Metabolic Syndrome

Clinical Trial Finder

Many patients with metabolic syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Short Term Intermittent Fasting and Insulin Resistance

Conditions:   Diabetes Mellitus;   Non-alcoholic Fatty Liver Disease;   Metabolic Syndrome;   Obesity
Interventions:   Behavioral: Intermittent fasting;   Other: Time control
Sponsors:   University of Copenhagen;   Herlev Hospital
Recruiting - verified April 2015

Whole-exome Sequencing in Childhood Obesity

Condition:   Childhood Obesity
Sponsors:   National University, Singapore;   National Medical Research Council (NMRC), Singapore;   Health Promotion Board, Singapore;   Genome Institute of Singapore A*Star, Singapore
Not yet recruiting - verified April 2015

The Early Warning System for the Diabetic Encephalopathy

Conditions:   Diabetes Mellitus Type 2;   Mild Cognitive Impairment;   Metabolic Syndrome X
Sponsor:   Tang-Du Hospital
Not yet recruiting - verified April 2015

Observational Study to Evaluate the Safety and Efficacy for Levacalm Tab. Versus Valsartan/Amlodipine Combination Therapy in Essential Hypertension Patients

Conditions:   Lower Leg Edema;   Orthostatic Hypertension
Interventions:   Drug: Levacalm;   Drug: Valsartan/amlodipine
Sponsor:   LG Life Sciences
Recruiting - verified April 2015

NPPV on Inflammatory Markers and Sleep in Severe Obese Patients With Metabolic Syndrome Undergone to Bariatric Surgery

Condition:   Metabolic Syndrome
Interventions:   Device: Noninvasive positive airway pressure flow generator device;   Procedure: Bariatric Surgery
Sponsor:   University of Nove de Julho
Recruiting - verified April 2015

Effectiveness of a Physical Therapy Program on Self-assessment Health and Quality of Life in Patients With Schizophrenia

Condition:   Schizophrenia
Intervention:   Other: A multimodal physiotherapy programme plus deep water running
Sponsors:   University of Malaga;   Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Not yet recruiting - verified December 2014

A Multi-Center Study of the CF Quantum® Sweat Test System

Condition:   Cystic Fibrosis
Intervention:   Device: Iontophoresis sweat test
Sponsor:   Polychrome Medical, Inc.
Not yet recruiting - verified March 2015

Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic Malignancies

Conditions:   Acute Lymphoblastic Leukemia/Lymphoma;   Myelodysplasia;   Acute Myelogenous Leukemia;   Juvenile Myelomonocytic Leukemia;   Chronic Myelogenous Leukemia
Sponsors:   Center for International Blood and Marrow Transplant Research;   Pediatric Blood and Marrow Transplant Consortium;   National Marrow Donor Program
Recruiting - verified April 2015

Effect of Two Diets With Different Content of Protein on Weight Loss in Adults With Metabolic Syndrome

Conditions:   Metabolic Syndrome X;   Weight Loss
Intervention:   Other: High protein diet
Sponsor:   Mexican National Institute of Public Health
Enrolling by invitation - verified April 2015

Insulin Sensitivity, Irisin and Adipokines as Outcome Parameters in Patients Undergoing Cardiac Surgery

Conditions:   Insulin Resistance;   Diabetes Mellitus Type 2;   Other Functional Disturbances Following Cardiac Surgery
Intervention:   Procedure: Cardiac surgery
Sponsors:   University Hospital, Basel, Switzerland;   McGill University
Recruiting - verified April 2015

Application of MT in Subjects With Overweight/Metabolic Abnormality---RCT

Conditions:   Overweight;   Metabolic Abnormality
Interventions:   Device: Mobile physical activity promotion tool;   Other: Standard care
Sponsor:   National Cheng-Kung University Hospital
Recruiting - verified April 2015

Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients

Conditions:   Serious Mental Illness;   Schizophrenia;   Schizoaffective Disorder;   Bipolar Disorder;   Cardiovascular Disease
Interventions:   Drug: Simvastatin;   Drug: Losartan
Sponsor:   Mclean Hospital
Recruiting - verified April 2015

Tart Cherry, Metabolic Syndrome, and Cardiovascular Risk

Conditions:   Metabolic Syndrome;   Cardiovascular Diseases;   Diabetes
Interventions:   Dietary Supplement: Tart Cherry;   Dietary Supplement: Placebo
Sponsors:   Florida State University;   Cherry Research Committee;   Cherry Marketing Institute
Recruiting - verified April 2015

Effects of Colchicine in Non-Diabetic Adults With Metabolic Syndrome

Conditions:   Obesity;   Metabolic Disease
Interventions:   Drug: Colchicine 0.6 mg given;   Drug: Placebo capsules given
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified March 2000

Canola Oil, Fibre and DHA Enhanced Clinical Trial

Condition:   Metabolic Syndrome
Interventions:   Dietary Supplement: Butter, sunflower and safflower oil;   Dietary Supplement: High Oleic Canola Oil and DHA (HOCO-DHA);   Dietary Supplement: Barley beta-glucan;   Dietary Supplement: HOCO-DHA and Barley beta-glucan
Sponsors:   University of Manitoba;   Canadian Institutes of Health Research  (CIHR);   Agriculture and Agri-Food Canada
Recruiting - verified March 2014

Impact of Consumption of Beta-glucans on the Intestinal Microbiota and Glucose and Lipid Metabolism

Conditions:   Metabolic Syndrome;   Dyslipidemia;   Obesity, Abdominal;   Hyperglycemia;   Hypertension
Interventions:   Dietary Supplement: Bread with added beta-glucans;   Dietary Supplement: Placebo Comparator: Bread without added beta-glucans
Sponsors:   Mlinotest Zivilska Industrija d.d.;   University of Ljubljana;   University Medical Centre Ljubljana
Enrolling by invitation - verified April 2015

Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal Hypercortisolism

Condition:   Mild Hypercortisolism
Intervention:   Drug: Mifepristone
Sponsor:   Mount Sinai School of Medicine
Recruiting - verified April 2015

A Parallel Study Evaluating the Effect of A-F Betafood® on Gallbladder and Liver Function.

Condition:   Gallbladder
Intervention:   Dietary Supplement: A-F Betafood
Sponsors:   KGK Synergize Inc.;   Standard Process Inc.
Active, not recruiting - verified April 2015

Health Protection & Promotion for Oregon Correctional Officers

Conditions:   Physical Activity;   Nutrition;   Health Promotion;   Stress, Psychological;   Metabolic Syndrome
Intervention:   Behavioral: Testing & Intervention
Sponsors:   Oregon Health and Science University;   National Institute for Occupational Safety and Health (NIOSH/CDC);   Oregon Healthy Workforce Center
Completed - verified April 2015

Cross-Sectional Iloperidone IVGTT

Conditions:   Schizophrenia;   Serious Mental Illness;   Metabolic Syndrome;   Insulin Resistance;   Glucose Metabolism
Sponsors:   David C. Henderson;   Novartis Pharmaceuticals
Recruiting - verified April 2015

The Effects of Oral Glucose Compared to Sweetener Drinking on Hormonal/Metabolic Responses

Condition:   Obesity
Interventions:   Other: glucose;   Other: sweetner
Sponsor:   Meir Medical Center
Completed - verified May 2014

Functional MRI Biomarkers of Cognitive Decrements in Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Metabolic Syndrome X;   Mild Cognitive Impairment
Sponsors:   Maastricht University Medical Center;   ZonMw: The Netherlands Organisation for Health Research and Development;   Netherlands Organisation for Scientific Research
Completed - verified April 2015

Impact of Muscle Insulin Resistance on the Pathogenesis of Non Alcoholic Steatohepatitis

Condition:   Non Alcoholic Fatty Liver Diseases (NAFLD)
Sponsor:   Mayo Clinic
Active, not recruiting - verified April 2015

Evaluation of Humira Retention Rate in Psoriasis Patients in Daily Practice and Assessment of Work Productivity and Quality of Life

Condition:   Psoriasis
Sponsors:   AbbVie (prior sponsor, Abbott);   Veeda Clinical Research
Completed - verified April 2015

Angiotensin-converting-enzyme (ACE) Inhibitors in Hemodialysis

Conditions:   Left Ventricular Hypertrophy;   Hypertension
Interventions:   Drug: ACE inhibitor Ramipril;   Drug: non-RAS inhibitor antihypertensive therapy
Sponsors:   Mario Negri Institute for Pharmacological Research;   Agenzia Italiana del Farmaco
Active, not recruiting - verified April 2015

Evaluation of Three Strategies of Second-line Antiretroviral Treatment in Africa (Dakar - Bobo-Dioulasso - Yaoundé)

Conditions:   HIV;   HIV Infections
Interventions:   Drug: emtricitabine/tenofovir + lopinavir/ritonavir (WHO recommended second line);   Drug: abacavir + didanosine + lopinavir/ritonavir (WHO recommended second line);   Drug: emtricitabine/tenofovir + darunavir + ritonavir (Second line strategy under evaluation)
Sponsors:   French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS);   Gilead Sciences;   Janssen Pharmaceutica
Active, not recruiting - verified April 2015

Hispanics With Metabolic Syndrome and Non-ischemic Heart Failure

Conditions:   Metabolic Syndrome;   Heart Failure
Sponsors:   Texas Tech University Health Sciences Center;   Health Resources and Services Administration (HRSA)
Withdrawn - verified April 2015

Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for Schizophrenia

Condition:   Metabolic Syndrome
Interventions:   Drug: Pravastatin, Fenofibrate, Metformin, Orlistat, irbesartan;   Other: As selected by community physician
Sponsor:   North Shore Long Island Jewish Health System
Terminated - verified November 2011

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