Heart Attack

Clinical Trial Finder

Many patients with heart disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Home-based Cardiovascular Rehabilitation, Maintenance Phase, in Subjects With Coronary Artery Disease

Conditions:   Coronary Heart Disease;   Acute Myocardial Infarction: Rehabilitation Phase
Interventions:   Procedure: Cardiovascular rehabilitation program using Kinect of Xbox;   Procedure: Cardiovascular rehabilitation program using paper manual;   Other: Educational component
Sponsor:   Ágata Sofia da Silva Vieira
Completed - verified April 2016

Postapproval Trial On Carotid Stenting in Patients With High Risk Vs Standard Risk for Open Carotid Endarterectomy(REAL)

Condition:   Carotid Artery Diseases
Intervention:  
Sponsor:   Joaquin de Haro, M.D.
Completed - verified April 2016

Reduction to Preventive Doses of Enoxaparin After 3 to 6 Months of Treatment With Blood Thinners for Cancer-associated Blood Clots

Condition:   Deep Vein Thrombosis
Intervention:  
Sponsors:   Dr. Vicky Tagalakis;   Sanofi
Not yet recruiting - verified April 2016

Evaluation of Plasma Non-coding RNAs as Biomarkers in Coronary Heart Disease

Condition:   Coronary Disease
Intervention:   Other: No intervention
Sponsor:   Tongji Hospital
Not yet recruiting - verified April 2016

Thrombus Aspiration in Acute ST-elevation Myocardial Infarction

Condition:   Acute ST-elevation Myocardial Infarction
Intervention:  
Sponsor:   Oslo University Hospital
Recruiting - verified April 2016

Early or Delayed Revascularization for Intermediate and High-risk Non ST-elevation Acute Coronary Syndromes?

Condition:   Acute Coronary Syndrome
Intervention:   Procedure: Percutaneous coronary intervention for revascularization
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified April 2016

Safety and Feasibility of Intracoronary Hypothermia in Acute Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Other: intracoronary infusion with saline on 22 and 4°C
Sponsor:   Catharina Ziekenhuis Eindhoven
Not yet recruiting - verified April 2016

HELIox CardiOPlegia Trial During Cardiac surgERy

Condition:   C.Surgical Procedure; Cardiac
Interventions:   Other: Heliox;   Other: Standard of care
Sponsor:   David Mazer
Recruiting - verified April 2016

Gradual Reperfusion and Microvascular Integrity and Myocardial Oedema Patients Undergoing Primary PCI

Condition:   ST-elevation Acute Myocardial Infarction
Interventions:   Device: deferred coronary stenting;   Device: immediate stenting
Sponsor:   Istanbul University
Recruiting - verified April 2016

Effects of Induced Moderate HYPOthermia on Mortality in Cardiogenic Shock Patients Rescued by Veno-arterial ExtraCorporeal Membrane Oxygenation (ECMO)

Condition:   Cardiogenic Shock
Intervention:   Other: moderate hypothermia
Sponsor:   Central Hospital, Nancy, France
Not yet recruiting - verified April 2016

Sex and Gender Differences in Ischemic Heart Disease - Endocrine Vascular Disease Approach

Condition:   Myocardial Ischemia
Intervention:   Procedure: percutaneous coronary intervention
Sponsors:   University of Roma La Sapienza;   Ministry of Education, Universities and Research, Italy
Recruiting - verified April 2016

Point-of-Care Adipose-derived Cells for Hair Growth

Condition:   Androgenetic Alopecia
Interventions:   Procedure: Stromal Vascular Fraction Cells (SVF Cells) Injection;   Procedure: Liposuction;   Other: Hair Measurements
Sponsor:   University of Florida
Not yet recruiting - verified April 2016

Researching the Diagnosis and Treatment of Targeting Nano microRNA in the Patients of Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Septic Shock
Intervention:  
Sponsor:   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Active, not recruiting - verified April 2016

ShenFu Injection for Myocardial Protection in Patients With Acute ST Segment Elevation Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Drug: Shenfu Injection;   Drug: 5% Glucose Injection
Sponsors:   Beijing Anzhen Hospital;   China Resources Sanjiu Medical & Pharmaceutical Co., Ltd.
Recruiting - verified April 2016

Neurologic Injury Following Aortic Arch Replacement

Conditions:   Aortic Arch Replacement;   Hemi Arch Replacement
Interventions:   Procedure: DHCA+RCP;   Procedure: MHCA + SACP
Sponsor:   Emory University
Recruiting - verified April 2016

Basilar Artery Occlusion Chinese Endovascular Trial

Conditions:   Basilar Artery Occlusion;   Ischemic Stroke;   Cerebrovascular Disorders
Interventions:   Procedure: Mechanical embolectomy;   Drug: Medical Treatment
Sponsors:   Xuanwu Hospital, Beijing;   Zhangzhou Municipal Hospital of Fujian Province;   The First People's Hospital of Changzhou;   Xinqiao Hospital of Chongqing;   Changhai Hospital;   Baotou Central Hospital;   The 101st Hospital of Chinese People's Liberation Army;   Linyi People's Hospital;   Zhongshan People's Hospital, Guangdong, China;   PLA 264 Hospital, Taiyuan, Shanxi;   Nanjing First People's Hospital;   Tianjin TEDA Hospital;   The First Affiliated Hospital with Nanjing Medical University;   Liaocheng Third People's Hospital;   Luoyang Central Hospital Affiliated to Zhengzhou University;   Subei People's Hospital of Jiangsu Province;   PLA 148 Hospital, Zibo, Shandong;   Hebei General Hospital;   Shengli Oilfield Hospital;   The 306 Hospital of People's Liberation Army;   Shenzhen Bao'an District People's Hospital;   First Hospital of Jilin University;   Henan Provincial Hospital;   Peking University Binhai Hospital;   Beijing Tiantan Hospital;   The Military General Hospital of Beijing, PLA;   The First Affiliated Hospital of Shanxi Medical University;   The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine;   Beijing Luhe Hospital;   Nantong University;   The Affiliated Hospital Of Guizhou Medical University;   Nanning Second People's Hospital
Not yet recruiting - verified March 2016

A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Not yet recruiting - verified April 2016

Safety and Efficacy Study of a Protease Activated Receptor-4 Antagonist Being Tested to Reduce the Chances of Having Additional Strokes or "Mini Strokes"

Condition:   Thrombosis
Interventions:   Drug: BMS-986141;   Drug: Aspirin;   Other: Placebo
Sponsor:   Bristol-Myers Squibb
Not yet recruiting - verified January 2016

A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease

Condition:   Prostate Cancer
Interventions:   Drug: Degarelix;   Drug: Leuprolide
Sponsors:   Ferring Pharmaceuticals;   Memorial Sloan Kettering Cancer Center;   Duke Clinical Research Institute
Recruiting - verified April 2016

A Study of the ReCor Medical Paradise System in Clinical Hypertension

Conditions:   Hypertension;   Vascular Diseases
Interventions:   Device: The Paradise® Renal Denervation Ultrasound System;   Device: Sham Procedure
Sponsor:   ReCor Medical, Inc.
Recruiting - verified March 2016

Evaluation of the Roadsaver Stent Used in Conjunction With the Nanoparasol Embolic Protection System for Carotid Artery Stenosis

Condition:   Carotid Artery Stenosis
Interventions:   Device: Roadsaver™ Carotid Artery Stent Device;   Device: Nanoparasol® Embolic Protection System
Sponsor:   Microvention-Terumo, Inc.
Recruiting - verified April 2016

Randomized Trial of COBRA PzF Stenting to Reduce Duration of Triple Therapy

Conditions:   Angina, Stable;   Angina, Unstable;   Anticoagulants
Interventions:   Device: COBRA PzF;   Device: DES
Sponsor:   CeloNova BioSciences, Inc.
Recruiting - verified April 2016

Sleep Deficiency and Stroke Outcome

Conditions:   Sleep Apnea Syndromes;   Sleep Initiation and Maintenance Disorders;   Insomnia;   Restless Legs Syndrome;   Stroke
Intervention:  
Sponsors:   University Hospital Inselspital, Berne;   Neurocenter of Southern Switzerland;   Swiss Heart Foundation
Recruiting - verified April 2016

Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes

Condition:   Transcatheter Aortic Valve Replacement
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Acetylsalicylic acid;   Drug: Clopidogrel
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified April 2016

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified April 2016

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified April 2016

Frail Status of Elderly Patients After Repair and Anesthesia Guided by the bispectraL Index

Conditions:   Anesthesia, General;   Aged, 70 and Over
Interventions:   Other: Toolbox: Automated group;   Other: Manual group
Sponsor:   Hopital Foch
Recruiting - verified April 2016

COOL AMI EU Pilot Trial to Assess Cooling as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Device: Cooling + PCI;   Device: PCI only
Sponsor:   ZOLL Circulation, Inc., USA
Recruiting - verified April 2016

Prospective Record Of the Use of Dabigatran in Patients With Acute Stroke or TIA

Conditions:   Brain Ischemia With Non-valvular Atrial Fibrillation;   Transient Ischemic Attack With Non-valvular Atrial Fibrillation
Intervention:  
Sponsor:   University Hospital, Essen
Recruiting - verified April 2016

Early Sleeve Gastrectomy In New Onset Diabetic Obese Patients

Condition:   Type 2 Diabetes Mellitus
Interventions:   Procedure: LSG;   Drug: CMT
Sponsors:   Azienda Ospedaliera Santa Maria, Terni, Italy;   Ethicon Endo-Surgery
Recruiting - verified April 2016

Aspirin Twice a Day in Patients With Diabetes and Acute Coronary Syndrome

Conditions:   Diabetes Mellitus;   Acute Coronary Syndrome;   Coronary Artery Disease
Interventions:   Drug: Novel strategy Aspirin;   Drug: Conventional strategy Aspirin
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Bayer
Not yet recruiting - verified April 2016

The Aortic Surgery Cerebral Protection Evaluation (ACE) Randomized Trial

Condition:   Aortic Aneurysm, Thoracic
Interventions:   Procedure: Axillary artery cannulation;   Procedure: Innominate artery cannulation
Sponsors:   St. Michael's Hospital, Toronto;   London Health Sciences Centre
Recruiting - verified April 2016

A Study in Asthma Patients to Evaluate Efficacy, Safety and Tolerability of 14 Days Once Daily Inhaled Interferon Beta-1a After the Onset of Symptoms of an Upper Respiratory Tract Infection

Condition:   Asthma
Interventions:   Drug: Interferon beta-1a Nebuliser solution 48 μg/mL;   Drug: Placebo
Sponsor:   AstraZeneca
Recruiting - verified April 2016

Women's Health Initiative Strong and Healthy Study

Conditions:   Myocardial Infarction;   Stroke;   Cardiovascular Mortality;   Hip Fractures;   Falls;   Mortality;   Venous Thromboembolic Event;   Peripheral Artery Disease
Intervention:   Behavioral: Physical Activity
Sponsors:   Fred Hutchinson Cancer Research Center;   University of California, San Diego;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified April 2016

Feasibility and Effectiveness of Remote Virtual Reality-Based Cardiac Rehabilitation

Condition:   Myocardial Infarction
Intervention:   Behavioral: MedBIKE
Sponsors:   University of Alberta;   Alberta Health Services
Not yet recruiting - verified April 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified April 2016

Brilinta Taiwan Post Approval Safety Study

Condition:   Non ST-elevation Myocardial Infarction
Intervention:   Drug: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Sponsor:   AstraZeneca
Active, not recruiting - verified April 2016

The Asahi Intecc PTCA Chronic Total Occlusion Study

Conditions:   Coronary Artery Disease;   Coronary Artery Chronic Total Occlusion
Intervention:   Device: Revascularization of Coronary Artery Chronic Total Occlusion (Corsair, Gaia, Asahi Guide Wires)
Sponsors:   Asahi Intecc USA Inc;   Medpace, Inc.
Completed - verified April 2016

Early Treatment of Acute Graft Versus Host Disease With Bone Marrow-Derived Mesenchymal Stem Cells and Corticosteroids

Condition:   Graft-Versus-Host Disease
Intervention:   Biological: MSC
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified December 2015

Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults

Conditions:   HIV Infections;   Cardiovascular Diseases
Interventions:   Drug: Pitavastatin;   Drug: Placebo
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   National Heart, Lung, and Blood Institute (NHLBI);   Kowa Pharmaceuticals America, Inc.
Recruiting - verified April 2016

Curative Efficacy of Secondary Prevention for Patients With Ischemic Stroke Through Syndrome Differentiation of TCM

Condition:   Ischemic Stroke
Interventions:   Drug: Naoxintong Capsule;   Drug: Placebo
Sponsors:   Xiaofei Yu;   Shanghai Municipal Science and Technology Commission
Recruiting - verified April 2016

Effect Of Early C-PAP Treatment For Sleep Apnea On Rehabilitation Of Stroke Patients

Conditions:   Sleep Apnea;   Stroke
Interventions:   Device: Watchpat;   Device: CPAP
Sponsor:   Soroka University Medical Center
Not yet recruiting - verified April 2016

Bivalirudin Infusion for Ventricular Infarction Limitation

Condition:   Acute Myocardial Infarction
Interventions:   Procedure: primary PCI;   Drug: Bivalirudin
Sponsor:   The Medicines Company
Active, not recruiting - verified April 2016

"In Vivo" Comparison in Human Carotid Atherosclerosis: Plaque Neovascularization

Conditions:   Carotid Artery Disease;   Plaque Neovascularization
Interventions:   Other: Contrast enhanced ultrasound of the carotid plaque;   Other: Dynamic contrast-enhanced carotid plaque MRI
Sponsor:   Ospedale San Giovanni Bellinzona
Completed - verified April 2016

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified April 2016

Mechanistic Study of Bleeding Risk in Coronary Patients With Cerebrovascular Disease

Conditions:   Coronary Artery Disease;   Cerebral Stroke;   TIA (Transient Ischemic Attack)
Intervention:  
Sponsors:   University of Sao Paulo General Hospital;   Fundação de Amparo à Pesquisa do Estado de São Paulo
Completed - verified June 2014

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified April 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2016

Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial

Condition:   Coronary Disease
Interventions:   Device: computed tomography perfusion guided treatment;   Device: Fractional flow reserve guided treatment
Sponsor:   Young-Hak Kim, MD, PhD
Recruiting - verified April 2016

Telehealth Self-Management Program in Older Adults Living With Heart Failure in Health Disparity Communities

Condition:   Chronic Heart Failure
Interventions:   Device: Telehealth Self Management (TSM);   Other: Standard of Care
Sponsor:   Northwell Health
Recruiting - verified April 2016

Mineralocorticoid Receptor Antagonism Clinical Evaluation in Atherosclerosis (MIRACULOUS) Trial

Condition:   Atherosclerosis
Interventions:   Drug: Eplerenone;   Drug: Placebo
Sponsor:   University of Maryland
Recruiting - verified April 2016

Biomarkers for Post-Transplant Lymphoproliferative Disorders in Children

Conditions:   Heart Transplant;   Small Intestine Transplant;   Kidney Transplant;   Liver Transplant;   Epstein-Barr Virus-Related Post-Transplant Lymphoproliferative Disorder;   PTLDs
Interventions:   Procedure: transplant;   Drug: Immunosuppressive Drugs
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Clinical Trials in Organ Transplantation in Children
Recruiting - verified April 2016

DLBS1033 for Acute NSTEMI Without Early Coronary Revascularization

Condition:   Acute Non-ST Elevation Myocardial Infarction
Interventions:   Drug: DLBS1033;   Drug: Placebo
Sponsor:   Dexa Medica Group
Withdrawn - verified April 2016

Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

Condition:   Diabetes Type 2
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified August 2015

Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-of-Care Setting

Condition:   Congestive Heart Failure
Intervention:   Device: Samsung LABGEO IVD-A20 CHF Test
Sponsors:   Samsung Electronics;   Nexus-Dx
Terminated - verified February 2015

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   Cleveland Clinic Coordinating Center for Clinical Research (C5R);   Quintiles, Inc.
Recruiting - verified April 2016

A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients

Conditions:   Heart Failure;   Respiratory Insufficiency;   Stroke Acute;   Infectious Diseases;   Rheumatic Diseases
Interventions:   Drug: Rivaroxaban, 10 mg;   Drug: Rivaroxaban, 7.5 mg;   Drug: Placebo
Sponsor:   Janssen Research & Development, LLC
Recruiting - verified April 2016

Outcomes of Angiotensin Converting Enzyme Inhibitor Management Strategies Prior to Coronary Artery Bypass

Condition:   Coronary Artery Disease
Interventions:   Drug: ACE/ARB continuation;   Drug: ACE/ARB withdrawal
Sponsor:   University of Alberta
Recruiting - verified April 2016

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified April 2016

Individually Tailored Treatment of Type 2 Diabetes

Conditions:   Type 2 Diabetes;   Hypertension
Intervention:   Other: Individual treatment
Sponsors:   Odense University Hospital;   Region of Southern Denmark;   Hospital of South West Denmark;   General Practice Research Database
Enrolling by invitation - verified April 2016

COOL-AMI EU Case Series Clinical Study

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   ZOLL Circulation, Inc., USA
Recruiting - verified April 2016

GLORIA-AF Registry Program (Phase II/III)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified April 2016

BIOFLOW III Asia Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Diabetes Mellitus Type 1 or 2
Intervention:  
Sponsor:   BIOTRONIK Asia Pacific Pte Ltd
Active, not recruiting - verified April 2016

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified April 2016

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified April 2016

Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention

Condition:   Acute ST Segment Elevation Myocardial Infarction
Interventions:   Drug: NAC;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified April 2016

The TRUST Study - Depression Substudy

Conditions:   Subclinical Hypothyroidism;   Depression
Interventions:   Drug: Levothyroxine;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   Leiden University Medical Center;   University of Bern
Recruiting - verified April 2016

Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Interventions:   Drug: N-acetyl cysteine;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified April 2016

Comparison of the Angiographic Result of the Orsiro Hybrid Stent With Resolute Integrity Stent

Conditions:   Coronary Artery Disease;   Coronary Heart Disease;   Stable Angina;   Unstable Angina;   ST-segment Elevation Myocardial Infarction;   Non-ST-segment Elevation Myocardial Infarction
Interventions:   Device: Osiro Hybrid Drug-Eluting Stent;   Device: Resolute Integrity
Sponsors:   Seoul National University Bundang Hospital;   Jeju National University Hospital;   Chungbuk National University Hospital;   SMG-SNU Boramae Medical Center;   Korea University;   Inje University;   Kyung Hee University Hospital at Gangdong;   Inha University Hospital
Completed - verified April 2016

Myocardial Perfusion Study to Detect Coronary Microvascular Abnormality in Diabetic Patients With Nonfatal Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:  
Sponsor:   State University of New York - Upstate Medical University
Recruiting - verified April 2016

Stentys Coronary Stent System Clinical Trial in Patients With Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Device: STENTYS self-apposing stent;   Device: VISION balloon-expandable stent
Sponsor:   Stentys
Active, not recruiting - verified November 2015

Extended Venous Thromboembolism Prophylaxis Comparing Rivaroxaban to Aspirin Following Total Hip and Knee Arthroplasty

Condition:   Venous Thromboembolism
Intervention:   Drug: rivaroxaban and ASA
Sponsors:   David Anderson;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified April 2016

The Diagnosis and Treatment of Resistant Hypertension, the Prevalence and the Prognosis

Condition:   Hypertension, Resistant to Conventional Therapy
Intervention:  
Sponsors:   Chinese Academy of Medical Sciences, Fuwai Hospital;   Huazhong University of Science and Technology;   Shanghai Jiao Tong University School of Medicine
Active, not recruiting - verified April 2016

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified April 2016

Thrombus Aspiration in ThrOmbus Containing culpRiT Lesions in Non-ST-Elevation Myocardial Infarction (TATORT-NSTEMI)

Condition:   Non-ST-elevation Myocardial Infarction
Interventions:   Procedure: Thrombectomy;   Procedure: Standard percutaneous coronary intervention
Sponsor:   University of Leipzig
Active, not recruiting - verified April 2016

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

Conditions:   Obesity;   Overweight
Interventions:   Drug: NB32;   Drug: PBO;   Behavioral: Weight Management Program
Sponsor:   Orexigen Therapeutics, Inc
Terminated - verified April 2016

Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

Conditions:   Myeldysplastic Syndrome (MDS);   Chronic Myelomonocytic Leukemia;   Bone Marrow Diseases;   Neutropenia;   Acute Myeloid Leukemia (AML)
Interventions:   Drug: Clofarabine;   Drug: Lenalidomide
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   Celgene Corporation
Completed - verified February 2016

Valvuloplasty Scoring Balloon Catheter First-in-Man Study

Condition:   Aortic Valve Stenosis
Intervention:   Device: AngioScore's Valvuloplasty Scoring Balloon
Sponsor:   Spectranetics Corporation
Completed - verified April 2016

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

Condition:   Severe Aortic Stenosis
Intervention:   Device: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI)
Sponsor:   Medtronic Cardiovascular
Active, not recruiting - verified April 2016

NBS10 (Also Known as AMR-001) Versus Placebo Post ST Segment Elevation Myocardial Infarction

Condition:   ST Segment Elevation Myocardial Infarction
Interventions:   Biological: NBS10;   Other: placebo
Sponsor:   Caladrius Biosciences, Inc.
Completed - verified April 2016

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2016

Clearance Of Mucus In Stents

Conditions:   Lung Neoplasms;   Respiratory Failure;   Pneumonia;   Acute Coronary Syndromes;   Unstable Angina;   Myocardial Infarction;   Cardiac Arrhythmia;   Thromboembolic Disease
Interventions:   Other: Normal Saline;   Other: Sodium Bicarbonate
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified April 2016

Evaluation of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: follow-up coronary angiography;   Procedure: Clinical follow-up
Sponsor:   Takeshi Morimoto
Active, not recruiting - verified April 2016

The Nordic Aortic Valve Intervention Trial

Condition:   Critical Aortic Stenosis
Interventions:   Procedure: Transcatheter Aortic Valve Implantation;   Procedure: Surgical Aortic Valve Replacement
Sponsors:   Rigshospitalet, Denmark;   Odense University Hospital;   Sahlgrenska University Hospital, Sweden;   Danish Heart Foundation;   Copenhagen Trial Unit, Center for Clinical Intervention Research
Active, not recruiting - verified April 2016

GORE® HELEX® Septal Occluder / GORE® Septal Occluder for Patent Foramen Ovale (PFO) Closure in Stroke Patients - The Gore REDUCE Clinical Study

Conditions:   Stroke;   Transient Ischemic Attack
Interventions:   Device: GORE® HELEX® Septal Occluder / GORE® Septal Occluder;   Other: Antiplatelet Medical Therapy
Sponsor:   W.L.Gore & Associates
Active, not recruiting - verified April 2016

The Melatonin Adjunct in the Acute myocaRdial Infarction Treated With Angioplasty

Condition:   Acute Myocardial Infarction
Intervention:   Drug: melatonin
Sponsor:   Alberto Dominguez-Rodriguez, MD, PhD, FESC
Active, not recruiting - verified April 2016

Intraaortic Balloon Pump in Cardiogenic Shock II

Conditions:   Myocardial Infarction;   Shock, Cardiogenic
Intervention:   Device: Intraaortic balloon pump
Sponsor:   University of Leipzig
Active, not recruiting - verified April 2016

Dexamethasone to Prevent Oral Chronic Graft-versus-Host Disease

Condition:   Graft vs Host Disease
Interventions:   Drug: Topical Dexamethasone;   Drug: Placebo
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2016

Japan Statin Treatment Against Recurrent Stroke (J-STARS)

Condition:   Ischemic Stroke
Intervention:   Drug: Pravastatin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University
Completed - verified March 2015

Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome

Conditions:   Mycosis Fungoides;   Sezary Syndrome
Intervention:   Drug: Campath-1H
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2016