Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging

Condition:   Coronary Artery Disease (CAD)
Interventions:   Procedure: Optical Coherence Tomography (OCT);   Procedure: Intravascular Ultrasound (IVUS)
Sponsor:   Columbia University
Recruiting - verified December 2016

The Usefulness of Coronary CT Scan After Everolimus-eluting Bioabsorbable Scaffold Implantation for Coronary Artery Disease

Condition:   Coronary Disease
Intervention:   Procedure: Computed tomographic scan
Sponsors:   Jung-min Ahn;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified November 2016

Myocardial Ischemia and Transfusion

Conditions:   Myocardial Infarction;   Anemia
Intervention:   Biological: Red Blood Cell Transfusion
Sponsors:   Rutgers, The State University of New Jersey;   University of Pittsburgh;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified December 2016

Trans Radial Versus Transfemoral Route for Coronary Angiography

Condition:   Coronary Artery Disease
Interventions:   Procedure: transradial;   Procedure: Transfemoral
Sponsor:   Sheri Kashmir Institute of Medical Sciences
Completed - verified December 2016

Epicardial Fat Pads Ablation During Coronary Surgery

Conditions:   Atrial Fibrillation;   Ischemic Heart Disease
Interventions:   Procedure: Coronary artery bypass grafting;   Procedure: Epicardial ganglionated plexi ablation;   Procedure: implantable loop recorder
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified December 2016

The New Pharmaceutical Composition Containing Botulinum Toxin to Treat Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Ischemic Heart Disease
Interventions:   Drug: Pharmaceutical composition containing botulinum toxin;   Drug: 0.9% normal saline;   Procedure: Coronary artery bypass grafting
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified December 2016

Evaluation of Coronary Artery Plaque Volume Progression/Regression and Safety of Alirocumab in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia

Conditions:   Hypercholesterolemia;   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553;   Drug: atorvastatin;   Drug: rosuvastatin;   Drug: fenofibrate;   Drug: bezafibrate;   Drug: ezetimibe;   Drug: antiplatelets;   Drug: anticoagulants
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified November 2016

INTegrated Assessment of intERmediate Coronary Stenoses by Fractional Flow rEserve (FFR) and Near-infraREd Spectroscopy (NIRS)

Condition:   Borderline Coronary Stenoses Assessment, Fractional Flow Reserve, Plaque Composition
Intervention:   Device: FFR and IVUS-NIRS
Sponsors:   S.M. Misericordia Hospital;   San Giovanni Addolorata Hospital
Recruiting - verified December 2016

Quantitative Coronary Angiography Versus Intravascular Ultrasound GUIDancE for Drug-Eluting Stent Implantation

Conditions:   Coronary Disease;   Coronary Stenoses
Interventions:   Device: quantitative coronary angiography guided coronary intervention with everolimus-eluting stent or zotarolimus-eluting stent;   Device: intravascular ultrasound guided coronary intervention with everolimus-eluting stent or zotarolimus-eluting stent
Sponsors:   CHEOL WHAN LEE, M.D., Ph.D;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified November 2016

Heartflow (AFFECTS)

Condition:   Cardiovascular Abnormalities
Intervention:   Procedure: FFRct and SPECT
Sponsor:   Baylor Research Institute
Recruiting - verified November 2016

The IDEAL-PCI Extended Registry

Conditions:   Coronary Arterioscleroses;   Platelet Dysfunction Due to Drugs
Interventions:   Drug: DAPT reduction;   Drug: DAPT on-target;   Drug: DAPT intensification
Sponsor:   Kaiser Franz Josef Hospital
Recruiting - verified November 2016

Education Model for Cardiac Patients

Conditions:   Coronary Artery Disease;   Coronary Disease;   Arteriosclerosis;   Cardiovascular Diseases
Interventions:   Behavioral: educational model + follow up;   Behavioral: usual care
Sponsor:   University of Sao Paulo
Not yet recruiting - verified November 2016

Metabolomic Profile of Patients Undergoing Myocardial Perfusion SPECT

Condition:   Ischemic Heart Disease
Intervention:   Other: Non intervention
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Recruiting - verified December 2016

Tracking Endothelial Cells in Arterial Injury

Conditions:   Endothelial Progenitor Cells;   Coronary Artery Disease;   Vascular Injury;   Coronary Angiography
Intervention:   Biological: Administration of radio labelled endothelial outgrowth cells
Sponsors:   University of Edinburgh;   British Heart Foundation
Recruiting - verified October 2016

Lp(a) and Aortic Valve Calcification

Condition:   Heterozygous Familial Hypercholesterolemia
Sponsors:   Laval University;   Amgen
Not yet recruiting - verified December 2016

Registry of Malignant Arrhythmias and Sudden Cardiac Death - Influence of Diagnostics and Interventions

Conditions:   Ventricular Tachycardia;   Ventricular Fibrillation;   Sudden Cardiac Death;   Coronary Angiography;   Electrophysiologic Testing (EP);   Catheter Ablation;   Percutaneous Coronary Intervention (PCI);   Internal Cardioverter Defibrillator (ICD)
Sponsor:   Universitätsmedizin Mannheim
Recruiting - verified November 2016

Preventive Heart Rehabilitation to Prevent Complications in Patients Undergoing Elective Open Heart Surgery

Conditions:   Coronary (Artery); Disease;   Aortic Valve Stenosis;   Cardiac Surgery
Interventions:   Behavioral: Pre+post-operative Cardiac rehabilitation;   Behavioral: Postoperative Cardiac rehabilitation
Sponsor:   University Medical Center Groningen
Not yet recruiting - verified December 2016

Randomized Comparison of Cangrelor, Tirofiban and Prasugrel in Patients With STEMI Referred for Primary PCI.

Conditions:   Coronary Artery Disease;   STEMI - ST Elevation Myocardial Infarction
Interventions:   Drug: Cangrelor;   Drug: Tirofiban;   Drug: Prasugrel
Sponsor:   University Hospital Inselspital, Berne
Not yet recruiting - verified November 2016

Trial of MiStent Compared to Xience in Japan

Condition:   Coronary (Artery); Disease
Interventions:   Device: MiStent (MT005) Coronary Artery Stent;   Device: Xience Coronary Artery Stent
Sponsors:   Micell Technologies;   Cardialysis BV;   ClinLogix. LLC
Recruiting - verified November 2016

Diagnostic Accuracy of On-line Quantitative Flow Ratio

Condition:   Coronary Artery Disease
Intervention:   Other: QFR (observational)
Sponsor:   Aarhus University Hospital Skejby
Recruiting - verified November 2016

Clinical Outcomes and Efficacy of Left Ventricular Assist Device for Korean Patients With Cardiogenic Shock

Condition:   Shock, Cardiogenic
Sponsor:   Jeong Hoon Yang
Recruiting - verified December 2016

High-Sensitivity Cardiac Troponin T to OPtimize Chest Pain Risk Stratification

Conditions:   Acute Coronary Syndrome;   Chest Pain
Interventions:   Procedure: Blood Sample;   Behavioral: HEART Score
Sponsors:   University of Florida;   Roche Diagnostics Corporation
Not yet recruiting - verified December 2016

One-hour Troponin in a Low-prevalence Population of Acute Coronary Syndrome

Conditions:   Non-ST Elevation Myocardial Infarction;   Acute Coronary Syndrome;   Angina, Unstable;   NSTEMI - Non-ST Segment Elevation MI
Intervention:   Procedure: 1-hour hs-cTnT
Sponsors:   Oslo University Hospital;   University of Oslo
Recruiting - verified December 2016

The Accuracy of the Mini RELF Device for the Diagnosis of an Acute Coronary Artery Occlusion.

Conditions:   Chest Pain;   ST Elevation Myocardial Infarction
Intervention:   Device: Diagnostic accuracy of Mini Relf Device
Sponsor:   University Ghent
Recruiting - verified December 2016

Italian Multi-center Registry of Self-apposing Coronary Stent in Patients With STEMI

Condition:   ST Segment Elevation Myocardial Infarction
Intervention:   Device: STENTYS Xposition S
Sponsor:   UOSD Emodinamica Diagnostica e Interventistica
Recruiting - verified November 2016

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY 1142524 in Patients After Acute Myocardial Infarction With Left-ventricular Dysfunction

Condition:   Myocardial Infarction
Interventions:   Drug: BAY1142524;   Drug: Placebo
Sponsor:   Bayer
Not yet recruiting - verified October 2016

The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III

Conditions:   Cardiac Arrest;   Renal Failure;   Respiration Failure;   Myocardial Infarction;   Severe Sepsis
Intervention:   Device: Automatic RR Measurement
Sponsor:   Philips Healthcare
Recruiting - verified November 2016

Effect of DLBS1033 After Primary PCI in Patients With STE-ACS

Condition:   ST Elevation Myocardial Infarction
Interventions:   Drug: DLBS1033;   Drug: Placebo;   Drug: Standard therapy
Sponsors:   Dexa Medica Group;   Binawaluya Cardiac Hospital, Jakarta
Recruiting - verified November 2016

Diffusion MRI in Heart Failure

Conditions:   Heart Failure;   Myocardial Infarction;   Left Ventricular Hypertrophy
Intervention:   Device: Diffusion Tensor MRI (DTI)
Sponsor:   Massachusetts General Hospital
Not yet recruiting - verified November 2016

Use of Different Diagnostic Coronary Catheters Over the Radial Access - the UDDC - Radial Trial

Condition:   Stable Coronary Heart Disease
Interventions:   Device: One-catheter concept;   Device: Standard catheter
Sponsor:   Charite University, Berlin, Germany
Active, not recruiting - verified November 2016

Erythropoietin Effect on ischemic_ Reperfusion Injury in Cronary Artery Bypass Graft Surgery

Condition:   Myocardial Ischemic Reperfusion Injury
Interventions:   Drug: normal saline;   Drug: erythropoietin
Sponsors:   Shahid Beheshti University of Medical Sciences;   Pooyesh Darou
Enrolling by invitation - verified December 2016

Early Versus Late Sustained Low Efficiency Dialysis in Critically Ill Cirrhotics With Septic Shock and Acute Kidney Injury

Condition:   Cirrhotics With Septic Shock and Acute Kidney Injury
Interventions:   Biological: Early SLED;   Biological: Late SLED
Sponsor:   Institute of Liver and Biliary Sciences, India
Recruiting - verified October 2016

Comprehensive Treatment of Angina in Women With Microvascular Dysfunction

Conditions:   Angina Pectoris;   Coronary Microvascular Disease
Interventions:   Dietary Supplement: Diet;   Behavioral: Training;   Drug: Medication (with statin and ACE-inhibition)
Sponsors:   Bispebjerg Hospital;   University Hospital Bispebjerg and Frederiksberg;   Cambridge Weight Plan Limited
Not yet recruiting - verified November 2016

Detection no Invasive of a Silent Myocardial Ischemia

Conditions:   Silent Myocardial Ischemia;   Type 2 Diabetes
Intervention:   Device: echography
Sponsor:   University Hospital, Strasbourg, France
Recruiting - verified December 2016

Effect of Propofol on Cardioprotective Role of Remote Ischemic Preconditioning (RIPC)

Condition:   Myocardial Infarction
Interventions:   Other: Control;   Drug: Propofol;   Drug: Sevoflurane
Sponsor:   Seoul National University Hospital
Recruiting - verified December 2016

Bivalirudin in Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Bivalirudin;   Drug: heparin
Sponsor:   Shenzhen Salubris Pharmaceuticals Co., Ltd.
Recruiting - verified November 2016

Intravascular Ultrasound Prediction of Myocardial Size and Coronary Computed Tomography-Derived Ischemic Burden for Coronary Lesion

Condition:   Coronary Artery Disease
Intervention:   Other: Intravascular Ultrasound, coronary computed tomography angiography
Sponsors:   Asan Medical Center;   Boston Scientific Corporation
Recruiting - verified November 2016

The Box: Using Smart Technology to Improve One-year Outcome of Myocardial Infarction Patients

Condition:   Myocardial Infarction
Intervention:   Other: The Box
Sponsor:   Leiden University Medical Center
Recruiting - verified November 2016

Machine leArning Based CT angiograpHy derIved FFR: a Multi-ceNtEr, Registry

Conditions:   Coronary Heart Disease;   Coronary Artery Disease
Sponsors:   Erasmus Medical Center;   Asan Medical Center;   University Hospital, Linkoeping;   Institute of Cardiology, Warsaw, Poland;   Medical University of South Carolina;   Siemens Healthcare Diagnostics Inc
Active, not recruiting - verified November 2016

Assessment of Coronary Artery Lesion Using Optical Coherence Tomography Versus IntraVascular Ultrasound for BiorEsorbable Vascular Scaffold Implantation

Condition:   Coronary Artery Disease
Interventions:   Other: Optical coherent tomography;   Other: IntraVascular UltraSound
Sponsors:   Young-Hak Kim, MD, PhD;   Abbott Vascular
Recruiting - verified November 2016

Study on the Effect of Influenza Vaccination After Heart Attack on Future Cardiovascular Prognosis

Conditions:   Myocardial Infarction;   Influenza, Human;   Influenza Vaccines;   Heart Failure;   Stroke
Interventions:   Biological: Influenza vaccine;   Biological: Placebo
Sponsors:   Ole Frobert, MD, PhD;   Swedish Heart Lung Foundation;   Sanofi Pasteur, a Sanofi Company;   Uppsala University;   Lytics
Recruiting - verified November 2016

Interest of CARE Rule to Exclude the Hypothesis of an Acute Coronary Syndrome Without Bioassay - ICARE

Condition:   Chest Pain
Intervention:   Other: CARE Rule
Sponsor:   University Hospital, Angers
Recruiting - verified June 2016

The Impact of Post Stenting Balloon Dilatation on Coronary Microcirculation in STEMI Patients Undergoing PPCI

Condition:   ST-elevation Myocardial Infarction (STEMI)
Sponsors:   Basildon and Thurrock University Hospitals NHS Foundation Trust;   Anglia Ruskin University
Recruiting - verified December 2016

Cytokine Clearance With Cytoabsorbant Device During Cardiac Bypass

Conditions:   Myocardial Ischemia;   Heart Valve Diseases
Intervention:   Device: Cytosorb
Sponsor:   Centre Hospitalier Universitaire Vaudois
Recruiting - verified December 2016

Impact of Allo- and Autoantibodies on Chronic Cardiac Allograft Function

Conditions:   Pediatric Heart Transplantation;   Pediatric Heart Transplant Recipients
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Clinical Trials in Organ Transplantation in Children
Active, not recruiting - verified November 2016

Paced Electrocardiogram Requiring Fast Emergent Coronary Therapy (PERFECT) Study

Condition:   Acute Myocardial Infarction
Sponsor:   Hennepin County Medical Center, Minneapolis
Recruiting - verified November 2016

Ultrapower; a Minimally Invasive Tool for Evaluation of Total Cardiac Power

Condition:   Cardiac Diseases
Intervention:   Other: Comparison cardiac power and cardiac power output at different time points in the perioperative period
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital
Recruiting - verified November 2016

A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL_112;   Other: Placebo
Sponsor:   CSL Behring
Recruiting - verified December 2016

EXpanded CELL ENdocardiac Transplantation (EXCELLENT)

Condition:   Acute Myocardial Infarction
Interventions:   Drug: PROTHERACYTES;   Device: Standard of Care (Percutaneous Transluminal Coronary Angioplasty and stent(s) implantation)
Sponsor:   CellProthera
Recruiting - verified October 2016

The Physiological Impact of CTO PCI on Coronary Pressure Measurements and Correlation in Donor Vessel

Conditions:   Acute Coronary Syndrome;   Coronary Artery Disease
Sponsor:   Basildon and Thurrock University Hospitals NHS Foundation Trust
Recruiting - verified December 2016

Pilot Clinical Study of MeRes100 Sirolimus Eluting Bioresorbable Vascular Scaffold System

Condition:   Coronary Artery Disease
Intervention:   Device: MeRes100 Sirolimus Eluting Bioresorbable Vascular Scaffold System
Sponsor:   Meril Life Sciences Pvt. Ltd.
Recruiting - verified November 2016

Clinical Performance Evaluation of AQT90 FLEX TnI and TnT

Condition:   Myocardial Infarction
Sponsor:   Radiometer Medical ApS
Recruiting - verified November 2016

Assessment of Catheter-based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement

Condition:   Coronary Artery Disease
Interventions:   Device: RXi System;   Device: Pressure Wire
Sponsor:   Acist Medical Systems
Active, not recruiting - verified October 2016

Improving Quality by Maintaining Accurate Problems in the EHR

Conditions:   Asthma;   Atrial Fibrillation;   Chronic Obstructive Pulmonary Disease;   Coronary Artery Disease;   Congestive Heart Failure;   Hyperlipidemia;   Hypertension;   Myocardial Infarction;   Sickle Cell Disease;   Sleep Apnea;   Smoking;   Stroke;   Tuberculosis
Intervention:   Other: Problem List Suggestion
Sponsors:   Brigham and Women's Hospital;   Geisinger Clinic;   Oregon Health and Science University;   Vanderbilt University
Active, not recruiting - verified December 2016

Atorvastatin Effectiveness and Safety in Cardiology Patients in Real World Setting

Condition:   Coronary Artery Disease, Hypercholesterolemia, Hypertension
Intervention:   Other: No intervention
Sponsor:   Pfizer
Recruiting - verified November 2016

Attentional Capacity and Working Memory in Coronary Artery Disease Patients: Impact of the Presence of a Sleep Apnea Syndrome and Chronic Effects of Treatment With CPAP

Conditions:   Obstructive Sleep Apnea;   Acute Coronary Syndrome
Intervention:   Device: CPAP treatment
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting - verified December 2016

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified December 2016

Antiplatelet Therapy in Acute Coronary Syndrome(ACS). Safety and Efficacy of Switching Antiplatelet

Condition:   Acute Coronary Syndrome
Sponsor:   Fundación Pública Andaluza Progreso y Salud
Recruiting - verified December 2016

Impact of the Obstructive Sleep Apnea Syndrome (OSAS) on the Ventricular Remodeling After Acute Myocardial Infarction

Condition:   Recent Acute Myocardial Infarction
Interventions:   Other: Without Obstructive Sleep Apnea (syndrome);   Other: Mild or moderate Obstructive Sleep Apnea (syndrome);   Other: Severe Obstructive Sleep Apnea (syndrome);   Device: CPAP
Sponsor:   University Hospital, Montpellier
Recruiting - verified November 2016

Effects of Linagliptin on Endothelial Function

Conditions:   Type 2 Diabetes;   Coronary Artery Disease
Interventions:   Drug: Linagliptin;   Drug: Placebo
Sponsor:   Medical University of Graz
Active, not recruiting - verified November 2016

Revascularization With BVS or CABG in Patients With Advanced CAD

Condition:   Multivessel Coronary Artery Disease
Interventions:   Procedure: PCI -BVS;   Procedure: CABG
Sponsor:   Poznan University of Medical Sciences
Terminated - verified November 2016

Changes in Ischemia and Angina Over 1 Year Among ISCHEMIA Trial Screen Failures With no Obstructive CAD on Coronary CT Angiography

Conditions:   Microvascular Angina;   Angina Pectoris
Interventions:   Other: Quality of Life assessment;   Procedure: Stress imaging
Sponsors:   New York University School of Medicine;   Duke Clinical Research Institute;   Massachusetts General Hospital
Recruiting - verified December 2016

Evaluation of Myocardial Perfusion Heterogeneity Imaging in Diabetes Patients (EVADIAB)

Condition:   Type 2 Diabetes
Intervention:   Device: MPHI
Sponsor:   University Hospital, Grenoble
Completed - verified May 2015

Effect of Cilostazol on Coronary Artery Stenosis and Plaque Characteristics in Patients With T2DM

Condition:   Coronary Artery Disease
Interventions:   Drug: Cilostazol;   Drug: Aspirin
Sponsor:   Seoul National University Bundang Hospital
Completed - verified November 2016

Removal of Cytokines During Extracorporeal Circulation in Cardiac Surgery

Conditions:   Coronary Artery Disease;   Heart Valve Diseases
Intervention:   Device: CytoSorb device
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Active, not recruiting - verified September 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified December 2016

Decisional Quality for Patients With Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Behavioral: Decision Aid;   Behavioral: CAD Education
Sponsors:   University of California, San Francisco;   University of Missouri, Kansas City;   Mid America Heart Institute;   Emory University;   Massachusetts General Hospital
Enrolling by invitation - verified December 2016

TEAMS (Troponin Elevation After Major Surgery) Study

Conditions:   Perioperative Myocardial Infarction;   Disability
Sponsor:   University Health Network, Toronto
Completed - verified November 2015

Omega-3 Fatty Acids Supplementation and Atherothrombotic Biomarkers in Type 2 Diabetes and Cardiovascular Disease.

Conditions:   Type 2 Diabetes;   Cardiovascular Diseases
Intervention:   Dietary Supplement: Omega-3 PUFA
Sponsors:   Jagiellonian University;   National Science Centre, Poland
Completed - verified November 2016

Evaluating the Effects of EECP on Circulation, Blood Glucose Level and Blood Pressure in Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Sponsor:   David Grant U.S. Air Force Medical Center
Withdrawn - verified December 2016

Essential Hypotension and Adaptability Registry

Conditions:   Blood Pressure;   Depression;   Panic Attack;   Fibromyalgia;   POTS;   Inappropriate Sinus Tachycardia;   Coronary Heart Disease;   Acute Coronary Syndrome (ACS);   Acute Myocardial Infarction (AMI);   Cerebrovascular Disease (CVD);   Transient Ischemic Attack (TIA);   Atrial Fibrillation;   Diabetes Mellitus;   Cancer;   Systolic Heart Failure;   Diastolic Heart Failure;   Chronic Fatigue Syndrome;   Syncope;   Vasovagal Syncope
Sponsor:   CES University
Recruiting - verified November 2016

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Ticagrelor 60 mg;   Drug: Ticagrelor placebo
Sponsor:   AstraZeneca
Active, not recruiting - verified November 2016

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified November 2016

Screening for Abdominal Aortic Aneurysm Using a Portable Transthoracic Echocardiography Among Patients With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Sponsor:   HaEmek Medical Center, Israel
Completed - verified December 2016

Randomized Endo-Vein Graft Prospective

Condition:   Coronary Artery Bypass Grafting
Intervention:   Procedure: Vein Harvesting Procedures
Sponsor:   VA Office of Research and Development
Recruiting - verified November 2016

MACCE in Hospitalized Patients With Community-acquired Pneumonia

Condition:   Community-acquired Pneumonia
Sponsor:   University of Roma La Sapienza
Recruiting - verified November 2016

Effect of Learning and Coping Strategies in Cardiac Rehabilitation - Group Study

Condition:   Rehabilitation
Interventions:   Behavioral: Learning and coping arm;   Other: Control arm
Sponsor:   Herning Hospital
Active, not recruiting - verified December 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: Placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified November 2016

Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) Trial

Conditions:   Aging;   CAD
Intervention:   Drug: Rapamycin
Sponsor:   Mayo Clinic
Completed - verified December 2016

Cardiovascular Inflammation Reduction Trial

Condition:   Cardiovascular Disease
Interventions:   Drug: Methotrexate;   Drug: Placebo
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified November 2016

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   New York University School of Medicine;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University
Recruiting - verified December 2016

Randomized, Open Label Trial of 6 Months Versus 12 Months DAPT After Drug-Eluting Stent in STEMI

Conditions:   Myocardial Infarction;   Cardiovascular Disease
Interventions:   Other: 6 months DAPT;   Other: 12 months DAPT
Sponsors:   Maasstad Hospital;   Medtronic
Active, not recruiting - verified December 2016

The Role Of Noninvasive 320-Row Multidetector Computer Tomography

Condition:   Coronary Artery Disease
Sponsors:   University Health Network, Toronto;   Mount Sinai Hospital, Canada
Completed - verified February 2016

FITT Exercise Counseling With Interactive Accelerometry and Physical Activity in Adolescents at Increased Risk of Early Cardiovascular Disease: A Pilot Study

Condition:   Coronary Artery Disease Risk High
Intervention:   Device: BodyMedia
Sponsor:   Boston Children’s Hospital
Active, not recruiting - verified December 2016

The Massachusetts General Hospital Optical Coherence Tomography Registry

Condition:   Coronary Artery Disease
Sponsors:   Ik-Kyung Jang, MD, PhD;   Medtronic;   Boston Scientific Corporation;   Massachusetts General Hospital
Active, not recruiting - verified November 2016

To Investigate the Role of Upstream High Dose Statin in STEMI

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Atorvastatin calcium;   Drug: Inactive Placebo
Sponsors:   The Western Pennsylvania Hospital;   West Penn Allegheny Health System
Completed - verified November 2016

CareLink® Network Evaluation

Condition:   Heart Failure
Intervention:   Other: Medtronic CareLink® Network
Sponsor:   Medtronic Bakken Research Center
Completed - verified November 2016

Study to Assess the Tolerability and Efficacy of Anacetrapib in Patients With Coronary Heart Disease (CHD) or CHD Risk-Equivalent Disease (MK-0859-019)

Conditions:   Coronary Heart Disease (CHD);   CHD Risk-Equivalent Disease
Interventions:   Drug: anacetrapib;   Drug: Comparator: placebo
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified November 2016

Prospective Observational Epidemiologic Study of Maraviroc's Safety

Condition:   Human Immunodeficiency Virus
Interventions:   Drug: Maraviroc along with an optimized background antiretroviral drug regimen;   Drug: Optimized background antiretroviral drug regimen without maraviroc
Sponsors:   ViiV Healthcare;   Pfizer
Active, not recruiting - verified December 2016

Safety and Tolerability of E5555 and Its Effects on Markers of Intravascular Inflammation in Subjects With Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Drug: E5555;   Drug: Placebo
Sponsor:   Eisai Inc.
Completed - verified November 2016

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Peripheral Artery Disease
Intervention:   Procedure: MRI
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified November 2016

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Cardiovascular Disease
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified November 2016

Bogalusa Heart Study

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Hypertension
Sponsors:   Tulane University;   National Heart, Lung, and Blood Institute (NHLBI);   National Institute on Aging (NIA);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute of Environmental Health Sciences (NIEHS)
Active, not recruiting - verified December 2016