High Cholesterol

Clinical Trial Finder

Many patients with high cholesterol are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Study to Evaluate the Effects of Dietary Fiber on Blood Lipids in Men and Women

Condition:   Hypercholesterolemia
Intervention:   Other: dietary fiber
Sponsors:   Tate & Lyle;   BioFortis
Recruiting - verified July 2016

Pediatric Preventative Health Screenings - Obesity and Family-Centered Outcomes

Conditions:   Obesity;   Overweight;   Blood Pressure;   Hypercholesteremia;   Diabetes
Intervention:   Behavioral: Motivational interviewing to elicit PCO in pediatrics
Sponsor:   Henry Ford Health System
Not yet recruiting - verified July 2016

Chart Review of Repatha® in Subjects With Hyperlipidaemia

Condition:   Hypercholesterolaemia
Intervention:  
Sponsor:   Amgen
Recruiting - verified July 2016

Pharmacokinetic and Pharmacodynamic Study of Bococizumab Alone and When Combined With Recombinant Human Hyaluronidase

Conditions:   Hypercholesterolemia;   Healthy
Interventions:   Biological: Cohort 1: bococizumab 150 mg + rHuPH20;   Biological: Cohort 2: bococizumab 300 mg;   Biological: Cohort 3: bococizumab 300 mg + rHuPH20;   Biological: Cohort 4: bococizumab 300 mg + rHuPH20;   Biological: Cohort 5: bococizumab 450 mg + rHuPH20
Sponsors:   Pfizer;   Halozyme Therapeutics
Active, not recruiting - verified July 2016

Comparing Effects of Liraglutide and Bariatric Surgery on Weight Loss, Liver Function, Body Composition, Insulin Resistance, Endothelial Function and Biomarkers of Non-alcoholic Steatohepatitis (NASH) in Obese Asian Adults

Conditions:   Non-alcoholic Fatty Liver Disease (NAFLD);   Weight Loss;   Non-alcoholic Steatohepatitis (NASH)
Interventions:   Behavioral: Lifestyle modification;   Drug: Liraglutide
Sponsor:   Changi General Hospital
Recruiting - verified July 2016

A Study to Assess the Safety and Efficacy of CAT-2054 in Combination With Atorvastatin in Patients With Hypercholesterolemia

Condition:   Hypercholesterolemia
Interventions:   Drug: CAT-2054;   Drug: Placebo;   Drug: Atorvastatin
Sponsor:   Catabasis Pharmaceuticals
Completed - verified July 2016

Atorvastatin Effectiveness and Safety in Cardiology Patients in Real World Setting

Condition:   Coronary Artery Disease, Hypercholesterolemia, Hypertension
Intervention:   Other: No intervention
Sponsor:   Pfizer
Not yet recruiting - verified July 2016

A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384)

Conditions:   Hypercholesterolemia;   Heterozygous Familial Hypercholesterolemia
Interventions:   Drug: EZ 10 mg/Atorva 20 mg FDC;   Drug: EZ 10 mg/Atorva 10 mg FDC
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified July 2016

Trial Assessing Efficacy, Safety and Tolerability of PCSK9 Inhibition in Paediatric Subjects With Genetic LDL Disorders

Condition:   Heterozygous Familial Hypercholesterolemia
Interventions:   Drug: Evolocumab;   Drug: Placebo
Sponsor:   Amgen
Recruiting - verified July 2016

Statins at the Primary Care Level

Condition:   Dyslipidemia
Intervention:   Other: Educational Intervention
Sponsor:   Institute for Clinical Effectiveness and Health Policy
Active, not recruiting - verified July 2016

GISSI Outliers CAPIRE

Condition:   Atherosclerosis
Intervention:  
Sponsor:   Gruppo di Ricerca GISSI
Active, not recruiting - verified July 2016

Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia

Conditions:   Dyslipidemia;   Hypercholesterolemia;   Hypertriglyceridemia
Interventions:   Drug: CAT-2003;   Drug: Placebo;   Drug: Statin
Sponsor:   Catabasis Pharmaceuticals
Completed - verified July 2016

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound

Condition:   Hypercholesterolemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo
Sponsor:   Amgen
Active, not recruiting - verified July 2016

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Active, not recruiting - verified July 2016

The Medication Experience Study

Conditions:   Hypertension;   Elevated Cholesterol;   Diabetes;   Depression
Intervention:   Other: Internet Survey
Sponsor:   Wake Forest University
Active, not recruiting - verified July 2016

Study of a Holistic Health Program for United Methodist Clergy

Conditions:   Obesity;   Depression;   Diabetes;   Hypertension;   Hypercholesterolemia
Intervention:   Behavioral: Holistic health
Sponsors:   Duke Clergy Health Initiative;   The Duke Endowment
Active, not recruiting - verified July 2016

Study to Assess the Tolerability and Efficacy of Anacetrapib Co-administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Conditions:   Hyperlipoproteinemia Type II;   Heterozygous Familial Hypercholesterolemia
Interventions:   Drug: Anacetrapib;   Drug: Placebo for Anacetrapib
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified July 2016

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

Conditions:   Diabetes;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Enrolling by invitation - verified July 2016

Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease Risk

Conditions:   Atherosclerosis;   Cardiovascular Diseases
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2009

Strong Heart Study

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Atherosclerosis;   Asthma;   Carotid Artery Diseases;   Coronary Disease;   Hypercholesterolemia;   Hypertension;   Diabetes Mellitus;   Obesity
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified May 2009

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Diabetes Mellitus;   Heart Diseases;   Hypercholesterolemia;   Hypertension;   Myocardial Infarction;   Myocardial Ischemia;   Heart Failure
Interventions:   Drug: Inhibitors, ACE;   Drug: amlodipine;   Drug: lisinopril;   Drug: doxazosin;   Drug: chlorthalidone;   Drug: pravastatin;   Behavioral: diet, fat-restricted
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2009