified May 2015

Effects of Exercise on Memory in Healthy and Brain-Injured Individuals

Condition:   Traumatic Brain Injury
Interventions:   Other: Exercise - Low-intensity exercise;   Other: Exercise - High-intensity exercise
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified June 2014

Risk of Stroke and Silent Cerebrovascular Thromboembolism After Cardioversion of Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Cardioversion;   Cerebrovascular Stroke
Interventions:   Procedure: Cardioversion;   Drug: warfarin
Sponsor:   Suleyman Demirel University
Recruiting - verified October 2014

Blood Pressure Variability in Acute Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:  
Sponsors:   Aristotle University Of Thessaloniki;   A & D Company Limited 
Recruiting - verified May 2015

Study of GSK1278863 to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm Repair

Condition:   Surgical Procedures
Interventions:   Drug: GSK1278863;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Active, not recruiting - verified April 2015

Non-interventional Local Study on Prescription Behavior of Anticoagulation Therapy in Secondary Stroke Prevention in Atrial Fibrillation Patients

Conditions:   Stroke,;   Embolism
Intervention:   Other: Rivaroxaban ( Xarelto, BAY59-7939)
Sponsor:   Bayer
Active, not recruiting - verified May 2015

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified May 2015

Determining the Effect of Abacavir on Platelet Activation

Conditions:   HIV;   Cardiovascular Disease
Intervention:   Drug: Abacavir
Sponsor:   Bayside Health
Completed - verified May 2015

Thinking and Memory Problems in People With HIV

Conditions:   Acquired Immunodeficiency;   Neurocognitive Disorders
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified January 2015

Observational Study of Ischaemic Stroke

Conditions:   Stroke;   Motor Activity
Intervention:  
Sponsor:   ReNeuron Limited
Recruiting - verified May 2015

Belgian Real Life Non-interventional Study (NIS) on Xarelto in Non-valvular Atrial Fibrillation (AF) Patients Treated for the Prevention of Stroke and Systemic Embolism

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Completed - verified May 2015

Reperfusion of Pulmonary Arteriovenous Malformations After Embolotherapy

Condition:   Pulmonary Arteriovenous Malformations
Intervention:   Procedure: Angiography and embolotherapy
Sponsor:   St. Michael's Hospital, Toronto
Recruiting - verified May 2015

Natural History of Optic Neuritis

Condition:   Multiple Sclerosis
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Neurological Disorders and Stroke (NINDS);   National Eye Institute (NEI)
Suspended - verified December 2014

Skeletal Muscle Biomarkers in People With Fragile Sarcolemmal Muscular Dystrophy

Condition:   Genetic Disorder
Intervention:  
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Neurological Disorders and Stroke (NINDS);   National Institutes of Health Clinical Center (CC);   University of Massachusetts, Worcester
Recruiting - verified January 2015

iPad Technology for HOME Rehabilitation in Patients After Stroke: iHOME Acute/Chronic

Condition:   Fine Motor Function Deficit and Visual Neglect Post-stroke
Interventions:   Other: iPad Intervention;   Other: Standard/ Usual Care
Sponsors:   St. Michael's Hospital, Toronto;   Sunnybrook Research Institute
Recruiting - verified May 2015

Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) Over the Brain on the Neurotransmitter Binding

Conditions:   Stroke;   Hemiplegia
Interventions:   Device: Low frequency rTMS;   Device: High frequency rTMS;   Device: Sham rTMS
Sponsors:   Seoul National University Bundang Hospital;   Ministry of Health & Welfare, Korea
Suspended - verified May 2015

Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion

Conditions:   Head Injury;   Intracranial Pathology;   Compromised Cerebral Perfusion
Intervention:   Device: ITPR
Sponsors:   Advanced Circulatory Systems;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2015

A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: rivaroxaban 2.5 mg;   Drug: rivaroxaban 15 mg;   Drug: rivaroxaban 10 mg;   Drug: aspirin (ASA);   Drug: vitamin K antagonist (VKA);   Drug: clopidogrel;   Drug: prasugrel;   Drug: ticagrelor
Sponsors:   Janssen Scientific Affairs, LLC;   Bayer
Recruiting - verified May 2015

Study Evaluating the Safety,Tolerability and Efficacy of PF-04360365 in Adults With Probable Cerebral Amyloid Angiopathy

Condition:   Cerebral Amyloid Angiopathy
Interventions:   Biological: Ponezumab;   Other: placebo
Sponsor:   Pfizer
Active, not recruiting - verified May 2015

The Sunnybrook Dementia Study: Mapping Brain Changes in Alzheimer's, Vascular and Other Dementias

Condition:   Dementia
Intervention:  
Sponsors:   Sunnybrook Health Sciences Centre;   University of Toronto;   Sunnybrook Research Institute;   University of Waterloo;   Baycrest
Active, not recruiting - verified May 2015

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified May 2015

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Recruiting - verified May 2015

Right to Left Cardiac Shunt Detection

Conditions:   Right to Left Shunt;   Patent Foramen Ovale;   Atrial Septal Defect
Intervention:   Device: Flow Detection System
Sponsor:   Cardiox Corporation
Recruiting - verified May 2015

Permeability MRI in Cerebral Cavernous Malformations Type 1 in New Mexico: Effects of Statins

Conditions:   Cavernous Angioma, Familial;   Cerebral Cavernous Malformations;   Cerebral Cavernous Hemangioma
Intervention:   Drug: Simvastatin
Sponsors:   University of New Mexico;   National Institute of Neurological Disorders and Stroke (NINDS);   University of California, San Francisco
Recruiting - verified May 2015

Assessment and Management of Post-Stroke Spasticity With Botulinum Toxin-A

Conditions:   Stroke;   Muscle Spasticity
Interventions:   Behavioral: Optimal muscle activation therapy;   Behavioral: Standard Therapy
Sponsors:   Sunnybrook Health Sciences Centre;   Allergan
Completed - verified May 2015

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Asia

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified May 2015

Topical Anti-angiogenic Therapy for Telangiectasia in HHT: Proof of Concept

Condition:   Hereditary Hemorrhagic Telangiectasia (HHT).
Interventions:   Drug: Topical timolol maleate;   Drug: placebo saline drops
Sponsors:   St. Michael's Hospital, Toronto;   University of California, San Francisco;   The Hospital for Sick Children;   University of Toronto;   Sunnybrook Health Sciences Centre;   Ryerson University;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2015

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified May 2015

Sunnaas International Network´s Stroke Study

Condition:   Cerebral Stroke
Intervention:   Other: rehabilitation
Sponsors:   Sunnaas Rehabilitation Hospital;   China Rehabilitation Research Center;   Sichuan 81 Rehabilitation Center, Chengdu;   NYU Langoon medical center; The Rusk Institute of Rehabilitation Medicine, New York;   City outpatient clinics №2,Petrozavodsk, Petrozavodsk;   Sheba Medical Center;   El Wafa rehabilitation hospital, Gaza;   Bethlehem Arab Society for Rehabilitation, Betlehem;   Sahlgrenska University Hospital, Sweden
Active, not recruiting - verified May 2015

The General Use of Robots in Stroke Recovery

Condition:   Stroke
Intervention:   Device: IMT Robotic Arm therapy
Sponsor:   North Shore Long Island Jewish Health System
Not yet recruiting - verified May 2015

Does Tranexamic Acid Reduce the Need for Blood Transfusions in Patients Undergoing Hip Fracture Surgery?

Condition:   Hip Fracture
Intervention:   Drug: tranexamic acid
Sponsor:   Mayo Clinic
Active, not recruiting - verified May 2015

Evaluation of the Phased Radio Frequency Ablation System

Condition:   Persistent Atrial Fibrillation
Intervention:   Device: Medtronic Phased RF Ablation System
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified May 2015

Brain Stimulation and Aphasia Treatment

Condition:   Aphasia
Interventions:   Device: Activa Dose II Real tDCS;   Device: Activa Dose II Sham tDCS
Sponsors:   University of South Carolina;   National Institute on Deafness and Other Communication Disorders (NIDCD);   Medical University of South Carolina
Recruiting - verified May 2015

Computed Tomography Perfusion (CTP) to Predict Response to Recanalization in Ischemic Stroke Project (CRISP)

Condition:   Stroke
Intervention:  
Sponsors:   Stanford University;   Saint Luke's Health System;   University of Pittsburgh;   Emory University;   Chatanooga Center for Neurological Research;   University of Miami
Recruiting - verified May 2015

China PEACE-Prospective PCI Study

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   China National Center for Cardiovascular Diseases;   Ministry of Health, China
Active, not recruiting - verified May 2015

China PEACE-Prospective AMI Study

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   China National Center for Cardiovascular Diseases;   Ministry of Health, China
Active, not recruiting - verified May 2015

Non-invasive Neurostimulation in Parkinson's Disease

Condition:   Parkinson's Disease
Interventions:   Procedure: low-intensity transcranial electrical stimulation;   Procedure: transcranial ultrasound
Sponsors:   Spaulding Rehabilitation Hospital;   National Institute of Neurological Disorders and Stroke (NINDS);   Highland Instruments, Inc.
Recruiting - verified May 2015

Xarelto [SPAF-QOL] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban (Xarelto_ BAY59-7939)
Sponsor:   Bayer
Recruiting - verified May 2015

Xarelto [SPAF] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban(Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified May 2015

Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders.

Condition:   Smoking Cessation
Interventions:   Drug: placebo;   Drug: varenicline tartrate;   Drug: bupropion hydrochloride;   Drug: Nicotine Replacement Therapy Patch
Sponsor:   Pfizer
Active, not recruiting - verified May 2015

Ponatinib - Frontline for Chronic Myeloid Leukemia (CML) in Accelerated Phase (AP)

Condition:   Leukemia
Intervention:   Drug: Ponatinib
Sponsors:   M.D. Anderson Cancer Center;   Ariad Pharmaceuticals
Active, not recruiting - verified May 2015

LiDCO Monitor Study

Condition:   Cardiac Surgery
Intervention:   Device: LiDCO rapid monitor
Sponsor:   Nationwide Children's Hospital
Completed - verified May 2015

Neurovascular Non Contrast-Enhanced MR Angiography at 3T

Condition:   Neurovascular Diseases
Intervention:  
Sponsor:   Rennes University Hospital
Recruiting - verified May 2015

Prospective Study of Clinically Nonfunctioning Pituitary Adenomas

Conditions:   Pituitary Adenoma;   Pituitary Tumor
Interventions:   Procedure: Surgical intervention for CNFA;   Radiation: Radiotherapy for CNFA
Sponsors:   Columbia University;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2015

Valvuloplasty Scoring Balloon Catheter First-in-Man Study

Condition:   Aortic Valve Stenosis
Intervention:   Device: AngioScore's Valvuloplasty Scoring Balloon
Sponsor:   Spectranetics Corporation
Active, not recruiting - verified May 2015

Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Injection of Cyclosporin;   Drug: Placebo;   Procedure: Echocardiography
Sponsor:   Hospices Civils de Lyon
Active, not recruiting - verified April 2015

Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resistant Movement Disorders

Condition:   Obsessive-Complusive Disorder
Intervention:  
Sponsors:   National Institute of Neurological Disorders and Stroke (NINDS);   George Washington University
Recruiting - verified April 2015

Effects of Hormone Stimulation on Brain Scans for Cushing s Disease

Condition:   Pituitary Neoplasm
Intervention:   Drug: Acthrel
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2014

Studying Skeletal Muscle, Heart, and Diaphragm Imaging in Boys With Duchenne Muscular Dystrophy

Conditions:   Muscular Dystrophy;   Muscular Disease
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified May 2014

Vernakalant Versus Ibutilide In Recent-Onset Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Drug: Brinavess (Vernakalant);   Drug: Corvert (Ibutilide)
Sponsor:   Medical University of Vienna
Completed - verified May 2015

Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)

Condition:   Atherosclerosis
Interventions:   Drug: Canakinumab;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting - verified May 2015

Effects of the Quantity of Repetitive Transcranial Magnetic Stimulation(rTMS) on the Recovery After Stroke

Conditions:   Stroke;   Hemiplegia
Intervention:   Device: repetitive transcranial magnetic stimulation (rTMS)
Sponsors:   Seoul National University Bundang Hospital;   Asan Medical Center;   Gyeongsang National University Hospital;   Hanyang University;   Seoul National University Boramae Hospital
Terminated - verified May 2015

Carotid Plaque Imaging in Acute Stroke

Conditions:   Stroke;   Ischemic Attack, Transient
Intervention:  
Sponsors:   Ludwig-Maximilians - University of Munich;   Technische Universität München
Recruiting - verified May 2015

PRX-00023 Therapy in Localization-Related Epilepsy

Conditions:   Epilepsy;   Epilepsy, Temporal Lobe;   Partial Epilepsy
Intervention:   Drug: PRX-00023
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified April 2015

Mobility Training to Improve Motor Behavior in Toddlers With or at Risk for Cerebral Palsy: A Pilot Study

Conditions:   Developmental Delay;   Cerebral Palsy
Intervention:   Behavioral: mobility training with dynamic body weight support
Sponsor:   National Institutes of Health Clinical Center (CC)
Completed - verified April 2015

Mediators of Atherosclerosis in South Asians Living in America

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Coronary Artery Disease;   Coronary Disease
Intervention:  
Sponsors:   University of California, San Francisco;   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified May 2015

Study of Cobalt's Role in Excessive Erythrocytosis Among High Altitude Dwellers in Cerro de Pasco, Peru

Conditions:   Erythrocytosis;   Mountain Sickness
Interventions:   Drug: N-acetylcysteine;   Drug: Acetazolamide;   Drug: Placebo pills
Sponsors:   University of Colorado, Denver;   Abdias Hurtado, Elizabeth Escudero (Universidad Peruana Cayetano Heredia);   Jackson, Brian, M.S.;   Thomas H Maren Foundation
Completed - verified May 2015

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

Condition:   Charcot Marie Tooth Disease
Intervention:  
Sponsors:   University of Iowa;   Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta;   Johns Hopkins University;   National Institute of Neurological Disorders and Stroke (NINDS);   King's College Hospital NHS Trust;   Nemours Children's Clinic;   Stanford University;   University of Pennsylvania;   University of Rochester;   University of Washington;   Vanderbilt University;   Children's Hospital of Philadelphia;   The Children's Hospital at Westmead;   Rare Diseases Clinical Research Network;   Muscular Dystrophy Association;   National Institutes of Health (NIH);   Charcot-Marie-Tooth Association;   University of Michigan;   Massachusetts General Hospital;   Cedars-Sinai Medical Center
Recruiting - verified May 2015

Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT

Condition:   Charcot Marie Tooth Disease
Intervention:  
Sponsors:   University of Iowa;   National Institute of Neurological Disorders and Stroke (NINDS);   Muscular Dystrophy Association;   University of Rochester;   Children's Hospital of Philadelphia;   University College London Hospitals;   Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta;   The Children's Hospital at Westmead;   Nemours Children's Clinic
Recruiting - verified May 2015

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

Conditions:   Charcot-Marie-Tooth Disease, Type Ia (Disorder);   HMSN
Intervention:  
Sponsors:   University of Iowa;   National Institute of Neurological Disorders and Stroke (NINDS);   Muscular Dystrophy Association;   University of Rochester;   University of Pennsylvania;   King's College Hospital NHS Trust;   The Children's Hospital at Westmead;   Children's Hospital of Philadelphia;   University of Miami;   Johns Hopkins University;   University of Washington;   Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta;   Cedars-Sinai Medical Center;   Nemours Children's Clinic;   Stanford University;   University of Michigan;   Vanderbilt University
Recruiting - verified May 2015

Pilot Investigation of Stem Cells in Stroke

Condition:   Stroke
Intervention:   Biological: CTX0E03 neural stem cells
Sponsor:   ReNeuron Limited
Active, not recruiting - verified May 2015

The Intravascular Cooling in the Treatment of Stroke 2/3 Trial

Condition:   Stroke, Acute
Interventions:   Device: hypothermia;   Other: Group1: IV t-PA and normothermia
Sponsors:   University of California, San Diego;   National Institute of Neurological Disorders and Stroke (NINDS)
Terminated - verified May 2015

The Role of Endothelin in the Supine Hypertension of Autonomic Failure

Conditions:   Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions:   Drug: BQ123;   Drug: BQ123;   Drug: Bq123;   Drug: BQ123;   Drug: Saline
Sponsor:   Vanderbilt University
Recruiting - verified May 2015

CANVAS - CANagliflozin cardioVascular Assessment Study

Conditions:   Diabetes Mellitus, Type 2;   Cardiovascular Diseases;   Risk Factors
Interventions:   Drug: Canagliflozin (JNJ-28431754);   Drug: Placebo
Sponsors:   Janssen Research & Development, LLC;   The George Institute for Global Health, Australia
Active, not recruiting - verified May 2015

Follow Up Study for Treatment of Parkinson's Disease With Deep Brain Stimulation

Condition:   Parkinson Disease
Intervention:  
Sponsors:   Department of Veterans Affairs;   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified May 2015

Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer

Conditions:   Pain/Cancer;   Pain, Intractable
Interventions:   Drug: (Resiniferatoxin)(RTX);   Drug: Intrathecal Resiniferatoxin
Sponsors:   National Institute of Dental and Craniofacial Research (NIDCR);   National Institute of Neurological Disorders and Stroke (NINDS);   Sorrento Therapeutics, Inc.
Recruiting - verified July 2014

Clinical Biological and Pharmacological Factors Influencing Stroke Outcome

Condition:   Stroke
Intervention:  
Sponsors:   University Hospital, Lille;   Institut National de la Santé Et de la Recherche Médicale, France
Completed - verified May 2015

Trial of a Cardiac Rehabilitation Program Delivered Remotely Through the Internet

Condition:   Cardiovascular Disease
Intervention:   Behavioral: vCRP
Sponsors:   Simon Fraser University;   Heart and Stroke Foundation of Canada
Completed - verified May 2015

Insulin Resistance and Atherosclerosis in Women With Lupus

Conditions:   Systemic Lupus Erythematosus;   Insulin Resistance;   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed - verified May 2015

Hu Mik-Beta-1 to Treat HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis

Condition:   HTLV-1
Intervention:   Drug: Hu MiK-Beta-1
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Suspended - verified March 2015

Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo

Condition:   Epilepsies, Partial
Interventions:   Drug: Lyrica (pregabalin);   Drug: placebo
Sponsor:   Pfizer
Recruiting - verified May 2015

To Determine the Feasibility of a Clinical Trial Comparing Anticoagulants Versus Antiplatelets in the Acute Treatment of Patients With Cervical Artery Dissection

Conditions:   Cervical Artery Dissection;   Carotid Artery Dissection;   Vertebral Artery Dissection;   Stroke
Interventions:   Drug: Antiplatelet (Aspirin, Dipyridamole, clopidogrel);   Drug: Anticoagulant (Unfractionated Heparin, LMW Heparin, Warfarin)
Sponsors:   St George's, University of London;   The Stroke Association, United Kingdom
Completed - verified September 2005

Idebenone to Treat Friedreich's Ataxia

Condition:   Friedreich Ataxia
Intervention:   Drug: Idebenone
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified May 2015

Use of Low Molecular Weight Heparin (Tinzaparin) to Treat Blood Clots in Patients With Kidney Failure

Conditions:   Venous Thrombosis;   Pulmonary Embolism
Intervention:   Drug: Tinzaparin
Sponsors:   St. Joseph's Healthcare Hamilton;   Heart and Stroke Foundation of Ontario;   LEO Pharma
Recruiting - verified May 2015

Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack.

Conditions:   Ischemic Heart Failure;   Ischemic Heart Disease;   Ischemic Cardiomyopathy
Intervention:   Drug: Cellular Therapy (Cultured Autologous Skeletal Myoblast Transplantation)
Sponsor:   Genzyme, a Sanofi Company
Terminated - verified May 2015

Botulinum Toxin for the Treatment of Involuntary Movement Disorders

Conditions:   Chorea;   Drug Induced Dyskinesia;   Movement Disorder;   Muscular Disease;   Tic Disorder
Intervention:   Other: Botulinum Toxin
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified May 2015

Human Movement Database

Conditions:   Healthy;   Movement Disorder
Intervention:  
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified May 2015

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