Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Can rTMS Enhance Somatosensory Recovery After Stroke?

Condition:   Stroke
Intervention:   Other: repetitive transcranial magnetic stimulation (rTMS)
Sponsor:   VA Office of Research and Development
Recruiting - verified June 2016

Robot-Assisted Stroke Rehabilitation Based on Patient-Therapist Interactions

Conditions:   Stroke;   Hemiplegia;   Healthy
Intervention:   Device: Rehab InterCap system and 3D Kinect
Sponsor:   University of Pennsylvania
Recruiting - verified May 2016

Confounding Factors in the Detection of Intracranial Hemorrhage With the Infrascanner

Conditions:   Ischemic Stroke;   Brain Tumor;   Brain Surgery;   Intracranial Hemorrhage;   Headache;   Head Trauma
Intervention:   Device: Infrascanner
Sponsor:   Ziekenhuis Oost-Limburg
Not yet recruiting - verified June 2016

Stroke and CPAP Outcome Study 2

Conditions:   Sleep Apnea, Obstructive;   Stroke;   Patient Adherence
Intervention:   Device: Continuous Positive Airway Pressure
Sponsor:   University of Washington
Recruiting - verified June 2016

A Reduction in Time With Electronic Monitoring In Stroke Trial

Conditions:   Acute Ischemic Stroke;   Stroke
Intervention:   Other: real-time visual feedback
Sponsors:   Leiden University Medical Center;   The Dutch Brain Foundation;   Innovation Fund Healthcare Insurers, the Netherlands
Not yet recruiting - verified June 2016

Treadmill Training With Functional Electric Stimulation After Stroke

Condition:   Stroke
Interventions:   Other: Treadmill training with functional electrical stimulation;   Other: Treadmill training without functional electrical stimulation
Sponsor:   National Yang Ming University
Completed - verified June 2016

Enterprise Stent Implantation in the Treatment of Carotid Artery Stenosis With Ischemic Stroke

Condition:   Carotid Artery Stenosis
Interventions:   Device: Enterprise stent implantation;   Drug: Only aspirin medication
Sponsor:   Beijing Chao Yang Hospital
Completed - verified June 2016

Gait Adaptation for Stroke Patients With Augmented Reality

Conditions:   Stroke;   Traumatic Brain Injury;   Spinal Cord Injury
Interventions:   Device: Gait training with augmented reality;   Device: Standard training
Sponsors:   Philippe Terrier;   Swiss Heart Foundation
Recruiting - verified June 2016

The Metabolism Research of KLK Treating Acute Cerebral Ischemic Stroke: Focus on Drug Frequency-Efficacy Relationship

Condition:   Cerebral Infarction
Intervention:   Drug: Urinary Kallidinogenase for Injection
Sponsor:   Huisheng Chen
Not yet recruiting - verified June 2016

Does Sedation Depth (as Evaluated by the Bispectral Index) Influence Dynamic Indices of Preload Dependence?

Condition:   Thoracic Surgery
Intervention:   Device: transthoracic echocardiography
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified June 2016

Aphasia Therapy: Factors of Efficacy

Condition:   Aphasia
Interventions:   Other: Control group;   Other: CIAT-group;   Other: communication treatment group (CTG)
Sponsor:   University of Leipzig
Completed - verified June 2016

Effects of Aerobic Training Post-stroke

Condition:   Stroke
Interventions:   Other: Aerobic overground training;   Other: Aerobic treadmill training;   Other: Control (overground walking)
Sponsor:   Federal University of Minas Gerais
Not yet recruiting - verified June 2016

Remote Ischemic Preconditioning for Carotid Endarterectomy

Conditions:   Carotid Stenosis;   Endarterectomy, Carotid
Intervention:   Procedure: Remote Ischemic Preconditioning
Sponsors:   University of Pittsburgh;   Heart and Vascular Institute
Not yet recruiting - verified June 2016

Apixaban Dose Reduction in Patients With Elevated Drug Levels

Condition:   Atrial Fibrillation
Intervention:   Drug: apixaban dose reduction
Sponsors:   Hamilton Health Sciences Corporation;   Population Health Research Institute
Not yet recruiting - verified June 2016

Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction

Conditions:   Myocardial Infarction;   Angioplasty, Balloon, Coronary;   Platelet Aggregation Inhibitors
Interventions:   Drug: Prasugrel;   Drug: Ticagrelor
Sponsor:   Faculty Hospital Kralovske Vinohrady
Active, not recruiting - verified June 2016

Comparison of the Hemodynamic Safety of Two Common Alveolar Recruitment Manoeuvres With Regard to Cardiac Output in a Surgical Intensive Care Unit

Condition:   Positive-Pressure Respiration
Interventions:   Device: echocardiography;   Device: Arterial oximetry
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified June 2016

Nursing Home Care Intervention Post Stroke

Condition:   Stroke
Intervention:   Other: Nursing educational intervention
Sponsor:   Hospital de Clinicas de Porto Alegre
Recruiting - verified June 2016

Enhanced Detection of Underlying, Covert ATrial Fibrillation Using 7-day Holter Electrocardiogram in Patients With Embolic Stroke of Undetermined Source

Condition:   Stroke
Intervention:  
Sponsor:   National Cerebral and Cardiovascular Center
Recruiting - verified June 2016

Evidence Based Best Care Practice for Benign Paroxysmal Positional Vertigo

Condition:   Benign Paroxysmal Positional Vertigo
Intervention:   Behavioral: DIZZTINCT
Sponsors:   University of Michigan;   National Institute on Deafness and Other Communication Disorders (NIDCD)
Not yet recruiting - verified June 2016

Reasons for Prehospital Delay in Patients With Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Intervention:   Other: No Intervention Foreseen
Sponsor:   University Hospital, Basel, Switzerland
Recruiting - verified June 2016

Incheon-Bucheon Cohort of Patients Undergoing Primary PCI for Acute STEMI

Condition:   Myocardial Infarction
Intervention:   Procedure: STEMI treated with primary PCI
Sponsors:   Gachon University Gil Medical Center;   Soon Chun Hyang University;   Sejong General Hospital;   Inha University Hospital
Completed - verified June 2016

Study of DU-176b Aged 80 Years or Older

Condition:   Atrial Fibrillation
Interventions:   Drug: Du-176b;   Drug: placebo
Sponsor:   Daiichi Sankyo Co., Ltd.
Not yet recruiting - verified June 2016

Perioperative Antiplatelet Therapy in Patients With Drug-eluting Stent Undergoing Noncardiac Surgery

Condition:   Antiplatelet Drugs
Interventions:   Drug: Aspirin only;   Drug: No antiplatelet therapy
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified June 2016

A Preliminary Feasibility Efficacy of Participation in Daily Life Promotion Program

Condition:   Stroke
Interventions:   Other: Daily Life Promotion Program;   Other: general rehabilitation treatment
Sponsor:   National Taiwan University Hospital
Not yet recruiting - verified June 2016

Controlling And Lowering Blood Pressure With the MobiusHDTM Device

Condition:   Hypertension
Interventions:   Device: MobiusHD;   Other: Sham Implantation
Sponsor:   Vascular Dynamics, Inc.
Not yet recruiting - verified June 2016

Does Vitamin D Supplementation Enhance Resolution of Inflammation After Community-acquired Pneumonia?

Condition:   Pneumonia
Interventions:   Drug: Vitamin D3 supplementation;   Biological: Peripheral blood and induced sputum sampling;   Radiation: chest CT scans;   Other: Symptom questionnaire
Sponsor:   Queen Mary University of London
Not yet recruiting - verified June 2016

Smart Nitinol Stent System for the Treatment of Severe Atherosclerotic Carotid Stenosis

Condition:   Carotid Artery Stenosis
Interventions:   Device: Smart nitinol stent implantation;   Drug: antiplatelet drug
Sponsor:   Beijing Jishuitan Hospital
Completed - verified June 2016

Age Related D-dimer Evaluation for the Exclusion of a Left Atrium Thrombus in Patients With Atrial Fibrillation (ADDIT-AF)

Condition:   Atrial Fibrillation
Intervention:   Procedure: Blood sampling
Sponsor:   Brugmann University Hospital
Not yet recruiting - verified June 2016

Predicting Development of SCAF in Device Patients

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Genome Canada
Not yet recruiting - verified June 2016

Neurologic Stem Cell Treatment Study

Conditions:   Neurologic Disorders;   Nervous System Diseases;   Neurodegenerative Diseases;   Neurological Disorders
Interventions:   Procedure: Intravenous BMSC;   Procedure: Intranasal BMSC
Sponsors:   Retina Associates of South Florida;   MD Stem Cells
Recruiting - verified June 2016

Effect of FFR Guided Percutaneous Coronary Intervention in Coronary Tandem Lesions

Condition:   Percutaneous Transluminal Coronary Angioplasty
Intervention:   Other: 5 year Follow-up
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified June 2016

Transcatheter Aortic Valve Replacement Single Center Registry in Chinese Population

Condition:   Symptomatic Aortic Stenosis
Intervention:   Procedure: transcatheter aortic valve replacement
Sponsor:   Second Affiliated Hospital, School of Medicine, Zhejiang University
Not yet recruiting - verified June 2016

Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC-TAVI Study

Conditions:   Severe and Symptomatic Aortic Stenosis;   Stable Coronary Disease
Intervention:   Procedure: TAVI procedure
Sponsor:   University Hospital, Montpellier
Not yet recruiting - verified June 2016

Circulatory Management and Acute Kidney Injury in Patients Undergoing Partial Nephrectomy

Condition:   Acute Kidney Injury
Interventions:   Other: Goal-directed circulatory management;   Other: Routine circulatory management
Sponsor:   Peking University First Hospital
Recruiting - verified June 2016

Integrated Primary Care for Diabetes and Cardiovascular Disease

Conditions:   Diabetes Mellitus;   Hypertension;   Heart Failure;   Ischemic Heart Disease;   Cerebrovascular Disease
Interventions:   Behavioral: Outreach education training;   Behavioral: No outreach education training
Sponsors:   University of Sao Paulo General Hospital;   University of Sao Paulo;   Santa Catarina Federal University;   University of Cape Town;   Federal University of Bahia;   Medical Research Council, South Africa;   University of East Anglia
Not yet recruiting - verified June 2016

CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction II (COREA-AMI II)

Conditions:   Acute Myocardial Infarction;   Percutaneous Coronary Intervention;   Major Adverse Cardiovascular Events;   Bleeding
Interventions:   Procedure: Percutaneous coronary intervention;   Drug: Dual-antiplatelet therapy;   Procedure: Percutaneous coronary intervention;   Drug: Dual-antiplatelet therapy
Sponsors:   Seoul St. Mary's Hospital;   The Catholic University of Korea;   Chonnam National University;   AstraZeneca
Recruiting - verified June 2016

Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients

Condition:   Ischemic Stroke
Interventions:   Procedure: remote ischemic postconditioning;   Procedure: sham remote ischemic postconditioning
Sponsor:   Guangzhou University of Traditional Chinese Medicine
Recruiting - verified June 2016

Exercise Intensity of a Walking Related Task-Oriented Exercise in Stroke Survivors

Condition:   Stroke
Intervention:   Procedure: Structured, Progressive, Task-oriented exercise program
Sponsor:   Mahidol University
Not yet recruiting - verified June 2016

Multi- Level and Integrated Analysis of Mechanisms Underlying Atrial Dysfunction

Condition:   Ischemic Heart Disease
Intervention:   Procedure: Cardiac Bypass Surgery
Sponsors:   National Heart Centre Singapore;   Duke-NUS Graduate Medical School
Recruiting - verified May 2016

Optimizing Walking Function of Stroke Survivors by a Task-Oriented Home Exercise Program

Condition:   Stroke
Interventions:   Procedure: Task-oriented home exercise;   Procedure: Usual Physiotherapy Care
Sponsors:   Mahidol University;   University of Medical Technology (Yangon) Myanmar;   National Rehabilitation Hospital, Myanmar;   Yangon General Hospital, Myanmar
Not yet recruiting - verified June 2016

APixaban vs. PhenpRocoumon in Patients With ACS and AF: APPROACH-ACS-AF

Conditions:   Acute Coronary Syndrome;   Atrial Fibrillation;   Coronary Artery Disease
Interventions:   Other: Dual Therapy;   Other: Triple Therapy
Sponsors:   Klinikum der Universitaet Muenchen;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK);   Technische Universität München;   Helmholtz Zentrum München;   University of Göttingen;   University of München;   University Medicine Greifswald
Not yet recruiting - verified May 2016

tDCS in Acute Stroke Patients

Condition:   Acute Stroke
Interventions:   Device: tDCS neuroConn;   Device: Sham stimulation
Sponsors:   Centre Hospitalier St Anne;   Institut National de la Santé Et de la Recherche Médicale, France
Not yet recruiting - verified June 2016

Medtronic CoreValve Evolut R U.S. Clinical Study (Evolut 34R Addendum)

Condition:   Aortic Valve Stenosis
Intervention:   Device: CoreValve Evolut 34R TAVR system
Sponsor:   Medtronic Cardiovascular
Recruiting - verified June 2016

Affordable Mobile Robots for the Elderly

Condition:   Aging
Intervention:   Device: Mobile Service Robot
Sponsors:   University of Pennsylvania;   U.S. National Science Foundation
Recruiting - verified March 2016

Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: natalizumab;   Drug: Placebo
Sponsor:   Biogen
Recruiting - verified June 2016

Basilar Artery Occlusion Chinese Endovascular Trial

Conditions:   Basilar Artery Occlusion;   Ischemic Stroke;   Cerebrovascular Disorders
Interventions:   Procedure: Mechanical embolectomy;   Drug: Medical Treatment
Sponsors:   Xuanwu Hospital, Beijing;   Zhangzhou Municipal Hospital of Fujian Province;   The First People's Hospital of Changzhou;   Xinqiao Hospital of Chongqing;   Changhai Hospital;   Baotou Central Hospital;   The 101st Hospital of Chinese People's Liberation Army;   Linyi People's Hospital;   Zhongshan People's Hospital, Guangdong, China;   PLA 264 Hospital, Taiyuan, Shanxi;   Nanjing First People's Hospital;   Tianjin TEDA Hospital;   The First Affiliated Hospital with Nanjing Medical University;   Liaocheng Third People's Hospital;   Luoyang Central Hospital Affiliated to Zhengzhou University;   Subei People's Hospital of Jiangsu Province;   PLA 148 Hospital, Zibo, Shandong;   Hebei General Hospital;   Shengli Oilfield Hospital;   The 306 Hospital of People's Liberation Army;   Shenzhen Bao'an District People's Hospital;   First Hospital of Jilin University;   Henan Provincial Hospital;   Peking University Binhai Hospital;   Beijing Tiantan Hospital;   The Military General Hospital of Beijing, PLA;   The First Affiliated Hospital of Shanxi Medical University;   The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine;   Beijing Luhe Hospital;   Nantong University;   The Affiliated Hospital Of Guizhou Medical University;   Nanning Second People's Hospital;   Chongqing Three Gorges Central Hospital
Not yet recruiting - verified June 2016

Use of Bemiparine as a Profilaxix Antitrombotic Agent, in Microsurgery for Head and Neck Reconstruction

Condition:   Patients Undergoing Microvascular Surgery
Intervention:  
Sponsors:   Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal;   Rovi Pharmaceuticals Laboratories
Recruiting - verified June 2016

Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy With Ex Vivo Generated Polyomavirus-Specific T-Cells

Condition:   Leukoencephalopathy
Interventions:   Biological: PyVST;   Other: No Intervention
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

tDCS as an Adjuvant to Intensive Speech Therapy for Chronic Post Stroke Aphasia

Conditions:   Aphasia;   Language
Interventions:   Device: Real tDCS;   Device: Sham tDCS;   Other: Intensive Speech Therapy
Sponsors:   Austin Speech Labs;   Burke Medical Research Institute;   University of Texas
Enrolling by invitation - verified June 2016

Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term

Condition:   Atherosclerotic Cardiovascular Disease
Intervention:   Drug: aspirin
Sponsors:   Duke University;   Patient-Centered Outcomes Research Institute;   Mytrus;   Chicago Area Patient Centered Outcomes Research Network;   Greater Plains Collaborative Clinical Data Research Network;   Mid-South Clinical Data Research Network;   Research Action for Health Network;   Patient-Centered Scalable National Network for Effectiveness Research;   PaTH Clinical Data Research Network;   New York City Clinical Data Research Network;   Health eHeart Patient Powered Network
Enrolling by invitation - verified January 2016

Intranasal Insulin and Post-stroke Cognition: A Pilot Study

Condition:   Stroke
Interventions:   Drug: Intranasal Insulin;   Drug: Intranasal saline
Sponsor:   Wake Forest School of Medicine
Recruiting - verified June 2016

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Conditions:   Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified June 2016

Quality of Anticoagulation With Warfarin in Patient With Atrial Fibrillation for Secondary Stroke Prevention in Korea

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Inje University
Recruiting - verified June 2016

Efficacy and Safety Study to Evaluate Vadadustat for the Correction of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Conditions:   Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified June 2016

A Study of the ReCor Medical Paradise System in Clinical Hypertension

Conditions:   Hypertension;   Vascular Diseases
Interventions:   Device: The Paradise® Renal Denervation Ultrasound System;   Device: Sham Procedure
Sponsor:   ReCor Medical, Inc.
Recruiting - verified March 2016

GLP-1 and Hyperoxia for Organ Protection in Heart Surgery

Conditions:   Coronary Disease;   Shock, Cardiogenic;   Renal Failure;   Stroke;   Brain Injury;   Aortic Valve Disease
Interventions:   Drug: Byetta (Lilly, Exenatide);   Drug: Conoxia (AGA, oxygen);   Drug: 20% Human Albumin
Sponsor:   Rigshospitalet, Denmark
Recruiting - verified June 2016

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Testing a Community Intervention to Increase Aspirin Use

Conditions:   Myocardial Infarction;   Stroke
Interventions:   Other: Mass Media plus clinic intervention.;   Other: Media
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified June 2016

Cranial Temperature Early Diagnose Hemorrhagic and Ischemic Stroke

Conditions:   Ischemic Stroke;   Hemorrhagic Stroke
Intervention:  
Sponsor:   Third Military Medical University
Recruiting - verified June 2016

Natural History of Rett Syndrome & Related Disorders

Conditions:   Rett Syndrome;   MECP2 Duplication dIsorder;   RTT-related Conditions
Intervention:  
Sponsors:   University of Alabama at Birmingham;   National Institutes of Health (NIH);   National Center for Advancing Translational Science (NCATS);   Rare Diseases Clinical Research Network;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Patient Convenience Study

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Effects of Upper Extremity Rehabilitation Using Smart Glove in Stroke Patients

Conditions:   Stroke;   Hemiplegia
Intervention:   Device: Smart Glove Treatment
Sponsors:   Seoul National University Hospital;   SMG-SNU Boramae Medical Center
Recruiting - verified June 2016

Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke

Conditions:   Acute Ischemic Stroke;   Thrombotic Disease
Interventions:   Drug: DS-1040b;   Drug: placebo
Sponsor:   Daiichi Sankyo Inc.
Recruiting - verified June 2016

Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3

Conditions:   Stroke, Acute;   Cerebral Infarction
Interventions:   Procedure: Endovascular Thrombectomy;   Device: Trevo Retriever;   Device: Solitaire™ FR Revascularization Device;   Device: Penumbra thrombectomy system;   Device: Covidien MindFrame Capture Revascularization Device
Sponsors:   Gregory W Albers;   National Institute of Neurological Disorders and Stroke (NINDS);   University of Cincinnati;   Medical University of South Carolina;   NINDS Stroke Trials Network (StrokeNet)
Recruiting - verified June 2016

Effects of N-acetylcysteine on Cardiorespiratory Control in COPD Patients With Mild-to-moderate Airflow Obstruction

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: N-acetylcysteine;   Drug: Placebo
Sponsor:   Queen's University
Completed - verified June 2016

Safety of PZ-128 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention

Conditions:   Arterial Occlusive Diseases;   Coronary Artery Disease;   Coronary Disease;   Arteriosclerosis;   Heart Diseases;   Myocardial Ischemia;   Vascular Diseases;   Acute Coronary Syndrome
Interventions:   Drug: PZ-128;   Drug: Placebo
Sponsors:   Tufts Medical Center;   National Heart, Lung, and Blood Institute (NHLBI);   RTI International;   Inova Fairfax Hospital;   University of Massachusetts, Worcester
Recruiting - verified June 2016

Special Drug Use Investigation of Xarelto for Venous Thromboembolism (VTE)

Condition:   Venous Thromboembolism
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified June 2016

The Study to Reevaluate the Safety and Efficacy of Human Urinary Kallikrein

Condition:   Cerebral Infarction
Intervention:   Drug: kallikrein
Sponsor:   Techpool Bio-Pharma Co., Ltd.
Enrolling by invitation - verified June 2016

Targeted Electrotherapy for Aphasia Stroke Rehabilitation (TEASER) - Phase II Multi-Center Study

Condition:   Chronic Aphasia
Interventions:   Device: HD-tDCS (Soterix Medical, Active);   Device: HD-tDCS (Soterix Medical, Sham)
Sponsors:   Soterix Medical;   National Institute of Neurological Disorders and Stroke (NINDS);   Georgetown University;   University of North Carolina, Chapel Hill;   The City College of New York;   Medstar Research Institute;   University of South Carolina
Recruiting - verified June 2016

Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes

Condition:   Transcatheter Aortic Valve Replacement
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Acetylsalicylic acid;   Drug: Clopidogrel
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified June 2016

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified June 2016

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified June 2016

Anakinra, A Recombinant Human IL-1 Receptor Antagonist for Neuroinflammation in HIV-1 Infection

Conditions:   HIV Infections;   Neurologic Disorders
Intervention:   Drug: Anakinra
Sponsors:   National Institute of Neurological Disorders and Stroke (NINDS);   Johns Hopkins University
Recruiting - verified June 2016

Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS

Condition:   Acute Coronary Syndrome
Interventions:   Drug: dalcetrapib;   Drug: Placebo
Sponsors:   DalCor Pharmaceuticals;   The Montreal Health Innovations Coordinating Center (MHICC);   Medpace, Inc.;   Roche Molecular Systems, Inc
Recruiting - verified June 2016

Novel Treatment For Pusher Syndrome Using Physical Therapy

Condition:   Pusher Syndrome
Interventions:   Other: Novel physical therapy;   Other: Standard physical therapy
Sponsor:   Loma Linda University
Enrolling by invitation - verified June 2016

Tecarfarin Anti-Coagulation Trial (TACT)

Conditions:   Thromboembolism;   Thrombosis
Interventions:   Drug: Warfarin;   Drug: tecarfarin
Sponsor:   Armetheon Inc
Not yet recruiting - verified June 2016

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified June 2016

Novel Biomarkers of Thrombotic Risk

Condition:   Myocardial Infarction
Intervention:  
Sponsors:   University of Vermont;   Janssen Research & Development, LLC
Recruiting - verified June 2016

In Vivo Characterization of Inflammation With Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging

Condition:   Multiple Sclerosis
Intervention:   Drug: Ferumoxytol
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified March 2016

Speed of Processing Training in Traumatic Brain Injury

Conditions:   Traumatic Brain Injury;   Vascular Accident, Brain
Interventions:   Other: Brain Fitness Program;   Other: Weekly Telephone Contact
Sponsor:   New York University School of Medicine
Recruiting - verified June 2016

Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease

Conditions:   Irritable Mood;   Huntington's Disease
Interventions:   Drug: SRX246;   Drug: Placebo
Sponsors:   Azevan Pharmaceuticals;   National Institute of Neurological Disorders and Stroke (NINDS);   NeuroNEXT Network
Recruiting - verified June 2016

Aspirin Twice a Day in Patients With Diabetes and Acute Coronary Syndrome

Conditions:   Diabetes Mellitus;   Acute Coronary Syndrome;   Coronary Artery Disease
Interventions:   Drug: Novel strategy Aspirin;   Drug: Conventional strategy Aspirin
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Bayer
Recruiting - verified June 2016

Real Evidence of Anticoagulation Treatment in Non-valvular Atrial Fibrillation in Germany and the UK: REACT-AF2

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Bristol-Myers Squibb;   IMS Health;   Oxon Epidemiology
Active, not recruiting - verified June 2016

Unilateral vs. Bilateral Approaches to Hybrid Stroke Rehabilitation

Condition:   Stroke
Interventions:   Procedure: Unilateral Hybrid Intervention;   Procedure: Bilateral Hybrid Intervention;   Procedure: Robot-Assisted Training
Sponsor:   Chang Gung Memorial Hospital
Recruiting - verified April 2015

Coronary InterventionS in HIgh-Risk PatiEnts Using a Novel Percutaneous Left Ventricular Support Device (SHIELD II)

Condition:   Coronary Artery Disease
Interventions:   Device: HeartMate PHP;   Device: Abiomed Impella® Recover® LP 2.5
Sponsors:   Thoratec Corporation;   St. Jude Medical
Recruiting - verified June 2016

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion
Recruiting - verified June 2016

Oral Guanabenz for Multiple Sclerosis

Conditions:   Multiple Sclerosis, Relapsing-Remitting;   Multiple Sclerosis
Intervention:   Drug: Guanabenz
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Transcranial Direct Current Stimulation for Post-Stroke Aphasia

Condition:   Stroke
Interventions:   Behavioral: Aphasia therapy;   Device: Anodal tDCS;   Device: Sham tDCS
Sponsors:   Columbia University;   Pitkin Foundation
Terminated - verified June 2016

COcoa Supplement and Multivitamin Outcomes Study

Conditions:   Cardiovascular Disease;   Cancer
Interventions:   Dietary Supplement: Cocoa extract;   Dietary Supplement: Multivitamin;   Dietary Supplement: Cocoa extract placebo;   Dietary Supplement: Multivitamin placebo
Sponsors:   Brigham and Women's Hospital;   Fred Hutchinson Cancer Research Center;   Mars, Inc.;   Pfizer
Recruiting - verified June 2016

The Evaluation of Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of JPI-289 in Healthy Male Volunteers

Condition:   Stroke
Interventions:   Drug: JPI-289;   Drug: Placebo
Sponsor:   Jeil Pharmaceutical Co., Ltd.
Completed - verified March 2015

Renal Denervation Using the Vessix Renal Denervation System for the Treatment of Hypertension (REDUCE HTN:REINFORCE)

Condition:   Hypertension
Interventions:   Device: Renal Denervation (Vessix);   Device: Renal Angiography
Sponsor:   Boston Scientific Corporation
Recruiting - verified June 2016

The Bicuspid Aortic Stenosis Following Transcatheter Aortic Valve Replacement Registry

Conditions:   Aortic Valve Stenosis;   Cardiovascular Diseases;   Heart Valve Diseases;   Bicuspid
Intervention:   Procedure: transcatheter aortic valve replacement
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified June 2016

Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)

Conditions:   Vertigo;   Dizziness
Intervention:   Device: VRT Care
Sponsors:   Johns Hopkins University;   National Institute on Deafness and Other Communication Disorders (NIDCD);   GN Otometrics
Not yet recruiting - verified June 2016

Telerehabilitation in the Home Versus Therapy In-Clinic for Patients With Stroke

Condition:   Stroke
Interventions:   Device: Telerehabilitation Therapy;   Behavioral: In-Clinic Therapy
Sponsor:   University of California, Irvine
Recruiting - verified June 2016

Altering Activation Patterns Post-stroke

Conditions:   Stroke;   Muscle Spasticity;   Hemiparesis
Interventions:   Drug: Cyproheptadine;   Drug: Placebo for Cyproheptadine;   Other: Active Movement Practice (AMP);   Other: Passive Cyclical Stretching
Sponsors:   Rehabilitation Institute of Chicago;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified June 2016

Early Tracheostomy in Ventilated Stroke Patients 2

Condition:   Ischemic and Hemorrhagic Stroke, Subarachnoid Hemorrhage
Intervention:   Procedure: Tracheostomy
Sponsors:   University Hospital Heidelberg;   Maine Medical Center
Recruiting - verified June 2016

Managing Aftercare for Stroke (MAS): MAS-I - a Cross Sectional Study of Post-rehabilitation Stroke Burden and Patients' Needs

Condition:   Ischemic Stroke
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Prof. Dr. Ian Wellwood;   Prof. Dr. Jörg Wissel
Completed - verified June 2016

Comparative Study of Haemodynamic Changes After Spinal Anaesthesia in Non-obese and Pregnant Women

Condition:   Low Cardiac Output
Intervention:   Device: LiDCOrapid
Sponsor:   University of Aberdeen
Recruiting - verified June 2016

The Asian Transcatheter Aortic Valve Replacement Registry

Conditions:   Aortic Valve Stenosis;   Aortic Diseases
Intervention:   Device: transcatheter aortic valve replacement
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified June 2016

Serum Neuroglobin and HIF-1α in Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Intervention:  
Sponsor:   Shanghai 6th People's Hospital
Completed - verified June 2016

Sedation Depth in Neurocritical Care

Condition:   Sedation of Cerebrovascular Ventilated Critical Care Patients
Interventions:   Other: Intensive Care Sedation (depth, level);   Drug: Vasopressors to maintain normal blood pressure values, if needed;   Drug: Osmotherapeutics to lowr intracranial pressure, if needed;   Procedure: Endovascular stroke care to treat brain vessel occlusions, if needed;   Procedure: Decompressive neurosurgery, if needed
Sponsor:   Heidelberg University
Not yet recruiting - verified June 2016

Comparative Effectiveness of Rehabilitation Services for Survivors of Acute Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:   Other: retrospective analysis
Sponsors:   Duke University;   Patient-Centered Outcomes Research Institute
Active, not recruiting - verified September 2015

Safety and Effect of SANGUINATE™ Infusion in Patients at Risk of Delayed Cerebral Ischemia (DCI) Following Subarachnoid Hemorrhage (SAH)

Condition:   Cerebral Ischemia
Intervention:   Biological: SANGUINATE™
Sponsor:   Prolong Pharmaceuticals
Recruiting - verified June 2016

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified June 2016

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability

Conditions:   Chronic Troublesome Sialorrhea;   Cerebral Palsy;   Stroke;   Traumatic Brain Injury;   Intellectual Disability
Interventions:   Drug: IncobotulinumtoxinA;   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Recruiting - verified June 2016

Acupuncture for Cerebral Vasospasm After Subarachnoid Hemorrhage

Conditions:   SAH (Subarachnoid Hemorrhage);   Cerebral Vasospasm
Interventions:   Device: acupuncture;   Device: Electroacupuncture;   Device: Intradermal acupuncture;   Device: Mock transcutaneous electrical nerve stimulation;   Device: sham intradermal acupuncture
Sponsor:   Kyung Hee University Hospital at Gangdong
Recruiting - verified June 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified June 2016

Hispanic Secondary Stroke Prevention Initiative

Condition:   Stroke
Interventions:   Behavioral: Community Health Worker (CHW) home visits, coaching phone calls, group sessions .;   Other: usual care and health education brochures every 4 months.
Sponsors:   University of Miami;   National Institute on Minority Health and Health Disparities (NIMHD)
Recruiting - verified June 2016

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:   Device: Reveal LINQ Insertable Cardiac Monitor
Sponsor:   Northwell Health
Recruiting - verified June 2016

Left-Atrium-Appendage Occluder Register - GErmany

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Stiftung Institut fuer Herzinfarktforschung
Active, not recruiting - verified June 2016

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Atrial Fibrillation Detected by ELR and Holter Recording, a Comparison in Patients With Ischemic Stroke or TIA

Conditions:   Stroke;   Ischaemic Stroke;   Atrial Fibrillation;   Supra Ventricular Extra Systoles
Intervention:  
Sponsors:   University of Aarhus;   Hospitalsenheden Vest
Recruiting - verified June 2016

DLBS1033 for Acute Ischemic Stroke Patients

Conditions:   Acute Ischemic Stroke;   Partial Anterior Circulation Infarct;   Lacunar Anterior Circulation Infarct
Interventions:   Drug: DLBS1033;   Drug: Placebo
Sponsor:   Dexa Medica Group
Recruiting - verified June 2016

Comparative Evaluation of IRM and Autopsy in the Evaluation of Intra Uterine Fetal Death

Condition:   Spontaneous Intra Uterine Fetal Death
Intervention:   Other: Comparaison between MR and autopsy in the macroscopic evaluation of intra uterine death.
Sponsor:   University Hospital, Rouen
Recruiting - verified June 2016

Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia

Condition:   Critical Limb Ischemia
Interventions:   Genetic: HGF Plasmid (AMG0001);   Genetic: Matching Placebo
Sponsor:   AnGes
Terminated - verified June 2016

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Losmapimod 7.5 mg twice daily;   Drug: Placebo twice daily;   Drug: Standard therapy
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Completed - verified June 2016

Comparison of the Functional Walking Outcomes of Two Settings of a Commercially Available Ankle Foot Orthosis in Adult Stroke Patients

Condition:   Walking Aided by a Leg Brace in Stroke Subjects
Interventions:   Device: ADR™-based brace resistance (Adjustable Dynamic Response™);   Device: Conventional brace resistance (using hard stops)
Sponsor:   Albert Einstein Healthcare Network
Active, not recruiting - verified June 2016

Rehabilitating Corticospinal Control of Walking

Condition:   Stroke
Interventions:   Behavioral: ACC training;   Behavioral: SS training
Sponsors:   VA Office of Research and Development;   University of Florida;   Brooks Center for Rehabilitation Studies
Recruiting - verified June 2016

Pilot Investigation of Stem Cells in Stroke Phase II Efficacy

Conditions:   Ischaemic Stroke;   Cerebral Infarction;   Hemiparesis;   Arm Paralysis
Intervention:   Biological: CTX DP
Sponsor:   ReNeuron Limited
Recruiting - verified June 2016

Carnitine for the Treatment of Atherosclerosis.

Condition:   Metabolic Syndrome
Interventions:   Dietary Supplement: L-carnitine capsules;   Dietary Supplement: Cellulose capsules
Sponsors:   Queen's University;   Heart and Stroke Foundation of Canada
Recruiting - verified June 2016

A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients

Conditions:   Heart Failure;   Respiratory Insufficiency;   Stroke Acute;   Infectious Diseases;   Rheumatic Diseases
Interventions:   Drug: Rivaroxaban, 10 mg;   Drug: Rivaroxaban, 7.5 mg;   Drug: Placebo
Sponsor:   Janssen Research & Development, LLC
Recruiting - verified June 2016

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Condition:   Carotid Stenosis
Interventions:   Procedure: Carotid endarterectomy;   Device: Carotid stenting
Sponsors:   Thomas G. Brott, M.D.;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions

Conditions:   Chronic Troublesome Sialorrhea;   Parkinson's Disease;   Post-stroke;   Traumatic Brain Injury
Interventions:   Drug: IncobotulinumtoxinA (100 Units);   Drug: IncobotulinumtoxinA (75 Units);   Drug: Placebo
Sponsor:   Merz Pharmaceuticals GmbH
Active, not recruiting - verified June 2016

Safety and Efficacy of Ticagrelor Versus Clopidogrel in Asian/KOREAn Patients With Acute Coronary Syndromes Intended for Invasive Management

Conditions:   Acute Coronary Syndrome;   Myocardial Ischemia;   Heart Diseases;   Cardiovascular Diseases;   Angina Pectoris
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified June 2016

Phase ⅡStudy of Pinocembrin Injection to Treat Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:   Drug: Pinocembrin for Injection
Sponsor:   CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Suspended - verified October 2015

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)

Conditions:   Hypertension;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified June 2016

Asan Multivessel Registry

Condition:   Coronary Artery Disease
Intervention:   Other: Treatment
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified June 2016

Cardiovascular Outcomes Following Ertugliflozin Treatment in Type 2 Diabetes Mellitus Participants With Vascular Disease, The VERTIS CV Study (MK-8835-004)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Recruiting - verified June 2016

The Evaluation of Safety, Tolerability and Pharmacokinetics of Stroke Targeting Drug in Healthy Volunteers

Condition:   Stroke
Interventions:   Drug: JPI-289;   Other: Placebo
Sponsor:   Jeil Pharmaceutical Co., Ltd.
Completed - verified September 2014

Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer

Conditions:   Rivaroxaban;   Cancer-associated Thrombosis;   Recurrence;   Bleeding
Intervention:   Drug: Rivaroxaban
Sponsors:   Seoul National University Hospital;   Korean Society of Hematology Thrombosis Working Party
Active, not recruiting - verified June 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified June 2016

Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions

Condition:   Healthy Volunteers
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Active, not recruiting - verified June 2016

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified June 2016

Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation

Condition:   End Stage Heart Disease
Intervention:   Device: Early VAD implantation
Sponsors:   German Heart Institute;   Deutsches Zentrum für Herz-Kreislauf-Forschung;   Helmholtz Zentrum München;   Universitätsmedizin Greifswald;   Universitätsmedizin Göttingen
Recruiting - verified June 2016

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified June 2016

Self-Management in Stroke Survivors

Conditions:   Stroke;   Hypertension
Intervention:   Other: Self-Management / MTM using Health IT
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Berman Center for Outcomes and Clinical Research;   Agency for Healthcare Research and Quality (AHRQ)
Completed - verified June 2016

Long-Term rIsk, Clinical manaGement and Healthcare Resource Utilization of Stable CAD in Post MI Patients

Condition:   Stable Coronary Artery Disease (CAD), Myocardial Infarction
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified June 2016

Pediatric Autologous Bone Marrow Mononuclear Cells for Severe Traumatic Brain Injury

Condition:   Traumatic Brain Injury
Interventions:   Biological: autologous bone marrow mononuclear cells;   Other: Placebo Infusion
Sponsors:   The University of Texas Health Science Center, Houston;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Anticoagulant Utilization Pattern

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery

Conditions:   High Risk Non-cardiac Surgery;   Death;   Delirium;   Kidney Injury;   Myocardial Infarction;   Respiratory Failure;   Postoperative Infection
Intervention:   Other: Observational study
Sponsors:   University of Manitoba;   Canadian Anesthesia Research Foundation
Recruiting - verified June 2016

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Active, not recruiting - verified June 2016

Vestibular Rehabilitation for Strokepatients With Dizziness

Conditions:   Stroke;   Dizziness
Intervention:   Other: Vestibular rehabilitation
Sponsors:   Lund University;   Region Skåne, Primary health care, Sweden
Recruiting - verified June 2016

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa (Dabigatran etexilate mesilate)
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Asia

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Completed - verified June 2016

Study Comparing Ticagrelor With Aspirin for Prevention of Vascular Events in Patients Undergoing CABG

Conditions:   Coronary Artery Disease;   Stable Angina;   Acute Coronary Syndrome
Interventions:   Drug: Ticagrelor;   Drug: Aspirin;   Drug: Placebo - Ticagrelor;   Drug: Placebo - Aspirin
Sponsors:   Deutsches Herzzentrum Muenchen;   AstraZeneca
Recruiting - verified June 2016

Multicenter Trial to Evaluate the Effect of Dapagliflozin on the Incidence of Cardiovascular Events

Conditions:   Diabetes Mellitus, Non-Insulin-Dependent;   High Risk for Cardiovascular Event
Interventions:   Drug: Dapagliflozin 10 mg;   Drug: Placebo tablet
Sponsors:   AstraZeneca;   Bristol-Myers Squibb;   The TIMI Study Group;   Hadassah Medical Organization
Active, not recruiting - verified June 2016

Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

Condition:   Progressive Multifocal Leukoencephalopathy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Stroke Prevention and Rhythm Interventions in Atrial Fibrillation

Condition:   Cardiovascular Diseases
Intervention:  
Sponsors:   Canadian Cardiovascular Research Network;   Bayer
Active, not recruiting - verified June 2016

Evaluation of the Phased Radio Frequency Ablation System

Condition:   Persistent Atrial Fibrillation
Intervention:   Device: Medtronic Phased RF Ablation System
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified June 2016

A Study of Evacetrapib in High-Risk Vascular Disease

Condition:   Cardiovascular Diseases
Interventions:   Drug: Evacetrapib;   Drug: Placebo
Sponsors:   Eli Lilly and Company;   The Cleveland Clinic
Active, not recruiting - verified June 2016

Brain Stimulation and Aphasia Treatment

Condition:   Aphasia
Interventions:   Device: Activa Dose II Real tDCS;   Device: Activa Dose II Sham tDCS
Sponsors:   University of South Carolina;   National Institute on Deafness and Other Communication Disorders (NIDCD);   Medical University of South Carolina
Recruiting - verified June 2016

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: Placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified June 2016

The Efficacy and Economics of Exercise Maintenance Post-Cardiac Rehabilitation

Condition:   Coronary Artery Disease
Intervention:   Behavioral: Exercise Facilitator Intervention
Sponsors:   Ottawa Heart Institute Research Corporation;   Heart and Stroke Foundation of Ontario
Recruiting - verified June 2016

Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility

Condition:   Multiple Sclerosis
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Xarelto [SPAF-QOL] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban (Xarelto_ BAY59-7939)
Sponsor:   Bayer
Active, not recruiting - verified June 2016

Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome

Conditions:   Klinefelter Syndrome;   XXY Syndrome
Interventions:   Drug: Testosterone gel 1%;   Drug: Placebo gel
Sponsors:   University of Colorado, Denver;   Colorado Clinical & Translational Sciences Institute;   Children's Hospital Colorado;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Botulinum Toxin for Pelvic Pain in Women With Endometriosis

Conditions:   Endometriosis;   Botulinum Toxin A;   Chronic Pelvic Pain;   Pelvic Muscle Spasms;   Quality of Life
Intervention:   Drug: Botuninum toxin A
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Imaging Biomarkers in Parkinson s Disease

Condition:   Parkinson Disease
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Study in Parkinson's Disease of Exercise

Condition:   Parkinson Disease
Interventions:   Behavioral: Moderate Exercise;   Behavioral: Vigorous Exercise;   Behavioral: No Intervention
Sponsors:   University of Colorado, Denver;   University of Illinois at Chicago;   University of Pittsburgh;   Rush University Medical Center;   National Institute of Neurological Disorders and Stroke (NINDS);   Northwestern University
Active, not recruiting - verified June 2016

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Recruiting - verified June 2016

Bazedoxifene Post Approval Safety Study (PASS) in the European Union (EU)

Condition:   Osteoporosis, Postmenopausal
Interventions:   Drug: Bazedoxifene;   Drug: Bisphosphonate;   Drug: Raloxifene
Sponsor:   Pfizer
Active, not recruiting - verified June 2016

Non-invasive Brain Stimulation for People With Stroke

Condition:   Stroke
Intervention:   Device: Robot therapy and transcranial direct current stimulation
Sponsors:   University of Southampton;   University College, London
Completed - verified June 2016

"Spot Sign" Selection of Intracerebral Hemorrhage to Guide Hemostatic Therapy

Condition:   Stroke
Interventions:   Biological: rfVIIa;   Other: Standard saline solution
Sponsors:   Dr. David Gladstone;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified June 2016

Effectiveness of Clopidogrel Resinate in PCI(PRIDE)

Condition:   Coronary Artery Disease
Interventions:   Drug: Pregrel®;   Drug: Plavix®
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Active, not recruiting - verified June 2016

Early Thienopyridine Treatment to Improve Primary PCI in Patients With Acute MI

Conditions:   Myocardial Infarction;   STEMI
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel
Sponsors:   Stiftung Institut fuer Herzinfarktforschung;   Daiichi Sankyo Inc.
Completed - verified June 2016

Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People With Multiple Sclerosis

Conditions:   Multiple Sclerosis;   Optic Neuritis
Intervention:   Drug: Mangafodipir (Teslascan)
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

CAROLINA: Cardiovascular Outcome Study of Linagliptin Versus Glimepiride in Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: linagliptin;   Drug: glimepiride;   Drug: linagliptin placebo;   Drug: glimepride placebo
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Active, not recruiting - verified June 2016

Living With Aphasia: An International Study

Condition:   Aphasia
Intervention:  
Sponsors:   New York University School of Medicine;   The Solomon Foundation;   The University of Queensland
Terminated - verified June 2016

Effects of Rapid-Resisted Exercise and Bright Light Therapy on Ambulatory Adults With Traumatic Brain Injury

Conditions:   Adult;   Traumatic Brain Injury;   fMRI
Interventions:   Other: Exercise;   Other: Mood Therapy
Sponsors:   National Institutes of Health Clinical Center (CC);   Center for Neuroscience and Regenerative Medicine (CNRM);   Henry M. Jackson Foundation for the Advancement of Military Medicine;   United States Department of Defense
Completed - verified June 2016

German Ablation Quality-Register

Condition:   Arrhythmia
Intervention:  
Sponsor:   Stiftung Institut fuer Herzinfarktforschung
Completed - verified June 2016

Drug-Eluting Stent Implantation Versus Optimal Medical Treatment in Patients With Chronic Total Occlusion (DECISION-CTO)

Condition:   Coronary Artery Disease
Interventions:   Procedure: Cypher, xience, Endeavor, Taxus;   Drug: optimal medical therapy
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified June 2016

Physiological Investigations of Movement Disorders

Conditions:   Parkinson's Disease;   Tourette's Syndrome;   Tic Disorders;   Dystonia;   Movement Disorders
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Genetics of Spina Bifida and Anencephaly

Conditions:   Anencephaly;   Acrania
Intervention:  
Sponsors:   Duke University;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Effects of Tolcapone on Frontotemporal Dementia

Condition:   Frontotemporal Lobar Degeneration
Interventions:   Drug: Tolcapone;   Drug: Placebo
Sponsors:   Columbia University;   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified June 2016

Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence

Conditions:   Ischemic Stroke;   Patent Foramen Ovale;   Atrial Septal Aneurysm;   Migraine
Interventions:   Drug: aspirin;   Drug: Antivitamins K or rivaroxaban or dabigatran or apixaban;   Device: Devices for PFO closure
Sponsor:   Assistance Publique - Hôpitaux de Paris
Active, not recruiting - verified June 2016

Efficacy of Implantable Cardioverter Defibrillator in Patients With Non-ischemic Systolic Heart Failure on Mortality

Conditions:   Heart Failure;   Dilated Cardiomyopathy;   Reduced LVEF
Interventions:   Device: ICD;   Other: Optimal medical treatment
Sponsors:   Danish Study Group;   Danish Heart Foundation
Active, not recruiting - verified June 2016

Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System

Condition:   Healthy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016

Assessment of Noninvasive Methods to Identify Patients at Risk of Serious Arrhythmias After a Heart Attack

Conditions:   Myocardial Infarction;   Death, Sudden, Cardiac;   Death
Interventions:   Procedure: Spectral T Wave Alternans;   Procedure: Modified Moving Average T Wave Alternans;   Procedure: Baroreceptor Sensitivity;   Procedure: Heart Rate Variability;   Procedure: Heart Rate Turbulence;   Procedure: Deceleration Capacity;   Procedure: Signal Averaged ECG
Sponsors:   University of Calgary;   Canadian Institutes of Health Research (CIHR);   Heart and Stroke Foundation of Canada;   Alberta Heritage Foundation for Medical Research;   GE Healthcare;   Cambridge Heart Inc.;   Hoffmann-La Roche
Completed - verified November 2006

Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo

Condition:   Epilepsies, Partial
Interventions:   Drug: Lyrica (pregabalin);   Drug: placebo
Sponsor:   Pfizer
Recruiting - verified June 2016

The Metabolic Effects of Almond Consumption in Adults With Pre-Diabetes

Conditions:   Prediabetes;   Insulin Resistance;   Metabolic Syndrome
Interventions:   Behavioral: Almonds in a calorie controlled diet;   Behavioral: Nut free diet
Sponsors:   University of Medicine and Dentistry of New Jersey;   Almond Board of California
Completed - verified June 2016

Neurobiological Predictors of Huntington's Disease (PREDICT-HD)

Condition:   Huntington Disease
Intervention:  
Sponsors:   University of Iowa;   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified June 2016

Evaluation and Treatment of Patients With Epilepsy

Condition:   Epilepsy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2016