Diabetes and Heart Disease

Clinical Trial Finder

Many patients with type 2 diabetes are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

"The Role of the Liver for Interorgan Metabolic Crosstalk in Type 2 Diabetes"

Condition:   Type2 Diabetes
Intervention:   Drug: Metformin
Sponsors:   German Diabetes Center;   Prof. Dr. Gerald Shulman, Yale University, New Haven, Conneticut, USA
Recruiting

Comprehensive Care Protocol in New Diagnosis of Type 2 Diabetes Mellitus and Associated Comorbidities in Primary Care

Condition:   Type 2 Diabetes
Intervention:   Other: Comprehensive care protocol in new diagnosis of Type 2 Diabetes Mellitus and associated comorbidities in Primary Care
Sponsor:   Jordi Gol i Gurina Foundation
Active, not recruiting

Diet and Medical Therapy Versus Bariatric Surgery in Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Procedure: Bariatric surgery: Gastric bypass;   Procedure: Bariatric surgery: Bilio-pancreatic diversion;   Behavioral: anti-diabetic drugs and behavioral suggestions
Sponsor:   Catholic University of the Sacred Heart
Completed

Effectiveness of Pre-medical Consultation Diabetes Self-care Education Programme on Glycemic Control in Type 2 Diabetes

Condition:   Type 2 Diabetes
Intervention:   Behavioral: Pre-medical consultation structured diabetes self-care education programme
Sponsor:   Chinese University of Hong Kong
Recruiting

Genetics of Type 2 Diabetes Among Han Chinese

Conditions:   Diabetes;   Hypertension
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Completed

The Progress of Diabetes Mellitus After HMS5552 Treatment in Type 2 Diabetes Mellitus

Condition:   Type2 Diabetes Mellitus
Intervention:   Drug: HMS5552
Sponsor:   Majianhua
Not yet recruiting

Type 2 Diabetes and the Brain in Adolescents

Conditions:   Type 2 Diabetes Mellitus;   Obesity;   Pediatric Obesity;   Insulin Resistance;   Dysglycemia;   Hyperglycemia
Interventions:   Procedure: Hyperglycemic clamp;   Procedure: Hyperinsulinemic Euglycemic clamp
Sponsor:   Nemours Children's Clinic
Completed

A Study of LY2189102 in Patients With Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Drug: LY2189102;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Completed

Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in the Treatment of Type 2 Diabetes Mellitus.

Conditions:   Obesity;   Type 2 Diabetes;   Bariatric Surgery
Interventions:   Procedure: Roux-en-Y gastric bypass;   Procedure: sleeve gastrectomy
Sponsor:   Göteborg University
Recruiting

A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Dulaglutide;   Drug: Placebo;   Drug: SGLT2 inhibitor;   Drug: Metformin
Sponsor:   Eli Lilly and Company
Completed

Network-based Approach in Type 2 Diabetes and Its Cardiovascular Risk

Conditions:   Type 2 Diabetes Mellitus;   Cardiovascular Diseases
Intervention:  
Sponsor:   Giuditta Benincasa
Recruiting

Episodic to Real-Time Care in Diabetes Self-Management

Condition:   Diabetes Mellitus, Type II
Intervention:   Behavioral: Type 2 Diabetes Self-Management
Sponsor:   Duke University
Enrolling by invitation

A Study of the Glucodynamic Effects of Dulaglutide (LY2189265) in Japanese Participants With Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Drug: Dulaglutide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Completed

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)

Condition:   Type 2 Diabetes
Interventions:   Drug: Tirzepatide;   Drug: Insulin Glargine
Sponsor:   Eli Lilly and Company
Not yet recruiting

A Study of LY3209590 in Participants With Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: LY3209590;   Drug: Insulin Degludec
Sponsor:   Eli Lilly and Company
Active, not recruiting

A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Drug: Tirzepatide;   Drug: Semaglutide
Sponsor:   Eli Lilly and Company
Recruiting

A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Drug: Dulaglutide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Completed

A Study of LY900014 Compared to Insulin Lispro (Humalog) in Adults With Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: LY900014;   Drug: Insulin Lispro;   Drug: Insulin Glargine;   Drug: Insulin Degludec
Sponsor:   Eli Lilly and Company
Recruiting

Effects and Safety of OPK-88003 Dose Escalation in Type 2 Diabetes Subjects

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: OPK-88003;   Drug: Placebo
Sponsors:   OPKO Ireland Global Holdings Ltd.;   OPKO Health, Inc.
Completed

A Study of LY2963016 Compared to Lantus® in Adult Chinese Participants With Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes
Interventions:   Drug: LY2963016;   Drug: Lantus®
Sponsor:   Eli Lilly and Company
Recruiting

A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin

Condition:   Type 2 Diabetes
Interventions:   Drug: Tirzepatide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting

A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Tirzepatide;   Drug: Insulin Degludec
Sponsor:   Eli Lilly and Company
Recruiting

The Set-Point Study for Type 2 Diabetes: Evaluating the Use of an Insulin Only Bionic Pancreas System in Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Device: Bionic Pancreas;   Other: Usual Care
Sponsor:   Massachusetts General Hospital
Completed

A Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Drug: Dulaglutide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Tirzepatide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting

Impact on Glycemic Variability After Treatment With Dapagliflozin on Type 2 Diabetes Patients

Condition:   Type 2 Diabetes
Intervention:   Diagnostic Test: Continuous glucose monitoring
Sponsors:   Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran;   AztraZeneca
Recruiting

A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Tirzepatide;   Drug: Insulin Glargine
Sponsor:   Eli Lilly and Company
Recruiting

A Study on Comparison of Glargine Plus Glulisine With Premixed Insulin in Type 2 Diabetes Patients

Condition:   Type2 Diabetes
Interventions:   Drug: Glargine + Glulisine;   Drug: Premixed analogue insulin (70/30)
Sponsor:   India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals
Completed

Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy Study

Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Abnormal Glucose Metabolism;   Type 2 Diabetes
Intervention:   Behavioral: Assignment of a Lay Patient Partner
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

A Study Comparing the Effects and Safety of Dulaglutide With Glimepiride in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Dulaglutide;   Drug: Glimepiride;   Drug: Placebo as Capsules;   Drug: Placebo as SC Injection
Sponsor:   Eli Lilly and Company
Completed

A Study Comparing the Effects and Safety of Dulaglutide With Insulin Glargine in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Dulaglutide;   Drug: Insulin glargine;   Drug: Metformin;   Drug: Sulfonylureas
Sponsor:   Eli Lilly and Company
Completed

A Study to Compare the Effect of a Double Dose of Two Long-acting Insulin Therapies in Participants With Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Insulin Peglispro;   Drug: Insulin Glargine
Sponsor:   Eli Lilly and Company
Completed

The Imaging Genetic Study of Type 2 Diabetes and Depression

Condition:   T2DM
Intervention:   Device: Magnetic resonance
Sponsor:   Kunming Medical University
Recruiting

Metabolic Causes of Thrombosis in Type 2 Diabetes - Question 4

Condition:   Type 2 Diabetes
Intervention:   Other: Hyperinsulinemic Hypoglycemic Clamp
Sponsors:   University of Maryland, Baltimore;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Study to Evaluate Safety and Efficacy of Dapagliflozin and Saxagliptin in Patients With Type 2 Diabetes Mellitus Aged 10 to Below 18 Years Old

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Dapagliflozin;   Drug: Saxagliptin;   Drug: Placebo
Sponsor:   AstraZeneca
Recruiting

Pharmacist-Led Study in Controlling Hypoglycemia in Older Adults With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus Type 2 With Hypoglycemia
Intervention:   Behavioral: SUGAR Handshake
Sponsor:   University of Lincoln
Not yet recruiting

A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)

Conditions:   Type 2 Diabetes;   Chronic Kidney Disease
Interventions:   Drug: Dulaglutide;   Drug: Insulin glargine;   Drug: Insulin lispro
Sponsor:   Eli Lilly and Company
Completed

An International Survey of the Occurrence of Cardiovascular Disease Among Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Other: No treatment given
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

Mechanistic Evaluation of Glucose-lowering Strategies in Patients With Heart Failure

Conditions:   Type 2 Diabetes Mellitus;   Heart Failure
Interventions:   Drug: Saxagliptin;   Drug: Sitagliptin;   Drug: Placebo to match saxagliptin;   Drug: Placebo to match sitagliptin
Sponsor:   AstraZeneca
Completed

Effect of Liraglutide on the Metabolic Profile in Patients With Type 2 Diabetes and Cardiovascular Disease

Conditions:   Type 2 Diabetes;   Cardiovascular Diseases
Interventions:   Drug: Liraglutide Pen Injector [Victoza];   Drug: Placebo
Sponsors:   RWTH Aachen University;   Novo Nordisk A/S
Not yet recruiting

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Active, not recruiting

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin 5 mg;   Drug: Ertugliflozin 15 mg;   Drug: Placebo;   Biological: Insulin;   Drug: Metformin
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Not yet recruiting

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: Finerenone (BAY94-8862);   Drug: Placebo
Sponsor:   Bayer
Active, not recruiting

Evaluate the Efficacy and Safety of Insulin in Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Human Insulin Inhalation Powder;   Drug: Insulin Glargine
Sponsors:   Eli Lilly and Company;   Alkermes, Inc.
Completed

Metabolic Causes of Thrombosis in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes
Interventions:   Procedure: euinsulinemic euglycemic glucose clamp;   Procedure: euinsulinemic hyperglycemic glucose clamp;   Procedure: Hyperinsulinemic euglycemic glucose clamp;   Procedure: Hyperinsulinemic hyperglycemic glucose clamp
Sponsors:   University of Maryland, Baltimore;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Omarigliptin Add-on to Insulin in Japanese Participants With Type 2 Diabetes Mellitus (T2DM, MK-3102-039)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Omarigliptin;   Drug: Placebo;   Biological: Insulin
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Weight Loss-Independent Metabolic Effects of Roux-En-Y Gastric Bypass in Diabetes

Conditions:   Obesity;   Type 2 Diabetes
Interventions:   Procedure: Roux-en-Y gastric bypass surgery;   Behavioral: Low-calorie diet;   Procedure: SG
Sponsors:   Washington University School of Medicine;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Active, not recruiting

QR-Bromocriptine as an Adjunct to Insulin and Metformin in the Treatment of Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: QR-bromocriptine
Sponsor:   University of Texas Southwestern Medical Center
Completed

The Study Will Evaluate Average 24-hr Sodium Excretion During Dapagliflozin Treatment in Patients With Type 2 Diabetes Mellitus With Preserved or Impaired Renal Function or Non-diabetics With Impaired Renal Function.

Conditions:   Diabetes Mellitus, Type 2;   Kidney Function Tests
Intervention:   Drug: Dapagliflozin
Sponsor:   AstraZeneca
Recruiting

Acute Mycoprotein Effect on Glycaemic Control in South Asians

Condition:   Type 2 Diabetes Mellitus
Intervention:   Other: Test food containing different types of dietary protein
Sponsor:   Imperial College London
Recruiting

Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes Mellitus

Conditions:   Obesity;   Overweight;   Diabetes Mellitus, Type 2
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Effect of Liraglutide on Diastolic Dysfunction on Cardiac MRI in Type 2 Diabetes Patients

Conditions:   Diabetes Mellitus Type 2;   Diastolic Dysfunction;   Cardiac MRI;   Myocardial Perfusion
Interventions:   Drug: Liraglutide;   Drug: Placebo
Sponsors:   Rigshospitalet, Denmark;   Slagelse Hospital;   Novo Nordisk A/S
Active, not recruiting

Probiotics in Metformin Intolerant Patients With Type 2 Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Metformin Adverse Reaction
Interventions:   Dietary Supplement: Sanprobi Barrier-multispecies probiotic;   Other: Placebo Comparator
Sponsors:   Medical University of Silesia;   Sanprobi Sp. z o.o., Sp. k., Szczecin, Poland
Recruiting

Study of Gelesis100 on Body Weight in Overweight and Obese Subjects With and Without Type 2 Diabetes

Conditions:   Overweight;   Obesity
Interventions:   Device: Gelesis100;   Device: placebo
Sponsor:   Gelesis, Inc.
Completed

Microcirculation and Bone Metabolism in Patients With Type 2 Diabetes Mellitus and Charcot Foot - A Pilot Study

Conditions:   Diabetic Angiopathies;   Bone Diseases, Metabolic
Intervention:   Other: Baseline comparison of microcirculation and bone metabolism
Sponsors:   Tameside General Hospital;   Manchester Metropolitan University
Completed

The MILESTONE Study

Condition:   Type 2 Diabetes Mellitus
Intervention:   Device: Endovascular Denervation
Sponsor:   Zhongda Hospital
Recruiting

Effect of Whole Fruit on Glycemic Control in Adults With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Behavioral: High-Fruit Diet
Sponsor:   University of Alabama at Birmingham
Recruiting

TELE-DD Project: a Joint Prospective Cohort Study and Nurse-led Randomised Controlled Trial on Treatment Adherence in Patients With Type 2 Diabetes and Clinical Depression

Conditions:   Diabetes Mellitus, Type 2;   Depression
Intervention:   Behavioral: Telephone Intervention Group
Sponsors:   Instituto de Investigación Sanitaria Aragón;   Universidad de Zaragoza
Active, not recruiting

A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Placebo (semaglutide)
Sponsor:   Novo Nordisk A/S
Recruiting

CSII Pilot in Adolescents With Type 2 Diabetes

Condition:   Diabetes
Intervention:   Other: MMT 723
Sponsor:   NYU Langone Health
Terminated

A Study of LY3305677 in Participants With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: LY3305677;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Not yet recruiting

A Research Study, Looking at How Tresiba® Works in People With Type 2 Diabetes in Local Clinical Practice in Saudi Arabia

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Insulin degludec
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

A Study to Evaluate the Effect of MEDI0382 on Energy Balance in Overweight and Obese Subjects With Type 2 Diabetes Mellitus

Conditions:   Diabetes Mellitus, Type II;   Obesity
Interventions:   Drug: MEDI0382;   Drug: Placebo
Sponsor:   MedImmune LLC
Active, not recruiting

Long Term Daily Use of JARDIANCE® Tablets in Japanese Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Jardiance
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Active, not recruiting

Mechanisms of Ramipril Reduction in the Onset of Type 2 Diabetes

Condition:   Metabolic Syndrome
Interventions:   Drug: Ramipril;   Drug: HCTZ-hydrochlorothiazide;   Drug: Ramipril+HCTZ
Sponsors:   University of Maryland, Baltimore;   King Pharmaceuticals is now a wholly owned subsidiary of Pfizer
Terminated

A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Placebo
Sponsor:   Novo Nordisk A/S
Recruiting

CMR in Type 2 Diabetes Mellitus Patients

Conditions:   Diabetes Mellitus, Type 2;   Heart Disease
Interventions:   Other: Cardiac Magnetic Resonance Imaging (CMR);   Other: Echocardiography;   Other: Bood samples
Sponsor:   Slagelse Hospital
Completed

A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus

Conditions:   Diabetes Mellitus, Type 2;   Hypoglycemia
Interventions:   Drug: Tirzepatide;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Not yet recruiting

Phase 2 Study of TMX-049 in Subjects With Type 2 Diabetes and Albuminuria

Condition:   Diabetic Kidney Disease
Interventions:   Drug: TMX-049;   Drug: Placebo
Sponsor:   Teijin America, Inc.
Completed

Long-term Daily Use of Trazenta® Tablets in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: OAD;   Drug: Trazenta
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Completed

A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: PF-06882961
Sponsor:   Pfizer
Not yet recruiting

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Placebo (semaglutide)
Sponsor:   Novo Nordisk A/S
Recruiting

Continuation of Metformin to Improve And Keep Peri-operative Glycemic Control

Condition:   Diabetes Mellitus Type 2
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsor:   McMaster University
Not yet recruiting

A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Oral semaglutide;   Drug: Sitagliptin;   Drug: Placebo (oral semaglutide);   Drug: Placebo (sitagliptin)
Sponsor:   Novo Nordisk A/S
Recruiting

Efficacy and Safety Study of Pitavastatin Compared to atoRvastatin in Type 2 dIabeTes Mellitus With Hypercholesterolemia

Condition:   Hypercholesterolemia With Type2DM
Interventions:   Drug: Pitavastatin;   Drug: Atorvastatin
Sponsor:   JW Pharmaceutical
Completed

Influence of Nitrates on Bone Remodeling and Endothelial Function in Patients With Type 2 Diabetes Mellitus

Conditions:   Endothelial Dysfunction;   Bone Disease
Intervention:   Other: Isosorbide-5-mononitrate
Sponsor:   Tameside Hospital NHS Foundation Trust
Withdrawn

A Research Study to Compare Semaglutide to Insulin Aspart, When Taken Together With Metformin and Insulin Glargine, in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Insulin aspart;   Drug: Insulin glargine U100
Sponsor:   Novo Nordisk A/S
Recruiting

A Multiple Ascending Dose Study to Evaluate Safety and Tolerability of BFKB8488A in Participants With Type 2 Diabetes Mellitus and Participants With Non-Alcoholic Fatty Liver Disease

Conditions:   Diabetes Mellitus, Type 2;   Non-Alcoholic Fatty Liver Disease
Interventions:   Drug: BFKB8488A;   Other: Placebo
Sponsor:   Genentech, Inc.
Recruiting

A Concordance Study Comparing Insulin Treatments in Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Human Insulin Inhalation Powder;   Drug: Insulin
Sponsor:   Eli Lilly and Company
Completed

DIA_CENTRAL:T2D Treatment Pattern in Central Europe

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Empagliflozin;   Drug: Sodium Glucose Transporter 2 inhibitor;   Drug: Dipeptidyl-peptidase 4 inhibitor;   Drug: Glucagon-like peptide 1 agonist
Sponsor:   Boehringer Ingelheim
Active, not recruiting

Study of Human Insulin Inhalation Powder in Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Human Insulin Inhalation Powder;   Drug: Injectable insulin
Sponsors:   Eli Lilly and Company;   Alkermes, Inc.
Completed

A Research Study to Compare Two Doses of Semaglutide Taken Once Weekly in People With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Placebo (semaglutide)
Sponsor:   Novo Nordisk A/S
Recruiting

Using Nanotechnology Structured Water to Control Blood Glucose in Type 2 Diabetic Patients.

Condition:   Type2 Diabetes
Interventions:   Dietary Supplement: Nanotechnology structured water ( Magnalife);   Dietary Supplement: ordinary water
Sponsor:   ALI KAMAL M. SAMI
Completed

´Sit Less, Move More` at Work: mHealth Intervention on Office Employees With Diabetes Type 2.

Condition:   Diabetes Mellitus, Type II
Intervention:   Behavioral: Walk@WorkApp-Diab
Sponsors:   Jordi Gol i Gurina Foundation;   Instituto de Salud Carlos III;   Consorci Hospitalari de Vic;   Institut Català de la Salut;   University of Vic - Central University of Catalonia;   Puerta de Hierro University Hospital
Recruiting

Regulation of Endogenous Glucose Production by Central KATP Channels

Conditions:   Type 2 Diabetes Mellitus;   Glucose Metabolism Disorders;   Glucose, High Blood
Interventions:   Drug: Diazoxide;   Drug: Nicotinic acid;   Drug: Placebo
Sponsors:   Albert Einstein College of Medicine;   National Institutes of Health (NIH);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Contrast Nephropathy in Type 2 Diabetes

Conditions:   Kidney Function Affection Upon Exposure to Radiocontrast;   Diabetes;   Microalbuminuria
Intervention:   Drug: Linagliptin Oral Tablet
Sponsor:   Ahmed Abdelkawi Hammad
Completed

A Phase IV Study in Drug-Naive Patients With T2DM in China

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Dapagliflozin;   Drug: Acarbose
Sponsor:   AstraZeneca
Recruiting

Effectiveness of Foot Exercise People With Type 2 Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Peripheral Neuropathy
Interventions:   Other: Routine rehabilitation program patient education;   Other: Routine rehabilitation program + foot exercise training
Sponsor:   Istanbul University
Active, not recruiting

Effect of a Dietary Intervention on Intracellular Lipid, Insulin Sensitivity, and Glycemic Control in Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Behavioral: Dietary intervention
Sponsors:   Physicians Committee for Responsible Medicine;   Yale University
Not yet recruiting

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in France, as Part of Local Clinical Practice (SURE FRANCE)

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: semaglutide
Sponsor:   Novo Nordisk A/S
Not yet recruiting

A Research Study, Looking at How Ryzodeg® (Insulin Degludec/Insulin Aspart) Works in People With Type 2 Diabetes in Local Clinical Practice

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Insulin Degludec/Insulin Aspart
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

Network Medicine, Epigenetics and Obesity

Conditions:   Obesity;   Type2 Diabetes
Intervention:   Other: DNA methylome and total RNA sequencing
Sponsor:   University of Campania "Luigi Vanvitelli"
Not yet recruiting

A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 to <18 Years) With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Canagliflozin 100 mg;   Drug: Canagliflozin 300 mg;   Drug: Placebo
Sponsor:   Janssen Research & Development, LLC
Recruiting

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Italy, as Part of Local Clinical Practice

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Semaglutide
Sponsor:   Novo Nordisk A/S
Not yet recruiting

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Canada, as Part of Local Clinical Practice

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Semaglutide
Sponsor:   Novo Nordisk A/S
Active, not recruiting

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Switzerland, as Part of Local Clinical Practice (SURE SWITZERLAND)

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Semaglutide
Sponsor:   Novo Nordisk A/S
Active, not recruiting

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Denmark and Sweden, as Part of Local Clinical Practice (SURE DENMARK/SWEDEN)

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Semaglutide
Sponsor:   Novo Nordisk A/S
Active, not recruiting

Self-care Management Programme for Type 2 Adult DM Patients With Poor Glycemic Control

Condition:   Type 2 Diabetes
Intervention:   Other: nursing education
Sponsor:   Chinese University of Hong Kong
Completed

Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide

Conditions:   Diabetes Mellitus, Type 2;   Glucose, High Blood;   Glucose Metabolism Disorders (Including Diabetes Mellitus)
Interventions:   Drug: Diazoxide;   Drug: Placebo
Sponsors:   Albert Einstein College of Medicine;   National Institutes of Health (NIH);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Empa PASS on Urinary Tract Malignancies

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: empagliflozin;   Drug: DPP-4 inhibitors;   Drug: SGLT-2 inhibitors
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Active, not recruiting

The Effect of Different Training Programs on Patients With Chronic Diseases

Conditions:   Hypertension;   Hypertension Complicated With Type 2 Diabetes;   Walking;   Chinese Square Dancing
Interventions:   Behavioral: Walking;   Behavioral: Chinese square dancing group;   Behavioral: Control group
Sponsors:   Beijing Sport Uninversity;   Peking University
Recruiting

Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 Diabetes

Conditions:   Obesity;   Diabetes
Interventions:   Other: Quercetin;   Other: Placebo
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Improving Medication Adherence in Older African Americans With Diabetes

Conditions:   Type 2 Diabetes;   Mild Cognitive Impairment
Interventions:   Behavioral: Primary Care-Occupational Therapy;   Behavioral: Enhanced Usual Care
Sponsors:   Thomas Jefferson University;   Johns Hopkins University
Active, not recruiting

Forxiga Tablets Specific Clinical Experience Investigation for Long-term Use

Condition:   Type 2 Diabetes Mellitus
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting

GLP-1 and Hypoglycemia

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Glucagon-Like Peptide- 1 (GLP-1) infusion;   Other: Placebo Comparator: Saline Infusion
Sponsor:   University of Maryland, Baltimore
Active, not recruiting

ENhancing Outcomes Through Goal Assessment and Generating Engagement in Diabetes Mellitus

Condition:   Diabetes Mellitus Type 2
Intervention:   Behavioral: Shared Decision Making
Sponsors:   AstraZeneca;   Brigham Women's Health
Completed

Acute Kidney Injury in Patients on Dapagliflozin and Other Antidiabetic Medications

Condition:   Acute Kidney Injury
Intervention:  
Sponsor:   AstraZeneca
Recruiting

Acute Liver Injury in Patients on Dapagliflozin

Condition:   Acute Liver Injury
Intervention:  
Sponsor:   AstraZeneca
Recruiting

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Linagliptin;   Drug: Empagliflozin;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Recruiting

Complications of UTI in Patients on Dapagliflozin

Condition:   Severe Complications of Urinary Tract Infections
Intervention:  
Sponsor:   AstraZeneca
Recruiting

Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM

Conditions:   NASH - Nonalcoholic Steatohepatitis;   NAFLD;   T2DM (Type 2 Diabetes Mellitus)
Interventions:   Drug: Foralumab;   Other: placebo;   Drug: Omeprazole 20mg
Sponsor:   Tiziana Life Sciences, PLC
Withdrawn

Impact of App Based Diabetes Training Program in Conjunction With the BD Nano Pen Needle in People With T2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Device: BD Diabetes Care Application (for mobile devices) PLUS use of BD Nano Pen Needle
Sponsor:   Becton, Dickinson and Company
Recruiting

Cancer in Patients on Dapagliflozin and Other Antidiabetic Treatment

Conditions:   Breast Cancer;   Bladder Cancer
Intervention:  
Sponsor:   AstraZeneca
Recruiting

Building Self-regulation Capacity in AA T2DM Women: Feasibility of EMI

Conditions:   Type 2 Diabetes;   Self-regulation
Intervention:   Behavioral: Feasibility group
Sponsors:   University of Illinois at Chicago;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of Chicago
Not yet recruiting

A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo (ACHIEVE CONTROL REAL LIFE STUDY PROGRAM)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Insulin glargine, 300 U/ml;   Drug: Insulin glargine, 100 U/ml;   Drug: Insulin detemir;   Drug: Background Therapy
Sponsor:   Sanofi
Completed

Criticality Analysis of Diabetic Gait Within a Primary Care Pediatric Clinic for Obese Children (PAIDOS)

Condition:   Childhood Obesity
Intervention:   Diagnostic Test: Gait analysis
Sponsors:   Dr Salvador Villalpando-Carrion;   Oxford Brookes University
Active, not recruiting

The Men Are Now United Program

Condition:   Type2 Diabetes
Intervention:   Behavioral: Intervention Group
Sponsors:   Michigan State University;   University of Michigan;   Claremont Graduate University
Active, not recruiting

Group Versus Traditional Prenatal Care for Diabetes

Conditions:   Pregnancy;   Gestational Diabetes;   Type 2 Diabetes
Intervention:   Behavioral: Group prenatal care
Sponsor:   Washington University School of Medicine
Recruiting

Empaglifozin in Early Diabetic Kidney Disease

Conditions:   Diabetic Kidney Disease;   Diabetes Mellitus Type 2
Interventions:   Drug: Empagliflozin;   Other: Placebo
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting

A Study Investigating the Pharmacokinetics of a Single Dose Administration of Cotadutide

Condition:   Type 2 Diabetes Mellitus
Intervention:   Combination Product: cotadutide multidose pen injection
Sponsor:   MedImmune LLC
Not yet recruiting

Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome

Conditions:   Type 2 Diabetes Mellitus;   Chronic Kidney Disease;   Left Ventricular Diastolic Dysfunction
Interventions:   Drug: BYDUREON;   Drug: Placebo
Sponsor:   Baylor Research Institute
Recruiting

Safety and Efficacy of Dapagliflozin in Asian T2DM Subjects With Inadequate Glycemic Control on Metformin/Saxagliptin

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Dapagliflozin 10 mg;   Drug: Dapagliflozin 5 mg;   Drug: Dapagliflozin 10 mg placebo to match;   Drug: Dapagliflozin 5 mg placebo to match;   Drug: Saxagliptin 5 mg;   Drug: Metformin
Sponsor:   AstraZeneca
Recruiting

Using Peer Mentors to Support PACT Team Efforts to Improve Diabetes Control

Condition:   Type 2 Diabetes Mellitus
Intervention:   Behavioral: Peer Mentoring
Sponsor:   VA Office of Research and Development
Completed

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

Conditions:   Diabetes;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Enrolling by invitation

A Study in Participants With Diabetic Kidney Disease

Conditions:   Diabetic Kidney Disease;   Diabetic Nephropathy;   Diabetic Glomerulosclerosis
Interventions:   Drug: LY2382770;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Terminated

A Study Comparing the Injection Site Pain Experience After the Injection of 2 Different Solutions of Semaglutide With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and Obesity

Conditions:   Healthy Volunteers Diabetes Mellitus, Type 2;   Healthy Volunteers Overweight;   Healthy Volunteers Obesity
Interventions:   Drug: Semaglutide (administered by DV3396 pen);   Drug: Semaglutide (administered by PDS290 pen)
Sponsor:   Novo Nordisk A/S
Completed

Toe-brachial Index and Coronary Calcification in Type 1 and 2 Diabetes

Condition:   Coronary Artery Calcification
Intervention:   Other: Data collection
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting

Prospective Metabolic Surgery in T2DM Chinese Subjects

Conditions:   Diabetes;   Obesity
Interventions:   Procedure: Roux-en-Y gastric bypass;   Procedure: Sleeve gastrectomy
Sponsor:   Ethicon Endo-Surgery
Active, not recruiting

Pistachios Blood Sugar Control, Heart and Gut Health

Conditions:   Type 2 Diabetes;   Cardiovascular Diseases
Interventions:   Drug: Pistachio;   Other: Usual care
Sponsor:   Penn State University
Recruiting

A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (D) Semaglutide Tablets

Conditions:   Healthy Volunteers;   Type 2 Diabetes
Intervention:   Drug: Oral semaglutide
Sponsor:   Novo Nordisk A/S
Not yet recruiting

Effects of the GOLO for Life System Diet With and Without GOLO Release Supplement on Glycemic Control and Insulin Resistance

Condition:   Diabetes Mellitus, Type 2
Interventions:   Dietary Supplement: RELEASE;   Dietary Supplement: Placebo
Sponsor:   Golo
Not yet recruiting

Urinary Vitamin C Loss in Diabetic Subjects

Conditions:   Diabetes Type 1;   Diabetes Type 2;   Healthy Volunteers
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Diabetes: Functional Medicine Approach vs. Usual Care

Conditions:   Diabetes;   Type 2 Diabetes;   Type 2 Diabetes Treated With Insulin
Intervention:   Dietary Supplement: Functional Medicine
Sponsor:   The Cleveland Clinic
Recruiting

Determinants of Bone and Muscle Quality and Strength in Obesity With and Without Diabetes

Conditions:   Diabetes Mellitus;   Diabetes Mellitus, Type 2;   Obesity;   Body Weight;   Bone Diseases, Metabolic;   Fractures, Bone;   Osteoporotic Fractures;   Osteoporosis;   Quality of Life;   Fall;   Musculoskeletal Diseases
Intervention:  
Sponsors:   Suzanne Morin;   CHU de Quebec-Universite Laval
Not yet recruiting

A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome

Condition:   Cushing Syndrome
Interventions:   Drug: Relacorilant;   Other: Placebo
Sponsor:   Corcept Therapeutics
Recruiting

Feasibility Study of DermGEN for Diabetic Foot Ulcer Treatment

Conditions:   Diabetes Type I;   Diabetes Type II
Intervention:   Biological: DermGEN
Sponsors:   Dr. Paul F. Gratzer;   Canadian Institutes of Health Research (CIHR);   Nova Scotia Health Authority
Completed

Acute Study of Effect of Ultrasound Vagus Nerve Stimulation on Glycemia

Condition:   Diabetes Mellitus, Type 2
Intervention:   Device: Ultrasound Vagus Nerve Stimulation (DECIMA)
Sponsors:   Aucta Technologies, Inc.;   STATKING Clinical Services
Recruiting

The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients

Conditions:   Diabetes Mellitus, Type 2;   Glucose, High Blood;   Glucose Metabolism Disorders
Interventions:   Drug: Diazoxide;   Drug: Placebo (for diazoxide);   Drug: Nicotinic acid
Sponsor:   Albert Einstein College of Medicine
Recruiting

Integrated NCD Intervention in Rural Nepal

Conditions:   Noncommunicable Diseases;   Hypertension;   Chronic Obstructive Pulmonary Disease;   Diabetes Mellitus, Type 2
Intervention:   Other: Bundled NCD WHO PEN Intervention
Sponsors:   Possible;   Nyaya Health Nepal;   Government of Nepal, Ministry of Health and Population
Not yet recruiting

Changes in Insulin Sensitivity After Weight Loss

Conditions:   Obesity;   Type 2 Diabetes Mellitus;   Insulin Resistance
Interventions:   Procedure: Gastric bypass;   Procedure: Gastric banding;   Procedure: Sleeve gastrectomy;   Behavioral: Very low calorie diet
Sponsors:   Columbia University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Insulin Start Therapy Application With Resources and Training

Condition:   Diabetes Mellitus, Type 2
Interventions:   Behavioral: I-START;   Behavioral: Standard Insulin Administration Education
Sponsor:   University of Pittsburgh
Not yet recruiting

DHS MIND Metabolomics

Condition:   Diabetes
Intervention:  
Sponsors:   Wake Forest University Health Sciences;   National Institute on Aging (NIA)
Recruiting

Injection of Subcutaneous Glucose 10% in Small Shots is Effective in the Treatment of Diabetic Neuropathic Pain

Condition:   Painful Diabetic Neuropathy
Intervention:   Drug: GLUCOSE 10%
Sponsor:   Ministry of Health and Population, Egypt
Recruiting

Effect of Chronic Incretin-based Therapy in Cystic Fibrosis

Conditions:   Cystic Fibrosis;   Pancreatic Insufficiency
Intervention:   Drug: Sitagliptin
Sponsors:   University of Pennsylvania;   Children's Hospital of Philadelphia
Active, not recruiting

Initiate and Maintain Physical Activity in Clinics: The IMPACT Diabetes Study

Condition:   Diabetes Mellitus
Intervention:   Behavioral: Structured Group Exercise
Sponsor:   Stanford University
Active, not recruiting

Diabetes Complication Control in Community Clinics (D4C) Trial

Conditions:   Diabetes;   Hypertension;   Dyslipidemia;   Cardiovascular Disease
Intervention:   Other: Protocol-based integrated care
Sponsors:   Tulane University;   Xiamen University
Active, not recruiting

A French Study to Evaluate the Usefulness of Implantable Continuous Glucose Monitoring (CGM) Sensor to Improve Glycemic Control in Participants With Diabetes Mellitus.

Condition:   Diabetes Mellitus
Interventions:   Device: Eversense XL;   Device: Usual SMBG or FGM device used by participants
Sponsors:   Hoffmann-La Roche;   Roche Diabetes Care France SAS
Recruiting

Safety and Efficacy of Inhaled Insulin in Patients With Diabetes and Asthma or COPD

Conditions:   Diabetes Mellitus;   Asthma;   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Human Insulin Inhalation Powder;   Drug: injected insulin
Sponsors:   Eli Lilly and Company;   Alkermes, Inc.
Completed

Effects of Fruit Extracts on Glycaemia: The GLU-FRU Study

Condition:   Postprandial Hyperglycemia
Intervention:   Dietary Supplement: Polyphenols
Sponsor:   King's College London
Completed

A Study of LY900020 in Healthy Chinese Participants

Condition:   Healthy
Interventions:   Drug: LY900020;   Drug: Metformin XR;   Drug: Atorvastatin;   Drug: Valsartan
Sponsor:   Eli Lilly and Company
Not yet recruiting

The Impact of Bariatric Surgery on Non-alcoholic Fatty Liver Disease

Conditions:   Obesity;   NAFLD
Intervention:   Procedure: Bariatric surgery
Sponsor:   Jagiellonian University
Completed

North China Metabolic Surgery Database

Condition:   Metabolic Surgery
Intervention:  
Sponsors:   Beijing Friendship Hospital;   Beijing Tiantan Hospital;   Beijing Shijitan Hospital;   Beijing Hospital;   Peking Union Medical College Hospital;   Shanxi Dayi Hospital;   The Second Hospital of Hebei Medical University;   Tianjin Medical University General Hospital;   Inner Mongolia People's Hospital;   Henan Provincial Hospital;   Qilu Hospital of Shandong University;   The First Hospital of Hebei Medical University;   The Second People's Hospital of Xinxiang Henan;   Tangshan Gongren Hospital;   Tianjin Nankai Hospital;   Tianjin First Central Hospital
Enrolling by invitation

Beijing Friendship Hospital Metabolic Surgery Database

Condition:   Metabolic Surgery
Intervention:  
Sponsor:   Beijing Friendship Hospital
Recruiting

Metabolic Effects of the SGLT-2 Inhibitor Empagliflozin in Patients With Diabetic Nephropathy (MEDiaN)

Condition:   Diabetic Nephropathies
Intervention:   Drug: Empagliflozin 10 MG
Sponsors:   Singapore General Hospital;   Duke-NUS Graduate Medical School
Recruiting

Mycoprotein Consumption and Glucose Absorption

Condition:   Healthy
Intervention:   Dietary Supplement: Mycoprotein Ingestion
Sponsors:   University of Exeter;   Quorn Foods
Recruiting

Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD).

Conditions:   Diabetes;   Diabetes Mellitus, Type 1;   Diabetes Mellitus, Type 2
Intervention:   Device: Continuous Glucose Monitor
Sponsors:   University of Virginia;   DexCom, Inc.
Not yet recruiting

CTSI Pilot: Improving Adherence to Diabetic Diet

Conditions:   Diabetes Mellitus, Type 2;   Diet, Healthy;   Pre-diabetes
Interventions:   Behavioral: Online - use of online grocery shopping platform;   Behavioral: Default - use of online grocery shopping platform with default shopping carts
Sponsor:   State University of New York at Buffalo
Recruiting

Study of Time-restricted Eating on Weight Loss.

Conditions:   Obesity;   Insulin Resistance
Interventions:   Behavioral: Time-restricted Eating plan;   Behavioral: Consistent Meal timing plan
Sponsors:   University of California, San Francisco;   University of Wisconsin, Madison
Active, not recruiting

Effect of Dietary Protein and Energy Restriction in the Improvement of Insulin Resistance in Subjects With Obesity

Conditions:   Obesity;   Insulin Resistance
Interventions:   Dietary Supplement: Normoprotein diet with animal protein;   Dietary Supplement: Normoprotein diet with vegetable protein;   Dietary Supplement: High-protein diet with animal protein;   Dietary Supplement: High-protein diet with vegetable protein
Sponsor:   Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Recruiting

Liraglutide in Adolescents With Type 1 Diabetes

Condition:   Type 1 Diabetes
Intervention:   Drug: Liraglutide
Sponsor:   University at Buffalo
Recruiting

A Research Study of How a New Medicine NNC0148-0287 C (Insulin 287) Works in the Body of People With Kidney Problems

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Insulin 287
Sponsor:   Novo Nordisk A/S
Completed

A Smartphone Application to Support Physical Activity in HIV Infected People

Conditions:   Physical Activity;   HIV Infections
Intervention:   Behavioral: Physical Activity
Sponsors:   Scientific Institute San Raffaele;   University of Milan;   Catholic University of the Sacred Heart;   IRCCS Lazzaro Spallanzani;   University of Roma La Sapienza
Completed

Effects of Fenofibrate Therapy in Diabetic Nephropathy

Conditions:   Diabetes Mellitus;   Diabetic Nephropathies
Intervention:   Drug: Fenofibrate
Sponsors:   Singapore General Hospital;   National Medical Research Council (NMRC), Singapore
Recruiting

Impact of A Mobile Game on Pediatric Nutrition and Physical Activity

Condition:   Pediatric Nutrition
Interventions:   Other: Fooya mobile game;   Other: Uno board game
Sponsors:   Center for Communication and Change India;   Johns Hopkins University;   Carnegie Mellon University;   Hofstra University;   FriendsLearn Inc.;   The Mithra Trust;   Mind in Motion;   Seethapathy Clinic & Hospital
Completed

Effectiveness of Diabetes Prevention Education Program on Diabetes Prevention Among Prediabetes Population in Nepal

Condition:   Prediabetic State
Interventions:   Behavioral: Diabetes Prevention Education Program;   Behavioral: Diabetes Prevention Education brochure
Sponsors:   Norwegian University of Science and Technology;   Kathmandu University School of Medical Sciences
Not yet recruiting

Global SYMPLICITY Registry

Conditions:   Hypertension;   Diabetes Mellitus;   Heart Failure;   Chronic Kidney Disease;   Sleep Apnea
Intervention:   Device: Medtronic Renal Denervation System
Sponsor:   Medtronic Vascular
Recruiting

Lifestyle Intervention Feasibility for Arrhythmia and Symptoms With Intermittent Fasting (LIFE AS IF)

Conditions:   Obesity;   Morbid Obesity;   Diabetes Mellitus, Type 2;   Atrial Fibrillation
Intervention:   Behavioral: Intermittent Fasting
Sponsor:   University of Chicago
Recruiting

StartRIGHT: A Pilot Research Study About Diabetes Diagnosis & Treatment

Condition:   Diabetes
Intervention:   Other: Optimised Diagnostic Strategy
Sponsor:   Royal Devon and Exeter NHS Foundation Trust
Terminated

Screening, Early Referral and Lifestyle Tailored E_prescription for Cardiovascular Prevention

Conditions:   Cardiovascular Diseases;   Cerebral Infarction;   Type2 Diabetes Mellitus;   Hypertension,Essential;   Prevention
Intervention:   Behavioral: SELECT mHealth Program
Sponsors:   Aga Khan University;   The George Institute
Not yet recruiting

Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy

Condition:   Diabetic Cardiomyopathies
Interventions:   Drug: AT-001;   Drug: Placebo
Sponsor:   Applied Therapeutics, Inc.
Not yet recruiting

Effect of Adding Vildagliptin vs Glimepiride to Metformin on Inflammation's Markers in Type-2 Diabetic Patients With CAD

Conditions:   Coronary Artery Disease;   Diabetes Mellitus, Type 2
Interventions:   Drug: Vildagliptin 50 mg Oral Tablet;   Drug: Metformin 1000 mg Oral Tablet;   Drug: Glimepiride 4 mg Oral Tablet
Sponsor:   Damanhour University
Active, not recruiting

Dapagliflozin in PRESERVED Ejection Fraction Heart Failure

Condition:   Chronic Heart Failure With Preserved Systolic Function
Interventions:   Drug: Dapagliflozin 10Mg Oral Tablet;   Drug: Dapagliflozin matching placebo
Sponsor:   Saint Luke's Health System
Recruiting

Empagliflozin Impact on Hemodynamics in Patients With Heart Failure

Condition:   Heart Failure
Interventions:   Drug: Empagliflozin 10Mg Tab;   Drug: Placebo Oral Tablet
Sponsor:   Saint Luke's Health System
Recruiting

Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure

Condition:   Chronic Heart Failure With Reduced Systolic Function
Interventions:   Drug: Dapagliflozin;   Drug: Dapagliflozin matching placebo
Sponsor:   Saint Luke's Health System
Active, not recruiting

Family Investigation of Nephropathy and Diabetes (F.I.N.D.)

Conditions:   Diabetic Nephropathy;   Diabetes Mellitus;   Diabetic Kidney Disease;   Albuminuria
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Multicenter Assessment of the Pancreas in Type 1 Diabetes

Condition:   Diabetes Mellitus
Intervention:   Other: Non-contrast magnetic resonance imaging
Sponsors:   Vanderbilt University Medical Center;   University of Texas at Austin;   University of Chicago;   University of Colorado, Denver;   St. Vincent's Institute of Medical Research;   Juvenile Diabetes Research Foundation
Recruiting

Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer

Conditions:   Pre-Eclampsia;   Frozen Embryo Transfer
Intervention:   Procedure: FROZEN EMBRYO TRANSFER IN SUBSTITUTED CYCLE
Sponsors:   Instituto Valenciano de Infertilidad, IVI VALENCIA;   IVI Bilbao;   IVI Barcelona;   IVI Madrid;   IVI Sevilla;   IVI Vigo;   IVI Roma;   Hospital Universitario La Paz
Recruiting

Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes

Conditions:   Body Weight;   Obesity;   Overweight and Obesity;   Obesity, Abdominal;   Hypertension;   Hyperlipidemias;   Cardiovascular Diseases;   Coronary Heart Disease;   Stroke;   Mortality;   Dyslipidemias;   Diabetes;   PreDiabetes;   Insulin Tolerance;   Dysglycemia;   Metabolic Syndrome
Intervention:   Other: Nordic diet
Sponsors:   University of Toronto;   Canadian Institutes of Health Research (CIHR);   Canada Research Chairs Endowment of the Federal Government of Canada;   The Physicians' Services Incorporated Foundation;   Canadian Diabetes Association
Active, not recruiting

Multicenter ESG Trial (MERIT Trial)

Conditions:   Obesity;   Hypertension;   Diabetes Mellitus, Type 2
Intervention:   Device: Overstitch
Sponsors:   Mayo Clinic;   University of Texas;   Johns Hopkins University;   Brigham and Women's Hospital;   NorthShore University HealthSystem;   University of Chicago;   Orlando Health, Inc.;   Cornell University;   Avera McKennan Hospital & University Health Center
Active, not recruiting

Monogenic Diabetes Misdiagnosed as Type 1

Conditions:   Diabetes Mellitus, Type 1;   Monogenic Diabetes;   Neonatal Diabetes;   Maturity-onset Diabetes in the Young (MODY);   Wolfram Syndrome;   Wolcott-Rallison Syndrome;   Mitochondrial Diabetes
Intervention:  
Sponsor:   Constantin Polychronakos
Not yet recruiting

Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or Obesity

Conditions:   Overweight;   Obesity
Interventions:   Drug: Semaglutide;   Drug: Placebo (semaglutide);   Drug: Liraglutide;   Drug: Placebo (liraglutide)
Sponsor:   Novo Nordisk A/S
Recruiting

Fibrillary w/ ACTH Therapy

Conditions:   Renal Disease;   Fibrillary Glomerulopathy
Interventions:   Drug: Acthar 80 UNT/ML Injectable Solution;   Drug: Tacrolimus capsule
Sponsors:   NephroNet, Inc.;   Mallinckrodt
Recruiting

Lifestyle Intervention Plus Emotion Regulation Group Intervention Impact on Women's Cardiovascular Risk Reduction

Conditions:   Cardiovascular Diseases;   Lifestyle Risk Reduction
Intervention:   Behavioral: Lifestyle Plus Emotional Regulation
Sponsor:   Hadassah Medical Organization
Enrolling by invitation