Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Stroke Imaging Package Study

Conditions:   Atherosclerosis;   Stroke;   Infarction, Middle Cerebral Artery;   Vertebrobasilar Insufficiency;   Cerebral Small-vessel Disease;   Moyamoya Syndrome
Intervention:  
Sponsors:   Wei-Hai Xu;   Peking University First Hospital;   Peking Union Medical College Hospital;   General Hospital of Chinese Armed Police Forces;   Daping Hospital and the Research Institute of Surgery of the Third Military Medical University;   General Hospital of Shenyang Military Region;   Subei People's Hospital of Jiangsu Province;   Second Affiliated Hospital, School of Medicine, Zhejiang University;   Beijing Jishuitan Hospital;   Beijing Friendship Hospital;   Fuxing Hospital of Capital Medical University;   Fujian Medical University;   Jingan District Central Hospital of Shanghai (Jingan Branch of Huashan Hospital Affiliated to Fudan University);   First Hospital of Jilin University;   The First Affiliated Hospital of University of South China;   Qilu Hospital of Shandong University (Qingdao);   Tangshan Gongren Hospital;   Wuhan University;   Third Affiliated Hospital, Sun Yat-Sen University;   Renmin Hospital of Wuhan University;   Qilu Hospital;   Qingdao Municipal Hospital
Not yet recruiting - verified June 2015

Validation of Nicom Device to Measure Stoke Volume Variation

Condition:   Anesthesia
Interventions:   Procedure: Volume loading;   Drug: Ringer solution
Sponsor:   Hopital Foch
Recruiting - verified June 2015

A New Rehabilitation Treatment Following Stroke

Condition:   Unisensory vs. Multisensory Stimulation Delivered During the Acute vs. Chronic Phase Following Stroke
Intervention:   Behavioral: A New Rehabilitation Treatment following Stroke
Sponsor:   University of Oxford
Recruiting - verified June 2015

PreventIon of IMT Progression in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage-IMT Study

Conditions:   Brain Ischemia;   Intracranial Hemorrhages
Interventions:   Drug: cilostazol;   Drug: Probucol;   Drug: Aspirin;   Drug: placebo of cilostazol;   Drug: Placebo of aspirin;   Device: Intima-medial thickness
Sponsors:   Asan Medical Center;   Korea Otsuka Pharmaceutical Co.,Ltd.
Active, not recruiting - verified June 2015

Ankle Robot to Reduce Foot-drop in Stroke

Conditions:   Stroke;   Foot-drop
Interventions:   Device: Treadmill plus anklebot;   Behavioral: Treadmill only
Sponsor:   Department of Veterans Affairs
Not yet recruiting - verified June 2015

Self-regulated Constraint-induced Movement Therapy in Subacute Stroke Patients

Condition:   Stroke
Interventions:   Other: Self-regulated constraint-induced movement therapy;   Other: Constraint-induced movement therapy;   Other: Conventional occupational therapy
Sponsors:   University of Western Sydney;   The Hong Kong Polytechnic University
Completed - verified June 2015

Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis

Conditions:   End Stage Renal Failure on Dialysis;   Body Fluid Retention;   Impedance;   Cardiac Output, Low
Interventions:   Device: CardioScreen 1000 - Haemodynamic Measurement System, Medis;   Device: BCM- Body Composition Monitor, Fresenius Medical Care;   Device: SCHILLER, BR-102 plus, Ambulatory Blood Pressure Monitoring System
Sponsor:   Medical University of Warsaw
Recruiting - verified June 2015

Assessment and Quantification of Collateral by ASL MRI

Condition:   Stroke
Intervention:  
Sponsors:   Chinese PLA General Hospital;   Beijing Tiantan Hospital
Recruiting - verified June 2015

Effect of Rosuvastatin on Prognosis of Clinical Response in Acute Ischemic Stroke Patients(REPAIRS)

Condition:   Infarction, Anterior Cerebral Artery
Intervention:   Drug: Rosuvastatin
Sponsors:   Second Affiliated Hospital of Soochow University;   Taicang No.1 People’s hospital;   AstraZeneca;   National Natural Science Foundation of China
Not yet recruiting - verified June 2015

Early Sleeve Gastrectomy In New Onset Diabetic Obese Patients

Condition:   Type 2 Diabetes Mellitus
Interventions:   Procedure: Laparoscopic Sleeve Gastrectomy plus conventional medical therapy;   Drug: Conventional medical therapy
Sponsors:   Azienda Ospedaliera Santa Maria, Terni, Italy;   Ethicon Endo-Surgery
Not yet recruiting - verified June 2015

Lacunar Intervention Trial 1 (LACI-1)

Conditions:   Cerebral Small Vessel Diseases;   Cognitive Impairment;   Stroke
Interventions:   Drug: isosorbide mononitrate;   Drug: cilostazol
Sponsors:   University of Edinburgh;   University of Nottingham
Not yet recruiting - verified June 2015

A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care

Conditions:   Pain;   Chronic Pain;   Mental Disorders;   Cardiovascular Diseases;   Diabetes Mellitus, Type 2;   Arthritis
Interventions:   Other: Unblinded to Genetic Testing Results;   Other: Blinded to Genetic Testing Results
Sponsor:   Proove Bioscience, Inc.
Recruiting - verified June 2015

Risk of Intracranial Hemorrhage in Users of Oral Antithrombotic Drugs

Conditions:   Intracranial Hemorrhages;   Stroke
Intervention:   Drug: antithrombotic drugs
Sponsors:   St. Olavs Hospital;   Norwegian University of Science and Technology
Active, not recruiting - verified June 2015

The Risk of Major Bleeding With Novel Anti-platelets: A Comparison of Ticagrelor With Clopidogrel in a Real World Population of 5000 Patients Treated for Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Bleeding;   Novel Anti-platelets;   Ticagrelor;   Clopidogrel
Intervention:   Drug: Ticagrelor
Sponsors:   Aintree University Hospitals NHS Foundation Trust;   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Royal Liverpool and Broadgreen University Hospitals NHS Trust;   Countess of Chester NHS Foundation Trust;   St Helens & Knowsley Teaching Hospitals NHS Trust
Recruiting - verified June 2015

Comparison Between Thoracoscopic Left Atrial Appendage Excision and Warfarin for the Secondary Prevention of Stroke in Patients With AF

Conditions:   Atrial Fibrillation;   Stroke;   Systemic Embolism
Interventions:   Procedure: Thoracoscopic Left Atrial Appendage Excision;   Drug: Warfarin
Sponsor:   The First Hospital of Nanjing Medical University
Active, not recruiting - verified June 2015

App-delivered Therapy for Arabic Readers With Hemianopic Alexia

Condition:   Stroke
Intervention:   Behavioral: Reading Training
Sponsor:   University College London Hospitals
Not yet recruiting - verified June 2015

Evaluation of Transcutaneous Trigeminal Nerve Stimulation for Prevention of Cerebral Vasospasm After Subarachnoid Haemorrhage

Condition:   Subarachnoid Haemorrhage (SAH)
Intervention:   Device: Transcutaneous Electrical Nerve Stimulation (TENS)
Sponsor:   Poitiers University Hospital
Not yet recruiting - verified June 2015

Acupuncture for Ischemic Post-stroke Depression

Condition:   Post-stroke Depression
Interventions:   Device: acupuncture;   Drug: placebo;   Device: sham-acupoint acupuncture;   Drug: Fluoxetine
Sponsors:   Menghan Li;   State Administration of Traditional Chinese Medicine of the People's Republic of China
Not yet recruiting - verified June 2015

Family-based Approach to Promotion of Health Project 2

Conditions:   Lifestyle Intervention;   Atherosclerosis;   Cardiovascular Risk Factor
Interventions:   Behavioral: Intensive Individual Intervention Program;   Behavioral: Peer-To-Peer Program Intervention
Sponsors:   Icahn School of Medicine at Mount Sinai;   American Heart Association
Not yet recruiting - verified June 2015

Perioperative Goal Directed Hemodynamic Therapy Based on Noninvasive Monitoring in Patients With Hip Fracture

Condition:   Hip Fractures
Interventions:   Other: PGDT based on noninvasive monitoring;   Device: System ClearSight® and Platform EV Clinic 1000®
Sponsor:   Althaia Xarxa Assistencial Universitària de Manresa
Recruiting - verified June 2015

A Predictive Score for the Ischemic Etiology of a Transient Visual Disturbances (VASCO)

Condition:   Vision Disorders
Intervention:   Other: Clinical, ophthalmological and neurological evaluation
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified June 2015

Nephrologist Follow-up Versus Usual Care After Acute Kidney Injury

Conditions:   Acute Kidney Injury;   Chronic Kidney Disease
Intervention:   Behavioral: AKI Follow-up Clinic
Sponsors:   St. Michael's Hospital, Toronto;   Sunnybrook Health Sciences Centre;   University Health Network, Toronto;   Mount Sinai Hospital, Canada
Not yet recruiting - verified June 2015

Real Evidence of Anticoagulation Treatment in Non-valvular Atrial Fibrillation in Germany and the UK: REACT-AF2

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Bristol-Myers Squibb;   IMS Health;   Oxon Epidemiology
Active, not recruiting - verified June 2015

"Mobile Stroke Unit"-Concept for Delivery of Specialized Acute Stroke Care to Patients in Remote Areas

Condition:   Acute Stroke
Interventions:   Device: MSU-based stroke management;   Device: Control stroke management
Sponsor:   University Hospital, Saarland
Recruiting - verified July 2015

Real-Life Evidence on Stroke Prevention in SPAF

Condition:   Atrial Fibrillation (Prevention of Stroke)
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Vitamin K antagonists
Sponsors:   Bayer;   Janssen, LP
Recruiting - verified June 2015

Vascular Responses to UV Exposure in Pregnancy

Condition:   Pregnancy
Interventions:   Radiation: UVA radiation;   Radiation: Sham Control
Sponsors:   University of Edinburgh;   NHS Lothian
Not yet recruiting - verified June 2015

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Not yet recruiting - verified June 2015

Unilateral vs. Bilateral Approaches to Hybrid Stroke Rehabilitation

Condition:   Stroke
Interventions:   Procedure: Unilateral Hybrid Intervention;   Procedure: Bilateral Hybrid Intervention;   Device: BMT robot;   Other: Training;   Procedure: Robot-Assisted Training
Sponsor:   Chang Gung Memorial Hospital
Enrolling by invitation - verified April 2015

Cognitive Behavioural Therapy for Menopausal Symptoms

Condition:   Menopausal Depression
Intervention:   Other: Cognitive Behavioural Therapy for Menopausal Symptoms
Sponsors:   St. Joseph's Healthcare Hamilton;   Ontario Mental Health Foundation
Not yet recruiting - verified June 2015

Study to Document the Effectiveness of Dysport in Patients Suffering From Upper Limb Spasticity (ULS) After Stroke

Condition:   Post Stroke Arm Spasticity
Intervention:  
Sponsor:   Ipsen
Recruiting - verified June 2015

Safety Study of the PulseRider® in Patients Undergoing Treatment for Bifurcation Intracranial Aneurysms

Condition:   Brain Aneurysm
Intervention:   Device: PulseRider
Sponsors:   Pulsar Vascular;   Medpace, Inc.
Recruiting - verified June 2015

Evaluation the Effectiveness of the Risk Minimisation Activities in the Treatment of Stroke Prevention in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Study on the Use of Botulinum Toxin Type A in the Treatment of Chronic Post-stroke Spastic Patients

Condition:   Spasticity
Intervention:  
Sponsor:   Ipsen
Recruiting - verified June 2015

Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)

Conditions:   Vertigo;   Dizziness
Intervention:   Device: VRT Care
Sponsors:   David E. Newman-Toker, MD PhD;   National Institute on Deafness and Other Communication Disorders (NIDCD);   GN Otometrics
Not yet recruiting - verified June 2015

Robotic Therapy and Transcranial Direct Current Stimulation in Patients With Stroke

Condition:   Stroke
Interventions:   Device: Robotic Therapy;   Device: Active tDCS;   Device: Sham tDCS;   Other: Physical Therapy;   Other: Occupational Therapy
Sponsors:   University of Sao Paulo General Hospital;   Conselho Nacional de Desenvolvimento Científico e Tecnológico
Recruiting - verified June 2015

Canadian Community Utilization of Stroke Prevention Study - Emergency Department

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Other: Retrospective review of OAC prescription;   Other: Prescription of OAC in ED;   Other: Community AF clinic
Sponsor:   Population Health Research Institute
Recruiting - verified June 2015

Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial

Conditions:   Coronary Artery Disease;   Coronary Disease;   Myocardial Ischemia;   Arteriosclerosis;   Cardiovascular Diseases
Interventions:   Procedure: Fractional flow reserve-guided CABG;   Procedure: Angiography-guided CABG
Sponsor:   Odense University Hospital
Recruiting - verified June 2015

Patient and Provider Assessment of Lipid Management Registry

Conditions:   Hyperlipidemia;   Hypercholesterolemia;   Cardiovascular Disease;   Diabetes;   Chronic Kidney Disease (CKD);   Hypertension;   Smoking;   Myocardial Infarction (MI);   Unstable Angina;   Angina;   Coronary Artery Disease (CAD);   Stroke;   Transient Ischemic Attack (TIA);   Carotid Stenosis;   Peripheral Arterial Disease;   Atherosclerosis;   Claudication
Intervention:  
Sponsors:   Duke University;   Regeneron Pharmaceuticals;   Sanofi
Recruiting - verified June 2015

Community Engagement for Early Recognition and Immediate Action in Stroke

Condition:   Ischemic Stroke
Intervention:   Behavioral: Community-based Stroke Awareness Program
Sponsors:   Northwestern University;   Patient Centered Outcome Research Institute
Recruiting - verified June 2015

Intra-arterial Autologous Bone-marrow Mononuclear Cells Infusion for Acute Ischemic Stroke

Condition:   Stroke
Interventions:   Drug: Autologous bone marrow mononuclear stem cells;   Other: No intervention
Sponsors:   Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud;   Iniciativa Andaluza en Terapias Avanzadas 
Recruiting - verified May 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified June 2015

ETREAT Study on Effectiveness of Botulinum Toxin Type A Injections to Treat Post-stroke Upper and/or Lower Limb Spasticity

Condition:   Spasticity
Intervention:  
Sponsor:   Ipsen
Recruiting - verified June 2015

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability

Conditions:   Chronic Troublesome Sialorrhea;   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Intellectual Disability
Interventions:   Drug: IncobotulinumtoxinA;   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified June 2015

Evaluation of SVV From NICOM as a Predictor of Fluid Responsiveness in Prone Position During Spine Surgery

Conditions:   Fluid Responsiveness;   Prone Position;   Non Invasive Cardiac Output Monitoring
Intervention:   Other: Fluid loading to evaluate fluid responsiveness
Sponsor:   Samsung Medical Center
Recruiting - verified June 2015

SMARTCap Stroke Study: A Field Deployable Blood Test for Stroke

Condition:   Stroke
Intervention:   Device: SMARTCap
Sponsor:   University Hospitals Coventry and Warwickshire NHS Trust
Recruiting - verified June 2015

Evaluation of 5 Days Holter and 30 Days Thumb-ECG for Detection of Atrial Fibrillation in Stroke Patients

Conditions:   Atrial Fibrillation;   Stroke
Intervention:   Device: Holter monitoring and Thumb ECG
Sponsor:   Herlev Hospital
Completed - verified June 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified June 2015

Decompressive Hemicraniectomy in Intracerebral Hemorrhage

Condition:   Cerebral Hemorrhage
Interventions:   Procedure: Decompressive craniectomy (DC) and best medical treatment;   Procedure: Best medical treatment
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified June 2015

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2015

Brain Stimulation and Hand Training in Children With Hemiparesis

Condition:   Pediatric Hemiparesis
Intervention:   Device: Transcranial Direct Current Stimulation (tDCS)
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Cerebral Palsy International Research Foundation (CPIRF)
Recruiting - verified February 2015

The CREST-2 Registry

Condition:   Carotid Artery Diseases
Intervention:   Device: Carotid Artery Stent
Sponsors:   University of Maryland;   National Institute of Neurological Disorders and Stroke (NINDS);   Centers for Medicare and Medicaid Services;   Mayo Clinic;   Society for Vascular Surgery;   American College of Cardiology
Recruiting - verified June 2015

Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVR

Condition:   Peripheral Artery Disease (PAD)
Interventions:   Drug: Ticagrelor;   Drug: Comparator
Sponsors:   AstraZeneca;   CPC Clinical Research
Recruiting - verified June 2015

Active Surveillance Research Program for the Assessment of the Safety and the Effectiveness of Linagliptin

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study

Conditions:   Abdominal Aortic Aneurysm;   Coronary Heart Disease;   Sudden Cardiac Death;   Intracerebral Haemorrhage;   Heart Failure;   Ischemic Stroke;   Myocardial Infarction;   Stroke;   Peripheral Arterial Disease;   Stable Angina Pectoris;   Subarachnoid Haemorrhage;   Transient Ischemic Attack;   Unstable Angina;   Cardiac Arrest
Intervention:  
Sponsors:   University College, London;   Wellcome Trust;   National Institute for Health Research, United Kingdom;   London School of Hygiene and Tropical Medicine
Active, not recruiting - verified July 2015

Efficacy and Security of an Endovascular Treatment as First Choice Procedure Compared With a Standard Intravenous Thrombolytic Therapy Treatment for Patients With Acute Ischemic Stroke Within 4.5 Hours After Onset

Condition:   Acute Ischaemic Stroke
Interventions:   Procedure: EVT (endovascular treatment );   Procedure: IVT (intravenous thrombolytic therapy)
Sponsor:   Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Completed - verified June 2015

Thoratec Corporation HeartMate III™ CE Mark Clinical Investigation Plan

Condition:   Advanced Refractory Left Ventricular Heart Failure
Intervention:   Device: Left Ventricular Assist System (LVAS)
Sponsors:   Thoratec Corporation;   Center for Life Sciences (C3TK);   Emergo Group;   Krakow Cardiovascular Research Institute
Active, not recruiting - verified June 2015

Trevo and Medical Management Versus Medical Management Alone in Wake Up and Late Presenting Strokes

Condition:   Ischemic Stroke
Interventions:   Device: Trevo Thrombectomy Procedure;   Other: Medical Management
Sponsor:   Stryker Neurovascular
Recruiting - verified June 2015

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Recruiting - verified April 2015

Sedation vs. Intubation for Endovascular Stroke TreAtment

Condition:   Acute Ischemic Stroke
Intervention:   Procedure: Endovascular recanalisation
Sponsor:   University Hospital Heidelberg
Recruiting - verified June 2015

Haemodynamic Effects of Apelin Agonists and Antagonists in Man in COPD With Raised Pulmonary Artery Pressures

Conditions:   COPD;   Pulmonary Hypertension
Interventions:   Procedure: Forearm plethysmography;   Procedure: Haemodynamic studies
Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   Wellcome Trust;   University of Cambridge
Completed - verified January 2015

Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation

Condition:   Postoperative Atrial Fibrillation
Interventions:   Drug: Amiodarone;   Procedure: DC-cardioversion;   Drug: Rate Control
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   National Institute of Neurological Disorders and Stroke (NINDS);   Canadian Institutes of Health Research  (CIHR)
Active, not recruiting - verified June 2015

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   The Cleveland Clinic
Recruiting - verified June 2015

Combined Bronchodilators in Chronic Obstructive Pulmonary Disease and the Risk of Adverse Cardio-pulmonary Events

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified July 2015

Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech

Conditions:   Apraxia of Speech;   Aphasia;   Cerebrovascular Accident
Interventions:   Behavioral: Normal Auditory Feedback;   Behavioral: Masked Auditory Feedback;   Behavioral: Altered Auditory Feedback
Sponsors:   University of North Carolina, Chapel Hill;   National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting - verified June 2015

Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions

Conditions:   Chronic Troublesome Sialorrhea;   Parkinson's Disease;   Post-stroke;   Traumatic Brain Injury
Interventions:   Drug: IncobotulinumtoxinA (100 Units);   Drug: IncobotulinumtoxinA (75 Units);   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified June 2015

Sequential Expansion of Comparative Effectiveness of Anticoagulants

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Acute Stroke Advancing Program Using Telemedicine

Condition:   Stroke
Intervention:   Other: Telemedicine consultation system
Sponsors:   Xijing Hospital;   Department of Science and Technology of Shanxi Province;   Fourth Military Medical University
Recruiting - verified September 2014

Heart-Brain Retraining for Stroke Rehabilitation

Condition:   Stroke
Interventions:   Behavioral: Repetitive Task Practice (RTP);   Behavioral: Voluntary cycling + RTP;   Behavioral: Assisted cycling + RTP
Sponsor:   The Cleveland Clinic
Completed - verified June 2015

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)

Condition:   Brain Ischemia
Interventions:   Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
Sponsor:   Genentech, Inc.
Recruiting - verified July 2015

Elite Controller and ART-treated HIV+ Statin Versus ASA Treatment Intervention Study

Condition:   HIV Infection
Interventions:   Drug: Aspirin 81 mg daily;   Drug: Atorvastatin 40 mg daily
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified September 2014

ASIS for Botox in Upper Limb Spasticity

Conditions:   Upper Limb Spasticity Unilaterally in Adults With History of Stroke;   Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors.
Interventions:   Drug: Gadolinium;   Drug: Gadolinium;   Drug: Gadolinium;   Drug: Efficacy of Botox intramuscularly at Week 6;   Drug: Efficacy of Botox intramuscularly at Week 12,;   Drug: Efficacy of Botox intramuscularly at Week 18;   Drug: Efficacy of Botox intramuscularly at Week 24;   Drug: Efficacy of Botox intramuscularly at Week 30;   Drug: Efficacy of Botox subdermally at Week 6;   Drug: Efficacy of Botox subdermally at Week 12;   Drug: Efficacy of Botox subdermally at Week 18;   Drug: Efficacy of Botox subdermally at Week 24;   Drug: Efficacy of Botox subdermally at Week 30;   Drug: Adverse Reactions of Botox intramuscularly;   Drug: Adverse Reactions of Botox subdermally
Sponsor:   li nguyen
Not yet recruiting - verified June 2015

Impact of Continuous Positive Airway Pressure (CPAP) Therapy on Outcomes in Patients Undergoing Coronary Revascularization

Conditions:   Obstructive Sleep Apnea;   Ischaemic Heart Desease
Intervention:   Device: CPAP
Sponsor:   Beijing Anzhen Hospital
Recruiting - verified June 2015

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified June 2015

CRT ShuntCheck "Fit & Function" Study

Condition:   Hydrocephalus
Intervention:   Device: Fit & Function test
Sponsors:   NeuroDx Development;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2015

Examining the Spasmodic Dysphonia Diagnosis and Assessment Procedure (SD-DAP) for Measuring Symptom Change

Conditions:   Spasmodic Dysphonia;   Laryngeal Dystonia
Intervention:  
Sponsors:   Emory University;   National Institute of Neurological Disorders and Stroke (NINDS);   Office of Rare Diseases (ORD)
Not yet recruiting - verified June 2015

Trevo® Retriever Registry Post Market Surveillance

Condition:   Ischemic Stroke
Intervention:  
Sponsor:   Stryker Neurovascular
Recruiting - verified June 2015

CNS and Plasma Amyloid-Beta Kinetics in Alzheimer's Disease

Condition:   Alzheimer's Disease
Intervention:  
Sponsors:   Washington University School of Medicine;   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified June 2015

Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects

Condition:   Sialorrhea
Intervention:   Drug: MYOBLOC
Sponsor:   US WorldMeds LLC
Recruiting - verified June 2015

Prehospital Tranexamic Acid Use for Traumatic Brain Injury

Condition:   Traumatic Brain Injury
Interventions:   Drug: 1 gram Tranexamic Acid (TXA);   Drug: 2 grams TXA;   Drug: 0.9% Sodium Chloride injectable
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI);   U.S. Army Medical Research and Materiel Command;   Canadian Institutes of Health Research  (CIHR);   Heart and Stroke Foundation of Canada;   American Heart Association;   Defence Research and Development Canada
Recruiting - verified June 2015

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

GLORIA-AF Registry Program (Phase II/III)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Acenocoumarol
Sponsor:   Bayer
Recruiting - verified June 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Phenprocoumon
Sponsor:   Bayer
Recruiting - verified June 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified June 2015

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

Condition:   Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Withdrawn - verified July 2015

The Medtronic CoreValve™ Evolut R™ CE Mark Clinical Study

Condition:   Aortic Stenosis
Intervention:   Device: The CoreValve™ Evolut R TAV™ system
Sponsors:   Medtronic Cardiovascular;   Medtronic
Active, not recruiting - verified June 2015

ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study

Condition:   Suspected CSF Shunt Obstruction
Interventions:   Device: ShuntCheck-Micro-Pumper (SCMP);   Device: Imaging
Sponsors:   NeuroDx Development;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2015

ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial

Condition:   End Stage Renal Failure on Dialysis
Interventions:   Drug: Spironolactone;   Drug: Placebo
Sponsors:   University Hospital, Brest;   Central Hospital, Nancy, France;   Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - verified June 2015

Arm Spasticity - Non-Interventional Study Early BIRD (BoNT Treatment: Initial and Repeated Documentation) [AS-NIS Early BIRD]

Condition:   Post-stroke Arm Spasticity
Intervention:  
Sponsor:   Ipsen
Recruiting - verified June 2015

Anticoagulant Utilization Pattern

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Transcranial Direct Current Stimulation for Improving Gait Training in Stroke

Conditions:   Stroke;   Cerebral Vascular Accident
Intervention:   Device: transcranial direct current stim
Sponsors:   University of Arkansas;   University of Central Arkansas
Recruiting - verified June 2015

Evaluation of the Effects of Rehabilitation Using the "Wii" on Upper Limb Kinematics in Chronic Stroke Patients.

Conditions:   Post-stroke Hemiparetic Patients (at Least 6 Months Post Stroke);   Age Between 18-75 Years
Interventions:   Behavioral: WII Rehabilitation;   Behavioral: Traditional rehabilitation
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified June 2015

A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: rivaroxaban 2.5 mg;   Drug: rivaroxaban 15 mg;   Drug: rivaroxaban 10 mg;   Drug: aspirin (ASA);   Drug: vitamin K antagonist (VKA);   Drug: clopidogrel;   Drug: prasugrel;   Drug: ticagrelor
Sponsors:   Janssen Scientific Affairs, LLC;   Bayer
Recruiting - verified June 2015

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified June 2015

The Efficacy of Intensive Nutritional Supplement in Patient With Stroke

Conditions:   Stroke;   Malnutrition
Intervention:   Dietary Supplement: high protein supplement
Sponsors:   Seoul National University Bundang Hospital;   Myongji Hospital
Terminated - verified July 2015

A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)

Condition:   Sickle Cell Disease
Interventions:   Drug: Prasugrel;   Drug: Placebo
Sponsors:   Eli Lilly and Company;   Daiichi Sankyo Inc.
Active, not recruiting - verified June 2015

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Active, not recruiting - verified June 2015

The Effect of Low Frequency STN DBS on Sleep and Vigilance in Parkinson's Disease (PD) Patients

Condition:   Parkinson's Disease
Interventions:   Other: DBS stimulator setting alteration;   Other: virtual reality simulator
Sponsors:   University of Alabama at Birmingham;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2015

Improving Arm and Hand Functions in Chronic Stroke (CIHR 2012-2015)

Conditions:   Stroke;   Upper Extremity Paresis
Interventions:   Behavioral: Music Supported Rehabilitation;   Behavioral: Conventional Upper Extremity Therapy
Sponsor:   Baycrest
Active, not recruiting - verified June 2015

Treatment of Post Stroke Fatigue With a Wakefulness Promoting Agent

Conditions:   Stroke;   Post Stroke Fatigue
Interventions:   Drug: modafinil;   Drug: placebo
Sponsor:   Herlev Hospital
Terminated - verified June 2015

A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities

Condition:   Cardiovascular Disease, Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: aleglitazar
Sponsor:   Hoffmann-La Roche
Completed - verified July 2015

VITAL-DEP: Depression Endpoint Prevention in the VITamin D and OmegA-3 TriaL

Conditions:   Depression;   Depressive Symptoms;   Mood
Interventions:   Dietary Supplement: vitamin D3;   Drug: omega-3 fatty acids (fish oil);   Dietary Supplement: Fish oil placebo;   Dietary Supplement: Vitamin D placebo
Sponsors:   Brigham and Women's Hospital;   National Institute of Mental Health (NIMH)
Active, not recruiting - verified July 2015

Danhong Injection in the Treatment of Acute Ischemic Stroke

Condition:   Acute Stroke
Interventions:   Drug: Danhong injection;   Procedure: Standard medical care;   Drug: placebo
Sponsors:   China  Academy of Chinese Medical Sciences;   China: State Food and Drug Administration
Recruiting - verified June 2015

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aortic Dissection.

Conditions:   Turner Syndrome;   Aortic Aneurysm;   Ischemic Heart Disease;   Hypertension;   Congenital Heart Defect
Intervention:  
Sponsor:   University of Aarhus
Recruiting - verified June 2015

Visual Feedback Therapy for Treating Individuals With Hemiparesis Following Stroke

Conditions:   Hemiparesis;   Stroke
Interventions:   Behavioral: Visual feedback therapy #1;   Behavioral: Visual feedback therapy #2
Sponsor:   Albert Einstein Healthcare Network
Enrolling by invitation - verified June 2015

RESCUE Stroke Caregiver Website to Enhance Discharge Planning

Conditions:   Depression;   Quality of Life;   Self Efficacy;   Recovery of Function;   Stress;   Positive Aspects of Caregiving
Interventions:   Behavioral: Caregiver problem-solving;   Other: Standard Care
Sponsor:   Department of Veterans Affairs
Recruiting - verified June 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified June 2015

Aspirin Withdrawal in Non-ischaemic Cardiomyopathy Study

Condition:   Heart Failure
Interventions:   Drug: Aspirin;   Other: withdrawal of aspirin
Sponsor:   The Alfred
Completed - verified June 2015

Post-Marketing Surveillance of Prazaxa® on the Long-term Use in Patients With Nonvalvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Prazaxa
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified July 2015

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Longitudinal Study of Bone Disease in Children With Mucopolysaccharidoses (MPS) I, II, and VI

Condition:   Mucopolysaccharidoses
Intervention:  
Sponsors:   Los Angeles Biomedical Research Institute;   Rare Diseases Clinical Research Network;   National Institute of Neurological Disorders and Stroke (NINDS);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Children's Hospital & Research Center Oakland;   National Center for Advancing Translational Science (NCATS)
Recruiting - verified June 2015

Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection

Condition:   Esophageal Cancer
Intervention:   Other: fluid optimisation
Sponsor:   University Hospital, Linkoeping
Recruiting - verified June 2015

Mifepristone for Metabolic Syndrome

Conditions:   Endocrine Disease;   Diabetes
Intervention:   Drug: Mifepristone
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified March 2015

ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis

Conditions:   Tetraplegia;   Spinal Cord Injury;   Brachial Plexus Injury;   Muscular Dystrophy;   ALS;   Brainstem Stroke
Intervention:   Device: Implantation of ECoG sensors on the brain surface
Sponsor:   University of Pittsburgh
Completed - verified June 2015

Microelectrode Brain-Machine Interface for Individuals With Tetraplegia

Conditions:   Tetraplegia;   Spinal Cord Injury
Intervention:   Device: Implantation of NeuroPort Arrays in the motor cortex
Sponsors:   University of Pittsburgh;   Department of Defense;   Johns Hopkins University
Recruiting - verified June 2015

Dystonia Coalition Projects

Conditions:   Dystonia;   Voice Disorders
Intervention:  
Sponsors:   Hyder A. Jinnah, MD, PhD;   National Institute of Neurological Disorders and Stroke (NINDS);   Office of Rare Diseases (ORD);   Allergan;   Dystonia Study Group
Recruiting - verified June 2015

A Study of RoActemra/Actemra (Tocilizumab) in Comparison to Etanercept in Patients With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Condition:   Cardiovascular Disease, Rheumatoid Arthritis
Interventions:   Drug: etanercept;   Drug: tocilizumab [RoActemra/Actemra]
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified July 2015

ShuntCheck Versus Radionuclide in Evaluating Shunt Function in Symptomatic NPH Patients

Condition:   Hydrocephalus
Intervention:   Device: ShuntCheck test
Sponsors:   NeuroDx Development;   Sinai Hospital of Baltimore;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2015

Virtual Reality Intervention for Stroke Rehabilitation

Condition:   Stroke
Interventions:   Other: Virtual Reality;   Other: Traditional Therapy
Sponsors:   Sheba Medical Center;   European Commission
Completed - verified June 2015

Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure

Conditions:   Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions:   Drug: Losartan;   Drug: Captopril;   Drug: Placebo
Sponsor:   Vanderbilt University
Recruiting - verified June 2015

MR WITNESS: A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients

Condition:   Acute Stroke
Intervention:   Drug: IV rt-PA
Sponsors:   Lee Schwamm;   National Institute of Neurological Disorders and Stroke (NINDS);   Genentech, Inc.
Recruiting - verified June 2015

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Conditions:   Atherosclerosis;   Hypercholesterolemia
Interventions:   Drug: Statin Drugs;   Other: HMG-CoA Reductase Inhibitors
Sponsor:   National Institutes of Health Clinical Center (CC)
Active, not recruiting - verified April 2015

A Trial of Rosuvastatin in Systemic Lupus Erythematosus

Conditions:   Atherosclerosis;   Systemic Lupus Erythematosus
Interventions:   Drug: Rosuvastatin;   Drug: Placebo
Sponsor:   Imperial College London
Completed - verified June 2015

Strategy for Adequate Blood Pressure Lowering in the Patients With Intracranial Atherosclerosis

Condition:   Brain Ischemia
Interventions:   Procedure: Aggressive BP lowering;   Procedure: modest blood pressure lowering
Sponsors:   Asan Medical Center;   Pfizer
Active, not recruiting - verified June 2015

TomVasc - Vascular Effects of Tomato Extract

Conditions:   Ischemic Heart Disease;   Transient Ischemic Attack;   Stroke;   Peripheral Vascular Disease
Interventions:   Dietary Supplement: Ateronon;   Dietary Supplement: Placebo
Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   Cambridge Theranostics Ltd
Completed - verified July 2012

Risk of Cardiovascular Events in Patients With Type 2 Diabetes Initiating Oral Antidiabetic Treatments

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsors:   Bristol-Myers Squibb;   AstraZeneca;   University of Pennsylvania
Active, not recruiting - verified June 2015

SMN Copy Number Distribution in Mali, West Africa

Condition:   Spinal Muscular Atrophy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified July 2014

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified July 2015

Neuroprotective Study of Electroacupuncture Pretreatment in Patients Undergoing Cardiac Surgery

Conditions:   Stroke;   Brain Injuries
Interventions:   Procedure: non electroacupuncture stimulation;   Procedure: Electroacupuncture pretreatment
Sponsors:   Xijing Hospital;   Fourth Military Medical University
Completed - verified November 2009

PreventIon of CArdiovascular Events in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage

Conditions:   Brain Ischemia;   Intracranial Hemorrhages
Interventions:   Drug: Cilostazol;   Drug: Probucol;   Drug: Aspirin;   Drug: placebo of cilostazol;   Drug: placebo of aspirin;   Device: ankle-brachial index (ABI);   Device: intima-medial thickness (IMT);   Device: new asymptomatic brain hemorrhage;   Device: new ischemic lesions on follow-up FLAIR images
Sponsors:   Asan Medical Center;   Korea Otsuka Pharmaceutical Co.,Ltd.
Active, not recruiting - verified June 2015

BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: D,L-lysine acetylsalicylate (Aspirin, BAY81-8781) 500 mg IV;   Drug: D,L-lysine acetylsalicylate (Aspirin, BAY81-8781) 250 mg IV;   Drug: Acetylsalicylic acid (Aspirin, BAYe4465) 300 mg Tablet
Sponsor:   Bayer
Completed - verified June 2015

Early Goal-directed Volume Resuscitation in Severe Acute Pancreatitis

Condition:   Acute Pancreatitis
Interventions:   Other: PiCCO-parameter-guided volume resuscitation;   Other: Control-group
Sponsor:   Technische Universität München
Recruiting - verified June 2015

Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer

Conditions:   Pain/Cancer;   Pain, Intractable
Interventions:   Drug: (Resiniferatoxin)(RTX);   Drug: Intrathecal Resiniferatoxin
Sponsors:   National Institute of Dental and Craniofacial Research (NIDCR);   National Institute of Neurological Disorders and Stroke (NINDS);   Sorrento Therapeutics, Inc.
Suspended - verified May 2015

Sitagliptin Cardiovascular Outcome Study (MK-0431-082)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Sitagliptin phosphate;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Duke Clinical Research Institute, Oxford Diabetes Trials Unit
Completed - verified June 2015

A Study of All-Cause Mortality and Cardiovascular Morbidity in CKD Patients on Dialysis and Those Not on Renal Replacement Therapy Receiving Mircera or Reference ESAs.

Condition:   Anemia
Interventions:   Drug: ESAs (darbepoetin alfa, epoetin alfa or epoetin beta);   Drug: methoxy polyethylene glycol-epoetin beta [Mircera];   Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
Sponsor:   Hoffmann-La Roche
Recruiting - verified July 2015

A Clinical Trial of IntensiVE Dialysis

Conditions:   Renal Replacement Therapy;   Renal Dialysis;   End Stage Kidney Disease;   End Stage Renal Disease;   Uremia
Intervention:   Procedure: haemodialysis
Sponsors:   The George Institute;   National Health and Medical Research Council, Australia;   Baxter Healthcare Corporation
Completed - verified June 2013

Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence

Conditions:   Ischemic Stroke;   Patent Foramen Ovale;   Atrial Septal Aneurysm;   Migraine
Interventions:   Drug: aspirin;   Drug: Antivitamins K;   Device: Devices for PFO closure
Sponsor:   Assistance Publique - Hôpitaux de Paris
Active, not recruiting - verified June 2015

Cardiology Biobank Registry

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   Emory University
Recruiting - verified June 2015

The Effect of Different Schedules of Functional Task Practice for Improving Hand and Arm Function After Stroke

Conditions:   Cerebrovascular Accident;   Hemiplegia
Interventions:   Behavioral: functional task practice - distributed;   Behavioral: functional task practice - condensed
Sponsor:   Department of Veterans Affairs
Withdrawn - verified June 2015

PreFER Managed Ventricular Pacing (MVP) For Elective Replacement

Condition:   Cardiovascular Diseases
Intervention:   Device: Managed Ventricular Pacing programmed ON/OFF
Sponsor:   Medtronic Bakken Research Center
Completed - verified June 2015

Sleep Apnea: Mechanism and Cerebrovascular Consequences

Conditions:   Sleep Apnea, Obstructive;   Stroke
Intervention:   Drug: acetazolamide
Sponsor:   Department of Veterans Affairs
Withdrawn - verified June 2015

Screening and Natural History: Primary Lateral Sclerosis and Related Disorders

Conditions:   Motor Nueron Disease;   Nervous System Diseases;   Muscle Spasticity;   Diffusion Tensor Imaging;   Disease Progression;   Evoked Potentials, Motor/Physiology
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified September 2014

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