Heart Attack

Clinical Trial Finder

Many patients with heart disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Platelet Inhibition After Pre-hospital Ticagrelor Using Fentanyl Compared to Morphine in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Fentanyl;   Drug: Morphine;   Drug: Ticagrelor;   Drug: Aspirin;   Drug: Unfractioned Heparin;   Procedure: Primary PCI
Sponsors:   Centre Hospitalier Universitaire Vaudois;   AstraZeneca
Not yet recruiting - verified August 2015

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Not yet recruiting - verified September 2015

Safety and Efficacy of Lotus Valve For TAVI In Patients With Severe Aortic Stenosis In Chinese Population

Condition:   Aortic Valve Stenosis
Intervention:   Device: Lotus Valve System
Sponsor:   Second Affiliated Hospital, School of Medicine, Zhejiang University
Not yet recruiting - verified August 2015

Central and Peripheral Blood Pressure in Stroke

Conditions:   Stroke, Acute;   Blood Pressure
Intervention:   Other: Blood pressure assessment
Sponsors:   Hampshire Hospitals NHS Foundation Trust;   The University of Winchester
Not yet recruiting - verified September 2015

Remote Ischemic Conditioning for Avoiding Recurrence of Symptomatic Intracranial Atherosclerotic Stenosis (sICAS)

Condition:   Intracranial Atherosclerosis
Interventions:   Device: Doctormate® (200mmHg);   Device: Doctormate® (60mmHg)
Sponsor:   Ji Xunming
Not yet recruiting - verified August 2015

Carotid Endarterectomy and Carotid Artery Stenting in Brazil

Condition:   Arterial Diseases, Carotid
Intervention:  
Sponsor:   University of Sao Paulo
Recruiting - verified August 2015

Attentional Capacity and Working Memory in Coronary Artery Disease Patients: Impact of the Presence of a Sleep Apnea Syndrome and Chronic Effects of Treatment With CPAP

Conditions:   Obstructive Sleep Apnea;   Acute Coronary Syndrome
Intervention:   Device: CPAP treatment
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting - verified August 2015

Effect of Simvastatin Withdrawal on Ocular Endothelial Function

Condition:   Healthy
Interventions:   Device: Dynamic Vessel Analyzer (DVA);   Device: Laser Doppler Velocimetry (LDV);   Drug: Simvastatin
Sponsor:   Medical University of Vienna
Not yet recruiting - verified August 2015

Contemporary Modalities in Treatment of Heart Failure

Condition:   Heart Failure
Intervention:  
Sponsor:   Silesian Centre for Heart Diseases
Recruiting - verified August 2015

Platelets Study: Influence of the Antiretroviral Treatment on the Platelet Physiology During HIV Infection

Condition:   Human Immunodeficiency Virus
Intervention:   Other: Blood samples
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Completed - verified August 2015

High Sensitivity Cardiac Troponin T in Patients With Atrial Fibrillation Admitted to an Emergency Department (ED)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   University Hospital Heidelberg
Completed - verified September 2015

Fructose and Ethnic Differences Study (FED Study)

Condition:   Healthy
Intervention:   Dietary Supplement: Dietary sugar
Sponsor:   King's College London
Completed - verified August 2015

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center (CPC), Denver, Colorado, USA
Recruiting - verified September 2015

PeRiodontal Treatment to Eliminate Minority InEquality and Rural Disparities in Stroke

Conditions:   Periodontal Disease;   Stroke;   TIA
Interventions:   Procedure: Intensive dental treatment;   Procedure: Standard dental treatment;   Drug: Arestin
Sponsors:   University of South Carolina;   University of North Carolina, Chapel Hill
Not yet recruiting - verified September 2015

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Recruiting - verified August 2015

Coronary InterventionS in HIgh-Risk PatiEnts Using a Novel Percutaneous Left Ventricular Support Device (SHIELD II)

Condition:   Coronary Artery Disease
Interventions:   Device: HeartMate PHP;   Device: Abiomed Impella® Recover® LP 2.5
Sponsor:   Thoratec Corporation
Recruiting - verified September 2015

A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction

Condition:   Heart Failure
Interventions:   Drug: BAY1142524;   Drug: BAY1142524;   Drug: BAY1142524;   Drug: BAY1142524;   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified August 2015

Impact of the Obstructive Sleep Apnea Syndrome (OSAS) on the Ventricular Remodeling After Acute Myocardial Infarction

Condition:   Recent Acute Myocardial Infarction
Interventions:   Other: Without Obstructive Sleep Apnea (syndrome);   Other: Mild or moderate Obstructive Sleep Apnea (syndrome);   Other: Severe Obstructive Sleep Apnea (syndrome);   Device: CPAP
Sponsor:   University Hospital, Montpellier
Recruiting - verified August 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural Medical University ;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified August 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified September 2015

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study

Condition:   Cost Sharing, Acute Coronary Syndrome,
Intervention:   Other: Study voucher card
Sponsors:   AstraZeneca;   Duke Clinical Research Institute
Recruiting - verified September 2015

Brilinta Taiwan Post Approval Safety Study

Condition:   Non ST-elevation Myocardial Infarction
Intervention:   Drug: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Sponsor:   AstraZeneca
Recruiting - verified August 2015

SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

Condition:   Internal Carotid Artery Stenosis
Intervention:   Device: sonolysis
Sponsors:   University Hospital Ostrava;   Military University Hospital, Prague;   Vitkovice Hospital, Ostrava;   Masaryk Hospital, Usti nad Labem;   České Budějovice Hospital;   University Hospital Hradec Kralove;   University Hospital Plzen, Plzen;   County Hospital Liberec, Liberec
Not yet recruiting - verified August 2015

The Health Impact of High Intensity Exercise Training With Intervals During Cardiac Rehabilitation

Conditions:   Heart Disease;   Heart Attacks
Interventions:   Other: High intensity interval training (HIIT);   Other: Standard care
Sponsors:   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Edge Hill University, UK
Recruiting - verified September 2015

Benefits of Exercise Training in Women With Ischemic Syndrome

Condition:   Microvascular Coronary Dysfunction
Intervention:   Behavioral: Exercise training
Sponsor:   Cedars-Sinai Medical Center
Not yet recruiting - verified August 2015

Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine

Condition:   Coronary Artery Disease
Interventions:   Drug: Methylnaltrexone;   Other: Placebo;   Drug: Morphine;   Drug: Ticagrelor
Sponsor:   University of Florida
Recruiting - verified September 2015

Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Colchimax®;   Drug: Conventional treatment
Sponsor:   University Hospital, Montpellier
Active, not recruiting - verified September 2015

Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults

Conditions:   HIV Infections;   Cardiovascular Diseases
Interventions:   Drug: Pitavastatin;   Drug: Placebo
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   National Heart, Lung, and Blood Institute (NHLBI);   Kowa Pharmaceuticals America, Inc.
Recruiting - verified August 2015

China PEACE II: Quality Improvement for Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Behavioral: Quality improvement strategies and tools;   Behavioral: Process optimization
Sponsor:   China National Center for Cardiovascular Diseases
Recruiting - verified August 2015

Stockholm Myocardial Infarction With Normal Coronaries (SMINC)-2 Study on Diagnosis Made by Cardiac MRI

Condition:   Myocardial Infarction
Intervention:   Procedure: CMR
Sponsors:   Karolinska Institutet;   Swedish Medical Research Council
Recruiting - verified August 2015

MGuard™ Prime Embolic Protection Stent in Patients With Acute ST Elevation Myocardial Infarction

Condition:   ST Elevation Myocardial Infarction
Intervention:   Device: MGuard™ Prime Embolic Protection Stent System
Sponsor:   InspireMD
Terminated - verified August 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Magnetic Resonance Imaging for Global Atherosclerosis Risk Assessment

Conditions:   Cardiovascular Disease;   Atherosclerosis
Interventions:   Other: MRI;   Other: PET/MRI;   Other: Laboratory blood test
Sponsor:   Cedars-Sinai Medical Center
Recruiting - verified August 2015

PLATINUM Diversity

Conditions:   Atherosclerosis;   Coronary Artery Disease
Intervention:   Device: Percutaneous coronary intervention (Promus PREMIER)
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified August 2015

Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVR

Condition:   Peripheral Artery Disease (PAD)
Interventions:   Drug: Ticagrelor;   Drug: Comparator
Sponsors:   AstraZeneca;   CPC Clinical Research
Recruiting - verified August 2015

Pharmacological Effects of Crushing Prasugrel in STEMI Patients

Condition:   Coronary Artery Disease
Intervention:   Drug: prasugrel
Sponsor:   University of Florida
Active, not recruiting - verified August 2015

Active Surveillance Research Program for the Assessment of the Safety and the Effectiveness of Linagliptin

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified August 2015

Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.

Condition:   Acute Coronary Syndrome
Interventions:   Drug: MEOPA and paracetamol;   Drug: Morphine
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2015

Telehealth Self-Management Program in Older Adults Living With Heart Failure in Health Disparity Communities

Condition:   Chronic Heart Failure
Interventions:   Device: Telehealth Self Management (TSM);   Other: Standard of Care
Sponsor:   North Shore Long Island Jewish Health System
Recruiting - verified August 2015

Canadian SCAD Study

Condition:   Spontaneous Coronary Artery Dissection
Intervention:  
Sponsors:   Cardiology Research UBC;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified August 2015

TandemHeart to Reduce Infarct Size (TRIS Trial)

Condition:   Acute Myocardial Infarction
Interventions:   Device: TandemHeart System;   Procedure: Percutaneous coronary intervention
Sponsor:   CardiacAssist, Inc.
Recruiting - verified May 2015

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified September 2015

Frontal Cognitive Control Functions Before and After Percutaneous Catheter Procedures in Treatment of Atrial Fibrillation

Conditions:   Neurobehavioral Manifestations;   Atrial Fibrillation
Intervention:  
Sponsor:   Tampere University Hospital
Recruiting - verified September 2015

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Losmapimod 7.5 mg twice daily;   Drug: Placebo twice daily
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Recruiting - verified August 2015

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL112;   Biological: Placebo
Sponsor:   CSL Behring
Recruiting - verified August 2015

Study of the Impact of Dairy Fat on Cardiovascular Health.

Condition:   Metabolic Syndrome
Interventions:   Other: Cheese diet;   Other: Butter diet;   Other: CHO diet;   Other: MUFA diet;   Other: PUFA diet
Sponsors:   Laval University;   Agriculture and Agri-Food Canada;   Dairy Farmers of Canada
Active, not recruiting - verified September 2015

Combined Bronchodilators in Chronic Obstructive Pulmonary Disease and the Risk of Adverse Cardio-pulmonary Events

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified August 2015

Sequential Expansion of Comparative Effectiveness of Anticoagulants

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2015

Elite Controller and ART-treated HIV+ Statin Versus ASA Treatment Intervention Study

Condition:   HIV Infection
Interventions:   Drug: Aspirin 81 mg daily;   Drug: Atorvastatin 40 mg daily
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified September 2014

Use of Abbott High Sensitivity Troponin I Assay In Acute Coronary Syndromes

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction;   Troponin
Intervention:  
Sponsors:   Minneapolis Medical Research Foundation;   Abbott Diagnostics Division;   Hennepin County Medical Center, Minneapolis
Active, not recruiting - verified August 2015

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)

Conditions:   Hypertension;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified August 2015

Understanding the Exercise-Hypertension Paradox

Condition:   Hypertension
Interventions:   Dietary Supplement: Oral Antioxidant;   Other: Exercise rehabilitation
Sponsor:   Department of Veterans Affairs
Recruiting - verified August 2015

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Ticagrelor 60 mg;   Drug: Ticagrelor placebo
Sponsor:   AstraZeneca
Recruiting - verified September 2015

[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]

Conditions:   Acute Ischaemic Stroke;   Transient Ischaemic Attack.
Interventions:   Drug: ticagrelor;   Drug: Acetylsalicylic acid (ASA)
Sponsor:   AstraZeneca
Recruiting - verified September 2015

Optimizing Antithrombotic Care in Patients With AtriaL fibrillatiON and Coronary stEnt (OAC-ALONE) Study

Conditions:   Atrial Fibrillation;   Coronary Artery Disease
Intervention:   Drug: OAC alone
Sponsors:   Satoshi Shizuta;   Research Institute for Production Development;   Daiichi Sankyo Co., Ltd.
Recruiting - verified August 2015

Colchicine Or Naproxen Treatment for ACute gouT

Condition:   Gout
Interventions:   Drug: Low-dose colchicine;   Drug: Naproxen
Sponsor:   Keele University
Recruiting - verified September 2015

First in Man Study of the DREAMS 2nd Generation Drug Eluting Absorbable Metal Scaffold (BIOSOLVE-II)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis
Intervention:   Device: Percutaneous Coronary Intervention (DREAMS) stenting
Sponsor:   Biotronik AG
Active, not recruiting - verified September 2015

Effect of Atorvastatin on Fractional Flow Reserve in Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Drug: Atorvastatin
Sponsors:   Keimyung University Dongsan Medical Center;   Seoul National University Hospital;   Ulsan University Hospital;   Inje University
Recruiting - verified August 2015

Comparison of the Biolimus A9-eluting Stent With the Zotarolimus -Eluting Stent in Multi-vessel PCI

Condition:   Multivessel Coronary Artery Disease
Intervention:   Procedure: Percutaneous Coronary Intervention
Sponsor:   Keimyung University Dongsan Medical Center
Recruiting - verified August 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified August 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Acenocoumarol
Sponsor:   Bayer
Recruiting - verified August 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Phenprocoumon
Sponsor:   Bayer
Recruiting - verified August 2015

GLORIA-AF Registry Program (Phase II/III)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2015

Resolute Integrity US Extended Length Sub-Study(RI-US XL)

Condition:   Coronary Artery Disease
Intervention:   Device: Resolute Integrity Stent
Sponsor:   Medtronic Vascular
Recruiting - verified September 2015

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified September 2015

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

Condition:   Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Withdrawn - verified September 2015

MGuard™ Prime Stent System Clinical Trial in Patients With Acute ST Elevation Myocardial Infarction

Condition:   ST Elevation Myocardial Infarction
Interventions:   Device: MGuard Prime;   Device: (BMS/DES)
Sponsor:   InspireMD
Terminated - verified August 2015

Long-Term rIsk, Clinical manaGement and Healthcare Resource Utilization of Stable CAD in Post MI Patients

Condition:   Stable Coronary Artery Disease (CAD), Myocardial Infarction
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified September 2015

OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA

Conditions:   Coronary Heart Disease;   Diabetes;   Vascular Lesions;   Chronic Total Occlusion of Coronary Artery;   Restenosis
Intervention:   Device: TAXUS™ Element long stent
Sponsors:   Centre Chirurgical Marie Lannelongue;   Cochin Hospital;   Centre Hospitalier de La Rochelle;   University Hospital, Limoges;   Hôpital de la Timone;   Centre Hospitalier Universitaire de Nice;   Centre Hospitalier de PAU;   Rangueil Hospital;   Central Hospital, Versailles
Recruiting - verified August 2015

Optical Frequency Domain Imaging (OFDI) Assessed Strut Coverage of New Terumo DES

Condition:   Coronary Artery Disease
Intervention:   Device: TCD-10023 drug eluting stent
Sponsor:   Terumo Europe N.V.
Active, not recruiting - verified September 2015

A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities

Condition:   Cardiovascular Disease, Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: aleglitazar
Sponsor:   Hoffmann-La Roche
Completed - verified September 2015

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2015

China PEACE-Prospective AMI Study

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   China National Center for Cardiovascular Diseases;   Ministry of Health, China
Completed - verified August 2015

Brazilian Cardioprotective Nutritional Program Trial

Condition:   Cardiovascular Diseases
Interventions:   Behavioral: BALANCE;   Behavioral: Cardioprotective diet
Sponsor:   Hospital do Coracao
Active, not recruiting - verified September 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

SAMURAI-NVAF Study: Anticoagulant Therapy for Japanese Stroke Patients With Nonvalvular Atrial Fibrillation (NVAF)

Conditions:   Stroke, Acute;   Atrial Fibrillation
Intervention:   Other: This is an observational study.
Sponsor:   Ministry of Health, Labour and Welfare, Japan
Active, not recruiting - verified August 2015

Left Atrial Appendage Occlusion Study III

Conditions:   Cardiac Surgery With Cardiopulmonary Bypass;   Atrial Fibrillation
Intervention:   Other: Left Atrial Appendage Occlusion
Sponsor:   Population Health Research Institute
Recruiting - verified August 2015

Prospective Study of End Stage Renal Disease Patients With Coronary Artery Disease Treated by Oral Nicorandil

Conditions:   Coronary Artery Disease;   End Stage Renal Disease
Intervention:   Drug: Nicorandil (15mg/day)
Sponsor:   Kumamoto University
Active, not recruiting - verified August 2015

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2015

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Recruiting - verified August 2015

Femoral Versus Radial Access for Primary PCI

Condition:   Myocardial Infarction
Intervention:   Procedure: Radial access site vs. Femoral Access site
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting - verified September 2015

Prospective Cohort With Incident Stroke

Condition:   Ischemic Stroke
Intervention:  
Sponsors:   Ludwig-Maximilians - University of Munich;   Charite University, Berlin, Germany
Recruiting - verified September 2015

A Study of RO4905417 in Patients With Non ST-Elevation Myocardial Infarction (Non-STEMI) Undergoing Percutaneous Coronary Intervention

Condition:   Myocardial Infarction
Interventions:   Procedure: Percutaneous Coronary Intervention (PCI);   Drug: RO4905417;   Drug: RO4905417;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified September 2015

A Study of RoActemra/Actemra (Tocilizumab) in Comparison to Etanercept in Patients With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Condition:   Cardiovascular Disease, Rheumatoid Arthritis
Interventions:   Drug: etanercept;   Drug: tocilizumab [RoActemra/Actemra]
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified September 2015

Atorvastatin for Preventing Occlusion and Restenosis After Intracranial Artery Stenting

Condition:   CVD
Intervention:   Drug: atorvastatin
Sponsor:   Jinling Hospital, China
Completed - verified September 2015

Exenatide Study of Cardiovascular Event Lowering Trial (EXSCEL): A Trial To Evaluate Cardiovascular Outcomes After Treatment With Exenatide Once Weekly In Patients With Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Exenatide Once Weekly;   Drug: Placebo
Sponsor:   AstraZeneca
Recruiting - verified September 2015

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified September 2015

The Enhanced Angiogenic Cell Therapy - Acute Myocardial Infarction Trial

Condition:   Anterior Wall Myocardial Infarction
Interventions:   Biological: Plasma-Lyte A and 25% Autologous Plasma;   Biological: Autologous EPCs;   Biological: Autologous EPCs Transfected with human eNOS
Sponsors:   Ottawa Hospital Research Institute;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified September 2015

Effects of Telmisartan on Ischemic Cardiovascular Events in High-risk Hypertensive Patients

Conditions:   Acute Myocardial Infarction;   Angina Pectoris;   Myocardial Ischemia;   Acute Coronary Syndrome;   Hypertension
Interventions:   Drug: Micardis (Telmisartan);   Drug: Blopress (Candesartan)
Sponsor:   Kyoto Prefectural University of Medicine
Terminated - verified September 2015

A Study of All-Cause Mortality and Cardiovascular Morbidity in CKD Patients on Dialysis and Those Not on Renal Replacement Therapy Receiving Mircera or Reference ESAs.

Condition:   Anemia
Interventions:   Drug: ESAs (darbepoetin alfa, epoetin alfa or epoetin beta);   Drug: methoxy polyethylene glycol-epoetin beta [Mircera];   Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified September 2015

Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina;   Acute Coronary Syndrome
Interventions:   Procedure: Coronary Computed Tomography Angiography;   Procedure: Stress Nuclear Myocardial Perfusion Imaging
Sponsors:   Montefiore Medical Center;   American Heart Association;   Albert Einstein College of Medicine of Yeshiva University
Completed - verified August 2015

Thiazolidinediones Or Sulphonylureas and Cardiovascular Accidents.Intervention Trial

Conditions:   Type 2 Diabetes Mellitus;   Cardiovascular Disease
Interventions:   Drug: add-on pioglitazone;   Drug: add-on sulphonylurea
Sponsors:   Italian Society of Diabetology;   Associazione Medici Diabetologi (AMD);   Associazione Nazionale Medici Cardiologi Ospedalieri
Active, not recruiting - verified August 2015

Left Ventricular Function Assessment After Acute Myocardial Infarction: Comparison Between Bi-, Three-dimensional and Cardiac Magnetic Resonance

Condition:   Acute Myocardial Infarction
Intervention:   Other: compare measurements of left ventricular volumes and LVEF (by Cardiac Magnetic Resonance and Echocardiography)
Sponsor:   Assistance Publique Hopitaux De Marseille
Completed - verified June 2008

Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

Conditions:   Lymphoma;   Leukemia;   Myeloproliferative Disorders;   Multiple Myleoma;   Myelodysplastic Syndrome
Interventions:   Drug: Rituximab;   Drug: Fludarabine;   Drug: Cyclosporine;   Drug: Etoposide;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Cyclophosphamide;   Biological: T-Rapa cell DLI;   Procedure: T cell DLI;   Drug: Prednisone;   Procedure: Allogeneic HSCT;   Drug: Filgrastim
Sponsor:   National Cancer Institute (NCI)
Suspended - verified September 2014

Effects of Disease Management on Development of End Stage Renal Disease in Type 2 Diabetic Patients With Nephropathy

Conditions:   Type 2 Diabetes Mellitus;   DM Nephropathy
Intervention:   Behavioral: Multidisciplinary team care
Sponsor:   Chinese University of Hong Kong
Completed - verified August 2015

Insulin Resistance Intervention After Stroke Trial

Conditions:   Stroke;   Myocardial Infarction;   Diabetes
Interventions:   Drug: pioglitazone;   Drug: placebo
Sponsors:   Yale University;   National Institute of Neurological Disorders and Stroke (NINDS);   Takeda Pharmaceuticals North America, Inc.
Active, not recruiting - verified August 2015

EARLY ACS: Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-segment Elevation Acute Coronary Syndrome (Study P03684AM2)(COMPLETED)

Conditions:   Myocardial Ischemia;   Acute Coronary Syndrome
Interventions:   Drug: Eptifibatide (Integrilin);   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Duke Clinical Research Institute
Completed - verified September 2015

Campath-1H and EPOCH to Treat Non-Hodgkin's T- and NK-Cell Lymphomas

Conditions:   Lymphoma, T-Cell;   Lymphoma, Extranodal NK-T-Cell
Interventions:   Biological: Alemtuzumab (Campath);   Drug: EPOCH
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified August 2015

Bone Marrow Transplant Studies for Safe and Effective Treatment of Leukemia

Conditions:   Graft vs Host Disease;   Hematologic Neoplasm;   Leukemia;   Multiple Myeloma;   Myelodysplastic Syndrome
Intervention:   Procedure: Allogeneic Bone Marrow Transplant
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 2015

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