Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI

Condition:   Glioblastoma
Interventions:   Radiation: Avastin;   Radiation: Lomustine;   Radiation: Temozolomide;   Device: MRI;   Device: MRS;   Device: DSC
Sponsor:   Massachusetts General Hospital
Not yet recruiting - verified July 2016

3D Echocardiographic Assessment of Epicardial Pacing After Cardiopulmonary Bypass.

Condition:   Disorder of Pacing Function
Interventions:   Device: Right ventricular epicardial pacing;   Procedure: cardiac surgery;   Device: 3D TEE;   Device: Pacemaker lead
Sponsor:   Suzanne Flier, MD
Not yet recruiting - verified July 2016

Gait Pattern Analysis and Feasibility of Gait Training With a Walking Assist Robot in Stroke Patients and Elderly Adults

Conditions:   Stroke;   Healthy
Interventions:   Device: gait rehabilitation with Samsung Hip Assist v1;   Other: gait rehabilitation without Samsung Hip Assist v1
Sponsors:   Samsung Medical Center;   Samsung Electronics
Recruiting - verified July 2016

Efficacy and Safety of Neu2000KWL in Treating Acute Ischemic Stroke Receiving Endovascular Therapy (ENIS I)

Condition:   Ischemic Stroke
Interventions:   Drug: Neu2000KWL High-does group;   Drug: Neu2000KWL Low-does group;   Drug: Placebo
Sponsor:   GNT Pharma
Not yet recruiting - verified July 2016

Trial of Oral Glutamine on Mitochondrial Function in CKD

Conditions:   Cardiovascular Disease;   Sarcopenia;   Endothelial Dysfunction;   Muscle Mitochondrial Function;   Kidney Disease
Interventions:   Dietary Supplement: L-glutamine;   Dietary Supplement: Maltodextrin
Sponsors:   University of Washington;   New York Medical College;   Emory University;   Vanderbilt University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified July 2016

Safety and Efficacy of Two Doses of SP-8203 in Patients With Ischemic Stroke Requiring rtPA

Condition:   Ischemic Stroke
Interventions:   Drug: SP-8203 High dose;   Drug: SP-8203 Low dose;   Drug: Placebo
Sponsor:   Shin Poong Pharmaceutical Co. Ltd.
Recruiting - verified March 2016

Multifocal Brain Magnetic Stimulation in Chronic Ischemic Stroke

Condition:   Stroke
Intervention:   Device: Transcranial magnetic stimulation
Sponsor:   The Methodist Hospital System
Enrolling by invitation - verified July 2016

Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Interventions:   Drug: natalizumab;   Drug: Placebo
Sponsor:   Biogen
Recruiting - verified July 2016

Non-invasive Quantification of Muscle and Liver Glutathione GSH-MRS

Conditions:   Assay Muscle;   Liver Glutathione in Healthy Human
Interventions:   Device: Proton magnetic resonance spectroscopy (1H MRS);   Other: a protein rich breakfast at home;   Other: a protein rich lunch at the Clinical Investigation Center
Sponsors:   University Hospital, Clermont-Ferrand;   UMR 1019 Unité de Nutrition Humaine;   Laboratoire Régional de Nutrition Humaine
Completed - verified July 2016

Dynamic Neuroimaging Biomarkers in Huntington's Disease

Condition:   Brain Neuroimaging Biomarkers in Huntington Disease
Sponsors:   Assistance Publique - Hôpitaux de Paris;   CEA
Recruiting - verified July 2016

A Double-Blinded Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986020 Versus Placebo in Diffuse Cutaneous Systemic Sclerosis (dcSSc)

Condition:   Scleroderma
Interventions:   Drug: BMS-986020;   Other: Placebo
Sponsor:   Bristol-Myers Squibb
Withdrawn - verified July 2016

A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis

Condition:   Scleroderma, Systemic
Interventions:   Drug: Nintedanib;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Validation of HepaFat-Scan for Noninvasive Measurement of Steatosis in Youth

Condition:   Non-alcoholic Fatty Liver Disease
Intervention:   Procedure: Magnetic Resonance Imaging (MRI)
Sponsors:   Emory University;   Resonance Health
Recruiting - verified July 2016

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

Condition:   Chronic Ischemic Stroke
Interventions:   Biological: SB623 Implant (2.5M);   Biological: SB623 Implant (5.0M);   Procedure: Sham surgery
Sponsors:   SanBio, Inc.;   Sunovion
Recruiting - verified June 2016

CardiAMP™ Heart Failure Trial

Condition:   Heart Failure
Interventions:   Biological: Autologous cell therapy;   Device: CardiAMP cell therapy;   Other: Sham
Sponsor:   BioCardia, Inc.
Not yet recruiting - verified July 2016

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

Conditions:   Diffuse Intrinsic Pontine Glioma;   Malignant Glioma;   Recurrent Childhood Brain Neoplasm
Interventions:   Procedure: Diffusion Tensor Imaging;   Procedure: Diffusion Weighted Imaging;   Procedure: Dynamic Contrast-Enhanced Magnetic Resonance Imaging;   Procedure: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging;   Other: Laboratory Biomarker Analysis;   Procedure: Magnetic Resonance Spectroscopic Imaging;   Biological: Pembrolizumab;   Procedure: Perfusion Magnetic Resonance Imaging
Sponsor:   National Cancer Institute (NCI)
Suspended - verified July 2016

Evaluation of the Safety and Potential Therapeutic Effects After Intravenous Transplantation of Cordstem-ST in Patients With Cerebral Infarction

Condition:   Cerebral Infarction
Interventions:   Biological: Cordstem-ST;   Biological: Placebo
Sponsor:   CHABiotech CO., Ltd
Recruiting - verified July 2016

Decompressive Hemicraniectomy in Intracerebral Hemorrhage

Condition:   Cerebral Hemorrhage
Interventions:   Procedure: Decompressive craniectomy (DC) and best medical treatment;   Procedure: Best medical treatment
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified May 2016

Hypnosis to Improve Sleep In Menopause

Condition:   Sleep
Intervention:   Other: Hypnosis
Sponsor:   Baylor University
Recruiting - verified July 2016

Clinical Biomarkers in Alpha-mannosidosis

Condition:   Alpha-Mannosidosis
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified July 2016

Study to Determine if Enhancing Glutamate Transporter Function Produces Antidepressant Effects in People With Major Depressive Disorder

Condition:   Depression
Interventions:   Drug: Diazoxide;   Drug: Placebo
Sponsor:   National Institute of Mental Health (NIMH)
Terminated - verified July 2016

Magnetic Resonance Spectroscopy in Autonomic Failure

Conditions:   Pure Autonomic Failure;   Multiple System Atrophy
Intervention:   Procedure: Magnetic Resonance Spectroscopy Imaging
Sponsor:   Vanderbilt University
Recruiting - verified July 2016

Early Percutaneous Mitral Intervention in Asymptomatic Moderate Mitral Stenosis

Condition:   Moderate Mitral Stenosis
Intervention:   Procedure: Percutaneous Mitral Commissurotomy
Sponsor:   Asan Medical Center
Active, not recruiting - verified July 2016

Treatment Resistant Geriatric Depression in Primary Care

Condition:   Major Depressive Disorder
Intervention:   Drug: Memantine
Sponsors:   Mclean Hospital;   Cambridge Health Alliance;   Harvard University
Active, not recruiting - verified July 2016

The Canadian UnRuptured Endovascular Versus Surgery Trial (CURES)

Condition:   Intracranial Aneurysms
Interventions:   Procedure: Surgical management;   Procedure: Endovascular management
Sponsors:   Centre hospitalier de l'Université de Montréal (CHUM);   Canadian Institutes of Health Research (CIHR);   Centre de Recherche du Centre Hospitalier de l'Université de Montréal;   University of Alberta
Recruiting - verified July 2016

Magnetic Resonance (MR) Spectroscopy in Localized Prostate Cancer

Condition:   Prostate Cancer
Intervention:   Procedure: 3T MR Spectroscopy
Sponsor:   AHS Cancer Control Alberta
Completed - verified June 2014

Identification of Clinically Occult Glioma Cells and Characterization of Glioma Behavior Through Machine Learning Analysis of Advanced Imaging Technology

Condition:   Glioma
Interventions:   Procedure: MRS Imaging;   Procedure: PET Scanning;   Procedure: Diffusion Tensor Imaging
Sponsor:   AHS Cancer Control Alberta
Active, not recruiting - verified July 2016