Heart Attack

Clinical Trial Finder

Many patients with heart disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Association of Air Quality and Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:   Other: air pollution
Sponsor:   Medical University of Graz
Active, not recruiting - verified August 2016

Diagnosis of Fabry Disease: Impact of an Educational Brochure Intended for Cardiologist

Condition:   Cardiomyopathies
Intervention:  
Sponsor:   University Hospital, Caen
Recruiting - verified August 2016

Instantaneous Wave-Free Ratio and Fractional Flow Reserve for the Assessment of Non Culprit Lesions in Patients With ST-segment Elevation Myocardial Infarction

Condition:   ST Segment Elevation Myocardial Infarction
Intervention:   Other: FFR and iFR
Sponsor:   Azienda Ospedaliera San Camillo Forlanini
Recruiting - verified August 2016

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D)

Condition:   Anaemia
Interventions:   Drug: Daprodustat;   Drug: rhEPO;   Drug: Placebo;   Drug: Iron therapy
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified August 2016

Variations of High Sensitivity Troponin T in Neonates

Condition:   Newborn; Newborn, Transient
Intervention:   Biological: Troponin T blood level
Sponsor:   Centre Hospitalier René Dubos
Not yet recruiting - verified August 2016

High Intensity Aerobic Interval Training With Mediterranean Diet Recommendations in Post-Myocardial Infarct Patients

Condition:   Myocardial Infarction
Interventions:   Other: HIGH VOLUME (HV) Supervised exercise;   Other: Mediterranean Diet Recommendations;   Other: Physical Activity Recommendations;   Other: LOW VOLUME (LW) Supervised exercise
Sponsors:   Basque Country University;   HOSPITAL SANTIAGO APOSTOL. MIRANDA DE EBRO. BURGOS. SPAIN
Enrolling by invitation - verified August 2016

Extra Corporeal Membrane Oxygenation in the Acute Respiratory Distress Syndrome: Utility of a Biomarker to Assess the Membrane Efficiency in Improving Oxygenation

Condition:   Extra Corporel Membrane Oxygenation and Mciroparticles
Intervention:   Other: Blood draw
Sponsor:   Assistance Publique Hopitaux De Marseille
Active, not recruiting - verified August 2016

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Non-Dialysis (ASCEND-ND)

Condition:   Anaemia
Interventions:   Drug: Daprodustat;   Drug: Darbepoetin alfa;   Drug: Placebo;   Drug: Iron Therapy
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified August 2016

Leukocytes and Perioperative Cardio Vascular Events

Condition:   Elective Non-cardiac Surgery
Intervention:  
Sponsor:   University Hospital Heidelberg
Not yet recruiting - verified August 2016

Postconditioning by Cyclosporin A in Pulmonary Transplantation

Condition:   Lung Transplantation
Interventions:   Drug: Cyclosporine A;   Drug: Placebo
Sponsor:   Hospices Civils de Lyon
Not yet recruiting - verified August 2016

China PEACE 5p-HF Study

Condition:   Heart Failure
Intervention:   Other: Observational study
Sponsor:   China National Center for Cardiovascular Diseases
Not yet recruiting - verified August 2016

Validation of Chinese Version Appropriate Use Criteria for Coronary Revascularization

Conditions:   Appropriate Use Criteria;   Coronary Revascularization
Intervention:  
Sponsor:   China National Center for Cardiovascular Diseases
Recruiting - verified August 2016

Ffr-gUidance for compLete Non-cuLprit REVASCularization

Conditions:   Coronary Artery Disease;   ST-elevation Myocardial Infarction
Interventions:   Procedure: FFR Treatment Arm;   Other: Conservative Treatment Arm
Sponsors:   Felix Bohm;   Uppsala University;   Swedish Medical Research Council;   Swedish Heart Lung Foundation;   St. Jude Medical;   Boston Scientific Corporation
Recruiting - verified August 2016

Changes in Adiponectin and Cardiovascular Disease Risk Factors in Overweight Patients

Conditions:   Exercise;   Cardiac Myosins;   Patients
Interventions:   Other: Experimental;   Other: Control
Sponsor:   University of Isfahan
Completed - verified August 2016

Stem Cells Therapy in Advanced Heart Failure

Condition:   Congestive Heart Failure
Intervention:   Drug: stem cells infusion
Sponsor:   Second University of Naples
Completed - verified August 2016

The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock Patients

Condition:   Cardiogenic Shock
Interventions:   Procedure: Simultaneous RRT;   Procedure: Standard care
Sponsor:   Beijing Anzhen Hospital
Recruiting - verified August 2016

Study on the Effect of Influenza Vaccination After Heart Attack on Future Cardiovascular Prognosis

Conditions:   Myocardial Infarction;   Influenza, Human;   Influenza Vaccines;   Heart Failure;   Stroke
Interventions:   Biological: Influenza vaccine;   Biological: Placebo
Sponsors:   Ole Frobert, MD, PhD;   Swedish Heart Lung Foundation;   Sanofi Pasteur, a Sanofi Company;   Uppsala University;   Lytics
Not yet recruiting - verified August 2016

Effect of Testosterone Replacement on Exercise Capacity in Hypogonadal Men After a Recent Myocardial Infarction

Conditions:   Hypogonadism;   Acute Myocardial Infarction: Rehabilitation Phase
Interventions:   Drug: Testosterone;   Drug: Normal Saline
Sponsor:   Texas Tech University Health Sciences Center
Recruiting - verified August 2016

INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart Failure

Conditions:   Heart Failure;   Myocardial Infarction
Interventions:   Biological: High Dose Trivalent Influenza Vaccine;   Biological: Standard Dose Quadrivalent Influenza Vaccine
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   University of Wisconsin, Madison;   University of Toronto;   Boston VA Research Institute, Inc.;   Patient-Centered Outcomes Research Institute
Recruiting - verified August 2016

Reduced Immunogenicity Mesothelin-Targeted Immunotoxin LMB-100 in People With Malignant Mesothelioma

Condition:   Mesothelioma
Intervention:   Drug: LMB-100
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified June 2016

Comparison of 2 Hemostasis Techniques After Transradial Coronary

Condition:   Coronary Artery Disease With Myocardial Infarction
Interventions:   Device: Standardized compressive dressing;   Device: Hemostasis with TerumoBand®
Sponsor:   Hospital de Clinicas de Porto Alegre
Recruiting - verified August 2016

Anticoagulation Alone Versus Anticoagulation and Aspirin Following Transcatheter Aortic Valve Interventions (1:1)

Condition:   Transcatheter Aortic Valve Replacement
Interventions:   Drug: AVK;   Drug: Aspirin
Sponsors:   Centre Hospitalier Universitaire de Nīmes;   Medtronic
Not yet recruiting - verified August 2016

A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL_112;   Other: Placebo
Sponsor:   CSL Behring
Recruiting - verified August 2016

Safety and Efficacy Study of a Protease Activated Receptor-4 Antagonist Being Tested to Reduce the Chances of Having Additional Strokes or "Mini Strokes"

Condition:   Thrombosis
Interventions:   Drug: BMS-986141;   Drug: Aspirin;   Other: Placebo
Sponsor:   Bristol-Myers Squibb
Recruiting - verified July 2016

Ticagrelor Versus Clopidogrel in Carotid Artery Stenting

Condition:   Carotid Artery Stenosis
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel;   Drug: Aspirin
Sponsor:   University Hospital, Basel, Switzerland
Not yet recruiting - verified August 2016

A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease

Condition:   Prostate Cancer
Interventions:   Drug: Degarelix;   Drug: Leuprolide
Sponsors:   Ferring Pharmaceuticals;   Memorial Sloan Kettering Cancer Center;   Duke Clinical Research Institute
Recruiting - verified August 2016

A Prospective Cohort Study of Aged People for Chronic Diseases

Conditions:   Aging;   Sarcopenia
Intervention:  
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified August 2016

Which Platelet Function Test Best Reflects the In Vivo Plasma Concentrations of Ticagrelor and Its Active Metabolite?

Conditions:   Infarction;   Myocardial Infarction;   Cardiovascular Diseases;   Heart Diseases;   Ischemia;   Myocardial Ischemia;   Necrosis;   Pathologic Processes;   Vascular Diseases
Intervention:  
Sponsor:   Collegium Medicum w Bydgoszczy
Completed - verified August 2016

Nesiritide in Uncontrolled Hypertension

Condition:   Hypertension
Interventions:   Drug: Nesiritide;   Drug: Placebo
Sponsors:   Oslo University Hospital;   University of Oslo;   University Hospital, Akershus
Recruiting - verified August 2016

Aiming Towards Evidence Based Interpretation of Cardiac Biomarkers in Patients Presenting With Chest Pain

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   Haukeland University Hospital;   Helse Stavanger HF
Recruiting - verified August 2016

Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study

Conditions:   Vascular Inflammation;   Atherosclerotic Cardiovascular Disease
Interventions:   Drug: Low dose methotrexate;   Drug: Placebo
Sponsors:   Icahn School of Medicine at Mount Sinai;   Brigham and Women's Hospital;   Massachusetts General Hospital;   St. Michael's Hospital, Toronto;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

The Peregrine Post-Market Study for the Treatment of Hypertension

Condition:   Hypertension
Intervention:   Device: Peregrine System Infusion Catheter
Sponsor:   Ablative Solutions, Inc.
Recruiting - verified August 2016

Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes

Condition:   Transcatheter Aortic Valve Replacement
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Acetylsalicylic acid;   Drug: Clopidogrel
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified August 2016

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified August 2016

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified August 2016

GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Type IV Thoracoabdominal Aortic Aneurysms Involving the Visceral Branch Vessels

Condition:   Thoracoabdominal Aortic Aneurysm
Intervention:   Device: GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis
Sponsor:   W.L.Gore & Associates
Active, not recruiting - verified August 2016

Special Drug Use Investigation of Xarelto for Venous Thromboembolism (VTE)

Condition:   Venous Thromboembolism
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified August 2016

Preventive aBlation of vEntricular tachycaRdia in Patients With myocardiaL INfarction

Condition:   Ventricular Tachycardia
Intervention:   Procedure: VT ablation
Sponsor:   Biotronik SE & Co. KG
Recruiting - verified July 2016

The Use of Aging Biomarkers to Predict Adverse Outcomes After Cardiac Surgery

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   HealthSpan Dx;   Duke University
Recruiting - verified August 2016

Impact of Daylight on Patients With Acute Myocardial Infarction

Conditions:   Coronary Arteriosclerosis;   Myocardial Infarction
Interventions:   Other: Day Light;   Other: Room Light
Sponsor:   University of Colorado, Denver
Recruiting - verified August 2016

Biomarkers and Cardiac MRI as Early Indicators of Cardiac Exposure Following Breast Radiotherapy

Condition:   Breast Cancer
Interventions:   Procedure: Research Cardiac MRI;   Procedure: Biomarkers
Sponsors:   Henry Ford Health System;   University of Michigan Cancer Center
Recruiting - verified August 2016

Coronary InterventionS in HIgh-Risk PatiEnts Using a Novel Percutaneous Left Ventricular Support Device (SHIELD II)

Condition:   Coronary Artery Disease
Interventions:   Device: HeartMate PHP;   Device: Abiomed Impella® Recover® LP 2.5
Sponsors:   Thoratec Corporation;   St. Jude Medical
Recruiting - verified August 2016

6-month Intracoronary Optical Coherence Tomography (OCT) Evaluation of Three New Generation Drug Eluting Stent

Condition:   Recurrent Angina After Coronary Stent Placement
Intervention:   Device: optical coherence tomography at 6 months
Sponsor:   Azienda Ospedaliero-Universitaria Careggi
Completed - verified August 2016

Short-Term Application of Tocilizumab Following Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Drug: Tocilizumab;   Drug: Placebo
Sponsor:   Keesler Air Force Base Medical Center
Recruiting - verified August 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2016

Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery

Conditions:   Intraoperative Complication;   Malignant Female Reproductive System Neoplasm;   Pain
Interventions:   Drug: Epidural analgesia;   Other: Intraoperative Complication Management and Prevention;   Procedure: Pain Therapy
Sponsors:   University of Wisconsin, Madison;   National Cancer Institute (NCI)
Recruiting - verified August 2016

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study

Condition:   Cost Sharing, Acute Coronary Syndrome,
Intervention:   Other: Study voucher card
Sponsors:   AstraZeneca;   Duke Clinical Research Institute
Recruiting - verified August 2016

The Health Impact of High Intensity Exercise Training With Intervals During Cardiac Rehabilitation

Conditions:   Heart Disease;   Heart Attacks
Interventions:   Other: High intensity interval training (HIIT);   Other: Standard care
Sponsors:   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Edge Hill University
Completed - verified August 2016

Evaluation of Myocardial Viability : Dual Energy Cardiac CT vs. Cardiac MRI

Condition:   Myocardial Infarction
Intervention:   Radiation: second propeller arm scanner
Sponsor:   University Hospital, Rouen
Recruiting - verified August 2016

Feasability of Collaborative Care in the Secondary Prevention of Coronary Heart Disease

Condition:   Coronary Heart Disease
Intervention:   Behavioral: collaborative care CHD
Sponsors:   University of Göttingen;   German Centre for Cardiovascular Research (DZHK)
Recruiting - verified August 2016

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified August 2016

Ticagrelor in Patients With ST Elevation Myocardial Infarction Treated With Pharmacological Thrombolysis

Conditions:   Acute ST Segment Elevation Myocardial Infarction;   Thrombolysis in Myocardial Infarction Flow
Interventions:   Drug: Ticagrelor 180 mg;   Drug: Clopidogrel
Sponsor:   Hospital do Coracao
Recruiting - verified August 2016

A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction

Conditions:   Heart Attack;   NSTEMI
Interventions:   Biological: AMI MultiStem cells;   Other: Sham
Sponsors:   Athersys, Inc;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

Thoratec Corporation HeartMate PHP™ Cardiogenic Shock Trial

Condition:   Cardiogenic Shock
Intervention:   Device: HeartMate PHP
Sponsors:   Thoratec Corporation;   St. Jude Medical
Recruiting - verified August 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified August 2016

Novel Biomarkers for Risk Prediction of Contrast-Induced Acute Kidney Injury Post Coronary Angiography

Conditions:   Acute Kidney Injury;   Renal Insufficiency;   Kidney Diseases
Intervention:  
Sponsors:   HealthSpan Dx;   University of North Carolina, Chapel Hill
Recruiting - verified August 2016

BIOFLOW-III UK Satellite Registry

Condition:   Coronary Artery Diseases
Intervention:   Device: Orsiro
Sponsor:   Biotronik UK Ltd.
Recruiting - verified August 2016

A Trial of Low-dose Adjunctive alTeplase During prIMary PCI

Condition:   Myocardial Infarction
Interventions:   Drug: Alteplase;   Other: Placebo
Sponsors:   NHS Greater Glasgow and Clyde;   University of Glasgow;   National Institute for Health Research, United Kingdom
Recruiting - verified August 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

MOMENTUM 3 IDE Clinical Study Protocol

Condition:   Advanced Refractory Left Ventricular Heart Failure
Interventions:   Device: HeartMate 3 LVAS;   Device: HeartMate II LVAS
Sponsors:   Thoratec Corporation;   St. Jude Medical
Active, not recruiting - verified August 2016

Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.

Condition:   Acute Coronary Syndrome
Interventions:   Drug: MEOPA and paracetamol;   Drug: Morphine
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2016

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified August 2016

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Placebo
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified August 2016

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

The German Patient Blood Management Network

Condition:   Clinical Safety of a PBM Program
Intervention:  
Sponsors:   Johann Wolfgang Goethe University Hospital;   Vifor Pharma;   B. Braun Melsungen AG;   CSL Behring;   Fresenius Kabi
Recruiting - verified August 2016

Comparison of Antithrombotic Treatments After Aortic Valve Replacement. Rivaroxaban: A New Antithrombotic Treatment for Patients With Mechanical Prosthetic Aortic Heart Valve.

Conditions:   Aortic Valve Disease;   Heart Valve Prosthesis Implantation;   Anticoagulants
Intervention:   Drug: Rivaroxaban
Sponsor:   University Hospital Inselspital, Berne
Suspended - verified August 2016

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

Conditions:   Cardiomyopathy;   Coronary Artery Disease;   Congestive Heart Failure;   Myocardial Infarction
Interventions:   Device: Implantable Cardioverter Defibrillator;   Other: Optimal Medical Therapy
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury

Condition:   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   University of Edinburgh;   AstraZeneca
Recruiting - verified July 2016

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   Cleveland Clinic Coordinating Center for Clinical Research (C5R);   Quintiles, Inc.
Recruiting - verified August 2016

Sequential Expansion of Comparative Effectiveness of Anticoagulants

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

Understanding the Exercise-Hypertension Paradox

Condition:   Hypertension
Interventions:   Dietary Supplement: Oral Antioxidant;   Other: Exercise rehabilitation
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified August 2016

CD-NP (Cenderitide) Therapy for the Preservation of Left Ventricular Function

Condition:   ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Intervention:   Drug: CD-NP
Sponsor:   Mayo Clinic
Recruiting - verified August 2016

Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography

Conditions:   Atherosclerosis;   Stroke;   Transient Ischemic Attack;   Chronic Stable Angina;   Acute Coronary Syndrome
Intervention:  
Sponsor:   University of Cambridge
Completed - verified August 2016

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

Conditions:   Ischemic Stroke;   Atrial Fibrillation;   Transient Ischemic Attacks;   Transient Cerebrovascular Events;   Thrombotic Stroke;   Stroke of Basilar Artery;   Cardioembolic Stroke
Intervention:   Other: Biomarker blood draw
Sponsor:   Ischemia Care LLC
Recruiting - verified August 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified August 2016

Interleukin-1 (IL-1) Blockade in Acute Myocardial Infarction (VCU-ART3)

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Anakinra 100 mg;   Drug: Anakinra 100 mg;   Drug: Placebo
Sponsors:   Virginia Commonwealth University;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ ABSORB CHINA Randomized Controlled Trial (RCT)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: XIENCE V EECSS;   Device: Absorb BVS System
Sponsor:   Abbott Vascular
Active, not recruiting - verified August 2016

Epidemiology and Prognostic of the Acute Heart Failure

Conditions:   Decompensated Chronic Heart Failure;   Heart Failure NYHA Class III;   Acute Pulmonary Edema;   Cardiogenic Shock;   Heart Failure NYHA Class IV
Intervention:  
Sponsor:   Central Hospital, Nancy, France
Active, not recruiting - verified August 2016

Intensive Prevention Program After Myocardial Infarction

Conditions:   Myocardial Infarction.;   Prevention Harmful Effects.
Interventions:   Behavioral: Intensive Prevention Program;   Other: Standard medical and interventional therapy
Sponsors:   Herzzentrum Bremen;   Oldenburger Forschungs- und Entwicklungsinstitut für Informatik (OFFIS).
Active, not recruiting - verified August 2016

Interleukin-1 Blockade With Canakinumab to Improve Exercise Capacity in Patients With Chronic Systolic Heart Failure and Elevated High Sensitivity C-reactive Protein (Hs-CRP)

Conditions:   Prior Acute Myocardial Infarction;   Evidence of Systemic Inflammation (C Reactive Protein Plasma >2 mg/l);   Reduced Left Ventricle Ejection Fraction (<50%);   Symptoms of Heart Failure (NYHA Class II-III)
Interventions:   Other: Cardiopulmonary exercise test;   Other: Echocardiogram
Sponsors:   Virginia Commonwealth University;   Novartis Pharmaceuticals
Active, not recruiting - verified August 2016

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified August 2016

BIOFLOW-III Israel Satellite Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Diabetes Mellitus Type 1 or 2
Intervention:  
Sponsor:   BIOTRONIK Israel
Completed - verified August 2016

BIOFLOW-III Hungary Satellite Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:  
Sponsor:   Biotronik Hungária Kft.
Active, not recruiting - verified August 2016

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified August 2016

Antibody Treatment for Advanced Celiac Disease

Conditions:   Celiac Disease;   Celiac Sprue;   Gluten Enteropathy;   Gluten-Sensitive Enteropathy
Intervention:   Biological: Hu-Mik- Beta-1
Sponsors:   National Cancer Institute (NCI);   Mayo Clinic
Completed - verified August 2016

Angiogenesis and Fibrosis in Myocardial Infarction

Conditions:   Myocardial Infarction;   Fibrosis;   Neovascularization, Pathologic
Interventions:   Procedure: Cardiac MRI scan;   Radiation: CT-PET scan;   Radiation: CT-coronary angiogram
Sponsor:   University of Edinburgh
Completed - verified March 2015

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified August 2016

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified August 2016

Beta Blocker Therapy in Moderate to Severe COPD

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Biological: Carvedilol;   Biological: Bisoprolol;   Biological: Beclometasone/formoterol;   Biological: Tiotropium;   Biological: Beclometasone
Sponsors:   University of Dundee;   Tenovus Scotland
Completed - verified August 2016

Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

Conditions:   Aplastic Anemia;   Neutropenia;   Pancytopenia;   Anemia;   Thrombocytopenia
Interventions:   Drug: Eltrombopag;   Drug: Horse Anti-Thymocyte Globulin (ATG);   Drug: Cyclosporine A (CSA)
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

BIOFLOW-III All-comers Orsiro Safety and Performance Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:  
Sponsor:   Biotronik AG
Active, not recruiting - verified August 2016

Induction Chemo w/ABVD Followed by Brentuximab Vedotin Consolidation in Newly Diagnosed, Non-Bulky Stage I/II Hodgkin Lymphoma

Condition:   Hodgkin Lymphoma, Adult
Interventions:   Drug: Brentuximab vedotin;   Drug: ABVD
Sponsors:   UNC Lineberger Comprehensive Cancer Center;   Seattle Genetics, Inc.
Active, not recruiting - verified August 2016

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Completed - verified August 2016

Microcirculation In Acute Coronary Syndromes

Condition:   ST Elevation (STEMI) Myocardial Infarction
Interventions:   Drug: Rosuvastatin;   Drug: Simvastatin
Sponsors:   Helse Stavanger HF;   Helse Vest;   University Hospital of North Norway;   St. Olavs Hospital
Recruiting - verified August 2016

Impact of Coronary Images Used During Patient Education on Coronary Artery Disease and Subsequent Lifestyle Modifications. Is a Picture Really Worth a Thousand Words?

Condition:   Coronary Artery Disease
Intervention:   Behavioral: Impact of Coronary Images Used During Patient Education on Coronary Artery Disease and Subsequent Lifestyle Modifications
Sponsor:   University of Chicago
Recruiting - verified August 2016

International Survey of Acute Coronary Syndromes in Transitional Countries

Conditions:   Acute Coronary Syndrome;   Unstable Angina Pectoris;   Myocardial Infarction;   Coronary Disease
Intervention:  
Sponsor:   University of Bologna
Recruiting - verified August 2016

Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results - A Long Term Evaluation

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: liraglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Completed - verified August 2016

PREdisposition Genetical in Cardiac Insufficiency = Genetic Predisposition to Heart Failure

Condition:   ST Elevation (STEMI) Myocardial Infarction of Other Sites
Intervention:   Other: Cohort
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified August 2016

Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Comorbidities

Condition:   Cardiovascular Disease
Interventions:   Drug: Febuxostat;   Drug: Allopurinol
Sponsors:   Takeda;   Teijin America, Inc.
Active, not recruiting - verified August 2016

CANVAS - CANagliflozin cardioVascular Assessment Study

Conditions:   Diabetes Mellitus, Type 2;   Cardiovascular Diseases;   Risk Factors
Interventions:   Drug: Canagliflozin (JNJ-28431754);   Drug: Placebo
Sponsors:   Janssen Research & Development, LLC;   The George Institute for Global Health, Australia
Active, not recruiting - verified August 2016

Stress Testing and Cardiac Magnetic Resonance

Condition:   Coronary Disease
Intervention:   Drug: regadenoson
Sponsors:   University of Chicago;   Astellas Pharma Inc
Recruiting - verified August 2016

An Observational Study of Cholesterol in Coronary Arteries

Conditions:   Myocardial Infarction;   Angina;   Coronary Artery Disease;   Myocardial Ischemia
Intervention:   Device: Intravascular Near Infrared Spectroscopy
Sponsor:   InfraReDx
Active, not recruiting - verified August 2016

Triple Therapy in Patients on Oral Anticoagulation After Drug Eluting Stent Implantation

Conditions:   Coronary Artery Disease;   Atrial Fibrillation
Interventions:   Drug: aspirin;   Drug: clopidogrel;   Drug: oral anticoagulation
Sponsor:   Deutsches Herzzentrum Muenchen
Active, not recruiting - verified August 2014

Can Hypothermia be Incorporated Into Primary Angioplasty for Heart Attack?

Condition:   ST-Elevation Myocardial Infarction
Intervention:   Device: Life Recovery Systems ThermoSuit
Sponsor:   Life Recovery Systems
Not yet recruiting - verified August 2016

SDCC - Prospective Cohort Study of Chronic Renal Insufficiency

Condition:   Renal Insufficiency, Chronic
Intervention:  
Sponsors:   University of Pennsylvania;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Johns Hopkins University;   Case Western Reserve University;   University of Michigan;   University of Illinois at Chicago;   Tulane University;   Kaiser Permanente
Active, not recruiting - verified August 2016

Bone Marrow Transplant Studies for Safe and Effective Treatment of Leukemia

Conditions:   Graft vs Host Disease;   Hematologic Neoplasm;   Leukemia;   Multiple Myeloma;   Myelodysplastic Syndrome
Intervention:   Procedure: Allogeneic Bone Marrow Transplant
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 2016