Clinical Trial Finder

Many patients with prediabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Effect of Resistance Training on Metabolic Control and Outcome in Prediabetes (NMR-based Metabonomics)

Condition:   Prediabetic State
Interventions:   Behavioral: resistance training;   Behavioral: aerobic training
Sponsors:   Nanjing University of Traditional Chinese Medicine;   Guangxi Medical University;   Southeast University, China
Recruiting - verified September 2015

Long-term Resveratrol and Metabolism

Condition:   Pre-diabetes
Interventions:   Dietary Supplement: resveratrol;   Dietary Supplement: placebo
Sponsors:   Maastricht University Medical Center;   Diabetes Fonds;   DSM Nutritional Products, Inc.
Not yet recruiting - verified September 2015

Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients

Conditions:   Diabetes Mellitus, Type 2;   Prediabetic State;   Hypertension;   Prehypertension;   Obesity
Intervention:   Other: FeatForward App (on study smartphone)
Sponsors:   Massachusetts General Hospital;   Samsung Electronics
Enrolling by invitation - verified October 2015

Glucose Tolerance in Children With Cystic Fibrosis

Conditions:   Glucose Intolerance;   Cystic Fibrosis
Intervention:   Other: Diagnostics for glucose tolerance with 3 different methods.
Sponsors:   Christoph Saner;   University Hospital Inselspital, Berne
Recruiting - verified October 2015

Effects of Artificial Sweeteners on Gut Microbiota and Glucose Metabolism

Condition:   Impaired Glucose Tolerance
Interventions:   Other: Sucralose;   Other: Aspartame
Sponsor:   University of Manitoba
Not yet recruiting - verified July 2015

Cut Down on Carbohydrate Usage in the Diet of Type 2 Diabetes - Mechanisms of Effective Therapy of Diabetes by Selective Choice of Macronutrients - The Phenotype Study

Condition:   Type 2 Diabetes
Interventions:   Other: Low carbohydrate meals;   Other: Standard carbohydrate meals
Sponsor:   Bispebjerg Hospital
Recruiting - verified October 2015

Efficacy of Vitamin D Therapy on Glucose Homeostasis in Obese Adolescents

Condition:   Vitamin D Deficiency
Interventions:   Drug: Vitamin D2;   Drug: Placebo
Sponsor:   New York University School of Medicine
Completed - verified October 2015

Designer Functional Foods on Parameters of Metabolic and Vascular in Prediabetes

Condition:   Pre-Diabetes
Interventions:   Dietary Supplement: Functional Ingredient Group;   Dietary Supplement: Control Ingredient Group
Sponsors:   University of Manitoba;   Manitoba Science and Technology International Collaboration Fund ;   Manitoba Agri-Health Research Network
Not yet recruiting - verified October 2015

Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism

Conditions:   Pre-Diabetes;   Major Lung or Abdominal Surgery;   Insulin Resistance
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsors:   McGill University Health Center;   Mitacs;   Medtronic - MITG
Not yet recruiting - verified September 2015

Effect of Dietary Habits on Metabolic Health

Conditions:   Overweight;   Obesity;   Prediabetes;   Meals
Intervention:   Behavioral: Meal schedule
Sponsors:   Brigham and Women's Hospital;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified October 2015

A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH

Condition:   Fatty Liver
Intervention:   Drug: Aramchol
Sponsors:   Galmed Pharmaceuticals Ltd;   Sintesi Research Srl;   Sharp;   Diamond Pharma Services;   CRL;   Fondazione IRCCS Ca;   ClinIntel;   Itamar;   OWL;   Medical University of Gratz, Austria;   Tel-Aviv Sourasky Medical Center
Recruiting - verified October 2015

Dose-dependent Effect of Grape Seed Extract on Glucose Control in People With Impaired Glucose Tolerance

Condition:   Impaired Glucose Tolerance
Interventions:   Dietary Supplement: 0 mg placebo;   Dietary Supplement: 300 mg GSE;   Dietary Supplement: 600 mg GSE;   Dietary Supplement: 900 mg GSE
Sponsor:   Institute for Food Safety and Health, United States
Recruiting - verified October 2015

Effect of Metformin on Disease Progression in Patients With Cryptogenic Cirrhosis (NASH-related Cirrhosis) With Diabetes or Impaired Glucose Tolerance or Insulin Resistance

Condition:   NASH Related Cirrhosis
Interventions:   Drug: Metformin;   Drug: Insulin
Sponsor:   Institute of Liver and Biliary Sciences, India
Recruiting - verified September 2015

Continuous Glucose Monitoring in Controls With and Without Cystic Fibrosis

Condition:   Cystic Fibrosis
Sponsor:   University of Colorado, Denver
Recruiting - verified October 2015

Metformin Treatment in Polycystic Ovary Syndrome (PCOS)

Condition:   Polycystic Ovary Syndrome
Intervention:   Drug: Metformin ER
Sponsors:   Massachusetts General Hospital;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   University of Utah
Recruiting - verified October 2015

Resveratrol and First-degree Relatives of Type 2 Diabetic Patients

Condition:   Pre-diabetes
Interventions:   Dietary Supplement: placebo;   Dietary Supplement: resveratrol
Sponsors:   Maastricht University Medical Center;   DSM Nutritional Products, Inc.;   Diabetes Fonds
Recruiting - verified September 2015

Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis

Conditions:   NAFLD;   Pre-diabetes
Intervention:   Drug: Metadoxine
Sponsor:   Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Recruiting - verified September 2015

Genetics of Latent Autoimmune Diabetes in Adults

Condition:   Latent Autoimmune Diabetes in Adult
Sponsor:   Children's Hospital of Philadelphia
Recruiting - verified October 2015

Effect of Age on Glucose and Lipid Metabolism

Conditions:   Glucose Metabolism Disorders;   Lipid Metabolism Disorders;   Metabolic Diseases
Intervention:   Behavioral: Aerobic Exercise
Sponsors:   The University of Texas Health Science Center at San Antonio;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Active, not recruiting - verified September 2015

Polycystic Ovary Syndrome Genetics and Treatment Response

Condition:   Polycystic Ovary Syndrome
Interventions:   Drug: Metformin ER;   Drug: Metformin
Sponsors:   Massachusetts General Hospital;   American Diabetes Association
Active, not recruiting - verified October 2015

Chronic Sleep Deprivation as a Risk Factor for Metabolic Syndrome and Obesity

Conditions:   Obesity;   Chronic Sleep Deprivation
Intervention:   Procedure: Increase sleep
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Terminated - verified June 2013

Rosiglitazone to Reverse Metabolic Defects in Diabetes

Conditions:   Diabetes Mellitus, Type II;   Insulin Resistance
Interventions:   Procedure: Exercise cardiopulmonary metabolic testing;   Procedure: Skeletal muscle biopsy;   Procedure: Brachial artery reactivity testing
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified September 2008

Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes

Condition:   Congestive Heart Failure
Interventions:   Drug: Avandia (Rosiglitazone);   Drug: Avanclia (Rosiqlitazone)
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2007

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