Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Direction Modulation of Muscle Synergies After a Stroke

Conditions:   Stroke;   Motor Disorders
Intervention:   Diagnostic Test: Surface Electromyography (EMG)
Sponsor:   University of Haifa
Recruiting - verified February 2017

Clinical Trial to Evaluate the Efficacy and Safety of JPI-289 in Patients With Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: JPI-289 Low-dose;   Drug: JPI-289 High-dose;   Drug: Placebo
Sponsor:   Jeil Pharmaceutical Co., Ltd.
Recruiting - verified June 2016

Sensorimotor Retraining in Chronic Stroke

Condition:   Stroke
Interventions:   Other: Sensorimotor retraining;   Other: Relaxation technique
Sponsor:   University of Valencia
Recruiting - verified February 2017

Contralaterally Controlled Functional Electrical Stimulation Plus Video Games for Hand Therapy After Stroke

Conditions:   Upper Extremity Hemipelegia;   Stroke
Intervention:   Device: Neuromuscular electrical stimulation (NMES)
Sponsor:   VA Office of Research and Development
Not yet recruiting - verified February 2017

In Home VR Therapy

Condition:   Stroke
Interventions:   Other: Single-User Virtual Reality Upper Extremity Therapy;   Other: Multi-User Virtual Reality Upper Extremity Therapy
Sponsor:   Rehabilitation Institute of Chicago
Recruiting - verified February 2017

Lycra Orthosis as Therapy for the Upper Limb After Stroke

Conditions:   Stroke;   Cerebrovascular Accident
Interventions:   Device: Dynamic Lycra Orthosis;   Other: Usual Rehabilitation
Sponsors:   Glasgow Caledonian University;   University of Dundee;   Chief Scientist Office of the Scottish Government
Recruiting - verified February 2017

Patient Perceptions and Physician Assessment of Benefits and Risks of Oral Anticoagulation Due to Non-valvular Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Health Literacy
Intervention:   Other: Questionnaire
Sponsor:   Medical University of Graz
Active, not recruiting - verified February 2017

Exercise and Brain Stimulation for Post-stroke Depression

Condition:   Stroke
Interventions:   Behavioral: Aerobic exercise;   Other: Repetitive transcranial magnetic stimulation
Sponsor:   Medical University of South Carolina
Recruiting - verified February 2017

Optimal Antithrombotic Therapy in Ischemic Stroke Patients With Non-Valvular Atrial Fibrillation and Atherothrombosis

Conditions:   Ischemic Stroke;   Atrial Fibrillation;   Atherothrombosis
Interventions:   Drug: Oral Anticoagulant;   Drug: Antiplatelet Drug
Sponsors:   National Cerebral and Cardiovascular Center;   Network for Clinical Stroke Trials;   The BMS/Pfizer Japan Thrombosis Investigator Initiated Research Program
Not yet recruiting - verified February 2017

Evaluating the Indego Exoskeleton for Persons With Hemiplegia Due to CVA

Conditions:   Cerebrovascular Accident (CVA);   Stroke;   Hemiplegia
Intervention:   Device: Indego Exoskeleton
Sponsors:   Parker Hannifin Corporation;   Shepherd Center, Atlanta GA;   Cedars-Sinai Medical Center;   Sheltering Arms Physical Rehabilitation Hospitals;   Rehabilitation Institute of Chicago;   Kessler Foundation;   St. Charles Hospital;   TIRR Memorial Hermann;   Rusk Rehabilitation
Recruiting - verified February 2017

Low-dose of Ticagrelor and Double Standard-dose Clopidogrel on Platelet Aggregation in Clopidogrel Resistance's Patients With Coronary Heart Disease

Conditions:   Coronary Artery Disease;   Clopidogrel, Poor Metabolism of
Interventions:   Drug: Clopidogrel;   Drug: ticagrelor
Sponsor:   First Affiliated Hospital of Harbin Medical University
Recruiting - verified February 2017

The Applying of Acupressure and Abdominal Massage to Improving Constipation in Stroke Patients.

Conditions:   Acupressure;   Abdominal Massage;   Constipation;   Stroke Patients
Interventions:   Other: Acupressure and Abdominal Massage;   Other: Pressing the Sham points
Sponsor:   Li-Li Chen
Enrolling by invitation - verified February 2017

Use of a Mini-fluid Bolus to Identify Fluid Responsiveness

Conditions:   Cardiac Output, Low;   Cardiac Output, High
Interventions:   Procedure: Small fluid boluses of 50 ml;   Device: LIDCORapid Monitor
Sponsor:   The Royal Wolverhampton Hospitals NHS Trust
Not yet recruiting - verified February 2017

Outcomes in UK ACS Patients Prescribed Ticagrelor

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Completed - verified February 2017

SpecTRA; An Observational Study of the Verification of Protein Biomarkers in Transient Ischemic Attack.

Condition:   TIA
Intervention:   Other: Non-Interventional Study
Sponsors:   Andrew Penn;   Genome Canada;   Genome British Columbia;   Genome Alberta;   Heart and Stroke Foundation of Canada;   Stroke Services BC;   Bruker Daltonics;   LifeLabs
Completed - verified February 2017

Ablation of Atrial Fibrillation in Heart Failure Patients

Conditions:   Atrial Fibrillation;   Severe Heart Failure
Intervention:   Procedure: Cryoablation
Sponsors:   Medical University of Silesia;   Military Institute of Medicine, Warsaw, Poland;   Clinical Hospital No. 2 Pomeranian Medical University, Szczecin, Poland;   Hospital name Pope John Paul, Zamosc, Poland
Recruiting - verified February 2017

Ferric Citrate in ESRD Pilot Project

Conditions:   End Stage Renal Disease;   Chronic Kidney Diseases
Intervention:   Drug: Ferric Citrate
Sponsors:   Sreedhar Mandayam;   Keryx Biopharmaceuticals
Recruiting - verified February 2017

Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation

Conditions:   Dementia;   Cognition Disorders;   Cerebral Ischemic Events
Interventions:   Drug: Dabigatran Etexilate;   Drug: Warfarin
Sponsors:   Intermountain Health Care, Inc.;   Boehringer Ingelheim
Not yet recruiting - verified January 2017

Acetylsalicylic Acid Plus Intensive Blood Pressure Treatment in Patients With Unruptured Intracranial Aneurysms

Condition:   Unruptured Intracranial Aneurysms
Interventions:   Drug: Acetylsalicylic acid;   Other: intensive blood pressure control
Sponsors:   Universitätsmedizin Mannheim;   UMC Utrecht;   Schwiete Stiftung, Mannheim, Germany;   KKS Netzwerk;   University of Hamburg
Not yet recruiting - verified February 2017

Colchicine and Spironolactone in Patients With STEMI / SYNERGY Stent Registry

Condition:   ST Elevation Myocardial Infarction
Interventions:   Drug: Colchicine;   Drug: Spironolactone;   Device: SYNERGY Bioabsorbable Polymer Drug-Eluting Stent;   Drug: Colchicine-Placebo;   Drug: Spironolactone-Placebo
Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research (CIHR);   Boston Scientific Corporation
Not yet recruiting - verified February 2017

Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training

Conditions:   Complete Spinal Cord Injury;   Incomplete Spinal Cord Injury;   Acquired Brain Injury;   Multiple Sclerosis
Interventions:   Device: ReWalk;   Device: EKSO;   Device: REX
Sponsor:   The University of Texas Health Science Center, Houston
Recruiting - verified February 2017

Revascularization in Patients Undergoing Transcatheter Aortic Valve Implantation

Conditions:   Coronary Artery Disease;   Aortic Valve Stenosis;   TAVI;   PCI
Intervention:   Procedure: PCI
Sponsors:   Rigshospitalet, Denmark;   Aarhus University Hospital;   Aalborg Universitetshospital;   Odense University Hospital;   Lund University Hospital;   Karolinska University Hospital;   Rikshospitalet University Hospital;   Haukeland University Hospital;   Helsinki University Central Hospital;   Tampere University Hospital;   Oulu University Hospital
Not yet recruiting - verified February 2017

Treatment Development of Triheptanoin (G1D)

Conditions:   Epilepsy;   GLUT1DS1;   Glut1 Deficiency Syndrome 1, Autosomal Recessive;   Glucose Metabolism Disorders;   Glucose Transport Defect;   Glucose Transporter Type 1 Deficiency Syndrome;   Glucose Transporter Protein Type 1 Deficiency Syndrome
Intervention:   Drug: Triheptanoin
Sponsors:   University of Texas Southwestern Medical Center;   National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - verified February 2017

Synchronous rTMS and Computer-integrated Speech Training Applied in Aphasic Patients and the Neuroimaging Study

Conditions:   Stroke;   Aphasia
Interventions:   Device: repetitive transcranial magnetic stimulation (rTMS);   Device: Sham stimulation;   Behavioral: Computer-integrated Speech Training
Sponsor:   Taipei Veterans General Hospital, Taiwan
Recruiting - verified January 2017

Platelet Acetyl Coenzyme A Carboxylase Phosphorylation in Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome;   Coronary Thrombosis
Intervention:   Diagnostic Test: Platelet Acetyl Coenzyme A Carboxylase analysis in CAD
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Completed - verified February 2017

Assessment of the St Jude Medical Portico Resheathable Aortic Valve System-Alternative Access

Condition:   Aortic Valve Stenosis
Intervention:   Device: TAVI
Sponsor:   St. Jude Medical
Not yet recruiting - verified February 2017

Effect of Exercise on Selected Anthropometric,Biochemical and Physiological Variables Among Hypertensive Patients

Condition:   Hypertension
Interventions:   Other: Aerobic exercise .;   Other: Resistance exercise;   Other: Aerobic and resistance exercise
Sponsor:   Mekelle University
Recruiting - verified February 2017

Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies

Condition:   Pyruvate Dehydrogenase Complex Deficiency Disease
Intervention:   Other: No intervention
Sponsors:   University Hospitals Cleveland Medical Center;   Rare Diseases Clinical Research Network;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2017

Remote Ischemic Preconditioning for Cardic Surgery

Conditions:   Myocardial Injury;   Remote Ischemic Preconditioning
Interventions:   Procedure: Remote Ischemic Preconditioning;   Procedure: Control
Sponsor:   Xuzhou Medical University
Recruiting - verified January 2017

Safety and Efficacy of the Symetis ACURATE Neo/TF Compared to the Edwards SAPIEN 3 Bioprosthesis.

Condition:   Aortic Valve Stenosis
Interventions:   Device: Symetis ACURATE neo/TF transfemoral TAVI system;   Device: Edwards Sapien 3 Transcatheter Heart Valve
Sponsors:   University Hospital Inselspital, Berne;   Kerckhoff Heart Center
Recruiting - verified February 2017

Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke

Conditions:   Stroke;   Stroke, Acute;   Brain Injury, Acute
Interventions:   Biological: Umbilical Cord Blood;   Other: Placebo
Sponsors:   Joanne Kurtzberg, MD;   The Marcus Foundation;   Emory University;   M.D. Anderson Cancer Center
Recruiting - verified February 2017

Acupuncture Treatment on Motor Dysfunction in Stroke Patients

Conditions:   Stroke;   Motor Disorders
Interventions:   Other: Acupuncture Treatment;   Other: Rehabilitation Treatment
Sponsors:   Shanghai University of Traditional Chinese Medicine;   Fudan University
Recruiting - verified November 2016

TCM Clinical Practice Rehabilitation of Post-stroke Spasticity

Condition:   Stroke
Interventions:   Other: Modern rehabilitation treatment;   Other: Modern rehabilitation &TCM;   Other: modern rehabilitation &Baimai Ruangao;   Other: modern rehabilitation &Tibetan medicine
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified February 2017

TIMING of Oral Anticoagulant Therapy in Acute Ischemic Stroke With Atrial Fibrillation

Conditions:   Ischemic Stroke;   Atrial Fibrillation
Interventions:   Other: Early start of NOAC;   Other: Late start of NOAC
Sponsors:   Uppsala University;   The Swedish Stroke Register (Riksstroke)
Recruiting - verified February 2017

Radiation Dose Optimization in Diffuse Large B- Cell Lymphoma.

Condition:   NonHodgkin Lymphoma
Interventions:   Radiation: Standard Arm;   Radiation: Experimental Arm
Sponsor:   Tata Memorial Hospital
Recruiting - verified February 2017

Remediation of the Non-Paretic Arm in Stroke

Condition:   Stroke
Interventions:   Behavioral: Track 1;   Behavioral: Track 2
Sponsor:   Milton S. Hershey Medical Center
Recruiting - verified February 2017

Automated Physician Notifications to Improve Guideline-Based Anticoagulation in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Other: Baseline alert
Sponsors:   Massachusetts General Hospital;   Boehringer Ingelheim
Active, not recruiting - verified February 2017

Safety and Efficacy of Alteplase When Administered in Chinese Patients With Acute Ischemic Hemispheric Stroke Where Thrombolysis is Initiated Between 3 and 4.5 Hours After Stroke Onset

Condition:   Stroke
Intervention:   Drug: alteplase
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

Whole Brain Vessel Wall Imaging in Stroke Patients (WISP): An International Multi-Center Registry

Condition:   Stroke
Intervention:   Device: MRI
Sponsor:   Cedars-Sinai Medical Center
Enrolling by invitation - verified February 2017

Sleep Apnoea in Haemodialysis

Conditions:   Sleep Apnoea;   Renal Failure;   End Stage Kidney Disease;   Sleep Disturbance;   Sleep Disorders;   Sleep
Interventions:   Procedure: Haemodiafiltration post-dilution model;   Procedure: Haemodialysis
Sponsors:   John Hunter Hospital;   Newcastle University;   Hunter Medical Research Institute
Recruiting - verified February 2017

Subcutaneous Median Nerve Neuromodulation For Drug-Treatment Resistant Hypertension.

Condition:   Resistant Hypertension
Intervention:   Device: eCoin System
Sponsor:   Valencia Technologies Corporation
Withdrawn - verified February 2017

Long Term Assessment of Post Thrombotic Syndrome : OPTIMEV Study ( SPOT )

Conditions:   Post Thrombotic Syndrome;   Venous Thromboembolism;   Cardiovascular Diseases
Interventions:   Other: Villalta phone score > or = to 5;   Other: Villalta phone score < 5
Sponsors:   Association des Médecins Vasculaires Hospitaliers;   Daiichi Sankyo Inc.;   Ministry of Health, France;   LEO Pharma;   Sanofi;   University Hospital, Grenoble
Not yet recruiting - verified February 2017

AMPLATZER™ Amulet™ LAA Occluder Trial

Condition:   Stroke
Interventions:   Device: Amulet Left Atrial Appendage Occluder;   Device: WATCHMAN Left Atrial Appendage Closure
Sponsor:   St. Jude Medical
Recruiting - verified February 2017

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Dialysis-dependent Chronic Kidney Disease (DD-CKD)

Condition:   Anemia in Subjects With DD-CKD
Interventions:   Drug: vadadustat;   Drug: darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified February 2017

Benefit-Risk Of Arterial THrombotic prEvention With Rivaroxaban for Atrial Fibrillation in France

Condition:   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Vitamin K antagonists;   Drug: dabigatran (Pradaxa)
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist

Condition:   Intracerebral Hemorrhage
Interventions:   Drug: Tranexamic acid;   Drug: Saline 0.9%
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation
Recruiting - verified February 2017

Efficacy and Safety Study to Evaluate Vadadustat for the Correction of Anemia in Subjects With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD)

Conditions:   Anemia;   Dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: Darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified February 2017

Acupuncture Lowering Blood Pressure for Secondary Prevention of Stroke

Condition:   Cerebral Infarction
Intervention:   Device: acupuncture
Sponsors:   First Teaching Hospital of Tianjin University of Traditional Chinese Medicine;   State Administration of Traditional Chinese Medicine of the People's Republic of China
Recruiting - verified February 2017

Abnormal Ventilatory Response to Carbon Dioxide: a Potential Biomarker for Seizure Induced Respiratory Depression & Modification by SSRI

Conditions:   Epilepsy;   SUDEP
Interventions:   Drug: Fluoxetine;   Drug: Placebo
Sponsor:   University of Iowa
Recruiting - verified February 2017

Evaluation of Diagnostic Criteria for Chronic Critical Limb Ischemia

Condition:   Stroke
Intervention:   Other: No intervention
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Completed - verified July 2016

Analysis of the Impact of the Fragility of the Over 70 Years of TIAprognosis

Conditions:   Vascular;   Stoke;   Ischemic;   Transient Ischemic Attack
Intervention:   Other: No intervention
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Recruiting - verified July 2016

The SMARTChip Stroke Study

Condition:   Stroke
Intervention:  
Sponsor:   University Hospitals Coventry and Warwickshire NHS Trust
Recruiting - verified February 2017

Treatment Convenience in Patients Treated With Dabigatran for Stroke Prophylaxis in Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

Comparison of the Hemodynamic Safety of Two Common Alveolar Recruitment Manoeuvres With Regard to Cardiac Output in a Surgical Intensive Care Unit

Condition:   Positive-Pressure Respiration
Interventions:   Device: echocardiography;   Device: Arterial oximetry
Sponsor:   Centre Hospitalier Universitaire, Amiens
Completed - verified February 2017

Perioperative Antiplatelet Therapy in Patients With Drug-eluting Stent Undergoing Noncardiac Surgery

Condition:   Antiplatelet Drugs
Interventions:   Drug: Aspirin only;   Drug: No antiplatelet therapy
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified February 2017

Observational Study to Evaluate Safety of Idarucizumab in Pediatric Patients

Conditions:   Uncontrolled Hemorrhage;   Emergency Procedures
Intervention:   Drug: idarucizumab
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified February 2017

Longitudinal Monitoring of Cerebral Connectivity 3T MRI in Patients With a Transcient Global Amnesia

Condition:   Amnesia
Interventions:   Procedure: achieving a neuropsychological examination in the acute amnesic phase;   Procedure: Neurological consultation with neuropsychological evaluation;   Radiation: MRI
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Recruiting - verified June 2016

Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques

Condition:   Multiple Sclerosis
Interventions:   Drug: Methylprednisolone;   Drug: Methylprednisolone
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified October 12, 2016

Links Between Depression, Anxiety, Coping and Quality of Life After a Stroke

Condition:   Cerebral Stroke
Intervention:   Other: survey
Sponsors:   Groupe Hospitalier Paris Saint Joseph;   University of Paris 5 - Rene Descartes;   Laboratoire Psychopathologie et Processus de Santé
Recruiting - verified May 2016

Patient Convenience Study- NIS RELATE

Condition:   Atrial Fibrillation
Interventions:   Drug: Pradaxa (dabigatran);   Drug: Vitamin K antagonist
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

Assessment of the Prevalence of Small Fiber Peripheral Neuropathy Among Non-diabetic Obese Patients

Condition:   Neuropathology
Intervention:   Device: Exams
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Recruiting - verified May 2016

Trhombus Aspiration in Hyperglycemic ST-elevation myocardiAl InfarcTIon

Condition:   Hyperglycemia
Intervention:   Device: percutaneous coronary intervention
Sponsor:   Second University of Naples
Completed - verified February 2017

Comparative Hybrid Effects of Combining BoNT-A With Robot-assisted or Mirror Therapy for U/E Spasticity Stroke Patients

Condition:   Stroke
Interventions:   Drug: Botulinum Toxin Type A;   Other: Robot-assisted therapy;   Other: Mirror therapy;   Other: Control intervention
Sponsor:   Chang Gung Memorial Hospital
Active, not recruiting - verified February 2016

Prospective Study Evaluating the Interest of Long-term Cardiac Recording in Cerebral Infarction

Condition:   Neuropathology
Intervention:   Device: Uses of SpiderFlash monitor
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Active, not recruiting - verified February 2017

Pectoral Nerves Blocks for Chronic Pain

Condition:   Breast Neoplasms
Interventions:   Drug: Ropivacaine;   Drug: Normal saline
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Recruiting - verified April 2016

Basilar Artery Occlusion Chinese Endovascular Trial

Conditions:   Basilar Artery Occlusion;   Ischemic Stroke;   Cerebrovascular Disorders
Interventions:   Procedure: Mechanical embolectomy;   Drug: Medical Treatment
Sponsors:   Xuanwu Hospital, Beijing;   Zhangzhou Municipal Hospital of Fujian Province;   The First People's Hospital of Changzhou;   Xinqiao Hospital of Chongqing;   Changhai Hospital;   Baotou Central Hospital;   The 101st Hospital of Chinese People's Liberation Army;   Linyi People's Hospital;   Zhongshan People's Hospital, Guangdong, China;   PLA 264 Hospital, Taiyuan, Shanxi;   Nanjing First People's Hospital;   Tianjin TEDA Hospital;   The First Affiliated Hospital with Nanjing Medical University;   Liaocheng Third People's Hospital;   Luoyang Central Hospital;   Subei People's Hospital of Jiangsu Province;   PLA 148 Hospital, Zibo, Shandong;   Hebei General Hospital;   Shengli Oilfield Hospital;   The 306 Hospital of People's Liberation Army;   Shenzhen Bao'an District People's Hospital;   First Hospital of Jilin University;   Henan Provincial Hospital;   Peking University Binhai Hospital;   Beijing Tiantan Hospital;   The Military General Hospital of Beijing, PLA;   The First Affiliated Hospital of Shanxi Medical University;   The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine;   Beijing Luhe Hospital;   Nantong University;   The Affiliated Hospital Of Guizhou Medical University;   Nanning Second People's Hospital;   Chongqing Three Gorges Central Hospital
Recruiting - verified June 2016

Comparative Effectiveness Research of Dual-task and Single-task Balance Training in People With Stroke

Condition:   Stroke
Interventions:   Device: single-task balance training;   Device: dual-task balance training
Sponsors:   Chang Gung University;   Mackay Memorial Hospital
Recruiting - verified February 2017

A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Recruiting - verified February 2017

Cholinergic Receptor Imaging in Dystonia

Conditions:   Cervical Dystonia;   Dystonia;   Movement Disorder;   Focal Dystonia
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified October 12, 2016

Safety and Efficacy Study of a Protease Activated Receptor-4 Antagonist Being Tested to Reduce the Chances of Having Additional Strokes or "Mini Strokes"

Condition:   Thrombosis
Interventions:   Drug: BMS-986141;   Drug: Aspirin;   Other: Placebo
Sponsor:   Bristol-Myers Squibb
Recruiting - verified July 2016

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Conditions:   Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified February 2017

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage

Condition:   Aortic Valve Disorder
Interventions:   Device: Lotus Heart valve system;   Device: WATCHMAN
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified February 2017

Watchman FLX Left Atrial Appendage Closure Device Post Approval Study

Condition:   Non-valvular Atrial Fibrillation
Intervention:   Device: Watchman FLX
Sponsor:   Boston Scientific Corporation
Not yet recruiting - verified February 2017

INVEST: Minimally Invasive Endoscopic Surgery vs. Medical Management in Supratentorial Intraparenchymal Hemorrhage

Condition:   Intracranial Hemorrhage
Interventions:   Device: Apollo MIES;   Other: Medical Management
Sponsor:   J. Mocco
Recruiting - verified February 2017

STAT-STatin and Aspirin in Trauma

Conditions:   Wounds and Injuries;   Venous Thromboembolism
Interventions:   Drug: Aspirin and Rosuvastatin;   Drug: Placebo (for Aspirin and Rosuvastatin)
Sponsor:   Denver Health and Hospital Authority
Recruiting - verified February 2017

Efficacy and Safety Study to Evaluate Vadadustat for the Correction of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Conditions:   Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified February 2017

Supernormal Oxygen Delivery for Elderly Surgical Patients

Condition:   Femoral Fractures
Interventions:   Procedure: SV maximization;   Procedure: supernormal DO2
Sponsor:   Guangzhou First Municipal People’s Hospital
Recruiting - verified February 2017

HBOT Global Functioning After Stroke

Condition:   Stroke
Interventions:   Other: Hyperbaric Oxygen Therapy (HBOT) and Exercise Program;   Other: Exercise Program;   Device: Hyperbaric Multiplace Chamber
Sponsor:   University Health Network, Toronto
Recruiting - verified February 2017

Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN

Conditions:   Heart Failure;   Iron Deficiency;   Left Ventricular Systolic Dysfunction
Intervention:   Drug: Iron (III) isomaltoside 1000
Sponsors:   University of Glasgow;   NHS Greater Glasgow and Clyde
Recruiting - verified February 2017

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified February 2017

Communicating Multiple Disease Risks

Condition:   Healthy
Interventions:   Behavioral: Cognitive interview;   Other: Survey
Sponsor:   Washington University School of Medicine
Suspended - verified February 2017

Predictors for Postoperative Delirium After Cardiac Surgery in Adults: a One-year, Single Center, Observational Cohort Study

Condition:   Postoperative Delirium
Intervention:   Other: no intervention
Sponsor:   University Hospital, Basel, Switzerland
Completed - verified February 2017

Patient Convenience Study

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Completed - verified February 2017

Home-based Transcranial Direct Current Stimulation in Fibromyalgia Patients

Condition:   Fibromyalgia
Interventions:   Other: Active-tDCS;   Other: Sham-tDCS
Sponsor:   Wolnei Caumo
Recruiting - verified February 2017

Feasibility Study of a Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Device: Aegis Sentinel Ligation System
Sponsors:   Aegis Medical Innovations;   Applied Health Research Centre
Not yet recruiting - verified February 2017

Hyperbaric Oxygen Post Established Stroke

Conditions:   Stroke;   Ischemic Stroke;   Established Stroke
Interventions:   Other: Hyperbaric Oxygen;   Other: Sham Hyperbaric Oxygen
Sponsor:   University of British Columbia
Recruiting - verified February 2017

Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis

Conditions:   Symptomatic Aortic Stenosis;   Eligible for Transcatheter Aortic Valve Replacement
Interventions:   Drug: Apixaban;   Drug: Standard of care
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Action Research Group;   Bristol-Meyers Squibb & Pfizer
Recruiting - verified February 2017

Special Drug Use Investigation of Xarelto for Venous Thromboembolism (VTE)

Condition:   Venous Thromboembolism
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified February 2017

ERic Acute StrokE Recanalization (ERASER)

Condition:   Ischemic Stroke
Intervention:   Device: ERIC® and SOFIA™
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Recruiting - verified February 2017

The Study to Reevaluate the Safety and Efficacy of Human Urinary Kallikrein

Condition:   Cerebral Infarction
Intervention:   Drug: kallikrein
Sponsor:   Techpool Bio-Pharma Co., Ltd.
Enrolling by invitation - verified February 2017

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified February 2017

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

Conditions:   Secondary Prevention;   Stroke;   Ischemic Heart Disease;   Coronary Heart Disease
Interventions:   Drug: Acetylsalicylic Acid (Asprin, BAYE4465);   Drug: Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
Sponsor:   Bayer
Recruiting - verified February 2017

HT-3951 vs. Placebo in Stroke Rehabilitation

Condition:   Ischemic Stroke
Interventions:   Drug: HT-3951;   Drug: Placebo
Sponsor:   Dart NeuroScience, LLC
Recruiting - verified February 2017

Stroke and Traumatic Acute Brain Injury Line Indicator System for Emergent Recognition (STABILISER-I)

Conditions:   Ischemic Stroke;   Hemorrhagic Stroke;   Traumatic Brain Injury
Intervention:   Device: Lateral Flow Device
Sponsors:   Justin Fraser;   University of Kentucky
Completed - verified February 2017

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified February 2017

Short-Term Dual Antiplatelet and Maintenance CloPidogrel Therapy After Drug-Eluting Stent Implantation

Condition:   Coronary Artery Disease
Interventions:   Drug: Clopidogrel;   Drug: Aspirin plus clopidogrel
Sponsors:   CHEOL WHAN LEE, M.D., Ph.D;   CardioVascular Research Foundation, Korea;   Medtronic;   Chong Kun Dang Pharmaceutical Corp.
Terminated - verified February 2017

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Active, not recruiting - verified February 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

An Observational Cross-sectional Study Evaluating the Sociodemographic and Clinical Characteristics of Patients Diagnosed With NVAF With a Risk of Stroke or Systemic Embolism, Who Are on Treatment to Adequately Control Their Coagulation and Treated in Primary Care Centres

Conditions:   Stroke;   Prevention and Control;   Atrial Fibrillation
Intervention:   Drug: Direct Oral Anticoagulant (DOAC)
Sponsor:   Bayer
Completed - verified February 2017

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion
Recruiting - verified February 2017

Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS

Conditions:   Brain Injury;   Central Nervous System Degenerative Disorder;   Central Nervous System Infectious Disorder;   Central Nervous System Vascular Malformation;   Hemorrhagic Cerebrovascular Accident;   Ischemic Cerebrovascular Accident;   Primary Brain Neoplasm;   Brain Cancer;   Brain Tumors
Interventions:   Drug: Ferumoxytol;   Other: Tissue Analysis;   Procedure: Magnetic Resonance Imaging
Sponsor:   Michael Iv
Active, not recruiting - verified February 2017

Hybrid Versus Catheter Ablation in Persistent AF

Condition:   Atrial Fibrillation
Interventions:   Procedure: Hybrid Ablation;   Procedure: Catheter Ablation
Sponsor:   Maastricht University Medical Center
Recruiting - verified February 2017

An Extension Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine Extended-Release Tablets for the Treatment of Chronic Post-Ischemic Stroke Walking Deficits in Subjects Who Participated in the DALF-PS-1016 Study

Condition:   Post-ischemic Stroke
Interventions:   Drug: dalfampridine-ER 7.5 mg;   Drug: dalfampridine-ER 10 mg
Sponsor:   Acorda Therapeutics
Terminated - verified February 2017

Oral Guanabenz for Multiple Sclerosis

Conditions:   Multiple Sclerosis, Relapsing-Remitting;   Multiple Sclerosis
Intervention:   Drug: Guanabenz
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified December 29, 2016

Ablation Verses Anti-arrhythmic Therapy for Reducing All Hospital Episodes From Recurrent Atrial Fibrillation

Conditions:   Heart Failure;   Recurrent Atrial Fibrillation
Interventions:   Procedure: AVATAR-AF ablation;   Drug: Anti-Arrhythmic therapy;   Procedure: Conventional AF ablation
Sponsor:   Imperial College London
Recruiting - verified August 2016

Hong Kong Outpatient AF Screening Using Single-lead ECG Device

Condition:   Atrial Fibrillation
Interventions:   Other: Patient education;   Other: Routine care
Sponsors:   Chinese University of Hong Kong;   University of Sydney
Recruiting - verified February 2017

Cord Blood Infusion for Ischemic Stroke

Condition:   Stroke
Intervention:   Biological: allogeneic umbilical cord blood
Sponsor:   Joanne Kurtzberg, MD
Active, not recruiting - verified February 2017

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified February 2017

Telerehabilitation in the Home Versus Therapy In-Clinic for Patients With Stroke

Condition:   Stroke
Interventions:   Device: Telerehabilitation Therapy;   Behavioral: In-Clinic Therapy
Sponsor:   University of California, Irvine
Recruiting - verified February 2017

DLBS1033 for the Treatment of Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: Placebo;   Drug: DLBS1033
Sponsor:   Dexa Medica Group
Terminated - verified February 2017

Novel Treatment of Intermittent Claudication in Patients With Peripheral Arterial Disease Using Danshen Gegen (D&G) Capsule

Conditions:   Peripheral Arterial Disease;   Intermittent Claudication
Interventions:   Drug: Danshen Gegen Capsule;   Drug: Placebo
Sponsor:   Chinese University of Hong Kong
Recruiting - verified February 2017

Quality of Life and Rehabilitation Pathway in Northern Norway and Denmark.

Conditions:   Stroke;   Quality of Life
Intervention:  
Sponsor:   University Hospital of North Norway
Active, not recruiting - verified January 2017

Validation of Rivaroxaban Assay for US Registration

Condition:   Patients Receiving Rivaroxaban Treatment
Intervention:   Device: STA- Rivaroxaban Calibrator&Control
Sponsor:   Diagnostica Stago
Completed - verified February 2017

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified February 2017

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified February 2017

VNS During Rehabilitation for Improved Upper Limb Motor Function After Stroke

Conditions:   Stroke;   Upper Limb Deficits
Intervention:   Device: Vagus Nerve Stimulation (VNS)
Sponsor:   MicroTransponder Inc.
Active, not recruiting - verified February 2017

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified February 2017

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

French Database of Left Atrial Appendage Closure

Condition:   Atrial Fibrillation and Other Dysrhythmias | Patient
Intervention:   Other: Percutaneous Left Atrial Appendage Closure in routine care
Sponsors:   Henri Mondor University Hospital;   French association for research in cardiology (ARCARD)
Active, not recruiting - verified February 2016

Potentiation of the Effects of Prismatic Adaptation by Transcranial Direct Current Stimulation (tDCS) : Evaluation of Functional Interest in Negligence Rehabilitation

Condition:   Neurologic Neglect Syndrome
Interventions:   Device: transcranial direct current stimulation (tDCS);   Device: Control: placebo stimulation
Sponsor:   Hospices Civils de Lyon
Recruiting - verified February 2017

Brain Stimulation in Movement Disorders

Conditions:   Huntington's Disease;   Tourette Syndrome
Intervention:   Other: Transcranial direct current stimulation
Sponsors:   Birmingham and Solihull Mental Health NHS Foundation Trust;   University of Birmingham
Active, not recruiting - verified February 2017

Refinement and Clinical Evaluation of the H-Man for Arm Rehabilitation After Stroke

Condition:   Stroke
Interventions:   Device: H-Man;   Other: Additional Conventional Therapy
Sponsors:   Tan Tock Seng Hospital;   National Medical Research Council (NMRC), Singapore
Recruiting - verified February 2017

Active Surveillance Research Program for the Assessment of the Safety and the Effectiveness of Linagliptin

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified February 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified February 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Placebo
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified February 2017

Vascular Dysfunction in Paediatric IBD

Conditions:   Inflammatory Bowel Disease;   Crohn Disease;   Ulcerative Colitis
Intervention:  
Sponsors:   Great Ormond Street Hospital for Children NHS Foundation Trust;   National Institute for Health Research, United Kingdom
Completed - verified February 2017

SITS (Safe Implementation of Treatments in Stroke) Open Artery by Thrombectomy in Acute Occlusive Stroke Study

Condition:   Ischemic Stroke
Interventions:   Device: Stent retriever endovascular device for thrombectomy;   Drug: Intravenous thrombolysis by alteplase (Actilyse)
Sponsors:   Karolinska Institutet;   Swedish Heart Lung Foundation;   Medtronic - MITG;   Stryker Nordic;   Phenox GmbH
Recruiting - verified February 2017

Comparison of Thrombectomy and Standard Care for Ischemic Stroke in Patients Ineligibility for Tissue Plasminogen Activator Treatment

Condition:   Ischemic Stroke
Interventions:   Device: Thrombectomy;   Other: Best medical care
Sponsors:   University Hospital Heidelberg;   University Hospital, Aachen;   Klinikum Augsburg;   Vivantes Krankenhaus Berlin Neukölln;   Ruhr University of Bochum;   Klinikum Dortmund Wirbelsäulenchirurgie;   University of Erlangen-Nürnberg Medical School;   Alfried Krupp Krankenhaus Essen;   University Hospital, Essen;   University Hospital Freiburg;   University Medical Center Goettingen;   Universitätsklinikum Hamburg-Eppendorf;   Universitätsklinik für Neuroradiologie Innsbruck;   Universitätsklinikum Köln;   The Wagner-Jauregg Provincial Neuropsychiatric Clinic;   Klinikum der Universitaet Muenchen;   Klinikum rechst der Isar Technische Universitaet Muenchen;   KLINIKUM VEST Recklinghausen;   Wuerzburg University Hospital;   Asklepios Kliniken Hamburg GmbH
Terminated - verified February 2017

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Completed - verified June 2016

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

Conditions:   Cardiomyopathy;   Coronary Artery Disease;   Congestive Heart Failure;   Myocardial Infarction
Interventions:   Device: Implantable Cardioverter Defibrillator;   Other: Optimal Medical Therapy
Sponsor:   VA Office of Research and Development
Recruiting - verified February 2017

A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke

Condition:   Stroke
Interventions:   Drug: Alteplase;   Drug: Alteplase Placebo;   Drug: Aspirin;   Drug: Aspirin Placebo
Sponsor:   Genentech, Inc.
Active, not recruiting - verified February 2017

Interactive Intention-Driven Upper-Limb Training Robotic System

Condition:   Stroke
Interventions:   Device: Hand Robotic Training;   Device: Hand and Arm Robotic Training;   Other: Conventional therapy
Sponsor:   The Hong Kong Polytechnic University
Completed - verified February 2017

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Completed - verified February 2017

VASSTII: An Exploratory Clinical Study on a VASST IITreadmill System for Post Stroke Gait Rehabilitation.

Conditions:   Stroke;   Hemiplegic Gait
Intervention:   Device: VASST
Sponsors:   Tan Tock Seng Hospital;   Ngee Ann Polytechnic
Recruiting - verified February 2017

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Ticagrelor 60 mg;   Drug: Ticagrelor placebo
Sponsor:   AstraZeneca
Active, not recruiting - verified February 2017

Use of Dabigatran Etexilate to Prevent Stroke and Thromboembolism

Conditions:   Atrial Fibrillation;   Atrial Flutter
Intervention:   Drug: dabigatran etexilate mesylate
Sponsors:   Vanderbilt University Medical Center;   Boehringer Ingelheim
Active, not recruiting - verified February 2017

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Terminated - verified February 2017

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Terminated - verified February 2017

Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care

Conditions:   Diabetes Mellitus;   Hypertension;   Coronary Artery Disease;   Atrial Fibrillation;   Stroke
Interventions:   Other: PHCVRS Intervention;   Other: Personal Health Record
Sponsor:   Barry L. Carter
Active, not recruiting - verified February 2017

A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: insulin degludec;   Drug: insulin glargine
Sponsor:   Novo Nordisk A/S
Completed - verified February 2017

The Efficacy of Citalopram Treatment in Acute Stroke

Condition:   Stroke, Ischemic
Interventions:   Drug: Citalopram;   Drug: Placebo
Sponsors:   University of Aarhus;   Danish Council for Independent Research;   The Danish Regions Medicine Foundation
Completed - verified December 2016

A Study of Post-Stroke Pain and Fatigue: Clinical Evaluation and Treatment Effect

Condition:   Stroke
Interventions:   Device: Combined Therapy of FES and BAT;   Device: Conventional Rehabilitation
Sponsors:   Chang Gung University;   Mackay Memorial Hospital;   Chang Gung Memorial Hospital
Recruiting - verified February 2017

Cortical Recording and Stimulating Array Brain-Machine Interface

Conditions:   Tetraplegia;   Spinal Cord Injury;   Brainstem Stroke
Intervention:   Device: Implantation of CRS Arrays
Sponsors:   University of Pittsburgh;   Defense Advanced Research Projects Agency;   United States Department of Defense;   Johns Hopkins University
Recruiting - verified February 2017

Cerebrospinal Fluid Collection and Repository Storage

Condition:   Neurological Diseases
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified October 11, 2016

Focal Cortical Atrophy After Myocardial Internal Capsule

Condition:   Ischemic Stroke
Intervention:   Other: Additional MRI
Sponsor:   University Hospital, Toulouse
Completed - verified February 2017

Skeletal Muscle Biomarkers in People With Fragile Sarcolemmal Muscular Dystrophy

Condition:   Genetic Disorder
Intervention:  
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Neurological Disorders and Stroke (NINDS);   National Institutes of Health Clinical Center (CC);   University of Massachusetts, Worcester
Recruiting - verified December 15, 2016

Anticoagulant Utilization Pattern

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute;   Janssen Research & Development, LLC
Recruiting - verified February 2017

Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)

Condition:   Acute Heart Failure
Interventions:   Drug: Liraglutide;   Drug: Placebo
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2017

Impact of Platelet Rich Plasma Over Alternative Therapies in Patients With Lateral Epicondylitis

Condition:   Tennis Elbow
Interventions:   Biological: Group A Platelet Rich Plasma Injection (PRP);   Procedure: Group B Whole Blood Injection;   Procedure: Group C Dry Needle tendon fenestration;   Other: Group D No injection
Sponsor:   Jon Jacobson
Active, not recruiting - verified February 2017

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Omarigliptin;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified February 2017

Reparative Therapy in Acute Ischemic Stroke With Allogenic Mesenchymal Stem Cells From Adipose Tissue, Safety Assessment, a Randomised, Double Blind Placebo Controlled Single Center Pilot Clinical Trial

Condition:   Ischemic Stroke
Interventions:   Drug: Allogenic mesenchymal stem cells from adipose tissue;   Drug: Placebo
Sponsor:   Instituto de Investigación Hospital Universitario La Paz
Recruiting - verified February 2017

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

Study of HC-58 in Upper Limb Hemiplegic Patients After Stroke

Condition:   Severe Upper Limb Hemiplegia
Interventions:   Drug: HC-58;   Drug: Placebo
Sponsor:   Asahi Kasei Pharma Corporation
Completed - verified February 2015

Impact of Vitamin D Supplementation on Cardiac Structure and Function

Condition:   Cardiovascular Disease
Interventions:   Dietary Supplement: Vitamin D3 + fish oil/fish oil placebo;   Dietary Supplement: Vitamin D3 placebo + fish oil/fish oil placebo
Sponsors:   Massachusetts General Hospital;   Brigham and Women's Hospital
Active, not recruiting - verified February 2017

AAV2-GDNF for Advanced Parkinson s Disease

Condition:   Parkinson's Disease
Intervention:   Genetic: Convection enhanced delivery/AAV2-GDNF
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 13, 2017

Xarelto [SPAF] Post-marketing Surveillance in Japan

Condition:   Brain Ischemia
Intervention:   Drug: Rivaroxaban(Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Active, not recruiting - verified February 2017

Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome

Conditions:   Klinefelter Syndrome;   XXY Syndrome
Interventions:   Drug: Testosterone gel 1%;   Drug: Placebo gel
Sponsors:   University of Colorado, Denver;   Colorado Clinical & Translational Sciences Institute;   Children's Hospital Colorado;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2017

Imaging the Effect of Centrotemporal Spikes and Seizures on Language in Children

Condition:   Benign Childhood Epilepsy With Centro-Temporal Spikes
Intervention:   Drug: Levetiracetam
Sponsors:   Children's Hospital Medical Center, Cincinnati;   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified February 2017

Functional Interest of Non Invasive Brain Stimulation During Physiotherapy at a Subacute Phase Post Stroke (Anodal Protocol): ReSTIM

Condition:   Stroke
Interventions:   Device: anodal tDCS (device) Eldith DC-Stimulator;   Device: Sham tDCS
Sponsor:   Hospices Civils de Lyon
Recruiting - verified February 2017

Post-Marketing Surveillance of Prazaxa® on the Long-term Use in Patients With Nonvalvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Prazaxa
Sponsor:   Boehringer Ingelheim
Completed - verified February 2017

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Completed - verified February 2017

Microelectrode Brain-Machine Interface for Individuals With Tetraplegia

Conditions:   Tetraplegia;   Spinal Cord Injury
Intervention:   Device: Implantation of NeuroPort Arrays in the motor cortex
Sponsors:   University of Pittsburgh;   United States Department of Defense;   Johns Hopkins University
Recruiting - verified February 2017

French National Cohort of Children With Port Wine Stain

Conditions:   Port Wine Stain;   Klippel Trenaunay Syndrome;   Parkes Weber Syndrome
Intervention:   Genetic: search for polymorphisms of RASA1 gene
Sponsor:   University Hospital, Tours
Active, not recruiting - verified February 2017

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Conditions:   Atherosclerosis;   Hypercholesterolemia
Interventions:   Drug: Statin Drugs;   Other: HMG-CoA Reductase Inhibitors
Sponsor:   National Institutes of Health Clinical Center (CC)
Completed - verified March 21, 2016

CANVAS - CANagliflozin cardioVascular Assessment Study

Conditions:   Diabetes Mellitus, Type 2;   Cardiovascular Diseases;   Risk Factors
Interventions:   Drug: Canagliflozin (JNJ-28431754);   Drug: Placebo
Sponsors:   Janssen Research & Development, LLC;   The George Institute for Global Health, Australia
Active, not recruiting - verified February 2017

The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Darapladib 160 mg;   Drug: Placebo;   Other: Standard Therapy
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Completed - verified February 2017

Ecosystem Focused Therapy for Treating Older Depressed Stroke Survivors

Conditions:   Ischemic Stroke;   Depression
Interventions:   Behavioral: Ecosystem Focused Therapy (EFT);   Behavioral: Education in stroke and depression
Sponsors:   Weill Medical College of Cornell University;   National Institute of Mental Health (NIMH)
Completed - verified February 2017

The Role of Factor XIII Activation Peptide and D-dimer Values for the Diagnosis of Cerebral Venous Thrombosis (CVT)

Condition:   Cerebral Venous Thrombosis
Intervention:   Other: ELISA Test
Sponsors:   University Hospital Inselspital, Berne;   Schweizerische Herzstiftung
Recruiting - verified February 2017

Non-invasive Brain Stimulation and Occupational Therapy To Enhance Stroke Recovery

Conditions:   Stroke;   Cerebrovascular Accident;   CVA;   Acute Stroke;   Acute Cerebrovascular Accident;   Apoplexy
Interventions:   Device: Transcranial Direct Current Stimulation;   Device: Transcranial Direct Current Stimulation
Sponsor:   Beth Israel Deaconess Medical Center
Active, not recruiting - verified February 2017

Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease

Condition:   Krabbe Disease
Intervention:  
Sponsors:   Maria Escolar;   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified February 2017

Autonomic Function in Obstructive Sleep Apnea

Condition:   Obstructive Sleep Apnea
Intervention:   Other: continuous positive airway pressure (CPAP)
Sponsors:   Vanderbilt University;   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified February 2017

Prospective Randomized Study of Brain Protection During Aortic Arch Replacement

Condition:   Aneurysm of Aortic Arch
Interventions:   Procedure: Retrograde brain perfusion;   Procedure: Antegrade brain perfusion
Sponsor:   The Cleveland Clinic
Completed - verified February 2017

Multimodal Resonance Imaging for Outcome Prediction on Coma Patients

Condition:   Coma
Intervention:   Procedure: Multimodal MRI
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed - verified December 2008

Effect of Diet on Vascular Disease in Pre-Menopausal Women

Conditions:   Cardiovascular Diseases;   Vascular Disease;   Inflammation;   Insulin;   Triglycerides
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified February 14, 2017

Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo

Condition:   Epilepsies, Partial
Interventions:   Drug: Lyrica (pregabalin);   Drug: placebo
Sponsor:   Pfizer
Recruiting - verified February 2017

Nutrition Intervention Trials in Linxian Follow-up Study

Conditions:   Esophageal Cancer;   Gastric Cancer
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified February 13, 2017

Balloon Prophylaxis of Aneurysmal Vasospasm

Conditions:   Aneurysm;   Vasospasm
Interventions:   Procedure: transluminal ballooning;   Other: currently existing therapies for the treatment of vasospasm
Sponsors:   University of California, Davis;   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified March 2014

A Randomized Trial of Changing Medication Adherence In Hypertensive African-American Patients

Condition:   Hypertension
Intervention:   Behavioral: Intervention Group
Sponsor:   Weill Medical College of Cornell University
Completed - verified February 2017

Exploring Folk Health Practices in Latinos With Chronic Medical Conditions

Conditions:   Diabetes;   Hypertension;   Asthma;   Heart Disease;   Stroke;   Arthritis
Intervention:  
Sponsor:   Weill Medical College of Cornell University
Completed - verified February 2017

Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)

Condition:   Coronary Artery Disease
Intervention:   Drug: pexelizumab in conjunction with CABG
Sponsors:   Alexion Pharmaceuticals;   Procter and Gamble
Active, not recruiting - verified February 2017

Pelvic Pain in Women With Endometriosis

Conditions:   Endometriosis;   Pelvic Pain;   Healthy;   Tubal Ligation
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified September 6, 2016

Human Movement Database

Conditions:   Healthy;   Movement Disorder
Intervention:  
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified January 27, 2017