Prediabetes

Clinical Trial Finder

Many patients with prediabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Coronary Artery Disease Progression in Patients With Prediabetes

Conditions:   Coronary Artery Disease;   Atherosclerosis;   Prediabetic State
Interventions:   Drug: Metformin;   Behavioral: Lifestyle recommendations
Sponsor:   Pauls Stradins Clinical University Hospital
Recruiting - verified April 2016

ForgIng New Paths to Prevent DIabeTes (FINDIT)

Condition:   Prediabetes
Interventions:   Behavioral: Blood Test Group Intervention;   Behavioral: Brochure Group Intervention
Sponsor:   VA Office of Research and Development
Recruiting - verified April 2016

Effect of Pravastatin in the Subjects With Prediabetes or Early Diabetes

Conditions:   Diabetes Mellitus;   Prediabetic State
Interventions:   Drug: Pravastatin;   Drug: Placebo (for Pravastatin)
Sponsors:   Samsung Medical Center;   Daiichi Sankyo Korea Co., Ltd.
Recruiting - verified April 2016

Smart Technology for Weight Loss and Metabolic Health

Conditions:   Obesity;   Overweight;   Prediabetes;   Weight Loss;   Lifestyle
Interventions:   Device: Wearable technology, smartscale;   Behavioral: Smartphone applications;   Behavioral: Standard Weight Management Visits
Sponsors:   Temple University;   The Obesity Treatment Foundation
Not yet recruiting - verified April 2016

G-CREDIT (Gangnam-Cohort for Risk Evaluation of Diabetes and Impaired Glucose Tolerance)

Conditions:   Type 2 Diabetes;   Impaired Glucose Intolerance
Intervention:  
Sponsor:   Yonsei University
Not yet recruiting - verified April 2016

Replacing Refined Carbohydrates With Healthy Fats on Cardio-metabolic Markers

Conditions:   Pre-diabetes;   Metabolic Syndrome
Interventions:   Dietary Supplement: Active;   Dietary Supplement: Control
Sponsor:   Institute for Food Safety and Health, United States
Recruiting - verified April 2016

The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes

Conditions:   Prediabetic State;   Obesity
Interventions:   Drug: Dapagliflozin;   Drug: Metformin;   Behavioral: Exercise
Sponsors:   Steno Diabetes Center;   The Novo Nordic Foundation;   Rigshospitalet, Denmark;   AstraZeneca;   Bayer
Recruiting - verified April 2016

Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2)

Condition:   Pre-diabetes
Interventions:   Drug: epicatechin;   Drug: Placebo
Sponsors:   Veterans Medical Research Foundation;   San Diego Veterans Healthcare System;   National Center for Complementary and Integrative Health (NCCIH);   University of California, San Diego;   National Institutes of Health (NIH)
Completed - verified April 2016

Effects of Polyphenols Found in Pomegranate Juice on Postprandial Blood Glucose in Vivo

Condition:   Hyperglycaemia
Interventions:   Other: Control without pomegranate juice;   Other: Test with pomegranate juice
Sponsor:   University of Leeds
Completed - verified April 2016

Development of Pre-pregnancy Intervention to Reduce the Risk of Diabetes and Prediabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Intervention:   Dietary Supplement: No treatment given
Sponsor:   Novo Nordisk A/S
Recruiting - verified December 2015

Effect of LIK066 on Body Weight in Patients With Elevated Body Mass Index

Condition:   Elevated Body Mass Index
Interventions:   Drug: LIK066;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Completed - verified April 2016

Effects of Polyphenols Found in Pomegranate and Olives Food Supplements on Postprandial Blood Glucose in Vivo.

Condition:   Hyperglycaemia
Interventions:   Other: Control (109 g white bread);   Dietary Supplement: Dose 1;   Dietary Supplement: Dose 2
Sponsor:   University of Leeds
Completed - verified April 2016

Prohealth@Home: A Feasibility Study Investigating the Use of a Lifestyle App in People at Risk of Type 2 Diabetes

Condition:   Pre-diabetes
Intervention:   Behavioral: Lifestyle counselling
Sponsor:   University of Plymouth
Completed - verified April 2016

The MoMMii Study. Diabetes Prevention Intervention on Families With Past Gestational Diabetes

Condition:   Gestational Diabetes Mellitus With Baby Delivered
Intervention:   Behavioral: Nutrition/physical activity intervention
Sponsors:   McGill University Health Center;   The Lawson Foundation
Active, not recruiting - verified April 2016

Effects of DPP4 Inhibitor on Cisplatin Induced Acute Kidney Injury

Conditions:   Cancer;   Cisplatin Adverse Reaction
Interventions:   Drug: Gemigliptin;   Drug: Placebo;   Drug: Cisplatin
Sponsors:   Seoul National University Bundang Hospital;   LG Life Sciences
Recruiting - verified April 2016

Effects of Liraglutide on Hippocampal Structure and Function in Aging Adults With Prediabetes

Conditions:   Insulin Resistance;   Dementia
Interventions:   Drug: Liraglutide;   Drug: Placebo
Sponsors:   Stanford University;   American Diabetes Association
Recruiting - verified April 2016

Effects of Mifepristone on Biomarkers of Metabolic Function and Neuropsychological Performance Among Middle-Aged and Older Individuals

Condition:   Depression
Intervention:   Drug: 28 days treatment with Mifepristone.
Sponsor:   Stanford University
Recruiting - verified April 2016

Latinos Combating Diabetes

Conditions:   Pre Diabetes;   Obesity;   Metabolic Syndrome
Interventions:   Behavioral: Lifestyle Weight Loss;   Behavioral: Counseling
Sponsors:   Wake Forest School of Medicine;   National Institute on Minority Health and Health Disparities (NIMHD)
Recruiting - verified April 2016

High Protein Breakfast on Appetite, Postprandial Glycemia and Weight Loss in T2D

Conditions:   Obese;   Pre-diabetes
Interventions:   Other: Arm 1 Whey Breakfast;   Other: Arm 2 No Whey Breakfast;   Other: Arm 3 Low Protein Breakfast
Sponsors:   Hospital de Clinicas Caracas;   Tel Aviv University
Active, not recruiting - verified September 2015

Prevention of Cystic Fibrosis Diabetes

Conditions:   Cystic Fibrosis;   Prediabetes
Intervention:   Drug: Sitagliptin
Sponsor:   Emory University
Recruiting - verified April 2016

Healthy Living Partnership to Prevent Diabetes

Conditions:   Prediabetes;   Obesity
Interventions:   Behavioral: Group-Based Lifestyle Intervention (Phases 1 and 2);   Other: Individual Education Program (All Phases);   Behavioral: Self-Directed Maintenance (Phase 3);   Behavioral: Extended Group Maintenance (Phase 3)
Sponsors:   Wake Forest Baptist Health;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified April 2016