Metabolic Syndrome

Clinical Trial Finder

Many patients with metabolic syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Effects of Bariatric Surgery on Inspiratory Metaboreflex in Obese Subjects

Conditions:   Obesity;   Metabolic Syndrome
Interventions:   Other: Bariatric surgery;   Other: Control
Sponsor:   University of Cruz Alta
Recruiting - verified February 2017

Personalized Nutrition Prediction for Metabolic Syndrome Patients, an Open Single-center Study

Condition:   Metabolic Syndrome
Intervention:   Other: Personalized recommendations for diet
Sponsor:   Galilee CBR
Not yet recruiting - verified February 2017

Intravenous Infusion of Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Bone Marrow (BM) Derived MSCs to Evaluate Cytokine Suppression in Patients With Chronic Inflammation Due to Metabolic Syndrome.

Conditions:   Endothelial Dysfunction;   Metabolic Syndrome;   Chronic Inflammation
Interventions:   Biological: UCMSCs;   Biological: BMMSCs;   Other: Placebo
Sponsor:   Joshua M Hare
Not yet recruiting - verified February 2017

Characterization of Metabolic and Brain Effects of Rising Glucagon During an Oral Glucose Challenge

Conditions:   Metabolic Syndrome;   Diabetes
Interventions:   Drug: Intravenous glucagon;   Drug: Intravenous saline
Sponsor:   University Hospital Tuebingen
Recruiting - verified February 2017

Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

Condition:   Obstructive Sleep Apnea
Sponsor:   Milton S. Hershey Medical Center
Enrolling by invitation - verified February 2017

Investigation of Predictive Indices to Objectively Guide Choice of CPAP Interface

Condition:   Obstructive Sleep Apnea of Adult
Intervention:   Device: CPAP interfaces
Sponsor:   Singapore General Hospital
Active, not recruiting - verified February 2017

The Cleveland Cardiometabolic Cohort

Conditions:   HIV;   Lipodystrophy
Sponsor:   Grace McComsey
Recruiting - verified February 2017

Effects of Short-term Interventions for a Healthy Lifestyle on the Human Lipidome in Subjects With Metabolic Syndrome

Conditions:   Metabolic Syndrome;   NAFLD;   Obesity;   Hypertension
Interventions:   Behavioral: Lifestyle intervention (physical activity);   Dietary Supplement: Lifestyle intervention (PUFA/isomaltulose-enriched muffin)
Sponsor:   German Institute of Human Nutrition
Recruiting - verified February 2017

Evaluation of 3-V Bioscience-2640 to Reduce de Novo Lipogenesis in Subjects With Characteristics of Metabolic Syndrome

Condition:   Metabolic Syndrome
Intervention:   Drug: 3-V Bioscience-2640
Sponsors:   University of Missouri-Columbia;   3V Biosciences, Inc.
Recruiting - verified October 2016

Body Fat Mass Association With Clinical Metabolic Profiles, Markers of Inflammation and Adipocytokines

Condition:   Overweight and Obesity
Sponsor:   Tungs’ Taichung Metroharbour Hospital
Completed - verified February 2017

A Short Term Evaluation of a Structured Weight Loss Plan in Overweight and Obese Adults

Condition:   Metabolic Syndrome
Interventions:   Other: "Grab-and-Go" meal plan;   Other: "Jump-Start" meal plan
Sponsors:   University of Missouri-Columbia;   Robert C. Atkins Foundation
Active, not recruiting - verified August 2016

Assessment of the Prevalence of Small Fiber Peripheral Neuropathy Among Non-diabetic Obese Patients

Condition:   Neuropathology
Intervention:   Device: Exams
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Recruiting - verified May 2016

Breast Cancer WEight Loss Study (BWEL Study)

Condition:   Breast Carcinoma
Interventions:   Other: Health Education Program;   Other: Weight Loss Intervention
Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI);   Division of Cancer Control;   NIH Biomarker, Imaging and Quality of Life Studies Funding Program (BIQSFP)
Recruiting - verified February 2017

FGF21 and Fructose Challenge in Humans

Condition:   Fasting
Intervention:   Dietary Supplement: oral carbohydrate challenge
Sponsor:   Beth Israel Deaconess Medical Center
Recruiting - verified February 2017

Retroperitoneal Lymph Node Dissection in Treating Patients With Stage I-IIA Testicular Seminoma

Conditions:   Lymphadenopathy;   Stage I Testicular Seminoma;   Stage II Testicular Seminoma
Interventions:   Other: Laboratory Biomarker Analysis;   Procedure: Retroperitoneal Lymph Node Dissection
Sponsors:   University of Southern California;   National Cancer Institute (NCI)
Recruiting - verified February 2017

Study of the Reversibility of Glucose Intolerance Caused by Chronic Aspartame Consumption

Condition:   Glucose Metabolism Disorder
Interventions:   Other: Oral glucose tolerance test (OGTT);   Other: Diet soda containing aspartame only
Sponsor:   Rockefeller University
Recruiting - verified February 2017

Phlebotomy and Polycystic Ovary Syndrome

Conditions:   Hyperandrogenism;   Metabolic Cardiovascular Syndrome
Interventions:   Procedure: Phlebotomy;   Drug: ethinylestradiol;   Drug: Cyproterone Acetate
Sponsors:   Manuel Luque Ramírez;   Instituto de Salud Carlos III
Recruiting - verified February 2017

Canola Oil Multi-center Intervention Trial II

Conditions:   Cardiovascular Disease;   Metabolic Syndrome
Interventions:   Other: Canola Oil;   Other: High oleic acid canola oil;   Other: Western diet oil combination
Sponsors:   Penn State University;   Canola Council of Canada;   University of Manitoba;   Laval University;   St. Michael's Hospital, Toronto;   St. Boniface General Hospital Research Centre
Completed - verified February 2017

Interval Training, Inflammation and Immune Function

Conditions:   Aging;   Disease
Intervention:   Behavioral: High Intensity Interval training
Sponsor:   Duke University
Active, not recruiting - verified February 2017

A Multi-Center Study of the CF Quantum® Sweat Test System

Condition:   Cystic Fibrosis
Intervention:   Device: Iontophoresis sweat test
Sponsor:   Polychrome Medical, Inc.
Recruiting - verified February 2017

Optimizing Individual Nutrition in Preterm Very Low Birth Weight Infants

Conditions:   Infant, Premature, Diseases;   Infant, Small for Gestational Age
Interventions:   Dietary Supplement: Individualized Nutrition;   Dietary Supplement: Optimized nutrition
Sponsors:   University of Texas Southwestern Medical Center;   Children's Medical Center Dallas;   The Gerber Foundation
Recruiting - verified February 2017

Galantamine Effects in Patients With Metabolic Syndrome

Condition:   Abdominal Obesity Metabolic Syndrome
Interventions:   Drug: Galantamine;   Drug: Placebo (for galantamine)
Sponsors:   University of Sao Paulo;   University of Nove de Julho;   Feinstein Institute for Medical Research
Completed - verified February 2017

Exercise Intervention Metabolic Syndrome Prostate Cancer Black Men

Conditions:   Physical Activity;   Metabolic Syndrome;   Prostate Cancer
Interventions:   Behavioral: Exercise;   Behavioral: Attention Control
Sponsor:   Georgetown University
Completed - verified September 2014

Impact of a Nutritional Supplement on Metabolic Health

Condition:   Cardiovascular Disease Prevention
Intervention:   Other: Nutrition bar
Sponsors:   Children's Hospital & Research Center Oakland;   USDA Beltsville Human Nutrition Research Center
Recruiting - verified February 2017

Research Aimed at Improving Both Mood and Weight

Conditions:   Depression;   Obesity
Intervention:   Behavioral: RAINBOW Intervention Program
Sponsors:   Palo Alto Medical Foundation;   National Heart, Lung, and Blood Institute (NHLBI);   University of Washington;   University of Pittsburgh;   Stanford University;   University of Illinois at Chicago
Active, not recruiting - verified February 2017

Stress and Sugar Synergy

Conditions:   Metabolic Syndrome;   Insulin Resistance;   Dyslipidemia
Interventions:   Other: orange juice;   Other: sucrose
Sponsors:   University of California, Davis;   University of California, San Francisco;   USDA, Western Human Nutrition Research Center
Recruiting - verified December 2016

An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer

Conditions:   Metabolic Syndrome;   Obesity
Interventions:   Behavioral: Facility-based Exercise;   Behavioral: Home-based Exercise
Sponsor:   Georgetown University
Active, not recruiting - verified February 2017

Canola Oil, Fibre and DHA Enhanced Clinical Trial

Condition:   Metabolic Syndrome
Interventions:   Dietary Supplement: Butter, sunflower and safflower oil;   Dietary Supplement: High Oleic Canola Oil and DHA (HOCO-DHA);   Dietary Supplement: Barley beta-glucan;   Dietary Supplement: HOCO-DHA and Barley beta-glucan
Sponsors:   University of Manitoba;   Canadian Institutes of Health Research (CIHR);   Agriculture and Agri-Food Canada
Completed - verified February 2017

Effect of Blueberry Consumption on Metabolic Syndrome & DNA Damage

Conditions:   Metabolic Syndrome;   Insulin Resistance;   DNA Damage
Interventions:   Dietary Supplement: Blueberry Powder;   Dietary Supplement: Placebo
Sponsors:   Children's Hospital & Research Center Oakland;   U.S. Highbush Blueberry Council;   USDA Agricultural Research Station in Albany, CA
Enrolling by invitation - verified February 2017

Utilizing a Promotora Model for Rural Adult Hispanics Diagnosed With Metabolic Syndrome: A Clinical Trial

Condition:   Metabolic Syndrome
Intervention:   Behavioral: Promotora plus standard physical screening exam , hemoglobin A1c levels, lipid panels, fasting glucose, height, weight, BMI, Complete Blood Count
Sponsors:   Family Medicine Residency of Idaho;   Mountain States Group;   Saint Alphonsus Medical Group;   Quantified, Inc.
Withdrawn - verified February 2017

Regulating Efficacy and Wellness in Diabetes

Conditions:   Diabetes Type 2;   Metabolic Syndrome
Intervention:   Behavioral: Walking exercise
Sponsors:   University of Illinois at Urbana-Champaign;   National Institute on Aging (NIA)
Completed - verified February 2017

Relationship Between Gestational Diabetes and Type 2 Diabetes

Conditions:   Gestational Diabetes;   Type 2 Diabetes
Sponsor:   Laval University
Active, not recruiting - verified February 2017

Effect of Exercise Before Gastric Bypass

Condition:   Morbid Obesity
Intervention:   Behavioral: High intensity exercise
Sponsor:   Norwegian University of Science and Technology
Completed - verified February 2017

Abundance and Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease (NAFLD)

Condition:   Nonalcoholic Fatty Liver Disease
Sponsor:   Vanderbilt University
Enrolling by invitation - verified February 2017

Effects of High-fat and Low-fat Diet on the Gut

Condition:   Metabolic Syndrome X
Interventions:   Dietary Supplement: high fat diet followed by low fat diet;   Dietary Supplement: low fat diet followed by high fat diet
Sponsor:   Maastricht University Medical Center
Completed - verified December 2008

Effect of Valsartan on Lipid Subfractions in Hypertensive Patients With Metabolic Syndrome

Conditions:   Hypertension;   Metabolic Syndrome
Intervention:   Drug: Valsartan
Sponsor:   Novartis
Completed - verified February 2017

Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic Syndrome

Condition:   Dyslipidemia
Interventions:   Drug: Fluvastatin extended release, fenofibrate;   Drug: Fixed combination simvastatin/ezetimibe
Sponsor:   Novartis
Completed - verified February 2017

Other Effects of Fluvastatin Are Investigated in Patients With Metabolic Syndrome

Condition:   Metabolic Syndrome
Intervention:   Drug: Fluvastatin
Sponsor:   Novartis
Completed - verified February 2017