Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Multicenter, Randomized, Controlled Study to Assess Mitral vAlve reconsTrucTion for advancEd Insufficiency of Functional or iscHemic ORigiN

Condition:   Mitral Valve Insufficiency
Interventions:   Device: MitraClip system (Abbott Vascular, Menlo Park, USA);   Procedure: Reconstructive mitral valve surgery
Sponsors:   Universitätsklinikum Köln ;   Clinical Trials Center Cologne
Not yet recruiting - verified February 2015

Ablation of the Pulmonary Artery With High Pulmonary Hypertension During Mitral Valve Surgery

Condition:   Pulmonary Hypertension
Interventions:   Procedure: Surgical ablation of ganglion plexus pulmonary artery.;   Procedure: mitral valve surgery
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified February 2015

Deferoxamine and Xingnaojing Injection Treatment in Intracerebral Hemorrhage

Condition:   Intracerebral Hemorrhage
Interventions:   Drug: deferoxamine;   Drug: Xingnaojing injection;   Drug: Normal saline
Sponsors:   Capital Medical University;   Beijing Tiantan Hospital;   Peking University First Hospital;   People’s Hospital of Beijing Daxing District;   Beijing Army General Hospital;   Beijing Haidian Hospital;   The 263 Hospital of People Liberation Army;   Beijing Aerospace General Hospital;   Peking University Third Hospital;   Beijing Pinggu District Hospital;   Beijing Shunyi District hospital;   General Hospital of Beijing PLA Military Region;   Beijing Luhe Hospital;   Beijing Fangshan District Liangxiang Hospital;   Beijing Neurosurgical Institute;   Beijing Jishuitan Hospital;   Beijing Ditan Hospital;   Beijing Youyi Hospital;   XIyuan Hospital CACMS;   Peking University People's Hospital;   The Second Artillery General Hospital
Not yet recruiting - verified February 2015

BestFIT: a Personalized Weight Loss Program

Condition:   Obesity
Interventions:   Behavioral: Behavioral weight loss therapy;   Behavioral: Meal replacements;   Behavioral: Enhanced behavioral weight loss therapy
Sponsors:   HealthPartners Institute for Education and Research;   Drexel University;   University of Michigan;   University of Minnesota - Clinical and Translational Science Institute;   University of Washington
Not yet recruiting - verified February 2015

Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot Study

Conditions:   Coronary Artery Disease;   Mitral Valve Insufficiency;   Aortic Valve Stenosis;   Aortic Valve Regurgitation;   Mitral Valve Stenosis;   Coronary Artery Bypass Graft Triple Vessel
Intervention:   Procedure: Ambulation orderly
Sponsors:   Baystate Medical Center;   Springfield College
Not yet recruiting - verified February 2015

Sleep Breathing Disorders, a Main Trigger for Cardiac ARythmias in Type I Myotonic Dystrophy ?

Condition:   Myotonic Dystrophy
Intervention:  
Sponsor:   University Hospital, Grenoble
Recruiting - verified February 2015

Stress Echocardiography Versus Exercise ECG in Women With Chest Pain

Condition:   Coronary Artery Disease
Interventions:   Procedure: Exercise ECG;   Procedure: Stress Echocardiography
Sponsor:   London North West Healthcare NHS Trust
Recruiting - verified February 2015

Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis

Condition:   Scleroderma, Systemic
Interventions:   Drug: Riociguat (Adempas, BAY63-2521);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified February 2015

Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Organic MR

Conditions:   Heart Valve Diseases;   Mitral Valve Insufficiency;   Heart; Dysfunction Postoperative, Cardiac Surgery;   Heart; Disease, Mitral(Valve);   Diseases of Mitral Valve
Intervention:  
Sponsor:   UMC Utrecht
Recruiting - verified February 2015

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)

Condition:   Brain Ischemia
Interventions:   Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
Sponsor:   Genentech, Inc.
Recruiting - verified February 2015

PERIGON Pivotal Trial

Condition:   Aortic Valve Replacement
Intervention:   Device: Model 400 aortic valve bioprosthesis
Sponsors:   Medtronic Cardiovascular;   Medtronic
Recruiting - verified February 2015

Trevo® Retriever Registry Post Market Surveillance

Condition:   Ischemic Stroke
Intervention:  
Sponsor:   Stryker Neurovascular
Recruiting - verified February 2015

Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Canagliflozin, 100 mg;   Drug: Canagliflozin, 300 mg;   Drug: Placebo
Sponsor:   Janssen Research & Development, LLC
Recruiting - verified February 2015

Electrical Pharyngeal Stimulation for Dysphagia Therapy in Tracheostomized Stroke Patients

Conditions:   Stroke;   Dysphagia
Interventions:   Device: Electrical pharyngeal stimulation;   Device: Sham stimulation
Sponsor:   University Hospital Muenster
Completed - verified February 2015

A Registry to Evaluate the Direct Flow Medical Transcatheter Aortic Valve System

Condition:   Aortic Valve Stenosis
Intervention:   Device: Aortic Valve Replacement
Sponsor:   Direct Flow Medical, Inc.
Recruiting - verified February 2015

Solitaire With the Intention For Thrombectomy as PRIMary Endovascular Treatment (SWIFT PRIME) Trial

Condition:   Acute Ischemic Stroke
Interventions:   Drug: intravenous (IV) recombinant human tissue plasminogen activator (rtPA);   Device: Solitaire FR
Sponsor:   Covidien
Completed - verified February 2015

Pilot Study Effect of Sulfasalazine on Glutamate Levels by(Magnetic Resonance Spectroscopy)MRS in Patients With Glioma

Condition:   Brain Tumor
Intervention:   Drug: Sulfasalazine
Sponsor:   University of Alabama at Birmingham
Completed - verified February 2015

A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic Sclerosis

Condition:   Sclerosis, Systemic
Interventions:   Drug: Placebo;   Drug: tocilizumab [RoActemra/Actemra];   Drug: tocilizumab [RoActemra/Actemra]
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified February 2015

Measuring Effects of Alcohol on Brain Chemistry

Condition:   Healthy Volunteers
Intervention:  
Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Terminated - verified February 2015

Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia

Condition:   Cardiac Arrest
Interventions:   Drug: amiodarone;   Drug: Lidocaine;   Other: Normal saline
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research  (CIHR);   Heart and Stroke Foundation of Canada;   American Heart Association;   Defence Research and Development Canada;   U.S. Army Medical Research and Materiel Command
Recruiting - verified February 2015

Magnetic Resonance Biomarkers in Neonatal Encephalopathy

Condition:   Neonatal Encephalopathy
Intervention:  
Sponsor:   Thayyil, Sudhin
Recruiting - verified February 2015

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