Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Robot Assisted Gait Training in Patients With Infratentorial Stroke

Condition:   Stroke
Interventions:   Other: Robot, then conventional training;   Other: Conventional, then robot training
Sponsor:   National Rehabilitation Center, Seoul, Korea
Recruiting - verified October 2015

A Stepped-wedge Cluster Randomized Controlled Trial for Evaluating an Intervention in Patients With Stroke Tailored Education in Addition to Physiotherapist Treatment

Condition:   Stroke
Intervention:   Other: Multimodal intervention
Sponsor:   University of Malaga
Not yet recruiting - verified November 2015

Impact of Neuromonitoring During Cardiac Procedures

Conditions:   Delirium;   Stroke;   Acute Kidney Injury
Intervention:  
Sponsor:   Medtronic - MITG
Not yet recruiting - verified February 2016

Impact of Anesthesia Type on Outcome in Patients With Acute Ischemic Stroke (AIS) Undergoing Endovascular Treatment

Condition:   Acute Stroke
Interventions:   Other: Intravenous anesthetics;   Other: local anesthesia;   Other: Controlled ventilation;   Other: Spontaneous breathing
Sponsor:   Beijing Tiantan Hospital
Not yet recruiting - verified February 2016

Physical Activity Maintenance in Stroke

Condition:   Stroke
Interventions:   Behavioral: Brochure and Telephone Support;   Behavioral: Brochure
Sponsor:   McMaster University
Not yet recruiting - verified February 2016

The Relationship Between Clotting Factor VIII and Bleeding Adverse Reactions in Patients Under the Therapies of Thrombolysis, Anticoagulation and Anti-platelet

Conditions:   Bleeding;   Ischemic Stroke
Intervention:  
Sponsors:   Zhujiang Hospital;   Guangdong Province, Department of Science and Technology
Not yet recruiting - verified October 2015

Chronicity Dependence of a Balance Training in Adults Post-stroke

Condition:   Stroke, Postural Balance, Virtual Rehabilitation
Intervention:   Other: balance virtual rehabilitation
Sponsors:   Hospitales Nisa;   Universidad Politécnica de Valencia
Completed - verified February 2016

Reconstruction of Pathological Changes of the Ophthalmic Artery in Patients With Retinal Artery Occlusion

Condition:   Retinal Artery Occlusion
Intervention:   Other: MRI of the cerebral arteries
Sponsor:   Vienna Institute for Research in Ocular Surgery
Recruiting - verified February 2016

Safety and Efficacy Study of a Protease Activated Receptor-4 Antagonist Being Tested to Reduce the Chances of Having Additional Strokes or "Mini Strokes"

Condition:   Thrombosis
Interventions:   Drug: BMS-986141;   Drug: Aspirin;   Other: Placebo
Sponsor:   Bristol-Myers Squibb
Not yet recruiting - verified January 2016

Atrial Fibrillation Registry in Jordan

Condition:   Atrial Fibrillation
Intervention:   Other: Observing medications prescribed per physicians discretion
Sponsor:   Jordan Collaborating Cardiology Group
Not yet recruiting - verified February 2016

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Conditions:   Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified February 2016

Feasibility and Effectiveness Study of Implementing Prism Adaptation as a Treatment for Spatial Neglect After Stroke

Conditions:   Sensory Neglect;   Stroke
Interventions:   Behavioral: Prism Goggles;   Other: Non-Shifting Goggles
Sponsor:   Nova Scotia Health Authority
Not yet recruiting - verified February 2016

Effects of Transcranial Direct Current Stimulation Plus Language Therapy for Naming in Subacute Left Hemisphere Stroke

Condition:   Stroke
Interventions:   Device: A-tDCS (1 mA);   Behavioral: SALT;   Device: Sham
Sponsors:   Johns Hopkins University;   University of South Carolina
Not yet recruiting - verified January 2016

Which Parameters of Short-term Blood Pressure Variability Best Predict Early Outcomes in Acute Ischemic Stroke

Condition:   Stroke
Intervention:  
Sponsor:   Dongguan People's Hospital
Recruiting - verified February 2016

European Registry on the ACE Reperfusion Catheters and the Penumbra System in the Treatment of Acute Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:   Device: Penumbra Aspiration System
Sponsor:   Penumbra Inc.
Not yet recruiting - verified February 2016

Sensory Stimulation to Enhance Hand Function Post Stroke

Condition:   Stroke
Interventions:   Other: Vibration;   Other: Placebo (for vibration);   Behavioral: therapy
Sponsors:   Medical University of South Carolina;   National Institute of General Medical Sciences (NIGMS)
Recruiting - verified February 2016

Energy Consumption and Cardiorespiratory Load During Walking With and Without Robot-Assistance

Condition:   Stroke
Interventions:   Device: Lokomat;   Other: Treadmill;   Other: Overground
Sponsor:   Vrije Universiteit Brussel
Recruiting - verified February 2016

Quality Improvement and Practice Based Research in Neurology Using the EMR

Conditions:   Brain Tumors;   Epilepsy;   Migraine;   Mild Cognitive Impairment;   Concussion;   Multiple Sclerosis;   Neuropathy;   Parkinson's;   Restless Legs Syndrome;   Stroke
Intervention:   Drug: Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field; see Intervention Description)
Sponsor:   NorthShore University HealthSystem Research Institute
Not yet recruiting - verified January 2016

Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients With InteRmediate Stenosis

Condition:   Stable Angina
Intervention:   Device: Drug-eluting stent
Sponsors:   Seoul National University Hospital;   Ajou University School of Medicine;   Keimyung University Dongsan Medical Center;   Inje University
Not yet recruiting - verified February 2016

Early Intensive Physical Therapy in Subarachnoid Hemorrhage

Condition:   Subarachnoid Hemorrhage
Intervention:   Other: Physical Therapy
Sponsor:   University of Colorado, Denver
Not yet recruiting - verified February 2016

Cortical Reorganization Models for Motor Areas and Inter-hemispheric Equilibrium Post-stroke: a Pilot Study

Condition:   Stroke
Interventions:   Procedure: Physiotherapy;   Procedure: Occupational therapy;   Procedure: Functional near-infrared spectroscopy
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified February 2016

The Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis

Condition:   Aortic Stenosis
Interventions:   Procedure: Surgical aortic valve replacement (SAVR);   Device: Transcatheter Aortic Valve Replacement (TAVR)
Sponsor:   Edwards Lifesciences
Not yet recruiting - verified February 2016

Ticagrelor Versus Clopidogrel in Carotid Artery Stenting

Condition:   Carotid Artery Stenosis
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel;   Drug: Aspirin
Sponsor:   University Hospital, Basel, Switzerland
Not yet recruiting - verified February 2016

Preload Dependency Evaluation With Stroke Volume Variation During Alveolar Recruitment Manoeuvres

Conditions:   Coronary Artery Disease;   Coronary Artery Bypass;   Hypovolemia;   Anesthesia, General;   Pulmonary Atelectasis
Interventions:   Other: tee measurement;   Other: flotrac measurement;   Other: clearsight measurement
Sponsor:   University Hospital, Clermont-Ferrand
Not yet recruiting - verified February 2016

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage

Condition:   Aortic Valve Disorder
Interventions:   Device: Lotus Heart valve system;   Device: WATCHMAN
Sponsor:   University Hospital Inselspital, Berne
Not yet recruiting - verified February 2016

Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain

Conditions:   Vertebral Artery Dissection;   Cerebrovascular Accident;   Stroke
Intervention:   Other: Head positions and spinal manipulation
Sponsors:   Canadian Memorial Chiropractic College;   National Chiropractic Mutual Insurance Company (NCMIC)
Not yet recruiting - verified February 2016

Ferumoxytol-enhanced Imaging and Mapping in neuroAIDS

Condition:   AIDS Dementia Complex
Intervention:   Drug: Ferumoxytol
Sponsors:   Beau Nakamoto;   Hawaii Pacific Health;   University of Hawaii;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2016

Regional and Long Term Outcomes of Acute Kidney Injury in England From 2000 to 2015 - A National Database Study

Condition:   Acute Kidney Injury
Intervention:  
Sponsor:   Derby Hospitals NHS Foundation Trust
Completed - verified February 2016

Low Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa

Conditions:   Sickle Cell Disease;   Sickle Cell Anemia;   Stroke
Interventions:   Drug: Moderate Dose Hydroxyurea;   Drug: Low Dose Hydroxyurea
Sponsors:   Vanderbilt University;   Aminu Kano Teaching Hospital;   Murtala Muhammed Specialist Hospital
Not yet recruiting - verified February 2016

Evaluation of the Roadsaver Stent Used in Conjunction With the Nanoparasol Embolic Protection System for Carotid Artery Stenosis

Condition:   Carotid Artery Stenosis
Interventions:   Device: Roadsaver™ Carotid Artery Stent Device;   Device: Nanoparasol® Embolic Protection System
Sponsor:   Microvention-Terumo, Inc.
Not yet recruiting - verified February 2016

Walking Meditation Exercise in Breast Cancer Patients

Condition:   Breast Cancer
Intervention:   Other: Exercise
Sponsor:   Chulalongkorn University
Enrolling by invitation - verified February 2016

Knowledge Translation for Patients With Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Intervention:   Behavioral: knowledge translation
Sponsors:   Montreal General Hospital;   Sanofi;   Canadian Institutes of Health Research (CIHR);   Fonds de la Recherche en Santé du Québec
Completed - verified January 2016

Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations

Conditions:   Frontotemporal Lobar Degeneration;   FTLD;   Frontotemporal Dementia;   FTD;   Tauopathies
Intervention:   Drug: 18F-AV-1451
Sponsors:   Columbia University;   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified February 2016

APIXABAN in the Prevention of Stroke and Systemic Embolism in Patients With Atrial Fibrillation in Real-Life Setting in France SNIIRAM Study

Condition:   Anticoagulation
Interventions:   Drug: VKA;   Drug: Apixaban;   Drug: dabigatran;   Drug: rivaroxaban
Sponsor:   Bristol-Myers Squibb
Active, not recruiting - verified January 2016

Metabolic Effects of Angiotensin-(1-7)

Conditions:   Obesity;   Insulin Resistance;   Hypertension;   Metabolic Cardiovascular Syndrome
Interventions:   Drug: Angiotensin-(1-7);   Drug: Saline
Sponsor:   Vanderbilt University
Recruiting - verified February 2016

CONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG

Conditions:   Acute Brain Injuries;   Consciousness Disorders
Intervention:  
Sponsors:   Rigshospitalet, Denmark;   University of Copenhagen
Not yet recruiting - verified February 2016

Hydroxychloroquine in Acute Coronary Syndrome: Prevention of Recurrent Cardiovascular Events (OXI)

Conditions:   Myocardial Infarction;   Acute Coronary Syndrome;   Inflammation;   Hydroxychloroquine;   Antirheumatic Agents;   Cardiovascular Diseases;   Angina, Unstable
Interventions:   Drug: Hydroxychloroquine;   Drug: Placebo
Sponsors:   Helsinki University Central Hospital;   Finnish Foundation for Cardiovascular Research;   Orion Corporation, Orion Pharma
Recruiting - verified February 2016

GLP-1 and Hyperoxia for Organ Protection in Heart Surgery

Conditions:   Coronary Disease;   Shock, Cardiogenic;   Renal Failure;   Stroke;   Brain Injury;   Aortic Valve Disease
Interventions:   Drug: Byetta (Lilly, Exenatide);   Drug: Conoxia (AGA, oxygen);   Drug: 20% Human Albumin
Sponsor:   Rigshospitalet, Denmark
Recruiting - verified February 2016

Consolidating Tools for Outcomes in Resuscitation

Conditions:   Cardiac Arrest;   Cardiopulmonary Resuscitation;   Simulation;   Education
Interventions:   Device: Knowledge-based cognitive aid;   Device: Cognitive aids with roles defined (CARD);   Device: Integrated cognitive aids
Sponsors:   Ottawa Hospital Research Institute;   The Physicians' Services Incorporated Foundation;   University of Ottawa;   Children's Hospital of Eastern Ontario;   The Hospital for Sick Children;   Montreal Children's Hospital of the MUHC;   Alberta Children's Hospital;   Stollery Children's Hospital
Not yet recruiting - verified February 2016

Testing a Community Intervention to Increase Aspirin Use

Conditions:   Myocardial Infarction;   Stroke
Interventions:   Other: Mass Media plus clinic intervention.;   Other: Media
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified February 2016

Communicating Multiple Disease Risks

Condition:   Healthy
Interventions:   Behavioral: Cognitive interview;   Other: Survey
Sponsor:   Washington University School of Medicine
Recruiting - verified February 2016

Patient Convenience Study

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

Reliability of the Melbourne Assessment

Conditions:   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Meningomyelocele;   Central Nervous System Diseases
Intervention:  
Sponsor:   University Children's Hospital, Zurich
Recruiting - verified September 2015

Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults

Condition:   Sialorrhea
Intervention:   Drug: MYOBLOC
Sponsor:   US WorldMeds LLC
Recruiting - verified January 2016

Randomized Trial of COBRA PzF Stenting to Reduce Duration of Triple Therapy

Conditions:   Angina, Stable;   Angina, Unstable;   Anticoagulants
Interventions:   Device: COBRA PzF;   Device: DES
Sponsor:   CeloNova BioSciences, Inc.
Recruiting - verified February 2016

Burden of Illness in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Standard of care in AF in Denmark
Sponsor:   Bayer
Completed - verified February 2016

The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment

Conditions:   Homocysteine;   Coronary Disease;   Angioplasty,Balloon,Coronary;   Contrast Media;   Nephropathy;   Hypertension
Interventions:   Drug: Enalapril Maleate Tablets(as the program-based antihypertension);   Drug: Enalapril Maleate and Folic Acid tablets(as the program-based antihypertension);   Drug: Placebo
Sponsor:   Fuling Central Hospital of Chongqing City
Recruiting - verified February 2016

Effects of Mental Practice for Mobility in Post-stroke Hemiparesis

Conditions:   Stroke;   Hemiparesis
Interventions:   Other: Mental practice;   Other: Cognitive training and Relaxation
Sponsor:   Federal University of Juiz de Fora
Recruiting - verified February 2016

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

Conditions:   Secondary Prevention;   Stroke;   Ischemic Heart Disease;   Coronary Heart Disease
Interventions:   Drug: Acetylsalicylic Acid (Asprin, BAYE4465);   Drug: Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
Sponsor:   Bayer
Recruiting - verified February 2016

HT-3951 vs. Placebo in Stroke Rehabilitation

Condition:   Ischemic Stroke
Interventions:   Drug: HT-3951;   Drug: Placebo
Sponsor:   Dart NeuroScience, LLC
Recruiting - verified February 2016

Novel Treatment For Pusher Syndrome Using Physical Therapy

Condition:   Pusher Syndrome
Interventions:   Other: Novel physical therapy;   Other: Standard physical therapy
Sponsor:   Loma Linda University
Enrolling by invitation - verified January 2016

Optilene® Suture for Coronary Artery Bypass Graft Surgery

Conditions:   Coronary Heart Disease;   Multi Vessel Coronary Artery Disease
Intervention:   Procedure: Coronary Artery Bypass Graft surgery
Sponsors:   Aesculap AG;   B.Braun Surgical SA
Recruiting - verified January 2016

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified February 2016

ALLiance for sEcondary PREvention After an Episode of Acute Coronary Syndrome (ALLEPRE)

Condition:   Acute Coronary Syndrome
Interventions:   Behavioral: Nurse-led Intensive Secondary Prevention Programme;   Behavioral: Usual Treatment
Sponsor:   Azienda Ospedaliero-Universitaria di Parma
Recruiting - verified February 2016

Interactive Exoskeleton Robot for Walking - Knee Joint

Condition:   Stroke
Intervention:   Device: Knee robot
Sponsors:   Chinese University of Hong Kong;   The Hong Kong Polytechnic University
Recruiting - verified February 2016

Clinical Performance and Safety Assessment of the Paladin®

Condition:   Carotid Artery Stenosis
Intervention:   Device: Paladin® Embolic Protection System
Sponsor:   Contego Medical, LLC
Recruiting - verified February 2016

Southwest Health Extension Partnership to Enhance Research Dissemination

Condition:   Cardiovascular Diseases
Interventions:   Other: Enhanced practice transformation support;   Other: Standard practice transformation support
Sponsors:   University of Colorado, Denver;   University of New Mexico
Recruiting - verified February 2016

Decision Aids in Cerebral Aneurysm Treatment

Condition:   Cerebral Aneurysm
Interventions:   Behavioral: Option grid for cerebral aneurysm treatment;   Behavioral: Control
Sponsor:   Dartmouth-Hitchcock Medical Center
Withdrawn - verified February 2016

The Effects of CPAP Withdrawal on Cerebral Vascular Reactivity and Brain Oxygenation in OSA

Condition:   Sleep Apnea, Obstructive
Intervention:   Device: Continuous positive airway pressure device
Sponsor:   University of Zurich
Recruiting - verified February 2016

High-risk Patients in Cardiac Surgery Procedures: HiriSCORE

Condition:   C.Surgical Procedure; Cardiac
Intervention:  
Sponsors:   University of Sao Paulo General Hospital;   InCor Heart Institute;   Cardiology Institute of the Distrito Federal, Brazil;   Clinical Hospital Samuel Libânio of Pouso Alegre, Brazil;   Beneficência Portuguesa of São Paulo, Brazil;   Hospital Clínico Universitario de Valladolid;   National Institute of Cardiology, Laranjeiras, Brazil;   Russian Cardiology Research and Production Center, Russian;   La Princesa University Hospital Madrid, Spain;   TotalCor Hospital, Brazil;   Royal Adelaide Hospital;   Santa Casa de Misericórdia of Marília, Brazil;   Hospital de Base
Active, not recruiting - verified June 2015

Neutrophil Extracellular Traps and Thrombolysis in the Acute Stroke

Condition:   Acute Stroke
Intervention:   Procedure: Sample of Blood
Sponsors:   Centre Hospitalier St Anne;   Institut National de la Santé Et de la Recherche Médicale, France;   Paris Descartes University
Recruiting - verified February 2016

Acupuncture for Ischemic Post-stroke Depression

Condition:   Post-stroke Depression
Interventions:   Device: acupuncture;   Drug: placebo;   Device: sham-acupoint acupuncture;   Drug: Fluoxetine
Sponsors:   Menghan Li;   State Administration of Traditional Chinese Medicine of the People's Republic of China
Not yet recruiting - verified February 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified February 2016

Interactive Exoskeleton Robot for Walking - Ankle Joint

Condition:   Stroke
Interventions:   Device: Ankle Robot with Power Assistance;   Device: Sham
Sponsors:   Chinese University of Hong Kong;   Innovation and Technology Commission, Hong Kong
Recruiting - verified February 2016

Effects of Training Caregivers on the Outcomes of Stroke Survivors and Caregivers in Zimbabwe

Condition:   Stroke
Intervention:   Other: Caregiver training
Sponsors:   University of Zimbabwe;   National Institutes of Health (NIH)
Recruiting - verified February 2016

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Recruiting - verified February 2016

An Observational Cross-sectional Study Evaluating the Sociodemographic and Clinical Characteristics of Patients Diagnosed With NVAF With a Risk of Stroke or Systemic Embolism, Who Are on Treatment to Adequately Control Their Coagulation and Treated in Primary Care Centres

Conditions:   Stroke;   Prevention and Control;   Atril Fibrillation
Intervention:   Drug: Direct oral anticoagulants
Sponsor:   Bayer
Active, not recruiting - verified February 2016

Left Atrial Appendage Closure With SentreHeart Lariat® Device

Conditions:   Cardioembolic Stroke;   Atrial Fibrillation
Interventions:   Procedure: Left atrial appendage closure;   Device: SentreHeart Lariat®
Sponsor:   Baylor Research Institute
Recruiting - verified February 2016

Quality of Life After Stroke Using a Telemedicine-based Stroke Network

Condition:   Stroke
Intervention:   Drug: Alteplase
Sponsors:   Thomas Jefferson University;   Genentech, Inc.
Recruiting - verified February 2016

Optimizing Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke

Conditions:   Stroke;   Ischemic Stroke
Intervention:   Device: Mechanical Thrombectomy
Sponsors:   The University of Texas Health Science Center, Houston;   Stryker Neurovascular;   WellStar Health System;   Kaiser Permanente;   Florida Hospital;   Emory University;   Riverside Methodist Hospital;   Valley Baptist Medical Center;   St. Louis University;   University of Kansas Medical Center
Recruiting - verified February 2016

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Active, not recruiting - verified February 2016

Fall Prevention and Locomotion Recovery in Post-stroke Patients: A Multimodal Training

Condition:   Stroke
Interventions:   Device: Cycling;   Device: Balance;   Other: Standard physical therapy
Sponsors:   Fondazione Salvatore Maugeri;   Politecnico di Milano
Recruiting - verified February 2016

Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis

Condition:   Aortic Stenosis
Intervention:   Procedure: surgical aortic valve replacement
Sponsor:   Clinical Centre of Serbia
Recruiting - verified February 2016

Rehabilitation Training After Stroke

Condition:   Stroke
Intervention:   Other: Rehabilitation
Sponsors:   NIHR Exeter Clinical Research Facility;   The Stroke Association, United Kingdom;   University of Exeter
Active, not recruiting - verified February 2016

A Dose-escalating Clinical Trial With KH176

Conditions:   MELAS;   LHON;   Leigh Syndrome;   Mitochondrial Disease;   Mitochondrial DNA tRNALeu(UUR) m.3243AInterventions:   Drug: KH176;   Drug: placebo
Sponsors:   Khondrion BV;   Drug Research Unit Ghent, Belgium
Completed - verified February 2016

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified February 2016

Post-Market Clinical Follow-Up Study to Confirm Clinical Performance and Safety of the Codman Enterprise® 2 Vascular Reconstruction Device in the Endovascular Treatment of Intracranial Aneurysms

Condition:   Intracranial Aneurysm
Intervention:   Device: Enterprise 2 Vascular Reconstruction Device
Sponsor:   Codman & Shurtleff
Recruiting - verified February 2016

Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension

Condition:   Hypertension
Intervention:   Drug: Trimethaphan
Sponsor:   Vanderbilt University
Recruiting - verified February 2016

Home-based Respiratory Training After Stroke

Condition:   Stroke
Interventions:   Other: Respiratory training;   Other: Control
Sponsor:   Federal University of Minas Gerais
Recruiting - verified February 2016

Neuroprotection in Patients Undergoing Aortic Valve Replacement

Conditions:   Aortic Stenosis;   Brain Infarction;   Cerebrovascular Accident;   Stroke
Interventions:   Device: Embol-X Embolic Protection Device;   Device: CardioGard Cannula
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 2016

Informal Caregivers ANSWERS

Conditions:   Stroke;   Traumatic Rain Injury
Interventions:   Behavioral: ANSWERS - Acquiring New Skills While Enhancing Remaining Strengths;   Other: Control
Sponsor:   VA Office of Research and Development
Recruiting - verified February 2016

Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage:

Conditions:   Subarachnoid Hemorrhage;   Cerebral Vasospasm;   Hyponatremia
Interventions:   Drug: HTS 3%;   Drug: Standard fluid management
Sponsor:   Thomas Jefferson University
Recruiting - verified February 2016

Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)

Conditions:   FTLD;   Progressive Supranuclear Palsy (PSP);   Frontotemporal Dementia (FTD);   Corticobasal Degeneration (CBD);   PPA Syndrome;   Behavioral Variant Frontotemporal Dementia (bvFTD);   Semantic Variant Primary Progressive Aphasia (svPPA);   Nonfluent Variant Primary Progressive Aphasia (nfvPPA);   FTD With Amyotrophic Lateral Sclerosis (FTD/ALS);   Amyotrophic Lateral Sclerosis (ALS);   Oligosymptomatic PSP (oPSP);   Corticobasal Syndrome (CBS)
Intervention:  
Sponsors:   University of California, San Francisco;   National Center for Advancing Translational Science (NCATS);   National Institute of Neurological Disorders and Stroke (NINDS);   The Bluefield Project;   Tau Consortium
Recruiting - verified February 2016

Uninterrupted Dabigatran Etexilate in Comparison to Uninterrupted Warfarin in Pulmonary Vein Ablation (RE-CIRCUIT)

Condition:   Atrial Fibrillation
Interventions:   Drug: Warfarin;   Drug: Dabigatran Etexilate 150mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

Effects of Home-based vs. Clinic-based Rehabilitation on Sensorimotor, Cognition, Daily Function, and Participation

Condition:   Chronic Stroke
Intervention:   Behavioral: bilateral training with and without mirror feedback
Sponsor:   Chang Gung Memorial Hospital
Recruiting - verified December 2015

Resistive Training Combined With Nutritional Therapy After Stroke

Condition:   Stroke
Interventions:   Other: Protein;   Other: Placebo
Sponsors:   VA Office of Research and Development;   Baltimore VA Medical Center
Recruiting - verified February 2016

Short Message Service (SMS) Reminders for Stroke Secondary Preventative Medications

Conditions:   Stroke;   Ischemic Attack, Transient
Intervention:   Other: SMS reminder
Sponsors:   NHS Greater Glasgow and Clyde;   University of Glasgow
Completed - verified January 2016

Role of PPAR-y Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)

Condition:   Systemic Lupus Erthematosus
Interventions:   Radiation: PET/CT;   Drug: Pioglitazone;   Procedure: Vascular function studies
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified October 2015

Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS)

Condition:   Stroke
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin (Acetylsalicylic acid, BAY1019036);   Other: Rivaroxaban-Placebo;   Other: Aspirin-Placebo
Sponsors:   Bayer;   Janssen, LP;   Hamilton Health Sciences Cooperation, Population Health Research Institute
Recruiting - verified February 2016

Cerebral Embolic Load in Patients Undergoing Surgical Aortic Valve Replacement: A Comparison of the Conventional With the Minimized Extracorporeal Circulation Technique Using Transcranial Doppler Ultrasound

Conditions:   Aortic Valve Stenosis;   Extracorporeal Circulation
Interventions:   Procedure: Minimized Extracorporeal Circulation (MECC);   Procedure: Conventional Extracorporeal Circulation (CECC)
Sponsor:   University Hospital Inselspital, Berne
Active, not recruiting - verified February 2016

Effects of a Self-Management Group-Intervention on Participation in Post-Stroke Patients.

Condition:   Stroke
Interventions:   Behavioral: Self-Management group-intervention;   Behavioral: Standard Care
Sponsors:   Uzi Milman;   University of Haifa
Recruiting - verified February 2016

Hospital Processes Reengineering of Intravenous Thrombolysis in Acute Ischemic Stroke in China

Conditions:   Ischemic Stroke;   Adverse Effect of Thrombolytic Drugs, Sequela
Interventions:   Behavioral: Advance hospital notification by EMS;   Behavioral: stroke team notification;   Behavioral: key performance indicators feedback form;   Behavioral: standard informed consent procedures;   Behavioral: performance of thrombolysis at CT-room
Sponsor:   First Affiliated Hospital of Jinan University
Completed - verified February 2016

Effects of Neuromodulation on Verbal Fluency in Post-stroke Aphasia

Condition:   Post-stroke Aphasia
Intervention:   Device: TNM(trademark) - thermoneuromodulation
Sponsors:   Scion NeuroStim;   Duke University
Active, not recruiting - verified February 2016

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability

Conditions:   Chronic Troublesome Sialorrhea;   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Intellectual Disability
Interventions:   Drug: IncobotulinumtoxinA;   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified January 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity

Condition:   Spasticity
Interventions:   Device: repetitive Transcranial Magnetic Stimulation (rTMS);   Device: Sham repetitive Transcranial Magnetic Stimulation
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Active, not recruiting - verified February 2016

Optimization of Fluid Therapy in Sepsis by a Passive Leg Raising Test

Condition:   Shock, Septic
Interventions:   Procedure: Passive Leg Raising Test;   Procedure: Standard of care
Sponsors:   Karolinska Institutet;   Stockholm County Council, Sweden;   Svenska militärläkarföreningen
Terminated - verified February 2016

Feasibility Controlled Trial of Tibial Nerve Stimulation for Stroke Related Urinary Incontinence

Conditions:   Stroke;   Urinary Incontinence
Interventions:   Device: NeuroTrac continence stimulators;   Device: NeuroTrac continence stimulators
Sponsors:   Glasgow Caledonian University;   The Stroke Association, United Kingdom;   University of Central Lancashire;   Nursing, Midwifery & Allied Health Professions Research Unit;   NHS Greater Glasgow and Clyde;   NHS Lanarkshire
Recruiting - verified February 2016

Human Intervention Study of Egg Protein Derivative on Cardiovascular Risk

Condition:   Hypertension
Intervention:   Dietary Supplement: Egg albumin-derived peptide
Sponsor:   University College Cork
Completed - verified February 2016

Impact of Standardized MONitoring for Detection of Atrial Fibrillation in Ischemic Stroke

Conditions:   Stroke;   Atrial Fibrillation
Interventions:   Other: prolonged ECG monitoring;   Device: ECG
Sponsors:   Charite University, Berlin, Germany;   Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma
Recruiting - verified February 2016

Active Surveillance Research Program for the Assessment of the Safety and the Effectiveness of Linagliptin

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified February 2016

Total Shoulder Arthroplasty Near-infrared Spectroscopy

Condition:   Cerebral Ischemia
Interventions:   Device: Casmed Fore-Sight Elite;   Device: Non-invasive Cardiac Output Monitor (NICOM)
Sponsor:   Hospital for Special Surgery, New York
Completed - verified February 2016

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified February 2016

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis.

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Placebo
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified February 2016

Remote Preconditioning Over Time To Empower Cerebral Tissue

Conditions:   Ischemic Stroke;   Cerebral Small Vessel Disease;   Cognitive Decline
Intervention:   Device: Ischemic Preconditioning
Sponsors:   University of California, Los Angeles;   American Heart Association
Recruiting - verified February 2016

Chest CT With Iterative Reconstruction as an Alternative to Conventional Chest X-ray Prior to Heart Surgery

Conditions:   Cardiac Defects;   Disorder; Heart, Functional, Postoperative, Cardiac Surgery;   Stroke
Intervention:   Other: CT scan
Sponsors:   UMC Utrecht;   ZonMw: The Netherlands Organisation for Health Research and Development
Recruiting - verified February 2016

Evaluation of the ReVive SE Device for Intra-Arterial Thrombectomy in Acute Ischemic Stroke

Condition:   Stroke
Intervention:  
Sponsor:   Codman & Shurtleff
Recruiting - verified February 2016

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

Neural Basis of Decision-Making Deficits in Traumatic Brain Injury

Condition:   Traumatic Brain Injury
Intervention:  
Sponsors:   National Institute of Neurological Disorders and Stroke (NINDS);   Uniformed Services University of the Health Sciences
Recruiting - verified January 2016

Effect of Neuromuscular Electrostimulation on Sympathetic Nerve Activity in Patients With Type 2 Diabetes (ELECTROSYMP2)

Conditions:   Type 2 Diabetes;   Insulin Resistance
Interventions:   Device: effect of neuromuscular electrostimulation (NMES);   Device: effect of neuro electrostimulation (NES);   Other: effect of voluntary contractions (VC)
Sponsor:   University Hospital, Caen
Not yet recruiting - verified January 2016

Vascular Dysfunction in Paediatric IBD

Conditions:   Inflammatory Bowel Disease;   Crohn Disease;   Ulcerative Colitis
Intervention:  
Sponsors:   Great Ormond Street Hospital for Children NHS Foundation Trust;   National Institute for Health Research, United Kingdom
Recruiting - verified February 2016

Trevo and Medical Management Versus Medical Management Alone in Wake Up and Late Presenting Strokes

Condition:   Ischemic Stroke
Interventions:   Device: Trevo Thrombectomy Procedure;   Other: Medical Management
Sponsor:   Stryker Neurovascular
Recruiting - verified February 2016

HEart and BRain Interfaces in Acute Ischemic Stroke

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Center for Stroke Research Berlin
Recruiting - verified January 2016

OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity

Conditions:   Muscle Spasticity;   Stroke
Interventions:   Biological: onabotulinumtoxinA;   Drug: placebo (normal saline)
Sponsor:   Allergan
Terminated - verified January 2016

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Losmapimod 7.5 mg twice daily;   Drug: Placebo twice daily
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Recruiting - verified February 2016

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Recruiting - verified January 2016

Intra-aortic Balloon Counterpulsation in Patients Undergoing Cardiac Surgery

Condition:   Postoperative; Dysfunction Following Cardiac Surgery
Intervention:   Device: Intra-aortic balloon pump.
Sponsor:   University of Sao Paulo
Recruiting - verified February 2016

A Self-efficacy Enhancing Stroke Self-management Program for Community-dwelling Stroke Survivors

Condition:   Stroke
Interventions:   Behavioral: Stroke self-management program;   Behavioral: Usual care
Sponsor:   Queensland University of Technology
Active, not recruiting - verified January 2016

Human-Machine System for the H2 Lower Limb Exoskeleton

Conditions:   Stroke;   Hemiparesis
Interventions:   Behavioral: Robot-assisted training with the H2 lower limb powered exoskeleton;   Behavioral: Supervised motor practice
Sponsors:   University of Houston;   The University of Texas Health Science Center, Houston;   TIRR Memorial Hermann
Recruiting - verified January 2016

Stroke - Sleep Disorders, Dysfunction of the Autonomic Nervous System and Depression

Condition:   Stroke
Intervention:  
Sponsor:   Helle Klingenberg Iversen, MD, DmSc
Recruiting - verified February 2016

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Treatment 90 days DAPT;   Drug: Treatment 360 days DAPT
Sponsor:   Diagram B.V.
Recruiting - verified February 2016

fMRI Neurofeedback for Motor Rehabilitation

Conditions:   Stroke;   fMRI
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified July 2015

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Condition:   Carotid Stenosis
Interventions:   Procedure: Carotid endarterectomy;   Device: Carotid stenting
Sponsors:   Thomas G. Brott, M.D.;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2016

Sequential Expansion of Comparative Effectiveness of Anticoagulants

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)

Condition:   Brain Ischemia
Interventions:   Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
Sponsor:   Genentech, Inc.
Recruiting - verified February 2016

The Comparative Safety and Effectiveness of Warfarin and Dabigatran Prescribed in the Non-valvular Atrial Fibrillation Population With Humana Healthcare Coverage

Condition:   Atrial Fibrillation
Intervention:   Drug: Observational
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism)

Conditions:   Pulmonary Embolism;   Thromboembolism;   Thrombosis;   Venous Thrombosis;   Venous Thromboembolism
Interventions:   Drug: BAY 59-7939;   Drug: BAY 59-7939;   Drug: ASA
Sponsor:   Bayer
Recruiting - verified February 2016

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified February 2016

Biomarkers and Antithrombotic Treatment in Cervical Artery Dissection - TREAT-CAD

Condition:   Cervical Artery Dissection
Interventions:   Drug: Acetylsalicylic acid;   Drug: vitamin K-antagonist
Sponsors:   University Hospital, Basel, Switzerland;   University Hospital Inselspital, Berne;   University of Lausanne Hospitals
Recruiting - verified February 2016

Repetitive Arm Training Combined With Functional Electrical Stimulation on Upper Extremity Motor Recovery in Sub-acute Stroke Survivors

Conditions:   Stroke;   Arm Motor Recovery
Interventions:   Other: conventional therapy;   Device: arm training combined with FES
Sponsor:   University Hospital of Ferrara
Recruiting - verified February 2016

"Evaluation by Transcranial Magnetic Stimulation of the Benefit of Fluoxetine on Motor Recovery After Stroke"

Condition:   Cerebral Infarction
Interventions:   Drug: Fluoxetine;   Drug: Placebo of fluoxetine
Sponsor:   Centre Hospitalier St Anne
Terminated - verified February 2016

Randomized Study Comparing Periodic Acceleration Versus Static Position in Cerebrovascular Stroke Patients

Condition:   Cerebrovascular Stroke
Intervention:   Device: Exer-Rest® TL
Sponsor:   Fundacion Rioja Salud
Recruiting - verified February 2016

Understanding the Exercise-Hypertension Paradox

Condition:   Hypertension
Interventions:   Dietary Supplement: Oral Antioxidant;   Other: Exercise rehabilitation
Sponsor:   VA Office of Research and Development
Recruiting - verified February 2016

RELIEF Study: Lower Limb Pain Relief After Injection Cycles in Adults Suffering From Lower Limb Spasticity Following Stroke

Condition:   Lower Limb Spasticity
Intervention:   Drug: Botulinum Toxin Type A (BoNT-A) Injection
Sponsor:   Ipsen
Recruiting - verified February 2016

Impact of tDCS on Locomotion and Equilibrium in Hemiplegic Patients

Condition:   Gait Disorders
Intervention:   Device: anodal tDCS and sham tDCS stimulations
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified February 2016

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Ticagrelor 60 mg;   Drug: Ticagrelor placebo
Sponsor:   AstraZeneca
Recruiting - verified February 2016

Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects

Condition:   Sialorrhea
Interventions:   Drug: MYOBLOC;   Other: PLACEBO
Sponsor:   US WorldMeds LLC
Active, not recruiting - verified February 2016

CareToy - A Modular Smart System for Infants' Rehabilitation at Home Based on Mechatronic Toys

Condition:   Preterms at Risk for Developmental Disorders
Interventions:   Device: CareToy;   Other: Standard Care
Sponsors:   IRCCS Fondazione Stella Maris;   BioRobotics Institute - Scuola Superiore Sant'Anna, Italy;   STMicroelectronics SRL, Italy;   University of Ljubljana;   University of Hamburg;   Fonden for Helen Elsass Center, Denmark;   Marketing Research & Development SPA, Italy
Completed - verified February 2016

Repository Study of Autosomal Dominant Polycystic Kidney Disease

Condition:   Autosomal Dominant Polycystic Kidney Disease
Intervention:  
Sponsors:   The Rogosin Institute;   Weill Medical College of Cornell University;   New York Presbyterian Hospital
Recruiting - verified February 2016

Power Training Post-stroke

Condition:   Stroke
Intervention:   Behavioral: POWER training
Sponsor:   VA Office of Research and Development
Recruiting - verified February 2016

Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer

Conditions:   Rivaroxaban;   Cancer-associated Thrombosis;   Recurrence;   Bleeding
Intervention:   Drug: Rivaroxaban
Sponsors:   Seoul National University Hospital;   Korean Society of Hematology Thrombosis Working Party
Recruiting - verified February 2016

Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer

Conditions:   Breast Cancer;   Breast Tumors;   Cancer of Breast
Interventions:   Drug: Metformin;   Drug: Atorvastatin;   Procedure: Breast surgery
Sponsor:   Columbia University
Recruiting - verified February 2016

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified February 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified February 2016

Clinical Effect Size of an Educational Intervention in the Home and Compliance on People Who Suffer From Stroke

Condition:   Stroke
Interventions:   Behavioral: Educational intervention;   Device: Smartphone-based application
Sponsor:   University of Malaga
Completed - verified February 2015

Detection and Neurological Impact of CerebroVascular Events In Noncardiac Surgery PatIents: A COhort EvaluatioN

Condition:   Covert Postoperative Stroke
Intervention:  
Sponsors:   Hamilton Health Sciences Corporation;   McMaster University
Recruiting - verified February 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified January 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified January 2016

Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Drug: Apixaban;   Drug: aspirin
Sponsors:   Population Health Research Institute;   Bristol-Myers Squibb;   Pfizer;   Medtronic
Recruiting - verified February 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified February 2016

Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)

Condition:   HIV-1 Infection
Intervention:   Drug: Telmisartan
Sponsors:   AIDS Clinical Trials Group;   National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting - verified January 2016

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified February 2016

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

Condition:   Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Withdrawn - verified February 2016

Exercise Education for Adults With Seizure Disorders

Conditions:   Seizures;   Epilepsy
Interventions:   Other: Patient Education;   Other: exercise: increase physical activity/goal setting
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified January 2016

Arm Spasticity - Non-Interventional Study Early BIRD (BoNT Treatment: Initial and Repeated Documentation) [AS-NIS Early BIRD]

Condition:   Post-stroke Arm Spasticity
Intervention:  
Sponsor:   Ipsen
Recruiting - verified February 2016

A Registry to Evaluate the Direct Flow Medical Transcatheter Aortic Valve System

Condition:   Aortic Valve Stenosis
Intervention:   Device: Aortic Valve Replacement
Sponsor:   Direct Flow Medical, Inc.
Recruiting - verified February 2016

Non-Heme Iron Load Quantification in the Brain on MRI in Patients With Hemorrhagic Stroke

Condition:   Stroke
Intervention:   Other: Non heme iron levels on MRI
Sponsor:   University of Michigan
Recruiting - verified February 2016

Anticoagulant Utilization Pattern

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

A Pilot Study of Minocycline in Intracerebral Hemorrhage Patients

Condition:   Intracerebral Hemorrhage
Intervention:   Drug: Minocycline
Sponsors:   Georgia Regents University;   American Heart Association
Recruiting - verified February 2016

A New Multi-parameter Neuromonitoring System to Save Patients' Lives in Stroke and Brain Injury

Conditions:   Subarachnoid Hemorrhage;   Optical Imaging
Intervention:   Device: NeMo Patch and NeMo Probe
Sponsors:   NeMoDevices AG;   Medical University of Graz;   University of Zurich
Recruiting - verified February 2016

Study Evaluating the Safety,Tolerability and Efficacy of PF-04360365 in Adults With Probable Cerebral Amyloid Angiopathy

Condition:   Cerebral Amyloid Angiopathy
Interventions:   Biological: Ponezumab;   Other: placebo
Sponsor:   Pfizer
Completed - verified February 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified February 2016

High Intensity Interval Training in Chronic Stroke Patients

Condition:   Stroke
Interventions:   Other: High intensity aerobic training;   Other: High Intensity Strength Training;   Other: Mixed Training
Sponsor:   Universita di Verona
Recruiting - verified February 2016

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa (Dabigatran etexilate mesilate)
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

Determining Oral Phosphate Tolerance Across the Spectrum of Glomerular Filtration Rate

Condition:   Chronic Kidney Disease
Intervention:   Drug: Phoslax
Sponsor:   Queen's University
Recruiting - verified January 2016

Enoxaparin Versus Aspirin in Patients With Cancer and Stroke

Condition:   Cancer Patients First-ever Acute Ischemic Stroke
Interventions:   Drug: Enoxaparin;   Drug: Aspirin
Sponsors:   Memorial Sloan Kettering Cancer Center;   New York Presbyterian Hospital;   Weill Medical College of Cornell University
Recruiting - verified February 2016

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Asia

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified February 2016

Effects of Vitamin D and Omega-3 Fatty Acids on Infectious Diseases and hCAP18 (VITAL Infection)

Conditions:   Infections;   Human Cathelicidin Antimicrobial Peptide (hCAP-18)
Interventions:   Dietary Supplement: vitamin D3;   Drug: omega-3 fatty acids (fish oil);   Dietary Supplement: Vitamin D3 placebo;   Dietary Supplement: fish oil placebo
Sponsor:   Brigham and Women's Hospital
Active, not recruiting - verified February 2016

Influence of Timing on Motor Learning

Condition:   Cerebrovascular Accident
Interventions:   Other: Conventional hand exercise;   Device: MusicGlove;   Other: Conventional Arm Exercise;   Device: Resonating Arm Exerciser
Sponsors:   University of California, Irvine;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Active, not recruiting - verified February 2016

A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities

Condition:   Cardiovascular Disease, Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: aleglitazar
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours

Condition:   Acute Stroke
Interventions:   Device: Solitaire FR device;   Other: Medical treatment
Sponsors:   Fundacio Ictus Malaltia Vascular;   Medtronic - MITG
Terminated - verified February 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified February 2016

Brain P-gp and Inflammation in People With Epilepsy

Condition:   Epilepsies, Partial
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2016

Impact of Vitamin D Supplementation on Cardiac Structure and Function

Condition:   Cardiovascular Disease
Interventions:   Dietary Supplement: Vitamin D3 + fish oil/fish oil placebo;   Dietary Supplement: Vitamin D3 placebo + fish oil/fish oil placebo
Sponsors:   Massachusetts General Hospital;   Brigham and Women's Hospital
Active, not recruiting - verified February 2016

COAPT Clinical Trial

Conditions:   Mitral Regurgitation;   Mitral Valve Regurgitation
Intervention:   Device: MitraClip System
Sponsors:   Evalve;   Abbott Vascular
Recruiting - verified February 2016

Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility

Condition:   Multiple Sclerosis
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified December 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified January 2016

Xarelto [SPAF] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban(Xarelto, BAY59-7939)
Sponsor:   Bayer
Active, not recruiting - verified February 2016

Xarelto [SPAF-QOL] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban (Xarelto_ BAY59-7939)
Sponsor:   Bayer
Recruiting - verified February 2016

Study in Parkinson's Disease of Exercise

Condition:   Parkinson Disease
Interventions:   Behavioral: Moderate Exercise;   Behavioral: Vigorous Exercise;   Behavioral: No Intervention
Sponsors:   University of Colorado, Denver;   University of Illinois at Chicago;   University of Pittsburgh;   Rush University Medical Center;   National Institute of Neurological Disorders and Stroke (NINDS);   Northwestern University
Active, not recruiting - verified February 2016

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   New York University School of Medicine;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University
Recruiting - verified January 2016

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2016

Effect of HAART Vs. Statin Treatment on Endothelial Function and Inflammation/Coagulation

Condition:   HIV-1 Infection
Interventions:   Drug: Pravastatin sodium;   Drug: Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate;   Drug: Pravastatin sodium
Sponsors:   AIDS Clinical Trials Group;   National Institute of Allergy and Infectious Diseases (NIAID)
Withdrawn - verified January 2016

Effects of Hormone Stimulation on Brain Scans for Cushing s Disease

Condition:   Pituitary Neoplasm
Intervention:   Drug: Acthrel
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified April 2015

Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders

Conditions:   Amyotrophic Lateral Sclerosis;   Frontotemporal Dementia;   PLS;   Motor Neuron Disease;   Lou Gehrigs Disease;   Familial Disease;   Amyotrophic Lateral Sclerosis, Sporadic;   Muscular Dystrophy;   Miyoshi Myopathy
Intervention:  
Sponsors:   University of Massachusetts, Worcester;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2016

The PERFusion Use in Stroke Evaluation Study

Condition:   Ischemic Stroke
Intervention:   Other: Computed tomography perfusion imaging
Sponsors:   California Pacific Medical Center Research Institute;   California Pacific Medical Center
Recruiting - verified February 2016

Brain SPECT Following Cialis (Tadalafil ) Administration

Condition:   Change in Brain Perfusion
Intervention:  
Sponsor:   Wolfson Medical Center
Completed - verified February 2016

The Effects of a Rhythm and Music-based Therapy Program and Therapeutic Riding in Late Recovery Phase Following Stroke

Condition:   Stroke
Interventions:   Other: RGRM;   Other: Therapeutic riding;   Other: Receives no intervention
Sponsors:   Göteborg University;   The Sten A Olsson foundation for Research and Culture
Recruiting - verified February 2016

Study of the Natural History of FFR Guided Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea;   St. Jude Medical (Hong Kong) Limited
Recruiting - verified February 2016

Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain

Conditions:   Autoimmune Diseases;   Systemic Inflammatory Process;   Knee Pain Chronic;   Osteoarthritis;   Rheumatoid Arthritis
Interventions:   Drug: Fish Oil;   Dietary Supplement: Vitamin D;   Other: placebo pill
Sponsors:   Brigham and Women's Hospital;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Active, not recruiting - verified January 2016

Remote Ischemic Preconditioning in High Risk Cardiovascular Surgery Patients

Conditions:   Death;   Stroke;   Low Cardiac Output Syndrome;   Myocardial Infarction;   Renal Failure;   Pulmonary Failure
Interventions:   Other: Remote ischemic preconditioning stimulus;   Other: control
Sponsor:   Queen's University
Completed - verified February 2016

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves

Condition:   Symptomatic Severe Aortic Stenosis
Interventions:   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified February 2016

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement

Condition:   Severe Aortic Stenosis
Interventions:   Device: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI);   Device: Surgical Aortic Valve Replacement (SAVR)
Sponsor:   Medtronic Cardiovascular
Active, not recruiting - verified January 2016

Evaluation of Blood Brain Barrier Permeability in Chronic Stroke

Condition:   A Positive or a Negative Brain SPECT
Intervention:  
Sponsor:   Wolfson Medical Center
Completed - verified February 2016

Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates

Condition:   Essential Tremor
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified March 2015

Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury

Conditions:   Traumatic Brain Injury;   Stroke;   Headache;   PTSD
Intervention:  
Sponsors:   National Institute of Neurological Disorders and Stroke (NINDS);   United States Department of Defense;   Center for Neuroscience and Regenerative Medicine (CNRM);   National Institutes of Health Clinical Center (CC)
Recruiting - verified January 2016

Post Stroke Psychological Distress

Condition:   Stroke
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   German Federal Ministry of Education and Research
Recruiting - verified February 2016

A Prospective Natural History Study of Patients With Syringomyelia

Conditions:   Syringomyelia;   Arnold Chiari Deformity
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified November 2015

BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME).

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: BI 10773 low dose;   Drug: Placebo BI 10773 high dose;   Drug: BI 10773 high dose;   Drug: Placebo BI 10773 low dose;   Drug: Placebo BI 10773 low dose;   Drug: Placebo BI 10773 high dose
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Completed - verified February 2016

Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft Angioplasty

Condition:   Saphenous Vein Graft Atherosclerosis
Interventions:   Device: Bare Metal Stent;   Device: Drug-Eluting Stent;   Drug: Blinded clopidogrel;   Drug: Placebo;   Drug: Thienopyridine (open-label)
Sponsor:   VA Office of Research and Development
Active, not recruiting - verified February 2016

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

SISTERS: Spasticity In Stroke Study - Randomized Study

Condition:   Severe Spasticity
Intervention:   Drug: intrathecal baclofen
Sponsor:   Medtronic International Trading Sarl
Active, not recruiting - verified February 2016

Transcranial Direct Current Stimulation (tDCS) in Chronic Stroke Recovery

Condition:   Stroke
Intervention:   Device: tDCS
Sponsor:   University of Texas Southwestern Medical Center
Recruiting - verified February 2016

Autologous Cell Therapy After Stroke

Condition:   Stroke
Interventions:   Biological: autologous bone marrow mononuclear cell transfusion;   Biological: marrow stromal cells;   Drug: placebo
Sponsors:   University of California, Irvine;   University of California, San Diego
Withdrawn - verified February 2016

Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System

Conditions:   Central Nervous System Disease;   Multiple Sclerosis
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified March 2015

Polycystic Kidney Disease Data Repository

Condition:   Polycystic Kidney Disease
Intervention:  
Sponsors:   The Rogosin Institute;   Weill Medical College of Cornell University;   New York Presbyterian Hospital
Recruiting - verified February 2016

A Study of All-Cause Mortality and Cardiovascular Morbidity in CKD Patients on Dialysis and Those Not on Renal Replacement Therapy Receiving Mircera or Reference ESAs.

Condition:   Anemia
Interventions:   Drug: ESAs (darbepoetin alfa, epoetin alfa or epoetin beta);   Drug: methoxy polyethylene glycol-epoetin beta [Mircera];   Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified February 2016

Blood Markers of Inflammation, Blood Clotting and Blood Vessel Function in HIV-infected Adults

Condition:   HIV
Intervention:  
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified January 2016

Canadian Fabry Disease Initiative (CFDI) Enzyme Replacement Therapy (ERT) Study

Condition:   Fabry Disease
Interventions:   Drug: agalsidase alfa;   Drug: Agalsidase beta
Sponsors:   Canadian Fabry Research Consortium;   Nova Scotia Health Authority
Recruiting - verified February 2016

Hu Mik-Beta-1 to Treat HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis

Condition:   HTLV-1
Intervention:   Drug: Hu MiK-Beta-1
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified March 2015

In Vitro Studies on Pharmacological Regulation and Genetic Risk Factors of Peripheral Human Nociceptors

Condition:   Pain
Intervention:  
Sponsors:   The University of Texas Health Science Center at San Antonio;   National Institutes of Health (NIH);   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified February 2016

Cardiac and Renal Disease Study (CARDS)

Conditions:   Coronary Disease;   Cardiovascular Diseases;   Cerebrovascular Accident;   Heart Failure;   Heart Diseases;   Peripheral Vascular Diseases;   Diabetes Mellitus;   Hypertension;   Kidney Failure, Chronic
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2006

Screening and Natural History: Primary Lateral Sclerosis and Related Disorders

Condition:   Primary Lateral Sclerosis
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified July 2015

Retinal Arteriolar Abnormalities and CV Mortality

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Cerebrovascular Disorders;   Coronary Disease
Intervention:  
Sponsors:   University of Wisconsin, Madison;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016

Natural History of Stroke: Cause and Development

Conditions:   Nervous System Disease;   Transient Ischemic Attack;   Neurologic Disorders;   Stroke;   Vascular Disease
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2015

Stroke and MI in Users of Estrogen/Progestogen

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Cerebrovascular Accident;   Myocardial Infarction;   Postmenopause
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified May 2000

Postmenopausal Progestins, MI and Stroke

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Cerebrovascular Accident;   Myocardial Infarction;   Postmenopause
Intervention:  
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified June 2000

Homocyst(e)Ine, Vitamin Status, and CVD Risk

Conditions:   Cardiovascular Diseases;   Cerebrovascular Accident;   Coronary Disease;   Myocardial Infarction;   Heart Diseases;   Hyperhomocysteinemia
Intervention:  
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified June 2000

Minnesota Heart Survey - Risk Factor Survey

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Cerebrovascular Accident;   Coronary Disease;   Hypertension;   Myocardial Infarction
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016

Epidemiology of Cardiovascular and Non-Cardiovascular Risk In Chicago

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Cerebrovascular Disorders;   Diabetes Mellitus;   Hypertension;   Cerebrovascular Accident
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

Community Structure and Cardiovascular Mortality Trends

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Myocardial Ischemia;   Cerebrovascular Disorders;   Cerebrovascular Accident
Intervention:  
Sponsors:   University of North Carolina, Chapel Hill;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016

Study of Inherited Neurological Disorders

Conditions:   Ataxia;   Motor Neuron Disease;   Muscular Disease;   Muscular Dystrophy;   Peripheral Nervous System Disease
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified January 2016