High Cholesterol

Clinical Trial Finder

Many patients with high cholesterol are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Study Assessing Safety, Immunogenicity and LDLc -Lowering Activity of 2 PCSK9 Targeting AFFITOPE Vaccines in Healthy Subjects

Condition:   Hypercholesterolemia
Interventions:   Biological: AFFITOPE® AT04A+adjuvant;   Biological: AFFITOPE® AT06A+adjuvant;   Biological: Adjuvant without active component
Sponsors:   Affiris AG;   Medical University of Vienna
Recruiting - verified July 2015

A Study to Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Condition:   Homozygous Familial Hypercholesterolemia (HoFH)
Intervention:   Drug: Rosuvastatin 20mg
Sponsor:   AstraZeneca
Active, not recruiting - verified July 2015

Evaluation of Alirocumab in Addition to Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia in South Korea and Taiwan

Condition:   Hypercholesterolemia
Interventions:   Drug: alirocumab SAR236553/REGN727;   Drug: placebo
Sponsor:   Sanofi
Recruiting - verified July 2015

A Study of Evacetrapib (LY2484595) in Japanese Participants With Primary Hypercholesterolemia

Condition:   Hypercholesterolemia
Interventions:   Drug: Evacetrapib;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Active, not recruiting - verified July 2015

Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Condition:   Hypercholesterolemia
Intervention:   Biological: Evolocumab
Sponsor:   Amgen
Enrolling by invitation - verified July 2015

A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol

Condition:   Hyperlipidemia
Interventions:   Drug: Evacetrapib;   Drug: Atorvastatin;   Drug: Ezetimibe;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting - verified July 2015

CEntralized Pan-Russian Survey of tHE Undertreatment of hypercholeSterolemia II (CEPHEUS II)

Condition:   Dyslipidaemia
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Condition:   Homozygous Familial Hypercholesterolemia (HoFH)
Interventions:   Drug: Rosuvastatin 20mg;   Drug: Placebo
Sponsor:   AstraZeneca
Completed - verified July 2015

Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II)

Condition:   Hypercholesterolemia
Interventions:   Drug: Alirocumab;   Drug: Placebo (for alirocumab)
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Active, not recruiting - verified July 2015

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia

Condition:   Heterozygous Familial Hypercholesterolemia
Interventions:   Drug: Bococizumab (PF-04950615;RN316);   Other: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

Open Label Study of Long Term Safety Evaluation of Alirocumab

Condition:   Hypercholesterolemia
Intervention:   Drug: Alirocumab SAR236553 (REGN727)
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified July 2015

Effect of Rice Bran and Cooked Navy Beans on Cholesterol Levels in Healthy Children

Condition:   Hyperlipidemia.
Interventions:   Dietary Supplement: Bean powder;   Dietary Supplement: Rice bran
Sponsors:   Poudre Valley Health System;   Colorado State University
Active, not recruiting - verified May 2015

Open Label Study of Long Term Evaluation Against LDL-C Trial-2

Condition:   Hyperlipidemia and Mixed Dyslipidemia
Interventions:   Biological: evolocumab (AMG 145) and standard of care;   Other: Standard of care
Sponsor:   Amgen
Recruiting - verified July 2015

Study of Metformin With Simvastatin for Men With Prostate Carcinoma

Condition:   Prostate Carcinoma
Interventions:   Drug: Metformin;   Drug: Simvastatin
Sponsor:   Nicholas Mitsiades
Withdrawn - verified July 2015

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

Conditions:   Diabetes;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Enrolling by invitation - verified July 2015

Statin/Vitamin D & Migraine Study

Condition:   Migraine
Interventions:   Drug: Simvastatin;   Dietary Supplement: Vitamin D;   Other: Placebo
Sponsor:   Rami Burstein
Active, not recruiting - verified July 2015

Lipid Efficacy/Tolerability Study (0524A-020)

Conditions:   Primary Hypercholesterolaemia;   Mixed Hyperlipidaemia
Interventions:   Drug: niacin (+) laropiprant;   Drug: ER-niacin
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

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