Heart Failure

Clinical Trial Finder

Many patients with heart failure are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Heart Failure Event Advance Detection Trial

Conditions:   Congestive Heart Failure;   Heart Failure;   Decompensated Heart Failure
Intervention:   Diagnostic Test: Indicor
Sponsors:   Vixiar Medical, Inc.;   Johns Hopkins University;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Effects of a Self-regulation Program on Self-care Behaviour of Heart Failure Patients

Condition:   Heart Failure
Intervention:   Behavioral: self-regulation programme
Sponsor:   National Yang Ming University

Liberal Use of Sodium in Ambulatory Heart Failure

Condition:   Heart Failure
Intervention:   Dietary Supplement: Sodium chloride
Sponsor:   Ziekenhuis Oost-Limburg
Not yet recruiting

Impact of Sacubitril/Valsartan on Quality of Life and Mortality of CKD vs Non-CKD in Heart Failure Patients

Conditions:   Heart Failure NYHA Class IV;   Heart Failure NYHA Class II
Intervention:   Drug: Sacubitril / Valsartan Oral Tablet
Sponsor:   Clinision

Retrospective Observational Analysis of a Cohort With Heart Failure With Preserved Ejection Fraction

Condition:   Heart Failure With Preserved Ejection Fraction
Intervention:   Other: No intervention, observational only
Sponsors:   Portsmouth Hospitals NHS Trust;   Manchester Metropolitan University
Not yet recruiting

Evaluation on Performance and Oxydative Stress in Patient With Iron deficIency and Stable Heart Failure Study

Conditions:   Chronic Heart Failure (CHF);   Iron Deficiency
Interventions:   Drug: Iron Sucrose IV;   Drug: Ferric polymaltose hydroxide complex IM;   Other: Saline solution

Volume Optimization Incorporating Negative Pressure Diuresis in Heart Failure (VOID-HF)

Condition:   Cardiorenal Syndrome
Intervention:   Device: JuxtaFlow System
Sponsor:   3ive Labs
Not yet recruiting

Comparison of Different Frailty Assessment Tools

Condition:   Heart Failure
Intervention:   Diagnostic Test: Frailty Assessment
Sponsors:   German Heart Institute;   The German Heart Foundation

Mechanical Dyssynchrony in CRT

Conditions:   Left Ventricular Dyssynchrony;   Heart Failure;   Cardiomyopathy, Dilated;   Cardiac Remodeling, Ventricular
Interventions:   Device: Cardiac resynchronization therapy;   Other: Conservative treatment
Sponsor:   Universitaire Ziekenhuizen Leuven
Not yet recruiting

Strain Imaging in Patients With Functional Mitral Regurgitation, Treated With MitraClip

Conditions:   Mitral Regurgitation;   Heart Failure
Intervention:   Diagnostic Test: speckle tracking analysis of transthoracic echocardiogram
Sponsor:   University of Athens

Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD

Condition:   Degenerative Disc Disease
Interventions:   Procedure: Anterior Cervical Discectomy and Fusion;   Device: Posterior Cervical Stabilization System (PCSS)
Sponsor:   Providence Medical Technology, Inc.
Not yet recruiting

Mechanisms and Innovations in Cardiac Resynchronisation Therapy

Conditions:   Heart Failure;   Left Ventricular Systolic Dysfunction;   Left Bundle-Branch Block;   Right Bundle-Branch Block;   Non-Specific Intraventricular Conduction Defect
Intervention:   Device: His-bundle pacing.
Sponsor:   Imperial College London

The Left Ventricular Assist Device(LVAD) Off or On Pump Implantation Study

Conditions:   Heart Failure;   LVAD
Interventions:   Device: Off-Pump;   Device: On-Pump
Sponsor:   The University of Texas Health Science Center, Houston
Not yet recruiting

A Study to Assess the Effect AZD4831 in Japanese and Chinese Healthy Volunteers

Condition:   Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions:   Drug: AZD4831;   Drug: Placebo
Sponsors:   AstraZeneca;   Parexel
Not yet recruiting

Two- Dimensional Speckle Tracking Echocardiography After Primary Percutaneous Coronary Intervention

Condition:   Myocardial Infarction
Intervention:   Procedure: 2D speckle tracking echocardiography
Sponsor:   Assiut University
Not yet recruiting

Identification of Prognostic Parameters in Patients With " Senile " Amyloid Cardiomyopathy

Condition:   Cardiac Amyloidosis
Sponsor:   University Hospital, Grenoble
Not yet recruiting

Natural History of Oculomotor Neurophysiology in Ataxic and Pre-ataxic Carriers of SCA3/MJD

Conditions:   Spinocerebellar Ataxia Type 3;   Machado-Joseph Disease
Interventions:   Diagnostic Test: Video-oculography;   Diagnostic Test: Clinical Scales;   Diagnostic Test: Genotyping
Sponsor:   Hospital de Clinicas de Porto Alegre
Active, not recruiting

Training Single Arm

Condition:   Pulmonary Hypertension
Intervention:   Other: exercise and respiratory therapy
Sponsor:   Heidelberg University

Extracorporeal Photopheresis and Early Cardiac Graft Vasculopathy

Conditions:   Cardiac Allograft Vasculopathy;   Heart Transplant Rejection
Intervention:   Procedure: Extracoropreal photopheresis
Sponsors:   Bosko Skoric;   University of Zagreb

Reverse Remodeling After PTSMA in Severe But Asymptomatic LVOT Obstruction

Conditions:   HOCM, Hypertrophic Obstructive Cardiomyopathy;   LVOTO - Left Ventricular Outflow Tract Obstruction;   Remodeling, Ventricular
Intervention:   Procedure: PTSMA
Sponsor:   St. Antonius Hospital
Not yet recruiting

Ertugliflozin for Functional Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Left Ventricular Systolic Dysfunction
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Asan Medical Center;   Merck Sharp & Dohme Corp.
Not yet recruiting

Noninvasive 3D Mapping in Persistent Atrial Fibrillation, to Describe Modifications of the Arrhythmogenic Substrate After Pulmonary Vein Isolation and Identify Potential Predicting Factors of Ablation Success

Condition:   Atrial Fibrillation, Persistent
Interventions:   Device: Noninvasive mapping (Cardioinsight® system);   Device: long-term cardiac monitoring (LINQ system);   Procedure: Atrial Fibrillation ablation procedure
Sponsor:   University Hospital, Rouen
Not yet recruiting

NT-proBNP Levels in the Prediction of Intrapartum and Postpartum Events in Adult Congenital Heart Disease Patients

Conditions:   Congenital Heart Disease;   Pregnancy Complications
Intervention:   Diagnostic Test: NT-proBNP
Sponsor:   Mayo Clinic

Use of Oral Anticoagulants and Symptoms in Patients With Atrial Fibrillation in Örebro County

Conditions:   Atrial Fibrillation;   Stroke, Ischemic
Intervention:   Drug: Oral anticoagulant
Sponsor:   Region Örebro County

T1-mapping by Cardiovascular Magnetic Resonance Imaging to Assess Non-Alcoholic Fatty Liver Disease

Conditions:   NAFLD;   Heart Failure;   Valvular Disease;   Coronary Disease
Intervention:   Diagnostic Test: T1 mapping on Cardiovascular Magnetic Resonance Studies
Sponsor:   Dr. Andreas Kammerlander
Not yet recruiting

Clinical, Morphological and Functional Aspects in Myocarditis.

Condition:   Myocarditis
Intervention:   Diagnostic Test: post-processing analysis of cardiac imaging (strain echocardiography)
Sponsors:   University of Messina;   Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy;   Humanitas Hospital, Italy;   Vannini Hospital Rome

Chinese Chronic Renal Insufficiency Study: Based on Smartphone Platform

Condition:   Chronic Kidney Diseases
Sponsors:   Limeng Chen;   First Hospital of China Medical University;   People's Hospital of Xinjiang Autonomous Region;   Fujian Provincial Hospital;   Shandong Provincial Qianfoshan Hospital;   First Affiliated Hospital Xi'an Jiaotong University;   Seventh Affiliated Hospital of Sun Yat-sen University;   People's Hospital of Ningxia Hui Autonomous Region
Not yet recruiting

Effect of Exercise and Respiratory Therapy on Right Ventricular Function in Severe Pulmonary Hypertension

Condition:   Pulmonary Hypertension
Intervention:   Other: Exercise and respiratory therapy
Sponsor:   Heidelberg University

Blood PREssure Augmentation in Large-vessel Occlusion Stroke Study

Conditions:   Ischemic Stroke;   Blood Pressure
Interventions:   Drug: Phenylephrine;   Drug: Norepinephrine
Sponsor:   Yale University
Not yet recruiting

Bariatric Surgery for the Reduction of cArdioVascular Events Feasibility Trial

Conditions:   Obesity, Morbid;   Cardiovascular Diseases
Intervention:   Procedure: Bariatric surgery
Sponsors:   Hamilton Health Sciences Corporation;   Population Health Research Institute;   St. Joseph's Healthcare Hamilton
Not yet recruiting

Clinical Usefulness of Virtual Antiarrhythmic Drug Test in Patients With Recurred AF After Catheter Ablation(CUVIA-AF3)

Condition:   Atrial Fibrillation
Interventions:   Drug: Virtual AAD TEST group;   Drug: Empirical AAD group
Sponsor:   Yonsei University
Not yet recruiting

COlchicine in Cardiac Surgery

Conditions:   Colchicine Adverse Reaction;   Atrial Fibrillation New Onset
Interventions:   Drug: Colchicine;   Drug: Placebo
Sponsor:   Bakulev Scientific Center of Cardiovascular Surgery

Safety and Efficacy of the SETA LATECBA Stent Graft for EVAR in Subjects With AAA

Condition:   Abdominal Aortic Aneurysm
Intervention:   Device: SETA LATECBA Stent Grafts
Sponsor:   Latecba S.A.

Paced Dyssynchrony and Myocardial Perfusion IN apiCal Hcm

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Other: Asynchronous dual chamber pacing (DOO) with paced ventricular activation;   Other: Asynchronous atrial pacing (AOO) with intrinsic ventricular activation
Sponsor:   Barts & The London NHS Trust
Not yet recruiting