Stroke

Clinical Trial Finder

Many patients who have experienced a stroke are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Electrical Impedance Tomography of Stroke and Brain Injury

Conditions:   Stroke;   Craniocerebral Injuries
Intervention:   Device: Electrical Impedance Tomography
Sponsors:   University College, London;   University College London Hospitals
Recruiting - verified October 2016

Exercise and Brain Stimulation for Post-stroke Depression

Condition:   Stroke
Interventions:   Behavioral: Aerobic exercise;   Other: Repetitive transcranial magnetic stimulation
Sponsor:   Medical University of South Carolina
Recruiting - verified February 2017

Evaluating the Indego Exoskeleton for Persons With Hemiplegia Due to CVA

Conditions:   Cerebrovascular Accident (CVA);   Stroke;   Hemiplegia
Intervention:   Device: Indego Exoskeleton
Sponsors:   Parker Hannifin Corporation;   Shepherd Center, Atlanta GA;   Cedars-Sinai Medical Center;   Sheltering Arms Physical Rehabilitation Hospitals;   Rehabilitation Institute of Chicago;   Kessler Foundation;   St. Charles Hospital;   TIRR Memorial Hermann;   Rusk Rehabilitation
Not yet recruiting - verified February 2017

Functional Viability Duck Duck Punch

Conditions:   Rehabilitation;   Recovery of Function;   Stroke
Interventions:   Device: Duck Duck Punch Play;   Behavioral: Commercially Available Game Play
Sponsors:   Medical University of South Carolina;   National Institutes of Health (NIH);   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2017

The Effect of a Walking Assist Robot on Gait Function and Brain Activity in Stroke Patients and Elderly Adults

Conditions:   Stroke;   Healthy
Interventions:   Procedure: Gait, sit-to-stand movement and stair climbing;   Procedure: Sit-to-stand movement and treadmill gait;   Device: gait enhancing mechatronic system (GEMS);   Device: treadmill
Sponsors:   Samsung Medical Center;   Samsung Electronics
Not yet recruiting - verified February 2017

Dysphagia After Different Swallowing Therapies

Conditions:   Dysphagia;   Videofluoroscopy;   Stroke
Interventions:   Other: general swallowing therapy;   Other: NMES therapy
Sponsor:   Chang Gung Memorial Hospital
Completed - verified February 2017

Functional Connectivity as a Biomarker of rTMS

Condition:   Traumatic Brain Injury
Intervention:   Device: rTMS
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 1, 2017

Electrical Impedance Tomography of Epilepsy

Condition:   Epilepsy
Intervention:   Device: Electrical Impedance Tomography
Sponsors:   University College, London;   University College London Hospitals
Not yet recruiting - verified February 2017

Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies (GREFEX II)

Conditions:   Alzheimer Disease;   Parkinson Disease;   Frontal Dementia;   Huntington Disease;   Traumatic Brain Injury;   Stroke
Intervention:   Behavioral: social cognition
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified February 2017

SpecTRA; An Observational Study of the Verification of Protein Biomarkers in Transient Ischemic Attack.

Condition:   TIA
Intervention:   Other: Non-Interventional Study
Sponsors:   Andrew Penn;   Genome Canada;   Genome British Columbia;   Genome Alberta;   Heart and Stroke Foundation of Canada;   Stroke Services BC;   Bruker Daltonics;   LifeLabs
Completed - verified February 2017

Ferric Citrate in ESRD Pilot Project

Conditions:   End Stage Renal Disease;   Chronic Kidney Diseases
Intervention:   Drug: Ferric Citrate
Sponsors:   Sreedhar Mandayam;   Keryx Biopharmaceuticals
Recruiting - verified February 2017

Study of Arterial Recanalization of the Central Retinal Artery Occlusions

Condition:   Central Retinal Artery Occlusion
Intervention:  
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified February 2017

Relationship Between Pelvic Tilt and Sit to Stand Task in Stroke Patients

Condition:   Stroke
Intervention:   Other: Pelvic tilt assessment
Sponsor:   Cairo University
Completed - verified February 2017

Colchicine and Spironolactone in Patients With STEMI / SYNERGY Stent Registry

Condition:   ST Elevation Myocardial Infarction
Interventions:   Drug: Colchicine;   Drug: Spironolactone;   Device: SYNERGY Bioabsorbable Polymer Drug-Eluting Stent;   Drug: Colchicine-Placebo;   Drug: Spironolactone-Placebo
Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research (CIHR);   Boston Scientific Corporation
Not yet recruiting - verified February 2017

Vascular Cell Activation, Cell-Derived Microparticles and In Vitro Fertilisation, and In Vitro Fertilisation

Conditions:   Infertility;   Hyperstimulation Syndrome, Ovaian;   Thrombosis
Intervention:  
Sponsors:   Poissy-Saint Germain Hospital;   Agence de La Biomédecine
Completed - verified February 2017

Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training

Conditions:   Complete Spinal Cord Injury;   Incomplete Spinal Cord Injury;   Acquired Brain Injury;   Multiple Sclerosis
Interventions:   Device: ReWalk;   Device: EKSO;   Device: REX
Sponsor:   The University of Texas Health Science Center, Houston
Recruiting - verified February 2017

Treatment Development of Triheptanoin (G1D)

Conditions:   Epilepsy;   GLUT1DS1;   Glut1 Deficiency Syndrome 1, Autosomal Recessive;   Glucose Metabolism Disorders;   Glucose Transport Defect;   Glucose Transporter Type 1 Deficiency Syndrome;   Glucose Transporter Protein Type 1 Deficiency Syndrome
Intervention:   Drug: Triheptanoin
Sponsors:   University of Texas Southwestern Medical Center;   National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting - verified February 2017

Platelet Acetyl Coenzyme A Carboxylase Phosphorylation in Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome;   Coronary Thrombosis
Intervention:   Diagnostic Test: Platelet Acetyl Coenzyme A Carboxylase analysis in CAD
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Completed - verified February 2017

Assessment of the St Jude Medical Portico Resheathable Aortic Valve System-Alternative Access

Condition:   Aortic Valve Stenosis
Intervention:   Device: TAVI
Sponsor:   St. Jude Medical
Not yet recruiting - verified February 2017

Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies

Condition:   Pyruvate Dehydrogenase Complex Deficiency Disease
Intervention:   Other: No intervention
Sponsors:   University Hospitals Cleveland Medical Center;   Rare Diseases Clinical Research Network;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2017

The British Heart Foundation SENIOR-RITA Trial

Condition:   NSTEMI - Non-ST Segment Elevation MI
Interventions:   Procedure: Coronary Angiography;   Procedure: Coronary revascularisation;   Other: Optimal Medical Therapy
Sponsors:   Newcastle-upon-Tyne Hospitals NHS Trust;   British Heart Foundation;   Newcastle University
Recruiting - verified February 2017

Safety and Efficacy of the Symetis ACURATE Neo/TF Compared to the Edwards SAPIEN 3 Bioprosthesis.

Condition:   Aortic Valve Stenosis
Interventions:   Device: Symetis ACURATE neo/TF transfemoral TAVI system;   Device: Edwards Sapien 3 Transcatheter Heart Valve
Sponsors:   University Hospital Inselspital, Berne;   Kerckhoff Heart Center
Recruiting - verified February 2017

Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke

Conditions:   Stroke;   Stroke, Acute;   Brain Injury, Acute
Interventions:   Biological: Umbilical Cord Blood;   Other: Placebo
Sponsors:   Joanne Kurtzberg, MD;   The Marcus Foundation;   Emory University;   M.D. Anderson Cancer Center
Recruiting - verified February 2017

Acupuncture Treatment on Motor Dysfunction in Stroke Patients

Conditions:   Stroke;   Motor Disorders
Interventions:   Other: Acupuncture Treatment;   Other: Rehabilitation Treatment
Sponsors:   Shanghai University of Traditional Chinese Medicine;   Fudan University
Recruiting - verified November 2016

TCM Clinical Practice Rehabilitation of Post-stroke Spasticity

Condition:   Stroke
Interventions:   Other: Modern rehabilitation treatment;   Other: Modern rehabilitation &TCM;   Other: modern rehabilitation &Baimai Ruangao;   Other: modern rehabilitation &Tibetan medicine
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified February 2017

Reproducibility Study of Transcranial Doppler

Condition:   Stroke
Intervention:   Diagnostic Test: Transcranial Doppler Ultrasound
Sponsor:   University of Edinburgh
Not yet recruiting - verified February 2017

Automated Physician Notifications to Improve Guideline-Based Anticoagulation in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Other: Baseline alert
Sponsors:   Massachusetts General Hospital;   Boehringer Ingelheim
Active, not recruiting - verified February 2017

Safety and Efficacy of Alteplase When Administered in Chinese Patients With Acute Ischemic Hemispheric Stroke Where Thrombolysis is Initiated Between 3 and 4.5 Hours After Stroke Onset

Condition:   Stroke
Intervention:   Drug: alteplase
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

Peripheral Nerve Stimulation for Shoulder Pain: Dose Response

Conditions:   Stroke;   Shoulder Pain
Intervention:   Device: Peripheral Nerve Stimulation
Sponsors:   MetroHealth Medical Center;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Case Western Reserve University
Recruiting - verified February 2017

Whole Brain Vessel Wall Imaging in Stroke Patients (WISP): An International Multi-Center Registry

Condition:   Stroke
Intervention:   Device: MRI
Sponsor:   Cedars-Sinai Medical Center
Enrolling by invitation - verified February 2017

Radial Shock Waves for Functional Disability in Stroke

Condition:   Ischemic Stroke
Interventions:   Device: Active Radial Shockwave;   Device: Sham Radial Shockwave
Sponsor:   Marta Imamura
Recruiting - verified February 2017

Heart of Virginia Healthcare

Condition:   Cardiovascular Diseases
Intervention:   Other: Quality Improvement Support
Sponsors:   Virginia Commonwealth University;   Virginia Center for Health Innovation;   Center for Health Policy Development;   George Mason University;   Health Quality Innovators
Enrolling by invitation - verified February 2017

Impact of Neutrophil Activation in Acute Ischemic Stroke Patients Treated With Endovascular Therapy

Condition:   Acute Stroke
Intervention:  
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified February 2017

Impact of Neutrophil Extracellular Traps on Tissue Plasminogen Activator Induced Thrombolysis in Acute Ischemic Stroke Patients

Condition:   Acute Stroke
Intervention:  
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified February 2017

Long Term Assessment of Post Thrombotic Syndrome : OPTIMEV Study ( SPOT )

Conditions:   Post Thrombotic Syndrome;   Venous Thromboembolism;   Cardiovascular Diseases
Interventions:   Other: Villalta phone score > or = to 5;   Other: Villalta phone score < 5
Sponsors:   Association des Médecins Vasculaires Hospitaliers;   Daiichi Sankyo Inc.;   Ministry of Health, France;   LEO Pharma;   Sanofi;   University Hospital, Grenoble
Not yet recruiting - verified February 2017

Assessment of Patients' Early Neurological Clinical Recovery, 3 Months After Endovascular Treatment of an Acute Ischemic Stroke

Condition:   Stroke, Acute
Intervention:  
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Recruiting - verified February 2017

AMPLATZER™ Amulet™ LAA Occluder Trial

Condition:   Stroke
Interventions:   Device: Amulet Left Atrial Appendage Occluder;   Device: WATCHMAN Left Atrial Appendage Closure
Sponsor:   St. Jude Medical
Recruiting - verified February 2017

Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist

Condition:   Intracerebral Hemorrhage
Interventions:   Drug: Tranexamic acid;   Drug: Saline 0.9%
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation
Recruiting - verified February 2017

Efficacy and Safety Study to Evaluate Vadadustat for the Correction of Anemia in Subjects With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD)

Conditions:   Anemia;   Dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: Darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified February 2017

Acupuncture Lowering Blood Pressure for Secondary Prevention of Stroke

Condition:   Cerebral Infarction
Intervention:   Device: acupuncture
Sponsors:   First Teaching Hospital of Tianjin University of Traditional Chinese Medicine;   State Administration of Traditional Chinese Medicine of the People's Republic of China
Recruiting - verified February 2017

Abnormal Ventilatory Response to Carbon Dioxide: a Potential Biomarker for Seizure Induced Respiratory Depression & Modification by SSRI

Conditions:   Epilepsy;   SUDEP
Interventions:   Drug: Fluoxetine;   Drug: Placebo
Sponsor:   University of Iowa
Recruiting - verified February 2017

Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques

Condition:   Multiple Sclerosis
Interventions:   Drug: Methylprednisolone;   Drug: Methylprednisolone
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Enrolling by invitation - verified October 12, 2016

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

Trhombus Aspiration in Hyperglycemic ST-elevation myocardiAl InfarcTIon

Condition:   Hyperglycemia
Intervention:   Device: percutaneous coronary intervention
Sponsor:   Second University of Naples
Completed - verified February 2017

Comparative Hybrid Effects of Combining BoNT-A With Robot-assisted or Mirror Therapy for U/E Spasticity Stroke Patients

Condition:   Stroke
Interventions:   Drug: Botulinum Toxin Type A;   Other: Robot-assisted therapy;   Other: Mirror therapy;   Other: Control intervention
Sponsor:   Chang Gung Memorial Hospital
Active, not recruiting - verified February 2016

Pectoral Nerves Blocks for Chronic Pain

Condition:   Breast Neoplasms
Interventions:   Drug: Ropivacaine;   Drug: Normal saline
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Recruiting - verified April 2016

Basilar Artery Occlusion Chinese Endovascular Trial

Conditions:   Basilar Artery Occlusion;   Ischemic Stroke;   Cerebrovascular Disorders
Interventions:   Procedure: Mechanical embolectomy;   Drug: Medical Treatment
Sponsors:   Xuanwu Hospital, Beijing;   Zhangzhou Municipal Hospital of Fujian Province;   The First People's Hospital of Changzhou;   Xinqiao Hospital of Chongqing;   Changhai Hospital;   Baotou Central Hospital;   The 101st Hospital of Chinese People's Liberation Army;   Linyi People's Hospital;   Zhongshan People's Hospital, Guangdong, China;   PLA 264 Hospital, Taiyuan, Shanxi;   Nanjing First People's Hospital;   Tianjin TEDA Hospital;   The First Affiliated Hospital with Nanjing Medical University;   Liaocheng Third People's Hospital;   Luoyang Central Hospital;   Subei People's Hospital of Jiangsu Province;   PLA 148 Hospital, Zibo, Shandong;   Hebei General Hospital;   Shengli Oilfield Hospital;   The 306 Hospital of People's Liberation Army;   Shenzhen Bao'an District People's Hospital;   First Hospital of Jilin University;   Henan Provincial Hospital;   Peking University Binhai Hospital;   Beijing Tiantan Hospital;   The Military General Hospital of Beijing, PLA;   The First Affiliated Hospital of Shanxi Medical University;   The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine;   Beijing Luhe Hospital;   Nantong University;   The Affiliated Hospital Of Guizhou Medical University;   Nanning Second People's Hospital;   Chongqing Three Gorges Central Hospital
Recruiting - verified June 2016

Comparative Effectiveness Research of Dual-task and Single-task Balance Training in People With Stroke

Condition:   Stroke
Interventions:   Device: single-task balance training;   Device: dual-task balance training
Sponsors:   Chang Gung University;   Mackay Memorial Hospital
Recruiting - verified February 2017

A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Recruiting - verified February 2017

Cholinergic Receptor Imaging in Dystonia

Conditions:   Cervical Dystonia;   Dystonia;   Movement Disorder;   Focal Dystonia
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified October 12, 2016

Safety and Efficacy Study of a Protease Activated Receptor-4 Antagonist Being Tested to Reduce the Chances of Having Additional Strokes or "Mini Strokes"

Condition:   Thrombosis
Interventions:   Drug: BMS-986141;   Drug: Aspirin;   Other: Placebo
Sponsor:   Bristol-Myers Squibb
Recruiting - verified July 2016

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Conditions:   Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified February 2017

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage

Condition:   Aortic Valve Disorder
Interventions:   Device: Lotus Heart valve system;   Device: WATCHMAN
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified February 2017

Watchman FLX Left Atrial Appendage Closure Device Post Approval Study

Condition:   Non-valvular Atrial Fibrillation
Intervention:   Device: Watchman FLX
Sponsor:   Boston Scientific Corporation
Not yet recruiting - verified February 2017

INVEST: Minimally Invasive Endoscopic Surgery vs. Medical Management in Supratentorial Intraparenchymal Hemorrhage

Condition:   Intracranial Hemorrhage
Interventions:   Device: Apollo MIES;   Other: Medical Management
Sponsor:   J. Mocco
Recruiting - verified February 2017

STAT-STatin and Aspirin in Trauma

Conditions:   Wounds and Injuries;   Venous Thromboembolism
Interventions:   Drug: Aspirin and Rosuvastatin;   Drug: Placebo (for Aspirin and Rosuvastatin)
Sponsor:   Denver Health and Hospital Authority
Recruiting - verified February 2017

Efficacy and Safety Study to Evaluate Vadadustat for the Correction of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Conditions:   Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions:   Drug: vadadustat;   Drug: darbepoetin alfa
Sponsor:   Akebia Therapeutics
Recruiting - verified February 2017

Supernormal Oxygen Delivery for Elderly Surgical Patients

Condition:   Femoral Fractures
Interventions:   Procedure: SV maximization;   Procedure: supernormal DO2
Sponsor:   Guangzhou First Municipal People’s Hospital
Recruiting - verified February 2017

Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN

Conditions:   Heart Failure;   Iron Deficiency;   Left Ventricular Systolic Dysfunction
Intervention:   Drug: Iron (III) isomaltoside 1000
Sponsors:   University of Glasgow;   NHS Greater Glasgow and Clyde
Recruiting - verified February 2017

Characteristics of Balance Control to Unexpected Loss of Balance During Standing and Walking in Post-stroke Individuals

Condition:   Stroke
Interventions:   Device: BalanceTutor;   Device: posturograph
Sponsors:   Nachum Soroker, MD;   Ben-Gurion University of the Negev
Recruiting - verified February 2017

Plasma ExtrAcellular RNAs and Biomarkers of Heart FaiLure During Decongestion: PEARL-HF Study

Condition:   Congestive Heart Failure
Intervention:   Other: Monitoring on heart failure therapy
Sponsors:   Massachusetts General Hospital;   Beth Israel Deaconess Medical Center
Recruiting - verified February 2017

Communicating Multiple Disease Risks

Condition:   Healthy
Interventions:   Behavioral: Cognitive interview;   Other: Survey
Sponsor:   Washington University School of Medicine
Suspended - verified February 2017

Predictors for Postoperative Delirium After Cardiac Surgery in Adults: a One-year, Single Center, Observational Cohort Study

Condition:   Postoperative Delirium
Intervention:   Other: no intervention
Sponsor:   University Hospital, Basel, Switzerland
Completed - verified February 2017

The Correlation Between Hair Cortisol Level of Acute Stroke or Its Long Term Disability.

Condition:   Cerebrovascular Stroke
Intervention:  
Sponsor:   Bnai Zion Medical Center
Recruiting - verified February 2017

Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults

Condition:   Sialorrhea
Intervention:   Drug: MYOBLOC
Sponsor:   US WorldMeds LLC
Active, not recruiting - verified February 2017

Feasibility Study of a Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Device: Aegis Sentinel Ligation System
Sponsors:   Aegis Medical Innovations;   Applied Health Research Centre
Not yet recruiting - verified February 2017

ERic Acute StrokE Recanalization (ERASER)

Condition:   Ischemic Stroke
Intervention:   Device: ERIC® and SOFIA™
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Recruiting - verified February 2017

The Study to Reevaluate the Safety and Efficacy of Human Urinary Kallikrein

Condition:   Cerebral Infarction
Intervention:   Drug: kallikrein
Sponsor:   Techpool Bio-Pharma Co., Ltd.
Enrolling by invitation - verified February 2017

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified February 2017

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

Conditions:   Secondary Prevention;   Stroke;   Ischemic Heart Disease;   Coronary Heart Disease
Interventions:   Drug: Acetylsalicylic Acid (Asprin, BAYE4465);   Drug: Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
Sponsor:   Bayer
Recruiting - verified February 2017

Interest of Direct Aspiration First Pass Technique (ADAPT) for Thrombectomy Revascularisation of Large Vessel Occlusion in Acute Ischaemic Stroke

Condition:   Ischemic Cerebrovascular Accident
Interventions:   Procedure: direct aspiration procedure;   Procedure: stent retriever procedure
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Active, not recruiting - verified February 2017

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified February 2017

HT-3951 vs. Placebo in Stroke Rehabilitation

Condition:   Ischemic Stroke
Interventions:   Drug: HT-3951;   Drug: Placebo
Sponsor:   Dart NeuroScience, LLC
Recruiting - verified February 2017

Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS

Condition:   Acute Coronary Syndrome
Interventions:   Drug: dalcetrapib;   Drug: Placebo
Sponsors:   DalCor Pharmaceuticals;   The Montreal Health Innovations Coordinating Center (MHICC);   Medpace, Inc.;   Roche Molecular Systems, Inc
Recruiting - verified February 2017

Fluid Responsiveness Prediction Using Extra Systoles

Condition:   Fluid Responsiveness
Intervention:  
Sponsors:   University of Aarhus;   Philips Healthcare
Completed - verified May 2016

Characterizing Hemodynamic Compensation in Patients With Intracranial Stenosis

Conditions:   Stroke;   Intracranial Stenosis
Intervention:  
Sponsor:   Vanderbilt University
Active, not recruiting - verified February 2017

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Active, not recruiting - verified February 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

An Observational Cross-sectional Study Evaluating the Sociodemographic and Clinical Characteristics of Patients Diagnosed With NVAF With a Risk of Stroke or Systemic Embolism, Who Are on Treatment to Adequately Control Their Coagulation and Treated in Primary Care Centres

Conditions:   Stroke;   Prevention and Control;   Atrial Fibrillation
Intervention:   Drug: Direct Oral Anticoagulant (DOAC)
Sponsor:   Bayer
Completed - verified February 2017

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion
Recruiting - verified February 2017

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Completed - verified February 2017

Hybrid Versus Catheter Ablation in Persistent AF

Condition:   Atrial Fibrillation
Interventions:   Procedure: Hybrid Ablation;   Procedure: Catheter Ablation
Sponsor:   Maastricht University Medical Center
Recruiting - verified February 2017

An Extension Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine Extended-Release Tablets for the Treatment of Chronic Post-Ischemic Stroke Walking Deficits in Subjects Who Participated in the DALF-PS-1016 Study

Condition:   Post-ischemic Stroke
Interventions:   Drug: dalfampridine-ER 7.5 mg;   Drug: dalfampridine-ER 10 mg
Sponsor:   Acorda Therapeutics
Terminated - verified February 2017

Oral Guanabenz for Multiple Sclerosis

Conditions:   Multiple Sclerosis, Relapsing-Remitting;   Multiple Sclerosis
Intervention:   Drug: Guanabenz
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified December 29, 2016

Ablation Verses Anti-arrhythmic Therapy for Reducing All Hospital Episodes From Recurrent Atrial Fibrillation

Conditions:   Heart Failure;   Recurrent Atrial Fibrillation
Interventions:   Procedure: AVATAR-AF ablation;   Drug: Anti-Arrhythmic therapy;   Procedure: Conventional AF ablation
Sponsor:   Imperial College London
Recruiting - verified August 2016

Cord Blood Infusion for Ischemic Stroke

Condition:   Stroke
Intervention:   Biological: allogeneic umbilical cord blood
Sponsor:   Joanne Kurtzberg, MD
Active, not recruiting - verified February 2017

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2016

Lakeshore Examination of Activity and Disability Exercise Response Study

Conditions:   Multiple Sclerosis;   Stroke
Interventions:   Behavioral: Movement to Music;   Behavioral: Adapted Yoga
Sponsors:   University of Alabama at Birmingham;   Lakeshore Foundation
Recruiting - verified February 2017

Telerehabilitation in the Home Versus Therapy In-Clinic for Patients With Stroke

Condition:   Stroke
Interventions:   Device: Telerehabilitation Therapy;   Behavioral: In-Clinic Therapy
Sponsor:   University of California, Irvine
Recruiting - verified February 2017

DLBS1033 for the Treatment of Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: Placebo;   Drug: DLBS1033
Sponsor:   Dexa Medica Group
Terminated - verified February 2017

Evaluating the Feasibility and Usability of Exergames in Stroke Patients With Visuo-spatial Neglect

Condition:   Hemispatial Neglect
Intervention:   Other: Neglect Exergames
Sponsor:   University of Zurich
Completed - verified February 2017

Home-Based Screening for Early Detection of Atrial Fibrillation in Primary Care Patients Aged 75 Years and Older

Conditions:   Atrial Fibrillation;   Hypertension
Intervention:   Device: Screening: Intervention - Atrial fibrillation screening (ZIO XT ECG monitor, Watch-BP)
Sponsors:   Population Health Research Institute;   Canadian Stroke Prevention Intervention Network;   Canadian Institutes of Health Research (CIHR);   Heart and Stroke Foundation of Canada;   Canadian Stroke Network;   Boehringer Ingelheim;   iRhythm Technologies, Inc.;   Microlife
Recruiting - verified February 2017

Canadian Community Utilization of Stroke Prevention Study - Emergency Department

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Other: Retrospective review of OAC prescription;   Other: Prescription of OAC in ED;   Other: Community AF clinic
Sponsor:   Population Health Research Institute
Active, not recruiting - verified February 2017

Validation of Rivaroxaban Assay for US Registration

Condition:   Patients Receiving Rivaroxaban Treatment
Intervention:   Device: STA- Rivaroxaban Calibrator&Control
Sponsor:   Diagnostica Stago
Completed - verified February 2017

Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS)

Condition:   Stroke
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin (Acetylsalicylic acid, BAY1019036);   Other: Rivaroxaban-Placebo;   Other: Aspirin-Placebo
Sponsors:   Bayer;   Janssen, LP;   Hamilton Health Sciences Cooperation, Population Health Research Institute
Recruiting - verified February 2017

Virtual Reality Exercise for Stroke Rehabilitation in Inpatients Who Are Unable to Stand

Condition:   Stroke
Interventions:   Other: virtual reality training;   Other: control
Sponsors:   Bruyere Research Institute;   Ottawa Hospital Research Institute;   University of Ottawa;   Heart and Stroke Foundation of Canada
Recruiting - verified February 2017

Study of Ticagrelor Versus Aspirin Treatment in Patients With Myocardial Injury Post Major Non-cardiac Surgery

Condition:   Myocardial Injury
Interventions:   Drug: ticagrelor;   Drug: aspirin
Sponsors:   The Cleveland Clinic;   AstraZeneca
Terminated - verified February 2017

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified February 2017

Program for the Identification of "Actionable" Atrial Fibrillation in the Family Practice Setting

Condition:   Atrial Fibrillation
Interventions:   Other: 30 Second Pulse Check;   Device: Watch BP Home A;   Device: HeartCheck Hand-held ECG device
Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research (CIHR)
Completed - verified February 2017

VNS During Rehabilitation for Improved Upper Limb Motor Function After Stroke

Conditions:   Stroke;   Upper Limb Deficits
Intervention:   Device: Vagus Nerve Stimulation (VNS)
Sponsor:   MicroTransponder Inc.
Active, not recruiting - verified February 2017

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

Combined Antagonistic Muscle Magnetic Stimulation and Selective Periferal Neurotomy to Improve Results on Spasticity

Condition:   STROKE
Interventions:   Procedure: - Postoperative Antagonistic Peripheral Magnetic Stimulation;   Device: Selected Peripheral Magnetic Stimulation;   Other: Kinesics
Sponsor:   Juan Carlos M. Andreani
Not yet recruiting - verified February 2017

Potentiation of the Effects of Prismatic Adaptation by Transcranial Direct Current Stimulation (tDCS) : Evaluation of Functional Interest in Negligence Rehabilitation

Condition:   Neurologic Neglect Syndrome
Interventions:   Device: transcranial direct current stimulation (tDCS);   Device: Control: placebo stimulation
Sponsor:   Hospices Civils de Lyon
Recruiting - verified February 2017

Brain Stimulation in Movement Disorders

Conditions:   Huntington's Disease;   Tourette Syndrome
Intervention:   Other: Transcranial direct current stimulation
Sponsors:   Birmingham and Solihull Mental Health NHS Foundation Trust;   University of Birmingham
Active, not recruiting - verified February 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified February 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Placebo
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified February 2017

DLBS1033 for Acute Ischemic Stroke Patients

Conditions:   Acute Ischemic Stroke;   Partial Anterior Circulation Infarct;   Lacunar Anterior Circulation Infarct
Interventions:   Drug: DLBS1033;   Drug: Placebo
Sponsor:   Dexa Medica Group
Recruiting - verified February 2017

Comparison of Thrombectomy and Standard Care for Ischemic Stroke in Patients Ineligibility for Tissue Plasminogen Activator Treatment

Condition:   Ischemic Stroke
Interventions:   Device: Thrombectomy;   Other: Best medical care
Sponsors:   University Hospital Heidelberg;   University Hospital, Aachen;   Klinikum Augsburg;   Vivantes Krankenhaus Berlin Neukölln;   Ruhr University of Bochum;   Klinikum Dortmund Wirbelsäulenchirurgie;   University of Erlangen-Nürnberg Medical School;   Alfried Krupp Krankenhaus Essen;   University Hospital, Essen;   University Hospital Freiburg;   University Medical Center Goettingen;   Universitätsklinikum Hamburg-Eppendorf;   Universitätsklinik für Neuroradiologie Innsbruck;   Universitätsklinikum Köln;   The Wagner-Jauregg Provincial Neuropsychiatric Clinic;   Klinikum der Universitaet Muenchen;   Klinikum rechst der Isar Technische Universitaet Muenchen;   KLINIKUM VEST Recklinghausen;   Wuerzburg University Hospital;   Asklepios Kliniken Hamburg GmbH
Terminated - verified February 2017

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Completed - verified June 2016

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

Conditions:   Cardiomyopathy;   Coronary Artery Disease;   Congestive Heart Failure;   Myocardial Infarction
Interventions:   Device: Implantable Cardioverter Defibrillator;   Other: Optimal Medical Therapy
Sponsor:   VA Office of Research and Development
Recruiting - verified February 2017

A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke

Condition:   Stroke
Interventions:   Drug: Alteplase;   Drug: Alteplase Placebo;   Drug: Aspirin;   Drug: Aspirin Placebo
Sponsor:   Genentech, Inc.
Terminated - verified February 2017

Combinational Rehabilitative Therapy and Functional Brain Imaging for Patients Recovering From Motor Stroke

Condition:   Ischaemic Stroke
Interventions:   Drug: Levodopa;   Other: Virtual Reality based therapy
Sponsors:   Singapore General Hospital;   Singapore University of Technology and Design
Completed - verified February 2017

The PARTNER TRIAL - Post Approval Study Part II

Conditions:   Severe;   Symptomatic;   Calcific Aortic Stenosis
Intervention:   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Sponsors:   Edwards Lifesciences;   American College of Cardiology;   Society of Thoracic Surgeons (STS)
Active, not recruiting - verified February 2017

Atrial Fibrillation Detected by Continuous ECG Monitoring

Conditions:   Atrial Fibrillation;   Stroke;   Hypertension;   Diabetes
Intervention:   Device: LOOP recorder (Medtronic LINQ device)
Sponsors:   Rigshospitalet, Denmark;   Bispebjerg Hospital;   Zealand University Hospital;   Odense University Hospital;   University of Southern Denmark;   Aalborg University
Active, not recruiting - verified February 2017

Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects

Condition:   Sialorrhea
Interventions:   Drug: MYOBLOC;   Other: PLACEBO
Sponsor:   US WorldMeds LLC
Completed - verified February 2017

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Terminated - verified February 2017

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Terminated - verified February 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

A Study of Post-Stroke Pain and Fatigue: Clinical Evaluation and Treatment Effect

Condition:   Stroke
Interventions:   Device: Combined Therapy of FES and BAT;   Device: Conventional Rehabilitation
Sponsors:   Chang Gung University;   Mackay Memorial Hospital;   Chang Gung Memorial Hospital
Recruiting - verified February 2017

Cortical Recording and Stimulating Array Brain-Machine Interface

Conditions:   Tetraplegia;   Spinal Cord Injury;   Brainstem Stroke
Intervention:   Device: Implantation of CRS Arrays
Sponsors:   University of Pittsburgh;   Defense Advanced Research Projects Agency;   United States Department of Defense;   Johns Hopkins University
Recruiting - verified February 2017

Cerebrospinal Fluid Collection and Repository Storage

Condition:   Neurological Diseases
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified October 11, 2016

Exercise Education for Adults With Seizure Disorders

Conditions:   Seizures;   Epilepsy
Interventions:   Other: Patient Education;   Other: exercise: increase physical activity/goal setting
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified January 25, 2017

GLP-1 and Hypoglycemia

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Glucagon-Like Peptide- 1 (GLP-1) infusion;   Other: Placebo Comparator: Saline Infusion
Sponsor:   University of Maryland
Recruiting - verified February 2017

Study Of Diabetic Nephropathy With Atrasentan

Condition:   Diabetic Nephropathy
Interventions:   Drug: Atrasentan;   Drug: Placebo
Sponsor:   AbbVie
Recruiting - verified February 2017

Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)

Condition:   Acute Heart Failure
Interventions:   Drug: Liraglutide;   Drug: Placebo
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2017

On-treatment PLAtelet Reactivity-guided Therapy Modification FOR ST-segment Elevation Myocardial Infarction

Condition:   Acute ST-elevation Myocardial Infarction
Intervention:   Drug: Antiplatelet Regimen Modification (aspirin or ticagrelor)
Sponsor:   Clinical Centre of Serbia
Recruiting - verified February 2017

Reparative Therapy in Acute Ischemic Stroke With Allogenic Mesenchymal Stem Cells From Adipose Tissue, Safety Assessment, a Randomised, Double Blind Placebo Controlled Single Center Pilot Clinical Trial

Condition:   Ischemic Stroke
Interventions:   Drug: Allogenic mesenchymal stem cells from adipose tissue;   Drug: Placebo
Sponsor:   Instituto de Investigación Hospital Universitario La Paz
Recruiting - verified February 2017

Study of HC-58 in Upper Limb Hemiplegic Patients After Stroke

Condition:   Severe Upper Limb Hemiplegia
Interventions:   Drug: HC-58;   Drug: Placebo
Sponsor:   Asahi Kasei Pharma Corporation
Completed - verified February 2015

Impact of Vitamin D Supplementation on Cardiac Structure and Function

Condition:   Cardiovascular Disease
Interventions:   Dietary Supplement: Vitamin D3 + fish oil/fish oil placebo;   Dietary Supplement: Vitamin D3 placebo + fish oil/fish oil placebo
Sponsors:   Massachusetts General Hospital;   Brigham and Women's Hospital
Active, not recruiting - verified February 2017

AAV2-GDNF for Advanced Parkinson s Disease

Condition:   Parkinson's Disease
Intervention:   Genetic: Convection enhanced delivery/AAV2-GDNF
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 13, 2017

Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome

Conditions:   Klinefelter Syndrome;   XXY Syndrome
Interventions:   Drug: Testosterone gel 1%;   Drug: Placebo gel
Sponsors:   University of Colorado, Denver;   Colorado Clinical & Translational Sciences Institute;   Children's Hospital Colorado;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified February 2017

Functional Interest of Non Invasive Brain Stimulation During Physiotherapy at a Subacute Phase Post Stroke (Anodal Protocol): ReSTIM

Condition:   Stroke
Interventions:   Device: anodal tDCS (device) Eldith DC-Stimulator;   Device: Sham tDCS
Sponsor:   Hospices Civils de Lyon
Recruiting - verified February 2017

Post-Marketing Surveillance of Prazaxa® on the Long-term Use in Patients With Nonvalvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Prazaxa
Sponsor:   Boehringer Ingelheim
Completed - verified February 2017

REGISTRY EVALUATION OF VITAL INFORMATION FOR VADs IN AMBULATORY LIFE

Condition:   Congestive Heart Failure
Intervention:   Other: No Intervention
Sponsors:   University of Michigan;   National Heart, Lung, and Blood Institute (NHLBI);   Brigham and Women's Hospital
Active, not recruiting - verified February 2017

Microelectrode Brain-Machine Interface for Individuals With Tetraplegia

Conditions:   Tetraplegia;   Spinal Cord Injury
Intervention:   Device: Implantation of NeuroPort Arrays in the motor cortex
Sponsors:   University of Pittsburgh;   United States Department of Defense;   Johns Hopkins University
Recruiting - verified February 2017

Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis

Condition:   Sinus Thrombosis, Intracranial
Interventions:   Drug: Endovascular thrombolysis;   Drug: Heparin
Sponsors:   Jan Stam, MD, PhD;   Dutch Heart Foundation
Terminated - verified November 2016

Bilateral Bispectral Index (BIS) Study

Conditions:   Cerebral Vasospasm;   Delayed Cerebral Ischemia;   Subarachnoid Hemorrhage
Intervention:  
Sponsor:   Icahn School of Medicine at Mount Sinai
Completed - verified February 2017

The Role of Factor XIII Activation Peptide and D-dimer Values for the Diagnosis of Cerebral Venous Thrombosis (CVT)

Condition:   Cerebral Venous Thrombosis
Intervention:   Other: ELISA Test
Sponsors:   University Hospital Inselspital, Berne;   Schweizerische Herzstiftung
Recruiting - verified February 2017

Metabolic Causes of Thrombosis in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes
Interventions:   Procedure: euinsulinemic euglycemic glucose clamp;   Procedure: euinsulinemic hyperglycemic glucose clamp;   Procedure: Hyperinsulinemic euglycemic glucose clamp;   Procedure: Hyperinsulinemic hyperglycemic glucose clamp
Sponsors:   University of Maryland;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2017

Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease

Condition:   Krabbe Disease
Intervention:  
Sponsors:   Maria Escolar;   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified February 2017

Biomarkers of Risk of Parkinson Disease

Conditions:   Parkinson Disease;   Autonomic Nervous System Diseases;   Pure Autonomic Failure
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified November 29, 2016

RIVastigmine In Vascular cognitivE Impairment

Condition:   Cognitive Impairment
Interventions:   Drug: Exelon (rivastigmine);   Drug: Placebo
Sponsors:   Singapore General Hospital;   Novartis;   National Neuroscience Institute
Completed - verified February 2017

Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)

Condition:   Sturge - Weber Syndrome (SWS)
Intervention:   Other: blood sample tear drop sample
Sponsors:   University of California, Irvine;   Mainz University
Completed - verified February 2017

Prospective Randomized Study of Brain Protection During Aortic Arch Replacement

Condition:   Aneurysm of Aortic Arch
Interventions:   Procedure: Retrograde brain perfusion;   Procedure: Antegrade brain perfusion
Sponsor:   The Cleveland Clinic
Completed - verified February 2017

Effect of Diet on Vascular Disease in Pre-Menopausal Women

Conditions:   Cardiovascular Diseases;   Vascular Disease;   Inflammation;   Insulin;   Triglycerides
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified February 14, 2017

Heart Outcomes Prevention Evaluation-3

Conditions:   Cardiovascular Disease;   Stroke
Interventions:   Drug: Candesartan/HCT;   Drug: Rosuvastatin
Sponsor:   Population Health Research Institute
Completed - verified February 2017

Nutrition Intervention Trials in Linxian Follow-up Study

Conditions:   Esophageal Cancer;   Gastric Cancer
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified February 13, 2017

Balloon Prophylaxis of Aneurysmal Vasospasm

Conditions:   Aneurysm;   Vasospasm
Interventions:   Procedure: transluminal ballooning;   Other: currently existing therapies for the treatment of vasospasm
Sponsors:   University of California, Davis;   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified March 2014

In Vitro Studies on Pharmacological Regulation and Genetic Risk Factors of Peripheral Human Nociceptors

Condition:   Pain
Intervention:  
Sponsors:   The University of Texas Health Science Center at San Antonio;   National Institutes of Health (NIH);   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified February 2017

Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)

Condition:   Coronary Artery Disease
Intervention:   Drug: pexelizumab in conjunction with CABG
Sponsors:   Alexion Pharmaceuticals;   Procter and Gamble
Active, not recruiting - verified February 2017

Pelvic Pain in Women With Endometriosis

Conditions:   Endometriosis;   Pelvic Pain;   Healthy;   Tubal Ligation
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified September 6, 2016

Human Movement Database

Conditions:   Healthy;   Movement Disorder
Intervention:  
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified January 27, 2017