Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

High Quality Protein for Assisting With Weight Loss

Condition:   Obesity
Interventions:   Behavioral: Egg breakfast (EB);   Behavioral: Weight Loss Counseling;   Behavioral: Weight Loss Diet;   Behavioral: Cereal Breakfast (CB)
Sponsors:   Texas Tech University;   American Egg Board
Not yet recruiting - verified March 2017

Effect of External Counter Pulsation on Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:   Device: External counter pulsation (ECP)
Sponsors:   Eighth Affiliated Hospital, Sun Yat-sen University;   Shenzhen Research Institute, The Chinese University Hong Kong;   Second Affiliated Hospital of Xi'an Jiaotong University;   The Second Affiliated Hospital of Zhengzhou University
Not yet recruiting - verified March 2017

Intranasal Insulin for the Treatment of HAND

Conditions:   HIV Dementia;   HIV-Associated Cognitive Motor Complex
Interventions:   Drug: Insulin, intranasal;   Drug: Placebo, intranasal
Sponsor:   Johns Hopkins University
Recruiting - verified March 2017

Long Term Follow Up for CTSN Mitral Valve Repair Studies

Conditions:   Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions:   Other: MV Repair;   Other: MV Replacement;   Other: CABG
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR)
Not yet recruiting - verified March 2017

Stress Echo 2020 - The International Stress Echo Study

Conditions:   Coronary Artery Disease;   Heart Failure;   Hypertrophic Cardiomyopathy;   Aortic Valve Disease;   Athletes Heart;   Tetralogy of Fallot;   Pulmonary Arterial Hypertension
Interventions:   Procedure: Left ventricular contractile reserve SE;   Procedure: B-lines SE;   Procedure: Left ventricular outflow tract gradient SE;   Procedure: Diastolic function SE;   Procedure: Mitral regurgitation SE;   Procedure: Pulmonary hemodynamics SE;   Procedure: Coronary flow reserve SE
Sponsors:   Fatebenefratelli Hospital;   Institute of Clinical Physiology, CNR, Pisa,Italy;   Salerno Hospital, Italy;   Monaldi Hospital, Napoli, Italy;   University of Pisa, Italy;   San Luca Hospital, Lucca, Italy;   Careggi University Hospital, Florence, Italy;   Federico II University, Napoli, Italy;   San Carlo Hospital, Potenza, Italy;   Royal Brompton & Harefield NHS Foundation Trust;   Ospedale dell'Angelo, Venezia-Mestre, Italy;   University of Parma;   Hospital Clinics, Trieste, Italy;   Hospital de Clinicas de Porto Alegre - Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil;   Hospital San José, Criciuma, Brasil;   Hospital San Vicente de Paulo, Passo Fundo, Brasil;   University of Belgrade;   University of Szeged, Hungary;   Elisabeth Hospital, Hodmezovasarhely, Hungary;   University of Padua, Italy;   Sandro Pertini Hospital, Rome, Italy;   Medical Center Hospital of the Republic of Kazakhstan, Astana, Kazakhstan;   Hospital Clinics, Bari, Italy;   Ospedale Nottola, Siena, Italy;   University of Catania, Italy;   Medika Cardiocenter, Saint Petersburg, Russian Federation
Recruiting - verified February 2017

Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke

Conditions:   Stroke;   Stroke, Acute;   Brain Injury, Acute
Interventions:   Biological: Umbilical Cord Blood;   Other: Placebo
Sponsors:   Joanne Kurtzberg, MD;   The Marcus Foundation;   Emory University;   M.D. Anderson Cancer Center
Recruiting - verified March 2017

Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic Sclerosis

Condition:   Systemic Sclerosis
Interventions:   Drug: SAR156597 (ACT14604);   Drug: Placebo
Sponsor:   Sanofi
Recruiting - verified March 2017

A Study to Evaluate the Safety and Efficacy of Basmisanil in Adults With Severe Motor Impairment Following an Ischemic Stroke

Condition:   Stroke
Interventions:   Drug: Basmisanil;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Recruiting - verified March 2017

Mechanisms of Diastolic Dysfunction Among Persons With HIV Compared With Non-HIV Control Subjects

Conditions:   HIV;   Diastolic Dysfunction;   Myocardial Fibrosis
Intervention:   Other: Cardiac MRI/MRS
Sponsors:   Massachusetts General Hospital;   President and Fellows of Harvard College
Recruiting - verified March 2017

ENRICH: Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ICH)

Conditions:   Intracerebral Hemorrhage;   Cerebral Hemorrhage;   Intracerebral Haemorrhage
Intervention:   Procedure: Early Surgical Hematoma Evacuation
Sponsors:   Nico Corporation;   Emory University
Recruiting - verified March 2017

Efficacy and Safety Study of CNTO 2476 in Participants With Visual Acuity Impairment Associated With Geographic Atrophy (GA) Secondary to Age Related Macular Degeneration (AMD)

Conditions:   Visual Acuity;   Geographic Atrophy;   Macular Degeneration
Interventions:   Drug: CNTO 2476 (6.0 x 10^4 cells);   Drug: CNTO 2476 (3.0 x 10^5 cells)
Sponsor:   Janssen Pharmaceutical K.K.
Not yet recruiting - verified March 2017

Clinical Trial to Assess the Efficacy and to Evaluate Safety of HT047 in Patients With Acute Ischemic Stroke

Condition:   Ischemic Stroke
Interventions:   Drug: HT047 High-dose group;   Drug: HT047 Low-dose group;   Drug: Placebo
Sponsor:   Hocheol Kim
Recruiting - verified March 2017

A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes

Condition:   Ischemic Stroke
Intervention:   Drug: TF0023
Sponsor:   Techfields Inc
Recruiting - verified November 2016

Safety and Performance of the Accucinch System

Conditions:   Heart Failure;   Mitral Valve Insufficiency
Intervention:   Device: Accucinch Implant
Sponsor:   Ancora Heart, Inc.
Withdrawn - verified March 2017

A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis

Condition:   Scleroderma, Systemic
Interventions:   Drug: Nintedanib;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Recruiting - verified March 2017

Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain Function

Conditions:   Alzheimer's Disease;   Obesity;   Diabetes Mellitus
Interventions:   Dietary Supplement: Boost A;   Behavioral: Healthy Living Diet
Sponsor:   National Institute on Aging (NIA)
Recruiting - verified February 8, 2017

A Comparative Phase 2 Study Assessing the Efficacy of Triheptanoin, an Anaplerotic Therapy in Huntington's Disease

Condition:   Huntington Disease
Interventions:   Drug: Triheptanoin oil;   Drug: Placebo
Sponsors:   Institut National de la Santé Et de la Recherche Médicale, France;   Ultragenyx Pharmaceutical Inc
Recruiting - verified March 2017

Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis

Condition:   Scleroderma, Systemic
Interventions:   Drug: Riociguat (Adempas, BAY63-2521);   Drug: Placebo
Sponsor:   Bayer
Active, not recruiting - verified March 2017

Dairy Intake and Brain Health in Aging

Condition:   Aged Healthy Volunteer
Intervention:  
Sponsors:   University of Kansas Medical Center;   National Dairy Council
Completed - verified March 2017

Repetitive Transcranial Magnetic Stimulation Equipment Testing and Pilot Study

Condition:   Healthy Volunteer
Intervention:   Device: TMS
Sponsor:   National Institute on Drug Abuse (NIDA)
Recruiting - verified February 8, 2017

Vitamin D and Muscle Metabolic Function

Condition:   Healthy
Interventions:   Dietary Supplement: vitamin D;   Other: aerobic training
Sponsor:   David Travis Thomas
Recruiting - verified March 2017

A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis

Condition:   Diffuse Cutaneous Systemic Sclerosis
Interventions:   Drug: Abatacept;   Drug: Placebo
Sponsors:   Dinesh Khanna, MD, MS;   Bristol-Myers Squibb;   National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting - verified March 2017

Behavioral and Neural Response to Memantine in Adolescents With Autism Spectrum Disorder

Condition:   Autism Spectrum Disorder
Interventions:   Drug: Memantine;   Drug: Placebo
Sponsors:   Massachusetts General Hospital;   Mclean Hospital
Recruiting - verified March 2017

Attenuation of Corticosteroid Induced Hippocampal Changes

Condition:   Organic Memory Impairment
Interventions:   Drug: Memantine;   Drug: Placebo
Sponsors:   University of Texas Southwestern Medical Center;   National Institute on Drug Abuse (NIDA)
Active, not recruiting - verified March 2017

Nicotine Withdrawal Symptoms and Smoking Relapse

Condition:   Nicotine Dependence
Intervention:  
Sponsor:   National Institute on Drug Abuse (NIDA)
Recruiting - verified January 30, 2017

DaTSCAN Imaging in Aging and Neurodegenerative Disease

Conditions:   Dementia;   Parkinsonism;   Mild Cognitive Impairment;   REM Sleep Behavior Disorder
Interventions:   Drug: I-123 Ioflupane solution injection prior to SPECT scan (DaTscan);   Device: Single photon emission computed tomography (SPECT) scan
Sponsor:   Mayo Clinic
Enrolling by invitation - verified March 2017

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

Conditions:   Brain Mapping;   Healthy Volunteer
Intervention:  
Sponsor:   National Institute of Mental Health (NIMH)
Recruiting - verified February 27, 2017

Nicotine and Brain Imaging Research Study

Condition:   Nicotine
Intervention:  
Sponsor:   University of Pennsylvania
Active, not recruiting - verified March 2017

A Study of Percutaneous Treatment of Mitral Regurgitation Using the AccuCinch® System

Conditions:   Mitral Regurgitation;   Mitral Valve Regurgitation;   Functional Mitral Regurgitation
Intervention:   Device: GDS Accucinch® System
Sponsor:   Ancora Heart, Inc.
Recruiting - verified March 2017

Hematopoietic Stem Cell Transplant in Devic's Disease

Condition:   Devic's Disease
Intervention:   Procedure: Hematopoietic stem cell transplantation
Sponsor:   Northwestern University
Recruiting - verified March 2017

Efficacy and Tolerability of STI571 (Imatinib Mesylate) for the Treatment of Fibrosis in Patients With Systemic Sclerosis

Condition:   Systemic Sclerosis, Scleroderma
Intervention:   Drug: STI571
Sponsor:   Novartis Pharmaceuticals
Completed - verified March 2017

Role of p53 Gene in Metabolism Regulation in Patients With Li-Fraumeni Syndrome

Condition:   Li-Fraumeni Syndrome
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified February 27, 2017

Comparing Magnetic Resonance Imaging/Spectroscopy Techniques

Condition:   MRI Scans
Intervention:  
Sponsor:   National Institutes of Health Clinical Center (CC)
Enrolling by invitation - verified March 7, 2017