Clinical Trial Finder

Many patients with prediabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Hospital-based Diabetes Prevention Study in Korea

Condition:   PreDiabetes
Interventions:   Behavioral: Exercise and Diet remedies;   Drug: Metformin
Sponsors:   Jeong-taek Woo;   National Evidence-Based Healthcare Collaborating Agency;   Kyungpook National University;   Korea University Guro Hospital;   Pusan National University Hospital;   Samsung Medical Center;   Seoul National University Hospital;   Asan Medical Center;   Ajou University School of Medicine;   Severance Hospital;   Chonbuk National University Hospital
Recruiting - verified November 2016

Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease

Conditions:   Mild Cognitive Impairment;   Insulin Resistance
Interventions:   Other: Low carbohydrate diet;   Other: Low fat diet
Sponsor:   Wake Forest School of Medicine
Active, not recruiting - verified December 2016

Relations Between Atherogenic Index of Plasma-Glucose Metabolism

Condition:   Diabetes Mellitus Risk
Sponsor:   Erzincan University
Completed - verified November 2016

Complete Health Improvement Program (CHIP) Risk Reduction/Claims Evaluation Project

Conditions:   Cardiovascular Diseases;   Diabetes Mellitus;   Hypertension;   Dyslipidemias;   Overweight and Obesity
Intervention:   Behavioral: The Complete Health Improvement Program
Sponsors:   Ohio University;   Touro University
Recruiting - verified November 2016

Effect of Valedia on Glucose and Lipid Homeostasis on Subjects With Prediabetes

Conditions:   Prediabetes;   Type 2 Diabetes;   Hypertriglyceridemia;   Obesity;   Disease;   Insulin Resistance
Interventions:   Dietary Supplement: Valedia;   Dietary Supplement: Placebo
Sponsors:   Valbiotis;   BioFortis
Recruiting - verified December 2016

Valued EpiGenetic Glycemic ImprovEments Through Weight Loss

Conditions:   Obesity;   Pre-diabetes
Interventions:   Behavioral: Weight Loss Group;   Behavioral: Delayed Weight Loss
Sponsors:   Jingzhong Ding, PhD;   Medifast, Inc.;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified December 2016

A Trial Investigating Safety, Tolerability, PK and PD for Multiple Doses of NNC9204-0530 in Male and Female Subjects Being Overweight or With Obesity

Condition:   Obesity
Interventions:   Drug: NNC9204-0530;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Recruiting - verified November 2016

Smart Technology for Weight Loss and Metabolic Health

Conditions:   Obesity;   Overweight;   Prediabetes;   Weight Loss;   Lifestyle
Interventions:   Device: Wearable technology, smartscale;   Behavioral: Smartphone applications;   Behavioral: Standard Weight Management Visits
Sponsors:   Temple University;   The Obesity Treatment Foundation
Active, not recruiting - verified December 2016

Effect of Anthocyanins on Metabolic Profiles in Subjects With Pre-diabetes

Conditions:   Insulin Resistance;   Glucose Metabolism Disorders;   Type 2 Diabetes;   Lipid Metabolism Disorders
Interventions:   Dietary Supplement: Anthocyanins;   Dietary Supplement: Placebo
Sponsor:   Sun Yat-sen University
Completed - verified December 2016

A Study to Assess the Effect of a Normal vs. High Protein Diets in Carbohydrates Metabolism in Obese Subjects With Diabetes or Prediabetes

Conditions:   Weight Loss;   Obesity;   Diabetes;   Diet, Reducing;   Carbohydrates;   Protein
Interventions:   Behavioral: Weight loss interventional study with a low-calorie 18%-protein diet;   Behavioral: Weight loss interventional study with a low-calorie 35%-protein diet
Sponsor:   Instituto Aragones de Ciencias de la Salud
Recruiting - verified December 2016

The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients

Condition:   Cystic Fibrosis
Interventions:   Drug: novolog insulin;   Drug: levemir insulin;   Drug: placebo
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Children's Hospitals and Clinics of Minnesota
Recruiting - verified November 2016

Effects of Lignan-rich Diet on Cardiometabolic Risk Factors

Conditions:   Metabolic Syndrome;   Overweight;   Central Obesity;   Impaired Glucose Tolerance
Interventions:   Other: Whole-grain rye, high lignan;   Other: Whole-grain wheat, low lignan
Sponsor:   Swedish University of Agricultural Sciences
Completed - verified December 2016

Prebiotics, Gut Microbiota, and Cardiometabolic Health

Condition:   Prediabetes
Interventions:   Dietary Supplement: Inulin;   Dietary Supplement: Placebo
Sponsor:   Virginia Polytechnic Institute and State University
Recruiting - verified December 2016

Macronutrient Effects on Alzheimer's Disease (MEAL-2)

Conditions:   Prediabetic State;   Insulin Resistance;   Middle Age;   Prehypertension;   Mild Cognitive Impairment
Interventions:   Other: Low Diet;   Other: High Diet
Sponsor:   Wake Forest School of Medicine
Completed - verified November 2016

The Effects of Apple Consumption on Cardiovascular Health in Prediabetics and Type 2 Diabetics

Conditions:   Diabetes;   Cardiovascular Diseases;   Prediabetes
Interventions:   Dietary Supplement: Apple;   Dietary Supplement: Placebo
Sponsors:   Florida State University;   U.S. Apple Association
Completed - verified December 2016

Comparing Glycaemic Benefits of Active Versus Passive Lifestyle Intervention in Kidney Allograft Recipients

Conditions:   Post Transplantation Diabetes Mellitus;   Obesity;   Transplantation of Kidney
Interventions:   Behavioral: Active lifestyle intervention;   Other: Control
Sponsor:   University Hospital Birmingham NHS Foundation Trust
Recruiting - verified November 2016

Weight Loss and/or Exercise Training to Discover Muscle Lipids Related to Insulin Sensitivity

Conditions:   Diabetes;   Pre-diabetes
Intervention:   Behavioral: Weight loss and exercise training
Sponsors:   University of Colorado, Denver;   American Diabetes Association
Recruiting - verified December 2016

Effect of Saxagliptin Treatment on Myocardial Fat Content, and Monocyte Inflammation

Condition:   Impaired Glucose Tolerance
Interventions:   Drug: Saxagliptin;   Drug: Placebo
Sponsor:   Baylor College of Medicine
Recruiting - verified November 2016

Mifepristone for Metabolic Syndrome

Conditions:   Endocrine Disease;   Diabetes
Intervention:   Drug: Mifepristone
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2016

Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)

Condition:   Atherosclerosis
Interventions:   Drug: Canakinumab;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting - verified December 2016

Study of Oral Anthocyanins on Insulin Resistance

Condition:   Type 2 Diabetes
Intervention:   Dietary Supplement: Mirtoselect
Sponsor:   University of Aberdeen
Recruiting - verified December 2016

Metabolic Syndrome and Functional Food

Condition:   Metabolic Syndrome
Interventions:   Dietary Supplement: P1&P2;   Dietary Supplement: P1&CC;   Dietary Supplement: AG&P2;   Dietary Supplement: AG&CC;   Dietary Supplement: TA (concentrated 5:1 aloe vera gel);   Dietary Supplement: P3
Sponsor:   Universidad Autonoma de Nuevo Leon
Completed - verified July 2009

Cardiovascular Disease Study

Condition:   Spinal Cord Injury
Interventions:   Procedure: 2 hour Oral Glucose Tolerance Test;   Procedure: Fat Meal Test
Sponsors:   VA Office of Research and Development;   Kessler Foundation
Recruiting - verified December 2016