Metabolic Syndrome

Clinical Trial Finder

Many patients with metabolic syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Drug: Metformin;   Dietary Supplement: Agave inulin;   Other: Placebo of agave inulin;   Other: Metformin placebo
Sponsor:   Centro Universitario de Ciencias de la Salud, Mexico
Completed - verified May 2016

Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Drug: Metformin;   Dietary Supplement: Agave inulin;   Other: Placebo of agave inulin;   Other: Metformin placebo
Sponsor:   Centro Universitario de Ciencias de la Salud, Mexico
Completed - verified May 2016

Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism

Conditions:   Overweight;   Obesity;   Dysglycemia;   Prediabetes;   Metabolic Syndrome;   Type 2 Diabetes
Intervention:   Other: fructose, allulose, tagatose, or sorbose
Sponsors:   University of Toronto;   Canadian Diabetes Association;   The Physicians' Services Incorporated Foundation;   Banting and Best Diabetes Centre;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2016

Effect of Banaba (Lagerstroemia Speciosa) on Metabolic Syndrome, Insulin Secretion and Insulin Sensitivity

Condition:   Metabolic Syndrome X
Interventions:   Drug: Banaba;   Drug: placebo
Sponsor:   University of Guadalajara
Recruiting - verified May 2016

A Short Term Evaluation of a Structured Weight Loss Plan in Overweight and Obese Adults

Condition:   Metabolic Syndrome
Interventions:   Other: "Grab-and-Go" meal plan;   Other: "Jump-Start" meal plan
Sponsors:   University of Missouri-Columbia;   Atkins Nutritionals Company
Recruiting - verified May 2016

Effects of Propofol and Sevoflurane on Early POCD in Elderly Patients With Metabolic Syndrome

Condition:   Postoperative Complications
Intervention:   Other: metabolic syndrome
Sponsor:   General Hospital of Ningxia Medical University
Completed - verified May 2016

Assessment of the Prevalence of Small Fiber Peripheral Neuropathy Among Non-diabetic Obese Patients

Condition:   Neuropathology
Intervention:   Device: Exams
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Recruiting - verified May 2016

Breast Cancer WEight Loss Study (BWEL Study)

Conditions:   Ductal Breast Carcinoma in Situ;   Breast Carcinoma
Interventions:   Other: Health Education Program;   Other: Weight Loss Intervention
Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI);   Division of Cancer Control;   NIH Biomarker, Imaging and Quality of Life Studies Funding Program (BIQSFP)
Not yet recruiting - verified May 2016

A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP4345 in Patients With Schizophrenia

Condition:   Schizophrenia
Interventions:   Drug: ASP4345;   Drug: Matching Placebo
Sponsor:   Astellas Pharma Global Development, Inc.
Recruiting - verified May 2016

Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases

Conditions:   Diabetes Mellitus, Type 2;   Metabolic Syndrome X;   Hypertension;   Cardiovascular Diseases;   Stroke
Intervention:   Other: Fructose-containing Sugars
Sponsors:   University of Toronto;   Canadian Institutes of Health Research (CIHR);   The Physicians' Services Incorporated Foundation;   Canadian Diabetes Association (CDA)
Active, not recruiting - verified May 2016

Meta-analyses of Liquid Versus Solid Calories and Body Weight

Conditions:   Diabetes Mellitus;   Chronic Disease;   Cardiovascular Diseases;   Prediabetic State;   Overweight;   Obesity;   Metabolic Syndrome
Intervention:   Other: Liquid calories from sugars
Sponsors:   John Sievenpiper;   The Physicians' Services Incorporated Foundation;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2016

Replacing Refined Carbohydrates With Healthy Fats on Cardio-metabolic Markers

Conditions:   Pre-diabetes;   Metabolic Syndrome
Interventions:   Dietary Supplement: Active;   Dietary Supplement: Control
Sponsor:   Institute for Food Safety and Health, United States
Recruiting - verified May 2016

Meta-analyses of Nuts and Risk of Obesity

Conditions:   Body Weight;   Obesity;   Overweight;   Adiposity;   Obesity, Abdominal
Intervention:   Other: Dietary tree nuts & peanuts
Sponsors:   John Sievenpiper;   The Physicians' Services Incorporated Foundation
Active, not recruiting - verified September 2015

Non-invasive Liver Screening for Risk Assessment for Coronary Heart Disease

Conditions:   Coronary Disease;   Non-alcoholic Fatty Liver Disease;   Elasticity Imaging Techniques
Interventions:   Device: Fibro Scan;   Genetic: PNPLA3
Sponsors:   University of Leipzig;   Universitätsklinikum Leipzig
Recruiting - verified May 2016

Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease

Conditions:   Liver Disease;   Fatty Liver
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified January 2016

The Efficacy of Venavine Intensive® on the Quality of Life in Females With Chronic Venous Insufficiency

Condition:   Venous Insufficiency
Interventions:   Other: Gelatine Capsule;   Other: Venavine Intensive®
Sponsor:   University of Johannesburg
Completed - verified May 2016

Evaluation of Liver Grafts With FibroScan® Before Organ Retrieval in Patients With Brain Death

Conditions:   Tissue and Organ Harvesting;   Liver Transplantation;   Brain Death
Intervention:   Procedure: Fibroscan
Sponsor:   University Hospital, Limoges
Recruiting - verified May 2016

Effectiveness of a Physical Therapy Program on Self-assessment Health and Quality of Life in Patients With Schizophrenia

Condition:   Schizophrenia
Intervention:   Other: A multimodal physiotherapy programme
Sponsors:   University of Malaga;   Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Recruiting - verified September 2015

Soybean Oil Trial of cArdiovascular Risk

Conditions:   Cardiovascular Disease;   Diabetes;   Metabolic Syndrome
Interventions:   Other: Soybean oil;   Other: High-oleic soybean oil;   Other: High-oleic soybean oil + fully hydrogenated soybean oil;   Other: Palm olein + palm stearin
Sponsor:   USDA Beltsville Human Nutrition Research Center
Completed - verified May 2016

PilAm Go4Health Weight Loss Program to Prevent Heart Disease

Conditions:   Insulin Resistance,;   Metabolic Syndrome;   Type 2 Diabetes
Intervention:   Behavioral: PilAm Go4Health Weight-loss Program
Sponsor:   University of California, San Francisco
Active, not recruiting - verified May 2016

ENDOBARRIER® and Conventional Therapy in the Management of Metabolic Syndrome in Obese Patients

Condition:   Metabolic Syndrome
Intervention:   Device: ENDOBARRIER®
Sponsors:   University Hospital, Lille;   Ministry of Health, France
Suspended - verified May 2016

Trial of Diet in Gestational Diabetes Mellitus: Metabolic Consequences to Mother and Offspring

Condition:   Gestational Diabetes Mellitus
Interventions:   Behavioral: Low Carbohydrate/Conventional;   Behavioral: Choosing Healthy Options in Carbohydrate Energy
Sponsors:   University of Colorado, Denver;   National Institutes of Health (NIH)
Recruiting - verified May 2016

Impact of Ranolazine in Blood Markers in Women With Angina and Metabolic Syndrome

Conditions:   Stable Angina;   Metabolic Syndrome
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsor:   University of Florida
Recruiting - verified May 2016

Effect of Protein and Prebiotic Fiber Intake on Adiposity in Overweight and Obese Adults

Condition:   Obesity
Interventions:   Dietary Supplement: Protein;   Dietary Supplement: Prebiotic fiber;   Dietary Supplement: Protein plus prebiotic fiber;   Dietary Supplement: Control
Sponsors:   University of Calgary;   General Mills Inc.
Active, not recruiting - verified May 2016

Effects of Colchicine in Non-Diabetic Adults With Metabolic Syndrome

Conditions:   Obesity;   Metabolic Disease
Interventions:   Drug: Colchicine 0.6 mg given;   Drug: Placebo capsules given
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified March 2016

Study 2: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients

Condition:   Hypertension
Interventions:   Drug: Minocycline Group;   Other: Placebo Group
Sponsors:   University of Florida;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified May 2016

Study 1: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients

Condition:   Hypertension
Interventions:   Drug: Minocycline 100mg Group;   Drug: Minocycline 200mg Group
Sponsors:   University of Florida;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Role of Growth Hormone Antagonism in Modulating Insulin Sensitivity in Subjects With Pre-diabetes

Conditions:   Diabetes;   Metabolic Syndrome;   Insulin Resistance
Intervention:   Drug: pegvisomant
Sponsors:   University of California, San Francisco;   San Francisco General Hospital
Completed - verified May 2016

In Vitro Fertilization Outcomes in Metabolic Syndrome

Condition:   Metabolic Syndrome
Intervention:  
Sponsor:   Meir Medical Center
Completed - verified October 2013

Effects of Canola Oil on Vascular and Metabolic Parameters in Individuals With Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Other: Canola Oil 25 g/d;   Other: Non-Canola Oil Mixture 25 g/d
Sponsors:   University of Manitoba;   Alberta Innovates Bio Solutions;   Alberta Canola Producers Commission;   Canola Council of Canada
Completed - verified May 2016

SGA-induced Metabolic Syndrome in Bipolar Youth

Condition:   Bipolar Youth Treated With Second-generation Antipsychotics
Interventions:   Drug: Omega;   Drug: Placebo;   Drug: Quetiapine fumarate
Sponsors:   University of Cincinnati;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified May 2016

Exercise in Prevention of Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Behavioral: 1x4 aerobic interval training;   Behavioral: 4x4 aerobic interval training;   Behavioral: traditional moderate training
Sponsor:   Norwegian University of Science and Technology
Recruiting - verified May 2016

Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease

Conditions:   Overweight;   Obesity;   Dyslipidemia;   Hyperlipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Gout;   Hypertension;   Metabolic Syndrome;   Coronary Heart Disease;   Cardiovascular Disease
Intervention:  
Sponsors:   John Sievenpiper;   Calorie Control Council;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2016

Mifepristone for Metabolic Syndrome

Conditions:   Endocrine Disease;   Diabetes
Intervention:   Drug: Mifepristone
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified February 2016

Dietary Intervention for Visceral Adiposity

Condition:   Obesity
Interventions:   Dietary Supplement: Benefiber;   Dietary Supplement: TrueLemon
Sponsors:   Kirsten Hairston;   Wake Forest School of Medicine
Active, not recruiting - verified May 2016

A Study of Strawberries and Disease Risk

Conditions:   Nutritional and Metabolic Diseases;   Inflammation;   Physiological Responses
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: 10G;   Dietary Supplement: 20G;   Dietary Supplement: 40G;   Dietary Supplement: Placebonofiber
Sponsors:   Institute for Food Safety and Health, United States;   California Strawberry Commission
Active, not recruiting - verified May 2016

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

Conditions:   Asthma;   Atherosclerosis;   Metabolic Syndrome;   Insulin Resistance;   Cancer
Intervention:  
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Enrolling by invitation - verified November 2015

Reduction of the Metabolic Syndrome in Navarra-Spain

Conditions:   Metabolic Syndrome;   Obesity;   Diabetes;   Cardiovascular Disease
Interventions:   Behavioral: Crononutrition;   Behavioral: American Heart Association
Sponsors:   Clinica Universidad de Navarra, Universidad de Navarra;   Hospital of Navarra
Completed - verified November 2011

Assessing Inherited Markers of Metabolic Syndrome in the Young

Conditions:   Metabolic Syndrome;   Diabetes Mellitus, Type 2;   Obesity
Intervention:  
Sponsors:   Eric Hoffman;   National Institutes of Health (NIH);   Howard University;   University of Massachusetts, Worcester;   East Carolina University
Active, not recruiting - verified May 2016

Evaluation of Phlebotomy as a Treatment for Non-alcoholic Fatty Liver Disease

Condition:   Non-alcoholic Fatty Liver Disease
Intervention:   Procedure: Phlebotomy
Sponsor:   University of Western Ontario, Canada
Completed - verified May 2016

Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)

Condition:   Hypercholesterolemia
Interventions:   Drug: simvastatin (+) ezetimibe;   Drug: atorvastatin
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified May 2016

Effect of Leptin Therapy in the Treatment of Severe Insulin Resistance

Condition:   Insulin Resistance
Intervention:   Drug: Metreleptin
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified February 2016