Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Mobile Health Strategies for Veterans

Condition:   Coronary Heart Disease
Interventions:   Behavioral: Text Message;   Behavioral: Mobile Application;   Other: Website
Sponsors:   University of California, San Francisco;   San Francisco Veterans Affairs Medical Center
Recruiting - verified January 2017

"Radial Ultra Support Technique" (RUS Technique)

Conditions:   Coronary Arterioscleroses;   Coronary Artery Disease
Interventions:   Procedure: RUS technique;   Procedure: Anchoring Technique;   Procedure: Coronary stenting
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Completed - verified January 2017

Syndrome Differentiation in the Management of Chronic Stable Coronary Artery Disease (SCAD) to Improve Quality

Condition:   Chronic Stable Coronary Artery Disease
Intervention:   Drug: Chinese Herb
Sponsor:   First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Recruiting - verified January 2017

Comparisons of Morphological Measurement Between Coronary Computed Tomography and Optical Coherence Tomography

Condition:   Coronary Artery Disease
Intervention:   Other: data collection, non-intervention
Sponsors:   Kobe University;   HeartFlow, Inc.
Completed - verified January 2017

Coronary Artery Healing and Bioresorbable Scaffold

Conditions:   Myocardial Infarction;   Coronary Artery Disease
Interventions:   Device: OCT guided PCI;   Device: Angiography guided PCI
Sponsor:   Odense University Hospital
Not yet recruiting - verified January 2017

Women's Heart Attack Research Program: Platelet Sub-Study (HARP)

Condition:   Myocardial Infarction
Intervention:  
Sponsor:   New York University School of Medicine
Recruiting - verified January 2017

Physical Activity Intervention for Patients With Reduced Physical Performance After Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Exercise-Related Amenorrhea
Interventions:   Other: physical activity intervention;   Other: standard of care
Sponsor:   University Hospital of Ferrara
Recruiting - verified January 2017

Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen

Conditions:   High Bleeding Risk;   Coronary Artery Disease;   PCI
Interventions:   Drug: Aspirin;   Drug: P2Y12 inhibitor;   Drug: Clopidogrel
Sponsors:   ECRI bv;   Cardialysis B.V.;   European Cardiovascular Research Center;   University of Bern;   Terumo Medical Corporation
Not yet recruiting - verified January 2017

Cohort Description of Younger With AV-block

Conditions:   Atrioventricular Block;   Progressive Cardiac Conduction Defect;   Genetic Disease
Intervention:   Device: Pacemaker
Sponsor:   University of Aarhus
Not yet recruiting - verified January 2017

Coronary Artery Plaque Burden and Morphology in Type 2 Diabetes Mellitus.

Conditions:   Type2 Diabetes;   Atherosclerosis;   Plaque, Atherosclerotic;   Plaque Vulnerability;   Diabetes Complications;   Microalbuminuria;   Coronary Computed Tomography Angiography
Intervention:  
Sponsor:   Svendborg Hospital
Recruiting - verified January 2017

Chewing Ticagrelor Versus Prasugrel in ST-elevation Myocardial Infarction - A Platelet Reactivity Study

Conditions:   Acute Coronary Syndrome;   STEMI
Interventions:   Drug: Chewing Ticagrelor LD;   Drug: Chewing Prasugrel LD
Sponsor:   Sheba Medical Center
Not yet recruiting - verified January 2017

A Behavioral Economics-Based Telehealth Intervention to Improve Post-MI Medication Adherence

Conditions:   Myocardial Infarction, Acute;   Myocardial Infarction
Intervention:   Behavioral: Financial Incentive and Mobile Phone App
Sponsors:   Wellth Inc.;   University of Pennsylvania
Not yet recruiting - verified January 2017

Arrhythmia Genetics in the NEtherlandS

Conditions:   Myocardial Infarction First;   Ventricular Fibrillation
Intervention:  
Sponsor:   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Enrolling by invitation - verified January 2017

Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017

Conditions:   Coronary Artery Disease;   Cardiac Disease;   Malignancy, Second
Intervention:  
Sponsor:   Klinikum der Universitaet Muenchen
Enrolling by invitation - verified January 2017

Brain, Cardiac Hemodynamics and Cognition During Exercise in Subjects With Various Cardiovascular Profiles

Conditions:   Metabolic Syndrome;   Coronary Artery Disease;   Heart Failure
Intervention:   Other: Exercise and Cognitive testing
Sponsor:   Montreal Heart Institute
Active, not recruiting - verified January 2017

Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging

Condition:   Coronary Artery Disease (CAD)
Interventions:   Procedure: Optical Coherence Tomography (OCT);   Procedure: Intravascular Ultrasound (IVUS)
Sponsor:   Columbia University
Recruiting - verified January 2017

Acute and Chronic Protective Effects of Peri-interventional Administration of Levosimendan in ST Elevation Myocardial Infarctions

Conditions:   Myocardial Infarction;   Outcome
Intervention:   Drug: Levosimendan
Sponsor:   RWTH Aachen University
Not yet recruiting - verified January 2017

Therapeutic Effect of Local Hypothermia in Treatment of Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:   Procedure: Infusion of Cold Saline into Local Infarction Myocardium.
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Not yet recruiting - verified December 2016

Comparison of Orbital Versus Rotational Atherectomy Effects On Coronary Microcirculation in PCI

Condition:   Coronary Artery Disease (CAD)
Interventions:   Device: Orbital Atherectomy System (OAS);   Device: Rotablator Rotational Atherectomy System;   Procedure: Magnetic Resonance Imaging (MRI)
Sponsor:   Columbia University
Not yet recruiting - verified January 2017

Biomarker Effectiveness Analysis in Contrast Nephropathy (BEACON)

Conditions:   Acute Renal Failure;   Kidney Diseases;   Chronic Kidney Disease;   Coronary (Artery); Disease
Intervention:  
Sponsors:   University of Pittsburgh;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   U.S. Department of Veterans Affairs
Active, not recruiting - verified January 2017

Post-Myocardial Infarction Patients in Santa Catarina, Brazil - Catarina Heart Study

Condition:   Myocardial Infarction
Intervention:   Other: Myocardial Infarction
Sponsor:   Instituto de Cardiologia de Santa Catarina
Enrolling by invitation - verified January 2017

Safety and Tolerability of Sodium Thiosulfate in Patients With an ACS Undergoing PCI Via Radial Approach.

Condition:   Acute Coronary Syndrome
Intervention:   Drug: Sodium Thiosulfate Pentahydrate
Sponsor:   University Medical Center Groningen
Not yet recruiting - verified January 2017

The Use of the Master Caution System (MCS) for Continuous Monitoring and Detection of Dysrhythmias and Ischemic Events

Condition:   Acute Coronary Syndrome
Intervention:   Device: Master Caution System
Sponsor:   HealthWatch Ltd.
Recruiting - verified December 2016

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY 1142524 in Patients After Acute Myocardial Infarction With Left-ventricular Dysfunction

Condition:   Myocardial Infarction
Interventions:   Drug: BAY1142524;   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified January 2017

Treating Heart Failure With Enhanced External Counterpulsation (EECP)

Condition:   Heart Failure
Intervention:  
Sponsor:   Charite University, Berlin, Germany
Recruiting - verified January 2017

FLOW Evaluation to Guide Revascularization in Multi-vessel ST-elevation Myocardial Infarction

Conditions:   Acute ST Segment Elevation Myocardial Infarction;   Acute Myocardial Infarction;   Multi Vessel Coronary Artery Disease
Interventions:   Procedure: Angiography guided PCI;   Device: Fractional Flow Reserve (FFR)
Sponsors:   Assistance Publique - Hôpitaux de Paris;   St. Jude Medical;   Ministry of Health, France
Recruiting - verified December 2016

Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI

Condition:   Acute Myocardial Infarction
Interventions:   Drug: LCZ696 (sacubitril/valsartan);   Drug: Ramipril;   Drug: Placebo of LCZ696;   Drug: Placebo of ramipril;   Drug: Valsartan;   Drug: Placebo of valsartan
Sponsor:   Novartis Pharmaceuticals
Recruiting - verified January 2017

The SORT OUT IX STEMI OCT Trial

Condition:   Acute Myocardial Infarction
Interventions:   Device: BioFreedom;   Device: Orsiro
Sponsors:   Odense University Hospital;   Aarhus University Hospital;   Rigshospitalet, Denmark
Recruiting - verified January 2017

Effects of High-intensity Inspiratory Muscle Training in Patients Undergoing Coronary Artery Bypass Grafting Surgery

Condition:   Complications Due to Coronary Artery Bypass Graft
Intervention:   Device: High-intensity IMT + combined exercise
Sponsor:   Universidade Federal de Santa Maria
Recruiting - verified January 2017

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment - at the Time of Coronary Angiography - Affect Management Strategy, Hospital Costs and Outcomes?

Conditions:   Chest Pain;   Stable Angina;   Acute Coronary Syndrome;   Non ST Segment Elevation Acute Coronary Syndrome
Intervention:   Device: Routine Measurement of FFR
Sponsors:   University Hospital Southampton NHS Foundation Trust;   Liverpool Heart and Chest Hospital NHS Foundation Trust
Recruiting - verified January 2017

Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention

Conditions:   Radial Artery Spasm;   Angina;   Coronary Artery Disease
Interventions:   Drug: Topical Nitroglycerine;   Drug: Topical Lidocaine
Sponsor:   Aultman Health Foundation
Recruiting - verified January 2017

Long-term Remote Ischemic Preconditioning Improve the Prognosis of Myocardial Infarction Patients With Emergency Reperfusion Therapy

Condition:   Myocardial Infarction, Acute
Intervention:   Other: remote ischemic preconditioning (RIPC)
Sponsor:   Xuanwu Hospital, Beijing
Not yet recruiting - verified July 2016

Long-term Remote Ischemic Preconditioning Improve Long-term Prognosis of Acute Myocardial Infarction Patients Without Emergency Reperfusion Therapy

Condition:   Myocardial Infarction
Intervention:   Other: reported remote ischemic preconditioning (RIPC)
Sponsor:   Xuanwu Hospital, Beijing
Not yet recruiting - verified July 2016

The Application of Multichannel ECG Analytic System in Cardiovascular Diseases

Condition:   Multichannel ECG System
Intervention:  
Sponsor:   National Taiwan University Hospital
Recruiting - verified January 2017

Study on the Effect of Influenza Vaccination After Heart Attack on Future Cardiovascular Prognosis

Conditions:   Myocardial Infarction;   Influenza, Human;   Influenza Vaccines;   Heart Failure;   Stroke
Interventions:   Biological: Influenza vaccine;   Biological: Placebo
Sponsors:   Ole Frobert, MD, PhD;   Swedish Heart Lung Foundation;   Sanofi Pasteur, a Sanofi Company;   Uppsala University;   Lytics
Recruiting - verified January 2017

Intra-patient Study With Polymer Free Drug Eluting Stent Versus Abluminal Biodegradable Polymer Drug Eluting Stent With Early OCT (Optical Coherence Tomography) Follow up

Condition:   Coronary Artery Disease
Interventions:   Device: Coroflex® ISAR Drug-eluting stent;   Device: Ultimaster® Drug-eluting stent
Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   B.Braun Surgical SA
Recruiting - verified January 2017

Analysis Between Coronary Angiotomography and High-sensitive Troponin in Intermediate Risk of Acute Coronary Syndrome

Conditions:   Chest Pain;   Acute Coronary Syndrome
Intervention:   Other: troponin measurement
Sponsor:   University of Sao Paulo General Hospital
Recruiting - verified January 2017

CT COMPARE: CT COronary Angiography to Measure PlAque REduction

Condition:   Cardiovascular Disease
Interventions:   Drug: Rosuvastatin;   Drug: Atorvastatin
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified November 2016

Registry Of Acute meDical Emergencies in Brazil

Conditions:   Acute Coronary Syndromes;   Heart Failure;   Pulmonary Edema;   Aortic Aneurysm, Familial Thoracic 1;   Chest Pain;   Pulmonary Embolism;   Syncope
Intervention:   Other: no intervention
Sponsor:   University of Sao Paulo General Hospital
Recruiting - verified January 2017

Prebiotic in Preventing Low Birth Weight

Conditions:   Birth Weight <2500gm;   Genitourinary Tract Infection
Interventions:   Dietary Supplement: Fructooligosaccharide;   Dietary Supplement: Pocari-Sweat
Sponsors:   International Centre for Diarrhoeal Disease Research, Bangladesh;   Karolinska Institutet;   Swedish International Development Cooperation Agency (SIDA)
Recruiting - verified December 2016

Chewing Versus Traditional Oral Administration of Ticagrelor in STEMI Patients

Conditions:   Acute Coronary Syndromes;   ST Elevation Myocardial Infarction
Interventions:   Drug: Chewing Ticagrelor;   Drug: Oral Ticagrelor
Sponsor:   Sheba Medical Center
Completed - verified January 2017

PARA-HEART Pilot Implementation

Conditions:   Acute Coronary Syndrome;   Chest Pain
Intervention:  
Sponsor:   Wake Forest University Health Sciences
Recruiting - verified January 2017

French Observatory on the Management of Cardiogenic Shock in 2016

Condition:   Shock, Cardiogenic
Intervention:  
Sponsor:   French Cardiology Society
Active, not recruiting - verified January 2017

A Randomized, Pharmacodynamic Comparison of Low Dose Ticagrelor to Clopidogrel in Patients With Prior Myocardial Infarction

Conditions:   Myocardial Infarction;   Diabetes Mellitus;   Renal Disease;   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsors:   University of Patras;   AstraZeneca
Recruiting - verified January 2017

Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics, of MEDI6012 in Subjects With Stable Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Biological: MEDI6012;   Biological: Placebo
Sponsor:   MedImmune LLC
Completed - verified January 2017

Clinical Performance Evaluation of AQT90 FLEX TnI and TnT

Condition:   Myocardial Infarction
Intervention:  
Sponsor:   Radiometer Medical ApS
Recruiting - verified January 2017

Peer Mentored Approaches for Women With Coronary Artery Disease ("4-Steps")

Condition:   Coronary Artery Disease
Interventions:   Behavioral: Peer Mentor;   Behavioral: Transcendental Meditation
Sponsor:   Weill Medical College of Cornell University
Recruiting - verified January 2017

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified January 2017

Exercise Capacity in Diseases and Health

Condition:   Exercise Capacity
Intervention:  
Sponsor:   Rambam Health Care Campus
Not yet recruiting - verified January 2017

The Angioshield Study Feasibility II

Condition:   Coronary Artery Disease
Intervention:   Device: Angioshield
Sponsor:   Neograft Technologies, Incorporated
Recruiting - verified January 2017

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

Conditions:   Secondary Prevention;   Stroke;   Ischemic Heart Disease;   Coronary Heart Disease
Interventions:   Drug: Acetylsalicylic Acid (Asprin, BAYE4465);   Drug: Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
Sponsor:   Bayer
Recruiting - verified January 2017

The Evaluation and Management of Patients With Acute Chest Pain in China

Conditions:   Acute Chest Pain;   Acute Coronary Syndrome
Intervention:  
Sponsors:   Yuguo Chen;   People's Hospital of Jinxiang County;   People's Hospital of Chengwu;   Traditional Chinese Medicine Hospital of Wucheng County;   People's Hospital of Longkou City;   People's Hospital of Gaomi City;   Linyi People's Hospital;   People's Hospital of Wenshang County;   The 2nd People's Hospital of Liaocheng City;   People's Hospital of Shouguang City;   Traditional Chinese Medicine Hospital of Pingyin County;   Traditional Chinese Medicine Hospital of Laoling City;   The 2nd People's Hospital of Dongying City;   Affiliated Hospital of Shandong Academy of Medical Sciences;   People's Hospital of Shizhong District, Jinan City;   The 2nd People's Hospital of Dezhou City;   Central Hospital of Zibo City;   Jining Medical University;   People's Hospital of Mudan, Heze City;   The 3rd People's Hospital of Jinan City;   Qianfoshan Hospital;   Xinlongzhuang Colliery Hospital;   The 2nd Traditional Chinese Medicine Hospital of Taian City;   Qilu Hospital
Recruiting - verified January 2017

Exercise and Pharmacotherapy for Anxiety in Cardiac Patients

Conditions:   Anxiety;   Cardiovascular Disease
Interventions:   Drug: Lexapro;   Drug: Placebo;   Behavioral: Supervised Aerboic Exercise
Sponsor:   Duke University
Recruiting - verified January 2017

Serum Irisin in Myocardial Infraction and Following Percutaneous Coronary Intevention

Conditions:   Myocardial Infarction;   Coronary Artery Disease
Interventions:   Procedure: percutaneous coronary intervention;   Procedure: coronary angiography;   Device: Stent, Medronic Resolute Integrity
Sponsor:   424 General Military Hospital
Completed - verified January 2017

Aspirin Twice a Day in Patients With Diabetes and Acute Coronary Syndrome

Conditions:   Diabetes Mellitus;   Acute Coronary Syndrome;   Coronary Artery Disease
Interventions:   Drug: Novel strategy Aspirin;   Drug: Conventional strategy Aspirin
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Bayer
Recruiting - verified January 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified January 2017

Pericardial Fat and Inflammation in HIV Patients and Controls

Conditions:   Coronary Artery Disease;   Human Immunodeficiency Virus (HIV)
Intervention:  
Sponsor:   University of Cincinnati
Recruiting - verified January 2017

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study

Condition:   Cost Sharing, Acute Coronary Syndrome
Intervention:   Other: Study voucher card
Sponsors:   AstraZeneca;   Duke Clinical Research Institute
Active, not recruiting - verified January 2017

Frailty in Elderly Patients Receiving Cardiac Interventional Procedures

Condition:   Aged
Intervention:   Other: frailty evaluation
Sponsor:   University Hospital of Ferrara
Active, not recruiting - verified January 2017

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Harvard Clinical Research Institute;   Medstar Health Research Institute
Active, not recruiting - verified January 2017

Brilinta Taiwan Post Approval Safety Study

Condition:   Non ST-elevation Myocardial Infarction
Intervention:   Drug: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Sponsor:   AstraZeneca
Active, not recruiting - verified January 2017

Antithrombotic Strategy Variability In ATrial Fibrillation and Obstructive Coronary Disease Revascularized With PCI - The AVIATOR 2 Registry

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Icahn School of Medicine at Mount Sinai;   Bristol-Myers Squibb
Recruiting - verified January 2017

Differential Effect of High (200μg/kg/Min) Adenosine Dose on Fractional Flow Reserve in Patients Presenting Variation of FFR ≥0.05 During the Usual Dose of Adenosine Infusion (140μg/kg/Min).

Condition:   Coronary Artery Disease
Intervention:   Drug: Adenosine infusion at 200μg/Kg/min
Sponsor:   University of Patras
Completed - verified January 2017

Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Colchimax®;   Drug: Conventional treatment
Sponsor:   University Hospital, Montpellier
Completed - verified January 2017

Two-stent vs Provisional Stenting Techniques for Patients With Complex Coronary Bifurcation Lesions

Condition:   Coronary Artery Disease
Interventions:   Procedure: Two-stenting technique;   Procedure: Simple stenting technique;   Procedure: Percutaneous Coronary Intervention
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified January 2017

Effects of Pitavastatin on Insulin Sensitivity and Liver Fat

Conditions:   Obesity;   Fatty Liver, Nonalcoholic
Interventions:   Drug: pitavastatin;   Other: PLACEBO
Sponsor:   Massachusetts General Hospital
Recruiting - verified January 2017

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified January 2017

Laparoscopy-assisted and Open Distal Gastrectomy for Gastric Cancer in the Elderly Patients

Condition:   Complications
Interventions:   Procedure: Laparoscopic gastrectomy;   Procedure: Open gastrectomy
Sponsor:   Nanfang Hospital of Southern Medical University
Recruiting - verified January 2017

Multi-cap for Increase Adherence After Acute Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Other: Combined capsule;   Other: Conventional therapy
Sponsor:   Hospital El Cruce
Terminated - verified January 2017

Intravascular Ultrasound Guided Drug Eluting Stent Implantation in "All-comers" Coronary Lesions

Condition:   Coronary Artery Disease
Interventions:   Procedure: Angiography;   Procedure: IVUS;   Procedure: DES implantation
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified January 2017

Mediators of Atherosclerosis in South Asians Living in America (MASALA) Social Network Study

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 2017

Computed TomogRaphic Evaluation of Atherosclerotic DEtermiNants of Myocardial IsChEmia

Condition:   Myocardial Ischemia
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 2017

Is Efficacy of PLAtelet Aggregation Inhibition by Ticagrelor Mediated P2Y12 Blockade Dependent Upon Endogenous Endothelial Nitric OXide?

Condition:   Acute Coronary Syndome
Interventions:   Other: Blood Test;   Other: EndoPAT - endothelial assessment
Sponsor:   Jennifer Rossington
Completed - verified January 2017

Rubidium Elution System Performance Testing

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Jubilant DraxImage Inc.
Recruiting - verified January 2017

Evaluation of iFR vs FFR in Stable Angina or Acute Coronary Syndrome

Conditions:   Angina Pectoris;   Acute Myocardial Infarction
Interventions:   Device: iFR;   Device: FFR
Sponsor:   Uppsala University
Completed - verified January 2017

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

Conditions:   Coronary Disease;   Coronary Stenosis
Interventions:   Procedure: FFR guided PCI;   Procedure: CABG
Sponsors:   Stanford University;   VZW Cardiovascular Research Center Aalst;   Catharina Ziekenhuis Eindhoven;   Golden Jubilee National Hospital;   University of California, Irvine;   Medtronic;   St. Jude Medical;   Genae;   King's College Hospital, London;   Houston Methodist DeBakey Heart and Vascular Center, Houston
Recruiting - verified January 2017

Angioshield First-In-Human Study to Demonstrate the Preliminary Safety and Efficacy

Condition:   Coronary Artery Disease
Intervention:   Device: Angioshield
Sponsor:   Neograft Technologies, Incorporated
Completed - verified January 2017

Differential Effect of Ticagrelor Versus Prasugrel Maintenance Dose on Endothelial Function of Peripheral Vessels in Patients With Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Endothelial Function
Interventions:   Drug: Ticagrelor;   Drug: Prasugrel
Sponsor:   University of Patras
Completed - verified January 2017

Post Acute Coronary Event Smoking Study

Conditions:   Smoking Cessation;   Acute Coronary Syndrome
Interventions:   Behavioral: Behavioral Activation (BA);   Behavioral: Standard Smoking Cessation Counseling;   Drug: Nicotine patch;   Other: Printed Self-help materials for Smoking Cessation
Sponsor:   The Miriam Hospital
Completed - verified January 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified January 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified January 2017

Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention

Condition:   Acute ST Segment Elevation Myocardial Infarction
Interventions:   Drug: NAC;   Drug: Saline
Sponsor:   Suleyman Demirel University
Active, not recruiting - verified January 2017

Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Interventions:   Drug: N-acetyl cysteine;   Drug: Saline
Sponsor:   Suleyman Demirel University
Active, not recruiting - verified January 2017

Effect of Ticagrelor vs. Dipyridamole on Adenosine Uptake

Condition:   Coronary Artery Disease
Intervention:   Drug: Adenosine
Sponsor:   Vanderbilt University
Completed - verified January 2017

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: Placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified January 2017

Tailored Antiplatelet Therapy Versus Recommended Dose of Prasugrel

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Modification of Prasugrel based on a biological assay;   Drug: prasugrel / clopidogrel;   Device: Verify Now
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Eli Lilly and Company;   Daiichi Sankyo Inc.;   Allies in Cardiovascular Trials Initiatives and Organized;   Accumetrics, Inc.;   Stentys
Completed - verified January 2017

Phase II Clinical Trial to Evaluate the Benefits of Postconditioning in ST-Elevation Myocardial Infarction (STEMI)

Condition:   Acute Myocardial Infarction
Interventions:   Procedure: Post Conditioning + Primary PCI;   Procedure: Standard Primary PCI
Sponsors:   Minneapolis Heart Institute Foundation;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified January 2017

IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)

Conditions:   Heart Failure;   Coronary Artery Disease;   Ischemic Cardiomyopathy;   Non-ischemic Cardiomyopathy
Interventions:   Other: Advanced cardiac imaging;   Other: Standard Cardiac Imaging
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR);   The Finnish Funding Agency for Technology and Innovation (TEKES)
Recruiting - verified January 2017

Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI)

Condition:   Coronary Artery Disease
Intervention:   Other: Myocardial perfusion imaging using Rb-82 PET or Tc-99m or Tl SPECT
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified January 2017

De Novo Pilot Study, Lutonix Catheter in Conjunction With Bare Metal Stenting for Treatment of Coronary De Novo Lesions

Condition:   Coronary Artery Stenosis
Intervention:   Device: Lutonix Paclitaxel-Coated Balloon
Sponsor:   C. R. Bard
Completed - verified January 2017

The SMARTEX Heart Failure Study

Condition:   Heart Failure
Interventions:   Behavioral: high-intensity interval training;   Behavioral: Moderate continuous training;   Behavioral: Recommendation of regular moderate exercise
Sponsors:   Norwegian University of Science and Technology;   University Hospital, Antwerp;   UMC Utrecht;   Technische Universität München;   Heartcenter Leipzig GmbH;   Bispebjerg Hospital;   St. Olavs Hospital;   Helse Stavanger HF;   Scientific Institute of Veruno;   Centre Hospitalier du Luxembourg;   Alesund Hospital;   Levanger Hospital
Completed - verified November 2016

Acarbose Cardiovascular Evaluation Trial

Conditions:   Coronary Heart Disease;   Acute Coronary Syndrome;   Impaired Glucose Tolerance;   Type 2 Diabetes Mellitus (T2DM)
Interventions:   Drug: Acarbose;   Drug: Matching Placebo
Sponsors:   University of Oxford;   Bayer
Active, not recruiting - verified January 2017

Cardiac FDG PET Viability Registry

Conditions:   Heart Failure;   Ischemic Heart Disease;   Myocardial Dysfunction
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Ontario Ministry of Health and Long Term Care
Recruiting - verified January 2017

Effects of Intracoronary Progenitor Cell Therapy on Coronary Flow Reserve After Acute MI

Conditions:   Coronary Artery Disease;   Acute Myocardial Infarction
Interventions:   Biological: autologous bone marrow-derived progenitor cells;   Biological: placebo medium
Sponsors:   Johann Wolfgang Goethe University Hospital;   University of Leipzig
Terminated - verified January 2017

PET and Recovery Following Revascularization (PARR 2)

Conditions:   Coronary Artery Disease;   Ventricular Dysfunction, Left
Interventions:   Procedure: Positron emission tomography: FDG viability imaging;   Other: PET imaging
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR);   Heart and Stroke Foundation of Ontario
Completed - verified January 2017

Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients

Conditions:   Heart Failure;   Coronary Artery Disease
Intervention:   Behavioral: Strength training intervention
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital
Completed - verified November 2011

Multicenter Unsustained Tachycardia Trial (MUSTT)

Conditions:   Arrhythmia;   Cardiovascular Diseases;   Coronary Disease;   Death, Sudden, Cardiac;   Heart Diseases;   Myocardial Ischemia;   Tachycardia, Ventricular
Interventions:   Procedure: electrophysiology;   Drug: anti-arrhythmia agents;   Device: defibrillators, implantable
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 2004