Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Comparison Between Hand-acupuncture and Electro-acupuncture Stimulation in the Treatment of Menopause

Conditions:   Menopause;   Puncture Site Reaction
Interventions:   Behavioral: Hand-acupuncture;   Device: Electrico-acupuncture
Sponsors:   The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine;   The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
Recruiting - verified March 2014

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)

Condition:   Brain Ischemia
Interventions:   Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
Sponsor:   Genentech
Recruiting - verified April 2014

Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Canagliflozin, 100 mg;   Drug: Canagliflozin, 300 mg;   Drug: Placebo
Sponsor:   Janssen Research & Development, LLC
Not yet recruiting - verified April 2014

Proton MR Spectroscopy and 18F-Fluorocholine PET for Breast Cancer Diagnosis

Conditions:   Breast Cancer Diagnosis;   Positron Emission Tomography;   Magnetic Resonance Imaging
Interventions:   Drug: 18F-FCH;   Drug: Magnevist
Sponsor:   National Taiwan University Hospital
Recruiting - verified April 2014

Blood Pressure Variability in Acute Ischemic Stroke

Condition:   Acute Ischemic Stroke
Intervention:  
Sponsors:   Aristotle University Of Thessaloniki;   A&D Company Limited
Recruiting - verified December 2013

Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma

Condition:   Malignant Pleural Mesothelioma
Interventions:   Drug: defactinib (VS-6063);   Drug: Placebo
Sponsor:   Verastem, Inc.
Recruiting - verified April 2014

Treatment for Non-Alcoholic Fatty Liver With Different Doses of Vitamin E

Condition:   Fatty Liver
Interventions:   Dietary Supplement: Vitamin E 200 IU/d;   Dietary Supplement: Vitamin E 400 IU/d;   Dietary Supplement: Vitamin E 800 IU/d;   Behavioral: Diet and Exercise
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified March 2014

Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD

Condition:   Obsessive Compulsive Disorder
Interventions:   Drug: Minocycline;   Other: Placebo
Sponsors:   New York State Psychiatric Institute;   National Institute of Mental Health (NIMH);   Weill Medical College of Cornell University
Recruiting - verified April 2014

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: aleglitazar;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

Clinical Outcome Study for Dysferlinopathy

Conditions:   Dysferlinopathy;   LGMD2B;   Miyoshi Myopathy
Intervention:  
Sponsors:   Newcastle-upon-Tyne Hospitals NHS Trust;   Jain Foundation (Grant sponsor)
Active, not recruiting - verified October 2012

DaTSCAN Imaging in Aging and Neurodegenerative Disease

Conditions:   Dementia;   Parkinsonism;   Mild Cognitive Impairment;   REM Sleep Behavior Disorder
Interventions:   Drug: I-123 Ioflupane solution injection prior to SPECT scan (DaTscan);   Device: Single photon emission computed tomography (SPECT) scan
Sponsor:   Mayo Clinic
Enrolling by invitation - verified April 2014

Physical Fitness, Cardiovascular and Brain Health

Condition:   Hypertension
Interventions:   Behavioral: Aerobic Exercise;   Behavioral: Relaxation
Sponsors:   University of Texas at Austin;   American Federation for Aging Research
Completed - verified April 2014

A Study of RO5093151 in Patients With Non-Alcoholic Fatty Liver Disease

Condition:   Fatty Liver, Non-alcoholic Fatty Liver Disease, NAFLD
Interventions:   Drug: RO5093151;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

A Clinical Trial of Exendin-4 for the Treatment of Alzheimer's Disease

Condition:   Alzheimer's Disease
Intervention:   Drug: Exendin-4 (Exenatide)
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute on Aging (NIA)
Recruiting - verified August 2013

Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions:   Procedure: Mitral Valve Repair;   Procedure: CABG
Sponsors:   Mount Sinai School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified April 2014

Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions:   Procedure: Mitral Valve Repair with Annuloplasty;   Procedure: Mitral Valve Replacement
Sponsors:   Mount Sinai School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified April 2014

Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome--Pediatric Heart Network

Condition:   Marfan Syndrome
Interventions:   Drug: Losartan Potassium;   Drug: Atenolol
Sponsors:   New England Research Institutes;   National Heart, Lung, and Blood Institute (NHLBI);   FDA Office of Orphan Products Development;   National Marfan Foundation
Completed - verified January 2014

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