Prediabetes

Clinical Trial Finder

Many patients with prediabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Muscle Accrual and Function in Cystic Fibrosis-Impact of Glucose Intolerance

Condition:   Cystic Fibrosis
Intervention:  
Sponsors:   Children's Hospital of Philadelphia;   National Institutes of Health (NIH);   University of Pennsylvania;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified May 2016

Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism

Conditions:   Overweight;   Obesity;   Dysglycemia;   Prediabetes;   Metabolic Syndrome;   Type 2 Diabetes
Intervention:   Other: fructose, allulose, tagatose, or sorbose
Sponsors:   University of Toronto;   Canadian Diabetes Association;   The Physicians' Services Incorporated Foundation;   Banting and Best Diabetes Centre;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2016

Assessment of the Prevalence of Small Fiber Peripheral Neuropathy Among Non-diabetic Obese Patients

Condition:   Neuropathology
Intervention:   Device: Exams
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Recruiting - verified May 2016

Body Composition and White Adipose Tissue Inflammation

Conditions:   Breast Cancer;   Prostate Cancer;   Body Composition;   White Adipose Tissue Inflammation
Interventions:   Device: DEXA Scan;   Behavioral: Godin Leisure Time Exercise Questionnaire (GLTEQ)
Sponsors:   Memorial Sloan Kettering Cancer Center;   Weill Medical College of Cornell University
Recruiting - verified May 2016

Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk

Conditions:   Obesity;   Dyslipidemia;   Prediabetes;   Dysglycemia;   Gout;   Hypertension;   Non-Alcoholic Fatty Liver Disease;   Cardiovascular Disease
Interventions:   Other: High Fructose Corn Syrup;   Other: Sucrose
Sponsors:   University of Toronto;   Canadian Institutes of Health Research (CIHR);   The Physicians' Services Incorporated Foundation;   Banting and Best Diabetes Centre (BBDC)
Active, not recruiting - verified May 2016

Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors

Conditions:   Dyslipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Gout;   Hypertension;   Non-alcoholic Fatty Liver Disease;   Cardiovascular Disease
Intervention:   Other: Fructose-containing Sugars
Sponsors:   University of Toronto;   Canadian Diabetes Association (CDA);   The Physicians' Services Incorporated Foundation;   Banting and Best Diabetes Centre (BBDC)
Active, not recruiting - verified May 2016

Meta-analyses of Liquid Versus Solid Calories and Body Weight

Conditions:   Diabetes Mellitus;   Chronic Disease;   Cardiovascular Diseases;   Prediabetic State;   Overweight;   Obesity;   Metabolic Syndrome
Intervention:   Other: Liquid calories from sugars
Sponsors:   John Sievenpiper;   The Physicians' Services Incorporated Foundation;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2016

Replacing Refined Carbohydrates With Healthy Fats on Cardio-metabolic Markers

Conditions:   Pre-diabetes;   Metabolic Syndrome
Interventions:   Dietary Supplement: Active;   Dietary Supplement: Control
Sponsor:   Institute for Food Safety and Health, United States
Recruiting - verified May 2016

Reducing Dexamethasone Around Docetaxel Infusion

Conditions:   Breast Cancer;   Prostate Cancer
Interventions:   Drug: Dexamethasone;   Drug: Prednisone
Sponsor:   Leiden University Medical Center
Recruiting - verified May 2016

Getting in Balance: A Workplace Diabetes Prevention Intervention Trial

Conditions:   Diabetes Mellitus, Type 2;   Overweight;   Obesity
Interventions:   Behavioral: In-Person Diabetes Prevention Program;   Behavioral: Online Diabetes Prevention Program
Sponsor:   Kaiser Permanente
Recruiting - verified May 2016

Bridging Income Generation With Group Integrated Care

Conditions:   Cardiovascular Disease;   Diabetes
Interventions:   Other: Usual Clinical Care;   Other: Group Medical Visits;   Other: Microfinance Groups
Sponsors:   Icahn School of Medicine at Mount Sinai;   Moi University College of Health Sciences;   Brown University;   Duke University;   Purdue University;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified May 2016

The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients

Condition:   Cystic Fibrosis
Interventions:   Drug: novolog insulin;   Drug: levemir insulin;   Drug: placebo
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Children's Hospitals and Clinics of Minnesota
Recruiting - verified May 2016

Community-based Adolescent Diabetes Prevention Program

Condition:   Pre-Diabetes
Intervention:   Behavioral: TEEN HEED
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting - verified May 2016

Fit and Trim for Diabetes Prevention

Conditions:   Pre-diabetes;   Overweight;   Obese
Intervention:   Behavioral: Filipinos Fit and Trim Weight Loss Program
Sponsors:   University of California, San Francisco;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Active, not recruiting - verified May 2016

PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes

Conditions:   Diabetes;   Obesity
Interventions:   Behavioral: Pre-study dietary and exercise instruction.;   Procedure: Screening examination and oral glucose tolerance test;   Procedure: Euglycemic clamp;   Procedure: VO2max.;   Behavioral: Acute exercise bout;   Procedure: Percutaneous needle muscle biopsies
Sponsors:   Mayo Clinic;   Arizona State University
Terminated - verified May 2016

Dose-dependent Effect of Grape Seed Extract on Glucose Control in People With Impaired Glucose Tolerance

Condition:   Impaired Glucose Tolerance
Interventions:   Dietary Supplement: 0 mg placebo;   Dietary Supplement: 300 mg GSE;   Dietary Supplement: 600 mg GSE;   Dietary Supplement: 900 mg GSE
Sponsor:   Institute for Food Safety and Health, United States
Active, not recruiting - verified May 2016

The Tailgate Study: A Pilot Study Measuring the Impact of Acute Alcohol Intake on Intrahepatic Lipid

Condition:   Obesity
Intervention:  
Sponsor:   University of Missouri-Columbia
Recruiting - verified May 2016

Effects of Antidiabetic Medications on the Postprandial State in Prediabetes

Conditions:   Prediabetes;   Obesity
Interventions:   Drug: Exenatide;   Drug: Saxagliptin;   Drug: Exenatide ER;   Other: Placebo
Sponsors:   The University of Texas Health Science Center, Houston;   The Center for Clinical and Translational Sciences (CCTS) Clinical Research Unit at The University of Texas Health Science Center at Houston
Recruiting - verified May 2016

Role of Growth Hormone Antagonism in Modulating Insulin Sensitivity in Subjects With Pre-diabetes

Conditions:   Diabetes;   Metabolic Syndrome;   Insulin Resistance
Intervention:   Drug: pegvisomant
Sponsors:   University of California, San Francisco;   San Francisco General Hospital
Completed - verified May 2016

Inflammation Inhibition in Prediabetic Humans

Conditions:   Prediabetes;   Obese
Interventions:   Drug: Salsalate;   Drug: Placebo
Sponsor:   University of Iowa
Recruiting - verified May 2016

Evaluation of the Ottawa Model for Smoking Cessation in Diabetes Education Programs

Conditions:   Pre-diabetic;   Diabetic Type II Mellitus
Intervention:   Behavioral: Ottawa Model for Smoking Cessation
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting - verified May 2016

Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to Everolimus/Reduced Tacrolimus in Renal Transplant Recipients Following Campath® Induction

Condition:   Renal Transplant
Intervention:   Drug: Arm 1 Everolimus/Reduced dose tacrolimus
Sponsors:   University of Toledo Health Science Campus;   Novartis Pharmaceuticals
Recruiting - verified May 2016

A Pilot Feasibility Study of Fibroblast Calcium and Glucoregulation in Health and Disease

Condition:   Type 2 Diabetes
Intervention:  
Sponsors:   University of Kentucky;   American Diabetes Association
Active, not recruiting - verified May 2016

Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals

Condition:   Obesity
Intervention:   Drug: Roflumilast
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2016

Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease

Conditions:   Overweight;   Obesity;   Dyslipidemia;   Hyperlipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Gout;   Hypertension;   Metabolic Syndrome;   Coronary Heart Disease;   Cardiovascular Disease
Intervention:  
Sponsors:   John Sievenpiper;   Calorie Control Council;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2016

MAIN STUDY: Low Glycaemic Index (GI) Diet in the Management of GDM SUB-STUDY: The Breast Milk Sub-Study

Condition:   Gestational Diabetes Mellitus
Interventions:   Other: Standard Care;   Other: Low GI diet
Sponsors:   University of Toronto;   Canadian Diabetes Association;   Canadian Institutes of Health Research (CIHR);   Canadian Foundation for Dietetic Research (CFDR)
Completed - verified May 2016

Mifepristone for Metabolic Syndrome

Conditions:   Endocrine Disease;   Diabetes
Intervention:   Drug: Mifepristone
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2016

Postpartum Weight Loss and Exercise (PRIDE)

Conditions:   Gestational Diabetes;   Glucose Intolerance
Interventions:   Behavioral: Non-intervention group;   Behavioral: Face to face;   Behavioral: Telehelath Group
Sponsors:   Pennington Biomedical Research Center;   THE C.B. AND IRENE PENNINGTON FOUNDATION
Recruiting - verified May 2016

Observational Study of the Safety and Efficacy of Norditropin® in Patients With SGA (Small for Gestational Age) Short Stature That Are Still Growing

Conditions:   Foetal Growth Problem;   Small for Gestational Age
Intervention:   Drug: somatropin
Sponsor:   Novo Nordisk A/S
Active, not recruiting - verified December 2015

Treatment of Impaired Glucose Tolerance in Pregnancy

Conditions:   Impaired Glucose Tolerance;   Fetal Macrosomia
Intervention:   Drug: Insulin aspart and Insulin human (isophane)
Sponsors:   University Hospital Orebro;   Uppsala-Örebro Regional Research Council
Completed - verified May 2016

Cross-Sectional and Longitudinal Studies of "Pre-Diabetes" in the Pima Indians

Condition:   Diabetes
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 2016