High Cholesterol

Clinical Trial Finder

Many patients with high cholesterol are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Study to Evaluate the Effects of Dietary Fiber on Blood Lipids in Men and Women

Condition:   Hypercholesterolemia
Intervention:   Other: dietary fiber
Sponsors:   Tate & Lyle;   BioFortis
Recruiting - verified July 2016

Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in Japan

Conditions:   Hypercholesterolemia;   Familial Hypercholesterolemia
Intervention:   Other: No intervention
Sponsor:   Amgen
Recruiting - verified July 2016

Chart Review of Repatha® in Subjects With Hyperlipidaemia

Condition:   Hypercholesterolaemia
Intervention:  
Sponsor:   Amgen
Recruiting - verified July 2016

Genetic Basis for Prediction of Non-responders to Dietary Plant Sterol Intervention

Conditions:   Hypercholesterolemia;   Cardiovascular Disease
Interventions:   Other: Plant sterols;   Other: Placebo
Sponsors:   University of Manitoba;   Mitacs;   Unilever R&D;   Nutritional Fundamentals for Health
Recruiting - verified July 2016

A Study in Subjects With Type 2 Diabetes Mellitus With Hypercholesterolemia/Mixed Dyslipidemia

Conditions:   Hypercholesterolemia;   Mixed Dyslipidemia;   Type 2 Diabetes
Interventions:   Biological: Evolocumab;   Other: Placebo to Evolocumab
Sponsor:   Amgen
Recruiting - verified July 2016

Pharmacokinetic and Pharmacodynamic Study of Bococizumab Alone and When Combined With Recombinant Human Hyaluronidase

Conditions:   Hypercholesterolemia;   Healthy
Interventions:   Biological: Cohort 1: bococizumab 150 mg + rHuPH20;   Biological: Cohort 2: bococizumab 300 mg;   Biological: Cohort 3: bococizumab 300 mg + rHuPH20;   Biological: Cohort 4: bococizumab 300 mg + rHuPH20;   Biological: Cohort 5: bococizumab 450 mg + rHuPH20
Sponsors:   Pfizer;   Halozyme Therapeutics
Active, not recruiting - verified July 2016

A Study to Assess the Safety and Efficacy of CAT-2054 in Combination With Atorvastatin in Patients With Hypercholesterolemia

Condition:   Hypercholesterolemia
Interventions:   Drug: CAT-2054;   Drug: Placebo;   Drug: Atorvastatin
Sponsor:   Catabasis Pharmaceuticals
Completed - verified July 2016

Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statin

Condition:   Hypercholesterolaemia
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Drug: placebo;   Drug: atorvastatin;   Drug: fenofibrate;   Drug: bezafibrate;   Drug: ezetimibe
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified July 2016

Exercise and Pharmacotherapy for Anxiety in Cardiac Patients

Conditions:   Anxiety;   Cardiovascular Disease
Interventions:   Drug: Lexapro;   Drug: Placebo;   Behavioral: Supervised Aerboic Exercise
Sponsor:   Duke University
Recruiting - verified July 2016

Trial Assessing Efficacy, Safety and Tolerability of PCSK9 Inhibition in Paediatric Subjects With Genetic LDL Disorders

Condition:   Heterozygous Familial Hypercholesterolemia
Interventions:   Drug: Evolocumab;   Drug: Placebo
Sponsor:   Amgen
Recruiting - verified July 2016

Statins at the Primary Care Level

Condition:   Dyslipidemia
Intervention:   Other: Educational Intervention
Sponsor:   Institute for Clinical Effectiveness and Health Policy
Active, not recruiting - verified July 2016

Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Condition:   Hypercholesterolemia
Intervention:   Biological: Evolocumab
Sponsor:   Amgen
Enrolling by invitation - verified July 2016

Study of a Holistic Health Program for United Methodist Clergy

Conditions:   Obesity;   Depression;   Diabetes;   Hypertension;   Hypercholesterolemia
Intervention:   Behavioral: Holistic health
Sponsors:   Duke Clergy Health Initiative;   The Duke Endowment
Active, not recruiting - verified July 2016

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

Conditions:   Diabetes;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Enrolling by invitation - verified July 2016