Heart Attack

Clinical Trial Finder

Many patients with heart disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction

Condition:   Heart Failure
Interventions:   Drug: BAY1142524;   Drug: BAY1142524;   Drug: BAY1142524;   Drug: BAY1142524;   Drug: Placebo
Sponsor:   Bayer
Not yet recruiting - verified May 2015

Factors Associated With Perioperative Outcomes in Non-emergency Surgery

Conditions:   Stroke;   Acute Coronary Syndrome;   Pneumonia
Intervention:   Other: stroke or myocardial infarction or pneumonia
Sponsors:   University of Nottingham;   University of Wisconsin, Madison
Completed - verified May 2015

Effects of Nicorandil on Cardiac Infarct Size in Patients With ST-segment Elevation Acute Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Drug: Nicorandil
Sponsors:   Pusan National University Hospital;   JW Pharmaceutical
Recruiting - verified May 2015

Comparison of Anticoagulation for All-comers Undergoing Percutaneous Coronary Revascularization Trial

Condition:   Percutaneous Coronary Intervention
Interventions:   Drug: Bivalirudin;   Drug: Unfractionated heparin
Sponsor:   Kaiser Permanente
Recruiting - verified May 2015

SLEep APnea Screening Using Mobile Ambulatory Recorders After TIA/Stroke

Conditions:   Stroke;   Transient Ischemic Attack;   Obstructive Sleep Apnea
Intervention:   Device: Portable sleep monitor (ApneaLink Air)
Sponsors:   Sunnybrook Health Sciences Centre;   St. Michael's Hospital, Toronto
Not yet recruiting - verified May 2015

Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome

Conditions:   Cardiac Death;   Hemorrhage;   Cerebrovascular Accident;   Myocardial Infarction
Interventions:   Device: BES (biodegradable polymer biolimus-eluting stent);   Drug: Prasugel;   Drug: Clopidogrel
Sponsor:   Chonnam National University Hospital
Recruiting - verified May 2015

A Prospective, Single-Blinded, Multi-Center, Randomized, Controlled, Registered Clinical Trial on the Efficacy and Safety of Sirolimus-Eluting Stent (MiStent® System) in the Treatment of Patients With Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Device: MiStentTM;   Device: TIVOLI
Sponsors:   Micell Technologies;   Hefei Life Science Medical Instruments Co. Ltd.;   Giant Med-Pharma Services Inc.;   CCRF Consulting Co., Ltd.
Not yet recruiting - verified May 2015

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Recruiting - verified May 2015

Effects of Ivabradine in Patients With Stable Coronary Artery Disease Without Clinical Heart Failure

Condition:   Coronary Artery Disease.
Interventions:   Drug: Ivabradine;   Drug: Placebo
Sponsor:   Servier
Completed - verified May 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified May 2015

Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis

Condition:   Asymptomatic Severe Aortic Stenosis
Intervention:   Procedure: surgical aortic valve replacement
Sponsor:   Clinical Centre of Serbia
Not yet recruiting - verified May 2015

A Observational Study to Evaluate the Incidence of and Risk Factors for Vascular Occlusive Events Associated With Iclusig®

Condition:   Myeloid Leukemia, Chronic, Chronic-Phase
Intervention:  
Sponsors:   Ariad Pharmaceuticals;   United BioSource Corporation
Not yet recruiting - verified May 2015

COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Exenatide;   Other: Remote Ischemic Conditioning (RIC)
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Not yet recruiting - verified March 2015

CRIC-Visceral Adiposity and Physical Fitness in Chronic Kidney Disease

Conditions:   Renal Insufficiency, Chronic;   Obesity
Intervention:  
Sponsors:   The Cleveland Clinic;   University of Pennsylvania;   Case Western Reserve University;   University of Michigan;   University of Illinois at Chicago;   University of Maryland;   MetroHealth Medical Center
Recruiting - verified April 2015

Brilinta Taiwan Post Approval Safety Study

Condition:   Non ST-elevation Myocardial Infarction
Intervention:   Drug: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults

Conditions:   HIV Infections;   Cardiovascular Diseases
Interventions:   Drug: Pitavastatin;   Drug: Placebo
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   National Heart, Lung, and Blood Institute (NHLBI);   Kowa Pharmaceuticals America, Inc.
Recruiting - verified May 2015

Role of PPAR-y Anonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)

Condition:   Systemic Lupus Erthematosus
Interventions:   Radiation: PET/CT;   Drug: Pioglitazone;   Procedure: Vascular function studies
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified December 2014

The Use of Texting Messaging to Improve the Hospital-to-community Transition Period in Cardiovascular Disease Patients

Conditions:   Cardiovascular Disease;   Acute Coronary Syndrome
Intervention:   Behavioral: Txt2Prevent
Sponsors:   Simon Fraser University;   Providence Health & Services;   University of British Columbia;   McMaster University;   Canadian Institutes of Health Research  (CIHR)
Not yet recruiting - verified May 2015

Human Umbilical Cord Stroma MSC in Myocardial Infarction

Conditions:   Chronic Ischemic Cardiomyopathy;   Coronary Artery Bypass Surgery
Intervention:   Biological: stem cell transplantation
Sponsors:   Ankara University;   Hacettepe University;   Turkiye Yuksek Ihtisas Education and Research Hospital;   ATIGEN-CELL;   Dr. Sami Ulus Children's Hospital;   Yildirim Beyazit University
Recruiting - verified May 2015

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified May 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Prediction of Recurrent Events With 18F-Fluoride

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:  
Sponsors:   University of Edinburgh;   NHS Lothian;   Oxford University Hospitals NHS Trust;   Central Manchester University Hospitals NHS Foundation Trust;   NHS Grampian;   Wellcome Trust
Not yet recruiting - verified May 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Rapid Assessment of Potential Ischaemic Heart Disease With CTCA

Condition:   Acute Coronary Syndrome
Intervention:   Radiation: CT Coronary Angiogram
Sponsors:   University of Edinburgh;   NHS Lothian
Recruiting - verified May 2015

Eliminate Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Drug: Atorvastatin
Sponsors:   University Health Network, Toronto;   Advanced Medical Research Institute of Canada
Recruiting - verified May 2015

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2015

Cerebral Oxygenation in Septic Patients Using Vasopressors - the Conscious Study

Condition:   Septic Shock
Intervention:  
Sponsor:   Karl-Andre Wian
Recruiting - verified May 2015

HeartMate III™ IDE Clinical Study Protocol

Condition:   Advanced Refractory Left Ventricular Heart Failure
Interventions:   Device: HeartMate III LVAS;   Device: HeartMate II LVAS
Sponsor:   Thoratec Corporation
Recruiting - verified May 2015

TandemHeart to Reduce Infarct Size (TRIS Trial)

Condition:   Acute Myocardial Infarction
Interventions:   Device: TandemHeart System;   Procedure: Percutaneous coronary intervention
Sponsor:   CardiacAssist, Inc.
Recruiting - verified May 2015

Increasing Cardiac Rehabilitation Participation Among Medicaid Enrollees

Condition:   Coronary Artery Disease
Intervention:   Behavioral: Financial incentives
Sponsors:   University of Vermont;   National Institute of General Medical Sciences (NIGMS)
Recruiting - verified May 2015

DLBS1033 for Acute NSTEMI Without Early Coronary Revascularization

Condition:   Acute Non-ST Elevation Myocardial Infarction
Interventions:   Drug: DLBS1033;   Drug: Placebo
Sponsor:   Dexa Medica Group
Not yet recruiting - verified May 2015

Safety and Tolerability of a Modified Vaccinia Ankara (MVA)-Based Vaccine Modified to Express Brachyury and T-cell Costimulatory Molecules (MVA-Brachyury-TRICOM)

Conditions:   Lung Cancer;   Breast Cancer;   Prostate Cancer;   Tumors (Others);   Ovarian Cancer
Intervention:   Biological: MVA-brachyury- TRICOM
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified May 2015

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL112;   Biological: Placebo
Sponsor:   CSL Behring
Recruiting - verified May 2015

Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects

Conditions:   Type 2 Diabetes;   Coronary Artery Disease
Intervention:  
Sponsors:   British Cardiac Research Trust;   Royal Free Hospital NHS Foundation Trust;   London North West Healthcare NHS Trust;   Barnet and Chase Farm Hospitals NHS Trust;   Diabetes and Obesity Research Network;   Lund University;   Health Diagnostic Laboratory, Inc.
Recruiting - verified May 2015

Cologne Register of Wearable Defibrillator (CRWD)

Conditions:   Myocardial Infarction;   Ventricular Dysfunction;   Myocarditis
Intervention:  
Sponsors:   University of Cologne;   Zoll Medical Corporation
Recruiting - verified May 2015

The GRAFT Study: Evaluation of Graft Function, Rejection and Cardiac Allograft Vasculopathy in First Heart Transplant Recipients.

Condition:   Heart Transplant Recipients
Interventions:   Procedure: OCT and coronary angiography;   Procedure: Right heart cat.;   Radiation: PET;   Procedure: Echocardiography;   Procedure: exercise test;   Other: blood samples
Sponsor:   Aarhus University Hospital Skejby
Recruiting - verified May 2015

Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism)

Conditions:   Pulmonary Embolism;   Thromboembolism;   Thrombosis;   Venous Thrombosis;   Venous Thromboembolism
Interventions:   Drug: BAY 59-7939;   Drug: BAY 59-7939;   Drug: ASA
Sponsor:   Bayer
Recruiting - verified May 2015

Transfusion Requirements in Cardiac Surgery III

Condition:   Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Interventions:   Other: Restrictive Transfusion Strategy;   Other: Liberal transfusion strategy
Sponsor:   St. Michael's Hospital, Toronto
Recruiting - verified May 2015

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified May 2015

A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk Factors

Conditions:   Cardiovascular Disease;   High Cardiovascular Risk;   Obesity;   Overweight;   Type 2 Diabetes
Interventions:   Drug: APD356-Lorcaserin hydrochloride;   Drug: Placebo
Sponsors:   Eisai Inc.;   Thrombolysis In Myocardial Infarction (TIMI) Academic Research Organization
Recruiting - verified May 2015

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Ticagrelor 90 mg;   Drug: Ticagrelor placebo
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Cardiovascular Outcomes Following Treatment With Ertugliflozin in Participants With Type 2 Diabetes Mellitus and Established Vascular Disease (MK-8835-004)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Recruiting - verified May 2015

Ticagrelor in Severe Community Acquired Pneumonia

Condition:   Community Acquired Pneumonia, Severe
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   Gordon Bernard;   AstraZeneca
Recruiting - verified May 2015

[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]

Conditions:   Acute Ischaemic Stroke;   Transient Ischaemic Attack.
Interventions:   Drug: ticagrelor;   Drug: Acetylsalicylic acid (ASA)
Sponsor:   AstraZeneca
Recruiting - verified May 2015

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2015

To Study the Safety and Clinical Outcomes of the Absorb Bioresorbable Vascular Scaffold (BVS) System in Patients With de Novo Lesions in Previously Untreated Vessels

Conditions:   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Intervention:   Device: Absorb BVS
Sponsor:   Abbott Vascular
Recruiting - verified May 2015

Exenatide for Myocardial Protection During Reperfusion Study

Condition:   Myocardial Infarction
Interventions:   Drug: Exenatide;   Drug: Placebo
Sponsors:   University Health Network, Toronto;   AstraZeneca
Recruiting - verified May 2015

Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Drug: Apixaban;   Drug: aspirin
Sponsors:   Population Health Research Institute;   Bristol-Myers Squibb;   Pfizer;   Medtronic
Recruiting - verified May 2015

Study of GSK1278863 to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm Repair

Condition:   Surgical Procedures
Interventions:   Drug: GSK1278863;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Active, not recruiting - verified April 2015

A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ ABSORB CHINA Randomized Controlled Trial (RCT)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: XIENCE V EECSS;   Device: ABSORB BVS System
Sponsor:   Abbott Vascular
Active, not recruiting - verified May 2015

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified May 2015

Determining the Effect of Abacavir on Platelet Activation

Conditions:   HIV;   Cardiovascular Disease
Intervention:   Drug: Abacavir
Sponsor:   Bayside Health
Completed - verified May 2015

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified May 2015

Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention

Condition:   Acute ST Segment Elevation Myocardial Infarction
Interventions:   Drug: NAC;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified October 2014

Non-interventional Local Study on Prescription Behavior of Anticoagulation Therapy in Secondary Stroke Prevention in Atrial Fibrillation Patients

Conditions:   Stroke,;   Embolism
Intervention:   Other: Rivaroxaban ( Xarelto, BAY59-7939)
Sponsor:   Bayer
Active, not recruiting - verified May 2015

Portuguese Study on The Evaluation of FFR Guided Treatment of Coronary Disease

Condition:   Coronary Artery Disease
Intervention:   Device: Fractional flow reserve (St. Jude Medical pressure-wire)
Sponsors:   Portuguese Society of Cardiology;   Portuguese Association of Interventional Cardiology;   St. Jude Medical
Completed - verified May 2015

Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Interventions:   Drug: N-acetyl cysteine;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified October 2014

A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: rivaroxaban 2.5 mg;   Drug: rivaroxaban 15 mg;   Drug: rivaroxaban 10 mg;   Drug: aspirin (ASA);   Drug: vitamin K antagonist (VKA);   Drug: clopidogrel;   Drug: prasugrel;   Drug: ticagrelor
Sponsors:   Janssen Scientific Affairs, LLC;   Bayer
Recruiting - verified May 2015

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Recruiting - verified May 2015

Permeability MRI in Cerebral Cavernous Malformations Type 1 in New Mexico: Effects of Statins

Conditions:   Cavernous Angioma, Familial;   Cerebral Cavernous Malformations;   Cerebral Cavernous Hemangioma
Intervention:   Drug: Simvastatin
Sponsors:   University of New Mexico;   National Institute of Neurological Disorders and Stroke (NINDS);   University of California, San Francisco
Recruiting - verified May 2015

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified May 2015

Does Tranexamic Acid Reduce the Need for Blood Transfusions in Patients Undergoing Hip Fracture Surgery?

Condition:   Hip Fracture
Intervention:   Drug: tranexamic acid
Sponsor:   Mayo Clinic
Active, not recruiting - verified May 2015

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab SAR236553 (REGN727)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Other: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified May 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders.

Condition:   Smoking Cessation
Interventions:   Drug: placebo;   Drug: varenicline tartrate;   Drug: bupropion hydrochloride;   Drug: Nicotine Replacement Therapy Patch
Sponsor:   Pfizer
Active, not recruiting - verified May 2015

Ponatinib - Frontline for Chronic Myeloid Leukemia (CML) in Accelerated Phase (AP)

Condition:   Leukemia
Intervention:   Drug: Ponatinib
Sponsors:   M.D. Anderson Cancer Center;   Ariad Pharmaceuticals
Active, not recruiting - verified May 2015

Perioperative Versus Postoperative Glycemia Control in Cardiac Surgery Patients

Conditions:   Perioperative and Postoperative Hyperglycemia;   Tight Glycemia Control
Intervention:   Procedure: Intensive glycemia control
Sponsor:   Charles University, Czech Republic
Completed - verified May 2015

Natural History of Carotid Atherosclerosis

Conditions:   Carotid Artery Disease;   Stroke;   Myocardial Infarction;   Angina Pectoris
Intervention:  
Sponsor:   University of Athens
Recruiting - verified May 2015

Valvuloplasty Scoring Balloon Catheter First-in-Man Study

Condition:   Aortic Valve Stenosis
Intervention:   Device: AngioScore's Valvuloplasty Scoring Balloon
Sponsor:   Spectranetics Corporation
Active, not recruiting - verified May 2015

Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Injection of Cyclosporin;   Drug: Placebo;   Procedure: Echocardiography
Sponsor:   Hospices Civils de Lyon
Active, not recruiting - verified April 2015

Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)

Condition:   Atherosclerosis
Interventions:   Drug: Canakinumab;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting - verified May 2015

International Survey of Acute Coronary Syndromes in Transitional Countries

Conditions:   Acute Coronary Syndrome;   Unstable Angina Pectoris;   Myocardial Infarction;   Coronary Disease
Intervention:  
Sponsor:   University of Bologna
Recruiting - verified May 2015

Cardiovascular Risk Factors, Lipid Metabolism and Oxidative Stress

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   University of Roma La Sapienza
Recruiting - verified May 2015

A Study of Early Robotic Ablation by Substrate Elimination of Ventricular Tachycardia

Condition:   Ventricular Tachycardia
Interventions:   Procedure: Robotic VT Ablation;   Other: Conventional Therapy
Sponsors:   Imperial College London;   Hansen Medical
Recruiting - verified September 2012

PROspective Multicenter Imaging Study for Evaluation of Chest Pain

Condition:   Chest Pain
Interventions:   Device: Coronary Angiography;   Device: Stress Echocardiogram;   Device: Nuclear Stress Test;   Device: Exercise Electrocardiogram
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified March 2015

The Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis Pilot Study (The POSEIDON-Pilot Study)

Condition:   Stem Cell Transplantation
Interventions:   Biological: Auto-hMSCs;   Biological: Allo-hMSCs
Sponsors:   University of Miami;   National Heart, Lung, and Blood Institute (NHLBI);   The EMMES Corporation
Completed - verified May 2015

CANVAS - CANagliflozin cardioVascular Assessment Study

Conditions:   Diabetes Mellitus, Type 2;   Cardiovascular Diseases;   Risk Factors
Interventions:   Drug: Canagliflozin (JNJ-28431754);   Drug: Placebo
Sponsors:   Janssen Research & Development, LLC;   The George Institute for Global Health, Australia
Active, not recruiting - verified May 2015

INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery

Condition:   Systemic Inflammatory Response Syndrome
Intervention:   Procedure: cardiac surgery with CPB use
Sponsors:   Medical University of Gdansk;   Ministry of Science and Higher Education, Poland
Completed - verified May 2015

Molecular and Morphologic Characterization of Circulating Endothelial Cells

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Scripps Translational Science Institute
Recruiting - verified May 2015

Cardiovascular Magnetic Resonance for the Occluded Infarct-Related Artery Treatment

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Myocardial Infarction;   Heart Failure
Interventions:   Drug: Beta adrenergic blockers;   Drug: Platelet inhibitors;   Drug: Statins;   Drug: ACE inhibitors and/or ARB and/or AA;   Procedure: PCI with stenting
Sponsor:   Institute of Cardiology, Warsaw, Poland
Terminated - verified May 2015

Prochymal® (Human Adult Stem Cells) Intravenous Infusion Following Acute Myocardial Infarction (AMI)

Condition:   Myocardial Infarction
Interventions:   Drug: Prochymal®;   Drug: Placebo
Sponsor:   Mesoblast International Sàrl
Active, not recruiting - verified May 2015

A Clinical Evaluation of Everolimus Eluting Coronary Stents in the Treatment of Patients With ST-segment Elevation Myocardial Infarction: EXAMINATION Study

Condition:   Myocardial Infarction
Interventions:   Drug: Everolimus Eluting Coronary Stent System;   Device: cobalt chromium balloon expandable stent ( non drug eluting stent Arm)
Sponsor:   Spanish Society of Cardiology
Completed - verified May 2015

Chronotherapy With Low-dose Aspirin for Primary Prevention

Condition:   Type 2 Diabetes
Interventions:   Drug: aspirin;   Drug: aspirin
Sponsor:   University of Vigo
Recruiting - verified May 2015

Promoting Healthy Weight With 'Stability Skills First'

Condition:   Obesity
Intervention:   Behavioral: Behavioral weight-loss/lifestyle interventions
Sponsors:   Stanford University;   National Cancer Institute (NCI)
Completed - verified May 2015

Insulin Resistance and Atherosclerosis in Women With Lupus

Conditions:   Systemic Lupus Erythematosus;   Insulin Resistance;   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed - verified May 2015

Dexamethasone to Prevent Oral Chronic Graft-versus-Host Disease

Condition:   Graft vs Host Disease
Intervention:   Drug: Topical Dexamethasone
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2015

A Study Comparing the Efficacy and Safety of Intracoronary Stenting With or Without Abciximab, an Anti-Platelet Therapy, and Conventional Coronary Angioplasty With Abciximab

Condition:   Angioplasty, Transluminal, Percutaneous Coronary
Interventions:   Other: Angioplasty;   Other: Intracoronary Stent;   Drug: Abxicimab;   Drug: Heparin;   Drug: Placebo
Sponsor:   Centocor, Inc.
Completed - verified May 2015

A Study Comparing the Efficacy and Safety of Abciximab, an Anti-Platelet Therapy, in Combination With Two Different Heparin Regimens in Patients Undergoing Percutaneous Coronary Intervention.

Condition:   Angioplasty, Transluminal, Percutaneous Coronary
Interventions:   Drug: Placebo;   Drug: Heparin;   Drug: Abciximab
Sponsor:   Centocor, Inc.
Completed - verified May 2015

Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack.

Conditions:   Ischemic Heart Failure;   Ischemic Heart Disease;   Ischemic Cardiomyopathy
Intervention:   Drug: Cellular Therapy (Cultured Autologous Skeletal Myoblast Transplantation)
Sponsor:   Genzyme, a Sanofi Company
Terminated - verified May 2015

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