Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

MRS and Medication Response: A Pilot Study

Conditions:   Major Depressive Disorder;   Major Depressive Episode;   Major Depressive Disorder, Recurrent;   Major Depression Mild;   Major Depression Moderate;   Major Depression Severe
Intervention:  
Sponsor:   Stanford University
Recruiting - verified August 2017

Ketogenic Diet (KD) in Alcoholism

Condition:   Alcoholism
Interventions:   Dietary Supplement: Ketogenic Diet (KD);   Dietary Supplement: Standard American (SA) Meals and Shakes
Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 10, 2017

SC IL-1Ra in SAH - Phase III Trial (SCIL)

Condition:   Subarachnoid Hemorrhage
Interventions:   Drug: IL-1Ra;   Drug: IL-1Ra Placebo
Sponsors:   University of Manchester;   National Institute for Health Research, United Kingdom;   Manchester Academic Health Science Centre;   Salford Royal NHS Foundation Trust;   University Hospital of South Manchester NHS Foundation Trust
Not yet recruiting - verified August 2017

Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke

Condition:   Stroke
Interventions:   Drug: Alprostadil;   Drug: Normal saline
Sponsor:   First Hospital of Jilin University
Not yet recruiting - verified August 2017

Evaluate the Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia

Condition:   Fibromyalgia
Interventions:   Drug: NYX-2925;   Drug: Placebo oral capsule
Sponsors:   Aptinyx;   inVentiv Health Clinical
Not yet recruiting - verified August 2017

Ruptured Aneurysms Treated With Hydrogel Coils

Condition:   Ruptured Aneurysm
Intervention:   Device: Second-generation hydrogel coils
Sponsors:   Microvention-Terumo, Inc.;   Semmes-Murphey Foundation
Not yet recruiting - verified August 2017

Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients

Conditions:   Healthy;   Mild Cognitive Impairment;   Alzheimer Disease
Interventions:   Device: real anodal transcranial direct current stimulation (tDCS);   Device: sham transcranial direct current stimulation (tDCS)
Sponsor:   University of Bern
Not yet recruiting - verified August 2017

Efficacy and Safety of Oral Testosterone Undecanoate in Hypogonadal Men

Condition:   Hypogonadism, Male
Interventions:   Drug: SOV2012-F1;   Drug: AndroGel
Sponsors:   Marius Pharmaceuticals;   INC Research
Recruiting - verified June 2017

Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)

Conditions:   Functional Mitral Regurgitation;   Mitral Regurgitation;   Mitral Insufficiency
Intervention:   Device: Edwards Cardioband System
Sponsor:   Edwards Lifesciences
Recruiting - verified August 2017

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

Condition:   Mitral Valve Failure
Interventions:   Device: Edwards SAPIEN 3 transcatheter heart valve;   Device: ASHI INTECC Astato XS 20
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified August 18, 2017

Inhaled Nitric Oxide After Out-of-Hospital Cardiac Arrest

Condition:   Heart Arrest, Out-Of-Hospital
Interventions:   Drug: Nitric Oxide;   Drug: Nitrogen
Sponsors:   Cameron Dezfulian;   Mallinckrodt
Not yet recruiting - verified August 2017

Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic Sclerosis

Condition:   Systemic Sclerosis
Interventions:   Drug: SAR156597 (ACT14604);   Drug: Placebo
Sponsor:   Sanofi
Recruiting - verified August 2017

Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair

Condition:   Mitral Valve Insufficiency
Interventions:   Device: NeoChord DS1000;   Device: Surgical Mitral Valve Repair
Sponsor:   NeoChord
Recruiting - verified October 2016

Safety and Efficacy of Two Doses of SP-8203 in Patients With Ischemic Stroke Requiring rtPA

Condition:   Ischemic Stroke
Interventions:   Drug: SP-8203 High dose;   Drug: SP-8203 Low dose;   Drug: Placebo
Sponsor:   Shin Poong Pharmaceutical Co. Ltd.
Active, not recruiting - verified January 2017

Positron Emission Tomography Assessment of Ketamine Binding of the Serotonin Transporter

Conditions:   Depression;   Ketamine
Interventions:   Drug: (S)-ketamine (Main study);   Drug: (S)-ketamine (Pilot II);   Drug: (R,S)-ketamine (Pilot II);   Drug: Placebo;   Other: PILOT Study II: PET1;   Other: PILOT Study II: PET2;   Other: Main Study: PET1;   Other: Main Study: PET2;   Other: PILOT Study I: PET1;   Other: PILOT Study I: PET2;   Drug: (R,S)-ketamine (Pilot I);   Drug: (R,S)-ketamine (Pilot III);   Other: PILOT Study III: PET1;   Other: PILOT Study III: PET2
Sponsor:   Medical University of Vienna
Recruiting - verified August 2017

Electromyographic Activity of Preterm Newborns Submitted to Hammock Positioning

Condition:   Infant, Premature, Diseases
Intervention:   Other: Hammock positioning
Sponsor:   Instituto Materno Infantil Prof. Fernando Figueira
Active, not recruiting - verified August 2017

The Capillary Index Score Trial

Conditions:   Acute Stroke;   Brain Ischemia;   Ischemic Stroke
Intervention:   Procedure: Endovascular Treatment (EVT)
Sponsors:   Firas Al-Ali;   Stryker Neurovascular;   Rochester General Hospital;   University of Vermont Medical Center;   University of North Carolina, Chapel Hill;   New York University Langone Medical Center
Enrolling by invitation - verified August 2017

Annular Reshaping of the Mitral Valve for MR Using the Millipede IRIS System

Condition:   Mitral Valve Insufficiency
Intervention:   Device: Mitral Valve IRIS Ring
Sponsors:   Millipede Inc.;   Meditrial Europe Ltd.
Recruiting - verified August 2017

A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis

Condition:   Scleroderma, Systemic
Interventions:   Drug: Nintedanib;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion
Recruiting - verified February 2017

BestFIT: a Personalized Weight Loss Program

Condition:   Obesity
Interventions:   Behavioral: Behavioral weight loss therapy;   Behavioral: Meal replacements;   Behavioral: Enhanced behavioral weight loss therapy
Sponsors:   HealthPartners Institute;   Drexel University;   University of Michigan;   University of Minnesota - Clinical and Translational Science Institute;   University of Washington;   National Cancer Institute (NCI)
Recruiting - verified August 2017

Trial of Topical C-82 in Systemic Sclerosis - A Phase I/II Biomarker and Safety Trial

Condition:   Systemic Scleroderma
Interventions:   Drug: C-82 Topical Gel, 1%;   Drug: C-82 Topical Gel, Placebo
Sponsor:   Prism Pharma Co., Ltd.
Completed - verified September 2016

Stress Echocardiography Versus Exercise ECG (ExECG) in Women With Chest Pain

Condition:   Coronary Artery Disease
Interventions:   Procedure: Exercise ECG;   Procedure: Stress Echocardiography
Sponsor:   London North West Healthcare NHS Trust
Recruiting - verified March 2017

Neurocognitive and Radiological Assessments in Adult Moyamoya Undergoing Surgery

Condition:   Moyamoya Disease
Interventions:   Procedure: Surgical Revascularization;   Other: Conservative treatment
Sponsor:   Huashan Hospital
Recruiting - verified August 2017

MEG Study of STX209

Condition:   Autism Disorder
Interventions:   Drug: STX209;   Drug: placebo
Sponsors:   Children's Hospital of Philadelphia;   Simons Foundation;   Clinical Research Associates, LLC
Recruiting - verified August 2017

Acupuncture for Cerebral Vasospasm After Subarachnoid Hemorrhage

Conditions:   SAH (Subarachnoid Hemorrhage);   Cerebral Vasospasm
Interventions:   Device: acupuncture;   Device: Electroacupuncture;   Device: Intradermal acupuncture;   Device: Mock transcutaneous electrical nerve stimulation;   Device: sham intradermal acupuncture
Sponsor:   Kyung Hee University Hospital at Gangdong
Completed - verified August 2017