Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

MRSI Guided Dose Escalated Radiation in Glioblastoma

Condition:   Glioblastoma
Interventions:   Radiation: Intensity Modulated Radiation Therapy;   Drug: Temozolomide;   Device: Three Dimensional Volumetric MRS Imaging;   Behavioral: FACT-BR Questionnaire;   Radiation: Stereotactic Radiosurgery Boost;   Radiation: Simultaneous Integrated Boost;   Device: MRI
Sponsor:   University of Miami
Not yet recruiting - verified March 2015

A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion

Condition:   Stroke, Acute
Interventions:   Drug: Tenecteplase;   Drug: Antiplatelet treatment
Sponsor:   University of Calgary
Not yet recruiting - verified March 2015

A Study of Bezafibrate in Mitochondrial Myopathy

Condition:   Mitochondrial Diseases
Intervention:   Drug: Bezafibrate
Sponsors:   Newcastle-upon-Tyne Hospitals NHS Trust;   Newcastle University
Not yet recruiting - verified March 2015

A Multicenter, Randomized, Controlled Study to Assess Mitral vAlve reconsTrucTion for advancEd Insufficiency of Functional or iscHemic ORigiN

Condition:   Mitral Valve Insufficiency
Interventions:   Device: MitraClip system (Abbott Vascular, Menlo Park, USA);   Procedure: Reconstructive mitral valve surgery
Sponsors:   Universitätsklinikum Köln ;   Clinical Trials Center Cologne
Recruiting - verified February 2015

Metabolic Anomolies Associated With the 6 Month Clinical Evolution of Patients Suffering From Motor Conversion Disorder

Condition:   Conversion Disorder
Intervention:   Device: PET CT 18 FDG
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified March 2015

CNS Uptake of Intranasal Glutathione

Condition:   Parkinson's Disease
Intervention:   Drug: Reduced Glutathione
Sponsors:   University of Washington;   Michael J. Fox Foundation for Parkinson's Research
Active, not recruiting - verified December 2014

Field Randomization of NA-1 Therapy in Early Responders

Condition:   Acute Cerebral Ischemia
Interventions:   Drug: NA-1;   Drug: Placebo
Sponsors:   NoNO Inc.;   Brain Canada;   Djavad Mowafaghian Centre for Brain Health;   Canadian Stroke Network;   St. Michael's Hospital, Toronto;   Sunnybrook Health Sciences Centre;   University Health Network, Toronto;   Trillium Health Centre;   Vancouver General Hospital;   University of Calgary;   Dalhousie University;   University of Toronto;   University of British Columbia
Recruiting - verified March 2015

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System

Condition:   Mitral Valve Regurgitation
Intervention:   Device: Mitral valve replacement
Sponsor:   Neovasc Inc.
Recruiting - verified March 2015

Decompressive Hemicraniectomy in Intracerebral Hemorrhage

Condition:   Cerebral Hemorrhage
Interventions:   Procedure: Decompressive craniectomy (DC) and best medical treatment;   Procedure: Best medical treatment
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified March 2015

Assessment of Cardiopulmonary Function in Duchenne Muscular Dystrophy

Condition:   Muscular Dystrophy, Duchenne
Interventions:   Other: Magnetic Resonance Imaging (MRI);   Other: Pulmonary Function Testing (PFT);   Other: Metabolic Exercise Testing using stationary bicycle;   Other: Echocardiogram
Sponsor:   University of Florida
Recruiting - verified March 2015

Biomarker Assessment of Glutamatergic Target Engagement

Condition:   Healthy Controls
Interventions:   Drug: Ketamine;   Drug: Normal saline
Sponsors:   New York State Psychiatric Institute;   National Institute of Mental Health (NIMH)
Recruiting - verified March 2015

Helsinki Ultra-acute Stroke Biomarker Study

Condition:   Acute Stroke
Intervention:  
Sponsors:   Helsinki University Central Hospital;   HUS area Prehospital Emergency Service
Recruiting - verified March 2015

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)

Condition:   Brain Ischemia
Interventions:   Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
Sponsor:   Genentech, Inc.
Recruiting - verified March 2015

MitraClip® Registry

Condition:   Mitral Regurgitation
Intervention:  
Sponsor:   Klinik für Kardiologie, Pneumologie und Angiologie
Recruiting - verified March 2015

Compound Edaravone Injection for Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: Compound Edaravone Injection;   Drug: Edaravone Injection
Sponsor:   Jiangsu Simcere Pharmaceutical Co., Ltd.
Completed - verified March 2015

Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma

Condition:   Malignant Pleural Mesothelioma
Interventions:   Drug: defactinib (VS-6063);   Drug: Placebo
Sponsor:   Verastem, Inc.
Recruiting - verified March 2015

NMDA Antagonists in Bipolar Depression

Condition:   Bipolar Disorder
Interventions:   Drug: Standard of Care;   Drug: Ketamine;   Drug: D-cycloserine
Sponsor:   New York State Psychiatric Institute
Recruiting - verified March 2015

Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:   Procedure: Endovascular thrombectomy/thrombolysis
Sponsors:   University of Calgary;   Covidien;   Heart and Stroke Foundation of Canada;   Hotchkiss Brain Institute, University of Calgary
Terminated - verified March 2015

Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD

Condition:   Obsessive Compulsive Disorder
Interventions:   Drug: Minocycline;   Other: Placebo
Sponsors:   New York State Psychiatric Institute;   National Institute of Mental Health (NIMH);   Weill Medical College of Cornell University
Recruiting - verified March 2015

Magnetic Resonance Spectroscopy in Autonomic Failure

Conditions:   Pure Autonomic Failure;   Multiple System Atrophy
Intervention:   Procedure: Magnetic Resonance Spectroscopy Imaging
Sponsor:   Vanderbilt University
Recruiting - verified March 2015

Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation

Condition:   Prostate Cancer
Interventions:   Drug: Standard of care ADT + (HMB + arginine + glutamine);   Other: Standard of care ADT
Sponsor:   Medical College of Wisconsin
Recruiting - verified March 2015

Biomarkers in Aortic Stenosis - B.A.S.S.

Conditions:   Aortic Stenosis;   Disorder of Prosthetic Cardiac Valve;   Aortic Valve Insufficiency;   Mitral Valve Insufficiency;   Hypertrophic Cardiomyopathy;   Tricuspid Valve Insufficiency
Interventions:   Procedure: Blood Draw;   Other: Blood draw
Sponsor:   Mayo Clinic
Recruiting - verified March 2015

Clinical effecT of Heart Failure Management Via Home Monitoring With a Focus on Atrial Fibrillation (effecT)

Conditions:   Heart Failure;   Atrial Fibrillation
Interventions:   Device: Home Monitoring (Cardiac resynchronization therapy and atrial fibrillation therapy with Home Monitoring feature);   Device: Home Monitoring (Cardiac resynchronization therapy and atrial fibrillation therapy, without Home Monitoring)
Sponsor:   Biotronik SE & Co. KG
Suspended - verified March 2015

Magnetic Resonance Spectroscopy, Perfusion, and Diffusion Tensor Imaging in Neuropsychiatric Lupus

Condition:   Neuropsychiatric Systemic Lupus Erythematosus
Interventions:   Procedure: Magnetic Resonance Angiography (MRA);   Procedure: Magnetic resonance imaging;   Procedure: MRA;   Procedure: MRA;   Procedure: diffusion Imaging;   Procedure: perfusion imaging.
Sponsor:   University of Michigan
Completed - verified March 2015

An fMRI Study of Self-regulation in Adolescents With Bulimia Nervosa

Condition:   Eating Disorders
Interventions:   Other: MRI;   Behavioral: Neuropsychological Testing
Sponsors:   New York State Psychiatric Institute;   National Institute of Mental Health (NIMH)
Active, not recruiting - verified March 2015

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