Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Fastigial Nucleus Stimulation for Coronary Heart Disease

Condition:   Coronary Disease
Interventions:   Device: Fastigial Nucleus Stimulation;   Drug: Standard treatment
Sponsors:   Affiliated Hospital of North Sichuan Medical College;   the Third Hospital of Mianyang
Enrolling by invitation

Dynamic Computed Tomography Myocardial Perfusion Imaging for Detection of Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Ischemia
Intervention:   Diagnostic Test: Computed Tomography Angiography
Sponsors:   Johns Hopkins University;   Toshiba Medical Systems Corporation, Japan
Recruiting

Expression of Trefoil Factors and Adrenomedullin in Subjects With Chronic Periodontitis and Coronary Heart Disease

Conditions:   Coronary Heart Disease;   Periodontal Diseases
Intervention:  
Sponsor:   Meenakshi Ammal Dental College and Hospital
Recruiting

Cost-effectiveness and Safety of the CADScorSystem in Patients With Symptoms Suggestive of Stable Coronary Artery Disease.

Condition:   Angina, Stable
Intervention:   Device: CAD-score
Sponsors:   Bispebjerg Hospital;   Region Hovedstaden;   Larix A/S;   Acarix;   Kai Hansens Fond;   Kai Houmann Nielsens Fond
Active, not recruiting

Coronary Steal Via Natural Internal Mammary Artery-To-Coronary Artery Bypasses

Conditions:   Coronary Artery Disease;   Ischemia
Intervention:   Other: Coronary Artery Balloon Occlusion for Determination of Collateral Flow Index
Sponsor:   University Hospital Inselspital, Berne
Recruiting

Early Detection of Myocardial Ischaemia in Suspected Acute Coronary Syndromes by Apo J-Glyc

Condition:   Myocardial Ischemia
Intervention:   Diagnostic Test: Blood collection
Sponsor:   Glycardial Diagnostics S.L.
Recruiting

Study on the Registration of Coronary Heart Disease Patients Undergoing PCI

Condition:   Coronary Heart Disease
Intervention:   Drug: antiplatelet agents(Clopidogrel or Ticagrelor)
Sponsor:   The Third Xiangya Hospital of Central South University
Completed

Computed TomogRaphic Evaluation of Atherosclerotic DEtermiNants of Myocardial IsChEmia

Condition:   Myocardial Ischemia
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Evaluation of M118 in Percutaneous Coronary Intervention (EMINENCE)

Condition:   Coronary Artery Disease (CAD)
Interventions:   Drug: M118;   Drug: Unfractionated Heparin
Sponsor:   Momenta Pharmaceuticals, Inc.
Completed

QUANTIFICATION OF NLRP3 (rs4612666) AND CARD8 GENE (rs20432111) IN CHRONIC PERIODONTITIS SUBJECTS

Conditions:   Periodontal Diseases;   Coronary Artery Disease
Intervention:  
Sponsor:   Meenakshi Ammal Dental College and Hospital
Recruiting

Rehabilitation at Home Using Mobile Health In Older Adults After Hospitalization for Ischemic Heart Disease

Condition:   Ischemic Heart Disease
Interventions:   Other: mHealth-CR;   Other: Usual Care
Sponsors:   NYU Langone Health;   National Institutes of Health (NIH)
Not yet recruiting

GaStroEsophageal effeCt of indobUfen Versus aspiRin in Patients Undergoing Dual antiplatElet Therapy

Conditions:   Coronary Artery Disease;   Gastroesophageal Reflux Disease
Interventions:   Drug: Indobufen and aspirin mimetic;   Drug: Aspirin and indobufen mimetic
Sponsor:   Beijing Anzhen Hospital
Not yet recruiting

Safety Study of Gene Therapy for Ischemic Heart Disease in Korea

Condition:   Ischemic Heart Disease
Intervention:   Biological: VM202RY
Sponsor:   Helixmith Co., Ltd.
Completed

Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis

Condition:   Myocardial Infarction
Intervention:   Other: Stress Challenge
Sponsors:   Emory University;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Prospective International Study of Coronary Subtraction Using 320 Detector Row CT (CorSub)

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

The Study Design of a Mobile Health (mHealth) Technology Associated Improvement of Drug Adherence in Patients With Acute Myocardial Infarction and Protocol for the Randomized, Controlled Trial(RESCIND-3)

Condition:   Coronary Artery Disease
Interventions:   Behavioral: Usual Text Messages;   Behavioral: Personalized reminders;   Behavioral: Internet-based counselling
Sponsors:   Guangdong General Hospital;   Maoming General Hospital;   Dongguan People's Hospital;   First People's Hospital, Shunde China;   Guangzhou Panyu Central Hospital
Recruiting

Comparison of Effects of Oxycodone and Sufentanil on Cardiovascular Stress Induced by Tracheal Intubation in the Patients With Coronary Heart Disease Undergoing Major Noncardiac Surgery

Condition:   Cardiovascular
Interventions:   Drug: Oxycodone 10mg;   Drug: Sufentanil
Sponsor:   Shengjing Hospital
Completed

Safety and Efficacy of DCB Therapy for ISR Under the Guidance of QFR (UNIQUE-DCB-II Study )

Condition:   Coronary Heart Disease
Interventions:   Device: drug coated balloon;   Device: drug eluted stent
Sponsor:   Nanjing First Hospital, Nanjing Medical University
Not yet recruiting

Non-isotope Based Imaging Modalities vs Technetium-99m Single-Photon Emission Computed Tomography(99mTcSPECT)

Condition:   Myocardial Ischemia
Intervention:  
Sponsors:   Montreal Heart Institute;   Canadian Institutes of Health Research (CIHR)
Completed

Gene Therapy for the Treatment of Chronic Stable Angina

Condition:   Myocardial Ischemia
Intervention:   Biological: VM202
Sponsor:   Helixmith Co., Ltd.
Withdrawn

The Cerebral-Coronary Connection (C3) Study

Conditions:   Ischemic Heart Disease;   Microvascular Coronary Artery Disease;   Depression;   Endothelial Dysfunction;   Inflammation
Intervention:   Procedure: Coronary Angiography and Multimodal Coronary Physiology Study (FFR, CFR, HMR)
Sponsors:   Instituto de Salud Carlos III;   Hospital San Carlos, Madrid
Recruiting

Intervention in Lifestyle and Therapeutic Adherence After Coronary Event Based on Web Application

Condition:   Coronary Disease
Intervention:   Device: Mobile application
Sponsor:   Instituto de investigación e innovación biomédica de Cádiz
Not yet recruiting

Long-term Outcome of Deferred Lesion Based on FFR

Condition:   Myocardial Ischemia
Intervention:   Diagnostic Test: fractional flow reserve
Sponsor:   University Hospital of Ferrara
Active, not recruiting

GLOBAL LEADERS Adjudication Sub-Study

Conditions:   Coronary Artery Disease;   Platelet-aggregation Inhibitors
Intervention:  
Sponsors:   University Hospital Inselspital, Berne;   European Cardiovascular Research Center
Active, not recruiting

A Lifestyle Physical Activity Intervention for Older Sedentary Women

Condition:   Coronary Heart Disease
Interventions:   Behavioral: Lifestyle Physical Activity Intervention;   Behavioral: Information / Attention Comparison
Sponsor:   University of Arkansas
Completed

Distal Radial Artery vs. Forearm Radial Artery For Cardiac Catheterization

Conditions:   Coronary Artery Disease;   Angina, Unstable;   Angina, Stable;   Non STEMI;   Non ST Segment Elevation Myocardial Infarction;   Acute Coronary Syndrome;   Atheroscleroses, Coronary;   Atherosclerotic Heart Disease With Ischemic Chest Pain;   Chest Pain;   Myocardial Infarction;   Myocardial Ischemia;   ST-segment Elevation Myocardial Infarction (STEMI)
Interventions:   Procedure: distal radial artery access in coronary angiography and angioplasty;   Procedure: Forearm radial artery access in coronary angiography and angioplasty
Sponsor:   An-Najah National University
Recruiting

Dynamic Coronary Roadmap for Contrast Reduction

Condition:   Coronary Artery Disease
Interventions:   Device: PCI with Dynamic Coronary Roadmap;   Device: PCI without Dynamic Coronary Roadmap
Sponsor:   Philips Healthcare
Recruiting

BIOSOLVE-IV Magmaris Swiss Satellite Registry

Condition:   Coronary Artery Disease
Intervention:   Device: Magmaris Resorbable Magnesium Scaffold (RMS)
Sponsor:   University Hospital, Geneva
Recruiting

FiO2 and Outcomes After OPCAB

Condition:   Coronary Artery Disease
Intervention:   Other: Fraction of inspired oxygen level
Sponsor:   Seoul National University Hospital
Recruiting

A Single Arm Study With Resolute Onyx in ONE-Month DAPT for High-Bleeding Risk Patients Who Are Considered One-Month Clear (Onyx ONE Clear)

Condition:   Coronary Artery Disease
Intervention:   Combination Product: Device: Medtronic Resolute Onyx Zotarolimus-Eluting Coronary Stent System Treatment Followed by one-month DAPT
Sponsor:   Medtronic Vascular
Active, not recruiting

A Randomized Controlled Trial With Resolute Onyx in One Month Dual Antiplatelet Therapy (DAPT) for High-Bleeding Risk Patients

Condition:   Coronary Artery Disease
Interventions:   Device: Medtronic Resolute Onyx Zotarolimus-Eluting Coronary Stent System;   Device: Biosensors BioFreedom BA9 Drug Coated Coronary Stent
Sponsor:   Medtronic Vascular
Active, not recruiting

Ultra Low Dose CT for CACS and AC of SPECT

Condition:   Coronary Artery Disease
Interventions:   Device: Ultra low dose non-contrast enhanced CT;   Device: Standard dose non-contrast enhanced CT
Sponsor:   University of Zurich
Completed

Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (The EXACT Trial)

Conditions:   Coronary Artery Disease;   Ischemia;   Angina Refractory;   Cardiovascular Diseases;   Heart Diseases
Intervention:   Biological: AdVEGFXC1
Sponsor:   XyloCor Therapeutics, Inc.
Not yet recruiting

e-NOBORI Observational Registry of Nobori DES

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Terumo Europe N.V.
Completed

Coroflex ISAR 2000 Extended Registry (ISAR2000 Extended)

Condition:   Coronary Artery Disease (CAD)
Intervention:   Device: stenting with the Coroflex ISAR sirolimus-eluting stent
Sponsors:   B. Braun Melsungen AG;   Charite University, Berlin, Germany
Active, not recruiting

Post Market Surveillance of SeQuent Please Neo With Scoring Balloon

Condition:   Coronary Artery Disease (CAD)
Intervention:   Device: Drug Coated Balloon Angioplasty, Scoring Balloon Dilatation
Sponsors:   B. Braun Melsungen AG;   Klinikum Ernst von Bergmann Augenklinik Laserzentrum
Active, not recruiting

The First-In-Man Pilot Study of Firehawk

Condition:   Coronary Heart Disease
Intervention:   Device: Rapamycin target-eluting Coronary Stent System
Sponsor:   Shanghai MicroPort Medical (Group) Co., Ltd.
Completed

Safety and Efficacy of Delayed Continuous Use of Bivalirudin 4 Hours After ePCI (COBER Study)

Condition:   Coronary Heart Disease
Interventions:   Drug: delayed continuous use of bivalirudin;   Drug: bivalirudin use during ePCI
Sponsor:   Nanjing First Hospital, Nanjing Medical University
Recruiting

Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

Condition:   Sickle Cell Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Absorb IV Randomized Controlled Trial

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: Absorb BVS;   Device: XIENCE
Sponsor:   Abbott Medical Devices
Active, not recruiting

Study to Gain Insights in Treatment Patterns and Outcomes in Patients With Atherosclerosis Prescribed to Xarelto in Combination With Acetylsalicylic Acid

Condition:   Atherosclerosis
Interventions:   Drug: Rivaroxaban (BAY59-7939, Xarelto);   Drug: Acetylsalicylic acid
Sponsors:   Bayer;   Janssen, LP
Recruiting

Randomization of Single vs Multiple Arterial Grafts (ROMA) in Female Patients

Conditions:   Heart Diseases;   Coronary Artery Disease
Interventions:   Procedure: Procedure: Single arterial graft;   Procedure: Procedure: Multiple arterial grafting
Sponsors:   Maastricht University Medical Center;   Oxford University Hospitals NHS Trust;   University of Göttingen;   New York Presbyterian Hospital;   Sunnybrook Health Sciences Centre
Not yet recruiting

Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)

Condition:   Coronary Artery Stenosis
Intervention:  
Sponsor:   Matthias Friedrich
Recruiting

Disrupt CAD III With the Shockwave Coronary IVL System

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:   Device: Lithotripsy
Sponsor:   Shockwave Medical, Inc.
Recruiting

Study of cardiovAscular Contrasted Phenotypes in Patients With FamIliaI hypercholesteRolemia

Condition:   Homozygous Familial Hypercholesterolemia
Intervention:   Genetic: Whole Genome Sequencing
Sponsor:   Nantes University Hospital
Recruiting

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Interventions:   Drug: colchicine;   Drug: colchicine placebo
Sponsor:   Montreal Heart Institute
Completed

Coronary Artery Healing and Bioresorbable Scaffold

Conditions:   Myocardial Infarction;   Coronary Artery Disease
Interventions:   Device: OCT guided PCI;   Device: Angiography guided PCI
Sponsor:   Odense University Hospital
Active, not recruiting

Randomized Comparison of Cangrelor, Tirofiban and Prasugrel in Patients With STEMI Referred for Primary PCI.

Conditions:   Coronary Artery Disease;   STEMI - ST Elevation Myocardial Infarction
Interventions:   Drug: Cangrelor;   Drug: Tirofiban;   Drug: Prasugrel
Sponsor:   University Hospital Inselspital, Berne
Active, not recruiting

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   NYU Langone Health;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University
Active, not recruiting

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Population Health Research Institute;   Janssen Research & Development, LLC
Active, not recruiting

Cadmium-zinc-telluride (CZT) Imaging of Myocardial Blood Flow (MBF) (SPECT MBF)

Condition:   Coronary Heart Disease
Intervention:   Other: single photon emission computed tomography
Sponsors:   Ottawa Heart Institute Research Corporation;   GE Healthcare
Recruiting

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Conditions:   Coronary Artery Disease;   Ischemic Heart Disease;   Non ST Segment Elevation Myocardial Infarction
Interventions:   Device: Orbital Atherectomy;   Device: Balloon
Sponsors:   Cardiovascular Systems Inc;   Cardiovascular Research Foundation, New York
Recruiting

Factors Affect Outcomes in Cardiovascular Surgery

Conditions:   Coronary Artery Disease;   Valvular Diseases;   Vascular Diseases
Intervention:  
Sponsor:   University of California, Davis
Recruiting

Dual Energy CT for Ischemia Determination Compared to "Gold Standard" Non-Invasive and Invasive Techniques

Condition:   Ischemia
Intervention:   Procedure: CT and stress test
Sponsors:   Weill Medical College of Cornell University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

CoROnary SinuS Reducer implantatiOn for ischemiA reDuction

Condition:   Refractory Angina Pectoris
Interventions:   Device: Coronary Sinus Reducer device;   Other: Sham procedure
Sponsor:   University Medical Centre Ljubljana
Recruiting

Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI

Conditions:   Obstructive Sleep Apnea;   Diabetes Mellitus;   Coronary Artery Disease
Intervention:  
Sponsors:   National University, Singapore;   National Heart Centre Singapore
Completed

Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention

Conditions:   Radial Artery Spasm;   Angina;   Coronary Artery Disease
Interventions:   Drug: Topical Nitroglycerine;   Drug: Topical Lidocaine
Sponsor:   Aultman Health Foundation
Completed

Safety and Efficacy Study of Gene Therapy for Acute Myocardial Infarction in Korea

Conditions:   Ischemic Heart Disease;   Acute Myocardial Infarction
Interventions:   Biological: Stage 1-Low dose VM202RY;   Biological: Stage 1-Middle dose VM202RY;   Biological: Stage 1-High dose VM202RY;   Drug: Stage 2-Placebo;   Biological: Stage 2-Low dose VM202RY;   Biological: Stage 2-High dose VM202RY;   Device: C-Cathez® Catheter
Sponsor:   Helixmith Co., Ltd.
Withdrawn

The Randomized OPTIMAL-ACT Trial

Conditions:   Coronary Artery Disease;   Ischemic Heart Disease;   Anticoagulant-induced Bleeding;   Coronary Syndrome
Intervention:   Drug: Unfractionated heparin
Sponsor:   Mayo Clinic
Recruiting

Assessment of the Efficacy and Tolerability of the Fixed-dose Combination of Bisoprolol/Perindopril in Patients With Arterial Hypertension and Stable CAD in Daily Clinical Practice

Conditions:   Arterial Hypertension;   CHD - Coronary Heart Disease
Intervention:   Drug: bisoprolol/perindopril FDC
Sponsor:   Servier Russia
Recruiting

Genomic Outcomes of Metformin

Conditions:   Coronary Artery Disease;   Mild Cognitive Impairment;   Obesity, Abdominal;   Hypertension
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsors:   Wake Forest University Health Sciences;   National Institute on Aging (NIA)
Completed

Mindful Hearts Study: Mindfulness to Reduce Stress

Conditions:   Cardiovascular Disease;   Psychological Stress;   Stroke;   Coronary Artery Disease
Interventions:   Behavioral: Mindfulness Based Stress Reduction;   Behavioral: Health Education Program
Sponsor:   VA Office of Research and Development
Completed

Myocardial Infarction, COmbined-device, Recovery Enhancement Study

Conditions:   Acute Myocardial Infarction;   Coronary Artery Disease;   Acute Coronary Syndrome;   Myocardial Infarction
Intervention:   Device: Corrie Digital Health platform
Sponsors:   Johns Hopkins University;   Apple Inc.;   iHealth
Active, not recruiting

Insulin Resistance and Atherosclerosis in Women With Lupus

Conditions:   Systemic Lupus Erythematosus;   Insulin Resistance;   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed

Observational Study of Cardiovascular Disease.

Conditions:   Cardiovascular Diseases;   Cardiovascular Morbidity;   Coronary Heart Disease;   Low-density-lipoprotein-type
Intervention:   Other: N/A - observational study.
Sponsors:   University of Sydney;   The Thrombolysis in Myocardial Infarction Study Group, Harvard University;   Imperial College London;   University of Oslo;   Amgen
Not yet recruiting

Undiagnosed Sleep Apnea and Bypass OperaTion

Condition:   Sleep Apnea
Intervention:  
Sponsor:   National University, Singapore
Active, not recruiting

Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study)

Conditions:   Atherosclerosis;   Cardiovascular Disease;   Vascular Diseases
Intervention:  
Sponsor:   National Institute on Aging (NIA)
Terminated

A Genome-Wide Scan For Quantitative Trait Loci of Serum Bilirubin - A Framingham Study

Condition:   Genetics
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Genetic Factors in Atherosclerosis

Condition:   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed

Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection

Conditions:   Osteopenia;   Scoliosis;   Airway Disease;   Eczema;   Aneurysmal Coronary Artery Disease
Intervention:  
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Albert Einstein College of Medicine
Recruiting

Selected Disorders and Sleep Bruxism

Conditions:   Sleep Bruxism;   Hypertension;   Thyroid Dysfunction;   Mental Status Change;   Sleep Apnea;   Sleep Disorders;   Cardiovascular Risk Factor;   Cardiovascular Diseases;   Temporomandibular Disorder
Intervention:   Drug: Buspirone
Sponsor:   Wroclaw Medical University
Enrolling by invitation

The Health Access and Recovery Peer Program

Conditions:   Hypertension;   Arthritis;   Coronary Artery Disease;   Hepatitis;   Diabetes;   Asthma;   Hyperlipidemia;   HIV
Intervention:   Behavioral: HARP Intervention
Sponsors:   Emory University;   National Institute of Mental Health (NIMH)
Completed

Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up

Conditions:   Diabetes Mellitus;   Hypertension;   Ischemic Heart Disease;   Stroke
Intervention:  
Sponsor:   Oslo University Hospital
Completed

Inferior Vena Cava Diameter Dependent Colloid Challenge Versus Routine Crystalloid Strategy Transurethral Resection Prostate

Condition:   Volume Overload
Intervention:   Other: Ultrasound-guided Inferior vena cava diameter dependent colloid challenge versus routine crystalloid strategy Fluid replacement
Sponsor:   Mansoura University
Not yet recruiting

XIENCE 28 USA Study

Conditions:   Bleeding Disorder;   Ischemic Stroke;   Hemorrhagic Stroke;   Hematological Diseases;   Thrombocytopenia;   Coagulation Disorder;   Anemia;   Renal Insufficiency;   Coronary Artery Disease
Interventions:   Device: XIENCE;   Drug: DAPT (aspirin and/or P2Y12 receptor inhibitor)
Sponsor:   Abbott Medical Devices
Recruiting

Safety and Efficacy of Low Temperature Contrast in UAP Patients During PCI

Condition:   Unstable Angina Pectoris
Intervention:   Other: low temperature contrast
Sponsor:   Nanjing First Hospital, Nanjing Medical University
Recruiting

The Impact of Anxiety, Stress and Pain in the Early Phase of Myocardial Infarction on the Development of Anxiety Symptoms and Posttraumatic Stress Disorder in the Long Term Outcome

Condition:   Myocardial Infarction
Intervention:   Other: No intervention
Sponsor:   Medical University of Graz
Not yet recruiting

Risk Assessment by Cardiovascular Biomarkers in Chronic Dialysis Patients

Condition:   Endstage Renal Disease
Intervention:  
Sponsor:   University Hospital, Basel, Switzerland
Active, not recruiting

Transversus Thoracic Muscle Plane Block for Open Heart Surgery

Conditions:   Pain, Acute;   Pain, Chest
Interventions:   Drug: Bupivacaine;   Drug: Saline
Sponsor:   Ataturk University
Recruiting

Effect of a Treatment With a Nutraceutical Combination on Sub-optimal LDL Cholesterol Levels

Condition:   Hypercholesterolemia
Interventions:   Dietary Supplement: Nutraceutical combination;   Other: Placebo
Sponsor:   A. Menarini Industrie Farmaceutiche Riunite S.r.l.
Completed

Effect of Evolocumab Added to Moderate-Intensity Statin Therapy on LDL-C Lowering and Cardiovascular Adverse Events in Patients With Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Intervention:   Drug: Evolocumab
Sponsor:   Tianjin Chest Hospital
Not yet recruiting

Assessing Force-velocity Profile: an Innovative Approach to Optimize Cardiac Rehabilitation in Coronary Patients

Condition:   Acute Coronary Syndrome
Interventions:   Other: Sprints;   Other: Vertical jumps;   Other: Questionary Short Form-12 (SF-12);   Device: activity actigraph;   Other: Program composed of two 2 training strategies;   Other: Program of usual practice
Sponsors:   Centre Hospitalier Universitaire de Saint Etienne;   Laboratoire SNA-EPIS - Université Jean Monnet
Recruiting

Improving Mitral Repair for Functional Mitral Regurgitation

Conditions:   Cardiomyopathy;   Cardiovascular Diseases;   Congestive Heart Failure;   Coronary Artery Disease;   Heart Disease;   Valvular Heart Disease;   Mitral Valve Disease
Interventions:   Procedure: Undersizing Mitral Annuloplasty;   Procedure: Papillary Muscle Approximation
Sponsors:   Emory University;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Three Fraction Accelerated Partial Breast Irradiation as the Sole Method of Radiation Therapy for Low-risk Stage 0 and I Breast Carcinoma

Conditions:   Breast Carcinoma;   Breast Cancer
Interventions:   Radiation: Three Fraction Accelerated Partial Breast Irradiation;   Procedure: Partial mastectomy
Sponsor:   Washington University School of Medicine
Recruiting

A Study of People With Type 2 Diabetes Who Have Diseases That Affect the Heart and Blood Vessels. The Study Will Also Look at the Treatment of a Group of These People in Hospitals in Portugal

Condition:   Diabetes Mellitus, Type 2
Intervention:   Other: No treatment given
Sponsor:   Novo Nordisk A/S
Enrolling by invitation

Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System

Condition:   CAD
Interventions:   Device: MRI scan x 1 Healthy Volunteer;   Device: MRI scan x 2 Healthy Volunteer;   Device: MRI scan x 2 - CAD patients;   Device: MRI scan x 2- non CAD patients
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy

Condition:   Node Positive HER2 Negative Breast Cancer
Interventions:   Other: Placebo;   Drug: Aspirin
Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI);   United States Department of Defense;   Bayer;   Canadian Cancer Trials Group
Recruiting

Adding Antiplatelet During Edoxaban Treatment in Stroke Patients With Non-valvular Atrial Fibrillation (ADD-ON)

Conditions:   Acute Ischemic Stroke;   Atrial Fibrillation;   Extracranial Atherosclerosis;   Intracranial Atherosclerosis;   Coronary Artery Atherosclerosis;   Peripheral Artery Stenosis;   Anticoagulant;   Antiplatelet
Intervention:   Drug: Edoxaban Monotherapy
Sponsors:   Asan Medical Center;   Samsung Medical Center;   Myongji Hospital;   Ewha Womans University;   Chonbuk National University;   Pusan National University Hospital;   Korea University;   Keimyung University Dongsan Medical Center;   Chonnam National University Hospital;   Korea University Guro Hospital;   Chungnam National University Hospital;   Chung-Ang University Hosptial, Chung-Ang University College of Medicine;   Kyungpook National University Hospital;   Dongtan Sacred Heart Hospital;   Eulji University Hospital
Recruiting

The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry

Conditions:   Spontaneous Coronary Artery Dissection;   SCAD
Intervention:  
Sponsor:   Mayo Clinic
Recruiting

Technical Development of Cardiovascular Magnetic Resonance Imaging

Conditions:   Cardiomyopathy;   Congenital Heart Disease;   Cardiovascular Disease;   Cardiac Magnetic Resonance Imaging;   Acute Myocardial Infarction
Intervention:   Device: Siemens MRI scanner
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Suspended

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.

Conditions:   Coronary Heart Disease;   Anemia;   Bronchial Asthma;   Stroke;   Epilepsy;   Parkinson's Disease;   Heart Rhythm Disorders;   Alzheimer's Disease;   Neuromuscular Diseases;   Diabetes;   Chronic Heart Failure;   Chronic Obstructive Pulmonary Disease;   Chronic Kidney Diseases
Intervention:  
Sponsors:   Russian Federation of Anesthesiologists and Reanimatologists;   Kuban State Medical University
Recruiting

The Study of Efficacy and Safety of Automated PD in Urgent Start Dialysis

Condition:   ESRD
Interventions:   Procedure: automated peritoneal dialysis;   Procedure: IHD
Sponsors:   Peking Union Medical College Hospital;   First Hospital of China Medical University;   Beijing Anzhen Hospital;   The Luhe Teaching Hospital of the Capital Medical University;   Ningbo No.2 Hospital
Recruiting

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

Conditions:   Acute Kidney Injury;   Renal Insufficiency, Chronic;   Heart Failure;   Myocardial Infarction;   Arrhythmias, Cardiac;   Stroke
Intervention:   Procedure: Transcatheter Aortic Valve Replacement
Sponsor:   University of Texas Southwestern Medical Center
Recruiting

Diastolic Dysfunction in Morbidly Obese Patients Undergo Bariatric Surgery

Conditions:   Diastolic Dysfunction;   Morbid Obesity
Intervention:  
Sponsor:   Mahidol University
Not yet recruiting

Outpatient Cardiac Tele-Rehabilitation in a Public Sports Center

Conditions:   Acute Coronary Syndrome;   Cardiac Rehabilitation;   Telerehabilitation;   Secondary Prevention;   Wearable Electronic Devices;   Exercise Therapy
Intervention:   Procedure: Cardiac Rehabilitation
Sponsor:   Juan Izquierdo García
Recruiting

The Combined Portfolio Diet and Exercise Study

Conditions:   Cardiovascular Diseases;   Hypercholesterolemia;   Type 2 Diabetes;   Metabolic Syndrome
Interventions:   Behavioral: Portfolio diet and structured exercise;   Behavioral: DASH-like diet and structured exercise;   Behavioral: Portfolio diet and routine exercise;   Behavioral: DASH-like diet and routine exercise
Sponsors:   St. Michael's Hospital, Toronto;   Canadian Institutes of Health Research (CIHR);   University of Toronto;   Laval University;   University of Manitoba;   University of British Columbia
Recruiting

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Active, not recruiting

Non-Interventional Study on Effectiveness of Elxaban Tab. in Patients With Non-valvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Yonsei University
Active, not recruiting

Use of Prothrombin Complex Concentrate in Patients Admitted in Emergency Care Units for Severe Bleeding While Receiving Oral Anticoagulants

Condition:   Emergency Care for Severe Bleeding While on Anticoagulants
Interventions:   Other: Expert eCRF;   Other: Prothrombin Complex Concentrate
Sponsor:   Octapharma
Recruiting

The NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion

Conditions:   Chronic Total Occlusion of Coronary Artery;   Heart Failure;   Angina Pectoris
Intervention:   Procedure: CTO PCI
Sponsor:   Leif Thuesen
Recruiting

Does a Complex Care Discharge Planning Initiative Reduce Unplanned Hospital Readmissions? (G78717-Readmits)

Condition:   Patient Readmission
Intervention:   Other: Policy intervention
Sponsor:   University of British Columbia
Recruiting

Intervention of Air Pollution and Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:   Device: mask
Sponsor:   Peking University
Recruiting

Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock.

Condition:   Cardiogenic Shock
Interventions:   Combination Product: Hydrocortisone + Flucortac;   Other: Placebo
Sponsor:   CMC Ambroise Paré
Recruiting

Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Biological: Apolipoprotein A-I [human] (apoA-I);   Other: Placebo
Sponsor:   CSL Behring
Recruiting

Radiotherapy in Preoperative Setting With CyberKnife for Breast Cancer

Condition:   Early Breast Cancer
Intervention:   Radiation: Neoadjuvant radiotherapy
Sponsor:   Azienda Ospedaliero-Universitaria Careggi
Recruiting

Prehospital Translation of Chest Pain Tools

Conditions:   Acute Coronary Syndrome;   Pulmonary Embolism
Intervention:   Other: Data Collection
Sponsors:   Wake Forest University Health Sciences;   Cape Fear Valley Mobile Integrated Healthcare Cumberland County EMS;   New Hanover Regional Medical Center EMS
Completed

HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program

Conditions:   Myocardial Infarction;   Acute Coronary Syndrome;   ST-segment Elevation Myocardial Infarction (STEMI);   Non-ST-Segment Elevation Myocardial Infarction (NSTEMI);   Angina, Stable
Intervention:   Behavioral: HeartHome
Sponsors:   University of North Carolina, Chapel Hill;   Duke University
Not yet recruiting

Differential Expression and Analysis of Peripheral Plasma Exosome miRNA in Patients With Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Other: exosome
Sponsor:   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Not yet recruiting

Prospective Multicenter Study for Early Evaluation of Acute Chest Pain

Conditions:   Chest Pain;   Acute Aortic Dissection;   Pulmonary Embolism;   Acute Myocardial Infarction Type 1;   Acute Coronary Syndrome
Interventions:   Diagnostic Test: Coronary angiography;   Diagnostic Test: CT angiography of aorta;   Diagnostic Test: CT angiography of pulmonary arteries.;   Diagnostic Test: Electrocardiogram;   Diagnostic Test: Cardiac Troponin
Sponsor:   West China Hospital
Not yet recruiting

Clinical Performance and Quality Measures for Adults With Acute ST-Elevation Myocardial Infarction in China

Condition:   ST Elevation Myocardial Infarction
Intervention:   Behavioral: Quality improvement strategies and tools
Sponsor:   China National Center for Cardiovascular Diseases
Recruiting

Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry

Condition:   Myocardial Infarction
Intervention:  
Sponsors:   Duke University;   Chiesi Farmaceutici S.p.A.
Recruiting

Improve SCA Bridge Study

Conditions:   Sudden Cardiac Arrest;   Acute Myocardial Infarction
Interventions:   Behavioral: EP referred group;   Behavioral: Non-Referred group
Sponsor:   Medtronic Cardiac Rhythm and Heart Failure
Recruiting

TREatment With Beta-blockers After myOcardial Infarction withOut Reduced Ejection fracTion"

Condition:   Myocardial Infarction
Intervention:   Drug: Beta blocker
Sponsor:   Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Recruiting

A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction

Condition:   ST Elevation Myocardial Infarction
Interventions:   Biological: MEDI6012;   Other: Placebo
Sponsors:   MedImmune LLC;   Thrombolysis in Myocardial Infarction (TIMI) Study Group
Recruiting

The Effect of Opioids on P2Y12 Receptor Inhibition in Patients With ST-Elevation Myocardial Infarction Who Are Pre-treated With Crushed Ticagrelor

Conditions:   STEMI;   STEMI - ST Elevation Myocardial Infarction
Interventions:   Drug: Paracetamol;   Drug: Fentanyl
Sponsors:   A.H. Tavenier;   Isala
Recruiting

Brilinta Clinical Experience Investigation

Condition:   Acute Coronary Syndrome, Old Myocardial Infarction
Intervention:  
Sponsor:   AstraZeneca
Recruiting

Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI

Condition:   Acute Myocardial Infarction
Interventions:   Drug: LCZ696 (sacubitril/valsartan);   Drug: Ramipril;   Drug: Placebo of LCZ696;   Drug: Placebo of ramipril;   Drug: Valsartan;   Drug: Placebo of valsartan
Sponsor:   Novartis Pharmaceuticals
Recruiting

High-Intensity Interval Training Early After Left Ventricular Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Other: HIIT;   Other: MICE
Sponsor:   University Hospital Inselspital, Berne
Recruiting

Clinical Study of Extra-Corporal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction

Condition:   Cardiogenic Shock
Intervention:   Device: Extra-Corporal Life Support (ECLS)
Sponsor:   Klinikum der Universitaet Muenchen
Completed

BIO monitorinG in Patients With Preserved Left ventricUlar Function AfteR Diagnosed Myocardial Infarction

Conditions:   Myocardial Infarction;   Myocardial Infarction, Acute;   Myocardial Infarction Old
Intervention:   Device: BioMonitor
Sponsor:   Biotronik SE & Co. KG
Recruiting

Aerobic Trainings on Stroke Patients

Condition:   Stroke, Cardiovascular
Intervention:   Behavioral: Aerobic exercise training
Sponsor:   Chang Gung Memorial Hospital
Completed

INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart Failure

Conditions:   Heart Failure;   Myocardial Infarction
Interventions:   Biological: High Dose Trivalent Influenza Vaccine;   Biological: Standard Dose Quadrivalent Influenza Vaccine
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   University of Wisconsin, Madison;   University of Toronto;   Boston VA Research Institute, Inc.;   Patient-Centered Outcomes Research Institute
Active, not recruiting

Sleep Study-Guided Multidisciplinary Therapy for Patients Presenting With Acute Coronary Syndrome

Conditions:   Obstructive Sleep Apnea;   Acute Coronary Syndrome
Interventions:   Device: Continuous Positive Airway Therapy;   Behavioral: Sleep-Study Guided Multidisciplinary Therapy
Sponsor:   National University, Singapore
Active, not recruiting

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Conditions:   Acute Coronary Syndrome;   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin;   Drug: Antiplatelet drugs
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Research & Development, LLC
Active, not recruiting