High Cholesterol

Clinical Trial Finder

Many patients with high cholesterol are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Study Assessing Safety, Immunogenicity and LDLc -Lowering Activity of 2 PCSK9 Targeting AFFITOPE Vaccines in Healthy Subjects

Condition:   Hypercholesterolemia
Interventions:   Biological: AFFITOPE® AT04A+adjuvant;   Biological: AFFITOPE® AT06A+adjuvant;   Biological: Adjuvant without active component
Sponsors:   Affiris AG;   Medical University of Vienna
Recruiting - verified July 2015

Renal Hemodynamic Effects of the HMG-CoA Reductase Inhibitors in Normal Volunteers and in Patients With Chronic Renal Failure

Conditions:   Hyperlipidemia;   Hypertension;   Chronic Renal Failure
Intervention:   Drug: Simvastatin
Sponsor:   Mayo Clinic
Completed - verified July 2015

A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol

Condition:   Hyperlipidemia
Interventions:   Drug: Evacetrapib;   Drug: Atorvastatin;   Drug: Ezetimibe;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting - verified July 2015

CEntralized Pan-Russian Survey of tHE Undertreatment of hypercholeSterolemia II (CEPHEUS II)

Condition:   Dyslipidaemia
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Evaluating PCSK9 Binding antiBody Influence oN coGnitive HeAlth in High cardiovascUlar Risk Subjects

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Recruiting - verified July 2015

Effect of Rice Bran and Cooked Navy Beans on Cholesterol Levels in Healthy Children

Condition:   Hyperlipidemia.
Interventions:   Dietary Supplement: Bean powder;   Dietary Supplement: Rice bran
Sponsors:   Poudre Valley Health System;   Colorado State University
Active, not recruiting - verified May 2015

Open Label Study of Long Term Evaluation Against LDL-C Trial-2

Condition:   Hyperlipidemia and Mixed Dyslipidemia
Interventions:   Biological: evolocumab (AMG 145) and standard of care;   Other: Standard of care
Sponsor:   Amgen
Recruiting - verified July 2015

Study of Metformin With Simvastatin for Men With Prostate Carcinoma

Condition:   Prostate Carcinoma
Interventions:   Drug: Metformin;   Drug: Simvastatin
Sponsor:   Nicholas Mitsiades
Withdrawn - verified July 2015

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

Conditions:   Diabetes;   Cardiovascular Disease
Sponsor:   National Human Genome Research Institute (NHGRI)
Enrolling by invitation - verified July 2015

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Conditions:   Atherosclerosis;   Hypercholesterolemia
Interventions:   Drug: Statin Drugs;   Other: HMG-CoA Reductase Inhibitors
Sponsor:   National Institutes of Health Clinical Center (CC)
Active, not recruiting - verified April 2015

Statin/Vitamin D & Migraine Study

Condition:   Migraine
Interventions:   Drug: Simvastatin;   Dietary Supplement: Vitamin D;   Other: Placebo
Sponsor:   Rami Burstein
Active, not recruiting - verified July 2015

A Study of Niaspan on Endothelium-Dependent and Endothelium-Independent Vascular Reactivity (0000-093)

Condition:   Dyslipidemia
Interventions:   Drug: Niaspan;   Drug: Comparator: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

Lipid Efficacy/Tolerability Study (0524A-020)

Conditions:   Primary Hypercholesterolaemia;   Mixed Hyperlipidaemia
Interventions:   Drug: niacin (+) laropiprant;   Drug: ER-niacin
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified July 2015

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