Metabolic Syndrome

Clinical Trial Finder

Many patients with metabolic syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

CCK1R Function in Patient Leukocytes

Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Metabolic Syndrome
Sponsor:   Mayo Clinic
Completed - verified April 2017

Periodized Aerobic Interval Training in Metabolic Syndrome

Conditions:   Metabolic Syndrome;   Metabolic Syndrome X
Intervention:   Behavioral: Periodized aerobic interval training
Sponsor:   Universidade Estadual Paulista Júlio de Mesquita Filho
Completed - verified April 2017

The Role of Sleeve Gastrectomy in Dyslpidemia

Condition:   Obesity
Sponsor:   Assiut University
Not yet recruiting - verified April 2017

Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk

Conditions:   Osteoporosis;   Metabolic Syndrome;   Spinal Cord Injuries
Interventions:   Drug: Rosuvastatin Calcium;   Drug: Placebo Oral Tablet;   Dietary Supplement: Coenzyme Q10;   Dietary Supplement: Calcium Carbonate;   Dietary Supplement: Vitamin D
Sponsors:   Dr. B. Catharine. Craven;   The Craig H. Neilsen Foundation;   Toronto Rehabilitation Institute;   University Health Network, Toronto;   University of Miami
Not yet recruiting - verified April 2017

Randomised Placebo-controlled Study of FMT to Impact Body Weight and Glycemic Control in Obese Subjects With T2DM

Conditions:   Type2 Diabetes;   Type 2 Diabetes Mellitus;   Obese
Interventions:   Procedure: Fecal Microbiota Transplantation;   Behavioral: Lifestyle Modification Program;   Procedure: Sham
Sponsor:   Chinese University of Hong Kong
Recruiting - verified April 2017

Study: Diet and Exercise Study to Improve Brain Blood Flow: Blood Flow Improvement Trial

Condition:   PreDiabetes
Intervention:   Behavioral: Diet and Exercise
Sponsor:   University of Wisconsin, Madison
Recruiting - verified April 2017

The Effect of Sitting and Moderate Exercise on Plasma Triglyceride Elevation After a Meal

Conditions:   Atherosclerosis;   Metabolic Syndrome
Interventions:   Behavioral: Prolonged sitting with exercise;   Behavioral: Prolonged sitting without exercise
Sponsor:   University of Texas at Austin
Recruiting - verified April 2017

The Effects of Prolonged Standing Compared to Prolonged Sitting on Postprandial Lipemia

Conditions:   Metabolic Syndrome;   Atherosclerosis
Interventions:   Behavioral: Prolonged Standing;   Behavioral: Prolonged Sitting
Sponsor:   University of Texas at Austin
Not yet recruiting - verified April 2017

Induced and Controlled Dietary Ketosis as a Regulator of Obesity and Metabolic Syndrome Pathologies

Conditions:   Metabolic Syndrome;   Diabetes Mellitus, Type 2;   Pre Diabetes
Intervention:   Behavioral: Dietary Ketosis: Regulator of Obesity and Metabolic Syndrome
Sponsors:   Bristlecone Behavioral Health, Inc.;   University of Minnesota - Clinical and Translational Science Institute
Completed - verified April 2017

Apalutamide Plus Intermittent Hormone Therapy Versus Intermittent Hormone Therapy Alone in Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Apalutamide;   Drug: IHT
Sponsors:   Robert J Amato;   Janssen Scientific Affairs, LLC
Not yet recruiting - verified April 2017

Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism

Conditions:   Overweight;   Obesity;   Dysglycemia;   Prediabetes;   Metabolic Syndrome;   Type 2 Diabetes
Intervention:   Other: fructose, allulose, tagatose, or sorbose
Sponsors:   University of Toronto;   Canadian Diabetes Association;   The Physicians' Services Incorporated Foundation;   Banting & Best Diabetes Centre;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified April 2017

Breast Cancer WEight Loss Study (BWEL Study)

Condition:   Breast Carcinoma
Interventions:   Other: Health Education Program;   Other: Weight Loss Intervention
Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI);   Division of Cancer Control;   NIH Biomarker, Imaging and Quality of Life Studies Funding Program (BIQSFP)
Recruiting - verified April 2017

Study Comparing Fish Oil and Krill Oil

Conditions:   Inflammation;   Dyslipidemia
Interventions:   Dietary Supplement: Fish oil;   Dietary Supplement: Krill oil
Sponsors:   Tufts University;   Prevention Pharmaceuticals
Terminated - verified April 2017

Fish or Nuts? Dietary Effects on Cardiometabolic Risk Factors and Persistent Organic Pollutants

Conditions:   Obesity;   Metabolic Syndrome;   Diabetes
Interventions:   Other: The fatty fish group;   Other: The nut group;   Other: The control group
Sponsor:   Oslo University Hospital
Recruiting - verified April 2017

Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease

Conditions:   Liver Disease;   Fatty Liver
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 31, 2017

Impact of a Nutritional Supplement on Metabolic Health

Condition:   Cardiovascular Disease Prevention
Intervention:   Other: Nutrition bar
Sponsors:   Children's Hospital & Research Center Oakland;   USDA Beltsville Human Nutrition Research Center
Completed - verified February 2017

Effects of Colchicine in Non-Diabetic Adults With Metabolic Syndrome

Conditions:   Obesity;   Metabolic Disease
Interventions:   Drug: Colchicine 0.6 mg given;   Drug: Placebo capsules given
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified February 17, 2017

Magnetic Resonance Imaging-Portfolio Diet Study #7

Conditions:   Cardiovascular Diseases;   Hypercholesterolemia;   Diabetes;   Metabolic Syndrome;   Obesity
Interventions:   Behavioral: Portfolio Plus Diet;   Behavioral: DASH-like (high fibre) dietary advice
Sponsors:   St. Michael's Hospital, Toronto;   Canadian Institutes of Health Research (CIHR);   University of Toronto;   Laval University;   University of Manitoba;   University of British Columbia
Withdrawn - verified April 2017

Metformin in the Diastolic Dysfunction of Metabolic Syndrome

Conditions:   Metabolic Syndrome X;   Diastolic Dysfunction;   Insulin Resistance
Interventions:   Behavioral: Lifestyle Counseling;   Drug: Metformin
Sponsors:   Universidade do Porto;   Centro Hospitalar de Vila Nova de Gaia/Espinho;   Merck Serono International SA
Active, not recruiting - verified April 2017

Role of Growth Hormone Antagonism in Modulating Insulin Sensitivity in Subjects With Pre-diabetes

Conditions:   Diabetes;   Metabolic Syndrome;   Insulin Resistance
Intervention:   Drug: pegvisomant
Sponsors:   University of California, San Francisco;   San Francisco General Hospital
Completed - verified April 2017

The Reus-Tarragona Birth Cohort Study of Early Development and Ageing.

Condition:   Intrauterine Development
Intervention:   Other: Observational
Sponsors:   Institut Investigacio Sanitaria Pere Virgili;   Italfarmaco;   Instituto de Salud Carlos III;   CIBERobn
Recruiting - verified April 2017

Optimal Timing of Physical Activity in Cancer Treatment

Conditions:   Metabolic Syndrome;   Vascular Disorders;   Cardiovascular Risk Factors;   Fatigue
Interventions:   Other: A tailored physical activity program during chemotherapy;   Other: A tailored physical activity program after chemotherapy
Sponsor:   University Medical Center Groningen
Recruiting - verified April 2017

Mifepristone for Metabolic Syndrome

Conditions:   Endocrine Disease;   Diabetes
Intervention:   Drug: Mifepristone
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified December 16, 2016

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

Conditions:   Asthma;   Atherosclerosis;   Metabolic Syndrome;   Insulin Resistance;   Cancer
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Enrolling by invitation - verified December 27, 2016

Glycemic Index - Variability Among Individuals

Conditions:   Diabetes;   Obesity;   Metabolic Syndrome;   Cardiovascular Disease
Interventions:   Other: Carbohydrate + Protein;   Other: Carbohydrate + Fat;   Other: Fiber;   Other: Carbohydrate load
Sponsors:   Tufts University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified April 2017

Bioactive Plant Foods: Effects on Functional Bioavailability and Genomic Stability

Condition:   Metabolic Syndrome
Intervention:   Dietary Supplement: plant based nutrition bar
Sponsors:   Tufts University;   National Academy of Agricultural science, Korea;   Sungkyunkwan University
Completed - verified April 2017

Metabolic Syndrome in Young Patients With Acute Lymphoblastic Leukemia in Remission

Conditions:   Fatigue;   Leukemia;   Long-term Effects Secondary to Cancer Therapy in Children
Interventions:   Other: laboratory biomarker analysis;   Other: metabolic assessment;   Other: questionnaire administration;   Procedure: assessment of therapy complications;   Procedure: fatigue assessment and management;   Procedure: quality-of-life assessment
Sponsors:   Vanderbilt University Medical Center;   National Cancer Institute (NCI)
Completed - verified April 2017

Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

Condition:   Oxidative Stress
Interventions:   Dietary Supplement: angel's plant (Angelica keiskei);   Dietary Supplement: Angel's plant (Angelica keiskei)
Sponsor:   Tufts University
Completed - verified April 2017

Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women

Conditions:   Atherosclerosis;   Diabetes Mellitus;   Obesity;   Dyslipidemia;   Hypertension
Interventions:   Behavioral: Exercise;   Behavioral: Weight Loss
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 18, 2015

Multifactor Risk Reduction for Optimal Management of PAD

Condition:   Peripheral Arterial Disease
Intervention:   Behavioral: exercise
Sponsors:   Palo Alto Veterans Institute for Research;   Stanford University;   University of California, San Francisco
Active, not recruiting - verified April 2017

Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth

Conditions:   Impaired Glucose Tolerance;   Pre-diabetes;   Childhood Obesity;   Insulin Resistance;   Metabolic Syndrome
Sponsors:   Yale University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed - verified April 2017

Evaluation of Albuminuria HIV-Infected Patients

Conditions:   HIV-Associated Focal Segmental Glomerulosclerosis;   HIV-Associated Collapsing Glomerulopathy;   Proteinuria;   Albuminuria;   Renal Tubular Toxicity
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified December 24, 2014

Effect of Increasing Testosterone on Insulin Sensitivity in Men With the Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Drug: Zoladex;   Drug: Testosterone gel;   Drug: Anastrozole Pill;   Other: Placebo
Sponsors:   Massachusetts General Hospital;   National Institutes of Health (NIH);   American Diabetes Association
Terminated - verified April 2017

A Study of the Function of Hormones Present In Taste Buds

Conditions:   Diabetes;   Obesity;   Pre-Diabetes;   Metabolic Syndrome
Sponsor:   National Institute on Aging (NIA)
Completed - verified January 2, 2015

Effect of Vegetable Oils for Use by the Snack Food Industry on Plasma Lipid Levels and Inflammatory Markers

Conditions:   Hyperlipidemias;   Metabolic Syndrome X;   Cardiovascular Diseases
Intervention:   Behavioral: Comparison of cooking oils
Sponsor:   Tufts University
Active, not recruiting - verified April 2017

Effect of Leptin Therapy in the Treatment of Severe Insulin Resistance

Condition:   Insulin Resistance
Intervention:   Drug: Metreleptin
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified September 23, 2016