Peripheral Artery Disease and Your Heart

Clinical Trial Finder

Many patients with type 2 diabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Evaluation of the Impact of Intensive Short-Term Drug Therapy in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Diabetes mellitus Type 2 De-escalation treatment (DET)
Sponsors:   Sciema UG;   Innovative Diabetes Treatment Studies LLC.
Recruiting

Decreasing Stress in Type 2 Diabetes

Conditions:   Stress;   Diabetes Mellitus, Type 2
Interventions:   Behavioral: Mindfulness Based Stress Reduction;   Behavioral: Stress Management Education
Sponsors:   Milton S. Hershey Medical Center;   Rowan University;   Penn State University;   National Institutes of Health (NIH);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting

Genetics of Type 2 Diabetes Among Han Chinese

Conditions:   Diabetes;   Hypertension
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Completed

Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D™ in Obese Subjects With Type 2 Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Insulin Resistance
Intervention:   Device: HydraSolve T2D™
Sponsor:   Medality Medical
Recruiting

Validation of Machine Learning Based Personalized Nutrition Algorithm to Reduce Postprandial Glycemic Excursions Among North American Individuals With Newly Diagnosed Type 2 Diabetes

Condition:   Type2 Diabetes
Interventions:   Device: iPro2 CGM with Enlite sensors;   Behavioral: LifeStyle
Sponsor:   NYU Langone Health
Recruiting

A Study of Insulin Glargine (LY2963016) in Adult Participants With Type 2 Diabetes in India

Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: Insulin Glargine
Sponsor:   Eli Lilly and Company
Not yet recruiting

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)

Condition:   Type 2 Diabetes
Interventions:   Drug: Tirzepatide;   Drug: Insulin Glargine
Sponsor:   Eli Lilly and Company
Not yet recruiting

The Long-term Effects of an Intensive Lifestyle Intervention for Type 2 Diabetes on Medicare Outcomes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Behavioral: Intensive lifestyle intervention;   Behavioral: Diabetes support and education
Sponsors:   University of Minnesota;   University of Southern California;   Wake Forest University
Active, not recruiting

A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Drug: Tirzepatide;   Drug: Semaglutide
Sponsor:   Eli Lilly and Company
Recruiting

A Study of LY900014 Compared to Insulin Lispro (Humalog) in Adults With Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: LY900014;   Drug: Insulin Lispro;   Drug: Insulin Glargine;   Drug: Insulin Degludec
Sponsor:   Eli Lilly and Company
Recruiting

Effect of 2-Week Nightly Moderate Hypoxia on Glucose Tolerance in Individuals With Type 2 Diabetes

Condition:   Type 2 Diabetes
Intervention:   Device: Hypoxico Altitude Training Systems
Sponsor:   Pennington Biomedical Research Center
Active, not recruiting

Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Other: Bed Rest Intervention;   Other: Resistance Exercise Program
Sponsor:   Translational Research Institute for Metabolism and Diabetes, Florida
Not yet recruiting

Safety and Efficacy of SPIL1033 in Subjects With Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: SPIL1033, Placebo
Sponsor:   Sun Pharmaceutical Industries Limited
Completed

A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Tirzepatide;   Drug: Insulin Degludec
Sponsor:   Eli Lilly and Company
Recruiting

Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Rebaudioside A;   Drug: Placebo
Sponsor:   Universitaire Ziekenhuizen Leuven
Recruiting

A Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Drug: Dulaglutide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting

Comparative Evaluation of the Evolution of Arterial and Microcirculatory Endothelial Function in Obese Patients With Type-2 Diabetes Versus Non-diabetic Obese Patients After a First Bariatric Surgery

Conditions:   Bariatric Surgery;   Obese;   Type2 Diabetes
Interventions:   Biological: Vascularly biological assessment;   Biological: Analysis of vasomotor endothelial function;   Biological: Analysis of arterial compliance;   Biological: Exploration of microcirculation;   Biological: Venous Doppler Ultrasound;   Biological: Arterial pressure measurement;   Biological: Intima-Media Thickness measurement;   Biological: Exploration of neuropathy;   Behavioral: level of physical activity
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Recruiting

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Tirzepatide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting

A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Tirzepatide;   Drug: Insulin Glargine
Sponsor:   Eli Lilly and Company
Recruiting

Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy Study

Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Abnormal Glucose Metabolism;   Type 2 Diabetes
Intervention:   Behavioral: Assignment of a Lay Patient Partner
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

A Study of People With Type 2 Diabetes Who Have Diseases That Affect the Heart and Blood Vessels. The Study Will Also Look at the Treatment of a Group of These People in Hospitals in Portugal

Condition:   Diabetes Mellitus, Type 2
Intervention:   Other: No treatment given
Sponsor:   Novo Nordisk A/S
Completed

Effect of Sotagliflozin on Cardiovascular Events in Patients With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Condition:   Heart Failure-Type 2 Diabetes Mellitus
Interventions:   Drug: Sotagliflozin (SAR439954);   Drug: Placebo
Sponsor:   Sanofi
Recruiting

Glycemic Response of Bean-and-rice Meals in Type 2 Diabetes Mellitus

Conditions:   Blood Glucose;   Type 2 Diabetes Mellitus
Intervention:   Other: Whole cooked beans with rice meals
Sponsors:   Arizona State University;   United States Dry Bean Council
Completed

Efficacy and Safety of Liraglutide in Type 2 Diabetes With Lower Extremity Arterial Disease

Conditions:   Type 2 Diabetes;   Peripheral Vascular Disorder Due to Diabetes Mellitus
Interventions:   Drug: Liraglutide+standard-of-care treatment;   Other: standard-of-care treatment
Sponsor:   Second Affiliated Hospital, School of Medicine, Zhejiang University
Not yet recruiting

A Study With NLY01 in Subjects With Type 2 Diabetes

Conditions:   Type2 Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: NLY01;   Drug: Placebo
Sponsor:   Neuraly, Inc.
Recruiting

To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD8233 After Multiple Dose Administration in Subjects With Type 2 Diabetes.

Conditions:   Dyslipidemia;   Type 2 Diabetes
Interventions:   Drug: AZD8233 subcutaneous injection;   Drug: Placebo
Sponsors:   AstraZeneca;   Parexel
Not yet recruiting

A Study to Evaluate Safety and Effects of Sotagliflozin Dose 1 and Dose 2 on Glucose Control in Patients With Type 2 Diabetes, Severe Impairment of Kidney Function and Inadequate Blood Sugar Control

Condition:   Type 2 Diabetes Mellitus-Chronic Kidney Disease Stage 4
Interventions:   Drug: Placebo;   Drug: Sotagliflozin (SAR439954)
Sponsor:   Sanofi
Active, not recruiting

Guide To Goals: A Novel Care Coordination Tool for Children With Type Two Diabetes (T2D)

Condition:   Type2 Diabetes Mellitus
Interventions:   Behavioral: Patient and/or Family Member Intervention;   Behavioral: Certified Diabetes Educator Intervention;   Behavioral: Physician Intervention;   Behavioral: Front Desk Staff Intervention;   Behavioral: Nurse Intervention
Sponsors:   Georgia Institute of Technology;   Emory University
Recruiting

SoLaHmo Radio Stories About Children's Healthy Eating and Exercise

Condition:   Type 2 Diabetes
Interventions:   Behavioral: Radio Story;   Behavioral: Audio brochure
Sponsors:   University of Minnesota;   West Side Community Health Services
Completed

Effect of Sotagliflozin on Cardiovascular and Renal Events in Patients With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk

Conditions:   Type 2 Diabetes Mellitus;   Chronic Kidney Diseases
Interventions:   Drug: Sotagliflozin (SAR439954);   Drug: Placebo
Sponsor:   Sanofi
Recruiting

Data Acquisition Study in Inadequately Balanced Patients With Type 2 Diabetes Mellitus

Condition:   Type2 Diabetes
Intervention:   Device: data collection
Sponsors:   ValoTec;   APHP
Recruiting

Diabetes Prevention Using SMS Technology

Condition:   Prediabetes
Intervention:   Other: Short text messages
Sponsors:   Imperial College London;   Barts & The London NHS Trust;   Basildon and Thurrock University Hospitals NHS Foundation Trust;   Lister Hospital;   Torbay Hospital;   Queen Alexandra Hospital;   East Surrey Hospital;   Pennine Acute Hospitals NHS Trust;   West Suffolk Hospital;   Derriford Hospital;   Exeter Hospital;   Milton Keynes University Hospital NHS Foundation Trust;   Royal Cornwall Hospitals Trust;   Queen Margaret Hospital, Dunfermline;   Harrogate & District NHS Foundation Trust;   Royal Berkshire NHS Foundation Trust;   Rotherham NHS Trust
Completed

A Research Study, Looking at How Xultophy® Works in People With Type 2 Diabetes in Local Clinical Practice in United Arab Emirates

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Insulin degludec/liraglutide
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric Participants. (MK-0431-083)

Conditions:   Diabetes Mellitus;   Type 2 Diabetes
Interventions:   Drug: Sitagliptin;   Drug: Metformin;   Drug: Placebo to sitagliptin;   Drug: Placebo to metformin;   Drug: Glycemic Rescue 1;   Biological: Glycemic Rescue 2
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin 5 mg;   Drug: Ertugliflozin 15 mg;   Drug: Placebo;   Biological: Insulin;   Drug: Metformin
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Recruiting

RESILIENT: A Research Study, Looking at How Ryzodeg® Works in People With Type 2 Diabetes in Local Clinical Practice in Japan

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Insulin Degludec/Insulin Aspart
Sponsor:   Novo Nordisk A/S
Active, not recruiting

Evaluation of Insulin Glargine/Lixisenatide Fixed Ratio Combination in Patients With Type 2 Diabetes Insufficiently Controlled With Oral Antidiabetic Drug(s)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Insulin glargine/Lixisenatide (HOE901/AVE0010);   Drug: Insulin glargine (HOE901);   Drug: Lixisenatide (AVE0010);   Drug: Metformin
Sponsor:   Sanofi
Recruiting

Creatine for Treatment of Depression Associated With Type 2 Diabetes

Condition:   Major Depressive Disorder
Intervention:   Drug: Creatine Monohydrate
Sponsor:   University of Utah
Recruiting

Effect of VeSTAL Device in Type 2 Diabetes Mellitus

Conditions:   Type 2 Diabetes;   Metabolic Syndrome
Interventions:   Device: Vestal Device;   Device: Placebo device
Sponsors:   Neurovalens Ltd.;   Compliance Solutions Ltd;   University College Dublin;   Exploristics Ltd
Not yet recruiting

Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes Mellitus

Conditions:   Obesity;   Overweight;   Diabetes Mellitus, Type 2
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Genetics of Type 2 Diabetes in West Africans

Conditions:   Hypertension;   Diabetes
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting

A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Liraglutide in the Occurrence of Serious Cardiovascular Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Empagliflozin;   Drug: Liraglutide
Sponsor:   Boehringer Ingelheim
Active, not recruiting

Fenofibrate in Type 2 Diabetes

Condition:   Diabetes Mellitus, Type II
Intervention:   Drug: Fenofibrate
Sponsor:   Medical University of South Carolina
Recruiting

Dapagliflozin Effects on Epicardial Fat

Condition:   Type 2 Diabetes
Interventions:   Drug: Dapagliflozin;   Drug: Metformin
Sponsor:   University of Miami
Active, not recruiting

Family Health Team High-Intensity Interval Training

Condition:   Type 2 Diabetes
Interventions:   Other: High-Intensity Interval Training Physical Activity (PA) Advice;   Other: Population-Based Physical Activity (PA) Advice
Sponsors:   Western University, Canada;   East Elgin Family Health Team
Not yet recruiting

Adaptation of a Digital Weight Loss Intervention Promoting Self-regulation for Use in Type 2 Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Overweight and Obesity
Intervention:   Behavioral: Behavioral weight loss with digital tools
Sponsor:   University of North Carolina, Chapel Hill
Recruiting

Effect of Efpeglenatide on Cardiovascular Outcomes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Efpeglenatide (SAR439977);   Drug: Placebo
Sponsor:   Sanofi
Active, not recruiting

A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Placebo (semaglutide)
Sponsor:   Novo Nordisk A/S
Recruiting

A Study to Observe the Effectiveness of Empagliflozin, Other SGLT-2 Inhibitors, or DPP-4 Inhibitors in Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Subjects treated with Empagliflozin or any Sodium-glucose cotransporter-2 (SGLT-2) inhibitor;   Drug: Subjects treated with Dipeptidyl peptidase-4 (DPP-4) inhibitor
Sponsor:   Boehringer Ingelheim
Active, not recruiting

A Study of LY3305677 in Participants With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: LY3305677;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting

A Research Study, Looking at How Tresiba® Works in People With Type 2 Diabetes in Local Clinical Practice in Saudi Arabia

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Insulin degludec
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

Study of Real-world Evidence With SGLT2i (Dapagliflozin) and DPP4i (Sitagliptin) in Type 2 Diabetes Patients in Spain

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Dapagliflozin;   Drug: Sitagliptin
Sponsors:   Fundación Pública Andaluza para la gestión de la Investigación en Sevilla;   AstraZeneca
Completed

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Placebo
Sponsor:   Novo Nordisk A/S
Recruiting

Using Early Time Restricted Feeding and Timed Light Therapy to Improve Glycemic Control in Adults With Type 2 Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Time Restricted Feeding;   Light; Therapy, Complications
Interventions:   Behavioral: No change in meal timing;   Behavioral: No change in light exposure;   Behavioral: Early Time-Restricted Feeding;   Behavioral: Timed Light Therapy
Sponsor:   University of Alabama at Birmingham
Not yet recruiting

A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus

Conditions:   Diabetes Mellitus, Type 2;   Hypoglycemia
Interventions:   Drug: Tirzepatide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Not yet recruiting

A Study of LY3437943 in Participants With Type 2 Diabetes Mellitus (T2DM)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: LY3437943;   Drug: Dulaglutide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Not yet recruiting

Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: liraglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Completed

A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes.

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: BI 456906;   Drug: Placebo;   Drug: Semaglutide
Sponsor:   Boehringer Ingelheim
Not yet recruiting

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Placebo (semaglutide)
Sponsor:   Novo Nordisk A/S
Recruiting

A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Oral semaglutide;   Drug: Sitagliptin;   Drug: Placebo (oral semaglutide);   Drug: Placebo (sitagliptin)
Sponsor:   Novo Nordisk A/S
Recruiting

Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: oral placebo
Sponsor:   Novo Nordisk A/S
Completed

A Research Study Comparing a New Medicine Oral Semaglutide to Placebo in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Oral semaglutide;   Drug: Placebo
Sponsor:   Novo Nordisk A/S
Recruiting

A Trial Investigating the Safety, Tolerability, Pharmacokinetics (the Exposure of the Trial Drug in the Body) and Pharmacodynamics (the Effect of the Investigated Drug on the Body) of Insulin 287 in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: insulin 287;   Drug: placebo;   Drug: insulin degludec
Sponsor:   Novo Nordisk A/S
Completed

Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Standard of care
Sponsor:   Novo Nordisk A/S
Recruiting

A Research Study to Compare Insulin 287 Once a Week to Insulin Glargine (100 Units/mL) Once a Day in People With Type 2 Diabetes.

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Insulin 287;   Drug: Placebo (insulin 287);   Drug: Metformin;   Drug: Dipeptidyl peptidase-4 inhibitors;   Drug: Insulin glargine;   Drug: Placebo (insulin glargine)
Sponsor:   Novo Nordisk A/S
Active, not recruiting

Imagine to Remember: Improving Medication Adherence in Pre- and Type 2 Diabetes

Condition:   Medication Adherence
Intervention:   Behavioral: Episodic Future Thinking
Sponsor:   State University of New York at Buffalo
Recruiting

A Research Study to Compare Semaglutide to Insulin Aspart, When Taken Together With Metformin and Insulin Glargine, in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Insulin aspart;   Drug: Insulin glargine U100
Sponsor:   Novo Nordisk A/S
Recruiting

A Research Study to Compare the Effect of Insulin Degludec and Insulin Glargine on Blood Sugar Levels in People With Type 2 Diabetes - the SWITCH PRO Study

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Insulin degludec;   Drug: Insulin glargine
Sponsor:   Novo Nordisk A/S
Active, not recruiting

A Multiple Ascending Dose Study to Evaluate Safety and Tolerability of BFKB8488A in Participants With Type 2 Diabetes Mellitus and Participants With Non-Alcoholic Fatty Liver Disease

Conditions:   Diabetes Mellitus, Type 2;   Non-Alcoholic Fatty Liver Disease
Interventions:   Drug: BFKB8488A;   Other: Placebo
Sponsor:   Genentech, Inc.
Active, not recruiting

Managing Type 1 and High Risk Type 2 Diabetes in the Hospital Setting: Glucose as a Vital Sign (Pilot)

Conditions:   Diabetes Mellitus, Type 1;   Diabetes Mellitus, Type 2
Intervention:   Device: Real-time CGM data
Sponsor:   Scripps Whittier Diabetes Institute
Recruiting

DIA_CENTRAL:T2D Treatment Pattern in Central Europe

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Empagliflozin;   Drug: Sodium Glucose Transporter 2 inhibitor;   Drug: Dipeptidyl-peptidase 4 inhibitor;   Drug: Glucagon-like peptide 1 agonist
Sponsor:   Boehringer Ingelheim
Active, not recruiting

Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Insulin

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Completed

A Research Study to Compare Two Doses of Semaglutide Taken Once Weekly in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Placebo (semaglutide)
Sponsor:   Novo Nordisk A/S
Recruiting

A Sleep Intervention (SLEEP-Extend) for Young Adults At-Risk for Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Behavioral: SLEEP-Extend intervention;   Other: Control
Sponsors:   Emory University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

A Study to Look at How Safe NNC0268-0965 is in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: NNC0268-0965;   Drug: insulin glargine
Sponsor:   Novo Nordisk A/S
Recruiting

Pulsatile Insulin Infusion Therapy in Patients With Type 1 and Type 2 Diabetes Mellitus

Conditions:   Diabetes Mellitus, Type 2;   Diabetes Mellitus, Type 1
Interventions:   Drug: 3 hours humulin R 100 IU/mL PIT;   Drug: 2 hours humulin R 100 IU/mL PIT
Sponsors:   Sciema UG;   Innovative Diabetes Treatment Studies LLC.
Recruiting

Impact of a Multidisciplinary Therapeutic Education Program Being Set up for Patients With Type 2 Diabetes Mellitus

Conditions:   Diabetes Mellitus, Type 2;   Patient Education as Topic
Intervention:   Other: Treatment adequacy score
Sponsor:   Groupe Hospitalier Pitie-Salpetriere
Completed

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in France, as Part of Local Clinical Practice (SURE FRANCE)

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: semaglutide
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in United Kingdom, as Part of Local Clinical Practice (SURE UK)

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Semaglutide
Sponsor:   Novo Nordisk A/S
Active, not recruiting

A Research Study, Looking at How Ryzodeg® (Insulin Degludec/Insulin Aspart) Works in People With Type 2 Diabetes in Local Clinical Practice

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Insulin Degludec/Insulin Aspart
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

Comparative Effectiveness of Empagliflozin in the US

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Empagliflozin;   Drug: DPP-4 inhibitor
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Active, not recruiting

STAR Study Investigating Performance and Safety of the Medical Device SiPore15™

Conditions:   PreDiabetes;   Pre Diabetes;   Prediabetic State;   Type2 Diabetes;   Type2 Diabetes Mellitus;   Overweight;   Obese
Intervention:   Device: SiPore15™
Sponsor:   Sigrid Therapeutics AB
Completed

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Spain, as Part of Local Clinical Practice

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Semaglutide
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

Pharmacokinetics, Safety and Tolerability of CKD-387 10/500mg BE Phase1

Condition:   Type2 Diabetes Mellitus
Interventions:   Drug: Part A, Reference (D635 10/500mg, Astrazeneca);   Drug: Part B, Reference (D635 10/500mg, Astrazeneca)
Sponsor:   Chong Kun Dang Pharmaceutical
Completed

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY1142524 in Patients With Type II Diabetes and a Clinical Diagnosis of Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Fulacimstat (BAY1142524);   Drug: Placebo
Sponsor:   Bayer
Completed

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Switzerland, as Part of Local Clinical Practice (SURE SWITZERLAND)

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Semaglutide
Sponsor:   Novo Nordisk A/S
Active, not recruiting

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Denmark and Sweden, as Part of Local Clinical Practice (SURE DENMARK/SWEDEN)

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Semaglutide
Sponsor:   Novo Nordisk A/S
Active, not recruiting

Role of Allopurinol on Oxidative Stress and Mitochondrial Alterations in Skeletal Muscle of Diabetic Patients

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: 2 capsules of allopurinol 150 mg daily for 3 month;   Drug: 2 capsules of lactose daily for 3 month
Sponsor:   Hospices Civils de Lyon
Completed

An Investigation Into The Anti-hypertensive And Potential Anti-inflammatory Actions Of Dapagliflozin

Condition:   Type 2 Diabetes
Interventions:   Drug: dapagliflozin;   Drug: Placebo
Sponsors:   University at Buffalo;   Kaleida Health
Completed

i-Matter: Investigating an mHealth Texting Tool for Embedding Patient-reported Data Into Diabetes Management

Condition:   Type2 Diabetes
Interventions:   Behavioral: MJS Diabetes;   Behavioral: Usual Care
Sponsor:   NYU Langone Health
Recruiting

Efficacy of ACE Inhibitors, MRAs and ACE Inhibitor/ MRA Combination

Conditions:   Diabetic Nephropathy Type 2;   Microalbuminuria Due to Type 2 Diabetes Mellitus
Intervention:   Drug: Tritace (Ramipril 10 mg)
Sponsor:   Beni-Suef University
Recruiting

A Study Based on Data From German Registries That Looks at Characteristics of People Who Take the Medicine Empagliflozin for Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Empagliflozin
Sponsor:   Boehringer Ingelheim
Active, not recruiting

Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 Diabetes

Conditions:   Obesity;   Diabetes
Interventions:   Other: Quercetin;   Other: Placebo
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Post-authorization Safety Study in Type 2 Diabetic Patients in Saudi Arabia Treated With Empagliflozin to Assess the Incidence of Ketoacidosis, Severe Complications of Urinary Tract Infection, Volume Depletion, and Dehydration

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Empagliflozin;   Drug: Dipeptidyl-peptidase 4 (DPP-4) inhibitors
Sponsor:   Boehringer Ingelheim
Recruiting

Phase 2a Study to Evaluate the Safety and Efficacy of PH100 Tablet in T2DM Patients With Recent Cardiovascular

Condition:   Type 2 Diabetes Mellitus With Circulatory Complciation
Intervention:   Drug: Ecklonia cava Phlorotannin
Sponsor:   Bota Bio Co., Ltd.
Completed

Study of Sulphonylurea Synergy With Incretins

Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: Gliclazide
Sponsors:   University of Dundee;   NHS Tayside
Active, not recruiting

Study of the Psychological Profile of Type 2 Diabetic Patients With Foot Wounds, Compared to Diabetic Patients Without Foot Wounds

Conditions:   Type 2 Diabetes;   Foot Wound
Intervention:   Other: questionnaire
Sponsor:   Centre Hospitalier Universitaire Dijon
Not yet recruiting

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Linagliptin;   Drug: Empagliflozin;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Recruiting

Insulin Fiasp vs. Insulin Novorapid During Pregnancy and Laction in Women With Pre-existing Diabetes

Conditions:   Diabetes Mellitus;   Pregnancy Complications
Interventions:   Drug: Faster-acting Aspart insulin Fiasp;   Drug: Control (insulin Novorapid)
Sponsor:   Rigshospitalet, Denmark
Not yet recruiting

Effects of Diabetes Medications on Adrenal Function and Intestinal Microbiota

Condition:   Type 2 Diabetes
Interventions:   Drug: GLP-1 receptor agonist;   Drug: SGLT2 inhibitor
Sponsor:   University of Tartu
Recruiting

Empaglifozin in Early Diabetic Kidney Disease

Conditions:   Diabetic Kidney Disease;   Diabetes Mellitus Type 2
Interventions:   Drug: Empagliflozin;   Other: Placebo
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting

Safety and Efficacy of Dapagliflozin in Asian T2DM Subjects With Inadequate Glycemic Control on Metformin/Saxagliptin

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Dapagliflozin 10 mg;   Drug: Dapagliflozin 5 mg;   Drug: Dapagliflozin 10 mg placebo to match;   Drug: Dapagliflozin 5 mg placebo to match;   Drug: Saxagliptin 5 mg;   Drug: Metformin
Sponsor:   AstraZeneca
Recruiting

Using Peer Mentors to Support PACT Team Efforts to Improve Diabetes Control

Condition:   Type 2 Diabetes Mellitus
Intervention:   Behavioral: Peer Mentoring
Sponsor:   VA Office of Research and Development
Completed

Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals

Conditions:   Diabetes Mellitus Type 1;   Diabetes Mellitus Type 2
Intervention:   Drug: Sitagliptin (Januvia)
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Mapping Genes for Type 2 (Non-Insulin Dependent) Diabetes Mellitus

Conditions:   Genetic Variation;   Diabetes
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

Conditions:   Diabetes;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Enrolling by invitation

Genetics of Diabetes Audit and Research in Tayside Scotland (DOLORisk Dundee)

Condition:   Diabetic Neuropathic Pain
Intervention:   Genetic: Identification of genetic causes of diabetic neuropathic pain
Sponsors:   University of Dundee;   Wellcome Trust;   Diabetes UK
Active, not recruiting

A Study Comparing the Injection Site Pain Experience After the Injection of Semaglutide B and Semaglutide D With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and Obesity

Conditions:   Healthy Volunteers Diabetes Mellitus, Type 2;   Healthy Volunteers Overweight;   Healthy Volunteers Obesity
Interventions:   Drug: Semaglutide (administered by DV3396 pen);   Drug: Semaglutide (administered by PDS290 pen)
Sponsor:   Novo Nordisk A/S
Recruiting

Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes Mellitus

Conditions:   Obesity;   Bariatric Surgery;   Morbid Obesity;   Diabetes Mellitus Type 2;   Diet Therapy
Interventions:   Other: Roux-en-Y Gastric Bypass;   Other: Caloric Restriction
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Evaluation of Corneal Confocal Microscopy for the Identification and Prediction of Neuropathy in Type 1 Diabetes

Conditions:   Diabetic Polyneuropathy;   Diabetes Mellitus;   Diabetes Mellitus, Type 1;   Diabetes Mellitus, Type 2;   Diabetes Complications
Intervention:   Other: Exposure: Corneal nerve fibre morphology by the CCM Procedure
Sponsors:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of Calgary;   Queensland University of Technology;   University of Michigan;   University of Manchester
Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of KQ-791 in Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: KQ-791;   Drug: Placebo
Sponsor:   Kaneq Bioscience Limited
Completed

Inpatient Diabetes Mellitus (DM) Management With Continuous Glucose Monitoring Devices, a Pilot Study.

Condition:   Diabetes Mellitus
Interventions:   Device: Continuous glucose Monitoring (CGM) device and Point of Care (POC) blood glucose;   Other: Point of Care (POC) blood glucose
Sponsors:   University of Maryland, Baltimore;   DexCom, Inc.
Recruiting

PREMIER: PREvention of Metabolic Illness Through prEcision nutRition

Conditions:   Obesity;   Type 2 Diabetes;   Metabolic Syndrome;   Diet Habit;   Nutritional and Metabolic Disease;   Food Preferences
Intervention:   Other: Dietary intervention
Sponsors:   Massachusetts General Hospital;   NORCH (Nutrition Obesity Research Center at Harvard);   Boston Area Diabetes Endocrinology Research Center
Not yet recruiting

Control:Diabetes Pilot Study I

Conditions:   Insulin Treated Type 2 Diabetes Mellitus;   Diabetes Mellitus, Type 1
Intervention:   Other: Control:Diabetes mobile app
Sponsor:   Brigham and Women's Hospital
Recruiting

Mood and Insulin Resistance in Adolescents At-Risk for Diabetes

Conditions:   Depression;   Impaired Glucose Tolerance
Interventions:   Other: The Blues Program;   Other: Hey Durham
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Institutes of Health Clinical Center (CC)
Completed

Phase 2b Study in NASH to Assess IVA337

Condition:   Non-Alcoholic Steatohepatitis (NASH)
Interventions:   Drug: IVA337;   Drug: Placebo
Sponsor:   Inventiva Pharma
Active, not recruiting

Cooking Matters for Diabetes - A 6-Week Program for Practical Application of Diabetes Self-Management Education

Conditions:   Diabetes Mellitus;   Type 1 Diabetes;   Type 2 Diabetes
Interventions:   Behavioral: Cooking Matters for Diabetes;   Other: Usual Diabetes Care
Sponsors:   Ohio State University;   Academy of Nutrition and Dietetics
Recruiting

Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids

Conditions:   Type II Diabetes Mellitus;   Gestational Diabetes Mellitus
Interventions:   Other: Rotating fluids protocol;   Other: Insulin infusion protocol
Sponsor:   Geisinger Clinic
Recruiting

Dapagliflozin Patient Satisfaction Survey

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsors:   AstraZeneca;   Optum, Inc.
Completed

Insulin Start Therapy Application With Resources and Training

Condition:   Diabetes Mellitus, Type 2
Interventions:   Behavioral: I-START;   Behavioral: Standard Insulin Administration Education
Sponsor:   University of Pittsburgh
Not yet recruiting

Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers

Condition:   Healthy Volunteers
Interventions:   Drug: Placebo;   Drug: Canagliflozin
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Molecular and Clinical Profile of Diabetes Mellitus and Its Complications

Conditions:   Diabetes Mellitus, Type 2;   Diabetic Nephropathy;   Obesity
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Suspended

A Randomized Trial to Slow the Progression of Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Behavioral: Diabetes Management Package (DMP);   Behavioral: M-POWER Rewards
Sponsors:   Duke-NUS Graduate Medical School;   National Medical Research Council (NMRC), Singapore;   SingHealth Polyclinics;   Singapore General Hospital;   Changi General Hospital
Recruiting

Effect of Fermentable Carbohydrate on Glucose Homeostasis

Condition:   Prediabetes
Interventions:   Dietary Supplement: Inulin;   Dietary Supplement: Cellulose
Sponsor:   Imperial College London
Completed

Food and Education Effects on Diabetes Study

Condition:   Diabetes Mellitus, Type 2
Intervention:   Other: Medically-tailored meal delivery and medical nutrition therapy
Sponsors:   Johns Hopkins University;   Moveable Feast;   Priority Partners MCO;   Leonard & Helen R. Stulman Charitable Foundation;   France-Merrick Foundation
Not yet recruiting

Effect of EGCG on the Body's Response to Insulin

Conditions:   Hypertension;   Obesity;   Type 2 Diabetes;   Insulin Resistance
Intervention:   Drug: EGCG
Sponsor:   University of Maryland, Baltimore
Withdrawn

The SIMBA Project - The Effect of a Prebiotic Supplement on Glucose Metabolism and Gut Microbiota in Obese Adults

Conditions:   Glucose Metabolism;   Metabolic Syndrome;   Gut Microbiota
Interventions:   Dietary Supplement: Fermented canola-seaweed;   Other: Placebo
Sponsors:   University of Copenhagen;   FermBiotics ApS
Recruiting

The Effects of Topical Corticosteroid Use on Insulin Sensitivity and Bone Turnover

Conditions:   Atopic Dermatitis;   Atopic Eczema
Interventions:   Drug: Betnovate, betamethasone dipropionate ointment 0.1% and placebo;   Drug: Protopic, tacrolimus ointment 0.1%
Sponsors:   Jacob Thyssen;   LEO Pharma
Recruiting

A Community-based Weight Loss Programme for Chinese Overweight Adults With Pre-diabetes

Condition:   Pre-diabetes
Interventions:   Behavioral: group-based lifestyle intervention;   Behavioral: Minimal intervention (SMS intervention)
Sponsor:   The University of Hong Kong
Active, not recruiting

A French Study to Evaluate the Usefulness of Implantable Continuous Glucose Monitoring (CGM) Sensor to Improve Glycemic Control in Participants With Diabetes Mellitus.

Condition:   Diabetes Mellitus
Interventions:   Device: Eversense XL;   Device: Usual SMBG or FGM device used by participants
Sponsors:   Hoffmann-La Roche;   Roche Diabetes Care France SAS
Active, not recruiting

A Phase 3/4 Clinical Study to Evaluate the Efficacy and Safety of Aramchol Versus Placebo in Subjects With NASH (ARMOR)

Condition:   Nonalcoholic Steatohepatitis (NASH)
Interventions:   Drug: Aramchol;   Drug: Placebo
Sponsor:   Galmed Research and Development, Ltd.
Recruiting

A Study of LY900020 in Healthy Chinese Participants

Condition:   Healthy
Interventions:   Drug: LY900020;   Drug: Metformin XR;   Drug: Atorvastatin;   Drug: Valsartan
Sponsor:   Eli Lilly and Company
Not yet recruiting

Tolerability and Risk of Adverse Events With a Probiotic Supplement

Condition:   Healthy Individuals
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: High dose F. prausnitzii and D. piger;   Dietary Supplement: Low dose F. prausnitzii and D. piger
Sponsors:   Sahlgrenska University Hospital, Sweden;   Metabogen AB
Completed

Mycoprotein Consumption and Glucose Absorption

Condition:   Healthy
Intervention:   Dietary Supplement: Mycoprotein Ingestion
Sponsors:   University of Exeter;   Quorn Foods
Completed

Effect of Breathing Maneuvers on Peripheral Glucose Metabolism

Conditions:   Vagus Nerve Stimulation;   Insulin Sensitivity;   Deep Breathing Maneuver
Intervention:   Other: deep breathing
Sponsor:   University Hospital Tuebingen
Not yet recruiting

Effect of Exercise Intervention on Body Composition and Quality of Life in Post-bariatric Surgery Patients

Condition:   Exercise Training
Intervention:   Other: walking exercise
Sponsor:   Chang Gung Memorial Hospital
Not yet recruiting

Internet Treatment for Persons With Overweight or Obesity

Condition:   Overweight and Obesity
Intervention:   Behavioral: Internet treatment for overweight and obese patients
Sponsor:   Region Örebro County
Not yet recruiting

Training in the Fasted State, Glucose Metabolism and Energy Balance

Condition:   Glucose Metabolism Disorders
Interventions:   Behavioral: Exercise;   Behavioral: Breakfast;   Behavioral: Maintain habitual habits
Sponsor:   University of Bath
Completed

Arterial Composition and Cardiovascular Outcome in DIabeteS

Conditions:   Diabetes Mellitus, Type 2;   Artery Disease;   Protein Deposition
Intervention:   Diagnostic Test: Proteome analysis
Sponsors:   University of Southern Denmark;   Odense University Hospital;   Steno Diabetes Center Odense
Active, not recruiting

Effect of Empagliflozin Versus Placebo on Brain Insulin Sensitivity in Patients With Prediabetes

Conditions:   PreDiabetes;   Body Weight
Interventions:   Drug: Empagliflozin 25mg;   Drug: Placebo Oral Tablet
Sponsor:   University Hospital Tuebingen
Active, not recruiting

Salsalate for Insulin Resistance in Schizophrenia

Conditions:   Schizophrenia;   Insulin Resistance
Intervention:   Drug: salsalate
Sponsors:   University of Maryland, Baltimore;   US Department of Veterans Affairs
Completed

Effects of Fenofibrate Therapy in Diabetic Nephropathy

Conditions:   Diabetes Mellitus;   Diabetic Nephropathies
Intervention:   Drug: Fenofibrate
Sponsors:   Singapore General Hospital;   National Medical Research Council (NMRC), Singapore
Recruiting

Effectiveness of Diabetes Prevention Education Program on Diabetes Prevention Among Prediabetes Population in Nepal

Condition:   Prediabetic State
Interventions:   Behavioral: Diabetes Prevention Education Program;   Behavioral: Diabetes Prevention Education brochure
Sponsors:   Norwegian University of Science and Technology;   Kathmandu University School of Medical Sciences
Recruiting

Online WIC Nutrition Education to Promote Farmers' Market Fruit and Vegetable Purchases and Consumption

Conditions:   Cardiovascular Diseases;   Cancer;   Type 2 Diabetes;   Obesity
Interventions:   Behavioral: WIC Fresh Start Program;   Behavioral: Existing Online Health Education
Sponsors:   William Paterson University of New Jersey;   USDA Food and Nutrition Service
Completed

Omadacycline Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis

Conditions:   Diabetes;   Wound Infection;   Healthy Volunteers
Interventions:   Drug: Omadacycline;   Procedure: Microdialysis Catheter Insertion
Sponsors:   Hartford Hospital;   Paratek Pharmaceuticals Inc
Not yet recruiting

Penile Length Restoration in Men With Diabetes Mellitus, Type II

Conditions:   Diabetes Mellitus, Type 2;   Penile Diseases
Interventions:   Device: RestoreX PTT - 6 months;   Device: RestoreX PTT - 3 months
Sponsor:   Mayo Clinic
Recruiting

Brain Imaging in the Diabetes Prevention Program Outcomes Study

Condition:   Alzheimer Disease
Interventions:   Drug: 18F-MK-6240;   Drug: 11C-PIB
Sponsors:   José A. Luchsinger;   Albert Einstein College of Medicine;   George Washington University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enrolling by invitation

Mediterranean Diet Versus Exercise to Lower Cardiometabolic Risk

Conditions:   Overweight or Obesity;   Visceral Steatosis
Intervention:   Other: energy deficit
Sponsors:   Oslo University Hospital;   The National Association for Public Health, Norway
Not yet recruiting

The Effects of BAY1193397 on Skin Capillary Blood Flow and Transcutaneous Oxygen Pressure

Condition:   Diabetic Foot
Interventions:   Drug: BAY1193397;   Drug: Placebo
Sponsor:   Bayer
Completed

Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs

Condition:   Bipolar Disorder
Interventions:   Drug: Metformin;   Behavioral: healthy lifestyle intervention (LIFE)
Sponsors:   Melissa Delbello;   Patient-Centered Outcomes Research Institute
Recruiting

The Effect of Lactation on Insulin Sensitivity and Lipolysis in Women

Conditions:   GDM;   Lactation
Intervention:   Diagnostic Test: Hyperinsulinemic-euglycemic clamp
Sponsors:   Yale University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Not yet recruiting

Family Investigation of Nephropathy and Diabetes (F.I.N.D.)

Conditions:   Diabetic Nephropathy;   Diabetes Mellitus;   Diabetic Kidney Disease;   Albuminuria
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

A 5-year Longitudinal Observational Study of Patients With Nonalcoholic Fatty Liver (NAFL) or Nonalcoholic Steatohepatitis (NASH)

Conditions:   Nonalcoholic Fatty Liver;   Nonalcoholic Steatohepatitis
Intervention:  
Sponsor:   Target PharmaSolutions, Inc.
Recruiting

The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men

Conditions:   Human Immunodeficiency Virus;   Cardiometabolic Risk
Interventions:   Behavioral: HOLA Component 1;   Behavioral: HOLA Component 2;   Behavioral: HOLA Component 3;   Behavioral: HOLA Component 4
Sponsors:   University of Miami;   National Institute on Minority Health and Health Disparities (NIMHD)
Recruiting

Automated Structured Education Based on an App and AI in Chinese Patients With Type 1 Diabetes

Condition:   Type 1 Diabetes
Intervention:   Behavioral: Automated structured education intervention based on an app and artificial intelligence
Sponsor:   Second Xiangya Hospital of Central South University
Not yet recruiting

Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial

Condition:   Obesity
Intervention:   Device: VeSTAL
Sponsors:   Neurovalens Ltd.;   University of California, San Diego;   University of Ulster;   Exploristics;   Compliance Solutions
Recruiting