Metabolic Syndrome

Clinical Trial Finder

Many patients with metabolic syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Effect of Oral Cinnamon Intervention in Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Dietary Supplement: Cinnamon;   Dietary Supplement: Placebo
Sponsors:   Diabetes Foundation, India;   Institute of Home Economics, University of Delhi, India
Completed - verified May 2015

Effectiveness of Four Popular Diet Strategies for Weight Loss and Cardiac Risk Reduction

Conditions:   Obesity;   Cardiovascular Disease;   Metabolic Syndrome
Interventions:   Behavioral: Atkins Diet;   Behavioral: Zone Diet;   Behavioral: Weight Watchers Diet;   Behavioral: Ornish Diet
Sponsor:   Tufts Medical Center
Completed - verified May 2015

HDL Lipidomic, Proteomic and Functional Changes in Women After Eating Eggs

Conditions:   Overweight;   Obesity;   Metabolic Syndrome
Interventions:   Other: Whole egg;   Other: Yolk-free egg
Sponsor:   University of California, Davis
Recruiting - verified May 2015

The Impact of Metabolic Syndrome on Patients Undergoing Elective Laparotomy

Conditions:   Metabolic Syndrome;   Anesthesia;   Perioperative Outcome;   Complications
Intervention:   Procedure: Elective abdominal surgery
Sponsor:   University of Ioannina
Completed - verified May 2015

Over-night Effect of Dietary Fiber on Glucose Metabolism and Satiety

Conditions:   Obesity;   Metabolic Syndrome
Interventions:   Other: High levels of indigestible carbohydrates;   Other: Low levels of indigestible carbohydrates
Sponsor:   Lund University
Completed - verified May 2015

Effect of Two Diets With Different Content of Protein on Weight Loss in Adults With Metabolic Syndrome

Conditions:   Metabolic Syndrome X;   Weight Loss
Intervention:   Other: High protein diet
Sponsor:   Mexican National Institute of Public Health
Enrolling by invitation - verified May 2015

Galantamine Effects in Patients With Metabolic Syndrome

Condition:   Abdominal Obesity Metabolic Syndrome
Interventions:   Drug: Galantamine;   Drug: Placebo (for galantamine)
Sponsors:   University of Sao Paulo;   University of Nove de Julho;   Feinstein Institute for Medical Research
Active, not recruiting - verified May 2015

Study of the Effect of Testosterone Treatment on Metabolic Parameters and Urinary Symptoms in Bariatric Patients

Conditions:   Obesity;   Hypogonadism;   Prostatic Hyperplasia;   Insulin Resistance
Intervention:  
Sponsor:   University of Florence
Recruiting - verified May 2015

Effects of Physical Activity in Psychosis

Conditions:   Schizophrenia;   Substance Use
Interventions:   Other: Computer game skills training;   Other: Physical activity
Sponsors:   Sykehuset i Vestfold HF;   Stiftelsen Helse og Rehabilitering;   Norwegian Research network in Severe Mental Illness
Enrolling by invitation - verified May 2015

Study to Evaluate Safety and Efficacy of PreCrea® on Subjects With Higher Than Normal Blood Sugar Levels

Conditions:   Diabetes Mellitus;   Pre-Diabetes;   Hyperglycemia;   Metabolic Syndrome
Interventions:   Dietary Supplement: Study dietary supplement (PreCrea 600 mg capsules);   Dietary Supplement: Placebo
Sponsor:   Joe Fenn
Completed - verified May 2015

Blood Lipopolysaccharide (LPS) Rifaximin Study

Conditions:   Obese;   Insulin Resistance;   Metabolic Syndrome
Interventions:   Drug: Rifaximin SSD;   Other: Placebo
Sponsors:   Philip Kern;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified May 2015

Effect of Dapagliflozin Administration on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion

Condition:   Metabolic Syndrome X
Interventions:   Drug: Dapagliflozin;   Drug: Placebo
Sponsor:   University of Guadalajara
Completed - verified May 2015

Comprehensive Lifestyle Modification for Patients With Hypertension and Metabolic Syndrome: a Multicenter Randomized Controlled Trial

Conditions:   Hypertension;   Metabolic Syndrome
Interventions:   Behavioral: Comprehensive Lifestyle Modification;   Behavioral: DASH
Sponsors:   Universität Duisburg-Essen;   Kliniken Essen-Mitte;   Immanuel Hospital Berlin, Berlin, Germany;   Charité University Medical Center, Berlin, Germany;   University of Witten/Herdecke
Active, not recruiting - verified May 2015

Meta-Analyses of the Effect of Vegetable Protein for Animal Protein on Cardiometabolic Risk

Conditions:   Diabetes;   Prediabetes;   Metabolic Syndrome;   Dysglycemia;   Overweight;   Obesity;   Dyslipidemia;   Hypertension;   Gout;   Non-alcoholic Fatty Liver Disease (NAFLD);   Kidney Disease;   Kidney Injury;   Cardiovascular Disease
Intervention:  
Sponsors:   John Sievenpiper;   Canadian Institutes of Health Research  (CIHR);   Canada Research Chairs Endowment of the Federal Government of Canada;   Loblaw Companies Limited
Active, not recruiting - verified May 2015

Effect of Exercise on Metabolic Health

Condition:   Obesity
Intervention:   Other: Exercise
Sponsors:   University of Michigan;   American Diabetes Association
Recruiting - verified May 2015

Inflammation and Glycation in a General Adult Population

Condition:   Inflammation
Intervention:  
Sponsors:   Hospital Clinico Universitario de Santiago;   Medtronic
Completed - verified May 2015

The Effects of the Telomerase Activator TA-65 on Insulin Resistance, Inflammation, and Metabolic Syndrome

Conditions:   Metabolic Syndrome;   Insulin Resistance
Interventions:   Dietary Supplement: TA-65;   Dietary Supplement: Placebo
Sponsor:   University of Connecticut
Terminated - verified May 2015

Effect of Short Term Atypical Antipsychotic Administration Compared to Placebo on Hepatic Insulin Extraction

Condition:   Normal Non-fluency
Intervention:   Drug: Olanzapine
Sponsors:   Michael Rickels;   University of Pennsylvania
Completed - verified May 2015

Meta-analyses of Fructose-containing Sugars and Incident Cardiometabolic Disease

Conditions:   Overweight;   Obesity;   Dyslipidemia;   Hyperlipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Gout;   Hypertension;   Metabolic Syndrome;   Coronary Heart Disease;   Cardiovascular Disease
Intervention:  
Sponsors:   John Sievenpiper;   Calorie Control Council;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research  (CIHR)
Active, not recruiting - verified May 2015

Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome

Conditions:   Diabetes;   Prediabetes;   Dysglycemia;   Overweight;   Obesity;   Dyslipidemia;   Hypertension;   Metabolic Syndrome;   Cardiovascular Diseases
Intervention:   Other: Tree nuts
Sponsors:   John Sievenpiper;   The International Tree Nut Council Nutrition Research & Education Foundation;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research  (CIHR)
Completed - verified May 2015

Meta-analyses of the Effect of Dietary Pulses on Acute Postprandial Metabolic Control

Conditions:   Diabetes;   Prediabetes;   Dysglycemia;   Overweight;   Obesity;   Metabolic Syndrome;   Cardiovascular Disease
Intervention:   Other: Dietary pulses
Sponsors:   John Sievenpiper;   Pulse Canada;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research  (CIHR)
Active, not recruiting - verified May 2015

Meta-analysis of Fructose-Containing Sugar Sweetened Beverages (SSBs) and Weight Change

Conditions:   Overweight;   Obesity;   Diabetes;   Prediabetes;   Dysglycemia;   Metabolic Syndrome
Intervention:   Other: Fructose-containing sugar sweetened beverages
Sponsors:   John Sievenpiper;   Calorie Control Council;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research  (CIHR)
Active, not recruiting - verified May 2015

Effect of Bariatric Surgery "Digestive Adaptations III" on Cardiovascular Risk

Conditions:   Diabetes Mellitus;   Metabolic Syndrome;   Obesity;   Atherosclerosis
Intervention:   Procedure: Digestive Adaptations III surgery
Sponsors:   University of Sao Paulo;   Fundação de Amparo à Pesquisa do Estado de São Paulo
Active, not recruiting - verified May 2015

Dietary Fatty Acid Composition and Obesity-related Metabolic Abnormalities

Condition:   Overweight/Obese Women
Intervention:   Other: High Fat Diet
Sponsors:   University of Michigan;   Robert C. Atkins Foundation
Active, not recruiting - verified May 2015

Meta-analyses of Fructose and Cardiometabolic Risk

Conditions:   Dyslipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Overweight;   Obesity;   Gout;   Hypertension;   Non-alcoholic Fatty Liver Disease;   Metabolic Syndrome;   Cardiovascular Disease
Intervention:   Other: Dietary fructose
Sponsors:   John Sievenpiper;   Canadian Institutes of Health Research  (CIHR);   Canada Research Chairs Endowment of the Federal Government of Canada;   Calorie Control Council
Active, not recruiting - verified May 2015

Vitamin E Versus Vitamin E Plus Pentoxiphyllin in Patients With Nonalcoholic Steatohepatitis: A Prospective Randomized Clinical Trial

Condition:   Non Alcoholic Steatohepatitis
Interventions:   Drug: Vitamin E plus Pentoxiphyllin;   Drug: Vitamin E
Sponsor:   Institute of Liver and Biliary Sciences, India
Withdrawn - verified November 2011

Cardiovascular Risk Factors, Lipid Metabolism and Oxidative Stress

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   University of Roma La Sapienza
Recruiting - verified May 2015

16 Year Follow-up of the Erlangen Fitness and Prevention Study.

Conditions:   Osteoporosis;   Osteopenia;   Early Postmenopause
Intervention:   Procedure: physical exercise
Sponsors:   University of Erlangen-Nürnberg Medical School;   Behinderten und Rehabilitations-Sportverband Bayern;   Netzwerk Knochengesundheit e.V.
Active, not recruiting - verified May 2015

Metabolic Syndrome in Bone Marrow Transplant Survivors

Condition:   Metabolic Syndrome
Intervention:   Other: Diagnostic exams
Sponsor:   Nationwide Children's Hospital
Terminated - verified May 2015

Effectiveness of Pulse-Based Foods Combined With Exercise for Improving Components of the Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Behavioral: Aerobic exercise training;   Dietary Supplement: pulse based diet
Sponsor:   University of Saskatchewan
Completed - verified May 2015

Chronotherapy With Low-dose Aspirin for Primary Prevention

Condition:   Type 2 Diabetes
Interventions:   Drug: aspirin;   Drug: aspirin
Sponsor:   University of Vigo
Recruiting - verified May 2015

Prevention of Obesity in Women Via Estradiol Regulation

Condition:   Obesity
Interventions:   Drug: leuprolide acetate;   Drug: Estradiol Transdermal;   Behavioral: progressive resistance exercise training
Sponsors:   University of Colorado, Denver;   National Institute on Aging (NIA)
Completed - verified November 2009

Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the Early Menopause

Conditions:   Bone Diseases;   Metabolic Syndrome X;   Coronary Disease
Interventions:   Behavioral: exercise;   Behavioral: exercise + cimicifuga racemosa;   Behavioral: wellness control, placebo
Sponsors:   University of Erlangen-Nürnberg Medical School;   Siemens-Betriebskrankenkasse
Terminated - verified May 2015

Effects of Fish Oils on Inflammation and Insulin Resistance

Conditions:   Metabolic Syndrome;   Insulin Resistance
Interventions:   Drug: omega-3 fatty acid;   Drug: placebo
Sponsors:   Philip Kern;   GlaxoSmithKline;   National Institutes of Health (NIH)
Active, not recruiting - verified May 2015

Complications in Hypertension and Obesity

Conditions:   Metabolic Syndrome;   Hypertension;   Obesity;   Dyslipidemia;   Hyperglycemia
Intervention:  
Sponsor:   Federal North-West Medical Research Centre
Recruiting - verified May 2015

MK0916 in Patients With Type 2 Diabetes and Metabolic Syndrome (0916-005)

Conditions:   Diabetes Mellitus, Type 2;   Metabolic Syndrome
Intervention:   Drug: MK0916
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified May 2015

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