Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Safety and Efficacy of Alteplase When Administered in Chinese Patients With Acute Ischemic Hemispheric Stroke Where Thrombolysis is Initiated Between 3 and 4.5 Hours After Stroke Onset

Condition:   Stroke
Intervention:   Drug: alteplase
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified September 2016

Observational Study of Males With Creatine Transporter Deficiency

Condition:   Creatine Deficiency, X-linked
Sponsors:   Lumos Pharma;   Premier Research Group plc
Recruiting - verified October 2016

Integrating Quantitative Energetics Determines the Microbiome's Contribution to Energy Balance

Condition:   Obesity
Interventions:   Other: Dual-energy X-ray absorptiometry (DEXA)/ Magnetic resonance spectroscopy (MRS);   Other: 23-hour Metabolic Calorimetry;   Other: Whole Room Calorimetry;   Other: Polyethylene glycol (PEG)
Sponsors:   Translational Research Institute for Metabolism and Diabetes, Florida;   Arizona State University;   Pennington Biomedical Research Center;   University of Florida
Not yet recruiting - verified October 2016

Management and Clinical Outcomes of Patients With Severe Mitral Valve Disease Not Suitable for Surgery

Condition:   Mitral Valve Disease
Sponsor:   French Cardiology Society
Recruiting - verified October 2016

Effect of a Single Session of rTMS on Brain Response to Cues in Polysubstance Users

Condition:   Substance Abuse
Interventions:   Device: cTBS (real);   Device: cTBS (sham)
Sponsor:   Medical University of South Carolina
Completed - verified August 2016

Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders

Condition:   Urea Cycle Disorders
Interventions:   Procedure: MRI;   Behavioral: Behavioral
Sponsors:   Children's Research Institute;   Boston Children’s Hospital
Recruiting - verified October 2016

Multifocal Brain Magnetic Stimulation in Chronic Ischemic Stroke

Condition:   Stroke
Intervention:   Device: Transcranial magnetic stimulation
Sponsors:   David Chiu, MD;   The Methodist Hospital System
Enrolling by invitation - verified October 2016

Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: natalizumab;   Drug: Placebo
Sponsor:   Biogen
Recruiting - verified October 2016

Clinical Development of MR Spectroscopy and Imaging in Brain Cancers

Conditions:   Malignant Gliomas;   Astrocytomas;   Oligodendrogliomas
Interventions:   Device: 3 Tesla Scanning;   Device: 7 Tesla Scanning
Sponsors:   University of Texas Southwestern Medical Center;   Cancer Prevention Research Institute of Texas
Recruiting - verified October 2016

S100 Biomarker in the Acute Management of Mild Head Injuries

Conditions:   Brain Injury;   Head Injury
Intervention:   Other: Indications for head CT imaging after acute head injury
Sponsors:   Tampere University Hospital;   Harvard Medical School;   Turku University Hospital
Recruiting - verified October 2016

Ketamine Infusion in Neurologic Deficit

Condition:   Subarachnoid Hemorrhage
Interventions:   Drug: Ketamine;   Drug: 0.9% NaCl
Sponsors:   Dr. Andrew Baker;   Defence Research and Development Canada
Recruiting - verified October 2016

The Capillary Index Score Trial

Conditions:   Acute Stroke;   Brain Ischemia;   Ischemic Stroke
Intervention:   Procedure: Endovascular Treatment (EVT)
Sponsors:   Firas Al-Ali;   Stryker Neurovascular;   University of Rochester;   University of Vermont Medical Center;   University of North Carolina, Chapel Hill;   New York University Langone Medical Center
Enrolling by invitation - verified October 2016

Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical Treatment

Conditions:   Stroke Due to Basilar Artery Occlusion;   Acute Cerebrovascular Accidents
Interventions:   Device: endovascular treatment;   Other: standard medical therapy
Sponsor:   Xinfeng Liu
Recruiting - verified August 2016

Inflammation-Induced CNS Glutamate During Breast Cancer Treatment

Condition:   Breast Cancer
Sponsor:   Emory University
Recruiting - verified October 2016

Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas

Conditions:   Malignant Gliomas;   Oligodendrogliomas;   Astrocytomas
Intervention:   Device: 3 Tesla scanning
Sponsors:   University of Texas Southwestern Medical Center;   National Institutes of Health (NIH);   National Cancer Institute (NCI)
Recruiting - verified October 2016

CARILLON Mitral Contour System® for Reducing Functional Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Heart Failure
Intervention:   Device: CARILLON Mitral Contour System
Sponsors:   Cardiac Dimensions Pty Ltd;   Menzies Institute for Medical Research
Recruiting - verified October 2016

Head Position in Stroke Trial (HeadPoST)

Conditions:   Ischemic Stroke;   Intracerebral Haemorrhage
Interventions:   Other: The lying flat (0°) head position for 24 hours;   Other: The sitting-up (≥30°) head position for 24 hours
Sponsors:   The George Institute;   National Health and Medical Research Council, Australia
Active, not recruiting - verified October 2016

PERIGON Pivotal Trial

Condition:   Aortic Stenosis
Intervention:   Device: Model 400 aortic valve bioprosthesis
Sponsors:   Medtronic Cardiovascular;   Medtronic
Recruiting - verified October 2016

MitraClip® Registry

Condition:   Mitral Regurgitation
Sponsor:   Klinik für Kardiologie, Pneumologie und Angiologie
Recruiting - verified October 2016

Trevo® Retriever Registry Post Market Surveillance

Condition:   Ischemic Stroke
Sponsor:   Stryker Neurovascular
Recruiting - verified October 2016

Preoperative Staging and Dose Escalated Radiotherapy of Prostate Carcinoma With PET and MRI

Condition:   Prostate Carcinoma
Intervention:   Device: PET/CT, PET/MRI, mpMRI
Sponsors:   Turku University Hospital;   GE Healthcare;   Blue Earth Diagnostics
Completed - verified October 2016

Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions

Condition:   Healthy Volunteers
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified October 2016

Mitralign Percutaneous Annuloplasty System for Chronic Functional Mitral Valve Regurgitation

Condition:   Mitral Valve Regurgitation
Intervention:   Device: percutaneous annuloplasty
Sponsor:   Mitralign, Inc.
Active, not recruiting - verified October 2016

Efficacy and Safety of Passiflora Incarnata and Isoflavona Combination in the Treatment of Climacteric Symptoms

Condition:   Climacteric Syndrome
Interventions:   Drug: Placebo;   Drug: Active drug
Sponsor:   Ache Laboratorios Farmaceuticos S.A.
Withdrawn - verified October 2016

Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD

Condition:   Obsessive Compulsive Disorder
Interventions:   Drug: Minocycline;   Other: Placebo
Sponsors:   New York State Psychiatric Institute;   National Institute of Mental Health (NIMH);   Weill Medical College of Cornell University
Recruiting - verified October 2016

Danhong Injection in the Treatment of Acute Ischemic Stroke

Condition:   Acute Stroke
Interventions:   Drug: Danhong injection;   Procedure: Standard medical care;   Drug: placebo
Sponsors:   China Academy of Chinese Medical Sciences;   China Food and Drug Administration
Recruiting - verified October 2016

CArdiac Desynchronization In Obstructive HCM, CARDIO-HCM

Condition:   Hypertrophic Obstructive Cardiomyopathy (HOCM)
Interventions:   Device: Biventricular pacing;   Device: No Pacing
Sponsor:   Hospital Clinic of Barcelona
Recruiting - verified October 2016

Quantitative Imaging and Proton Spectroscopy in Multiple Sclerosis

Condition:   Multiple Sclerosis
Intervention:   Device: Magnetic Resonance Imaging
Sponsors:   New York University School of Medicine;   National Institute of Neurological Disorders and Stroke (NINDS)
Terminated - verified October 2016