Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Randomized Controlled Comparison Between One Versus More Than Six Months of Dual Antiplatelet Therapy After Biolimus A9-eluting Stent Implantation

Condition:   Coronary Artery Disease
Interventions:   Device: BioFreedom with 1 month DAPT;   Device: BioMatrix Flex with 6 to 12 months DAPT
Sponsor:   Yonsei University
Not yet recruiting - verified July 2015

Prevalence of Chronic Kidney Disease and Its Association With Clinical Outcome in Patients With Coronary Heart Disease

Conditions:   Coronary Heart Disease;   Chronic Kidney Disease
Intervention:  
Sponsors:   Peking University First Hospital;   Pfizer
Not yet recruiting - verified July 2015

Coronary Artery and Systemic Autoimmune Disease: Diagnostics and Treatment

Conditions:   Autoimmune Diseases;   Coronary Artery Disease
Intervention:  
Sponsors:   Semmelweis University Heart and Vascular Center;   University of Debrecen
Recruiting - verified July 2015

VEST III PMS Clinical Protocol

Condition:   Coronary Artery Disease
Interventions:   Device: VEST External Support;   Procedure: Coronary Artery Bypass Surgery
Sponsor:   Vascular Graft Solutions Ltd.
Not yet recruiting - verified July 2015

Bioresorbable Polymer ORSIRO Versus Durable Polymer RESOLUTE ONYX Stents

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina Pectoris;   Acute Coronary Syndrome;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Orsiro;   Device: Resolute Onyx
Sponsor:   Thorax Centrum Twente
Not yet recruiting - verified July 2015

Ivabradine and Post-revascularisation Microcirculatory Dysfunction

Conditions:   Coronary Artery Disease;   Angina
Intervention:   Drug: Ivabradine
Sponsor:   Liverpool Heart and Chest Hospital NHS Foundation Trust
Not yet recruiting - verified July 2015

Comparison of a CrossBoss First Versus Standard Wire Escalation Strategy for Crossing Coronary Chronic Total Occlusion: the "CrossBoss First" Trial

Conditions:   Arteriosclerosis;   Coronary Artery Disease;   Myocardial Ischemia;   Coronary Disease
Interventions:   Procedure: CrossBoss Catheter;   Procedure: Antegrade Wire Escalation Strategy
Sponsors:   North Texas Veterans Healthcare System;   Henry Ford Hospital;   Massachusetts General Hospital;   Avera Sacred Heart Hospital;   United Heart and Vascular Clinic/United Hospital;   St. Boniface General Hospital Research Centre;   Deborah Heart and Lung Center;   Sutter Health;   Edward Hospital
Not yet recruiting - verified July 2015

OCT Evaluation 3 Months After Sirolimus Eluting Stent Implantation

Condition:   Coronary Artery Disease
Interventions:   Device: Sirolimus Eluting Stent Inspiron;   Device: Bare Metal Stent
Sponsor:   Scitech Produtos Medicos Ltda
Recruiting - verified July 2015

Stavanger UncomPlicatEd Elective PCI Same DaY Discharge Study (SPEEDY Study)

Condition:   Coronary Artery Disease
Intervention:   Procedure: same day discharge
Sponsor:   Helse Stavanger HF
Not yet recruiting - verified July 2015

XIENCE PRIME SV Everolimus Eluting Coronary Stent Post Marketing Surveillance (XIENCE PRIME SV PMS)

Conditions:   Ischemic Heart Disease;   Angina Pectoris;   Coronary Artery Disease;   Coronary Artery Occlusion;   Myocardial Ischemia
Intervention:   Device: XIENCE PRIME SV Everolimus Eluting Coronary Stent
Sponsor:   Abbott Vascular
Active, not recruiting - verified July 2015

XIENCE Xpedition Everolimus-Eluting Coronary Stent Post Marketing Surveillance (XIENCE Xpedition SV PMS)

Conditions:   Ischemic Heart Disease;   Angina Pectoris;   Coronary Artery Disease;   Myocardial Ischemia
Intervention:   Device: XIENCE Xpedition 2.25 mm stent
Sponsor:   Abbott Vascular
Active, not recruiting - verified July 2015

Therapy of Preconditioned Autologous BMMSCs for Patients With Ischemic Heart Disease

Conditions:   Myocardial Infarction;   Acute Myocardial Infarction;   Ischemic Cardiomyopathy
Intervention:   Biological: BMMSCs
Sponsors:   Academy Military Medical Science, China;   Sun Yat-sen University
Not yet recruiting - verified July 2015

Pilot Study of the Fantom Bioresorbable Scaffold (FANTOM I)

Condition:   Coronary Artery Disease
Intervention:   Device: Fantom Scaffold
Sponsor:   REVA Medical, Inc.
Active, not recruiting - verified July 2015

Follow-up of Patients Bound for PCI After Implementation of a Helicopter Emergency Medical System

Condition:   ST-elevation Myocardial Infarction
Intervention:   Other: Helicopter Emergency Medical Service
Sponsors:   Rigshospitalet, Denmark;   TrygFonden, Denmark
Active, not recruiting - verified July 2015

Reverse the HYpoTHyroid Status in Acute Myocardial InfarCtion (RHYTHMIC)

Conditions:   Myocardial Infarction;   Hypothyroidism
Intervention:   Drug: Levothyroxine
Sponsors:   Cardiovascular Institute & Fuwai Hospital;   Beijing Municipal Science & Technology Commission;   Peking Union Medical College Hospital;   Peking University Third Hospital;   Beijing Anzhen Hospital;   Beijing Chao Yang Hospital;   Beijing Friendship Hospital;   The Luhe Teaching Hospital of the Capital Medical University
Not yet recruiting - verified July 2015

Tomography Emission Positron Assessment of Endothelial Dysfunction With the Waning of a Heart Attack in Patients With Diabetes Type II

Condition:   Myocardial Infarction
Intervention:   Other: Coronary endothelial function measurements by quantitative method (TEP at 15O-H2O)
Sponsor:   University Hospital, Caen
Recruiting - verified July 2015

Study of Platelet Activation by Severe Aortic Stenosis and Its Correction by Transcatheter Aortic Valve Implantation

Condition:   Aortic Stenosis
Interventions:   Other: test;   Other: control group
Sponsors:   University Hospital, Toulouse;   Medtronic
Recruiting - verified July 2015

COOL AMI EU Pilot Trial to Assess Cooling as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Device: Cooling + PCI;   Device: PCI only
Sponsor:   ZOLL Circulation, Inc., USA
Recruiting - verified July 2015

The Use of Aging Biomarkers to Predict Adverse Outcomes After Cardiac Surgery

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   HealthSpan Dx;   Duke University
Recruiting - verified July 2015

Myocardial Deformation in Real-time 3D Ultrasound. Normal Values in Adults and Validation Against the Tagged MRI

Condition:   Myocardial Infarction
Interventions:   Other: MRI;   Other: 3D cardiac ultrasound
Sponsor:   University Hospital, Caen
Recruiting - verified July 2015

Effects of Glucagon Like Peptide-1 on No-reflow

Condition:   Acute ST-segment Elevation Myocardial Infarction
Interventions:   Drug: liraglutide;   Drug: placebo
Sponsor:   Chen Wei Ren, MD
Recruiting - verified July 2015

Assessment of Prospective CYP2C19 Genotype Guided Dosing of Anti-Platelet Therapy in Percutaneous Coronary Intervention

Conditions:   Acute Coronary Syndrome;   Cardiovascular Diseases
Intervention:   Genetic: CYP2C19 genotyping
Sponsor:   University of Pennsylvania
Recruiting - verified July 2015

Novel Biomarkers of Thrombotic Risk

Condition:   Myocardial Infarction
Intervention:  
Sponsors:   University of Vermont;   Janssen Research & Development, LLC
Recruiting - verified July 2015

Colesevelam, Lipids And Sugars, South Asian Canadian Trial

Condition:   Dyslipidemia
Intervention:  
Sponsors:   Canadian Cardiovascular Research Network;   Valeant Canada Limited
Recruiting - verified July 2015

Physiotherapy Exercises in Patients With Sternal Instability After Cardiovascular Surgery

Conditions:   Mediastinitis;   Coronary Artery Disease;   Cardiovascular Infections
Intervention:   Other: physiotherapy exercises
Sponsors:   Emilia Nozawa, PT PhD;   University of Sao Paulo
Completed - verified July 2015

HYbrid CoronAry Revascularization in DiabeticS

Conditions:   Diabetes;   Heart Disease
Interventions:   Procedure: Treatment;   Procedure: Control
Sponsor:   Ottawa Heart Institute Research Corporation
Not yet recruiting - verified July 2015

Myocardial Regional Function by Dobutamine Stress Echocardiography in the Metabolic Syndrome and Type 2 Diabetes

Condition:   Diabetes-related Complications
Intervention:   Drug: dobutamine
Sponsor:   University of Avignon
Recruiting - verified July 2015

Preventive aBlation of vEntricular tachycaRdia in Patients With myocardiaL INfarction

Condition:   Ventricular Tachycardia
Intervention:   Procedure: VT ablation
Sponsor:   Biotronik SE & Co. KG
Recruiting - verified July 2015

Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCI

Conditions:   Myocardial Ischemia;   Coronary Artery Disease;   Endothelial Dysfunction
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   University Hospital of Limerick
Recruiting - verified July 2015

Evaluation of Antiplatelet Effects and Safety of Intraoperative Administration of Ticagrelor Versus Clopidogrel

Condition:   Coronary Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   Yongjian Wu
Recruiting - verified July 2015

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Not yet recruiting - verified July 2015

The Miami Heart Study at Baptist Health South Florida

Condition:   Cardiovascular Disease
Intervention:  
Sponsors:   Baptist Health South Florida;   Quest Diagnostics;   University of California, Los Angeles
Recruiting - verified July 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural Medical University ;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified July 2015

Biobehavioral Physical Therapy Strategies Based on Therapeutic Exercise Applied to Chronic Migraine Patients

Conditions:   Chronic Migraine;   Chronic Headache
Interventions:   Behavioral: Therapeutic patient education;   Other: Therapeutic exercise;   Other: No intervention;   Other: Manual Therapy
Sponsor:   Universidad Autonoma de Madrid
Not yet recruiting - verified July 2015

Acute Safety, Deliverability and Efficacy of the Medtronic Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System in the Treatment of Suitable Patients According to Indication for Use (CHINA RESOLUTE INTEGRITY STUDY)

Conditions:   Ischemic Heart Disease;   Cardiovascular Diseases;   Arteriosclerosis;   Coronary Artery Disease
Intervention:   Device: Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System
Sponsor:   Medtronic Vascular
Active, not recruiting - verified July 2015

Prospective Registry of Acute Coronary Syndromes in Ferrara

Condition:   Acute Coronary Syndromes
Intervention:   Other: prospective collection of data and follow-up
Sponsor:   University Hospital of Ferrara
Recruiting - verified July 2015

Safety and Efficacy Evaluation of Intracoronary Infusion of Allogeneic Human Cardiac Stem Cells in Patients With AMI

Condition:   Acute Myocardial Infarction
Interventions:   Other: Allogeneic human cardiac stem cells (CSCs);   Other: Human Serum Albumin-HSA 5%
Sponsors:   Coretherapix;   European Commission;   Universitaire Ziekenhuizen Leuven;   Saint-Louis Hospital, Paris, France;   Hospital General Universitario Gregorio Marañon;   Complejo Hospitalario de Navarra;   Hospital Clínico Universitario de Valladolid;   Hospital Donostia;   Hospital Clínico Universitario de Valencia;   Hospital Universitario de Salamanca;   Hospital Universitario Virgen de la Victoria
Recruiting - verified July 2015

MagicTouch Sirolimus Drug Coated Balloon Catheter for the Treatment of Coronary Lesions

Condition:   Coronary Artery Disease
Intervention:   Device: MAGIC-TOUCH Drug-eluting Balloon
Sponsor:   Scitech Produtos Medicos Ltda
Recruiting - verified July 2015

An Observational Prospective Study to Understand the Usage Pattern of Ticagrelor With ACS (Acute Coronary Syndrome)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Harvard Clinical Research Institute;   Medstar Research Institute
Recruiting - verified June 2015

Brilinta Taiwan Post Approval Safety Study

Condition:   Non ST-elevation Myocardial Infarction
Intervention:   Drug: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Sponsor:   AstraZeneca
Recruiting - verified July 2015

The Asahi Intecc PTCA Chronic Total Occlusion Study

Conditions:   Coronary Artery Disease;   Coronary Artery Chronic Total Occlusion
Intervention:   Device: Revascularization of Coronary Artery Chronic Total Occlusion (Corsair, Gaia, Asahi Guide Wires)
Sponsors:   Asahi Intecc USA Inc;   Medpace, Inc.
Recruiting - verified July 2015

Clinical Trial of the cAd3-EBO and cAd3-EBOZ Ebola Vaccines in Healthy Adults in Uganda

Condition:   Hemorrhagic Fever, Ebola
Interventions:   Biological: cAd3-EBOZ;   Biological: cAd3-EBO
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   US Military HIV Research Program;   The EMMES Corporation
Active, not recruiting - verified February 2015

Clinical Study Protocol - Debris Interventional Removal in ACS (DESIRE-ACS)

Conditions:   Coronary Disease;   Acute Coronary Syndrome;   Coronary Occlusion
Intervention:   Device: Bell Balloon Catheter
Sponsor:   Angioslide Ltd.
Recruiting - verified July 2015

The Preventive Implantation of Bioresorbable Vascular Scaffold on Functionally Insignificant Stenosis With Vulnerable Plaque Characteristics

Conditions:   Coronary Artery Disease;   Plaque, Atherosclerotic
Interventions:   Device: Bioresorbable Vascular Scaffold;   Drug: Optimal Medical treatment
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2015

Combined Coronary and Cerebral Angiography and Intervention for Coronary and Cerebrovascular Atherosclerosis

Conditions:   Coronary Stenosis;   Cerebral Stenosis
Interventions:   Other: simultaneous coronary and cerebral intervention;   Other: staged coronary and cerebral intervention
Sponsor:   Capital Medical University
Recruiting - verified July 2015

A High-Resolution Magnetic Resonance Imaging Study to Evaluate the Effect of Rosuvastatin on Carotid Atherosclerotic Plaques

Conditions:   Arteriosclerosis;   Diabetes Mellitus;   Lipid Disorder
Interventions:   Drug: Rosuvastatin 5mg;   Drug: Rosuvastatin 20mg
Sponsor:   Capital Medical University
Recruiting - verified July 2015

CCC Project- Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   Beijing Institute of Heart, Lung and Blood Vessel Diseases;   American Heart Association;   Chinese Society of Cardiology
Recruiting - verified July 2015

Long-term Follow-up of antithrombotIc Management Patterns in Acute Coronary Syndrome Patients in Asia-China Extension

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified July 2015

Assessment of Coronary Flow Reserve by PET-H215O and FFR. Comparison With Dynamic Acquisition Using CZT Camera

Condition:   Coronary Artery Disease
Intervention:   Other: ASSESSMENT OF CORONARY FLOW RESERVE BY PET-H215O AND FFR
Sponsors:   University Hospital, Caen;   Spectrum Dynamics
Recruiting - verified July 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

A Clinical Trial on the Candidate Vaccine cAd3-EBOZ in Healthy Adults in Switzerland

Condition:   Ebola Vaccines
Intervention:   Biological: cAd3-EBOZ
Sponsors:   Centre Hospitalier Universitaire Vaudois;   Infectious Disease Service, CHUV, Lausanne;   Policlinique Médicale Universitaire;   Clinical Trial Unit, Lausanne University Hospital;   Swiss Tropical & Public Health Institute;   University of Lausanne;   GlaxoSmithKline;   World Health Organization;   Immunology and Allergy Service, CHUV, Lausanne
Completed - verified July 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified July 2015

3D-Printed CPAP Masks for Children With Obstructive Sleep Apnea

Conditions:   Sleep Apnea, Obstructive;   Craniofacial Abnormalities;   Pediatric Disorder
Intervention:   Device: Personalized continuous positive airway pressure (CPAP) mask
Sponsors:   Robert J. Morrison, MD;   American Academy of Otolaryngology-Head and Neck Surgery Foundation;   University of Michigan
Recruiting - verified July 2015

PLATINUM Diversity

Conditions:   Atherosclerosis;   Coronary Artery Disease
Intervention:   Device: Percutaneous coronary intervention (Promus PREMIER)
Sponsor:   Boston Scientific Corporation
Recruiting - verified July 2015

A Pilot Study of Transcoronary Myocardial Cooling

Condition:   Acute Myocardial Infarction
Interventions:   Other: Cohort A - Room temperature coronary perfusate;   Other: Cohort B - Cooled coronary perfusate
Sponsor:   Royal Brompton & Harefield NHS Foundation Trust
Completed - verified July 2015

PARACHUTE China Approval Trial

Condition:   Ischemic Heart Failure
Intervention:   Device: Parachute Implant
Sponsors:   CardioKinetix, Inc;   Guangzhou Chuangsi Medical Technology Co., Ltd.;   Peking University
Active, not recruiting - verified July 2015

Exercise as a Life-long Medicine in Patients With Coronary Artery Disease

Conditions:   Cardiovascular Diseases;   Myocardial Infarction;   Angina (Stable)
Interventions:   Behavioral: high-intensity exercise training;   Behavioral: web-based follow-up program;   Behavioral: usual care
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital;   Levanger Hospital
Recruiting - verified July 2015

Left vs Right Radial Approach in the Setting of Primary Percutaneous Coronary Intervention for ST-elevation Myocardial Infarction

Condition:   Transradial Approach, Primary PCI, ST-segment Elevation Myocardial Infarction
Interventions:   Procedure: Left radial approach;   Procedure: Right radial approach
Sponsor:   Capital Medical University
Completed - verified September 2014

DES Versus BiOSS LIM - POLBOS II Study

Condition:   Coronary Artery Disease
Interventions:   Procedure: Coronary angioplasty with stent implantation;   Drug: Dual antipletlet therapy (DAPT)
Sponsor:   Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Completed - verified July 2015

the Effect Between Platelet Reactivation and Antiplatelet Drugs

Conditions:   Drug Effect Disorder;   Platelet Procoagulant Activity Deficiency
Intervention:  
Sponsor:   Beijing Anzhen Hospital
Active, not recruiting - verified July 2015

Randomized Comparison of Radiological Exposure With TRIPTable® in Patients With Acute Coronary Syndromes

Conditions:   Acute Coronary Syndromes;   Angioplasty, Transluminal, Percutaneous Coronary
Interventions:   Device: TripTable;   Device: Radial;   Device: Femoral
Sponsor:   Marilia Medicine School
Active, not recruiting - verified July 2015

Computed TomogRaphic Evaluation of Atherosclerotic DEtermiNants of Myocardial IsChEmia

Condition:   Myocardial Ischemia
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2015

Dual Energy CT for Ischemia Determination Compared to "Gold Standard" Non-Invasive and Invasive Techniques

Condition:   Ischemia
Intervention:   Procedure: CT and stress test
Sponsors:   Weill Medical College of Cornell University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2015

Intra-aortic Balloon Pump in Extensive Myocardial Infarction With Persistent Ischemia

Conditions:   Acute Myocardial Infarction;   Persisting Ischemia;   No Reflow
Intervention:   Device: Intra-aortic balloon pump
Sponsors:   Lokien van Nunen;   Stichting Toegepaste Wetenschappen (project number 11052);   Maquet Cardiovascular
Recruiting - verified July 2015

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL112;   Biological: Placebo
Sponsor:   CSL Behring
Recruiting - verified July 2015

HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt

Conditions:   Coronary Arteriosclerosis;   Non ST Segment Elevation Acute Coronary Syndrome
Interventions:   Device: OrbusNeich Combo stent™;   Device: Everolimus Eluting Stent (EES)
Sponsors:   OrbusNeich;   OrbusNeich Medical K.K.;   Duke Clinical Research Institute
Recruiting - verified July 2015

Safety & Efficacy of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia (ATHENA II)

Condition:   Myocardial Ischemia
Interventions:   Device: Celution System;   Device: Placebo
Sponsor:   Cytori Therapeutics
Active, not recruiting - verified December 2014

Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis

Condition:   Saphenous Vein Graft Disease
Interventions:   Drug: Aspirin;   Drug: Ticagrelor
Sponsors:   Boca Raton Regional Hospital;   AstraZeneca
Recruiting - verified July 2015

Observational Study to Evaluate Short and Long-term Safety of the ABSORB Scaffold

Condition:   Coronary Artery Stenosis
Intervention:   Device: ABSORB Scaffold
Sponsors:   IHF GmbH - Institut für Herzinfarktforschung;   Abbott Vascular
Recruiting - verified July 2015

A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes

Conditions:   Diabetic Nephropathies;   Coronary Artery Disease
Interventions:   Drug: Allopurinol;   Drug: Placebo
Sponsors:   Alessandro Doria;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Juvenile Diabetes Research Foundation;   Joslin Diabetes Center;   University of Minnesota - Clinical and Translational Science Institute;   University of Colorado, Denver;   University of Michigan;   University of Toronto;   Feinberg School of Medicine, Northwestern University;   Albert Einstein College of Medicine of Yeshiva University;   Steno Diabetes Center;   Washington University School of Medicine;   University of Washington;   Emory University;   University of Calgary;   University of Alberta;   University of Texas Southwestern Medical Center
Recruiting - verified May 2015

Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Saint Luke's Health System;   Boston Scientific Corporation
Active, not recruiting - verified July 2015

Cardiology-Emergency Medicine Cardiac Biomarker Research Initiative

Condition:   Acute Coronary Syndrome
Intervention:   Other: OBSERVATIONAL REGISTRY
Sponsor:   Henry Ford Health System
Completed - verified July 2015

Evaluation of the Biological Response to Clopidogrel in Patients With Ischemic Stroke

Conditions:   Brain Ischemia;   Ischemic Attack
Intervention:   Drug: Clopidogrel
Sponsors:   Centre Hospitalier Universitaire de Saint Etienne;   Groupe de Recherche sur la Thrombose
Recruiting - verified July 2015

Prospective, Randomized, Multicenter Study to Assess the Safety and Effectiveness of the Orsiro Sirolimus-eluting Stent

Condition:   Coronary Artery Disease
Interventions:   Device: Abbott Laboratories Xience;   Device: Biotronik Orsiro
Sponsor:   Biotronik AG
Active, not recruiting - verified July 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ ABSORB CHINA Randomized Controlled Trial (RCT)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: XIENCE V EECSS;   Device: ABSORB BVS System
Sponsor:   Abbott Vascular
Active, not recruiting - verified July 2015

XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS) China Single-Arm Study

Conditions:   Angioplasty;   Cardiovascular Disease;   Chronic Coronary Occlusion;   Coronary Artery Bypass Graft (CABG);   Coronary Artery Disease;   Coronary Heart Disease;   Coronary Restenosis;   Myocardial Infarction;   Myocardial Ischemia;   Stent Thrombosis;   Vascular Disease
Intervention:   Device: XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS)
Sponsor:   Abbott Vascular
Active, not recruiting - verified July 2015

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified July 2015

Brilinta DaYu Study

Condition:   Acute Coronary Syndrome
Intervention:   Drug: Ticagrelor
Sponsor:   AstraZeneca
Active, not recruiting - verified July 2015

China Acute Myocardial Infarction Registry

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Cardiovascular Institute & Fuwai Hospital
Recruiting - verified July 2015

Screening for Abdominal Aortic Aneurysm Using a Portable Transthoracic Echocardiography Among Patients With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   HaEmek Medical Center, Israel
Recruiting - verified July 2015

Circulating miR-126 as a Novel Biomarker for Post Myocardial Infarction Remodeling

Conditions:   Myocardial Infarction;   Left Ventricular Remodeling;   miR-126
Intervention:  
Sponsors:   Qilu Hospital;   Shandong Provincial Qianfoshan Hospital Affiliated to Shandong University;   Jinan Central Hospital Affiliated to Shandong University;   Shandong Provincial Hospital Affiliated to Shandong University;   The Second Hospital of Shandong University;   Ruijin Hospital;   Qingdao University;   Shandong Provincial Medical Imaging Institute of Shandong University;   The First Affiliated Hospital of Zhengzhou University;   Heze Municipal Hospital;   Jining Hospital of Traditional Chinese Medicine;   Qihe People's Hospital;   Central Hospital of Zibo;   Weihai Municipal Hospital;   Beijing Friendship Hospital Affiliated to Capital Medical University;   Affiliated Hospital of Binzhou Medical Universty;   Beijing Hospital
Completed - verified July 2015

Vascular Events In Surgery patIents cOhort evaluatioN - Cardiac Surgery

Conditions:   Vascular Death;   Myocardial Infarction;   Stroke;   Cardiac Surgery
Intervention:  
Sponsors:   Population Health Research Institute;   Abbott Diagnostics Division
Recruiting - verified July 2015

GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation

Condition:   Coronary Artery Disease (CAD)
Interventions:   Drug: Ticagrelor;   Drug: Acetylsalicylic Acid;   Drug: Clopidogrel
Sponsors:   ECRI bv;   Biosensors International;   AstraZeneca;   The Medicines Company
Recruiting - verified July 2015

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Cardiac Valve Disease
Interventions:   Device: SternaLock Blue closure system;   Device: Suture Wire
Sponsor:   Biomet, Inc.
Active, not recruiting - verified July 2015

Myocardial Infarction - Stress Prevention Intervention

Conditions:   Stress Disorders, Post-Traumatic;   Myocardial Infarction
Interventions:   Behavioral: Minimal behavioral intervention;   Behavioral: Control intervention
Sponsors:   University Hospital Inselspital, Berne;   Swiss National Science Foundation;   University of Bern;   University of Zurich
Recruiting - verified July 2015

ABSORB III Randomized Controlled Trial (RCT)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: Absorb BVS;   Device: XIENCE
Sponsor:   Abbott Vascular
Recruiting - verified July 2015

Clinical Evaluation of the CADence Device in Detection of Coronary Artery Diseases

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   AUM Cardiovascular, Inc.
Recruiting - verified July 2015

Proton Radiation for Stage II/III Breast Cancer

Conditions:   Breast Cancer;   Breast Neoplasm;   Breast Tumor;   Cancer of the Breast
Intervention:   Radiation: Proton Radiotherapy
Sponsor:   Proton Collaborative Group
Recruiting - verified July 2015

Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasis

Conditions:   Psoriasis;   Vascular Inflammation;   Coronary Atherosclerosis
Interventions:   Biological: Adalimumab;   Other: Placebo
Sponsors:   Innovaderm Research Inc.;   Abbott;   Montreal Heart Institute
Active, not recruiting - verified July 2015

Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)

Conditions:   Acute Coronary Syndrome;   Angina Pectoris;   Angina, Unstable;   Myocardial Infarction;   Coronary Artery Disease;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Orsiro;   Device: Synergy;   Device: Resolute Integrity
Sponsor:   Cardio Research Enschede BV
Enrolling by invitation - verified July 2015

An Evaluation of Clinical Pharmacist-led Intervention on Clinical Outcomes in Patients With Ischemic Stroke

Condition:   Stroke
Interventions:   Other: Intervention (CPCRS) Group;   Other: Placebo
Sponsor:   Kaiser Permanente
Active, not recruiting - verified July 2015

Assessment of Risk in Chronic Airways Disease Evaluation

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Intervention:  
Sponsors:   Cardiff University;   GlaxoSmithKline
Active, not recruiting - verified July 2015

Depression Care for Hospitalized Coronary Heart Disease Patients: Prospective Cohort Study

Conditions:   Coronary Heart Disease;   Depression
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   University Hospital Muenster
Active, not recruiting - verified July 2015

A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System

Conditions:   Congestive Heart Failure;   Left Ventricular (LV) Systolic Dysfunction
Intervention:   Device: CardioKinetix Parachute Implant and All Appropriate Medical Therapy (AAMT)
Sponsor:   CardioKinetix, Inc
Recruiting - verified July 2015

The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes

Conditions:   Coronary Artery Disease;   Diabetes Mellitus, Type 2
Interventions:   Drug: Liraglutide;   Drug: Placebo
Sponsor:   Haugaard, Steen Bendix, M.D., DMSc
Completed - verified July 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Pericardic Adipose Pedicle Transposition Over the Myocardial Infarct (adiFLAP Trial)

Condition:   Myocardial Infarction
Interventions:   Procedure: Pericardial adipose pedicle (adiFLAP) transposition.;   Other: Control
Sponsor:   Germans Trias i Pujol Hospital
Completed - verified July 2015

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Recruiting - verified July 2015

Impact of Adalimumab Therapy on Brachial Endothelial Function and Large Artery Stiffness in Patients With Rheumatoid Arthritis

Condition:   Rheumatoid Arthritis
Interventions:   Device: transthoracic echocardiographic;   Device: Doppler ultrasound.;   Biological: blood samples
Sponsor:   Assistance Publique Hopitaux De Marseille
Completed - verified September 2014

The CONFIRM Registry

Conditions:   Atherosclerosis;   Coronary Artery Disease;   Cardiovascular Disease
Intervention:  
Sponsor:   Weill Medical College of Cornell University
Enrolling by invitation - verified July 2015

Beijing Percutaneous Coronary Intervention Registry

Condition:   Coronary Heart Disease
Intervention:  
Sponsor:   Cardiovascular Institute & Fuwai Hospital
Recruiting - verified July 2015

Glucagon-like Peptide 1 Agonist Exenatide for Improved Glucose Control and Cardiac Function in Diabetic Patients With Aortocoronary Bypass

Conditions:   Coronary Artery Disease;   Left Ventricular Dysfunction;   Type 2 Diabetes Mellitus
Intervention:   Drug: Exenatide
Sponsors:   Charles University, Czech Republic;   Eli Lilly and Company
Completed - verified July 2015

Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic Shock

Condition:   Cardiogenic Shock
Intervention:   Drug: epinephrine/norepinephrine
Sponsor:   Central Hospital, Nancy, France
Recruiting - verified July 2015

DUrable Polymer-based STent CHallenge of Promus Element Versus ReSolute Integrity in an All Comers Population

Conditions:   Acute Coronary Syndrome;   Angina Pectoris;   Angina, Unstable;   Myocardial Infarction;   Coronary Artery Disease;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Resolute Integrity (Zotarolimus-eluting stent);   Device: Promus Element (Everolimus-eluting stent)
Sponsor:   Cardio Research Enschede BV
Completed - verified July 2015

A 30 Day Study to Evaluate Efficacy and Safety of Pre-hospital vs. In-hospital Initiation of Ticagrelor Therapy in STEMI Patients Planned for Percutaneous Coronary Intervention (PCI)

Conditions:   Myocardial Infarction;   Segment Elevation Myocardial Infarction (STEMI)
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsor:   AstraZeneca
Completed - verified July 2015

Safety and Efficacy Registry of Yinyi Stent

Condition:   Coronary Artery Disease
Intervention:   Device: Yinyi stent
Sponsor:   Shanghai Jiao Tong University School of Medicine
Completed - verified October 2008

Post Ten Year Follow up Assessment of a Phase I Trial of Angiogenic Gene Therapy

Conditions:   Coronary Artery Disease;   Ischemia
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   Stony Brook University
Completed - verified July 2015

A Trial of Bare Metal Stent - Cobalt Chromium Versus Stent Coating With Sirolimus

Condition:   Coronary Artery Disease
Interventions:   Device: DRUG ELUTING STENT;   Device: BARE METAL STENT
Sponsor:   Scitech Produtos Medicos Ltda
Completed - verified July 2015

The Real-World Endeavor Resolute Versus XIENCE V Drug-Eluting Stent Study in Twente

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina Pectoris;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Endeavor Resolute (Biolinx-based Zotarolimus-eluting stent);   Device: Xience V (Everolimus-eluting stent)
Sponsor:   Cardio Research Enschede BV
Completed - verified July 2015

A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease

Condition:   Cardiovascular Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Terminated - verified July 2015

Role of Vitamin D in Secondary Prevention of Cardiovascular Events

Condition:   Cardiovascular Disease
Interventions:   Drug: Cholecalciferol;   Drug: Placebo
Sponsor:   Creighton University
Completed - verified July 2015

Endothelial Function and Heart Rate Variability After Stenting

Condition:   Restenosis or Adverse Cardiovascular Event
Intervention:   Device: stent implantation in coronary artery
Sponsor:   Helse Stavanger HF
Completed - verified October 2009

Stress Management and Biomarkers of Risk in Cardiac Rehabilitation

Condition:   Coronary Heart Disease
Interventions:   Behavioral: SMT-enhanced Cardiac Rehabilitation;   Behavioral: Standard Cardiac Rehabilitation
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified July 2015

Strengthening Transplantation Effects of Bone Marrow Mononuclear Cells With Atorvastatin in Myocardial Infarction

Conditions:   Myocardial Infarction;   Stem Cell Transplantation;   Angioplasty, Transluminal, Percutaneous Coronary
Intervention:   Drug: Atorvastatin and mononuclear cells transplantation
Sponsor:   Cardiovascular Institute & Fuwai Hospital
Enrolling by invitation - verified July 2015

Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department

Conditions:   Acute Myocardial Infarction;   Chest Pain;   Acute Coronary Syndrome
Intervention:  
Sponsor:   Biosite
Withdrawn - verified July 2015

Cardiovascular Disease Study

Condition:   Spinal Cord Injury
Interventions:   Procedure: 2 hour Oral Glucose Tolerance Test;   Procedure: Fat Meal Test
Sponsors:   Department of Veterans Affairs;   Kessler Foundation
Recruiting - verified July 2015

Coronary Artery Disease Management Using Multislice Computed Tomography and Magnetic Resonance Imaging

Condition:   Coronary Artery Disease
Interventions:   Procedure: CT/MR;   Procedure: Catheterization
Sponsors:   Charite University, Berlin, Germany;   University Hospital Muenster;   Medizinische Hochschule Hannover, Eva Schönenberger, MD;   University of Freiburg
Recruiting - verified July 2015

Chest Imaging, Breath, and Biomarkers in a Screening Trial

Condition:   Lung Cancer
Intervention:   Device: chest x-ray with or without CAD, lose dose CT scan
Sponsor:   The Cleveland Clinic
Completed - verified July 2015

Prospective Observational Epidemiologic Study of Maraviroc's Safety

Condition:   Human Immunodeficiency Virus
Interventions:   Drug: Maraviroc along with an optimized background antiretroviral drug regimen;   Drug: Optimized background antiretroviral drug regimen without maraviroc
Sponsors:   ViiV Healthcare;   Pfizer
Active, not recruiting - verified July 2015

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Condition:   Coronary Heart Disease
Interventions:   Drug: Evidence-based medical care for Acute Coronary Syndrome;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified July 2015

Standard Drug Therapy vs. Implanted Defibrillator for Primary Prevention of Sudden Cardiac Death

Conditions:   Coronary Heart Disease;   Congestive Heart Failure;   Ventricular Dysfunction;   Low Cardiac Output;   Sudden Cardiac Death
Interventions:   Drug: Optimized medical therapy;   Device: Implantable Cardioverter Defibrillator
Sponsors:   St. Michael's Hospital, Toronto;   Institute for Clinical Evaluative Sciences;   Ontario Ministry of Health and Long Term Care
Terminated - verified July 2015

MR, Myocardial Infarct and Heart Failure

Condition:   Heart Failure, Congestive
Intervention:   Procedure: PCI (percutaneous coronary intervention)
Sponsors:   Helse Stavanger HF;   Helse Vest;   Norwegian Foundation for Health and Rehabilitation;   Norwegian Heart and Lung Patient Organization;   Sparebank 1 SR-Bank Gavefond;   Amersham Health
Completed - verified June 2008

Observational Study of the Remodelling Process Following Myocardial Infarct

Conditions:   Heart Failure;   Myocardial Infarct
Intervention:  
Sponsors:   Helse Stavanger HF;   Helse Vest;   Amersham Buchler, GmbH & Co KG
Completed - verified July 2010

Coronary CT Angiography in Asymptomatic Diabetes Mellitus

Condition:   Diabetes Mellitus
Intervention:   Other: Imaging study, No intervention
Sponsors:   Carmel Medical Center;   European Foundation for the Study of Diabetes
Active, not recruiting - verified February 2015

Enhancing the Secondary Prevention of Coronary Artery Disease

Conditions:   Coronary Disease;   Ischemic Heart Disease
Intervention:   Behavioral: Evidence summaries endorsed by local opinion leaders
Sponsors:   University of Alberta;   Heart and Stroke Foundation of Canada;   Alberta Heritage Foundation for Medical Research;   Pfizer
Completed - verified July 2015

SHORTness of Breath In the Emergency Department (SHORTIE)

Conditions:   Acute Myocardial Infarction;   Heart Failure;   Pulmonary Embolism
Intervention:   Device: Triage Profiler S.O.B. Panel
Sponsor:   Biosite
Completed - verified July 2015

Rapid Assessment of Cardiac Markers for the Evaluation of Acute Coronary Syndrome (RACE-ACS)

Condition:   Acute Coronary Syndrome
Intervention:   Device: Triage CardioProfilER (Troponin I, Myoglobin, CK-MB, BNP)
Sponsor:   Biosite
Withdrawn - verified July 2015

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