Peripheral Arterial Disease

Clinical Trial Finder

Many patients with peripheral arterial disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Daily Step-based Exercise Using Fitness Monitors for Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Behavioral: Daily Step-based Exercise;   Behavioral: Symptom-based Exercise;   Device: Fitbit Fitness Monitor
Sponsors:   University of North Carolina, Chapel Hill;   North Carolina Translational and Clinical Sciences Institute
Recruiting - verified March 2017

The Effects of BAY1193397 on Skin Capillary Blood Flow and Transcutaneous Oxygen Pressure

Condition:   Diabetic Foot
Interventions:   Drug: BAY1193397;   Drug: BAY1193397;   Drug: Placebo
Sponsor:   Bayer
Not yet recruiting - verified April 2017

Soundbite Crossing System Peripheral First in Man (SCSPFIM)

Condition:   Peripheral Artery Disease
Intervention:   Device: CTO Crossing
Sponsor:   SoundBite Medical Solutions, Inc.
Recruiting - verified February 2017

Revolution™ Peripheral Atherectomy System for Lower Extremity Peripheral Arterial Revascularization

Condition:   Peripheral Artery Disease
Intervention:   Device: REVEAL
Sponsors:   Rex Medical;   Syntactx
Not yet recruiting - verified April 2017

Safety and Feasibility of the Shockwave Lithoplasty® System for the Treatment of Peripheral Vascular Stenosis

Condition:   Peripheral Arterial Disease
Intervention:   Device: Shockwave Lithoplasty® System
Sponsor:   Shockwave Medical, Inc.
Recruiting - verified April 2017

Use of Entresto Sacubitril/Valsartan for the Treatment of Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Drug: Entresto;   Drug: Placebo group
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   American Heart Association
Recruiting - verified April 2017

Advancing Personalized Antidepressant Treatment Using PET/MRI

Condition:   Depression
Interventions:   Drug: Escitalopram;   Drug: Placebo
Sponsor:   Stony Brook University
Recruiting - verified April 2017

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified April 2017

Role of PPAR-y Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)

Condition:   Systemic Lupus Erthematosus
Interventions:   Radiation: PET/CT;   Drug: Pioglitazone;   Procedure: Vascular function studies
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified November 21, 2016

Role of a Novel Exercise Program to Prevent Post-thrombotic Syndrome

Condition:   Acute Deep Vein Thrombosis
Interventions:   Other: Exercise;   Other: Control
Sponsors:   VA Office of Research and Development;   University of Maryland
Recruiting - verified April 2017

Effects of Anesthetics on Postoperative Cognitive Function of Patients Undergoing Endovascular Repair of Aortic Aneurysm and Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities.

Conditions:   Endovascular Repair of Aortic Aneurysm;   Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities
Interventions:   Drug: Sevoflurane;   Drug: Propofol;   Drug: Remifentanil
Sponsor:   Tao Zhang
Recruiting - verified April 2017

Collaborative-care Rehabilitation After Dysvascular Amputation

Conditions:   Diabetes Complications;   Peripheral Arterial Disease
Interventions:   Behavioral: Exercise;   Behavioral: Walking Program;   Behavioral: Health Self-Management Support
Sponsor:   University of Colorado, Denver
Recruiting - verified April 2017

Safety Trial Of CTX Cells In Patients With Lower Limb Ischaemia

Condition:   Peripheral Arterial Disease
Intervention:   Biological: CTX DP
Sponsor:   ReNeuron Limited
Active, not recruiting - verified April 2017

Venous Vascularization and Inflammation on Contrast-enhanced Ultrasound (CEUS) in Patients With Thrombosis

Condition:   Thrombosis
Intervention:   Other: No intervention
Sponsor:   University Hospital, Basel, Switzerland
Terminated - verified April 2017

Exercise and Cardiovascular Control During Upright Tilt in Older Adults With Type 2 Diabetes

Conditions:   Cardiovascular;   Diabetic
Interventions:   Behavioral: Aerobic Exercise and Strength Exercise;   Behavioral: Strength training
Sponsors:   University of British Columbia;   Canadian Institutes of Health Research (CIHR)
Completed - verified April 2017

Cardiopulmonary Function Assessment and NO-Based Therapies for Patients With Hemolysis-Associated Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Interventions:   Drug: Nitric Oxide/INP Pulse Delivery;   Drug: Nitric Oxide/INO Pulse Delivery
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified December 7, 2015

Endothelial Cell Dysfunction in Pulmonary Hypertension

Condition:   Hypertension, Pulmonary
Interventions:   Procedure: Heart Catheterization;   Drug: Nitric Oxide;   Drug: Nitric Oxide/INO Pulse Delivery;   Drug: Sodium Nitrite
Sponsor:   National Institutes of Health Clinical Center (CC)
Completed - verified December 7, 2016

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Peripheral Artery Disease
Intervention:   Procedure: MRI
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified February 17, 2017

Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension

Conditions:   Sickle Cell Anemia;   Pulmonary Hypertension
Interventions:   Drug: Nitric Oxide;   Device: INO Pulse - NO Delivery System
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   Mallinckrodt
Completed - verified November 9, 2015

Evaluation of Patients With Heart Disease Not Eligible for Research Protocols

Condition:   Heart Disease
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified March 22, 2017