Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Magnetic Resonance Spectroscopy (MRS) in Midlife Depression

Conditions:   Depression;   Bipolar-current Episode Depression
Sponsor:   Emory University
Not yet recruiting - verified September 2015

Autologous Bone Marrow Mesenchymal Stem Cell Transplantation for Chronic Ischemic Stroke

Condition:   Stroke
Intervention:   Genetic: Intravenous stem cell transplantation
Sponsors:   Southern Medical University, China;   Second Affiliated Hospital of Guangzhou Medical University
Recruiting - verified September 2015

ARCH II Study (Alcohol Research Center on HIV Study II)

Conditions:   Alcohol Consumption;   HIV;   Motivation
Interventions:   Behavioral: Motivational Interviewing;   Other: Questionnaire assessment;   Other: Neurocognitive assessments;   Other: Blood specimens
Sponsors:   University of Florida;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified September 2015

Real-time fMRI for the Treatment of Aggressive Behavior in Adolescents

Conditions:   Aggression;   Conduct Disorder
Interventions:   Behavioral: Real-time fMRI feedback;   Behavioral: Treatment as usual
Sponsors:   Central Institute of Mental Health, Mannheim;   Radboud University
Not yet recruiting - verified June 2015

ADAPT Trial: a Direct Aspiration First Pass Technique

Condition:   Ischemic Cerebrovascular Accident
Intervention:   Other: Adapt/Standard Stent Retriever (SR) Group
Sponsors:   Medical University of South Carolina;   Icahn School of Medicine at Mount Sinai
Recruiting - verified September 2015

Dairy Intake and Brain Health in Aging

Condition:   Aged Healthy Volunteer
Sponsors:   University of Kansas Medical Center;   National Dairy Council
Active, not recruiting - verified September 2015

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)

Condition:   Brain Ischemia
Interventions:   Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
Sponsor:   Genentech, Inc.
Recruiting - verified October 2015

PERIGON Pivotal Trial

Condition:   Aortic Valve Replacement
Intervention:   Device: Model 400 aortic valve bioprosthesis
Sponsors:   Medtronic Cardiovascular;   Medtronic
Recruiting - verified August 2015

Mitralign Percutaneous Annuloplasty First in Man Study

Condition:   Functional Mitral Regurgitation
Intervention:   Device: MPAS Implant
Sponsors:   Mitralign, Inc.;   Medstar Research Institute;   The Cooper Health System;   Cardiovascular Research Center
Completed - verified April 2014

POSITIVE Stroke Clinical Trial

Condition:   Ischemic Stroke
Intervention:   Device: Endovascular Mechanical Thrombectomy
Sponsors:   Medical University of South Carolina;   Vanderbilt University
Recruiting - verified September 2015

NMDA Antagonists in Bipolar Depression

Condition:   Bipolar Disorder
Interventions:   Drug: Standard of Care;   Drug: Ketamine;   Drug: D-cycloserine
Sponsor:   New York State Psychiatric Institute
Active, not recruiting - verified September 2015

Mitralign Percutaneous Annuloplasty System for Chronic Functional Mitral Valve Regurgitation

Condition:   Mitral Valve Regurgitation
Intervention:   Device: percutaneous annuloplasty
Sponsor:   Mitralign, Inc.
Recruiting - verified October 2015

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: aleglitazar;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified October 2015

Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia

Condition:   Cardiac Arrest
Interventions:   Drug: amiodarone;   Drug: Lidocaine;   Other: Normal saline
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research  (CIHR);   Heart and Stroke Foundation of Canada;   American Heart Association;   Defence Research and Development Canada;   U.S. Army Medical Research and Materiel Command
Recruiting - verified October 2015

A Study of RO5093151 in Patients With Non-Alcoholic Fatty Liver Disease

Condition:   Fatty Liver, Non-alcoholic Fatty Liver Disease, NAFLD
Interventions:   Drug: Placebo;   Drug: RO5093151
Sponsor:   Hoffmann-La Roche
Completed - verified October 2015

Vagus Nerve Stimulation Clinical Outcomes Measured Prospectively in Patients Stimulated

Condition:   Epilepsy
Sponsor:   Cyberonics, Inc.
Recruiting - verified September 2015

Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-II)

Condition:   Intracerebral Hemorrhage
Intervention:   Drug: Nicardipine hydrochloride
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Institute of Neurological Disorders and Stroke (NINDS);   Medical University of South Carolina;   Johns Hopkins University;   University of Michigan
Suspended - verified October 2015

Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions:   Procedure: Mitral Valve Repair;   Procedure: CABG
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research  (CIHR);   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified October 2015

MRI to Measure Liver Fat Content

Conditions:   Fatty Liver;   Hepatitis
Intervention:   Procedure: Diagnostic Radiology: 1H-MRS of the liver
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed - verified June 2011

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