Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Biomarkers for Prediction of Hand Function After Stroke - The ProHand Study

Conditions:   Stroke;   Hemiparesis
Intervention:  
Sponsor:   Danderyd Hospital
Recruiting - verified August 2016

Assessment of Patients' Early Neurological Clinical Recovery, 3 Months After Endovascular Treatment of an Acute Ischemic Stroke

Condition:   Stroke, Acute
Intervention:  
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified August 2016

AMPLATZER™ Amulet™ Left Atrial Appendage Occluder Randomized Controlled Trial

Condition:   Stroke
Interventions:   Device: Amulet Left Atrial Appendage Occluder;   Device: WATCHMAN Left Atrial Appendage Closure
Sponsor:   St. Jude Medical
Not yet recruiting - verified August 2016

Combining Non-Invasive Vagus Nerve Stimulation and Robotic Training in Upper Limb-Impaired Chronic Stroke Patients

Condition:   Stroke
Intervention:   Device: Transcutaneous vagal nerve stimulation
Sponsors:   Campus Bio-Medico University;   Biomedical Robotics and Biomicrosystems, Campus Bio-Medico University;   Physical and Rehabilitation Medicine, Campus Bio-Medico University
Recruiting - verified August 2016

Wristbot: A Novel Device for the Assessment of Proprioceptive Deficits After Stroke

Condition:   Stroke
Intervention:   Device: Wristbot
Sponsors:   Tan Tock Seng Hospital;   Nanyang Technological University
Not yet recruiting - verified August 2016

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D)

Condition:   Anaemia
Interventions:   Drug: Daprodustat;   Drug: rhEPO;   Drug: Placebo;   Drug: Iron therapy
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified August 2016

Robotic Mirror Therapy System for Functional Recovery of Hemiplegic Arms

Condition:   Stroke
Interventions:   Device: Robotic mirror therapy;   Device: Conventional mirror therapy
Sponsors:   Seoul National University Hospital;   Seoul National University College of Medicine
Recruiting - verified August 2016

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Non-Dialysis (ASCEND-ND)

Condition:   Anaemia
Interventions:   Drug: Daprodustat;   Drug: Darbepoetin alfa;   Drug: Placebo;   Drug: Iron Therapy
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified August 2016

Multi-segmental Robotic and Technological Upper Limb Rehabilitation in Stroke

Condition:   Stroke
Interventions:   Device: Amadeo, Pablo, Diego and Motore.;   Other: Conventional rehabilitation
Sponsor:   Fondazione Don Carlo Gnocchi Onlus
Recruiting - verified August 2016

Analysis of Stroke Rehabilitation Outcomes

Condition:   Stroke
Intervention:   Other: Observational - No intervention
Sponsor:   Weill Medical College of Cornell University
Active, not recruiting - verified August 2016

Berlin PRehospital Or Usual Delivery of Acute Stroke Care

Condition:   Stroke
Interventions:   Procedure: STEMO;   Procedure: Regular care
Sponsors:   Charite University, Berlin, Germany;   Center for Stroke Research Berlin
Recruiting - verified August 2016

Cortical Ischemic Stroke and Serotonin

Condition:   Stroke
Interventions:   Drug: Serotonin Uptake Inhibitors;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   Cantonal Hospital of St. Gallen
Recruiting - verified August 2016

China PEACE 5p-HF Study

Condition:   Heart Failure
Intervention:   Other: Observational study
Sponsor:   China National Center for Cardiovascular Diseases
Not yet recruiting - verified August 2016

Vinpocetine Inhibits NF-κB-dependent Inflammation in Acute Ischemic Stroke Patients

Conditions:   Stroke;   Immunoregulation;   Inflammation;   Vinpocetine
Interventions:   Drug: vinpocetine;   Drug: Aspirin
Sponsor:   Tianjin Medical University General Hospital
Completed - verified August 2016

Noninvasive Assessment of Neuronal Damage by MRI Sodium ( 23Na ) in Amyotrophic Lateral Sclerosis

Condition:   Amyotrophic Lateral Sclerosis
Intervention:   Other: sodium MRI
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified August 2016

Neurothrombectomy France

Condition:   Cerebral Artery Occlusion
Intervention:  
Sponsor:   Nantes University Hospital
Completed - verified August 2016

Comparative Efficacy Study of Action Observation Therapy and Mirror Therapy After Stroke

Condition:   Stroke
Interventions:   Behavioral: Action observation therapy;   Behavioral: Mirror therapy;   Behavioral: Customary bilateral UE training
Sponsor:   Chang Gung Memorial Hospital
Not yet recruiting - verified July 2016

Effect of Music on Reading Comprehension for Patients With Aphasia

Condition:   Aphasia
Interventions:   Behavioral: Simultaneous music and reading lyrics;   Behavioral: Priming with music;   Behavioral: Control
Sponsor:   Carilion Clinic
Enrolling by invitation - verified August 2016

Topiramate for Cryptogenic Sensory Peripheral Neuropathy

Condition:   Cryptogenic Sensory Peripheral Neuropathy
Interventions:   Drug: topiramate;   Other: Placebo
Sponsors:   University of Utah;   National Institute of Neurological Disorders and Stroke (NINDS);   NeuroNEXT Network
Not yet recruiting - verified August 2016

Evaluation of the Observance and the Tolerance of a Motor Training Program

Conditions:   Hemiplegia;   Stroke
Interventions:   Device: Active tDCS;   Device: Sham tDCS
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Not yet recruiting - verified August 2016

Impact of Sleep-disordered Breathing on Atrial Fibrillation and Perioperative Complications of Coronary Artery Bypass Grafting Surgery

Conditions:   Elective Coronary Artery Bypass Grafting (CABG) Surgery;   Coronary Artery Disease;   Sleep-disordered Breathing (SDB);   Atrial Fibrillation
Intervention:   Other: Stratification, no intervention
Sponsor:   Michael Arzt
Recruiting - verified August 2016

Efficacy and Safety Trial With S 44819 After Recent Ischemic Cerebral Event

Condition:   Post Stroke Recovery
Interventions:   Drug: S 44819 150 mg twice a day;   Drug: S 44819 300 mg twice a day;   Drug: Placebo
Sponsors:   Institut de Recherches Internationales Servier;   ADIR Association
Not yet recruiting - verified July 2016

Evaluating the Therapeutic Effect of Scalp Acupuncture Treatment for Motor Dysfunction in Ischemic Stroke Patients

Conditions:   Ischemic Stroke;   Hemiplegia
Interventions:   Device: Scalp Acupuncture Treatment;   Other: Rehabilitation treatment
Sponsors:   Shanghai University of Traditional Chinese Medicine;   Fudan University
Recruiting - verified June 2016

Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology

Conditions:   Pain;   Pneumoperitoneum;   Inflammation;   Quality of Life
Intervention:   Procedure: Pneumoinsufflator mode and setting
Sponsors:   Cleveland Clinic Florida;   ConMed Corporation
Not yet recruiting - verified August 2016

Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial

Conditions:   Intracranial Aneurysm;   Subarachnoid Hemorrhage
Interventions:   Drug: Deferoxamine;   Other: placebo
Sponsors:   Radboud University;   University Medical Center Groningen
Not yet recruiting - verified July 2016

Intraoperative Ultrasound in Laparoscopic or Robotic Myomectomy Patients

Conditions:   Fibroid Uterus;   Quality of Life
Intervention:   Procedure: Intraoperative contact ultrasonography
Sponsors:   Cleveland Clinic Florida;   BK Ultrasound
Recruiting - verified May 2016

Catalytic Antibodies to Predict Uninvasively Late Transplant Failure

Condition:   Renal Transplantation
Intervention:   Other: blood samples
Sponsor:   Hospices Civils de Lyon
Completed - verified August 2016

The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Stroke

Condition:   Ischemic Stroke
Interventions:   Drug: Byetta;   Drug: Normosaline
Sponsor:   Christina Kruuse
Active, not recruiting - verified August 2016

The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Non-stroke Volunteers

Condition:   Stroke
Interventions:   Drug: Byetta;   Drug: Isotonic saline
Sponsor:   Christina Kruuse
Enrolling by invitation - verified August 2016

PROspective Study to OPTimize thE HEALTH of Patients With TIAs (Transient Ischemic Attacks) and Stroke Admitted to the Hamad General Hospital

Conditions:   Stroke;   Transient Ischemic Attack (TIA)
Intervention:   Other: Aggressive Management
Sponsor:   Hamad Medical Corporation
Not yet recruiting - verified June 2016

CADASIL Disease Discovery

Conditions:   Cardiovascular Disease;   Arterial Stiffness
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

The Metabolism Research of KLK Treating Acute Cerebral Ischemic Stroke: Focus on Drug Frequency-Efficacy Relationship

Condition:   Cerebral Infarction
Intervention:   Drug: Human Urinary Kallidinogenase for Injection
Sponsor:   Huisheng Chen
Not yet recruiting - verified August 2016

Study of DU-176b Aged 80 Years or Older

Condition:   Atrial Fibrillation
Interventions:   Drug: Du-176b;   Drug: placebo
Sponsor:   Daiichi Sankyo Co., Ltd.
Recruiting - verified August 2016

Treatment Convenience in Patients Treated With Dabigatran for Stroke Prophylaxis in Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsor:   Bayer
Recruiting - verified August 2016

Medtronic CoreValve Evolut R U.S. Clinical Study (Evolut 34R Addendum)

Condition:   Aortic Valve Stenosis
Intervention:   Device: CoreValve Evolut 34R TAVR system
Sponsor:   Medtronic Cardiovascular
Recruiting - verified August 2016

Anticoagulation Alone Versus Anticoagulation and Aspirin Following Transcatheter Aortic Valve Interventions (1:1)

Condition:   Transcatheter Aortic Valve Replacement
Interventions:   Drug: AVK;   Drug: Aspirin
Sponsors:   Centre Hospitalier Universitaire de Nīmes;   Medtronic
Not yet recruiting - verified August 2016

Tranexamic Acid in Revision Total Joint Arthroplasty

Conditions:   Revision Total Knee Arthroplasty;   Revision Total Hip Arthroplasty;   Acute Blood Loss Anemia
Interventions:   Procedure: Revision Total Knee Arthroplasty (TKA);   Procedure: Revision Total Hip Arthroplasty (THA)
Sponsors:   Rush University Medical Center;   Mayo Clinic
Recruiting - verified August 2016

An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction

Condition:   Cognitive Impairment
Interventions:   Drug: Jianpi Yishen Huatan Granules;   Other: the placebo
Sponsor:   Dongfang Hospital Affiliated to Beijing University of Chinese Medicine
Not yet recruiting - verified August 2016

Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: natalizumab;   Drug: Placebo
Sponsor:   Biogen
Recruiting - verified August 2016

Thoraflex™ Hybrid IDE Study

Conditions:   Aortic Aneurysm;   Aortic Dissection;   Aortic Rupture
Intervention:   Device: Thoraflex™ Hybrid Device
Sponsors:   Terumo CVS;   Vascutek Ltd.
Enrolling by invitation - verified July 2016

Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases

Conditions:   Diabetes Mellitus, Type 2;   Metabolic Syndrome X;   Hypertension;   Cardiovascular Diseases;   Stroke;   Gout
Intervention:   Other: Fructose-containing Sugars
Sponsors:   University of Toronto;   Canadian Institutes of Health Research (CIHR);   The Physicians' Services Incorporated Foundation;   Canadian Diabetes Association (CDA)
Active, not recruiting - verified May 2016

Brainstem Grey Matter and Cerebral Autoregulation in Migraine With Aura.

Condition:   Migraine With Aura
Interventions:   Other: Magnetic resonance imaging;   Other: Transcranial Doppler
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2016

A Clinical Assessment Study in X-Linked Myotubular Myopathy (XLMTM) Subjects

Condition:   X-linked Myotubular Myopathy
Intervention:  
Sponsor:   Audentes Therapeutics
Recruiting - verified August 2016

Cholinergic Receptor Imaging in Dystonia

Conditions:   Cervical Dystonia;   Dystonia;   Movement Disorder;   Focal Dystonia
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Safety and Efficacy Study of a Protease Activated Receptor-4 Antagonist Being Tested to Reduce the Chances of Having Additional Strokes or "Mini Strokes"

Condition:   Thrombosis
Interventions:   Drug: BMS-986141;   Drug: Aspirin;   Other: Placebo
Sponsor:   Bristol-Myers Squibb
Recruiting - verified July 2016

Cortical Reorganization Models for Motor Areas and Inter-hemispheric Equilibrium Post-stroke: a Pilot Study

Condition:   Stroke
Interventions:   Procedure: Physiotherapy;   Procedure: Occupational therapy;   Procedure: Functional near-infrared spectroscopy
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Completed - verified August 2016

Ticagrelor Versus Clopidogrel in Carotid Artery Stenting

Condition:   Carotid Artery Stenosis
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel;   Drug: Aspirin
Sponsor:   University Hospital, Basel, Switzerland
Not yet recruiting - verified August 2016

A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease

Condition:   Prostate Cancer
Interventions:   Drug: Degarelix;   Drug: Leuprolide
Sponsors:   Ferring Pharmaceuticals;   Memorial Sloan Kettering Cancer Center;   Duke Clinical Research Institute
Recruiting - verified August 2016

Tumor Related Epilepsy

Conditions:   Epilepsy;   Cancer;   Brain Neoplasm
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

A Prospective Cohort Study of Aged People for Chronic Diseases

Conditions:   Aging;   Sarcopenia
Intervention:  
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified August 2016

Study of Urate Elevation in Parkinson's Disease, Phase 3

Condition:   Parkinson's Disease
Interventions:   Drug: Inosine;   Drug: Placebo
Sponsors:   Michael Alan Schwarzschild;   The Parkinson Study Group;   Michael J. Fox Foundation for Parkinson's Research;   University of Rochester;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Non-vitamin K Antagonist Oral Anticoagulants in Patients With Atrial High Rate Episodes

Condition:   Atrial High Rate Episodes
Interventions:   Drug: Edoxaban;   Drug: ASA
Sponsors:   German Atrial Fibrillation Network;   Daiichi Sankyo Europe, GmbH;   Deutsches Zentrum für Herz-Kreislauf-Forschung
Not yet recruiting - verified August 2016

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

Insulin Glargine Versus Regular Insulin Based Regimens in Glycemic Control After Acute Stroke

Conditions:   Acute Stroke;   Hyperglycemia
Interventions:   Drug: Insulin Glargine;   Drug: Regular Insulin
Sponsors:   National Taiwan University Hospital;   Chang Gung Memorial Hospital;   Taipei Medical University Shuang Ho Hospital
Recruiting - verified August 2016

A Feasibility Study to Evaluate the Safety and Effectiveness of Implantation of Flowise Cerebral Flow Diverter (Flowise)

Condition:   Intracranial Aneurysm
Intervention:   Device: Flowise Cerebral Flow Diverter
Sponsor:   Yonsei University
Recruiting - verified August 2016

Study of the Performance of Stroke Management in the Rhône Area

Condition:   Stroke
Intervention:  
Sponsor:   Hospices Civils de Lyon
Recruiting - verified August 2016

Nesiritide in Uncontrolled Hypertension

Condition:   Hypertension
Interventions:   Drug: Nesiritide;   Drug: Placebo
Sponsors:   Oslo University Hospital;   University of Oslo;   University Hospital, Akershus
Recruiting - verified August 2016

Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke

Conditions:   Acute Ischemic Stroke;   Thrombotic Disease
Interventions:   Drug: DS-1040b;   Drug: placebo
Sponsor:   Daiichi Sankyo Inc.
Recruiting - verified August 2016

Observational Study of Hemiplegic Shoulder Pain After Recent Stroke

Conditions:   Shoulder Pain;   Hemiplegia;   Stroke
Interventions:   Other: ShoulderQ which is a shoulder pain questionnaire;   Other: Clinical shoulder examination
Sponsor:   St George's, University of London
Completed - verified August 2016

ImplemeNtation oF demOnstration pRoject for Health systeMs: Atrial Fibrillation (INFORM-AF) Part 1

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Duke University;   Boehringer Ingelheim;   Daiichi Sankyo Inc.
Recruiting - verified August 2016

The Peregrine Post-Market Study for the Treatment of Hypertension

Condition:   Hypertension
Intervention:   Device: Peregrine System Infusion Catheter
Sponsor:   Ablative Solutions, Inc.
Recruiting - verified August 2016

Validation and Standardisation of a Pool of Simplified Evaluation Aimed to the Diagnoses of Aphasic Disorders and Adapted to the Patients Suffering an Acute Phase of Stroke

Condition:   Stroke
Intervention:   Other: BESTA scale
Sponsor:   University Hospital, Limoges
Recruiting - verified June 2016

Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes

Condition:   Transcatheter Aortic Valve Replacement
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Acetylsalicylic acid;   Drug: Clopidogrel
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified August 2016

pCONus Treatment of Wide Neck Intracranial Aneurysms

Condition:   Intracranial Aneurysm
Intervention:   Device: implantation of the pCONus Bifurcation Aneurysm Implant
Sponsor:   Phenox GmbH
Recruiting - verified August 2016

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified August 2016

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified August 2016

Hemodynamic Effect of Lumbosacral Plexus Blockade Versus Spinal Anesthesia

Condition:   Total Hip Replacement
Interventions:   Procedure: Ropivacaine;   Procedure: Bupivacaine
Sponsors:   University of Aarhus;   Aarhus University Hospital;   Regionshospitalet Silkeborg
Recruiting - verified March 2016

GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Type IV Thoracoabdominal Aortic Aneurysms Involving the Visceral Branch Vessels

Condition:   Thoracoabdominal Aortic Aneurysm
Intervention:   Device: GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis
Sponsor:   W.L.Gore & Associates
Active, not recruiting - verified August 2016

aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Device: LARIAT + PVI;   Device: Pulmonary Vein Isolation
Sponsor:   SentreHEART, Inc.
Recruiting - verified August 2016

Phase IV O2 Consumption Study in COPD Patients

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: Budesonide 160 mcg and formoterol fumarate dehydrate 4.5 mcg Inhalation aerosol;   Drug: Matching Placebo pMDI 160/4.5 μg
Sponsor:   AstraZeneca
Completed - verified August 2016

Fluid Responsiveness Evaluation by AbdomiNal Compression in Kids Based on the STARLING Concept

Condition:   Circulatory Failure
Intervention:   Other: Observational study. No special intervention will be made
Sponsor:   Hopital Louis Pradel
Recruiting - verified August 2016

Southwest Health Extension Partnership to Enhance Research Dissemination

Condition:   Cardiovascular Diseases
Interventions:   Other: Enhanced practice transformation support;   Other: Standard practice transformation support
Sponsors:   University of Colorado, Denver;   University of New Mexico
Recruiting - verified August 2016

Prevention of Syncope Trial 6 - Atomoxetine in Vasovagal Syncope

Condition:   Vasovagal Syncope
Interventions:   Drug: Atomoxetine;   Drug: Placebo
Sponsors:   University of Calgary;   Cardiac Arrhythmia Network of Canada
Recruiting - verified August 2016

The Use of Aging Biomarkers to Predict Adverse Outcomes After Cardiac Surgery

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   HealthSpan Dx;   Duke University
Recruiting - verified August 2016

A Predictive Score for the Ischemic Etiology of a Transient Visual Disturbances (VASCO)

Condition:   Vision Disorders
Intervention:   Other: Clinical, ophthalmological and neurological evaluation
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified August 2016

Coronary InterventionS in HIgh-Risk PatiEnts Using a Novel Percutaneous Left Ventricular Support Device (SHIELD II)

Condition:   Coronary Artery Disease
Interventions:   Device: HeartMate PHP;   Device: Abiomed Impella® Recover® LP 2.5
Sponsors:   Thoratec Corporation;   St. Jude Medical
Recruiting - verified August 2016

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion
Recruiting - verified June 2016

Safety of Transcranial Direct Current Stimulation in the Subacute Phase After Stroke

Condition:   Stroke
Interventions:   Device: Active tDCS;   Other: Physical Therapy;   Device: Sham tDCS
Sponsor:   Hospital Israelita Albert Einstein
Recruiting - verified August 2016

Safety of Autologous Human Umbilical Cord Blood Treatment for Perinatal Arterial Ischemic Stroke

Condition:   Perinatal Arterial Ischemic Stroke
Intervention:   Biological: Autologous Cord Blood Infusion
Sponsors:   Florida Hospital;   Cord Blood Registry, Inc.
Suspended - verified August 2016

6-month Intracoronary Optical Coherence Tomography (OCT) Evaluation of Three New Generation Drug Eluting Stent

Condition:   Recurrent Angina After Coronary Stent Placement
Intervention:   Device: optical coherence tomography at 6 months
Sponsor:   Azienda Ospedaliero-Universitaria Careggi
Completed - verified August 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2016

CRIC-Visceral Adiposity and Physical Fitness in Chronic Kidney Disease

Conditions:   Renal Insufficiency, Chronic;   Obesity
Intervention:  
Sponsors:   Baylor College of Medicine;   University of Pennsylvania;   Case Western Reserve University;   University of Michigan;   University of Illinois at Chicago;   University of Maryland;   MetroHealth Medical Center;   The Cleveland Clinic
Recruiting - verified August 2016

Multimodal MRI Study of Ischemic Stroke

Condition:   STROKE
Intervention:   Device: MULTIMODAL MRI
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified August 2016

Longitudinal Study of Intra-Uterine Growth Restriction

Conditions:   IUGR;   Pregnancy
Interventions:   Radiation: Ultrasound;   Radiation: MRI;   Procedure: Blood collection;   Behavioral: Neurological Function Assessment;   Procedure: Placental Analysis;   Procedure: Measurement of body fat
Sponsors:   University of Colorado, Denver;   The Perelman Family Foundation
Recruiting - verified August 2016

Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization

Condition:   Cervical Intraepithelial Neoplasia
Interventions:   Drug: Bupivacaine;   Drug: Adrenaline
Sponsor:   Helse Fonna
Completed - verified August 2016

Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism (RESCUE)-Japan RCT

Condition:   Ischemic Stroke
Interventions:   Procedure: Rescue endovascular therapy;   Procedure: No endovascular therapy
Sponsor:   Shinichi Yoshimura
Terminated - verified August 2016

Evaluation of Myocardial Viability : Dual Energy Cardiac CT vs. Cardiac MRI

Condition:   Myocardial Infarction
Intervention:   Radiation: second propeller arm scanner
Sponsor:   University Hospital, Rouen
Recruiting - verified August 2016

A Proof of Principal Study of Atomoxetine for the Prevention of Vasovagal Syncope

Condition:   Syncope, Vasovagal
Interventions:   Drug: Atomoxetine;   Drug: Matching Placebo
Sponsor:   University of Calgary
Recruiting - verified August 2016

TMS Electrochemotherapy for Glioblastoma Multiforme

Condition:   Glioblastoma
Intervention:   Device: TMS
Sponsor:   University of Aarhus
Suspended - verified October 2014

Plasma Modifications Associated With Rivaroxaban® Treatment for Stroke Prevention

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Completed - verified August 2016

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability

Conditions:   Chronic Troublesome Sialorrhea;   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Intellectual Disability
Interventions:   Drug: IncobotulinumtoxinA;   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified August 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified August 2016

Decompressive Hemicraniectomy in Intracerebral Hemorrhage

Condition:   Cerebral Hemorrhage
Interventions:   Procedure: Decompressive craniectomy (DC) and best medical treatment;   Procedure: Best medical treatment
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified August 2016

Evaluating Anodal tDCS Preceding Aphasia Therapy

Conditions:   Stroke;   Aphasia
Intervention:   Device: transcranial direct current stimulation
Sponsor:   Northwell Health
Recruiting - verified August 2016

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

EndoVascular Treatment With Stent-retriever and/or Thromboaspiration vs. Best Medical Therapy in Acute Ischemic Stroke

Conditions:   Stroke;   Ischemic Stroke
Interventions:   Procedure: Thrombectomy;   Device: Stentriever Solitaire or Penumbra System
Sponsors:   Hospital de Clinicas de Porto Alegre;   Ministry of Health, Brazil;   Medtronic;   Penumbra Inc.;   iSchemaView, Inc;   BrainSonix Inc.
Not yet recruiting - verified August 2016

Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients

Conditions:   Stroke;   Motor Function
Interventions:   Device: Active Repetitive Transcranial Magnetic Stimulation (rTMS);   Drug: Fluoxetine;   Device: Sham repetitive transcranial magnetic stimulation (rTMS);   Drug: Placebo Fluoxetine
Sponsor:   Spaulding Rehabilitation Hospital
Recruiting - verified April 2016

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified August 2016

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Placebo
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified August 2016

Apixaban During Atrial Fibrillation Catheter Ablation: Comparison to Vitamin K Antagonist Therapy

Condition:   Atrial Fibrillation
Interventions:   Drug: Vitamin K antagonist;   Drug: Apixaban
Sponsors:   German Atrial Fibrillation Network;   Bristol-Myers Squibb;   Pfizer;   Deutsches Zentrum für Herz-Kreislauf-Forschung
Recruiting - verified August 2016

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

Early Post-marketing Study of Eliquis (Apixaban)

Condition:   Non-valvular Atrial Fibrillation (NVAF)
Intervention:   Drug: Apixaban
Sponsor:   Bristol-Myers Squibb
Withdrawn - verified August 2016

Patient-centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research

Conditions:   Stroke;   Ischemic Stroke
Intervention:  
Sponsors:   Duke University;   Patient-Centered Outcomes Research Institute;   American Heart Association
Enrolling by invitation - verified August 2016

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Completed - verified June 2016

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

Conditions:   Cardiomyopathy;   Coronary Artery Disease;   Congestive Heart Failure;   Myocardial Infarction
Interventions:   Device: Implantable Cardioverter Defibrillator;   Other: Optimal Medical Therapy
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

Effect of Vorinostat on Nervous System Hemangioblastomas in Von Hippel-Lindau Disease (Missense Mutation Only)

Condition:   Von Hippel-Lindau Disease
Intervention:   Drug: Vorinostat
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified August 2016

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Condition:   Carotid Stenosis
Interventions:   Procedure: Carotid endarterectomy;   Device: Carotid stenting
Sponsors:   Thomas G. Brott, M.D.;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions

Conditions:   Chronic Troublesome Sialorrhea;   Parkinson's Disease;   Post-stroke;   Traumatic Brain Injury
Interventions:   Drug: IncobotulinumtoxinA (100 Units);   Drug: IncobotulinumtoxinA (75 Units);   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Active, not recruiting - verified August 2016

Sequential Expansion of Comparative Effectiveness of Anticoagulants

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

Investigation of the Use of Acupuncture for the Treatment of Spasticity in Chronic Stroke Participants

Condition:   Stroke
Interventions:   Other: Acupuncture;   Other: Sham needle
Sponsor:   Hamilton Health Sciences Corporation
Recruiting - verified August 2016

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified August 2016

Understanding the Exercise-Hypertension Paradox

Condition:   Hypertension
Interventions:   Dietary Supplement: Oral Antioxidant;   Other: Exercise rehabilitation
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography

Conditions:   Atherosclerosis;   Stroke;   Transient Ischemic Attack;   Chronic Stable Angina;   Acute Coronary Syndrome
Intervention:  
Sponsor:   University of Cambridge
Completed - verified August 2016

Dynamic Preload Indicators in Sitting Position

Condition:   Neurosurgery in Sitting Position
Intervention:   Procedure: Sitting position (neurosurgery)
Sponsor:   Hospices Civils de Lyon
Recruiting - verified August 2016

Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia

Conditions:   Oropharyngeal Dysphagia;   Deglutition Disorders
Intervention:   Device: Urostim I stimulation
Sponsor:   University Hospital, Rouen
Terminated - verified August 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified August 2016

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Completed - verified August 2016

Variation of Aortic Compliance Related to Exercise Training With or Without Supervised Sessions

Condition:   Cardiovascular Disease
Intervention:   Procedure: Exercise training with supervised sessions
Sponsor:   University Hospital Center of Martinique
Recruiting - verified August 2016

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified August 2016

Electrical Impedance Myography: Exploratory Studies in Healthy People and People With Neuromuscular Disorders

Conditions:   Neuromuscular Disease;   Motor Neuron Disease;   Inherited Neuromuscular Conditions;   Inherited Neuropathies
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified August 2016

GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)

Condition:   Amyotrophic Lateral Sclerosis
Interventions:   Drug: GM604;   Drug: Placebo comparator
Sponsors:   Genervon Biopharmaceuticals, LLC;   Columbia University;   Massachusetts General Hospital
Completed - verified August 2016

Phase 2A Study of GM 608 in Mild to Moderate Parkinson Disease

Condition:   Parkinson's Disease
Interventions:   Drug: GM608;   Drug: Placebo Comparator
Sponsors:   Genervon Biopharmaceuticals, LLC;   Columbia University
Completed - verified August 2016

Mindful Hearts Study

Conditions:   Cardiovascular Disease;   Psychological Stress;   Stroke;   Coronary Artery Disease
Interventions:   Behavioral: Mindfulness Based Stress Reduction;   Behavioral: Health Education Program
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified August 2016

AMPLATZER Cardiac Plug (ACP) Registry-Long Term Follow-up Protocol

Conditions:   Atrial Fibrillation;   Left Atrial Appendage;   Stroke
Intervention:   Device: Amplatzer Cardiac Plug
Sponsor:   St. Jude Medical
Completed - verified August 2016

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa (Dabigatran etexilate mesilate)
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified August 2016

Intracranial Hypertension and Optic Nerve Sheath Diameter

Conditions:   Cerebral Stroke;   Cerebral Venous Thrombosis
Intervention:   Other: ONSD ultrasound
Sponsor:   Hospices Civils de Lyon
Recruiting - verified August 2016

Balance Rehabilitation With Sensory Recalibration After Stroke

Condition:   Left-sided Hemiplegia Affecting Dominant Side as Late Effect of Cerebrovascular Accident
Interventions:   Other: Cervical vibration;   Other: Prism adaptation;   Other: Conventional rehabilitation
Sponsor:   Rennes University Hospital
Recruiting - verified August 2016

Determination of CRIM Status and Longitudinal Follow-up of Individuals With Pompe Disease

Condition:   Pompe Disease
Intervention:   Other: Observational
Sponsors:   Duke University;   Rare Diseases Clinical Research Network;   National Center for Advancing Translational Science (NCATS);   National Institute of Neurological Disorders and Stroke (NINDS);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified August 2016

Predicting Volume Response Study

Conditions:   Shock;   Hypovolemia
Intervention:   Procedure: Passive Leg Raise (PLR)
Sponsors:   University of Pennsylvania;   Medtronic - MITG
Completed - verified July 2012

Neuropsychological Testing in Patients Undergoing Transvascular Aortic Valve Implantation

Condition:   Aortic Stenosis
Intervention:   Other: Neuropsychological testing
Sponsor:   Hadassah Medical Organization
Withdrawn - verified August 2016

Improving Anticoagulation Control in VISN 1

Conditions:   Anticoagulants;   Atrial Fibrillation;   Venous Thromboembolism
Intervention:   Behavioral: Outreach, Education, and Motivational Interviewing
Sponsor:   VA Office of Research and Development
Active, not recruiting - verified August 2016

AAV2-GDNF for Advanced Parkinson s Disease

Condition:   Parkinson's Disease
Intervention:   Genetic: Convection enhanced delivery/AAV2-GDNF
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Carvedilol for Prevention of Paroxysmal Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Drug: Carvedilol;   Drug: Metoprolol
Sponsors:   University of Calgary;   Heart and Stroke Foundation of Canada;   Libin Cardiovascular Institute of Alberta
Recruiting - verified August 2016

RESCUE Stroke Caregiver Website to Enhance Discharge Planning

Conditions:   Depression;   Quality of Life;   Self Efficacy;   Recovery of Function;   Stress;   Positive Aspects of Caregiving
Interventions:   Behavioral: Caregiver problem-solving;   Other: Standard Care
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

Neuroimmunology Branch Repository

Conditions:   HTLV-1 Infection;   Multiple Sclerosis;   Neurologic Disorders
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified August 2016

Xarelto [SPAF] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban(Xarelto, BAY59-7939)
Sponsor:   Bayer
Active, not recruiting - verified August 2016

Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome

Conditions:   Klinefelter Syndrome;   XXY Syndrome
Interventions:   Drug: Testosterone gel 1%;   Drug: Placebo gel
Sponsors:   University of Colorado, Denver;   Colorado Clinical & Translational Sciences Institute;   Children's Hospital Colorado;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

The Effects of Chronic Exposure to Low-Level Blasts

Condition:   Tramatic Brain Injury
Intervention:  
Sponsors:   National Institute of Neurological Disorders and Stroke (NINDS);   Walter Reed Army Institute of Research (WRAIR);   Naval Medical Research Center
Recruiting - verified August 2016

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Completed - verified August 2016

Effects of Hormone Stimulation on Brain Scans for Cushing s Disease

Condition:   Pituitary Neoplasm
Intervention:   Drug: Acthrel
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders

Conditions:   Amyotrophic Lateral Sclerosis;   Frontotemporal Dementia;   PLS;   Motor Neuron Disease;   Lou Gehrigs Disease;   Familial Disease;   Amyotrophic Lateral Sclerosis, Sporadic;   Muscular Dystrophy;   Miyoshi Myopathy
Intervention:  
Sponsors:   University of Massachusetts, Worcester;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Wii Fit Balance Training Compared to Traditional Balance Training in Patients With SCI/TBI/CVA

Condition:   Distorted; Balance
Interventions:   Procedure: Nintendo Wii Fit;   Procedure: Traditional balance training
Sponsor:   University of Missouri-Columbia
Terminated - verified August 2016

The PERFusion Use in Stroke Evaluation Study

Condition:   Ischemic Stroke
Intervention:   Other: Computed tomography perfusion imaging
Sponsors:   California Pacific Medical Center Research Institute;   California Pacific Medical Center
Recruiting - verified August 2016

Surgery as a Treatment for Medically Intractable Epilepsy

Conditions:   Epilepsy;   Epilepsy, Temporal Lobe;   Partial Epilepsy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

National Epidemiologic Survey on Alcohol and Related Conditions-III

Condition:   Alcohol-Related Disorders
Intervention:  
Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Completed - verified August 2016

Robot-Assisted Hand Motor Therapy for Subjects With Hemiparetic Stroke

Condition:   Stroke
Intervention:   Device: Hand & Wrist Assisting Robotic Device
Sponsor:   University of California, Irvine
Completed - verified August 2016

Efficacy and Safety Study of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within 18 Hours

Condition:   Stroke
Interventions:   Drug: GM602;   Drug: Placebo Comparator
Sponsors:   Genervon Biopharmaceuticals, LLC;   University of California, Los Angeles;   Huntington Hospital;   Hoag Memorial Hospital Presbyterian;   Columbia University;   California Pacific Medical Center Research Institute;   University Hospital Erlangen;   Sarasota Memorial Hospital;   University of Louisville
Recruiting - verified August 2016

Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results - A Long Term Evaluation

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: liraglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Completed - verified August 2016

Post Stroke Psychological Distress

Condition:   Stroke
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   German Federal Ministry of Education and Research
Recruiting - verified August 2016

A Prospective Natural History Study of Patients With Syringomyelia

Conditions:   Syringomyelia;   Arnold Chiari Deformity
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Investigating Mechanism of Action of DAC HYP in the Treatment of High-Inflammatory Multiple Sclerosis (MS)

Conditions:   Multiple Sclerosis;   Multiple Sclerosis, Relapsing-Remitting
Intervention:   Biological: DAC-HYP
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified August 2016

Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Comorbidities

Condition:   Cardiovascular Disease
Interventions:   Drug: Febuxostat;   Drug: Allopurinol
Sponsors:   Takeda;   Teijin America, Inc.
Active, not recruiting - verified August 2016

SISTERS: Spasticity In Stroke Study - Randomized Study

Condition:   Severe Spasticity
Intervention:   Drug: intrathecal baclofen
Sponsor:   Medtronic International Trading Sarl
Active, not recruiting - verified February 2016

CANVAS - CANagliflozin cardioVascular Assessment Study

Conditions:   Diabetes Mellitus, Type 2;   Cardiovascular Diseases;   Risk Factors
Interventions:   Drug: Canagliflozin (JNJ-28431754);   Drug: Placebo
Sponsors:   Janssen Research & Development, LLC;   The George Institute for Global Health, Australia
Active, not recruiting - verified August 2016

Physiological Investigations of Movement Disorders

Conditions:   Parkinson's Disease;   Tourette's Syndrome;   Tic Disorders;   Dystonia;   Movement Disorders
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Suspended - verified August 2016

Stress Testing and Cardiac Magnetic Resonance

Condition:   Coronary Disease
Intervention:   Drug: regadenoson
Sponsors:   University of Chicago;   Astellas Pharma Inc
Recruiting - verified August 2016

Inhalatorial Sedation in Patient With Subarachnoid Hemorrhage (SAH) Versus Conventional Intravenous Sedation

Conditions:   Stroke;   Subarachnoid Hemorrhage
Interventions:   Drug: Propofol;   Drug: Isoflurane
Sponsor:   Azienda Ospedaliera San Gerardo di Monza
Completed - verified November 2011

Can Hypothermia be Incorporated Into Primary Angioplasty for Heart Attack?

Condition:   ST-Elevation Myocardial Infarction
Intervention:   Device: Life Recovery Systems ThermoSuit
Sponsor:   Life Recovery Systems
Not yet recruiting - verified August 2016

Natural History Study of Patients With Neurofibromatosis Type 2

Conditions:   Spinal Cord Disease;   Intracranial Central Nervous System Disorder;   Neurologic Disorders;   Brain Neoplasms
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified August 2016

Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo

Condition:   Epilepsies, Partial
Interventions:   Drug: Lyrica (pregabalin);   Drug: placebo
Sponsor:   Pfizer
Recruiting - verified August 2016

SDCC - Prospective Cohort Study of Chronic Renal Insufficiency

Condition:   Renal Insufficiency, Chronic
Intervention:  
Sponsors:   University of Pennsylvania;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Johns Hopkins University;   Case Western Reserve University;   University of Michigan;   University of Illinois at Chicago;   Tulane University;   Kaiser Permanente
Active, not recruiting - verified August 2016

ESCAPE Migraine Trial

Conditions:   Migraine Disorders;   Heart Septal Defects, Atrial
Interventions:   Device: PFO Closure with Premere investigational device.;   Drug: Medical management/current medications per standard of care by personal physician.
Sponsor:   St. Jude Medical
Terminated - verified August 2016

Evaluation and Treatment of Neurosurgical Disorders

Condition:   Neurologic Disorders
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Evaluation and Treatment of Patients With Epilepsy

Condition:   Epilepsy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016

Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease

Conditions:   Hemangioblastoma;   Hippel Lindau Disease
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified August 2016

Genetic Analysis of the Chiari I Malformation

Conditions:   Syringomyelia;   Type I Arnold Chiari Malformation
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified August 2016