Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)

Condition:   Sclerosis, Systemic
Interventions:   Drug: Placebo;   Drug: Tocilizumab
Sponsor:   Hoffmann-La Roche
Not yet recruiting - verified May 2015

The Safety and Efficacy Study of High Dose Atorvastatin After Thrombolytic Treatment in Acute Ischemic Stroke

Condition:   Stroke
Intervention:   Device: atorvastatin
Sponsors:   Second Affiliated Hospital, School of Medicine, Zhejiang University;   First Hospital of Jilin University
Recruiting - verified May 2015

Helping Stroke Patients With ThermoSuit Cooling

Conditions:   Stroke;   Brain Ischemia
Interventions:   Device: ThermoSuit Cooling Induction;   Drug: Magnesium Sulfate;   Drug: tPA;   Drug: Propofol;   Drug: Etomidate
Sponsors:   Life Recovery Systems;   Tulane University School of Medicine;   CHRISTUS Health
Not yet recruiting - verified May 2015

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion Pharmaceuticals, Inc.
Not yet recruiting - verified May 2015

The Effect of the Hole in the Cardiac Septum Developed by the MitraClip Procedure on the Blood Flow Mechanics

Condition:   Atrial Septal Defect
Interventions:   Other: 2D-/3D-TTE;   Other: 3D-TEE;   Other: Walking Test;   Procedure: MitraClip procedure
Sponsor:   RWTH Aachen University
Not yet recruiting - verified May 2015

A Comparative Phase 2 Study Assessing the Efficacy of Triheptanoin, an Anaplerotic Therapy in Huntington's Disease

Condition:   Huntington Disease
Interventions:   Drug: Triheptanoin oil;   Drug: Placebo
Sponsors:   Institut National de la Santé Et de la Recherche Médicale, France;   Ultragenyx Pharmaceutical Inc
Not yet recruiting - verified April 2015

Quality of Life After Stroke Using a Telemedicine-based Stroke Network

Condition:   Stroke
Intervention:   Drug: Alteplase
Sponsors:   Thomas Jefferson University;   Genentech, Inc.
Recruiting - verified May 2015

Effects of Home-based Mirror Therapy Combined With Task-oriented Training for Patients With Stroke

Condition:   Stroke
Interventions:   Behavioral: home-based therapy;   Behavioral: hospital-based therapy
Sponsor:   Chang Gung Memorial Hospital
Not yet recruiting - verified April 2015

Treatment of Refractory Auditory Verbal Hallucinations With tDCS in Schizophrenia

Condition:   Schizophrenia
Intervention:   Device: tDCS
Sponsor:   Seoul National University Hospital
Not yet recruiting - verified April 2015

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

Conditions:   Diffuse Intrinsic Pontine Glioma;   Malignant Glioma;   Recurrent Childhood Brain Neoplasm
Interventions:   Procedure: Diffusion Tensor Imaging;   Procedure: Diffusion Weighted Imaging;   Procedure: Dynamic Contrast-Enhanced Magnetic Resonance Imaging;   Procedure: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging;   Other: Laboratory Biomarker Analysis;   Procedure: Magnetic Resonance Spectroscopic Imaging;   Biological: Pembrolizumab;   Procedure: Perfusion Magnetic Resonance Imaging
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified February 2015

Deferoxamine and Xingnaojing Injection Treatment in Intracerebral Hemorrhage

Condition:   Intracerebral Hemorrhage
Interventions:   Drug: deferoxamine;   Drug: Xingnaojing injection;   Drug: Normal saline
Sponsors:   Capital Medical University;   Beijing Tiantan Hospital;   Peking University First Hospital;   People’s Hospital of Beijing Daxing District;   Beijing Haidian Hospital;   The 263 Hospital of PLA ;   Beijing Aerospace General Hospital;   Peking University Third Hospital;   Beijing Pinggu District Hospital;   Beijing Shunyi District hospital;   General Hospital of Beijing PLA Military Region;   Beijing Luhe Hospital;   Beijing Fangshan District Liangxiang Hospital;   Beijing Neurosurgical Institute;   Beijing Jishuitan Hospital;   Beijing Ditan Hospital;   Beijing Youyi Hospital;   XIyuan Hospital CACMS;   Peking University People's Hospital;   The Second Artillery General Hospital;   Chinese PLA General Hospital
Recruiting - verified May 2015

Physiological Effects of Nutritional Support in Patients With Parkinson's Disease

Conditions:   Parkinson Disease;   Idiopathic Parkinson Disease
Interventions:   Dietary Supplement: Baicalin, Curcumin, Ganoderma, Omega 3;   Dietary Supplement: Intravenous and Oral n—acetyl cysteine
Sponsor:   Thomas Jefferson University
Recruiting - verified May 2015

CARILLON Mitral Contour System® for Reducing Functional Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Heart Failure
Intervention:   Device: CARILLON Mitral Contour System
Sponsor:   Cardiac Dimensions Pty Ltd
Recruiting - verified May 2015

The Pleth Variability Index and Hypotension at Caesarean Under Spinal.

Condition:   Caesarean Section
Intervention:  
Sponsor:   Sheffield Teaching Hospitals NHS Foundation Trust
Completed - verified May 2015

Open-Label Creatine Study for Female Meth Users

Conditions:   Depression;   Dual Diagnosis;   Substance Use
Intervention:   Drug: Creatine monohydrate
Sponsor:   Perry Renshaw
Terminated - verified May 2015

Trevo and Medical Management Versus Medical Management Alone in Wake Up and Late Presenting Strokes

Condition:   Ischemic Stroke
Interventions:   Device: Trevo Thrombectomy Procedure;   Other: Medical Management
Sponsor:   Stryker Neurovascular
Recruiting - verified May 2015

High-field Brain Magnetic Resonance Spectroscopy

Condition:   Healthy
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Active, not recruiting - verified May 2015

Effect of Natalizumab on Infarct Volume in Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: natalizumab;   Drug: Placebo
Sponsor:   Biogen Idec
Completed - verified April 2015

DELTA Trial: Does Embolization With Larger Coils Lead to Better Treatment of Aneurysms Trial

Condition:   Cerebral Aneurysm
Intervention:   Device: Endovascular coiling with standard 10-caliber platinum coils or 15-caliber platinum coils
Sponsors:   Centre hospitalier de l'Université de Montréal (CHUM);   DePuy Synthes - Codman Neuro;   Johnson & Johnson Medical Companies
Recruiting - verified May 2015

Blood Pressure Variability in Acute Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:  
Sponsors:   Aristotle University Of Thessaloniki;   A & D Company Limited 
Recruiting - verified May 2015

Observational Study of Ischaemic Stroke

Conditions:   Stroke;   Motor Activity
Intervention:  
Sponsor:   ReNeuron Limited
Recruiting - verified May 2015

Study of the Capacity of the MRI Spectroscopy to Define the Tumor Area Enriched in Glioblastoma Stem Cells. Proof of Concept Study

Condition:   Glioblastoma
Intervention:   Procedure: Surgery (based on preoperative multimodal MRI) followed by the standard radio-chemotherapy stupp protocol
Sponsor:   Institut Claudius Regaud
Recruiting - verified March 2015

Improving Cancer Foci Detection in Prostate Cancer Using Multiparametric MRI/MRS

Condition:   Prostate Cancer
Intervention:  
Sponsor:   University of Maryland
Active, not recruiting - verified May 2015

Early and Longitudinal Assessment of Neurodegeneration in the Brain and Spinal Cord in Friedreich's Ataxia

Condition:   Friedreich Ataxia
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Bob Allison Ataxia Research Center;   Friedreich's Ataxia Research Alliance
Recruiting - verified May 2015

Effects of the Quantity of Repetitive Transcranial Magnetic Stimulation(rTMS) on the Recovery After Stroke

Conditions:   Stroke;   Hemiplegia
Intervention:   Device: repetitive transcranial magnetic stimulation (rTMS)
Sponsors:   Seoul National University Bundang Hospital;   Asan Medical Center;   Gyeongsang National University Hospital;   Hanyang University;   Seoul National University Boramae Hospital
Terminated - verified May 2015

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