Heart Failure

Clinical Trial Finder

Many patients with heart failure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Chronic Heart Failure Therapy Optimization With CardioRenal Remote Monitoring System (HERMESHF)

Condition:   Heart Failure
Intervention:   Device: ExpHeart
Sponsor:   CardioRenal
Not yet recruiting

Effects of Empagliflozin on Diuresis and Renal Function in Patients With Acute Decompensated Heart Failure

Condition:   Acute Decompensated Heart Failure
Intervention:   Drug: Empagliflozin 25 mg
Sponsors:   Christian Schulze;   Boehringer Ingelheim;   Zentrum für Klinische Studien Jena
Not yet recruiting

Effect of Physical Training in Patients With Heart Failure Caused by Chemotherapy for Cancer Treatment

Conditions:   Insufficiency;Cardiac;   Cancer;   Cardiotoxicity;   Heart Failure
Intervention:   Other: exercise training
Sponsors:   University of Sao Paulo General Hospital;   InCor Heart Institute;   Cancer Institute of Sao Paulo;   Hospital Sirio-Libanes

Clinical Study to Assess Safety, PK and PD Parameters of CDR132L

Condition:   Heart Failure
Intervention:   Drug: CDR132L
Sponsor:   Cardior Pharmaceuticals GmbH

Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy.

Conditions:   Cardiotoxicity;   Heart Failure;   Dilated Cardiomyopathy
Interventions:   Diagnostic Test: Echocardiography with speckle tracking analysis.;   Diagnostic Test: 48-hour ECG monitoring.;   Diagnostic Test: Blood samples analysis.
Sponsor:   Moscow State University of Medicine and Dentistry

Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction

Conditions:   Myocardial Infarction;   Vascular Stiffness;   Heart Failure
Intervention:   Other: Imaging evaluation for vascular assessment
Sponsors:   University Hospital, Lille;   Fédération Française de Cardiologie;   Merck Sharp & Dohme Corp.
Not yet recruiting

PIONEER Trial:Hemodynamic Support With ECMO and IABP in Elective Complex High-risk PCI

Conditions:   Coronary Artery Disease;   Heart Failure
Intervention:   Device: extracorporeal membrane oxygenation
Sponsors:   Xijing Hospital;   The First Affiliated Hospital of Zhengzhou University;   Bethune International Peace Hospital;   Beijing Anzhen Hospital;   The Second Affiliated Hospital of Harbin Medical University;   General Hospital of Northern Theater Command
Not yet recruiting

BedMed-Frail: Does the Potential Benefit of Bedtime Antihypertensive Prescribing Extend to Frail Populations?

Conditions:   Hypertension;   Dementia
Intervention:   Other: Bedtime administration of the participant's pre-existing antihypertensive medications
Sponsors:   University of Alberta;   Alberta Innovates Health Solutions;   Canadian Institutes of Health Research (CIHR);   EnACt
Not yet recruiting

NT-proBNP Levels and Obesity in Pregnancy

Conditions:   Obesity;   Pregnancy Complications;   Peripartum Cardiomyopathy
Intervention:   Diagnostic Test: NT-proBNP
Sponsor:   Duke University

Hemodynamic Effects of BPA at Rest and During Exercise in CTEPH

Condition:   Chronic Thromboembolic Pulmonary Hypertension
Intervention:   Diagnostic Test: Invasive exercise testing
Sponsors:   Aarhus University Hospital;   Nagoya University;   Department of Pulmonary Circulation and Thromboembolic Diseases, Medical Center for Postgraduate Med
Not yet recruiting

Bivalirudin in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention.

Conditions:   Acute Coronary Syndrome;   Percutaneous Coronary Intervention;   Aging;   Anticoagulants and Bleeding Disorders
Interventions:   Drug: Bivalirudin;   Drug: Heparin
Sponsors:   The First Affiliated Hospital of Dalian Medical University;   Beijing Friendship Hospital

Evaluation of Hemodynamic Parameters Following Transjugular Intrahepatic Portosystemic Shunt (TIPS)

Condition:   Refractory Ascites
Interventions:   Procedure: Study - Transjugular Intrahepatic Portosystemic Shunt (TIPS);   Procedure: Control - Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Sponsors:   Medical College of Wisconsin;   Radiological Society of North America
Not yet recruiting

Cone Beam CT Guided Transbronchial Cryobiopsy

Condition:   ILD
Intervention:   Procedure: cone beam CT guided transbronchial cryobiopsy
Sponsor:   China-Japan Friendship Hospital

Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications

Conditions:   Lymphoma;   Chemotherapeutic Toxicity
Intervention:   Other: Blood test for determination of CHIP
Sponsors:   Sunnybrook Health Sciences Centre;   The Leukemia and Lymphoma Society;   Queen's University

Diet and Exercise Frailty Intervention in Cardiac Device Patients

Conditions:   Frailty;   Cardiovascular Diseases
Intervention:   Other: Exercise and Nutritional Supplement
Sponsor:   Population Health Research Institute
Not yet recruiting

Application of Ultrasound Integrated Precision Diagnosis Technology in Prevention of Kidney Disease and Its Progress

Conditions:   Diagnostic Imaging;   Diagnosis;   Kidney Disease
Intervention:   Diagnostic Test: Ultrasound Integrated Precision Diagnosis Technology(ultrasound elastography)
Sponsors:   RenJi Hospital;   China-Japan Friendship Hospital;   Duke University

Association of PeriOPerative Aspirin-ResisTance and CardioVascular Outcome

Condition:   Myocardial Injury
Sponsor:   University Hospital Heidelberg
Not yet recruiting

Precision Medicine in Chinese Patients With Young Onset Diabetes

Condition:   Type 2 Diabetes
Interventions:   Other: Biogenetic explanation and endocrinologist intensive managment;   Other: Usual care management
Sponsor:   Chinese University of Hong Kong
Not yet recruiting

The Effects of Degenerative Mitral Regurgitation on Cardiac Structure and Function, Symptoms, and Exercise Capacity

Condition:   Mitral Regurgitation
Sponsor:   Atlantic Health System

LEft VEntricuLar Activation Time Shortening With Hisian Pacing vs Biventricular Resinchronization Therapy

Conditions:   His Bundle Pacing;   Resynchronization Therapy
Interventions:   Device: Lead placed in the His bundle in order to achieve QRS shortening.;   Device: Lead is placed in a tributary of the coronary sinus.
Sponsors:   Josep Lluis Mont Girbau;   Institut d'Investigacions Biomèdiques August Pi i Sunyer;   Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV)
Not yet recruiting

Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:   Biological: Allogeneic umbilical cord mesenchymal stem cells
Sponsor:   Ever Supreme Bio Technology Co., Ltd.

Safety and Effectiveness of Agent Paclitaxel-Coated PTCA Balloon Catheter. (AGENT Japan SV)

Condition:   Coronary Artery Disease
Interventions:   Device: Device: Paclitaxel-Coated PTCA Balloon Catheter;   Device: SeQuent Please Drug Eluting Balloon Catheter with Paclitaxel
Sponsor:   Boston Scientific Corporation
Not yet recruiting

The Heartflow Coronary Disease Progression Evaluation Study

Condition:   Coronary Artery Disease
Intervention:   Diagnostic Test: Coronary computed tomography angiography
Sponsor:   Erasmus Medical Center

Ticagrelor Compared to Clopidogrel in Acute Coronary Syndromes

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Ticagrelor 90mg;   Drug: Clopidogrel 75mg;   Drug: acetylsalicylic acid (ASA) 81mg
Sponsors:   McGill University Health Center;   Canadian Institutes of Health Research (CIHR)

FFR-CT to Detect the Absence of Hemodynamically Significant Lesions in Patients With High-risk Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Diagnostic Test: FFR-CT;   Diagnostic Test: FFRangio™
Sponsor:   Centre Hospitalier Universitaire Vaudois
Not yet recruiting

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