Heart Failure

Clinical Trial Finder

Many patients with heart failure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

NT-proBNP Measurements to Rule-out Heart Failure Among Patients With Atrial Fibrillation: A Prospective Clinical Study

Conditions:   Atrial Fibrillation;   Heart Failure
Sponsors:   University of Aarhus;   Randers Regional Hospital
Not yet recruiting

Heart Failure in Southern Sweden

Conditions:   Heart Failure,Congestive;   Drug Use;   Patient Care
Intervention:   Behavioral: Educational outreach visit
Sponsor:   Region Skane
Not yet recruiting

Prospective Observational Study of the Sacubitril-Valsartan Treatment Effectiveness.

Condition:   Heart Failure
Intervention:   Drug: Sacubitril-Valsartan
Sponsor:   Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

A Tele-Health Symptom Management Program for Patients With Heart Failure: Pall-Heart

Condition:   Heart Failure
Intervention:   Behavioral: Gentle Stretching
Sponsors:   University of Virginia;   University of Kentucky
Enrolling by invitation

Heart Failure Decompensation And In-Hospital Mortality

Conditions:   Chronic Heart Failure;   Decompensated Heart Failure;   Morality
Sponsor:   University of Roma La Sapienza
Not yet recruiting

Patients With Heart Failure With Preserved Ejection Fraction Adherence to ASV Therapy Pilot Registry (PEP ASV Pilot Registry)

Conditions:   Sleep Disorder; Breathing-Related;   Heart Failure
Intervention:   Behavioral: Active Patient Engagement
Sponsors:   Thomas Jefferson University;   Inova Fairfax Hospital;   Heart and Diabetes Center North Rhine-Westphalia;   CLEMENS HOSPITAL;   Resmed Inc

Study of Sacubitril/ValsarTan on MyocardIal OxygenatioN and Fibrosis in Heart Failure With Preserved Ejection Fraction

Condition:   Heart Failure With Preserved Ejection Fraction
Intervention:   Drug: Sacubitril-Valsartan
Sponsor:   Flinders University
Not yet recruiting

Effectiveness and Implementation of the Assessment of Burden of Chronic Conditions (ABCC)-Tool

Conditions:   Chronic Obstructive Pulmonary Disease;   Asthma;   Diabetes Mellitus, Type 2;   Heart Failure
Intervention:   Device: Assessment of Burden of Chronic Conditions (ABCC)-tool
Sponsors:   Maastricht University;   Netherlands Instititute for Health Services Research;   TNO;   University of Twente


Condition:   Cardiac Resynchronization Therapy, Non-LBBB, QRS Area
Intervention:   Device: Cardiac resynchronization therapy
Sponsors:   Maastricht University Medical Center;   Medtronic

Personalized Experiences to Inform Improved Communication for Patients With Life Limiting Illness

Conditions:   Heart Failure;   Renal Failure
Intervention:   Behavioral: Narrative Intervention
Sponsors:   University of Colorado, Denver;   National Institute of Nursing Research (NINR)
Enrolling by invitation

Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation

Condition:   Severe Cardiac Insufficiency
Intervention:   Biological: Blood sample
Sponsor:   Rennes University Hospital
Not yet recruiting

Long Term Arrhythmia Risk and Cardiovascular Events in Hemtopoietic Stem Cell Transplant Survivors: Reveal Linq Cancer Registry Study

Conditions:   Hematopoietic Stem Cell Transplant;   Atrial Fibrillation;   Atrial Flutter
Intervention:   Other: HSCT Patients
Sponsors:   University of South Florida;   Medtronic
Not yet recruiting

Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Drug: Metoprolol
Sponsor:   University Hospital, Motol
Not yet recruiting

Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis

Condition:   Myocardial Infarction
Intervention:   Other: Stress Challenge
Sponsors:   Emory University;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Prospective Clinical Registry of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) (S-ICD Korea Registry)

Conditions:   Heart Failure;   Sudden Cardiac Death;   Ventricular Tachycardia
Sponsor:   Yonsei University

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

Conditions:   Sleep Disordered Breathing;   Able Bodied
Interventions:   Drug: Acetazolamide + supplemental oxygen + PAP therapy;   Drug: Zolpidem + PAP therapy;   Drug: Buspirone + PAP therapy
Sponsor:   VA Office of Research and Development
Not yet recruiting

Image Location and Performance of Left Bundle Branch Pacing

Conditions:   Cardiac Pacing;   Pacing Therapy
Sponsor:   Medtronic Cardiac Rhythm and Heart Failure

Diastolic Dysfunction in Morbidly Obese Patients Undergo Bariatric Surgery

Conditions:   Diastolic Dysfunction;   Morbid Obesity
Sponsor:   Mahidol University
Not yet recruiting

Hospital-Community-Family-Care Management Platform for Atrial Fibrillation (HCF-CMP-AF)

Conditions:   Telemedicine;   Atrial Fibrillation
Interventions:   Other: Hospital-Community-Family-Care Management Platform Online;   Other: Subjects with AF conventional treatment
Sponsor:   Northern Jiangsu Province People's Hospital
Not yet recruiting

Fastigial Nucleus Stimulation for Coronary Heart Disease

Condition:   Coronary Disease
Interventions:   Device: Fastigial Nucleus Stimulation;   Drug: Standard treatment
Sponsors:   Affiliated Hospital of North Sichuan Medical College;   the Third Hospital of Mianyang
Enrolling by invitation

Cost-effectiveness and Safety of the CADScorSystem in Patients With Symptoms Suggestive of Stable Coronary Artery Disease.

Condition:   Angina, Stable
Intervention:   Device: CAD-score
Sponsors:   Bispebjerg Hospital;   Region Hovedstaden;   Larix A/S;   Acarix;   Kai Hansens Fond;   Kai Houmann Nielsens Fond
Active, not recruiting

IDE Trial for Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: POLARx™ Cardiac Cryoablation System
Sponsor:   Boston Scientific Corporation
Not yet recruiting

Evaluate the Efficacy and Safety of Roxadustat for the Treatment of Anemia and Risks of Cardiovascular and Cerebrovascular Events in ESRD Newly Initiated Dialysis Patients

Condition:   Anemia in Incident Dialysis Patients
Interventions:   Drug: Roxadustat;   Drug: Epoetin Alfa
Sponsor:   Second Xiangya Hospital of Central South University

Prospective Multicenter Study for Early Evaluation of Acute Chest Pain

Conditions:   Chest Pain;   Acute Aortic Dissection;   Pulmonary Embolism;   Acute Myocardial Infarction Type 1;   Acute Coronary Syndrome
Interventions:   Diagnostic Test: Coronary angiography;   Diagnostic Test: CT angiography of aorta;   Diagnostic Test: CT angiography of pulmonary arteries.;   Diagnostic Test: Electrocardiogram;   Diagnostic Test: Cardiac Troponin
Sponsor:   West China Hospital
Not yet recruiting

Comparative Imaging Assessment of Valvular Heart Disease

Conditions:   Valve Heart Disease;   Aortic Stenosis;   Aortic Regurgitation
Interventions:   Diagnostic Test: MRI with strain measurement;   Diagnostic Test: Echocardiography
Sponsor:   The Cleveland Clinic

Bilateral Pecto Intercostal Fascial Plane Block After Open Heart Surgeries

Condition:   Pain, Chest
Interventions:   Device: ultrasound;   Drug: Bupivacaine Hydrochloride 5 MG/ML
Sponsor:   Fayoum University Hospital
Not yet recruiting

GaStroEsophageal effeCt of indobUfen Versus aspiRin in Patients Undergoing Dual antiplatElet Therapy

Conditions:   Coronary Artery Disease;   Gastroesophageal Reflux Disease
Interventions:   Drug: Indobufen and aspirin mimetic;   Drug: Aspirin and indobufen mimetic
Sponsor:   Beijing Anzhen Hospital
Not yet recruiting

Identifying Most Effective Treatment Strategies to Control Arterial Hypertension in Sub-Saharan Africa

Condition:   Arterial Hypertension
Interventions:   Other: dual combination;   Other: triple combination;   Other: Standard of care
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Fund for Scientific Research
Not yet recruiting

Muscular Respiratory Involvement and Systemic Sclerosis

Conditions:   Systemic Sclerosis;   Diaphragm Defect;   Respiratory Insufficiency;   Pulmonary Function Test;   Diaphragmatic Electromyography;   Muscular Weakness
Intervention:   Diagnostic Test: Pulmonary function test
Sponsor:   Poitiers University Hospital
Not yet recruiting

Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery

Condition:   Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery Requiring Extracorporeal Circulation
Intervention:   Procedure: Coronary Artery Bypass Graft (CABG)
Sponsor:   University Hospital Center of Martinique

Value of Diaphragmatic Motion Measurement at Ultrasonography to Predict Poor Prognosis in Emergency Department Patients With Acute Respiratory Failure

Conditions:   Dyspnea;   Acute Respiratory Failure
Sponsors:   University Hospital, Montpellier;   Poitiers University Hospital;   University Hospital, Brest;   Nord-Vienne Hospital
Not yet recruiting

Role of Atosiban in Recurrent Implantation Failure

Condition:   Recurrent Implantation Failure
Sponsor:   Al Baraka Fertility Hospital
Not yet recruiting