Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Ubiquinol in Parkinson's Disease: Safety, Tolerability, and Effects Upon Oxidative Damage and Mitochondrial Biomarkers

Condition:   Parkinson Disease
Interventions:   Drug: Ubiquinol;   Dietary Supplement: Placebo
Sponsor:   Weill Medical College of Cornell University
Completed - verified February 2017

Molecular-Functional Imaging of Hypoxia in Childhood Sarcomas

Conditions:   Rhabdomyosarcoma;   Non-Rhabdo. Soft Tissue Sarcoma
Interventions:   Drug: 18F-FAZA (F18-Fluoroazomycin Arabinoside);   Diagnostic Test: Blood Oxygen Level Dependent [BOLD] MRI;   Diagnostic Test: Diffusion-Weighted [DW] MRI;   Diagnostic Test: Magnetic Resonance Spectroscopy [MRS]
Sponsor:   The Hospital for Sick Children
Enrolling by invitation - verified February 2017

Intense Pulsed Light as an Adjunctive to Bromonidine for the Treatment of Rosacea

Condition:   Rosacea
Interventions:   Drug: Bromonide 0.33% gel;   Device: Intense Pulsed Light (M22)
Sponsor:   Rabin Medical Center
Not yet recruiting - verified January 2017

The Effect of High Dose Methylprednisolone on Nailfold in Early Systemic Sclerosis ( SSc )

Conditions:   Systemic Sclerosis;   Raynaud Phenomena
Interventions:   Drug: Methylprednisolone;   Other: sodium chloride
Sponsor:   Radboud University
Enrolling by invitation - verified January 2017

Bedside Versus Operating Room Burr-Hole Drainage of Chronic Subdural Hematoma (DECIDE)

Condition:   Chronic Subdural Hematoma
Interventions:   Procedure: CSDH - Bedside twist drill technique;   Procedure: CSDH - Operating Room Burr-hole technique
Sponsor:   Hamilton Health Sciences Corporation
Not yet recruiting - verified February 2017

Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke

Conditions:   Stroke;   Stroke, Acute;   Brain Injury, Acute
Interventions:   Biological: Umbilical Cord Blood;   Other: Placebo
Sponsors:   Joanne Kurtzberg, MD;   The Marcus Foundation;   Emory University;   M.D. Anderson Cancer Center
Recruiting - verified February 2017

Safety and Efficacy of Alteplase When Administered in Chinese Patients With Acute Ischemic Hemispheric Stroke Where Thrombolysis is Initiated Between 3 and 4.5 Hours After Stroke Onset

Condition:   Stroke
Intervention:   Drug: alteplase
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic Sclerosis

Condition:   Systemic Sclerosis
Interventions:   Drug: SAR156597 (ACT14604);   Drug: Placebo
Sponsor:   Sanofi
Recruiting - verified February 2017

Efficacy and Safety Study of CNTO 2476 in Participants With Visual Acuity Impairment Associated With Geographic Atrophy (GA) Secondary to Age Related Macular Degeneration (AMD)

Conditions:   Visual Acuity;   Geographic Atrophy;   Macular Degeneration
Interventions:   Drug: CNTO 2476 (6.0 x 10^4 cells);   Drug: CNTO 2476 (3.0 x 10^5 cells)
Sponsor:   Janssen Pharmaceutical K.K.
Not yet recruiting - verified February 2017

Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist

Condition:   Intracerebral Hemorrhage
Interventions:   Drug: Tranexamic acid;   Drug: Saline 0.9%
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation
Recruiting - verified February 2017

Augmenting Cognitive Training In Older Adults

Condition:   Aging
Interventions:   Behavioral: Cognitive Training;   Device: tDCS (active stimulation);   Device: tDCS (sham stimulation);   Behavioral: Educational Training
Sponsors:   University of Florida;   University of Miami;   University of Arizona
Recruiting - verified February 2017

Incidence of Significant Mitral Regurgitation in Acute Heart Failure Patients

Conditions:   Acute Heart Failure;   Mitral Regurgitation
Intervention:   Procedure: Transthoracic Echocardiogram (TTE) Assesment
Sponsors:   Metanoic Health Ltd.;   Abbott Vascular
Recruiting - verified February 2017

Basilar Artery Occlusion Chinese Endovascular Trial

Conditions:   Basilar Artery Occlusion;   Ischemic Stroke;   Cerebrovascular Disorders
Interventions:   Procedure: Mechanical embolectomy;   Drug: Medical Treatment
Sponsors:   Xuanwu Hospital, Beijing;   Zhangzhou Municipal Hospital of Fujian Province;   The First People's Hospital of Changzhou;   Xinqiao Hospital of Chongqing;   Changhai Hospital;   Baotou Central Hospital;   The 101st Hospital of Chinese People's Liberation Army;   Linyi People's Hospital;   Zhongshan People's Hospital, Guangdong, China;   PLA 264 Hospital, Taiyuan, Shanxi;   Nanjing First People's Hospital;   Tianjin TEDA Hospital;   The First Affiliated Hospital with Nanjing Medical University;   Liaocheng Third People's Hospital;   Luoyang Central Hospital;   Subei People's Hospital of Jiangsu Province;   PLA 148 Hospital, Zibo, Shandong;   Hebei General Hospital;   Shengli Oilfield Hospital;   The 306 Hospital of People's Liberation Army;   Shenzhen Bao'an District People's Hospital;   First Hospital of Jilin University;   Henan Provincial Hospital;   Peking University Binhai Hospital;   Beijing Tiantan Hospital;   The Military General Hospital of Beijing, PLA;   The First Affiliated Hospital of Shanxi Medical University;   The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine;   Beijing Luhe Hospital;   Nantong University;   The Affiliated Hospital Of Guizhou Medical University;   Nanning Second People's Hospital;   Chongqing Three Gorges Central Hospital
Recruiting - verified June 2016

Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension

Conditions:   Scleroderma, Diffuse;   Scleroderma, Systemic;   Scleroderma, Limited;   Sclerosis, Progressive Systemic;   Skin Diseases;   Connective Tissue Diseases;   Pathologic Processes;   Autoimmune Diseases
Interventions:   Drug: Oral Ifetroban;   Drug: Oral Placebo
Sponsor:   Cumberland Pharmaceuticals
Recruiting - verified February 2017

INVEST: Minimally Invasive Endoscopic Surgery vs. Medical Management in Supratentorial Intraparenchymal Hemorrhage

Condition:   Intracranial Hemorrhage
Interventions:   Device: Apollo MIES;   Other: Medical Management
Sponsor:   J. Mocco
Recruiting - verified February 2017

INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo in Patients With Brain Hemorrhage

Condition:   Intracranial Hemorrhage
Intervention:   Device: Apollo MIES
Sponsor:   J. Mocco
Recruiting - verified February 2017

(MitraClip in Non-Responders to Cardiac Resynchronization Therapy)

Condition:   MITRAL REGURGITATION
Intervention:   Device: MITRACLIP
Sponsors:   Hospital Clinic of Barcelona;   Abbott
Recruiting - verified February 2017

A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis

Condition:   Scleroderma, Systemic
Interventions:   Drug: Nintedanib;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

ERic Acute StrokE Recanalization (ERASER)

Condition:   Ischemic Stroke
Intervention:   Device: ERIC® and SOFIA™
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Recruiting - verified February 2017

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion
Recruiting - verified February 2017

DLBS1033 for the Treatment of Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: Placebo;   Drug: DLBS1033
Sponsor:   Dexa Medica Group
Terminated - verified February 2017

A CBT-based Internet Intervention for Adults With Tinnitus in the United Kingdom

Condition:   Tinnitus
Intervention:   Behavioral: CBT-based internet-intervention for tinnitus
Sponsors:   Anglia Ruskin University;   Linkoeping University
Active, not recruiting - verified February 2017

Treatment of Heart Failure and Associated Functional Mitral Valve Regurgitation

Condition:   Mitral Valve Regurgitation
Intervention:   Device: ARTO System
Sponsor:   Mvrx, Inc.
Recruiting - verified February 2017

Clinical Biomarkers in Alpha-mannosidosis

Condition:   Alpha-Mannosidosis
Intervention:  
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 17, 2017

Comparison of Thrombectomy and Standard Care for Ischemic Stroke in Patients Ineligibility for Tissue Plasminogen Activator Treatment

Condition:   Ischemic Stroke
Interventions:   Device: Thrombectomy;   Other: Best medical care
Sponsors:   University Hospital Heidelberg;   University Hospital, Aachen;   Klinikum Augsburg;   Vivantes Krankenhaus Berlin Neukölln;   Ruhr University of Bochum;   Klinikum Dortmund Wirbelsäulenchirurgie;   University of Erlangen-Nürnberg Medical School;   Alfried Krupp Krankenhaus Essen;   University Hospital, Essen;   University Hospital Freiburg;   University Medical Center Goettingen;   Universitätsklinikum Hamburg-Eppendorf;   Universitätsklinik für Neuroradiologie Innsbruck;   Universitätsklinikum Köln;   The Wagner-Jauregg Provincial Neuropsychiatric Clinic;   Klinikum der Universitaet Muenchen;   Klinikum rechst der Isar Technische Universitaet Muenchen;   KLINIKUM VEST Recklinghausen;   Wuerzburg University Hospital;   Asklepios Kliniken Hamburg GmbH
Terminated - verified February 2017

A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke

Condition:   Stroke
Interventions:   Drug: Alteplase;   Drug: Alteplase Placebo;   Drug: Aspirin;   Drug: Aspirin Placebo
Sponsor:   Genentech, Inc.
Active, not recruiting - verified February 2017

PERIGON Pivotal Trial

Condition:   Aortic Stenosis
Intervention:   Device: Model 400 aortic valve bioprosthesis
Sponsors:   Medtronic Cardiovascular;   Medtronic
Recruiting - verified February 2017

Skeletal Muscle Biomarkers in People With Fragile Sarcolemmal Muscular Dystrophy

Condition:   Genetic Disorder
Intervention:  
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Neurological Disorders and Stroke (NINDS);   National Institutes of Health Clinical Center (CC);   University of Massachusetts, Worcester
Recruiting - verified December 15, 2016

Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI

Conditions:   Tricuspid Valve Regurgitation, Non-rheumatic;   Mitral Valve Regurgitation
Intervention:  
Sponsors:   Medical College of Wisconsin;   Children's Hospital and Health System Foundation, Wisconsin
Active, not recruiting - verified February 2017

Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis

Condition:   Sinus Thrombosis, Intracranial
Interventions:   Drug: Endovascular thrombolysis;   Drug: Heparin
Sponsors:   Jan Stam, MD, PhD;   Dutch Heart Foundation
Terminated - verified November 2016

Brain Imaging Study in Menopausal Women With and Without Major Depressive Disorder

Conditions:   Menopause;   Depression
Interventions:   Drug: MDD diagnosis and Estrogen treatment;   Drug: MDD diagnosis and Fluoxetine treatment;   Drug: MDD diagnosis with both Estrogen and Fluoxetine treatment;   Drug: No depression and estrogen treatment
Sponsor:   University of Pennsylvania
Completed - verified February 2017

Multimodal Resonance Imaging for Outcome Prediction on Coma Patients

Condition:   Coma
Intervention:   Procedure: Multimodal MRI
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed - verified December 2008