Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

The Effect of Cardiac Educational Program on Level of Knowledge and Satisfaction Among Coronary Artery Disease Patients in North of Jordan

Condition:   Coronary Artery Disease
Intervention:   Other: cardiac educational program
Sponsor:   Jordan University of Science and Technology
Recruiting

Physiological Patterns of Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Diagnostic Test: Fractional Flow Reserve Motorized Pullback
Sponsor:   Onze Lieve Vrouw Hospital
Completed

Blood Pressure Responses to Different Exercise Modes in Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Other: exercise
Sponsor:   National Taiwan University Hospital
Enrolling by invitation

Combined Use of Multiple Biomarkers With Stress Testing to Detect Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Active, not recruiting

Study of the Effect of Diabetes on the Incidence and the Extent of Coronary Artery Disease

Condition:   Patients Undergoing Coronary Angiography
Intervention:  
Sponsors:   University of Ioannina;   University Hospital, Ioannina;   Catheterization Laboratory of 1st IKA Hospital, Athens
Completed

Fear of Activity and Functional Capacity in Patients With Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Combination Product: Modified Bruce protocol on treadmill
Sponsor:   Hitit University
Completed

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

Conditions:   Cardiovascular Diseases;   End Stage Renal Disease;   Kidney Transplantation;   Dialysis Related Complication
Interventions:   Other: No screening;   Other: Regular Screening
Sponsors:   University of British Columbia;   University of Sydney
Recruiting

Effects of Egg Ingestion on Endothelial Function in Adults With Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Dietary Supplement: Egg supplementation;   Dietary Supplement: Egg substitute;   Dietary Supplement: Control diet
Sponsors:   Griffin Hospital;   American Egg Board
Completed

Effect of Long-term Exercise on Haemostasis and Inflammation in Patients With Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Exercise;   Inflammation;   Hemostasis
Intervention:   Other: Long-term exercise
Sponsors:   Aarhus University Hospital;   National Hospital of the Faroe Islands
Not yet recruiting

Polymorphisms in CD36 and STAT3 Genes and Different Dietary Interventions Among Patients With Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Dietary Supplement: Olive oil;   Dietary Supplement: Nuts;   Dietary Supplement: Control diet
Sponsors:   Instituto de Cardiologia do Rio Grande do Sul;   Conselho Nacional de Desenvolvimento Científico e Tecnológico;   Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil
Active, not recruiting

Multicenter Study to Evaluate the Procedural Safety and Efficacy of ELCA in CAD

Condition:   Coronary Artery Disease
Intervention:   Device: Excimer Laser Coronary Atherectomy
Sponsors:   Spectranetics Corporation;   CBCC-VIBGYOR Research Pvt. Ltd.
Completed

Effects of dapaglifloziN Therapy on Myocardial Perfusion Reserve in Prediabetic Patients With Stable coronarY Artery Disease

Conditions:   Coronary Artery Disease;   Prediabetic State
Interventions:   Drug: Dapagliflozin 10mg;   Other: Lifestyle modification
Sponsor:   CHEOL WHAN LEE, M.D., Ph.D
Not yet recruiting

Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia

Conditions:   Coronary Artery Disease;   Angina, Stable;   Exercise Test;   Biological Markers;   SPECT
Intervention:  
Sponsor:   University Hospital, Basel, Switzerland
Active, not recruiting

Cardiac MRI in Front Line for the Diagnosis of Coronary Artery Disease as the Etiology of Left Ventricular Dysfunction

Condition:   Ischemic Cardiomyopathy
Intervention:  
Sponsor:   Assistance Publique - Hôpitaux de Paris
Suspended

Comparison of the Severity of Coronary Atherosclerosis With Tissue Compliance in Patients Within First Degree Relatives

Condition:   Coronary Artery Disease With Myocardial Infarction
Intervention:   Diagnostic Test: there is not any intervention procedure
Sponsor:   TC Erciyes University
Not yet recruiting

Validation of a Single Rest-Stress Imaging Protocol for Myocardial Perfusion Imaging

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:   Diagnostic Test: Single-Scan Two-Injection Protocol
Sponsor:   Massachusetts General Hospital
Recruiting

Effect of Empagliflozin on Ventricular Repolarization.

Conditions:   Diabetes Mellitus, Type 2;   Coronary Heart Disease;   Arrythmia, Cardiac
Intervention:   Drug: Empagliflozin 25 MG
Sponsor:   University of Sao Paulo
Recruiting

Hyperoxia and Microvascular Dysfunction

Conditions:   Coronary Microvascular Disease;   Microvascular Disease;   Ischemic Heart Disease
Interventions:   Other: Hyperoxia;   Other: Normoxia;   Device: laser Doppler
Sponsor:   Université Libre de Bruxelles
Terminated

Transepicardial With Transseptal Autologous CD 133+ Bone Marrow Cell Implantation in Patient Following CABG Surgery

Condition:   Coronary Artery Disease
Intervention:   Biological: Transepicardial with Transseptal CD 133+ Implantation
Sponsor:   National Cardiovascular Center Harapan Kita Hospital Indonesia
Completed

Coroflex ISAR NEO "All Comers" Post Market Clinical Follow-up (PMCF)

Condition:   Coronary Artery Disease
Intervention:   Device: Coroflex® ISAR NEO coronary stent system
Sponsor:   B. Braun Melsungen AG
Recruiting

The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: MICS CABG;   Procedure: Conventional CABG
Sponsors:   Ottawa Heart Institute Research Corporation;   London Health Sciences Centre;   Heart Center Leipzig - University Hospital;   Fortis Escorts Heart Institute;   The Methodist Hospital System;   Carolinas Medical Center;   Gundersen Lutheran Health System;   Jilin Heart Hospital;   Far Eastern Memorial Hospital;   Medtronic;   Apollo Hospitals;   Ichinomiya-Nishi Hospital;   Fresno Heart and Surgical Hospital
Active, not recruiting

Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19

Conditions:   Angina Pectoris;   Acute Coronary Syndrome;   Coronary Syndrome;   Coronary Artery Disease;   Angioplasty;   Stent Restenosis;   Hypertension;   Heart Failure, Systolic;   Depression, Anxiety;   Covid-19;   Isolation, Social
Intervention:   Other: Tele-medicine platform
Sponsors:   Professor Adrian Covic;   Medical Sciences Academy - Romania;   Victor Babes Clinical Hospital of Infectious Diseases - Bucharest
Recruiting

The Genomic Medicine at VA Study

Conditions:   Coronary Artery Disease;   Atrial Fibrillation;   Type 2 Diabetes;   Colorectal Cancer;   Breast Cancer;   Prostate Cancer
Intervention:   Diagnostic Test: Polygenic risk score (PRS)
Sponsors:   Harvard Medical School;   VA Boston Healthcare System
Not yet recruiting

Registry on Left Main Coronary Artery Bifurcation Percutaneous Intervention

Conditions:   Coronary Arteriosclerosis;   Left Main Coronary Artery Disease
Intervention:   Procedure: PCI on left main
Sponsors:   G. d'Annunzio University;   Azienda Sanitaria Locale n. 2 - Lanciano Vasto Chieti;   Hospital Clínico Universitario de Valladolid;   VZW Cardiovascular Research Center Aalst;   Federico II University;   Fondazione Policlinico Universitario Agostino Gemelli IRCCS;   Clinica Mediterranea;   Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland;   San Raffaele University Hospital, Italy;   Instituto Dante Pazzanese de Cardiologia;   University Medical Centre Maribor;   Clinica Di Montevergine;   Clinical Hospital Centre Zagreb;   Clinical Centre of Serbia;   Chiba University;   Université Paris-Sud;   Hospital Universitario Reina Sofia de Cordoba;   Mount Sinai Hospital, New York;   Hospital Pablo Tobón Uribe;   Pauls Stradins Clinical University Hospital;   University Hospital Monastir, Tunis
Not yet recruiting

Coronary Physiology and Its Relationship to Anatomy in Patients With Diabetes Mellitus

Conditions:   Diabetes Mellitus;   Coronary Artery Disease
Intervention:   Device: Pressure Wire Certus, St. Jude Medical, USA
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

Condition:   Coronary Heart Disease (CHD)
Interventions:   Drug: Evolocumab;   Drug: Placebo
Sponsor:   Amgen
Recruiting

Study to Learn More About the Effectiveness and Safety of Rivaroxaban (Xarelto) When Given Together With Acetylsalicylic Acid to Patients Suffering From a Condition That Affects the Blood Vessels Supplying the Heart (CAD) and/or a Condition That Affects the Blood Vessel of the Lower Limbs (PAD).

Conditions:   Coronary Artery Disease(CAD);   Peripheral Artery Disease(PAD)
Interventions:   Drug: Rivaroxaban (Xarelto,Bay 59-7939);   Drug: Acetylsalicylic acid(ASA)
Sponsor:   Bayer
Not yet recruiting

Bioflow-DAPT Study

Condition:   Coronary Artery Disease
Intervention:   Device: Percutaneous coronary intervention
Sponsor:   Biotronik AG
Recruiting

Quantitative Coronary Angiography Versus Intravascular Ultrasound GUIDancE for Drug-Eluting Stent Implantation

Conditions:   Coronary Disease;   Coronary Stenoses
Interventions:   Device: quantitative coronary angiography guided coronary intervention with sirolimus-eluting Orsiro stent;   Device: intravascular ultrasound guided coronary intervention with sirolimus-eluting Orsiro stent
Sponsors:   CHEOL WHAN LEE, M.D., Ph.D;   Biotronik SE & Co. KG
Recruiting

A Single Arm Trial With Resolute Onyx in ONE-Month DAPT for High-Bleeding Risk Patients Who Are Considered One-Month Clear (Onyx ONE Clear)

Condition:   Coronary Artery Disease
Intervention:   Combination Product: Device: Medtronic Resolute Onyx Zotarolimus-Eluting Coronary Stent System Treatment Followed by one-month DAPT
Sponsor:   Medtronic Vascular
Active, not recruiting

RESOLUTE ONYX Post-Approval Study (Bifurcation Cohort)

Condition:   Coronary Artery Disease
Intervention:   Device: Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
Sponsor:   Medtronic Vascular
Active, not recruiting

A Clinical Trial to Assess the SYNERGY 48 mm Stent System for the Treatment of Atherosclerotic Lesion(s)

Condition:   Coronary Artery Disease
Intervention:   Device: SYNERGY 48 mm
Sponsor:   Boston Scientific Corporation
Active, not recruiting

Serial OCT Evaluation of Tissue Coverage in Patients Submitted to Inspiron Drug Eluting Stent Implantation

Condition:   Coronary Artery Disease
Intervention:   Device: Angiography and Optical Coherence Tomography evaluations
Sponsor:   Scitech Produtos Medicos Ltda
Active, not recruiting

RESOLUTE ONYX Post-Approval Study

Condition:   Coronary Artery Disease
Intervention:   Device: Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
Sponsor:   Medtronic Vascular
Active, not recruiting

Medtronic RevElution Trial

Condition:   Coronary Artery Disease
Intervention:   Device: Polymer-free DES (Drug Eluting Stent)
Sponsor:   Medtronic Vascular
Active, not recruiting

Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Interventions:   Drug: N-acetyl cysteine;   Drug: Saline
Sponsor:   Suleyman Demirel University
Active, not recruiting

Local Thrombolytics Before Thrombectomy in STEMI

Condition:   Coronary Artery Disease
Interventions:   Drug: Urokinase;   Drug: Saline
Sponsor:   University of Roma La Sapienza
Enrolling by invitation

A Study to Assess the Amount of Drug Levels in Blood and Safety of AZD5718 Formulations in Healthy Volunteers

Condition:   Coronary Artery Disease (CAD)
Interventions:   Drug: AZD5718 tablet, Formulation A;   Drug: AZD5718 tablet, Formulation B;   Drug: AZD5718 tablet, Formulation C;   Drug: AZD5718 tablet, Formulation D;   Drug: AZD5718 film-coated tablet, Reference treatment
Sponsors:   AstraZeneca;   Parexel
Completed

Coroflex ISAR 2000 Extended Registry (ISAR2000 Extended)

Condition:   Coronary Artery Disease (CAD)
Intervention:   Device: stenting with the Coroflex ISAR sirolimus-eluting stent
Sponsors:   B. Braun Melsungen AG;   Charite University, Berlin, Germany
Active, not recruiting

Post Market Surveillance of SeQuent Please Neo With Scoring Balloon

Condition:   Coronary Artery Disease (CAD)
Intervention:   Device: Drug Coated Balloon Angioplasty, Scoring Balloon Dilatation
Sponsors:   B. Braun Melsungen AG;   Klinikum Ernst von Bergmann Augenklinik Laserzentrum
Completed

Optimal Timing of Transcatheter Aortic Valve Implantation and Percutaneous Coronary Intervention - The TAVI PCI Trial

Conditions:   Aortic Stenosis;   Coronary Artery Disease;   TAVI;   PCI
Interventions:   Procedure: PCI before TAVI;   Procedure: PCI after TAVI
Sponsor:   University of Zurich
Not yet recruiting

Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

Condition:   Sickle Cell Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Mer-TK in Human Cardiac Cells

Conditions:   Myocardial Inflammation;   Myocardial Infarction
Intervention:   Other: Change in Soluble MER Concentration
Sponsor:   Ann & Robert H Lurie Children's Hospital of Chicago
Active, not recruiting

A Clinical Trial to Confirm Safety & Effectiveness of the SYNERGY 4.50 mm and 5.00 mm Stent for Treatment of Atherosclerotic Lesion(s)

Conditions:   Atherosclerosis;   Heart Diseases, Coronary;   Coronary Artery Disease;   Cardiovascular Diseases
Intervention:   Device: SYNERGY 4.50 mm and 5.0 mm Coronary Stent System
Sponsor:   Boston Scientific Corporation
Recruiting

EXCEL Clinical Trial

Conditions:   Chronic Coronary Occlusion;   Unprotected Left Main Coronary Artery Disease;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Interventions:   Device: Percutaneous Coronary Intervention;   Procedure: CABG
Sponsor:   Abbott Medical Devices
Completed

Study to Gain Insights in Treatment Patterns and Outcomes in Patients With Atherosclerosis Prescribed to Xarelto in Combination With Acetylsalicylic Acid

Condition:   Atherosclerosis
Interventions:   Drug: Rivaroxaban (BAY59-7939, Xarelto);   Drug: Acetylsalicylic acid
Sponsors:   Bayer;   Janssen, LP
Recruiting

Sleep-disordered Breathing and Perioperative Atrial Fibrillation in Cardiac Surgery

Conditions:   Elective Coronary Artery Bypass Grafting (CABG) Surgery;   Coronary Artery Disease;   Sleep-disordered Breathing (SDB);   Atrial Fibrillation
Intervention:   Other: Stratification, no intervention
Sponsor:   Michael Arzt
Recruiting

The Effect Of An Expanded Long Term Periodization Exercise Training In Patients With Cardiovascular Disease

Conditions:   Cardiovascular Diseases;   Coronary Artery Disease
Interventions:   Other: Periodized Exercise Training Regime;   Other: Non Periodized Exercise Training Regime
Sponsor:   University of Lisbon
Completed

Short Interval Resveratrol Trial in Cardiovascular Surgery

Conditions:   Diabetes Mellitus, Type 2;   Coronary Artery Disease
Interventions:   Dietary Supplement: Trans-resveratrol;   Dietary Supplement: Placebo
Sponsors:   Maine Medical Center;   American Heart Association
Recruiting

Evaluating a New Echocardiography Imaging Procedure for Evaluating Heart Function

Conditions:   Ischemia;   Myocardial Infarction;   Ischemic Heart Disease
Intervention:  
Sponsors:   Yale University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Arm Exercise Versus Pharmacologic Stress Testing for Clinical Outcome

Condition:   Veterans Referred to the St. Louis VAMC Stress Tes
Interventions:   Procedure: Regadenoson myocardial perfusion imaging stress test;   Procedure: Arm exercise electrocardiographic stress test;   Procedure: Treadmill electrocardiographic stress test;   Procedure: Coronary artery calcium score and cardiac computed tomographic angiography
Sponsors:   VA Office of Research and Development;   VA St. Louis Health Care System
Active, not recruiting

Electronic Activity Tracking System (EATs)

Condition:   Coronary Heart Disease
Interventions:   Device: Fitness tracker;   Device: Auto-feedback/ reminder;   Procedure: Standard care
Sponsor:   University of Malaya
Not yet recruiting

The Comparison of Strategies to PREPARE Severely CALCified Coronary Lesions Trial (PREPARE-CALC)

Condition:   Coronary Atherosclerosis Due to Severely Calcified Coronary Lesion
Interventions:   Device: Rotational Atherectomy;   Device: Cutting/Scoring Balloon
Sponsor:   Segeberger Kliniken GmbH
Completed

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Conditions:   Coronary Artery Disease;   Ischemic Heart Disease;   Non ST Segment Elevation Myocardial Infarction
Interventions:   Device: Orbital Atherectomy;   Device: Balloon
Sponsors:   Cardiovascular Systems Inc;   Cardiovascular Research Foundation, New York
Recruiting

The Recovery of Cardiovascular Patients With Depression

Conditions:   Coronary Artery Disease;   Depression;   Cardiovascular Diseases
Interventions:   Drug: Psychiatric treatment with sertraline;   Drug: Psychiatric treatment with escitalopram
Sponsor:   Klinički Bolnički Centar Zagreb
Recruiting

HIV-HEART Aging Study (15 Year Follow up)

Conditions:   HIV Infections;   Coronary Disease;   Myocardial Infarction;   HIV Encephalopathy;   Aging;   Heart Failure;   Weight Gain
Intervention:  
Sponsor:   University Hospital, Essen
Not yet recruiting

MULTivessel Immediate Versus STAged RevaScularization in Acute Myocardial Infarction -The MULTISTARS AMI Trial

Conditions:   ST-elevation Myocardial Infarction;   Multivessel Coronary Disease
Interventions:   Procedure: Staged complete PCI;   Procedure: Immediate complete PCI;   Device: Synergy™ stent
Sponsor:   University of Zurich
Recruiting

Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis

Condition:   Psoriasis
Interventions:   Drug: etanercept;   Drug: ustekinumab;   Drug: cyclosporine;   Drug: Secukinumab;   Drug: Apremilast
Sponsor:   University of Athens
Recruiting

Educational Model for Cardiac Patients

Conditions:   Coronary Artery Disease;   Coronary Disease;   Arteriosclerosis;   Cardiovascular Diseases
Interventions:   Behavioral: educational model + follow up;   Behavioral: usual care
Sponsor:   University of Sao Paulo
Completed

Peer Support for Women With Heart Disease: Women@Heart

Conditions:   Coronary Heart Disease;   Women's Health
Intervention:   Behavioral: Women@Heart Program
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting

Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI

Conditions:   Obstructive Sleep Apnea;   Diabetes Mellitus;   Coronary Artery Disease
Intervention:  
Sponsors:   National University, Singapore;   National Heart Centre Singapore
Completed

E-health Intervention for Cardiac Rehabilitation

Conditions:   Coronary Heart Disease;   Valve Disease, Heart
Interventions:   Behavioral: Virtual Cardiac Rehabilitation Program;   Behavioral: Case Managed Home Program
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting

Chronic Total Occlusion Percutaneous Coronary Intervention Study

Conditions:   Chronic Total Occlusion;   Ischemic Heart Disease;   Chronic Total Occlusion of Coronary Artery
Interventions:   Procedure: Chronic Total Occlusion Revascularization;   Device: GuideLiner® V3 catheter, TrapLiner® catheter, Turnpike® catheter
Sponsors:   Vascular Solutions, Inc;   Teleflex;   Bright Research Partners
Active, not recruiting

The Effect of Remote Ischemic Preconditioning in Aortic Valve Replacement Surgery

Conditions:   Aortic Valve Stenosis;   Cardiopulmonary Bypass
Intervention:   Procedure: Blood pressure cuff inflation
Sponsors:   Laval University;   Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Active, not recruiting

Undiagnosed Sleep Apnea and Bypass OperaTion

Condition:   Sleep Apnea
Intervention:  
Sponsor:   National University, Singapore
Completed

Evaluation of the Potential Impact of Computerized Antimicrobial Stewardship

Conditions:   Antimicrobial Stewardship;   Cardiovascular Surgeries;   Computerized Decision Support System;   Coronary Artery Disease;   Valve Heart Disease
Intervention:   Other: Computer based Antimicrobial stewardship (AMS) intervention system
Sponsor:   China National Center for Cardiovascular Diseases
Not yet recruiting

Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion

Condition:   Radial Artery Occlusion
Intervention:   Drug: Rivaroxaban 15 MG Oral Tablet [Xarelto]
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting

The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS)

Condition:   ASCVD
Intervention:  
Sponsors:   Amgen;   Duke Clinical Research Institute
Recruiting

Impact of Preoperative FFR on Arterial Bypass Graft Functionality

Condition:   Heart Disease
Intervention:   Procedure: Fractional Flow Reserve (FFR)
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting

Effects of Functional Electrical Stimulation in Patients Undergoing Coronary Artery Bypass Grafting Surgery

Condition:   Muscle Wasting
Interventions:   Device: Functional Electrical Stimulation (FES);   Other: Functional Electrical Stimulation (FES) sham
Sponsor:   Universidade Federal de Santa Maria
Completed

Prospective Treatment Algorithm Guiding Repair of Severe Ischemic Mitral Regurgitation

Condition:   Mitral Regurgitation
Interventions:   Procedure: Treatment Algorithm;   Procedure: No Treatment Algorithm
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting

Impact of Covid-19 in Congenital Heart Disease

Conditions:   Congenital Heart Disease;   Covid-19
Intervention:  
Sponsors:   University Hospital, Montpellier;   Pr. Jean-Benoît THAMBO, Bordeaux (président);   Dr. Céline GRUNENWALD GRONIER, Strasbourg;   Dr. Sébastien HASCOET, Le Plessis-Robinson;   Dr. Adeline BASQUIN, Rennes;   Dr. Nicolas COMBES, Toulouse;   Dr. Xavier IRIART, Bordeaux;   Dr. Daniela LAUX, Paris;   Dr. Magalie LADOUCEUR, Paris;   Pr. BERTRAND LEOBON, Toulouse;   Pr. Caroline OVAERT, Marseille;   Dr. Karine WARIN-FRESSE, Nantes;   Alexis BLANC, Montpellier
Recruiting

Identification of High-Risk Patients at Admission to an Emergency Department by Non-Invasive Hemodynamics

Conditions:   Emergency Department Triage;   Non-invasive Hemodynamic
Intervention:   Device: Finapres Nova
Sponsors:   University Hospital Bispebjerg and Frederiksberg;   Doctor Sofus Carl Emil Friis and Mrs Olga Doris Friss' Fund
Recruiting

Boston Puerto Rican Health Study

Condition:   Cardiovascular Risk Factor
Intervention:   Behavioral: The Heart Healthy Initiative for Hispanic Adults (HIP)
Sponsors:   University of Massachusetts, Lowell;   National Heart, Lung, and Blood Institute (NHLBI);   National Institute on Aging (NIA);   Tufts University;   Northeastern University
Completed

The Effect of High-Intensity Interval Training on Glucose Variability and Atrial Fibrillation Symptoms

Conditions:   Atrial Fibrillation;   Type 2 Diabetes
Intervention:   Behavioral: High-intensity interval training + standard care
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting

Frailty in Elderly Patients Receiving Surgical or Percutaneous Procedures for Valvular Disorders

Conditions:   Age Problem;   Aortic Valve Disease;   Mitral Valve Disease
Intervention:   Other: frailty evaluation
Sponsors:   University Hospital of Ferrara;   Maria Cecilia Hospital
Recruiting

Prospective European Multicenter Study on Aortic Valve Replacement: (E-AVR Registry)

Conditions:   Aortic Valve Stenosis;   Valve Heart Stenosis
Intervention:   Procedure: Aortic valve replacement
Sponsors:   University of Parma;   University of Genova;   University Hospitals, Leicester;   University of Hamburg;   San Camillo Hospital, Rome;   University of Turin, Italy;   Centre Hospitalier Universitaire de Besancon;   University Hospital, Udine, Italy;   Hospital Clinic of Barcelona;   University of Lausanne Hospitals;   Robert Debré Hospital;   Paracelsus Medical University;   University of Campania "Luigi Vanvitelli";   University of Texas, Southwestern Medical Center at Dallas;   Clinique Pasteur;   Cardiocentro Ticino;   Universita di Verona
Recruiting

Optimizing Statin Tratment

Condition:   Diabetes
Intervention:  
Sponsor:   University Hospital, Montpellier
Active, not recruiting

Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS

Conditions:   Aortic Valve Stenosis;   Hypertrophy, Left Ventricular
Intervention:   Procedure: Aortic valve intervention
Sponsors:   University of Edinburgh;   Sir Jules Thorn Charitable Trust
Recruiting

A New Hormone Replacement Paradigm: Physiologic Restoration Study

Conditions:   Menopause;   Perimenopausal Disorder;   Menopause Related Conditions
Intervention:   Biological: Compounded topical estradiol and compounded topical progesterone in a carrier cream
Sponsor:   Women's Hormone Network
Not yet recruiting

Subclinical Cardiac Involvement in Patients With Inflamatory Bowel Disease

Condition:   Inflammatory Bowel Diseases
Intervention:   Device: ECG, HolterECG ,Echocardiography
Sponsor:   Hossam Eldin Mohammed Essam Abdelhafez
Not yet recruiting

Triple or Dual Antithrombotic Therapy After PCI (TRIDUAL-PCI) Coronary Intervention in Patients With Non-valvular Atrial Fibrillation. Real-world Italian Multicenter Registry (TRIDUAL-PCI)

Conditions:   Atrial Fibrillation;   Myocardial Infarction;   Anticoagulant-induced Bleeding;   Coronary Disease
Intervention:   Drug: Antithrombotic Agent
Sponsor:   Scientific Institute San Raffaele
Recruiting

Levosimendan for Veno-arterial ECMO Weaning

Conditions:   Cardiogenic Shock;   Refractory Shock
Interventions:   Other: Data collection;   Other: Data analysis
Sponsor:   Hospices Civils de Lyon
Completed

The Efficacy of Cholesterol-lowering Probiotic Lactobacillus Plantarum LPLDL® in Hypercholesterolemic Adults.

Condition:   Hypercholesterolemia
Interventions:   Dietary Supplement: Lactobacillus plantarum ECGC 13110402;   Dietary Supplement: Placebo Comparator: Maltodextrin
Sponsor:   University of Roehampton
Active, not recruiting

Prognostic Factors Keeping Track for Covid19 Pneumonia

Conditions:   Pneumonia, Viral;   Hypertension;   Diabetes Mellitus;   Obesity;   Cardiovascular Diseases;   Obstructive Lung Disease
Intervention:  
Sponsor:   Catholic University of the Sacred Heart
Recruiting

Biomarkes Of Job STRess In Emergency Senior Physicians - Detection of Stressful Events

Condition:   Heart Rate Variability
Intervention:   Behavioral: Comparison of biomarkers of stress
Sponsor:   University Hospital, Clermont-Ferrand
Not yet recruiting

Arrhythmic Risk Stratification in Nonischemic Dilated Cardiomyopathy

Conditions:   Sudden Cardiac Death Due to Cardiac Arrhythmia;   Dilated Cardiomyopathy
Intervention:   Device: Implantable Cardioverter Defibrillator (ICD) insertion
Sponsor:   University of Athens
Not yet recruiting

6-Session Treatment for Generalized Anxiety Disorder

Condition:   Generalized Anxiety Disorder
Intervention:   Behavioral: Behavioural experiments for intolerance of uncertainty (BE-IU)
Sponsors:   Universite du Quebec en Outaouais;   Canadian Institutes of Health Research (CIHR);   Concordia University, Montreal;   University College, London
Active, not recruiting

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Conditions:   Diabetes Mellitus;   Chronic Kidney Diseases;   Heart Diseases;   Cardiovascular Diseases
Intervention:  
Sponsors:   University of New Mexico;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)-Phoenix Epidemiology and Clinical Research;   Zuni Pueblo;   Urban Albuquerque Area American Indians seen at First Nations Hospital
Not yet recruiting

Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury

Condition:   Contrast-induced Acute Kidney Injury
Interventions:   Device: RIPC;   Device: Sham-RIPC
Sponsors:   Oladipupo Olafiranye, MD, MS;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Gamification to Increase Mobility in the Hospital

Conditions:   Coronary Artery Disease;   Coronary Heart Disease;   Hypertension;   Diabete Mellitus;   Dyslipidemias;   Obesity;   Heart Failure
Intervention:   Behavioral: Gamification Intervention
Sponsor:   University of Pennsylvania
Not yet recruiting

A Genomic Approach for Clopidogrel in Caribbean Hispanics

Conditions:   Cardiovascular Disease (CVD);   Stroke;   Acute Coronary Syndrome;   Peripheral Arterial Disease;   Coronary Artery Disease;   Myocardial Infarction
Interventions:   Genetic: CYP2C19 test;   Diagnostic Test: P2RY12 assay
Sponsors:   University of Puerto Rico;   National Institute on Minority Health and Health Disparities (NIMHD);   Icahn School of Medicine at Mount Sinai
Recruiting

Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)

Conditions:   Diabetic Foot Ulcer;   Coronary Artery Disease;   Parenchymatous; Pneumonia;   Kidney Stone;   Inner Ear Disease;   Brain Stroke;   Joint Diseases;   Diabetes;   Adrenal Incidentaloma;   Hyperaldosteronism;   Macroadenoma;   Interstitial Lung Disease;   Intracranial Arteriovenous Malformations
Interventions:   Device: Spectral Photon Counting Computed Tomography (SPCCT);   Device: DECT (Dual Energy CT)
Sponsor:   Hospices Civils de Lyon
Not yet recruiting

Meta-analysis of Fish Oil Supplementation and Cardiovascular Outcomes in Diabetes

Conditions:   Type2 Diabetes;   Heart Failure;   Myocardial Infarction;   Stroke;   Arrhythmia;   Cardiovascular Diseases
Intervention:   Dietary Supplement: fish oil supplement
Sponsors:   University of Toronto;   Diabetes and Nutrition Study Group (DNSG) of the European Association for the Study of Diabetes (EASD);   Canadian Institutes of Health Research (CIHR);   Diabetes Canada
Active, not recruiting

Technical Development of Cardiovascular Magnetic Resonance Imaging

Conditions:   Cardiomyopathy;   Congenital Heart Disease;   Cardiovascular Disease;   Cardiac Magnetic Resonance Imaging;   Acute Myocardial Infarction
Intervention:   Device: Siemens MRI scanner
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Suspended

Efficacy of a High-intensity Physical Activity Program on Renal Function in High Risk Patients With Type 2 Diabetes

Conditions:   Type2 Diabetes;   Diabetic Kidney Disease
Interventions:   Other: HIPA;   Other: Counseling PA
Sponsors:   Poitiers University Hospital;   University Hospital, Bordeaux;   University Hospital, Clermont-Ferrand;   Centre Hospitalier Universitaire Dijon;   Centre Hospitalier Universitaire de Besancon;   Hopital Lariboisière;   Bichat Hospital;   Centre Hospitalier Sud Francilien;   University Hospital, Lille;   Centre Hospitalier Universitaire de Nice;   University Hospital, Caen;   University Hospital, Toulouse;   University Hospital, Tours;   Nantes University Hospital;   Groupe Hospitalier Pitie-Salpetriere;   Hospices Civils de Lyon;   University Hospital, Montpellier;   University Hospital, Strasbourg;   Central Hospital, Nancy, France;   HOSPITAL, CHARTRES;   University of Liege
Recruiting

Evaluating the Effects of EECP on Circulation, Blood Glucose Level and Blood Pressure in Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Intervention:  
Sponsor:   David Grant U.S. Air Force Medical Center
Terminated

Randomized Endo-Vein Graft Prospective

Condition:   Coronary Artery Bypass Grafting
Intervention:   Procedure: Vein Harvesting Procedures
Sponsor:   VA Office of Research and Development
Active, not recruiting

Frailty Assessment in Cardiac Surgery

Condition:   Frailty
Intervention:  
Sponsors:   Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital;   Turkish Society of Cardiovascular Surgery
Recruiting

Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System

Conditions:   Atherosclerosis;   Chronic Granulomatous Disease (CGD)
Intervention:  
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting

Dolutegravir and Clinical Outcomes Among ART-recipients in Brazil

Conditions:   HIV Infections;   Clinical Outcomes;   Adverse Drug Event;   Effect of Drugs
Intervention:   Other: No intervention
Sponsors:   Fundação Bahiana de Infectologia;   University of New Mexico;   Instituto Infectologia Evandro Chagas, Rio de Janeiro;   Instituto de Infectologia Emilio Ribas, S. Paulo;   Instituto de Medicina Tropical de Manaus;   Hospital da Clinicas de Porto Alegre;   Centro de Referência e Tratamento, CRT, São Paulo, SP;   Universidade Federal de Minas gerais, MG);   EMESCAN, Vitória, Espírito Santo;   Hospital Partenon, Porto Alegre;   Hospital das Clinicas, Recife
Not yet recruiting

Retinol-binding Protein 4 (RBP4) Metabolizm in Type 2 Diabetes Progression and Associated Cardiovascular Complications

Condition:   Diabetes Mellitus, Type 2
Intervention:   Other: Exposure factors
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Not yet recruiting

Accelerated Rule Out of Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Procedure: Accelerated, combined biomarker rule-out strategy for MI
Sponsor:   Aarhus University Hospital Skejby
Completed

Can Vitamin D Reduce Heart Muscle Damage After Bypass Surgery?

Conditions:   Vitamin D Deficiency;   Cardiomyopathies;   Apoptosis;   Inflammation
Interventions:   Drug: Vitamin D;   Drug: Placebo
Sponsor:   Shahid Beheshti University of Medical Sciences
Completed

10-year Risk Prediction Models of Complications and Mortality of DM in Hong Kong

Conditions:   Diabetes Mellitus;   Cardiovascular Diseases;   Mortality;   Primary Health Care
Intervention:  
Sponsor:   The University of Hong Kong
Completed

Clinical, Structural and Mechanical Features in Patients With Left Bundle Branch Block.

Conditions:   Left Bundle-Branch Block;   Electrocardiographic Pattens;   Clinical Features
Intervention:  
Sponsor:   Policlinico Casilino ASL RMB
Not yet recruiting

Linking Individual Needs to Community and Clinical Services

Condition:   Chronic Disease
Intervention:   Behavioral: LINKS
Sponsors:   Abby Lohr;   Pima County Health Department;   Yuma County Health District;   El Rio Community Health Center;   Sunset Community Health Center;   Mariposa Community Health Center;   Arizona Community Health Outreach Workers Association (AzCHOW)
Completed

Preventing Cardiac Complication of COVID-19 Disease With Early Acute Coronary Syndrome Therapy: A Randomised Controlled Trial.

Condition:   COVID-19
Interventions:   Drug: Aspirin 75mg;   Drug: Clopidogrel 75mg;   Drug: Rivaroxaban 2.5 MG;   Drug: Atorvastatin 40mg;   Drug: Omeprazole 20mg
Sponsor:   Imperial College London
Not yet recruiting

Safety Evaluation of Intracoronary Infusion of Extracellular Vesicles in Patients With AMI

Condition:   Heart Attack
Intervention:   Drug: PEP in Acute Myocardial Infarction
Sponsor:   Paul G. Stalboerger
Not yet recruiting

Comparison of Abdominal Aortic Aneurysm Growth in Adult Smoking Patients Who Either Switch to IQOS, Continue Smoking, or Quit Smoking.

Conditions:   Smoking;   Abdominal Aortic Aneurysm;   IQOS Use
Interventions:   Other: IQOS;   Other: Cigarette;   Other: Smoking Cessation
Sponsor:   Philip Morris Products S.A.
Recruiting

Efficacy and Safety of Tocilizumab in the Treatment of SARS-Cov-2 Related Pneumonia

Condition:   COVID-19 Pneumonia
Intervention:  
Sponsor:   University of L'Aquila
Not yet recruiting

Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk Patients

Condition:   Cardiovascular Risk Factor
Interventions:   Drug: Levosimendan;   Drug: Placebo
Sponsor:   Medical University of Vienna
Not yet recruiting

Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to Everolimus/Reduced Tacrolimus in Renal Transplant Recipients Following Campath® Induction

Condition:   Renal Transplant
Intervention:   Drug: Arm 1 Everolimus/Reduced dose tacrolimus
Sponsors:   University of Toledo Health Science Campus;   Novartis Pharmaceuticals
Active, not recruiting

SELUTION SLR™ 014 In-stent Restenosis

Condition:   Coronary Restenosis
Interventions:   Device: SELUTION SLR™ DEB;   Device: Control
Sponsors:   M.A. Med Alliance S.A.;   Genae;   Baim Institute for Clinical Research
Not yet recruiting

Respiratory Virus Infections in Acutely Hospitalized Adult Patients With Pulmonary and Extrapulmonary Complications

Conditions:   Respiratory Virus Infection;   Stroke;   Lung Disease;   Acute Coronary Syndrome
Intervention:   Diagnostic Test: Respiratory virus testing
Sponsor:   The University of Hong Kong
Recruiting

Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

Conditions:   Myocardial Infarction;   Stroke, Ischemic;   Ischemia
Intervention:   Other: There is no intervention given to the subjects
Sponsor:   UConn Health
Recruiting

Quantitative Fractional Ratio-guided Revascularization in STEMI Patients With Multi-vessel Disease

Conditions:   ST Elevation Myocardial Infarction;   Multi-Vessel Coronary Artery Stenosis
Intervention:   Procedure: PCI
Sponsors:   Fujian Medical University;   Pulse Medical Imaging Technology (Shanghai) Co., Ltd
Enrolling by invitation

Estrogen Exposure and Atherosclerosis in Postmenopausal Women

Conditions:   Atherosclerosis;   Menopause;   Estrogens;   Carotid Intima-media Thickness;   Coronary Stenoses;   Women
Intervention:  
Sponsor:   University of Valencia
Completed

Hypoglycaemia and Cardiac Arrhythmias in Type 2 Diabetes

Conditions:   Diabetes Mellitus, Type 2;   Arrhythmia, Cardiac
Interventions:   Other: Combined hyper- and hypoglycaemic clamp;   Device: Loop recorder (Reveal LINQ, Medtronic, Minneapolis, MN, USA);   Device: Continuous glucose monitoring (iPro2, Medtronic, Minneapolis, MN, USA)
Sponsor:   University Hospital, Gentofte, Copenhagen
Enrolling by invitation

Postmastecomy Internal Mammary Nodal Irradiation for High-risk Breast Cancer Patients

Condition:   Breast Cancer
Interventions:   Radiation: internal mammary nodal irradiation;   Radiation: no internal mammary nodal irradiation
Sponsors:   Chinese Academy of Medical Sciences;   Hebei Medical University Fourth Hospital;   Shanghai Zhongshan Hospital;   Zhejiang Cancer Hospital;   Beijing Hospital;   Liaoning Tumor Hospital & Institute;   Jilin Provincial Tumor Hospital;   Shanxi Province Cancer Hospital;   Tangshan People's Hospital;   China-Japan Union Hospital, Jilin University;   First Hospital of Jilin University;   West China Hospital;   Peking Union Medical College Hospital;   Anyang Tumor Hospital;   Guizhou people's Hospital;   Henan Cancer Hospital;   Wuhan University;   Beijing Cancer Hospital;   Fudan University;   TAIZHOU HOSPITAL OF ZHEJIANG PROVINCE;   Fourth Military Medical University;   Shanxi Dayi Hospital;   First Affiliated Hospital Xi'an Jiaotong University;   Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University;   Fuwai Hospital of Chinese Academy of Medical Sciences
Recruiting

Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection

Conditions:   Coronary Aneurysm;   Dermatitis, Atopic;   Immune System Diseases;   STAT3 Transcription Factor;   Job Syndrome
Intervention:  
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Albert Einstein College of Medicine
Recruiting

The Safety and Efficacy of Istaroxime for Pre-Cardiogenic Shock

Condition:   Cardiogenic Shock
Interventions:   Drug: Istaroxime;   Drug: Placebo
Sponsors:   Windtree Therapeutics;   Momentum Research, Inc.
Not yet recruiting

A Randomized Non-inferiority Study of Low-dose and Standard-dose Ticagrelor After Intervention for Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Coronary Stent Implantation
Interventions:   Drug: Ticagrelor 60mg;   Drug: Ticagrelor 90mg
Sponsors:   Shanghai Tong Ren Hospital;   Shanghai Jiao Tong University School of Medicine;   Fudan University
Recruiting

Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock.

Condition:   Cardiogenic Shock
Interventions:   Combination Product: Hydrocortisone + Flucortac;   Other: Placebo
Sponsor:   CMC Ambroise Paré
Recruiting

Pre-hospital ECG in Acute Coronary Syndromes

Conditions:   Acute Coronary Syndrome;   STEMI;   Non STEMI
Intervention:   Other: No interventions
Sponsors:   Kingston University;   Swansea University;   University of Leeds;   London Ambulance Service;   West Midlands Ambulance Service NHS Foundation Trust;   South West Ambulance Service NHS Foundation Trust
Completed

Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Biological: Apolipoprotein A-I [human] (apoA-I);   Other: Placebo
Sponsor:   CSL Behring
Active, not recruiting

Inova Cardiogenic Shock Registry (INOVA SHOCK)

Condition:   Cardiogenic Shock
Intervention:   Procedure: Cardiogenic Shock team activation
Sponsor:   Inova Health Care Services
Recruiting

Prospective Registry of Acute Coronary Syndromes in Ferrara

Condition:   Acute Coronary Syndromes
Intervention:   Other: prospective collection of data and follow-up
Sponsor:   University Hospital of Ferrara
Recruiting

Cardiovascular Complications and COVID-19 (CovCardioVasc)

Conditions:   COVID;   Acute Coronary Syndrome;   Myocardial Infarction;   Myocarditis;   Venous Thromboembolism;   Deep Vein Thrombosis;   Pulmonary Embolism
Intervention:  
Sponsor:   Centre Hospitalier Universitaire de Nice
Recruiting

High-Sensitivity Cardiac Troponin T to OPtimize Chest Pain Risk Stratification

Conditions:   Acute Coronary Syndrome;   Chest Pain
Interventions:   Procedure: Blood Sample;   Behavioral: HEART Score
Sponsors:   University of Florida;   Roche Diagnostics
Active, not recruiting

Randomized Trial of COBRA PzF Stenting to Reduce Duration of Triple Therapy

Conditions:   Angina, Stable;   Angina, Unstable;   Anticoagulants
Interventions:   Device: COBRA PzF;   Device: Drug Eluting Stent
Sponsor:   CeloNova BioSciences, Inc.
Recruiting

Prognosis of Patients With Acute Coronary Syndrome Complicated With Renal Insufficiency(PACS-RI)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Henan Institute of Cardiovascular Epidemiology
Completed

Early Diagnosis of Acute Myocardial Infarction: Impact of an Educational and Organizational Intervention

Conditions:   STEMI;   Myocardial Infarction;   Nurses;   Education;   Emergency Room
Interventions:   Other: Educational and organizational intervention;   Other: Common Practice
Sponsor:   Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Recruiting

Post-Surgery Extracorporeal Life Support

Conditions:   Cardiogenic Shock;   Extracorporeal Life Support;   Extracorporeal Membrane Oxygenation Complication;   Post Cardiac Arrest Syndrome;   Post-cardiac Surgery
Intervention:   Procedure: ECLS
Sponsors:   University of Florence;   Sandro Gelsomino;   Edvin Prifti;   Francesco Cabrucci;   Marco Bugetti;   Orlando Parise;   Aleksander Dokollari
Recruiting

Fast Radial Pharmaco-invasive Strategy In ST Elevation Myocardial Infarction Trial

Condition:   ST-segment Elevation Myocardial Infarction (STEMI)
Interventions:   Procedure: Cardiac catheterization standard strategy;   Procedure: Cardiac catheterization fast strategy
Sponsor:   University of Sao Paulo General Hospital
Recruiting

HELicobacter Pylori Screening in Patients With Acute Myocardial Infarction Pilot Study

Conditions:   STEMI - ST Elevation Myocardial Infarction;   NSTEMI - Non-ST Segment Elevation MI
Intervention:   Diagnostic Test: Helicobacter Pylori screening by UBT
Sponsor:   Karolinska Institutet
Recruiting

SP16 Inflammatory Response Inhibition Trial

Conditions:   Myocardial Infarction;   Inflammation
Intervention:   Drug: SP16
Sponsors:   Virginia Commonwealth University;   Serpin Pharma, LLC
Active, not recruiting

SONOthrombolysis in Patients With an ST-segment Elevation Myocardial Infarction With fibrinoLYSIS (SONOSTEMI-LYSIS) Trial

Condition:   ST Elevation Myocardial Infarction
Intervention:   Drug: Definity® with High Mechanical Index Ultrasound
Sponsors:   University of Alberta;   Canadian VIGOUR Centre
Not yet recruiting

Physical Activity Intervention in ELderly Patients With Myocardial INfarction

Conditions:   Myocardial Infarction;   Aging
Interventions:   Other: Health Education;   Other: Exercise Intervention
Sponsors:   University Hospital of Ferrara;   Azienda Usl di Bologna
Recruiting

Implementing Precision Medicine Approaches to Guide Anti-platelet Selection

Conditions:   Acute Coronary Syndrome (ACS);   STEMI - ST Elevation Myocardial Infarction (MI);   NSTEMI - Non-ST Segment Elevation MI;   Unstable Angina (UA)
Intervention:   Genetic: CYP2C19 genotyping
Sponsor:   University of Southern California
Active, not recruiting

Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI-DTU Trial

Condition:   ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Intervention:   Device: Impella CP® placement prior to reperfusion with Primary PCI
Sponsor:   Abiomed Inc.
Recruiting

Facilitating Catheter Guidance to Optimal Site for VT Ablation

Condition:   Post-myocardial Infarction Ventricular Tachycardia
Intervention:   Procedure: Radiofrequency catheter ablation
Sponsors:   University of Exeter;   Medical Research Council;   EPSRC;   University Hospitals Bristol NHS Foundation Trust
Not yet recruiting

Paroxetine-mediated GRK2 Inhibition to Reduce Cardiac Remodeling After Acute Myocardial Infarction

Conditions:   Cardiac Remodeling;   Myocardial Infarction
Interventions:   Drug: Paroxetine;   Drug: Placebo oral capsule
Sponsor:   University Hospital Inselspital, Berne
Recruiting

Effects of Morphine on Loading-dose Ticagrelor in Patients With ST-segment Elevation Myocardial Infarction

Condition:   ST-segment Elevation Myocardial Infarction
Interventions:   Drug: Morphine;   Drug: metoclopramide;   Drug: saline
Sponsor:   General Hospital of Chinese Armed Police Forces
Recruiting

Intervention in Frailty Versus Usual Care in Frail Patients After an Acute Myocardial Infarction

Condition:   Fragility
Intervention:   Other: Intervention on frailty
Sponsor:   University of Valencia
Completed

High-Intensity Interval Training Early After Left Ventricular Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Other: HIIT;   Other: MICE
Sponsor:   University Hospital Inselspital, Berne
Active, not recruiting

Cardiogenic Shock Integrated PHenotyping for Event Reduction

Condition:   Heart Failure
Intervention:   Diagnostic Test: ELISA
Sponsor:   Niguarda Hospital
Recruiting

DPP-4 Inhibitors and Acute Myocardial Infarction:Effects on Platelet Function

Condition:   Platelet Aggregation During Acute Myocardial Infarction
Interventions:   Drug: sitagliptin OR saxagliptin;   Drug: placebo
Sponsors:   University of Sao Paulo General Hospital;   InCor Heart Institute
Recruiting

Biomarkers in Acute Cardiac Care

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction;   Chest Pain
Intervention:  
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Recruiting

TicAgrelor Versus CLOpidogrel in Stabilized Patients With Acute Myocardial Infarction: TALOS-AMI

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Aspirin+Ticagrelor;   Drug: Aspirin+Clopidogrel
Sponsors:   The Catholic University of Korea;   Chonnam National University Hospital
Completed

Imaging Silent Brain Infarct And Thrombosis in Acute Myocardial Infarction

Conditions:   Myocardial Infarction;   Acute Disease;   Thrombosis;   Heart Diseases;   Stroke
Interventions:   Other: Doppler echocardiogram exam;   Other: Carotid duplex ultrasound exam;   Other: Cardiac MRI;   Other: Brain MRI;   Procedure: Reveal LINQ insertable cardiac monitoring system;   Other: Coagulation blood test;   Other: Transcranial Doppler monitoring
Sponsor:   Hospital General Universitario Gregorio Marañon
Recruiting

Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention

Condition:   Acute ST Segment Elevation Myocardial Infarction
Interventions:   Drug: NAC;   Drug: Saline
Sponsor:   Suleyman Demirel University
Active, not recruiting

Optimal Antithrombotic Therapy for ACS Patients Concomitant AF Undergoing New Generation DES Implantation

Conditions:   Acute Coronary Syndrome (ACS);   Non-valvular Atrial Fibrillation (NVAF)
Interventions:   Drug: Triple antithrombotic therapy;   Drug: Dual antithrombotc therapy
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting

Association of Long-term Conditions With Survival Following Heart Attack in England and Wales

Conditions:   Acute Myocardial Infarction;   Diabetes Mellitus;   Peripheral Vascular Disease;   Chronic Heart Failure;   Cerebrovascular Disease;   Chronic Renal Failure;   Chronic Obstructive Pulmonary Disease
Intervention:   Other: long term conditions
Sponsor:   Marlous Hall
Active, not recruiting

Prochymal® (Human Adult Stem Cells) Intravenous Infusion Following Acute Myocardial Infarction (AMI)

Condition:   Myocardial Infarction
Interventions:   Drug: Prochymal®;   Drug: Placebo
Sponsor:   Mesoblast, Inc.
Completed

Acute Coronary Syndrome and Care-Seeking Delay: A Web Based Behavioral Study

Conditions:   Acute Myocardial Infarction;   Heart Attack;   Acute Coronary Syndrome;   Unstable Angina
Intervention:  
Sponsors:   Yale University;   Ohio State University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Examining Heart Attacks in Young Women

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsors:   Yale University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Omega-3 Fatty Acids in Elderly Patients With Acute Myocardial Infarction

Conditions:   Myocardial Infarction;   Heart Failure;   Myocardial Revascularization;   Atrial Fibrillation
Interventions:   Drug: Pikasol;   Other: Corn oil
Sponsors:   Oslo University Hospital;   University Hospital, Akershus;   Asker & Baerum Hospital;   Helse Stavanger HF
Active, not recruiting

European Prevention of Alzheimer's Dementia (EPAD) Longitudinal Cohort Study (LCS)

Condition:   Alzheimer's Dementia
Intervention:  
Sponsors:   University of Edinburgh;   Innovative Medicines Initiative
Terminated