Metabolic Syndrome

Clinical Trial Finder

Many patients with metabolic syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Study to Evaluate Safety, Efficacy of PBI-4050 & Its Effect on Relevant Biomarkers in T2DM Patients With Metabolic Syndrome

Conditions:   Type 2 Diabetes Mellitus;   Metabolic Syndrome
Interventions:   Drug: PBI-4050;   Other: Placebo
Sponsor:   ProMetic Pharma SMT Limited
Not yet recruiting - verified March 2017

High-intensity Interval, Low Volume Training in Metabolic Syndrome

Conditions:   Metabolic Syndrome;   Insulin Resistance
Interventions:   Behavioral: HIIT-LV;   Behavioral: CAE
Sponsors:   Universidad de Antioquia;   Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología (COLCIENCIAS)
Recruiting - verified March 2017

Impact of Text Messaging in the Management of Non-alcoholic Fatty Liver Disease

Condition:   NAFLD and NASH
Intervention:   Behavioral: Text Messaging
Sponsor:   Ashwani Singal,MD
Completed - verified March 2017

Characterization of Metabolic and Brain Effects of Rising Glucagon During an Oral Glucose Challenge

Conditions:   Metabolic Syndrome;   Diabetes
Interventions:   Drug: Intravenous glucagon;   Drug: Intravenous saline
Sponsor:   University Hospital Tuebingen
Recruiting - verified February 2017

Preoperative Omega-3 Polyunsaturated Fatty Acids in Morbidly Obese to Reduce Liver Volume and Steatosis

Condition:   Morbid Obesity D009765
Interventions:   Drug: Omega-3 Fatty Acid;   Other: Placebo
Sponsor:   Centre Hospitalier Universitaire de Nice
Recruiting - verified December 2016

Impact of Aerobic Exercise on Metabolic Syndrome, Neurocognition and Empowerment in Individuals With Mental Disorders

Conditions:   Metabolic Syndrome;   Mental Disorders
Intervention:   Behavioral: Physical activity program
Sponsors:   Fundación Marques de Valdecilla;   Centro de Investigación Biomédica en Red de Salud Mental;   Instituto de Investigación Marqués de Valdecilla
Recruiting - verified March 2017

A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP4345 in Patients With Schizophrenia

Condition:   Schizophrenia
Interventions:   Drug: ASP4345;   Drug: Matching Placebo
Sponsor:   Astellas Pharma Global Development, Inc.
Recruiting - verified March 2017

Effect of D-allulose in Addition to Oral Sucrose Load

Condition:   Blood Glucose
Interventions:   Dietary Supplement: D-allulose;   Dietary Supplement: sucrose;   Other: Placebo
Sponsor:   University of Florida
Recruiting - verified March 2017

Effects of Interleukin-1 Beta on Low Testosterone Levels in Men With Obesity and Metabolic Syndrome

Conditions:   Hypogonadism;   Metabolic Syndrome X;   Obesity
Interventions:   Drug: Anakinra;   Drug: Sodium Chloride 0.9%
Sponsor:   Mirjam Christ-Crain
Recruiting - verified March 2017

Evaluation of Liver Grafts With FibroScan® Before Organ Retrieval in Patients With Brain Death

Conditions:   Tissue and Organ Harvesting;   Liver Transplantation;   Brain Death
Intervention:   Procedure: Fibroscan
Sponsor:   University Hospital, Limoges
Recruiting - verified March 2017

Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic Malignancies

Conditions:   Acute Lymphoblastic Leukemia/Lymphoma;   Myelodysplasia;   Acute Myelogenous Leukemia;   Juvenile Myelomonocytic Leukemia;   Chronic Myelogenous Leukemia
Sponsors:   Center for International Blood and Marrow Transplant Research;   Pediatric Blood and Marrow Transplant Consortium;   National Marrow Donor Program
Recruiting - verified March 2017

Metformin in Kidney Disease

Conditions:   Chronic Kidney Disease;   Cardiovascular Disease;   Metabolic Syndrome
Interventions:   Drug: metformin;   Drug: Placebo
Sponsor:   VA Office of Research and Development
Recruiting - verified March 2017

Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients

Conditions:   Liver Transplantation;   Metabolic Syndrome X;   Obesity
Interventions:   Other: Control group;   Other: Mediterranean diet;   Other: Protein-Sparing Modified Fast (PSMF)
Sponsor:   The Cleveland Clinic
Terminated - verified July 2014

Effects of Colchicine in Non-Diabetic Adults With Metabolic Syndrome

Conditions:   Obesity;   Metabolic Disease
Interventions:   Drug: Colchicine 0.6 mg given;   Drug: Placebo capsules given
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified February 17, 2017

Vitamin D and Vascular Health in Children

Conditions:   Obesity;   Vitamin D Deficiency
Intervention:   Dietary Supplement: Vitamin D3
Sponsors:   University of Pittsburgh;   National Heart, Lung, and Blood Institute (NHLBI);   Office of Dietary Supplements (ODS)
Recruiting - verified March 2017

Pattern of Gene Expression in Adipose Tissue From Patients With Cushing Syndrome

Condition:   Cushing Syndrome Related to Cortisolic Adenoma
Intervention:   Other: analyze the role of glucocorticoid in AT distribution.
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed - verified March 2017

Screening and Risk Factors of Colon Neoplasia

Condition:   Colon Cancer
Interventions:   Other: Stool DNA Test;   Procedure: biopsies of rectal and colon mucosa;   Other: Questionnaires
Sponsor:   Case Comprehensive Cancer Center
Recruiting - verified March 2017

Macronutrient Relations and Weight Loss in Obese Subjects

Condition:   Obesity
Interventions:   Other: energy-restricted, CHO-restricted diet;   Other: energy-restricted, CHO-rich diet
Sponsor:   Heart and Diabetes Center North-Rhine Westfalia
Completed - verified December 2013

The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study

Condition:   Metabolic Syndrome x
Interventions:   Drug: Study drugs: Metformin and fenofibrate;   Drug: Study Drug: Metformin;   Drug: Study Drug: fenofibrate;   Drug: Metformin and Fenofibrate placebo
Sponsors:   University of Pennsylvania;   Abbott
Completed - verified March 2017

Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)

Condition:   Hypercholesterolemia
Interventions:   Drug: simvastatin (+) ezetimibe;   Drug: atorvastatin
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified March 2017