Prediabetes

Clinical Trial Finder

Many patients with prediabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Effect of Valedia on Glucose and Lipid Homeostasis on Subjects With Prediabetes

Conditions:   Prediabetes;   Type 2 Diabetes;   Hypertriglyceridemia;   Obesity;   Disease;   Insulin Resistance
Interventions:   Dietary Supplement: Valedia;   Dietary Supplement: Placebo
Sponsors:   Valbiotis;   BioFortis
Recruiting - verified August 2016

Effect of Polyherbal Compound for Control of Blood Sugar in Impaired Glucose Tolerance and Diabetes

Condition:   Diabetes Mellitus
Interventions:   Drug: Polyherbal capsule coccinia, bougainvillea, catharanthus;   Drug: Placebo
Sponsor:   Organic India
Not yet recruiting - verified August 2016

Valued EpiGenetic Glycemic ImprovEments Through Weight Loss

Conditions:   Obesity;   Pre-diabetes
Interventions:   Behavioral: Weight Loss Group;   Behavioral: Delayed Weight Loss
Sponsors:   Jingzhong Ding, PhD;   Medifast, Inc.;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting - verified August 2016

Body Composition and White Adipose Tissue Inflammation

Conditions:   Breast Cancer;   Prostate Cancer;   Body Composition;   White Adipose Tissue Inflammation
Interventions:   Device: DEXA Scan;   Behavioral: Godin Leisure Time Exercise Questionnaire (GLTEQ)
Sponsors:   Memorial Sloan Kettering Cancer Center;   Weill Medical College of Cornell University
Recruiting - verified August 2016

The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes

Conditions:   Prediabetic State;   Obesity
Interventions:   Drug: Dapagliflozin;   Drug: Metformin;   Behavioral: Exercise
Sponsors:   Steno Diabetes Center;   The Novo Nordic Foundation;   Rigshospitalet, Denmark;   AstraZeneca;   Bayer
Recruiting - verified August 2016

Evaluation of Prevent in Underserved Populations

Conditions:   Prediabetes;   Overweight;   Obesity
Intervention:   Behavioral: Prevent
Sponsors:   Omada Health, Inc.;   Kresge Foundation;   California HealthCare Foundation;   University of Southern California
Recruiting - verified August 2016

The Relationship Between Advanced Glycation Endproducts and Diabetes

Conditions:   Diabetic Retinopathy;   Type 2 Diabetes Mellitus
Intervention:  
Sponsor:   University of Colorado, Denver
Recruiting - verified August 2016

Cold Induced Changes in White Adipose

Conditions:   Obese;   Normal Body Weight;   Prediabetes;   Metabolic Syndrome
Interventions:   Procedure: Fat biopsy;   Drug: Propranolol and fat biopsy;   Other: heavy water and fat biopsy
Sponsors:   University of Kentucky;   National Institutes of Health (NIH)
Recruiting - verified August 2016

Long-term Resveratrol and Metabolism

Condition:   Pre-diabetes
Interventions:   Dietary Supplement: resveratrol;   Dietary Supplement: placebo
Sponsors:   Maastricht University Medical Center;   Diabetes Fonds;   DSM Nutritional Products, Inc.
Recruiting - verified August 2016

Study of the Reversibility of Glucose Intolerance Caused by Chronic Aspartame Consumption

Condition:   Glucose Metabolism Disorder
Intervention:   Other: Diet soda containing aspartame only
Sponsor:   Rockefeller University
Recruiting - verified August 2016

Bridging Income Generation With Group Integrated Care

Conditions:   Cardiovascular Disease;   Diabetes
Interventions:   Other: Usual Clinical Care;   Other: Group Medical Visits;   Other: Microfinance Groups
Sponsors:   Icahn School of Medicine at Mount Sinai;   Moi University College of Health Sciences;   Brown University;   Duke University;   Purdue University;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified August 2016

Mitochondrial-related Platelet Transcript Expression Levels in Pre-diabetic Subjects Randomized to Metformin or Placebo

Condition:   Prediabetes
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsor:   University of Utah
Recruiting - verified August 2016

Resveratrol and First-degree Relatives of Type 2 Diabetic Patients

Condition:   Pre-diabetes
Interventions:   Dietary Supplement: placebo;   Dietary Supplement: resveratrol
Sponsors:   Maastricht University Medical Center;   DSM Nutritional Products, Inc.;   Diabetes Fonds
Recruiting - verified August 2016

Blood Lipopolysaccharide (LPS) Rifaximin Study

Conditions:   Obese;   Insulin Resistance;   Metabolic Syndrome
Interventions:   Drug: Rifaximin SSD;   Other: Placebo
Sponsors:   Philip Kern;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified August 2016

Metabolic Effects of Betaine Supplementation

Conditions:   Obesity;   Dysglycemia
Interventions:   Drug: Betaine;   Drug: Placebo
Sponsors:   Joslin Diabetes Center;   American Diabetes Association
Recruiting - verified August 2016

Comparison of Time-Restricted Feeding Versus Grazing

Conditions:   Prediabetes;   Insulin Resistance;   Vascular Diseases
Interventions:   Other: Time-Restricted Feeding;   Other: Grazing
Sponsor:   Pennington Biomedical Research Center
Completed - verified August 2016

Effect of Chronic Incretin-based Therapy in Cystic Fibrosis

Conditions:   Cystic Fibrosis;   Pancreatic Insufficiency
Intervention:   Drug: Sitagliptin
Sponsors:   University of Pennsylvania;   Children's Hospital of Philadelphia
Recruiting - verified August 2016

Diabetes Prevention in Clinical Practice.

Condition:   Type 2 Diabetes
Interventions:   Behavioral: Low intensity intervention;   Behavioral: High intensity intervention.
Sponsor:   Göteborg University
Completed - verified August 2016

Effect of Saxagliptin Treatment on Myocardial Fat Content, and Monocyte Inflammation

Condition:   Impaired Glucose Tolerance
Interventions:   Drug: Saxagliptin;   Drug: Placebo
Sponsor:   Baylor College of Medicine
Recruiting - verified August 2016