Clinical Trial Finder

Many patients with prediabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Low-Carbohydrate Diabetes Prevention Program

Condition:   PreDiabetes
Intervention:   Behavioral: Low-Carbohydrate Diabetes Prevention Program
Sponsors:   University of Michigan;   National Kidney Foundation of Michigan
Not yet recruiting - verified August 2017

Diabetes Prevention With Lifestyle Intervention and Metformin Escalation

Condition:   Diabetes
Interventions:   Drug: Metformin Escalation;   Behavioral: Lifestyle Intervention
Sponsor:   Yale University
Not yet recruiting - verified August 2017

Evaluating the Implementation of the Diabetes Prevention Program in an Integrated Health System

Condition:   Diabetes
Intervention:   Behavioral: Medicare DPP
Sponsor:   Kaiser Permanente
Active, not recruiting - verified August 2017

The Effects of Citric and Malic Acid Found in Pomegranate Juice on Glycaemic Response to White Bread.

Condition:   Hyperglycemia, Postprandial
Interventions:   Other: Control;   Other: Test
Sponsor:   University of Leeds
Active, not recruiting - verified August 2017

The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study

Condition:   Cognitive Impairment
Interventions:   Behavioral: Aerobic Training;   Behavioral: Resistance Training;   Behavioral: Balance and Tone Training
Sponsor:   Western University, Canada
Not yet recruiting - verified August 2017

Effects of Cinnamon Supplementation on Glucose Metabolism in Patients With Pre-diabetes

Conditions:   Dysglycemia;   Obesity
Interventions:   Dietary Supplement: Cinnamon;   Other: placebo
Sponsors:   Joslin Diabetes Center;   Kyunghee University
Recruiting - verified August 2017

Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes

Conditions:   Metabolic Syndrome;   PreDiabetes
Interventions:   Other: USDA Style Diet;   Other: Lean Beef Diet
Sponsors:   Midwest Center for Metabolic and Cardiovascular Research;   National Cattlemen's Beef Association
Recruiting - verified June 2017

Integrated Community-Clinical Linkage Model to Promote Weight Loss Among South Asians With Pre-Diabetes

Conditions:   Pre Diabetes;   Weight Loss
Intervention:   Other: community health worker (CHW)-led health coaching for patients
Sponsor:   New York University School of Medicine
Not yet recruiting - verified August 2017

PRuDENTE; Diabetes Prevention Via Exercise, Nutrition and Treatment

Conditions:   Diabetes Mellitus, Type 2;   Prediabetic State
Interventions:   Drug: Metformin;   Behavioral: Lifestyle intervention
Sponsors:   Instituto Nacional de Salud Publica, Mexico;   Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran;   Ministry of Health, Mexico City;   University of California, San Francisco
Recruiting - verified June 2017

Peanut Consumption and Cardiovascular Disease Risk in a Chinese Population

Condition:   T2D
Interventions:   Dietary Supplement: Peanut;   Dietary Supplement: Control
Sponsor:   Harvard School of Public Health
Recruiting - verified August 2017

Effects of Almonds on Insulin Sensitivity in Prediabetes

Condition:   PreDiabetes
Interventions:   Other: 1.5 oz of whole, natural almonds;   Other: Low-fat, high refined starches/sugars
Sponsors:   Midwest Center for Metabolic and Cardiovascular Research;   Almond Board of California
Recruiting - verified April 2017

Cardiovascular Health Promotion Among African-Americans by FAITH!

Conditions:   Cardiovascular Diseases;   Prevention;   Physical Activity;   Diet Modification;   Diabetes;   Hypertension;   High Cholesterol;   Pre Diabetes;   Smoking Cessation;   Obesity
Intervention:   Behavioral: FAITH! App digital intervention
Sponsors:   Mayo Clinic;   Mayo Clinic Clinic Center for Innovation;   Mayo Clinic Center for Clinical and Translational Science (CCaTS)
Active, not recruiting - verified August 2017

Effectiveness and Safety Study of the Percutaneous Optical Fibre Glucose Sensor (FiberSense)

Condition:   Diabetes Mellitus
Interventions:   Device: FiberSense sensor;   Device: Dexcom Sensor
Sponsor:   Lee's Pharmaceutical Limited
Not yet recruiting - verified August 2017

A Study of EDP 305 in Healthy Subjects and Subjects With Presumptive NAFLD

Condition:   Presumptive NAFLD
Interventions:   Drug: EDP 305;   Drug: Placebo
Sponsors:   Enanta Pharmaceuticals;   Pharmaceutical Research Associates
Completed - verified August 2017

Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes

Conditions:   Prediabetes;   Hyperglycemia;   Postprandial Hyperglycemia;   Impaired Glucose Tolerance;   Impaired Fasting Glucose
Interventions:   Other: Sweetch App + DBWS;   Other: Sweetch App Alone
Sponsors:   Johns Hopkins University;   Sweetch Health, Ltd
Active, not recruiting - verified August 2017

Prevention of Type 2 Diabetes Amongst South Asians With Central Obesity and Prediabetes

Condition:   Type 2 Diabetes
Intervention:   Behavioral: Intensive lifestyle modification
Sponsors:   Imperial College London;   London North West Healthcare NHS Trust
Recruiting - verified August 2016

Smart Technology for Weight Loss and Metabolic Health

Conditions:   Obesity;   Overweight;   Prediabetes;   Weight Loss;   Lifestyle
Interventions:   Device: Wearable technology, smartscale;   Behavioral: Smartphone applications;   Behavioral: Standard Weight Management Visits
Sponsors:   Temple University;   The Obesity Treatment Foundation
Active, not recruiting - verified August 2017

Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

Conditions:   Diabetes Mellitus, Type 2;   Impaired Glucose Tolerance (IGT);   Impaired Fasting Glucose (IFG)
Interventions:   Drug: Dapagliflozin;   Drug: Saxagliptin;   Drug: Pioglitazone;   Drug: Metformin
Sponsors:   The University of Texas Health Science Center at San Antonio;   American Diabetes Association;   AstraZeneca
Recruiting - verified August 2017

Interventional Bioremediation of Microbiota in Metabolic Syndrome

Condition:   Pre-Diabetes
Interventions:   Drug: Vancomycin;   Other: Placebo;   Drug: Neomycin;   Drug: Clindamycin;   Procedure: Fecal Microbiota Transplantation
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Active, not recruiting - verified August 2017

Evaluation of Prevent in Underserved Populations

Conditions:   Prediabetes;   Overweight;   Obesity
Intervention:   Behavioral: Prevent
Sponsors:   Omada Health, Inc.;   Kresge Foundation;   California HealthCare Foundation;   University of Southern California
Active, not recruiting - verified August 2017

ORION: Effects of Cenicriviroc on Insulin Sensitivity in Subjects With Prediabetes or T2DM and Suspected NAFLD

Conditions:   Prediabetic State;   Non-alcoholic Fatty Liver Disease;   Type 2 Diabetes Mellitus
Interventions:   Drug: Cenicriviroc 150 mg;   Drug: Matching placebo
Sponsor:   Tobira Therapeutics, Inc.
Completed - verified August 2017

Individualized Lifestyle Intervention in Subjects With Prediabetes

Condition:   Diabetes Mellitus Type 2
Interventions:   Behavioral: intensified lifestyle intervention;   Behavioral: normal lifestyle intervention;   Behavioral: Single lifestyle advice
Sponsors:   University Hospital Tuebingen;   German Diabetes-Center, Leibniz-Institut in Düsseldorf;   Endocrinology and Metabolic Diseases, Charité Berlin;   German Institute of Human Nutrition;   University Hospital Carl Gustav Carus;   LMU München, medical clinic IV;   University Hospital Heidelberg
Completed - verified August 2017

The Role of Non-Alcoholic Fatty Liver Disease in Gestational Diabetes

Condition:   Gestational Diabetes Mellitus in Pregnancy
Interventions:   Other: Subjects with Gestational Diabetes;   Other: Controls without Gestational Diabetes
Sponsor:   University of Florida
Active, not recruiting - verified August 2017

Metformin and Muscle in Insulin-resistant Older Veterans

Condition:   Prediabetes
Interventions:   Drug: metformin;   Drug: placebo
Sponsors:   VA Office of Research and Development;   Oregon Health and Science University
Active, not recruiting - verified August 2017

Cinnamon Trial-lIfestyle iNtervention Plus Water-soluble Cinnamon Extract On loweriNg Blood Glucose in Pre-diabetics

Conditions:   Diabetes;   Pre-Diabetes
Intervention:   Drug: water-soluble cinnamon extract (Cinnulin PF)
Sponsor:   Mike O'Callaghan Federal Hospital
Suspended - verified August 2017

Postpartum Weight Loss and Exercise (PRIDE)

Conditions:   Gestational Diabetes;   Glucose Intolerance
Interventions:   Behavioral: Non-intervention group;   Behavioral: Face to face;   Behavioral: Telehelath Group
Sponsors:   Pennington Biomedical Research Center;   THE C.B. AND IRENE PENNINGTON FOUNDATION
Active, not recruiting - verified August 2017