Clinical Trial Finder

Many patients with prediabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Prohealth@Home: A Feasibility Study Investigating the Use of a Lifestyle App in People at Risk of Type 2 Diabetes

Condition:   Pre-diabetes
Intervention:   Behavioral: Lifestyle counselling
Sponsor:   University of Plymouth
Recruiting - verified May 2015

Rowing Away From Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Glucose Intolerance;   Hyperglycemia
Intervention:   Other: Indoor rowing
Sponsors:   University of Leicester;   Medtronic;   Wellcome Trust
Enrolling by invitation - verified May 2015

Dynamic Responsiveness of Insulin Secretory Parameters To Sitagliptin and Glimeperide Administration in Type 2 DM

Condition:   Type 2 Diabetes
Interventions:   Drug: Glimepiride;   Drug: Sitagliptin;   Drug: Metformin
Sponsors:   Foundation for the National Institutes of Health;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Juvenile Diabetes Research Foundation;   Amylin Pharmaceuticals, LLC.;   Eli Lilly and Company;   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.;   Merck Sharp & Dohme Corp.;   Novartis;   Pfizer;   Takeda
Not yet recruiting - verified May 2015

Research of Intensive Lifestyle Intervention for PCOS Patients With IGT

Conditions:   Polycystic Ovary Syndrome;   Life Style
Interventions:   Behavioral: intensive lifestyle intervention;   Drug: GLP-1 Agonists;   Drug: Metformin;   Drug: Acarbose
Sponsor:   RenJi Hospital
Recruiting - verified May 2015

PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes

Conditions:   Diabetes;   Obesity
Interventions:   Behavioral: Pre-study dietary and exercise instruction.;   Procedure: Screening examination and oral glucose tolerance test;   Procedure: Euglycemic clamp;   Procedure: VO2max.;   Behavioral: Acute exercise bout;   Procedure: Percutaneous needle muscle biopsies
Sponsors:   Mayo Clinic;   Arizona State University
Recruiting - verified May 2015

Study to Evaluate Safety and Efficacy of PreCrea® on Subjects With Higher Than Normal Blood Sugar Levels

Conditions:   Diabetes Mellitus;   Pre-Diabetes;   Hyperglycemia;   Metabolic Syndrome
Interventions:   Dietary Supplement: Study dietary supplement (PreCrea 600 mg capsules);   Dietary Supplement: Placebo
Sponsor:   Joe Fenn
Completed - verified May 2015

Metformin in Co-morbid Diabetes or Prediabetes and Serious Mental Illness

Conditions:   Diabetes Mellitus, Type 2;   Schizophrenia
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsor:   Centre for Addiction and Mental Health
Recruiting - verified May 2015

The Effect of a Nutritional Supplement on Post Prandial Glucose and Lipids in an Adult Population

Condition:   Impaired Fasting Glucose
Interventions:   Dietary Supplement: 25% fibre;   Dietary Supplement: 0% fibre
Sponsor:   GlaxoSmithKline
Completed - verified April 2015

Impact of Sitagliptin on Cardiovascular Exercise Performance in Type 2 Diabetes

Conditions:   Type 2 Diabetes;   Cardiovascular Disease
Interventions:   Drug: Sitagliptin;   Drug: Glimepiride;   Drug: Placebo;   Drug: Placebo
Sponsors:   University of Colorado, Denver;   Merck Sharp & Dohme Corp.
Recruiting - verified December 2014

Non-Alcoholic Fatty Liver Disease in Gestational Diabetes

Condition:   Gestational Diabetes Mellitus in Pregnancy
Interventions:   Other: Subjects with Gestational Diabetes;   Other: Controls without Gestational Diabetes
Sponsor:   University of Florida
Recruiting - verified May 2015

Genetics of Latent Autoimmune Diabetes in Adults

Condition:   Latent Autoimmune Diabetes in Adult
Sponsor:   Children's Hospital of Philadelphia
Recruiting - verified May 2015

Effect of Dietary Glycemic Index on Beta-cell Function

Conditions:   Impaired Glucose Tolerance;   Oxidative Stress;   Prediabetes;   Impaired Fasting Glucose
Interventions:   Other: low glycemic index diet;   Other: high glycemic index diet plus placebo;   Drug: high glycemic index diet plus N-acetylcysteine
Sponsors:   Seattle Institute for Biomedical and Clinical Research;   VA Puget Sound Health Care System
Recruiting - verified May 2015

Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)

Condition:   Atherosclerosis
Interventions:   Drug: Canakinumab;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting - verified May 2015

Metabolic Syndrome in Bone Marrow Transplant Survivors

Condition:   Metabolic Syndrome
Intervention:   Other: Diagnostic exams
Sponsor:   Nationwide Children's Hospital
Terminated - verified May 2015

Effect of Increlex® on Children With Crohn Disease

Condition:   Crohn Disease
Intervention:   Drug: rhIGF (Increlex)
Sponsors:   Nationwide Children's Hospital;   Tercica
Terminated - verified June 2010

Insulin Resistance and Atherosclerosis in Women With Lupus

Conditions:   Systemic Lupus Erythematosus;   Insulin Resistance;   Atherosclerosis
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed - verified May 2015

Losartan Versus Hydrochlorothiazide in Reversing Remodeling of Small Arteries in Pre-Hypertensive Pre-Diabetic Subjects

Conditions:   Pre-hypertension;   Pre-diabetes
Intervention:   Drug: losartan, hydrochlorothiazide
Sponsors:   Sir Mortimer B. Davis - Jewish General Hospital;   Merck Frosst Canada Ltd.
Terminated - verified May 2015

The Metabolic Effects of Almond Consumption in Adults With Pre-Diabetes

Conditions:   Prediabetes;   Insulin Resistance;   Metabolic Syndrome
Interventions:   Behavioral: Almonds in a calorie controlled diet;   Behavioral: Nut free diet
Sponsors:   University of Medicine and Dentistry of New Jersey;   Almond Board of California
Active, not recruiting - verified May 2015

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