Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Belgian Mitraclip Registry

Condition:   Mitral Valve Insufficiency
Intervention:   Device: mitraclip
Sponsor:   Universiteit Antwerpen
Recruiting - verified July 2015

NAFLD in Adolescents and Young Adults With PCOS

Conditions:   Polycystic Ovary Syndrome;   Non-Alcoholic Fatty Liver Disease;   Metabolic Syndrome
Intervention:   Other: There is no intervention
Sponsor:   Columbia University
Recruiting - verified July 2015

Prospective Record Of the Use of Dabigatran in Patients With Acute Stroke or TIA

Conditions:   Brain Ischemia With Non-valvular Atrial Fibrillation;   Transient Ischemic Attack With Non-valvular Atrial Fibrillation
Sponsor:   University Hospital, Essen
Not yet recruiting - verified July 2015

Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin

Conditions:   Aneurysmal Subarachnoid Hemorrhage;   Neurobehavioral Manifestations;   Vasospasm, Intracranial;   Intracranial Aneurysm;   Heparin-induced Thrombocytopenia Type II
Intervention:   Drug: Continuous Low-Dose Intravenous Unfractionated Heparin Infusion (14 days)
Sponsors:   Robert F James, MD, FACS, FAANS;   Brain Aneurysm Foundation;   Microvention-Terumo, Inc.;   Penumbra Inc.;   University of Louisville
Not yet recruiting - verified July 2015

Selenium and Ischemic Stroke Outcome

Condition:   Ischemic Stroke
Interventions:   Drug: Selenium;   Drug: normal saline
Sponsor:   Mazandaran University of Medical Sciences
Not yet recruiting - verified July 2015

Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)

Conditions:   Polycystic Ovary Syndrome;   Non-Alcoholic Fatty Liver Disease;   Metabolic Syndrome
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsor:   Columbia University
Recruiting - verified July 2015

Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis

Conditions:   Scleroderma, Diffuse;   Diffuse Cutaneous Systemic Sclerosis
Interventions:   Drug: IVA337;   Drug: Placebo
Sponsors:   Inventiva Pharma;   Pivotal S.L.;   ATLANBIO;   Unilabs;   ALMAC Clincal Services Ltd;   PHINC DEVELOPMENT;   Talentmark Life Sciences Consulting GmbH;   Nordic Bioscience A/S
Not yet recruiting - verified July 2015

Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain Function

Conditions:   Alzheimer's Disease;   Obesity;   Diabetes Mellitus
Interventions:   Dietary Supplement: Boost A;   Behavioral: Healthy Living Diet
Sponsor:   National Institute on Aging (NIA)
Recruiting - verified April 2015

Study of Hypertrophic Cardiomyopathy Under Stress Conditions. Concordance Between Two Complementary Tests: Stress MRI and Exercice Stress Echocardiography

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Other: Diagnosis examens
Sponsor:   University Hospital, Montpellier
Recruiting - verified July 2015

Acute Normovolemic Hemodilution on ROTEM in Cardiac Surgery

Conditions:   Mitral Regurgitation;   Mitral Stenosis;   Tricuspid Regurgitation
Interventions:   Procedure: Acute normovolemic hemodilution (ANH);   Drug: hydroxyethyl starch (HES 130/0.6)
Sponsor:   Konkuk University Medical Center
Recruiting - verified July 2015

Canadian Study of the MicroVention Flow Re-Direction (FRED) Endoluminal Device Stent System in the Treatment of Intracranial Aneurysms

Condition:   Intracranial Aneurysms
Intervention:   Device: FRED
Sponsor:   Centre hospitalier de l'Université de Montréal (CHUM)
Withdrawn - verified July 2015

Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis

Condition:   Scleroderma, Systemic
Interventions:   Drug: Riociguat (Adempas, BAY63-2521);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified July 2015

Ledipasvir/Sofosbuvir Fixed-Dose Combination on Cerebral Metabolism and Neurocognition in Treatment-Naive and Treatment-Experienced Participants With Chronic Genotype 1 HCV Infection

Condition:   Hepatitis C Virus Infection
Interventions:   Drug: LDV/SOF;   Drug: Placebo to match LDV/SOF
Sponsor:   Gilead Sciences
Active, not recruiting - verified July 2015

Hypnosis to Improve Sleep In Menopause

Condition:   Sleep
Intervention:   Other: Hypnosis
Sponsor:   Baylor University
Active, not recruiting - verified January 2015

Intracerebral Hemorrhage Deferoxamine Trial - iDEF Ttrial

Condition:   Intracerebral Hemorrhage
Interventions:   Drug: Deferoxamine Mesylate;   Drug: Placebo (for Deferoxamine Mesylate)
Sponsors:   Beth Israel Deaconess Medical Center;   Medical University of South Carolina;   National Institute of Neurological Disorders and Stroke (NINDS);   Massachusetts General Hospital;   Tufts Medical Center;   University of Massachusetts, Worcester;   University of Pennsylvania;   Johns Hopkins University;   University of Maryland;   Duke University;   University of North Carolina;   University of Florida;   Henry Ford Hospital;   Ohio State University;   St. Joseph's Hospital and Medical Center, Phoenix;   University of California, San Francisco;   Oregon Health and Science University;   Yale New Haven Health System Center for Healthcare Solutions;   University of Iowa;   Hartford Hospital;   The University of Texas Health Science Center, Houston;   Rhode Island Hospital;   Stanford University;   University of Washington;   University of Calgary, Foothills Hospital;   CHU de Québec - Hôpital de l'Enfant-Jésus;   University of Alberta;   Dalhousie University;   Rush University Medical Center;   University Hospital Case Medical Center;   Columbia University;   Weill Medical College of Cornell University;   New York University Langone Medical Center;   Mount Sinai Hospital, New York
Recruiting - verified July 2015

PERIGON Pivotal Trial

Condition:   Aortic Valve Replacement
Intervention:   Device: Model 400 aortic valve bioprosthesis
Sponsors:   Medtronic Cardiovascular;   Medtronic
Recruiting - verified July 2015

Efficacy and Safety of Sage Tablets Compared to Placebo in Menopausal Patients With Hot Flushes and Sweating

Condition:   Menopausal Hot Flushes
Intervention:   Drug: Sage extract, 3400 mg , DER 1:17
Sponsor:   Bioforce AG
Terminated - verified July 2015

Clinical Management With SPM System and Validation of the SPM 5 Hour Cutoff in Patients With Symptoms of Gastroparesis

Condition:   Gastroparesis
Intervention:   Device: SmartPill Monitoring System
Sponsor:   Medtronic - MITG
Recruiting - verified December 2014

Pacing in First-degree AV-block

Conditions:   First-degree AV-block;   Pacing
Intervention:   Other: Pacing
Sponsors:   Duke University;   Medtronic
Not yet recruiting - verified February 2015

Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions

Condition:   Healthy Volunteers
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified June 2015

Lactate Imaging as a Tumour Biomarker

Condition:   Cancer
Intervention:   Device: Magnetic Resonance Imaging (MRI)
Sponsors:   Institute of Cancer Research, United Kingdom;   Cancer Research UK
Recruiting - verified July 2015

International Subarachnoid Aneurysm Trial II

Condition:   Intracranial Hemorrhage Ruptured Aneurysm
Interventions:   Procedure: surgical management;   Procedure: Endovascular management
Sponsor:   Centre hospitalier de l'Université de Montréal (CHUM)
Recruiting - verified July 2015

Recanalization and Stenting for Non-acute Veterbrobasilar Artery Occlusion

Condition:   Stroke
Intervention:   Device: stenting
Sponsors:   Zhengzhou University;   Henan provincial interventional therapy center;   Henan Provincial Hospital
Recruiting - verified July 2015

PG2 Injection 500 mg in Acute Stroke Study (Pass)

Condition:   Acute Stroke
Interventions:   Drug: PG2;   Drug: placebo
Sponsors:   China Medical University Hospital;   National Taiwan University Hospital;   Shin Kong Wu Ho-Su Memorial Hospital;   Tri-Service General Hospital;   Changhua Christian Hospital;   National Cheng-Kung University Hospital;   Kaohsiung Medical University;   En Chu Kong Hospital;   Kuang Tien General Hospital;   Chung Shan Medical University;   Taipei Veterans General Hospital, Taiwan;   Kaohsiung Veterans General Hospital.;   Taipei Medical University Shuang Ho Hospital;   Cheng Hsin Rehabilitation Medical Center;   Taipei Medical University WanFang Hospital
Active, not recruiting - verified July 2015

Optimization of Treatment and Management of Schizophrenia in Europe

Conditions:   Schizophrenia;   Schizophreniform Disorder;   Schizoaffective Disorder
Interventions:   Drug: Amisulpride open label;   Drug: 6-week amisulpride double blind treatment;   Drug: 6-week olanzapine double blind treatment;   Drug: 12-week clozapine open-label treatment;   Behavioral: Psychosocial intervention
Sponsors:   Rene Kahn;   King's College London;   Technische Universität München;   University of Manchester;   Ludwig-Maximilians - University of Munich
Recruiting - verified July 2015

Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)

Condition:   Diffuse Intrinsic Pontine Glioma
Interventions:   Drug: Bevacizumab;   Drug: Erlotinib;   Drug: Temozolomide;   Radiation: Irradiation
Sponsors:   Dana-Farber Cancer Institute;   Children's Hospital Boston;   University of California, San Francisco;   Ann & Robert H Lurie Children's Hospital of Chicago;   Children's Healthcare of Atlanta;   Children's Hospital Colorado;   Children's Hospital Los Angeles;   Children's Hospital of Michigan;   Children's Hospitals and Clinics of Minnesota;   Cook Children's Medical Center;   Doernbecher Children's Hospital;   Duke University;   Johns Hopkins University;   Miami Children's Hospital;   Nemours Children's Clinic Jacksonville;   New York University;   Milton S. Hershey Medical Center;   Seattle Children's;   Lucile Packard Children's Hospital;   University of Louisville;   UT Southwestern Medical Center;   Washington University School of Medicine;   Phoenix Children's Hospital;   Medical University of South Carolina
Recruiting - verified April 2015

EASE MITRAL Expertise-based Assessment Study on Clinical Efficacy of Profile 3D in MITRAL Valve Annuloplasty

Condition:   Mitral Valve Insufficiency
Sponsor:   Medtronic Bakken Research Center
Active, not recruiting - verified July 2015

University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial)

Conditions:   Nonalcoholic Steatohepatitis;   Nonalcoholic Fatty Liver Disease;   Type 2 Diabetes Mellitus
Interventions:   Drug: Pioglitazone;   Drug: Placebo;   Drug: Pioglitazone;   Drug: Placebo
Sponsors:   University of Florida;   The University of Texas at San Antonio
Completed - verified July 2015

Development of Applications of the Given® Diagnostic System and Evaluation of Their Performance

Condition:   Healthy
Sponsor:   Given Imaging Ltd.
Recruiting - verified July 2015

Torsion Optimization to Reduce Symptoms and Improve Outcomes in Non-responders

Condition:   Heart Failure, Congestive
Interventions:   Other: Torsion optimized;   Other: Usual Care
Sponsors:   University of Calgary;   Heart and Stroke Foundation of Canada
Active, not recruiting - verified July 2015

Impact of GABA-Enhancing Agents on Cortical GABA Concentrations Across the Menstrual Cycle in Women

Condition:   Healthy
Interventions:   Drug: Fluoxetine;   Drug: Zolpidem;   Drug: Progesterone
Sponsor:   Yale University
Completed - verified July 2015

Dynamic Contrast Enhanced MRI (DCE-MRI) Diffusion Weighted MRI (DW-MRI) and Magnetic Resonance Spectroscopy (MRS) of Head and Neck Tumors

Condition:   Head and Neck Cancer
Intervention:   Radiation: DCE-MRI,  DW-MRI and MRS
Sponsors:   Memorial Sloan Kettering Cancer Center;   National Institutes of Health (NIH)
Recruiting - verified July 2015

Diagnostic Procedures in Women With Locally Advanced Breast Cancer Who Are Receiving Chemotherapy Before Breast Cancer Surgery

Condition:   Breast Cancer
Interventions:   Procedure: biopsy;   Procedure: magnetic resonance imaging;   Procedure: radiomammography;   Procedure: ultrasound imaging;   Radiation: gadopentetate dimeglumine;   Drug: chemotherapy
Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI)
Active, not recruiting - verified July 2015

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