Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Intravenous Immunoglobulin for Acute Intracranial Hemorrhage

Condition:   Intracranial Hemorrhage, Hypertensive
Interventions:   Drug: Immunoglobulin Therapy;   Other: Standard management
Sponsor:   Wei Wang
Not yet recruiting - verified May 2016

Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients

Condition:   Ischemic Stroke
Interventions:   Procedure: remote ischemic postconditioning;   Procedure: sham remote ischemic postconditioning
Sponsor:   Guangzhou University of Traditional Chinese Medicine
Recruiting - verified May 2016

INSIGHT, A Comprehensive, Multidisciplinary Brain Training System

Condition:   Cognitive Ability, General
Interventions:   Behavioral: Cognitive Training - 48 sessions;   Behavioral: Fitness;   Behavioral: Active Control;   Device: active tDCS;   Device: sham tDCS;   Behavioral: Cognitive Training - 20 sessions
Sponsors:   University of Illinois at Urbana-Champaign;   The City College of New York;   Aptima, Inc.;   Georgia Institute of Technology;   Circinnus LLC;   Autonomous University of Madrid, Spain
Completed - verified May 2016

A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes

Condition:   Ischemic Stroke
Intervention:   Drug: TF0023
Sponsor:   Techfields Inc
Not yet recruiting - verified May 2016

Impact of Forced Expiration On Pleural Drainage Duration (KPDP)

Conditions:   Pulmonary Malformations;   Child
Intervention:   Procedure: Forced expiration
Sponsor:   University Hospital, Tours
Recruiting - verified May 2016

Targeted Temperature Management After In-Hospital Cardiac Arrest

Condition:   Hypoxic Ischemic Encephalopathy
Interventions:   Device: Arctic Sun®;   Device: Arcticgel™;   Procedure: Conventional antipyretic treatment
Sponsor:   Asan Medical Center
Recruiting - verified May 2016

A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis

Condition:   Scleroderma, Systemic
Interventions:   Drug: Nintedanib;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2016

Neuroimaging Study of Risk Factors for Adolescent Bipolar Disorder

Condition:   Attention Deficit Hyperactivity Disorder
Interventions:   Drug: mixed amphetamine salts-extended release (MAS-XR);   Drug: Placebo
Sponsors:   University of Cincinnati;   National Institute of Mental Health (NIMH)
Recruiting - verified June 2015

Mitral Implantation of TRAnscatheter vaLves

Condition:   Mitral Valve Disease
Intervention:   Device: Transcatheter Mitral Valve Replacement
Sponsors:   Mayra Guerrero;   Henry Ford Hospital
Recruiting - verified May 2016

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

Conditions:   Diffuse Intrinsic Pontine Glioma;   Malignant Glioma;   Recurrent Childhood Brain Neoplasm
Interventions:   Procedure: Diffusion Tensor Imaging;   Procedure: Diffusion Weighted Imaging;   Procedure: Dynamic Contrast-Enhanced Magnetic Resonance Imaging;   Procedure: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging;   Other: Laboratory Biomarker Analysis;   Procedure: Magnetic Resonance Spectroscopic Imaging;   Biological: Pembrolizumab;   Procedure: Perfusion Magnetic Resonance Imaging
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified May 2016

Evaluating Therapeutic Response to Novo-TTF

Condition:   Glioblastoma Multiforme
Intervention:   Device: Novo-TTF
Sponsor:   University of Pennsylvania
Recruiting - verified May 2016

12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II Depression

Condition:   Bipolar Depression
Interventions:   Drug: Infliximab;   Other: Saline
Sponsors:   University Health Network, Toronto;   Clinical Investigation Centre for Innovative Technology Network;   Stanford University
Recruiting - verified May 2016

Metabolic Anomolies Associated With the 6 Month Clinical Evolution of Patients Suffering From Motor Conversion Disorder

Condition:   Conversion Disorder
Intervention:   Device: PET CT 18 FDG
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Recruiting - verified February 2016

Early Feasibility Study of the Tendyne Mitral Valve System

Condition:   Mitral Valve Regurgitation
Intervention:   Device: Tendyne Mitral Valve System
Sponsor:   Tendyne Holdings, LLC
Recruiting - verified May 2016

ATP in Alzheimer Disease

Condition:   Alzheimer's Disease
Interventions:   Drug: ADENOSINE TRIPHOSPHATE;   Drug: PLACEBO
Sponsor:   Sara Varea
Active, not recruiting - verified May 2016

Decompressive Hemicraniectomy in Intracerebral Hemorrhage

Condition:   Cerebral Hemorrhage
Interventions:   Procedure: Decompressive craniectomy (DC) and best medical treatment;   Procedure: Best medical treatment
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified May 2016

Repetitive Transcranial Magnetic Stimulation Equipment Testing and Pilot Study

Condition:   Healthy Volunteer
Intervention:   Device: TMS
Sponsor:   National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2016

Sedation vs. Intubation for Endovascular Stroke TreAtment

Condition:   Acute Ischemic Stroke
Intervention:   Procedure: Endovascular recanalisation
Sponsor:   University Hospital Heidelberg
Completed - verified May 2016

Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Canagliflozin, 100 mg;   Drug: Canagliflozin, 300 mg;   Drug: Placebo
Sponsor:   Janssen Research & Development, LLC
Recruiting - verified May 2016

A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome

Condition:   Li-Fraumeni Syndrome
Intervention:   Drug: Metformin
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified March 2016

CLOTBUST Hands-Free: A Phase I/II Pilot Safety Trial

Condition:   Stroke
Interventions:   Device: 2-MHz transcranial Doppler ultrasound;   Device: 2-MHz transcranial Doppler ultrasound insonation
Sponsors:   The University of Texas Health Science Center, Houston;   University of Alabama at Birmingham
Completed - verified May 2016

EASE MITRAL Expertise-based Assessment Study on Clinical Efficacy of Profile 3D in MITRAL Valve Annuloplasty

Condition:   Mitral Valve Insufficiency
Intervention:  
Sponsor:   Medtronic Bakken Research Center
Active, not recruiting - verified May 2016

Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis

Conditions:   Systemic Sclerosis;   Scleroderma
Intervention:   Drug: Ambrisentan
Sponsors:   University of Pennsylvania;   Gilead Sciences
Active, not recruiting - verified May 2016

Multimodal Neuroimaging of Treatment Effects in Adolescent Mania

Conditions:   Mania;   Bipolar Disorder
Interventions:   Drug: Quetiapine & Placebo;   Drug: Lithium and Placebo;   Other: Healthy Controls
Sponsors:   University of Cincinnati;   Children's Hospital Medical Center, Cincinnati
Completed - verified May 2015

A Comparison of Hemorrhagic and Ischemic Strokes Among Blacks and Whites

Conditions:   Ischemic Stroke;   TIA;   Hemorrhage
Intervention:  
Sponsors:   University of Cincinnati;   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified May 2016

Pharmacokinetics and Tolerability of Zavesca® (Miglustat) In Patients With Juvenile GM2 Gangliosidosis

Condition:   Gangliosidoses GM2
Intervention:   Drug: miglustat
Sponsors:   The Hospital for Sick Children;   Actelion
Completed - verified May 2016

An fMRI Study of Self-regulation in Adolescents With Bulimia Nervosa

Condition:   Eating Disorders
Interventions:   Other: MRI;   Behavioral: Neuropsychological Testing
Sponsors:   New York State Psychiatric Institute;   National Institute of Mental Health (NIMH)
Active, not recruiting - verified May 2016

Scleroderma: Cyclophosphamide or Transplantation (SCOT)

Conditions:   Scleroderma, Systemic;   Sclerosis;   Autoimmune Disease
Interventions:   Procedure: Autologous stem cell transplantation;   Drug: Cyclophosphamide;   Drug: Antithymocyte globulin, equine;   Drug: Methylprednisolone;   Drug: Growth colony stimulating factor (G-CSF);   Radiation: Total body irradiation (TBI)
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed - verified May 2016