Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Effect and Efficacy of Xpedition™/Alpine™, Everolimus-eluting Stent for Coronary Atherosclerosis

Conditions:   Coronary Artery Disease;   Percutaneous Coronary Intervention;   Acute Coronary Syndrome;   Angina Pectoris
Intervention:   Device: Alpine
Sponsors:   Seoul National University Hospital;   Abbott
Recruiting - verified July 2016

Hemodynamic Responses of Stable Ischemic Heart Disease Patients to a Comedy Session

Condition:   Ischaemic Heart Disease
Interventions:   Other: Group Treatment;   Other: Group Control
Sponsor:   Hospital de Clinicas de Porto Alegre
Recruiting - verified July 2016

Aspirin Desensitization Registry in Patients With Aspirin Hypersensitivity

Condition:   Aspirin Hypersensitivity
Intervention:   Drug: aspirin
Sponsor:   Italian Society of Cardiology
Completed - verified July 2016

Improving Sleep for Healthy Hearts

Conditions:   Insomnia;   Coronary Heart Disease
Interventions:   Behavioral: Go! to Sleep;   Behavioral: General Sleep Education
Sponsors:   Brigham and Women's Hospital;   The Cleveland Clinic
Active, not recruiting - verified July 2016

Myocardial Flow Reserve and 99mTc-DTPA Cardiac Dynamic SPECT

Condition:   Coronary Artery Disease
Intervention:   Other: Cardiac SPECT
Sponsor:   University Hospital, Caen
Not yet recruiting - verified July 2016

Smart Phone Application in the Secondary Clinical Prevention Management for Chinese Patients

Condition:   Coronary Disease
Interventions:   Device: smart phone app;   Device: A guideline booklet
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Not yet recruiting - verified April 2016

Influence of Different Forms of Exercise Training in Patients With Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Other: water-based exercise training;   Other: land-based exercise training
Sponsors:   University Medical Centre Ljubljana;   KRKA
Recruiting - verified July 2016

High Intensity Lipid Lowering Following Acute Coronary Syndromes for Persons Living With HIV

Conditions:   HIV Infection;   Coronary Heart Disease
Interventions:   Drug: Pravastatin;   Drug: Rosuvastatin
Sponsor:   Donald Lloyd-Jones
Not yet recruiting - verified July 2016

Intravascular Ultrasound Prediction of Myocardial Size and Coronary Computed Tomography-Derived Ischemic Burden for Coronary Lesion

Condition:   Coronary Artery Disease
Intervention:   Other: Intravascular Ultrasound, coronary computed tomography angiography
Sponsors:   Asan Medical Center;   Boston Scientific Corporation
Not yet recruiting - verified July 2016

Galaxy Rapamycin Drug-Eluting Bioresorbable Coronary Stent System First-in-man Study

Condition:   Heart Diseases
Intervention:   Device: Rapamycin Drug-Eluting Bioresorbable Coronary Stent System
Sponsor:   Shanghai Bio-heart Biological Technology Co., Ltd.
Not yet recruiting - verified July 2016

Implantable Cardioverter Defibrillator Versus Optimal Medical Therapy In Patients With Variant Angina Manifesting as Aborted Sudden Cardiac Death

Conditions:   Angina Pectoris, Variant;   Sudden Cardiac Death
Interventions:   Device: Implantable Cardioverter Defibrillator;   Drug: Optimal Medical Therapy
Sponsors:   Kee-joon Choi;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2016

Evaluation of the Capacity of a Camera to Identify Signs of Arteriosclerosis in Retinal Arterioles

Condition:   Arteriosclerosis
Intervention:   Device: MHRC: Metabolic Hyperspectral Retinal Camera
Sponsors:   Dr. Jean-Claude Tardif;   Montreal Heart Institute;   Polytechnique Montréal
Not yet recruiting - verified July 2016

Long-term Remote Ischemic Preconditioning Improve Long-term Prognosis of Acute Myocardial Infarction Patients Without Emergency Reperfusion Therapy

Condition:   Myocardial Infarction [C14.280.647.500]
Intervention:   Other: reported remote ischemic preconditioning (RIPC)
Sponsor:   Xuanwu Hospital, Beijing
Not yet recruiting - verified July 2016

Reactive Oxygen Species Following Aortic Valve Replacement

Condition:   Aortic Stenosis
Intervention:  
Sponsor:   University Hospital Southampton NHS Foundation Trust.
Recruiting - verified July 2016

Evaluation of Soluble ST2 in Patients Receiving Primary PCI With ST-elevation Myocardial Infarction

Conditions:   Myocardial Infarction;   Shock
Intervention:  
Sponsor:   Wuhan Asia Heart Hospital
Recruiting - verified July 2016

SYNTAX III REVOLUTION Trial: A Randomized Study Investigating the Use of CT Scan and Angiography of the Heart to Help the Doctors Decide Which Method is the Best to Improve Blood Supply to the Heart in Patients With Complex Coronary Artery Disease

Conditions:   Coronary Artery Diseases;   Multivessel Coronary Artery Disease;   Heart Diseases;   Cardiovascular Diseases
Interventions:   Radiation: Coronary Angiography;   Radiation: Computed Tomography (CT) scan
Sponsors:   ECRI bv;   GE Healthcare;   HeartFlow, Inc.
Not yet recruiting - verified July 2016

Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years

Conditions:   Acute Myocardial Infarction;   Pulmonary Embolism;   Aortic Dissection
Intervention:  
Sponsor:   Qilu Hospital
Recruiting - verified July 2016

Increasing Risk Perception of Physical Activity Using Patient-targeted Feedback.

Conditions:   Hypertension;   Coronary Disease;   Cardiac Diseases
Interventions:   Behavioral: Patient-targeted individual physical-activity-feedback;   Device: Pedometer
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Not yet recruiting - verified July 2016

Ad-HGF Treatment for Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Drug: Ad-HGF;   Other: 0.9% NaCl
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Not yet recruiting - verified June 2016

A Randomized Comparison of Clinical Outcomes Between Everolimus-eluting Bioresorbable Vascular Scaffold Versus Everolimus-eluting Metallic Stent in Long Coronary Lesions

Condition:   Coronary Artery Disease
Interventions:   Device: PCI with Absorb everolimus-eluting bioresorbable vascular scaffold;   Device: PCI with Xience everolimus-eluting metallic stent
Sponsor:   Yonsei University
Recruiting - verified July 2016

Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension

Condition:   Hypertension Resistant to Conventional Therapy
Interventions:   Drug: Spironolactone;   Drug: Furosemide,;   Drug: Amiloride;   Drug: Ramipril;   Drug: Bisoprolol
Sponsor:   Sao Jose do Rio Preto University
Recruiting - verified July 2016

Intra-patient Study With Polymer Free Drug Eluting Stent Versus Abluminal Biodegradable Polymer Drug Eluting Stent With Early OCT (Optical Coherence Tomography) Follow up

Condition:   Coronary Artery Disease
Interventions:   Device: Coroflex® ISAR Drug-eluting stent;   Device: Ultimaster® Drug-eluting stent
Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   B.Braun Surgical SA
Recruiting - verified July 2016

CT COMPARE: CT COronary Angiography to Measure PlAque REduction

Condition:   Cardiovascular Disease
Interventions:   Drug: Rosuvastatin;   Drug: Atorvastatin
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified July 2016

Clinical Study of Medicinal Product Cardionat® Using in Health Athlete Volunteers

Conditions:   Stroke, Not Specified as Hemorrhage or Infarction;   Angina Pectoris
Intervention:   Drug: оral intake of study drug capsules; study drug - Cardionat ® (trimethylhydrazinium propionate dihydrate), oral capsules 250 mg
Sponsor:   Burnasyan Federal Medical Biophysical Center
Recruiting - verified April 2016

Plasma GLP1 and Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention

Conditions:   Coronary Angiography;   Glucagon-Like Peptide 1
Intervention:  
Sponsor:   Chinese PLA General Hospital
Recruiting - verified July 2016

A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL_112;   Other: Placebo
Sponsor:   CSL Behring
Not yet recruiting - verified July 2016

FGF21 Can Help Predicting Arterial Stiffness Measured by Cardio-ankle Vascular Index in Renal Transplant Patients

Condition:   Vascular Stiffness
Intervention:   Other: CAVI and FGF-21
Sponsor:   Bangkok Metropolitan Administration Medical College and Vajira Hospital
Completed - verified July 2016

Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications

Conditions:   Myocardial Ischemia;   Rheumatic Diseases
Intervention:   Other: Caplan IVR
Sponsor:   VA Office of Research and Development
Not yet recruiting - verified July 2016

PARA-HEART Pilot Implementation

Conditions:   Acute Coronary Syndrome;   Chest Pain
Intervention:  
Sponsor:   Wake Forest Baptist Health
Not yet recruiting - verified July 2016

Mental Stress Ischemia: Biofeedback Study

Conditions:   Cardiovascular Disease;   Coronary Artery Disease
Interventions:   Behavioral: Heart Rate Variability (HRV) Biofeedback (BF);   Other: Mental Stress Protocol
Sponsor:   Emory University
Recruiting - verified July 2016

Fractional Flow Reserve Versus Angiography for Guiding Selective Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction

Conditions:   Fractional Flow Reserve;   ST-segment Elevation Myocardial Infarction;   Percutaneous Coronary Intervention
Intervention:  
Sponsor:   Nanjing Medical University
Enrolling by invitation - verified January 2016

Comparative Effectiveness of Decision Aids for Stable Chest Discomfort

Conditions:   Coronary Artery Disease;   Stable Angina
Interventions:   Behavioral: Online decision aid;   Behavioral: Video decision aid
Sponsor:   Massachusetts General Hospital
Active, not recruiting - verified July 2016

Remote Ischaemic Conditioning and Coronary Endothelial Function (RIC-COR)

Conditions:   Ischemic Preconditioning;   Coronary Disease
Interventions:   Procedure: Remote ischaemic conditioning;   Procedure: Arm cuff placement, no inflation;
Sponsors:   NHS National Waiting Times Centre Board;   University of Glasgow;   Chest, Heart and Stroke Association Scotland;   Chief Scientist Office of the Scottish Government
Completed - verified July 2016

Shockwave Coronary Rx Lithoplasty® Study

Condition:   Coronary Artery Disease
Intervention:   Device: Shockwave Medical Coronary Rx Lithoplasty System
Sponsor:   Shockwave Medical, Inc.
Recruiting - verified June 2016

The Physiological Impact of CTO PCI on Coronary Pressure Measurements and Correlation in Donor Vessel

Conditions:   Acute Coronary Syndrome;   Coronary Artery Disease
Intervention:  
Sponsor:   Basildon and Thurrock University Hospitals NHS Foundation Trust
Recruiting - verified July 2016

Short-term Air Pollution Exposure and In-hospital Outcomes in Patients With Acute Myocardial Infraction

Conditions:   Air Pollution;   Acute Myocardial Infarction;   Percutaneous Coronary Intervention
Intervention:  
Sponsors:   Nanjing Medical University;   The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Enrolling by invitation - verified July 2016

Anti-inflammatory Effect of Therapeutic Hypothermia in Acute Myocardial Infarction Complicated With Cardiogenic Shock

Condition:   Cardiac Arrest
Intervention:   Device: Therapeutic hypothermia
Sponsor:   China Medical University Hospital
Recruiting - verified July 2016

Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics, of MEDI6012 in Subjects With Stable Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Biological: MEDI6012;   Biological: Placebo
Sponsor:   MedImmune LLC
Recruiting - verified July 2016

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified July 2016

Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD

Conditions:   Diabetes Mellitus, Type 2;   Coronary Artery Disease;   Cardiovascular Diseases
Interventions:   Drug: RVX000222;   Drug: Placebo (for RVX000222);   Drug: atorvastatin;   Drug: rosuvastatin
Sponsors:   Resverlogix Corp;   PPD;   ICON plc;   Medidata Solutions
Recruiting - verified July 2016

Analysis of Surface EKG Signals to Identify Myocardial Dysfunction in Patients at Risk for Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Device: MyoVista device;   Device: Computed tomographic coronary angiography;   Device: Transthoracic Echocardiography
Sponsors:   Icahn School of Medicine at Mount Sinai;   Heart Test Laboratories Inc.
Recruiting - verified July 2016

Treadmill CV Safety Study

Condition:   Stable Angina
Interventions:   Drug: AMG 334;   Drug: Placebo
Sponsor:   Amgen
Recruiting - verified July 2016

Atorvastatin Effectiveness and Safety in Cardiology Patients in Real World Setting

Condition:   Coronary Artery Disease, Hypercholesterolemia, Hypertension
Intervention:   Other: No intervention
Sponsor:   Pfizer
Not yet recruiting - verified July 2016

Comparison of Loading Strategies With Antiplatelet Drugs in Patients Undergoing Elective Coronary Intervention

Condition:   Angina Pectoris
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel
Sponsor:   Klinikum der Universitaet Muenchen
Recruiting - verified July 2016

Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-142

Condition:   Coronary Artery Disease
Intervention:   Drug: sulphur hexafluoride lipid-type A microspheres
Sponsor:   Bracco Diagnostics, Inc
Recruiting - verified July 2016

Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery

Conditions:   Hypotension;   Postoperative Complications;   Acute Coronary Syndrome;   Heart Failure;   Coronary Occlusion;   Stroke;   Acute Kidney Injury;   Renal Insufficiency, Chronic;   Death
Interventions:   Drug: Liberal blood pressure management;   Drug: Tight blood pressure management
Sponsor:   Miodrag Filipovic, Prof. Dr. med.
Recruiting - verified July 2016

ComparisoN of ticAgrelor vs. Clopidogrel in endoTHeliAl Function of COPD patieNts

Conditions:   Coronary Artery Disease;   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Aspirin 100 mg;   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   University Hospital of Ferrara
Active, not recruiting - verified May 2016

Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-141

Condition:   Coronary Artery Disease
Intervention:   Drug: sulphur hexafluoride lipid-type A microspheres
Sponsor:   Bracco Diagnostics, Inc
Recruiting - verified July 2016

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified July 2016

Clinical Usefulness of Fractional Flow Reserve Measurement for Significant Stenosis in Proximal Coronary Artery

Conditions:   Coronary Artery Disease;   Stenosis
Intervention:  
Sponsor:   Yonsei University
Completed - verified July 2016

Copeptin Registry (proCORE) Biomarkers in Cardiology (BIC)-19

Condition:   Acute Myocardial Infarction
Intervention:   Procedure: Routine management observation
Sponsor:   Charite University, Berlin, Germany
Recruiting - verified July 2016

A Comparison of Optical Coherence Tomography Guidance and Angiography-only Guidance for Percutaneous Coronary Intervention With Bioresorbable Vascular Scaffold

Condition:   Coronary Artery Disease
Interventions:   Device: Angiography-guided PCI with bioresorbable vascular scaffold;   Device: optical coherence tomography-guided PCI with bioresorbable vascular scaffold
Sponsor:   Yonsei University
Completed - verified July 2016

Stress Ulcer Prophylaxis in the Intensive Care Unit

Conditions:   Gastrointestinal Bleeding;   Stress Ulcers
Interventions:   Drug: Pantoprazole;   Other: Saline (0.9%)
Sponsors:   Dr. Morten Hylander Møller;   Rigshospitalet, Denmark;   Copenhagen Trial Unit, Center for Clinical Intervention Research
Recruiting - verified July 2016

Current Treatment Strategy of Patients With Multivessel Disease or Left Main Coronary Artery Disease Indicated for Coronary Artery Bypass Graft Surgery

Condition:   Coronary Artery Disease
Intervention:   Procedure: CABG surgery
Sponsor:   Yonsei University
Recruiting - verified July 2016

A Multicenter Trial to Assess the MIcrovascular Integrity and Left Ventricular Function Recovery After Clopidogrel or TicagrelOr Administration, in Patients With STEMI Treated With Thrombolysis - The 'MIRTOS' Study

Conditions:   Myocardial Infarction;   ST Segment Elevation Myocardial Infarction (STEMI)
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel;   Procedure: Percutaneous Coronary Intervention (PCI);   Procedure: Coronary Angiography
Sponsor:   Hellenic Cardiovascular Research Society
Recruiting - verified July 2016

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Harvard Clinical Research Institute;   Medstar Research Institute
Active, not recruiting - verified July 2016

Validation of Simple Acute Coronary Syndrome (SACS) Score

Conditions:   Chest Pain;   Acute Coronary Syndrome;   Angina;   Myocardial Infarction
Intervention:  
Sponsors:   Bayfront Health St Petersburg;   Bayfront Health Dade City;   Community Health Systems (CHS)
Enrolling by invitation - verified July 2016

Statins at the Primary Care Level

Condition:   Dyslipidemia
Intervention:   Other: Educational Intervention
Sponsor:   Institute for Clinical Effectiveness and Health Policy
Active, not recruiting - verified July 2016

Effectiveness of an E-health Educational Intervention for Cardiovascular Disease Adults in Improving Outcomes

Condition:   Cardiovascular Disease
Intervention:   Behavioral: e-health educational intervention (eHEI)
Sponsor:   Chinese University of Hong Kong
Completed - verified July 2016

China PEACE II: Quality Improvement for Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Behavioral: Quality improvement strategies and tools;   Behavioral: Process optimization
Sponsor:   China National Center for Cardiovascular Diseases
Active, not recruiting - verified July 2016

Combined Coronary and Cerebral Angiography and Intervention for Coronary and Cerebrovascular Atherosclerosis

Conditions:   Coronary Stenosis;   Cerebral Stenosis
Interventions:   Other: simultaneous coronary and cerebral intervention;   Other: staged coronary and cerebral intervention
Sponsor:   Capital Medical University
Recruiting - verified July 2016

A High-Resolution Magnetic Resonance Imaging Study to Evaluate the Effect of Rosuvastatin on Carotid Atherosclerotic Plaques

Conditions:   Arteriosclerosis;   Diabetes Mellitus;   Lipid Disorder
Interventions:   Drug: Rosuvastatin 5mg;   Drug: Rosuvastatin 20mg
Sponsor:   Capital Medical University
Recruiting - verified July 2016

Sonolysis in Risk Reduction of Symptomatic and Silent Brain Infarctions During Coronary Stenting

Condition:   Coronary Artery Disease
Interventions:   Device: Sonolysis;   Other: Sham procedure
Sponsor:   University Hospital Ostrava
Recruiting - verified July 2016

ILUMIEN III: OPTIMIZE PCI

Condition:   Coronary Artery Disease
Interventions:   Procedure: Coronary PCI guided by IVUS;   Procedure: Coronary PCI guided by OCT;   Procedure: Coronary PCI guided by Angiography
Sponsors:   St. Jude Medical;   Cardiovascular Research Foundation, New York
Active, not recruiting - verified July 2016

CCC Project- Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   Beijing Institute of Heart, Lung and Blood Vessel Diseases;   American Heart Association;   Chinese Society of Cardiology
Recruiting - verified July 2016

A Study of VentriGel in Early and Late Post-myocardial Infarction Patients

Conditions:   Myocardial Infarction;   Heart Failure;   Left Ventricular Remodeling
Intervention:   Biological: VentriGel
Sponsor:   Ventrix, Inc.
Enrolling by invitation - verified July 2016

Nutrition, Inflammation and Insulin Resistance in End Stage Renal Disease-Aim 2

Condition:   ESRD
Interventions:   Drug: anakinra;   Drug: actos;   Other: placebo
Sponsor:   VA Office of Research and Development
Recruiting - verified July 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified July 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Dexmedetomidine and Outcomes of Cardiac Surgery (DOCS)

Conditions:   Heart Valve Diseases;;   Cardiac Valve Replacement Complication;;   Coronary Artery Disease
Interventions:   Drug: dexmedetomidine;   Drug: placebo
Sponsor:   Xijing Hospital
Recruiting - verified July 2016

GISSI Outliers CAPIRE

Condition:   Atherosclerosis
Intervention:  
Sponsor:   Gruppo di Ricerca GISSI
Active, not recruiting - verified July 2016

COmparison and Modification in Neointimal Pattern Assessed by Optical Coherence Tomography With High Versus Moderate Efficacy Statin Treatment After Drug Eluting Stent Implantation: COMPASS Trial

Condition:   Coronary Artery Disease
Interventions:   Drug: Atorvastatin 40mg;   Drug: pravastatin 20 mg
Sponsor:   Yonsei University
Completed - verified July 2016

Rubidium Elution System Performance Testing

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Jubilant DraxImage Inc.
Recruiting - verified July 2016

ASV for Sleep Apnea After Myocardial Infarction

Conditions:   Acute Myocardial Infarction;   Sleep Apnea
Intervention:   Device: Adaptive servo-ventilation
Sponsors:   University Hospital Regensburg;   ResMed Foundation
Recruiting - verified July 2016

Obtain Additional Information on Use of CorMatrix ECM (Extracellular Matrix)

Condition:   Coronary Disease
Intervention:  
Sponsor:   CorMatrix
Enrolling by invitation - verified July 2016

Aortic Valve and Root Measurements Under Real-Time 3-Dimensional Visualization During Angiography

Conditions:   Coronary Artery Disease;   Aortic Stenosis
Intervention:   Radiation: Real-time 3-dimensional DynaCT
Sponsor:   Binita Shah
Recruiting - verified July 2016

Revascularisation or Medical Therapy in Elderly Patients With Acute Anginal Syndromes

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Conservative Arm;   Procedure: Invasive Arm
Sponsors:   Brighton and Sussex University Hospitals NHS Trust;   Medtronic Vascular
Recruiting - verified July 2016

IRIS-PREMIER REGISTRY

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Coronary Disease;   Heart Diseases
Intervention:   Device: Promus PREMIER
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea;   Boston Scientific Korea Co. Ltd
Active, not recruiting - verified July 2016

Detection and Significance of Heart Injury in ST Elevation Myocardial Infarction.

Condition:   Acute ST-elevation Myocardial Infarction
Interventions:   Device: Coronary pressure wire;   Other: Magnetic resonance imaging of the heart
Sponsors:   NHS National Waiting Times Centre Board;   Siemens Healthcare Diagnostics Inc;   British Heart Foundation
Active, not recruiting - verified July 2016

Study of Effects of Ticagrelor on Microparticles and Micro-RNA in NSTE-ACS

Condition:   Non ST Segment Elevation Acute Coronary Syndrome
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   Catholic University of the Sacred Heart
Terminated - verified July 2016

Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis

Condition:   Saphenous Vein Graft Disease
Interventions:   Drug: Aspirin;   Drug: Ticagrelor
Sponsors:   Boca Raton Regional Hospital;   AstraZeneca;   Ottawa Heart Institute Research Corporation
Recruiting - verified July 2016

Wall Shear Stress and Neointimal Healing Following PCI in Angulated Coronary Vessels

Condition:   Coronary Artery Disease
Interventions:   Device: Resolute Integrity Zotarolimus eluting stent;   Device: Xience Xpedition everolimus eluting stent
Sponsors:   Emory University;   Medtronic
Recruiting - verified July 2016

Verification of the Safety of Early Discharge in Patients After Acute ST-segment Myocardial Infarction

Conditions:   Coronary Artery Disease;   Acute Myocardial Infarction With ST-segment Elevation;   Primary Percutaneous Coronary Intervention;   Early Discharge
Interventions:   Other: Early discharge;   Other: Standard discharge
Sponsor:   Kamil Novobílský
Recruiting - verified July 2016

Is Our Microbiome a Predictor of Cardiac Risk

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Mayo Clinic
Recruiting - verified April 2016

Comparison of Depression Identification After Acute Coronary Syndrome: Quality of Life and Cost Outcomes

Conditions:   Acute Coronary Syndrome;   Depressive Symptoms
Interventions:   Other: Cognitive Behavioral Therapy (CBT);   Drug: Antidepressant Medication;   Other: Standard Care;   Other: Depressive symptom screener;   Other: No intervention
Sponsors:   Columbia University;   National Heart, Lung, and Blood Institute (NHLBI);   Duke University;   HealthPartners Institute;   Kaiser Foundation Research Institute
Recruiting - verified July 2016

STem cElls Mobilization in Acute Myocardial Infarction Outcome Trial

Conditions:   Anterior Acute Myocardial Infarction;   Left Ventricular Systolic Dysfunction
Intervention:   Drug: G-CSF administration
Sponsors:   Heart Care Foundation;   A. Manzoni Hospital;   Centro Cardiologico Monzino
Suspended - verified March 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified July 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified July 2016

Study of Efficacy and Safety of Percutaneous Coronary Intervention to Improve Survival in Heart Failure

Condition:   Ischemic Cardiomyopathy
Interventions:   Procedure: Percutaneous Coronary Intervention;   Drug: Drug Therapy for Heart Failure;   Device: Device Therapy for Heart Failure
Sponsors:   King's College London;   National Institute for Health Research, United Kingdom;   London School of Hygiene and Tropical Medicine (Clinical Trials Unit);   University of York;   Guy's and St Thomas' NHS Foundation Trust
Recruiting - verified July 2016

ROOBY Trial Follow-up Extension

Conditions:   All Cause Mortality;   MACE
Intervention:  
Sponsor:   VA Office of Research and Development
Active, not recruiting - verified July 2016

Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Recruiting - verified July 2016

Serial EValuation of multiplE Coronary Artery Diseases by an Optical Coherence Tomography; Assessment of the Changes of de Novo Lesions and Comparisons of Neointimal Coverage Between Xience Prime® Versus Cypher SelectTM Stents; SEVEN-Xience Study

Condition:   Multi-vessel Diseases, Angina
Interventions:   Device: Sirolimus-eluting stent (Cypher SelectTM, Cordis, Miami, FL);   Device: Everolimus-eluting stent(Xience Prime®, Abbott Vascular, Santa Claea, CA);   Drug: Pravastatin 20mg;   Drug: Atorvastatin 40mg
Sponsor:   Yonsei University
Completed - verified July 2016

Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients With Non ST Elevation Elevation Acute Coronary Syndrome

Conditions:   Non ST Elevation Myocardial Infarction;   Unstable Angina
Intervention:   Procedure: Invasive management
Sponsors:   NHS National Waiting Times Centre Board;   University of Glasgow
Completed - verified July 2016

Reintervention-study After Previous Renal Denervation in Non-responding Patients With Severe Hypertension

Condition:   Hypertension, Resistant to Conventional Therapy
Intervention:   Procedure: Renal Denervation
Sponsor:   Cardiovascular Center Frankfurt
Completed - verified July 2016

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound

Condition:   Hypercholesterolemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo
Sponsor:   Amgen
Active, not recruiting - verified July 2016

Revascularization Strategies for STEMI; The CMR Endpoint Study

Condition:   Acute Myocardial Infarction
Interventions:   Procedure: IRA-PCI;   Procedure: SS-PCI
Sponsor:   St. Michael's Hospital, Toronto
Recruiting - verified July 2016

Identify Clinical Conditions That Increase Circulating DNA Levels

Conditions:   Pregnancy;   Pulmonary Embolism;   Myocardial Infarction;   Autoimmune Disease
Intervention:   Other: One time blood draw to look at patient's DNA
Sponsor:   University of Florida
Active, not recruiting - verified July 2016

BLeeding Events and Maintenance DoSe of PraSugrel

Conditions:   Adverse Reaction to Antiplatelet Agent;   Acute Coronary Syndrome
Interventions:   Drug: Prasugrel dose 5 mg/day;   Drug: Prasugrel dose 10 mg/day
Sponsors:   David Antoniucci;   A.R. CARD Onlus Foundation
Terminated - verified July 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified July 2016

Fractional Flow Reserve Versus Angiographically Guided Management to Optimise Outcomes in Unstable Coronary Syndromes

Conditions:   Non-ST Elevation Myocardial Infarction.;   Type 1 Myocardial Infarction.
Intervention:   Device: Fractional flow reserve
Sponsors:   NHS National Waiting Times Centre Board;   British Heart Foundation;   St. Jude Medical;   University of Glasgow
Active, not recruiting - verified July 2016

Anti-inflammatory Effects of Colchicine in PCI

Condition:   Coronary Artery Disease
Interventions:   Drug: Colchicine;   Drug: Placebo
Sponsors:   New York University School of Medicine;   Takeda
Recruiting - verified July 2016

A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System

Conditions:   Congestive Heart Failure;   Left Ventricular (LV) Systolic Dysfunction
Intervention:   Device: CardioKinetix Parachute Implant and All Appropriate Medical Therapy (AAMT)
Sponsor:   CardioKinetix, Inc
Recruiting - verified July 2016

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified July 2016

Stem Cell Injection to Treat Heart Damage During Open Heart Surgery

Conditions:   Heart Disease;   Ischemic Heart Disease;   Coronary Artery Disease;   Coronary Artery Disease (CAD)
Intervention:   Other: Cell Therapy
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   NIH Heart Center at Suburban Hospital
Recruiting - verified July 2016

The Supplementary Role of Non-invasive Imaging to Routine Clinical Practice in Suspected Non-ST-elevation Myocardial Infarction

Conditions:   Chest Pain;   Myocardial Infarction;   Acute Coronary Syndrome;   Coronary Artery Disease;   Myocardial Ischemia
Interventions:   Other: Cardiovascular Magnetic Resonance Imaging;   Other: Computed Tomography Angiography
Sponsors:   Maastricht University Medical Center;   Dutch Heart Foundation
Active, not recruiting - verified July 2016

Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patients

Condition:   Endstage Kidney Disease
Interventions:   Drug: Vitamin K1;   Drug: Chrystalline Lactose
Sponsors:   Dr. Rachel Holden;   Kingston General Hospital
Recruiting - verified July 2016

Neointimal Coverage After Implantation of Biolimus Eluting Stent With Biodegradable Polymer: Optical Coherence Tomographic Assessment According to the Treatment of Dyslipidemia and Hypertension and the Types of Implanted Drug-eluting Stents

Condition:   Stable Angina or Acute Coronary Syndrome Considered for Percutaneous Coronary Intervention With Dyslipidemia or Hypertension
Interventions:   Device: Sirolimus-eluting stent;   Device: Biolimus-eluting stents;   Drug: pravastatin 20mg/day after DES implantation;   Drug: pitavastatin 2mg/day after DES implantation;   Drug: Non-ARB /day after DES implantation;   Drug: Eposartan 600mg/day after DES implantation
Sponsor:   Yonsei University
Completed - verified July 2016

Safety of the CO-rebreathing Method in Stable Coronary Artery Disease and COPD Patients

Conditions:   Cardiovascular Disease;   Chronic Obstructive Pulmonary Disease
Intervention:  
Sponsor:   Norwegian University of Science and Technology
Completed - verified July 2016

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Recruiting - verified July 2016

Impact of IntraVascular UltraSound Guidance on Outcomes of Xience Prime Stents in Long Lesions (IVUS-XPL Study)

Condition:   Coronary Artery Disease
Interventions:   Procedure: PCI with IVUS guidance;   Procedure: PCI without IVUS guidance
Sponsor:   Yonsei University
Completed - verified July 2016

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Conditions:   Heart; Dysfunction Postoperative, Cardiac Surgery;   Genetic Predisposition to Disease;   Atrial Fibrillation;   Myocardial Infarction;   Heart Failure
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   Texas Heart Institute;   University of Texas Southwestern Medical Center
Recruiting - verified July 2016

Post Ten Year Follow up Assessment of a Phase I Trial of Angiogenic Gene Therapy

Conditions:   Coronary Artery Disease;   Ischemia
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   Stony Brook University
Completed - verified July 2016

Effects of Amino Acids on Regional Lipid Metabolism

Condition:   Hypertriglyceridemia
Interventions:   Dietary Supplement: Amino acids;   Dietary Supplement: Placebo
Sponsors:   University of Arkansas;   National Institute on Aging (NIA)
Recruiting - verified July 2016

IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)

Conditions:   Heart Failure;   Coronary Artery Disease;   Ischemic Cardiomyopathy;   Non-ischemic Cardiomyopathy
Interventions:   Other: Advanced cardiac imaging;   Other: Standard Cardiac Imaging
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR);   The Finnish Funding Agency for Technology and Innovation (TEKES)
Recruiting - verified July 2016

Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI)

Condition:   Coronary Artery Disease
Intervention:   Other: Myocardial perfusion imaging using Rb-82 PET or Tc-99m or Tl SPECT
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified July 2016

A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease

Condition:   Cardiovascular Disease
Interventions:   Drug: Dalcetrapib;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Terminated - verified July 2016

Clinical Trial for Dose Finding and Safety of RVX000222 in Subjects With Stable Coronary Artery Disease

Conditions:   Atherosclerosis;   Coronary Artery Disease
Interventions:   Drug: RVX000222;   Drug: Placebo
Sponsor:   Resverlogix Corp
Completed - verified July 2016

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified July 2016

IK-1001 (Sodium Sulfide (Na2S) for Injection) in Subjects With Acute ST-Segment Elevation Myocardial Infarction

Condition:   ST-Segment Elevation Myocardial Infraction
Interventions:   Drug: Sodium Sulfide (Na2S) for Injection;   Drug: Placebo
Sponsor:   Mallinckrodt
Withdrawn - verified July 2016

The SMARTEX Heart Failure Study

Condition:   Heart Failure
Interventions:   Behavioral: Aerobic Interval Training;   Behavioral: Moderate continues training;   Behavioral: Recommendation of regular moderate exercise
Sponsors:   Norwegian University of Science and Technology;   University Hospital, Antwerp;   UMC Utrecht;   Technische Universität München;   Heartcenter Leipzig GmbH;   Bispebjerg Hospital;   St. Olavs Hospital;   Helse Stavanger HF
Completed - verified July 2016

Associations Between Diabetes Care and Haptoglobin Genotype On outComes

Conditions:   Diabetes;   Cardiovascular Disease;   Myocardial Infarction;   Stroke
Intervention:  
Sponsor:   Clalit Health Services
Active, not recruiting - verified July 2016

Cardiac FDG PET Viability Registry

Conditions:   Heart Failure;   Ischemic Heart Disease;   Myocardial Dysfunction
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Ontario Ministry of Health and Long Term Care
Recruiting - verified July 2016

Safety, Pharmacokinetic Study of RVX000222 in Healthy Subjects and Subjects With Low HDL Cholesterol

Conditions:   Dyslipidemia;   Atherosclerosis;   Acute Coronary Syndrome;   Cardiovascular Disease
Interventions:   Drug: RVX000222;   Drug: Placebo
Sponsor:   Resverlogix Corp
Completed - verified July 2016

Study to Assess the Tolerability and Efficacy of Anacetrapib in Patients With Coronary Heart Disease (CHD) or CHD Risk-Equivalent Disease (MK-0859-019)

Conditions:   Coronary Heart Disease (CHD);   CHD Risk-Equivalent Disease
Interventions:   Drug: anacetrapib;   Drug: Comparator: placebo
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified July 2016

Abrupt Versus Tapered Interruption of Chronic Clopidogrel Therapy After DES Implantation

Condition:   Coronary Artery Disease
Interventions:   Drug: Abrupt Clopidogrel Interruption;   Drug: Clopidogrel Tapering
Sponsor:   Deutsches Herzzentrum Muenchen
Terminated - verified June 2012

The Melatonin Adjunct in the Acute myocaRdial Infarction Treated With Angioplasty

Condition:   Acute Myocardial Infarction
Intervention:   Drug: melatonin
Sponsor:   Alberto Domínguez Rodríguez
Terminated - verified July 2016

Factors Associated With Coronary Heart Disease in African Americans in the Jackson Heart Study

Conditions:   Cardiovascular Diseases;   Coronary Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified December 2006

A Long Term Extension of Study NC19453 Evaluating Safety and Efficacy of RO4607381

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib (RO4607381);   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified July 2016

PET and Recovery Following Revascularization (PARR 2)

Conditions:   Coronary Artery Disease;   Ventricular Dysfunction, Left
Interventions:   Procedure: Positron emission tomography: FDG viability imaging;   Other: PET imaging
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR);   Heart and Stroke Foundation of Ontario
Completed - verified July 2016

Cardiology Biobank Registry

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   Emory University
Recruiting - verified July 2016

Randomized Controlled Trial of Health Care to Elderly Patients.

Conditions:   Congestive Heart Failure;   Angina Pectoris;   Asthma;   Pneumonia;   Fractures
Interventions:   Other: Multicomponent treatment;   Other: usual care
Sponsors:   Norwegian University of Science and Technology;   Central Norway Regional Health Authority
Completed - verified July 2016

Effect of Increased Oxygenation in the Air During Endurance Training in Stable Angina Pectoris Patients

Condition:   Angina Pectoris
Interventions:   Behavioral: Hypoxic interval training;   Behavioral: Normoxic interval training
Sponsors:   Norwegian University of Science and Technology;   Aarhus University Hospital
Completed - verified July 2016

Estrogen Replacement to Reduce Risk of Neurologic Injury After Coronary Artery Bypass Graft Surgery

Conditions:   Coronary Disease;   Cardiovascular Diseases;   Heart Diseases;   Neurologic Manifestations
Interventions:   Drug: Estrogen Replacement Therapy;   Procedure: Surgery
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Terminated - verified December 2007

Effect of Exercise on Elevated C-reactive Protein Concentrations in Formerly Inactive Adults

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Obesity
Intervention:   Procedure: Exercise
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified December 2007

Logical Analysis of Data and Cardiac Surgery Risk

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Aortic Valve Stenosis;   Mitral Valve Stenosis
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

Estrogen Receptor Variants, HDL, and Atherosclerosis

Conditions:   Cardiovascular Diseases;   Atherosclerosis;   Coronary Arteriosclerosis;   Heart Diseases
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

MRI Derived Organ & Tissue Mass Changes With Weight Loss - Ancillary to Look AHEAD

Conditions:   Cardiovascular Diseases;   Atherosclerosis;   Obesity;   Diabetes Mellitus, Non-insulin Dependent;   Heart Diseases;   Myocardial Infarction;   Diabetes Mellitus
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

Heavy Metals, Obesity and Cardiovascular Risk - Ancillary to Look AHEAD

Conditions:   Diabetes Mellitus, Non-insulin Dependent;   Cardiovascular Diseases;   Obesity;   Myocardial Infarction;   Heart Diseases;   Diabetes Mellitus
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Failure, Congestive;   Heart Diseases
Interventions:   Procedure: CABG surgery plus MED;   Drug: Active Medication Alone;   Procedure: CABG plus MED and SVR
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified July 2016

Genetics of Coronary Artery Disease in Alaskan Natives (GOCADAN)

Conditions:   Heart Diseases;   Cardiovascular Diseases;   Atherosclerosis;   Hypertension;   Diabetes Mellitus;   Coronary Arteriosclerosis
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified May 2009

Genetic Epidemiology of Coronary Heart Disease

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

Multi-Ethnic Study of Atherosclerosis (MESA)

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Coronary Artery Disease;   Coronary Disease;   Stroke;   Myocardial Infarction;   Heart Failure;   Diabetes Mellitus, Type 2;   Hypertension;   Diabetes Mellitus
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified April 2012

Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Carotid Artery Diseases;   Coronary Disease;   Polycystic Ovary Syndrome
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

Worcester Heart Attack Community Surveillance Study

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Myocardial Infarction
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified May 2009

Whitehall II - Social and Occupational Influences On Health and Illness

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Myocardial Ischemia;   Hypertension
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

Strong Heart Study

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Atherosclerosis;   Asthma;   Carotid Artery Diseases;   Coronary Disease;   Hypercholesterolemia;   Hypertension;   Diabetes Mellitus;   Obesity
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified May 2009

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Diabetes Mellitus;   Heart Diseases;   Hypercholesterolemia;   Hypertension;   Myocardial Infarction;   Myocardial Ischemia;   Heart Failure
Interventions:   Drug: Inhibitors, ACE;   Drug: amlodipine;   Drug: lisinopril;   Drug: doxazosin;   Drug: chlorthalidone;   Drug: pravastatin;   Behavioral: diet, fat-restricted
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2009

Effects of Endotoxin in Normal Human Volunteers

Conditions:   Healthy;   Lung Disease;   Sepsis;   Septic Shock
Interventions:   Drug: Reference Endotoxin;   Drug: Inhaled Nitric Oxide
Sponsor:   National Institutes of Health Clinical Center (CC)
Completed - verified July 2016