Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

"SIMULATION MODELING OF CORONARY ARTERY DISEASE: A TOOL FOR CLINICAL DECISION SUPPORT"

Condition:   Management/Treatment of Coronary Artery Disease
Intervention:   Diagnostic Test: CCTA
Sponsors:   Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy;   University of Zurich;   Turku University Hospital;   Azienda USL 12 Versilia;   Federico II University;   Institut Catala de Salut;   Institute of Cardiology, Warsaw, Poland
Completed

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

Condition:   Coronary Atherosclerosis
Interventions:   Device: Cardiac MRI;   Drug: Contrast;   Drug: Beta blocker
Sponsor:   Cedars-Sinai Medical Center
Recruiting

Cardiogoniometry for Detecting Coronary Artery Disease by CT Angiography

Conditions:   Coronary Heart Disease;   Coronary Artery Disease;   Ischemic Heart Disease
Intervention:   Device: Explorer
Sponsors:   Johns Hopkins University;   Enverdis Corp.
Terminated

Comparison of Cardiac Computed Tomography and Vasodilator Stress Magnetic Resonance Imaging Perfusion in Patients With Prior Equivocal Stress Test for Detection of Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Suspended

Imaging-based Diagnosis of Diffuse Coronary Artery Disease and Quantification of Cardiac Remodeling in Obesity

Condition:   Obesity
Intervention:  
Sponsors:   National Heart Centre Singapore;   Singapore General Hospital
Completed

Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry

Conditions:   Coexistence of Cerebral and Coronary Atherosclerosis;   Acute Ischemic Cerebrovascular Disease
Intervention:   Other: observational only- no intervention
Sponsor:   Xuanwu Hospital, Beijing
Recruiting

Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Coronary Disease;   Heart Diseases;   Cardiovascular Diseases;   Arteriosclerosis;   Arterial Occlusive Diseases;   Vascular Diseases
Intervention:   Diagnostic Test: Coronary computed tomography angiography
Sponsors:   National University of Ireland, Galway, Ireland;   GE Healthcare;   HeartFlow, Inc.
Recruiting

Efficacy Study of Oral Nicorandil on Improving Microvascular Function in Female Non-obstructive Coronary Artery Disease (CAD) Participants

Condition:   Non-obstructive Coronary Artery Disease
Intervention:   Drug: Nicorandil
Sponsors:   Merck KGaA, Darmstadt, Germany;   Merck Serono Co., Ltd., China
Terminated

Evaluation of New Specifications (2.25mm) of FirehawkTM in the Treatment of Coronary Heart Disease ( Firehawk_2.25 )

Condition:   Coronary Heart Disease
Intervention:   Device: FirehawkTM 2.25mm
Sponsor:   Shanghai MicroPort Medical (Group) Co., Ltd.
Active, not recruiting

Comparison of the Severity of Coronary Atherosclerosis With Tissue Compliance in Patients Within First Degree Relatives

Condition:   Coronary Artery Disease With Myocardial Infarction
Intervention:   Diagnostic Test: there is not any intervention procedure
Sponsor:   TC Erciyes University
Not yet recruiting

Evaluating Myocardial Ischemia in Chest Pain Using Exercise CMR

Conditions:   Ischemic Heart Disease;   Coronary Artery Disease;   Cardiovascular Diseases;   Myocardial Ischemia;   Coronary Heart Disease
Interventions:   Other: Cardiovascular Magnetic Resonance Imaging with Exercise Bike;   Procedure: Cardiac Catheterization;   Other: Retinal Photography (Optional)
Sponsor:   National Heart Centre Singapore
Recruiting

Pharmaceutical Follow-up of Coronary Heart Disease (CHD) Patients

Condition:   Coronary Heart Disease
Intervention:   Other: Pharmacist follow-up
Sponsors:   Hospital Pharmacy of North Norway Trust;   University of Tromso
Completed

Cruz HBR Registry - Post-market Registry to Evaluate the Safety and Efficacy of the Supraflex Cruz Stent

Condition:   Coronary Artery Disease
Intervention:   Device: Supraflex Cruz Sirolimus-eluting Stent
Sponsors:   Sahajanand Medical Technologies Pvt. Ltd.;   Cardiovascular European Research Center (CERC)
Recruiting

Registry of Coronary Lithotripsy in Spain.

Conditions:   Cardiovascular Diseases;   Arteriosclerosis;   Arterial Occlusive Diseases;   Vascular Diseases;   Coronary Artery Disease
Intervention:   Other: Intracoronary lithotripsy (ICL)
Sponsor:   Fundación EPIC
Recruiting

The Young Heart Study

Conditions:   Atherosclerotic Cardiovascular Disease;   Coronary Artery Disease
Intervention:   Behavioral: Risk Reduction Program
Sponsor:   Northwell Health
Recruiting

BioFreedom French Registry

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Biosensors Europe SA;   European Cardiovascular Research Center
Active, not recruiting

Effects of VitamIN K2 supplementaTion on PET/MRI in Carotid Artery Disease

Conditions:   Coronary Artery Disease;   Carotid Artery Disease
Interventions:   Dietary Supplement: Menaquinone-7;   Other: Placebo
Sponsors:   Academisch Ziekenhuis Maastricht;   Horizon 2020 - European Commission
Not yet recruiting

Hybrid Coronary Revascularization Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: Hybrid Coronary Revascularization (isolated LIMA-LAD);   Device: Hybrid Coronary Revascularization (PCI);   Device: Percutaneous Coronary Intervention
Sponsors:   Emilia Bagiella;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting

eHealth Intervention to Manage Depression and Anxiety in Patients With Ischemic Heart Disease

Condition:   Depression, Anxiety
Interventions:   Other: eHealth intervention;   Other: Usual Care
Sponsors:   University of Southern Denmark;   Odense Patient Data Explorative Network
Recruiting

VEST III PMS Clinical Protocol

Condition:   Coronary Artery Disease
Interventions:   Device: VEST External Support;   Procedure: Coronary Artery Bypass Surgery
Sponsor:   Vascular Graft Solutions Ltd.
Completed

Implementation of CYP2C19 Genotyping to Guide Antiplatelet Therapy

Condition:   Coronary Artery Disease
Intervention:   Device: SpartanRX
Sponsors:   University of Florida;   National Institutes of Health (NIH);   National Human Genome Research Institute (NHGRI)
Active, not recruiting

DNA Repair in Patients With Stable Angina.

Conditions:   Coronary Artery Disease;   Coronary Arteriosclerosis;   DNA Damage;   DNA Repair Abnormality
Intervention:  
Sponsor:   University Hospital Southampton NHS Foundation Trust
Active, not recruiting

PeRcutaneous cOronary Intervention of Native Coronary arTery Versus Venous Bypass Graft in Patients With Prior CABG

Condition:   Coronary Artery Disease
Intervention:   Procedure: Percutaneous coronary intervention
Sponsor:   VU University Medical Center
Recruiting

The Genomic Medicine at VA Study

Conditions:   Coronary Artery Disease;   Atrial Fibrillation;   Type 2 Diabetes;   Colorectal Cancer;   Breast Cancer;   Prostate Cancer
Intervention:   Diagnostic Test: Polygenic risk score (PRS)
Sponsors:   Harvard Medical School;   VA Boston Healthcare System
Recruiting

Non Alcoholic Fatty Liver Disease and Coronary Heart Disease in Type 2 Diabetes Patients

Condition:   Nonalcoholic Steatohepatitis
Intervention:  
Sponsor:   University of California, San Diego
Completed

Impact of Spiroergometry Parameters as Diagnostic Marker of Cardiac Ischemia in Pts. With Stable Angina Compared to FFR.

Condition:   Stable Angina
Intervention:   Diagnostic Test: ergospirometry
Sponsor:   Jena University Hospital
Recruiting

BioFreedom Pharmacokinetic Study

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:   Device: BioFreedom™ BA9™ drug-coated stent
Sponsor:   Biosensors Europe SA
Completed

Effects of Curcumin on Markers of Cardiovascular Risk in Patients With CAD

Conditions:   Coronary Artery Disease;   Oxidative Stress;   Inflammation
Intervention:   Dietary Supplement: Curcumin
Sponsor:   Universidade Federal Fluminense
Not yet recruiting

Keep bIfurcation Single Stenting Simple

Condition:   Coronary Disease
Interventions:   Procedure: Side branch protection/ballooning;   Procedure: No side branch protection/ballooning
Sponsor:   Ceric Sàrl
Not yet recruiting

Myocardial Perfusion Imaging by 15O-H2O PET/CT

Condition:   Ischemic Heart Disease
Intervention:  
Sponsor:   University of Aarhus
Not yet recruiting

Pharmacist Follow-up, a Qualitative Study of Patient Experience

Conditions:   Patient Satisfaction;   Patient Preference
Intervention:  
Sponsors:   Hospital Pharmacy of North Norway Trust;   University of Tromso
Completed

Personalized Vs. Standard Duration of Dual Antiplatelet Therapy and New-generation Polymer-Free vs- Biodegradable-Polymer DES

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome;   Chronic Coronary Syndrome;   Myocardial Infarction
Interventions:   Device: Percutaneous coronary intervention with implantation of amphilimus-eluting stents for coronary artery disease.;   Device: Percutaneous coronary intervention with implantation of everolimus-eluting stents for coronary artery disease.;   Drug: Personalized DAPT duration;   Drug: Standard DAPT duration
Sponsors:   Federico II University;   AdvicePharma Group
Recruiting

FiO2 and Outcomes After OPCAB (the CARROT Trial)

Condition:   Coronary Artery Disease
Intervention:   Other: Fraction of inspired oxygen level
Sponsors:   Seoul National University Hospital;   Asan Medical Center;   Severance Hospital
Recruiting

XLIMus Drug Eluting Stent: a randomIzed Controlled Trial to Assess Endothelization

Condition:   Coronary Artery Disease
Interventions:   Device: Xlimus DES Implantation during coronary angioplasty;   Device: Synergy DES Implantation during coronary angioplasty
Sponsors:   Cardionovum GmbH;   Mediolanum Cardio Research
Recruiting

A Clinical Trial to Assess the SYNERGY 48 mm Stent System for the Treatment of Atherosclerotic Lesion(s)

Condition:   Coronary Artery Disease
Intervention:   Device: SYNERGY 48 mm
Sponsor:   Boston Scientific Corporation
Active, not recruiting

The Direct III Post Market Study

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Svelte Medical Systems, Inc.
Completed

Medtronic RevElution Trial

Condition:   Coronary Artery Disease
Intervention:   Device: Polymer-free DES (Drug Eluting Stent)
Sponsor:   Medtronic Vascular
Completed

Safety and Efficacy Study of the Svelte Drug-Eluting Coronary Stent Delivery System

Condition:   Coronary Artery Disease
Intervention:   Device: Coronary Stenting
Sponsor:   Svelte Medical Systems, Inc.
Completed

Observational Study of OCT in a Patients Undergoing FFR

Condition:   Coronary Artery Disease
Intervention:   Device: OCT stent guidance
Sponsor:   Abbott Medical Devices
Completed

Clinical Effect of No-touch Harvesting Technique in OPCABG

Conditions:   Coronary Artery Disease;   Graft Failure
Interventions:   Procedure: Conventional vein harvesting technique;   Procedure: no-touch vein harvesting technique
Sponsors:   Beijing Anzhen Hospital;   Beijing Municipal Administration of Hospitals
Recruiting

Distal Evaluation of Functional Performance With Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

Conditions:   Coronary Artery Disease;   Ischemic Heart Disease
Interventions:   Device: Philips SyncVision system with Philips pressure wires;   Procedure: standard of care angiographically-guided PCI
Sponsor:   Philips Clinical & Medical Affairs Global
Not yet recruiting

Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

Condition:   Sickle Cell Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease

Conditions:   Coronary Artery Disease;   Myocarditis;   Infiltrative Cardiomyopathy;   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Aortic Valve Stenosis;   Aortic Valve Regurgitation;   Pericardial Effusion;   Congenital Heart Disease;   Vascular Anomaly
Intervention:  
Sponsor:   McGill University Health Centre/Research Institute of the McGill University Health Centre
Recruiting

Biolimus A9™ (BA9™) Drug Coated Balloon (DCB) Study

Conditions:   Coronary Artery Disease;   In-Stent Restenosis
Interventions:   Device: Biolimus A9 Drug Coated Balloon;   Device: SeQuent Please Paclitaxel Drug Coated Balloon
Sponsor:   Biosensors Europe SA
Not yet recruiting

Cytisine Compared to Combination NRT in Relapsed Smokers

Conditions:   Smoking Cessation;   Coronary Artery Disease
Interventions:   Drug: Cytisine;   Drug: Nicoderm C-Q Transdermal Product;   Drug: Nicorette Lozenge Product
Sponsor:   Ottawa Heart Institute Research Corporation
Not yet recruiting

Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting Surgery

Conditions:   Surgery;   Coronary Artery Disease
Interventions:   Drug: Rocuronium;   Drug: Neostigmine;   Drug: Glycopyrrolate;   Drug: Sugammadex
Sponsor:   West Virginia University
Recruiting

Diagnostic Accuracy of Electrocardiogram for Acute Coronary Occlusion Resulting in Myocardial Infarction

Conditions:   Myocardial Infarction;   Acute Coronary Syndrome;   Coronary Artery Disease
Intervention:   Radiation: Coronary angiogram
Sponsors:   Yeditepe University;   Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Completed

Dexmedetomidine and Outcomes of Cardiac Surgery (DOCS)

Conditions:   Heart Valve Diseases;   Coronary Artery Disease
Interventions:   Drug: dexmedetomidine;   Drug: placebo
Sponsor:   Xijing Hospital
Completed

Evaluating New Radiation Techniques for Cardiovascular Imaging

Condition:   Coronary Disease
Intervention:   Device: The Toshiba Aquilion ONE CT system
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

FUnctional diagnoSIs of corONary Stenosis (FUSION)

Conditions:   Coronary Artery Disease;   Coronary Stenosis
Interventions:   Procedure: ICA (Invasive Coronary Angiography);   Procedure: OCT;   Procedure: FFR (Fractional Flow Reserve);   Other: VFR Analysis
Sponsor:   Abbott Medical Devices
Recruiting

Disrupt CAD III With the Shockwave Coronary IVL System

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:   Device: Lithotripsy
Sponsor:   Shockwave Medical, Inc.
Active, not recruiting

Alternate Day Fasting for Weight Loss, Weight Maintenance and Cardio-protection

Conditions:   Coronary Heart Disease;   Obesity;   Weight Loss
Interventions:   Other: Alternate day fasting;   Other: Calorie restriction;   Other: Control diet
Sponsors:   University of Illinois at Chicago;   Pennington Biomedical Research Center;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Effect of Colchicine in Patients With Myocardial Infarction

Conditions:   Myocardium; Injury;   Myocardial Infarction;   Myocardial Ischemia
Interventions:   Drug: Colchicine;   Drug: Placebo oral tablet
Sponsors:   Shifa Tameer-e-Millat University;   Rawalpindi Institute of Cardiology
Enrolling by invitation

HIV-HEART Aging Study (15 Year Follow up)

Conditions:   HIV Infections;   Coronary Disease;   Myocardial Infarction;   HIV Encephalopathy;   Aging;   Heart Failure;   Weight Gain
Intervention:  
Sponsor:   University Hospital, Essen
Recruiting

Physiologic Assessment of Coronary Stenosis Following PCI

Conditions:   Coronary Artery Disease;   Coronary Stenosis;   Angina, Unstable;   Angina, Stable
Intervention:   Diagnostic Test: iFR pullback
Sponsors:   Volcano Corporation;   Duke Clinical Research Institute;   Cardiovascular Research Foundation, New York
Completed

Effects of Erector Spinae Plane Block Method Used in Pain Management in Heart Surgery on Vascular Diameters

Conditions:   Coronary Artery Disease;   Erector Spinae Plane Block;   Bypass Extremity Graft
Intervention:   Procedure: Erector Spinae Plane Block
Sponsor:   Koç University
Recruiting

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Population Health Research Institute;   Janssen Research & Development, LLC
Active, not recruiting

Bright Light Therapy in Patients Undergoing Cardiac Surgery

Condition:   Myocardial Ischemia
Interventions:   Device: Day Light;   Device: Placebo light
Sponsor:   University of Colorado, Denver
Recruiting

Radiographic Imaging Validation and EvALuation for Angio iFR (ReVEAL iFR)

Conditions:   Cardiac Ischemia;   Coronary Artery Disease;   Coronary Stenosis
Intervention:   Diagnostic Test: iFR
Sponsor:   Volcano Corporation
Recruiting

Coronary Plaque Geometry and Acute Coronary Syndromes

Conditions:   Coronary Stenosis;   Acute Coronary Syndrome;   Acute Myocardial Infarction;   Atherosclerosis;   Atheromatous Plaques
Intervention:   Diagnostic Test: CCTA
Sponsors:   Cardio Med Medical Center;   University of Targu Mures, Romania;   University Hospital of Targu Mures, Romania
Recruiting

Impact of Daylight on Patients With Acute Myocardial Infarction

Conditions:   Coronary Arteriosclerosis;   Myocardial Infarction
Interventions:   Other: Day Light;   Other: Room Light
Sponsor:   University of Colorado, Denver
Recruiting

Minority Health Genomics and Translational Research Bio-Repository Database (MH-GRID)-2.0

Condition:   Hypertension
Intervention:  
Sponsors:   National Human Genome Research Institute (NHGRI);   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Chronic Total Occlusion Percutaneous Coronary Intervention Study

Conditions:   Chronic Total Occlusion;   Ischemic Heart Disease;   Chronic Total Occlusion of Coronary Artery
Interventions:   Procedure: Chronic Total Occlusion Revascularization;   Device: GuideLiner® V3 catheter, TrapLiner® catheter, Turnpike® catheter
Sponsors:   Vascular Solutions, Inc;   Teleflex;   Bright Research Partners
Recruiting

Concordance Between FFR and iFR for the Assessment of Intermediate Lesions in the Left Main Coronary Artery. A Prospective Validation of a Default Value for iFR

Conditions:   Coronary Artery Disease;   Left Main Coronary Artery Stenosis;   Left Main Coronary Artery Disease;   Restenosis, Coronary
Intervention:   Other: Indication of revascularization
Sponsor:   Fundación EPIC
Recruiting

Biomarker-based Prognostic Assessment

Conditions:   Acute Coronary Syndrome;   Stable Angina
Intervention:   Biological: Plasma biomarker
Sponsors:   Qilu Hospital of Shandong University;   Peking University Third Hospital;   Chinese PLA General Hospital Hospital;   Peking University First Hospital;   Central Hospital of Zibo
Recruiting

De-implementation of Low-value Pharmacological Prescriptions

Conditions:   Inappropriate Prescribing;   Implementation Science;   Behavioral Sciences
Interventions:   Behavioral: Intuitive de-implementation;   Behavioral: Reflexive de-implementation;   Behavioral: Passive dissemination
Sponsors:   Basque Health Service;   Health Department of the Basque Government
Not yet recruiting

MRI of Myocardial Infarction

Conditions:   Myocardial Infarction;   Myocardial Ischemia;   Myocardial Injury;   Myocardial Fibrosis;   Myocardial Reperfusion Injury;   Myocardial Edema;   Myocardial Necrosis;   Heart Failure;   Ischemic Heart Disease;   Ischemic Cardiomyopathy;   Hemorrhage
Intervention:  
Sponsor:   University of Pennsylvania
Recruiting

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

Conditions:   Cardiomyopathy;   Coronary Artery Disease;   Congestive Heart Failure;   Myocardial Infarction
Interventions:   Device: Implantable Cardioverter Defibrillator;   Other: Optimal Medical Therapy
Sponsor:   VA Office of Research and Development
Active, not recruiting

Early Detection of Cardiovascular Disease

Conditions:   Atheroma;   Cardiac Disease;   Vascular Diseases;   Atherosclerosis;   Myocardial Infarction;   Acute Coronary Syndrome
Intervention:   Other: Ultrasound
Sponsors:   Dr. Amer Johri;   Lantheus Medical Imaging
Recruiting

FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease

Conditions:   Coronary Artery Disease;   NSTEMI - Non-ST Segment Elevation MI;   Fractional Flow Reserve, Myocardial;   Myocardial Revascularization;   Percutaneous Coronary Intervention
Interventions:   Procedure: Ischemia driven revascularization;   Other: Usual care group
Sponsors:   Zuyderland Medisch Centrum;   Maastricht University Medical Center;   Radboud University;   Jeroen Bosch Ziekenhuis;   VieCuri Medical Centre;   Gottsegen György Országos Kardiológiai Intézet;   Bács-Kiskun County Teaching Hospital
Recruiting

Myocardial Infarction, COmbined-device, Recovery Enhancement Study

Conditions:   Acute Myocardial Infarction;   Coronary Artery Disease;   Acute Coronary Syndrome;   Myocardial Infarction
Intervention:   Device: Corrie Digital Health platform
Sponsors:   Johns Hopkins University;   Apple Inc.;   iHealth
Completed

Leaders Free III: BioFreedom™ Clinical Trial

Conditions:   Cardiac Death;   Myocardial Infarction;   Stent Thrombosis;   Bleeding;   Mortality
Intervention:   Device: BioFreedom™ BA9™ drug-coated stent
Sponsors:   Biosensors Europe SA;   European Cardiovascular Research Center
Active, not recruiting

Safety of Terminating the Prescription of Aspirin After Left Atrial Appendage Closure

Conditions:   Atrial Fibrillation;   Stroke;   Bleeding
Interventions:   Drug: Aspirin Tablet;   Drug: Placebo
Sponsor:   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Recruiting

Factors Influencing Morbi-mortality in Right Anterior Minithoracotomy Approch for Aortic Valve Replacement

Condition:   Aortic Valve Disease
Intervention:   Procedure: Aortic valve replacement
Sponsor:   Centre Hospitalier La Chartreuse
Completed

Impact of Evolocumab on the Effects of Clopidogrel in Patients With High On-Treatment Platelet Reactivity

Condition:   Atherosclerotic Cardiovascular Disease
Interventions:   Drug: Evolocumab;   Other: Placebo
Sponsors:   University of Florida;   Amgen
Recruiting

Angiotensin-(1-7) in Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Drug: Angiotensin 1-7;   Drug: Saline
Sponsor:   Milton S. Hershey Medical Center
Recruiting

The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol

Condition:   CoVid 19 Positive
Interventions:   Drug: Hydroxychloroquine, Azithromycin;   Drug: Hydroxychloroquine, Doxycycline;   Drug: Hydroxychloroquine, Clindamycin;   Drug: Hydroxychloroquine, Clindamycin, Primaquine - low dose.;   Drug: Hydroxychloroquine, Clindamycin, Primaquine - high dose.;   Drug: Remdesivir;   Drug: Tocilizumab;   Drug: Methylprednisolone;   Drug: Interferon-Alpha2B;   Drug: Losartan;   Drug: Convalescent Serum
Sponsor:   The Camelot Foundation
Enrolling by invitation

Selected Disorders and Sleep Bruxism

Conditions:   Sleep Bruxism;   Hypertension;   Thyroid Dysfunction;   Mental Status Change;   Sleep Apnea;   Sleep Disorders;   Cardiovascular Risk Factor;   Cardiovascular Diseases;   Temporomandibular Disorder
Intervention:   Drug: Opipramol
Sponsor:   Wroclaw Medical University
Enrolling by invitation

Study of Dutogliptin in Combination With Filgrastim in Post-Myocardial Infarction

Conditions:   Acute Myocardial Infarction;   Acute Myocardial Ischemia;   STEMI - ST Elevation Myocardial Infarction
Interventions:   Drug: Dutogliptin Tartrate;   Drug: Filgrastim Injectable Product;   Drug: Placebos
Sponsor:   Recardio, Inc.
Enrolling by invitation

The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS)

Condition:   ASCVD
Intervention:  
Sponsors:   Amgen;   Duke Clinical Research Institute
Recruiting

Low-dose Interleukin-2 for the Reduction of Vascular Inflammation in Acute Coronary Syndromes - IVORY

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Interleukin-2 [IL-2];   Other: Placebo Dextrose 5% solution
Sponsor:   Cambridge University Hospitals NHS Foundation Trust
Not yet recruiting

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Intervention:   Device: Orsiro DES
Sponsor:   Biotronik, Inc.
Recruiting

Role of Microparticles in Covid-19 Infection

Condition:   COVID-19
Intervention:   Other: Blood sample
Sponsor:   University Hospital, Strasbourg, France
Not yet recruiting

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Baim Institute for Clinical Research;   Medstar Health Research Institute
Active, not recruiting

Li-Hep vs. Non-Li-Hep Coated Transfer Device

Conditions:   Acute Coronary Syndrome;   Chest Pain;   Myocardial Infarction;   Cardiac Ischemia
Intervention:   Device: Siemens® Point-of-care high sensitibe troponin I analyzer
Sponsors:   VieCuri Medical Centre;   Siemens Corporation, Corporate Technology
Recruiting

Enhancing Cardiac Rehabilitation Through Behavioral Nudges

Conditions:   Acute Myocardial Infarction;   Percutaneous Coronary Intervention;   Coronary Artery Disease;   Valvular Disease;   Chronic Stable Angina;   Chronic Stable Heart Failure
Interventions:   Other: Hospital-based CR + Movn Application;   Other: Choice of Hospital or home-based CR + Movn Application;   Other: Hospital-based CR + Movn Application + Nudge;   Other: Choice of Hospital or home-based CR + Movn Application + Nudge
Sponsor:   Denver Health and Hospital Authority
Recruiting

Comparison of Fingerstick Versus Venous Sample for Troponin I.

Conditions:   Chest Pain;   Myocardial Infarction;   Myocardial Ischemia;   Heart Attack
Intervention:   Device: POC troponin analysis.
Sponsors:   VieCuri Medical Centre;   Siemens Healthcare Diagnostics Inc;   Minicare B.V. (has been taken over by Siemens Healthcare Diagnostics Inc at the end of 2019)
Active, not recruiting

Catheter Ablation for Nonsustained Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy

Conditions:   Ventricular Tachycardia;   Ischemic Cardiomyopathy;   Reduced LVEF
Interventions:   Procedure: VT ablation;   Other: medication
Sponsor:   Heinrich-Heine University, Duesseldorf
Recruiting

The Benefit of Local Anesthesia at the Sternum in Patients With Coronary Surgery

Condition:   Coronary Bypass Graft Stenosis
Interventions:   Drug: Ropivacaine;   Drug: sodium chloride 0.9%
Sponsor:   CMC Ambroise Paré
Completed

Near-infrared Spectroscopy Guided Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction

Conditions:   Myocardial Infarction;   Coronary Artery Disease;   Myocardial Ischemia;   Atherosclerosis;   Lipid-Rich Atherosclerosis of Coronary Artery;   Vascular Diseases;   Infarct Ischemia
Interventions:   Device: Near-infrared spectroscopy (NIRS);   Device: Angiography
Sponsor:   Odense University Hospital
Not yet recruiting

The Improving ATTENDance to Cardiac Rehabilitation Trial

Conditions:   Myocardial Infarction;   Heart Failure;   Heart Valve Diseases;   Cardiac Event;   Angina Pectoris;   Coronary Artery Disease
Interventions:   Behavioral: HYCR;   Behavioral: CBCR
Sponsors:   Henry Ford Health System;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Effect of Blood Group on the Survival Status of Intensive Care Patients

Conditions:   Critical Illness;   Nurse's Role;   Risk Factor;   Prognosis
Intervention:  
Sponsor:   Zonguldak Bulent Ecevit University
Recruiting

A Phase 2 Open Label Study to Assess the PK/PD Properties of RUC-4 in Patients With a ST-elevation Myocardial Infarction

Conditions:   Coronary Disease;   Myocardial Infarction;   Heart Diseases;   Vascular Diseases;   STEMI - ST Elevation Myocardial Infarction
Intervention:   Drug: RUC-4 Compound
Sponsors:   CeleCor Therapeutics;   ST. Antonius hospital Nieuwegein;   Diagram B.V.
Recruiting

Gamification to Increase Mobility in the Hospital

Conditions:   Coronary Artery Disease;   Coronary Heart Disease;   Hypertension;   Diabete Mellitus;   Dyslipidemias;   Obesity;   Heart Failure
Intervention:   Behavioral: Gamification Intervention
Sponsor:   University of Pennsylvania
Not yet recruiting

A Genomic Approach for Clopidogrel in Caribbean Hispanics

Conditions:   Cardiovascular Disease (CVD);   Stroke;   Acute Coronary Syndrome;   Peripheral Arterial Disease;   Coronary Artery Disease;   Myocardial Infarction
Interventions:   Genetic: CYP2C19 test;   Diagnostic Test: P2RY12 assay
Sponsors:   University of Puerto Rico;   National Institute on Minority Health and Health Disparities (NIMHD);   Icahn School of Medicine at Mount Sinai
Not yet recruiting

Study to Gather Information to What Extent Patients Follow the Treatment Regimen of Low-dose Aspirin for Primary and Secondary Prevention of Diseases of the Heart and Blood Vessels

Conditions:   Myocardial Infarction;   Stroke (Including Ischaemic Stroke and Transient Ischaemic Attack);   Unstable Angina;   Angina;   Ischaemic Heart Disease
Intervention:   Drug: Acetylsalicylic Acid (Aspirin, BAYE4465)
Sponsor:   Bayer
Active, not recruiting

New Heart Imaging Techniques to Evaluate Possible Heart Disease

Conditions:   Healthy;   Obesity;   Diabetes;   Arteriosclerosis;   Healthy Volunteers
Intervention:   Device: MR Imagining Techniques
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Post-authorization Safety Study on the Long Term Safety of Sonidegib in Patients With Locally Advanced Cell Carcinoma

Condition:   Basal Cell Carcinoma
Intervention:   Drug: sonidegib
Sponsor:   Sun Pharmaceutical Industries Limited
Recruiting

Nutritional Habits, and Coronavirus Disease 2019 (COVID-19) Outcome

Conditions:   Covid19;   Chronic Inflammation;   Non-Communicable Chronic Diseases
Intervention:  
Sponsor:   Cairo University
Recruiting

Cardiovascular Disease Screening

Conditions:   Congenital Heart Disease;   Atherosclerosis;   Myocardial Ischemia;   Myocardial Infarction;   Acquired Heart Disease
Interventions:   Device: Toshiba Aquilion ONE CT;   Device: SWiemens MRI scanner
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Suspended

Aclidinium Bromide Post-Authorisation Safety Study to Evaluate the Risk of Cardiovascular Endpoints

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Aclidinium bromide;   Drug: Other COPD medication
Sponsors:   AstraZeneca;   RTI Health Solutions
Recruiting

Technical Development of Cardiovascular Magnetic Resonance Imaging

Conditions:   Cardiomyopathy;   Congenital Heart Disease;   Cardiovascular Disease;   Cardiac Magnetic Resonance Imaging;   Acute Myocardial Infarction
Intervention:   Device: Siemens MRI scanner
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Suspended

The Evaluations of Cardiovascular Changes in Long-term Treated HIV-infected Individuals

Conditions:   HIV/AIDS;   Cardiovascular Diseases
Intervention:  
Sponsor:   Peking Union Medical College Hospital
Active, not recruiting

A Study Using the LMC Diabetes Registry to Learn More About Chronic Kidney Disease (CKD) in Canadian Patients With Type 2 Diabetes (T2D)

Condition:   Chronic Kidney Disease in Type 2 Diabetes
Intervention:   Drug: The physician's prescription in routine clinical practice
Sponsor:   Bayer
Not yet recruiting

Study to Evaluate the Effect on Parameters of Systemic Inflammation and Disease Outcomes and Safety of RPH-104 in Subjects With Acute ST-elevation Myocardial Infarction

Condition:   Acute ST Segment Elevation Myocardial Infarction
Interventions:   Biological: RPH-104 80 mg;   Drug: Placebo
Sponsors:   R-Pharm Overseas, Inc.;   Cromos Pharma, LLC;   DM 365, LLC;   Keystat, LLC
Not yet recruiting

Firazyr® Patient Registry (Icatibant Outcome Survey - IOS)

Condition:   Hereditary Angioedema (HAE)
Intervention:  
Sponsors:   Shire;   Takeda Development Center Americas, Inc.
Recruiting

Carnitine for the Treatment of Atherosclerosis.

Condition:   Metabolic Syndrome
Interventions:   Dietary Supplement: L-carnitine capsules;   Dietary Supplement: Cellulose capsules
Sponsors:   Dr. Amer Johri;   Heart and Stroke Foundation of Canada;   Queen's University
Completed

10-Years Follow-up of the EXAMINATION Trial

Conditions:   Myocardial Infarction;   ST Elevation Myocardial Infarction;   Infarction;   Necrosis;   Heart Disease;   Cardiovascular Diseases;   Vascular Diseases
Interventions:   Drug: Everolimus Eluting Coronary Stent System;   Device: Cobalt chromium balloon expandable stent (non-drug-eluting stent Arm)
Sponsor:   Hospital Clinic of Barcelona
Completed

Detection and Significance of Heart Injury in ST Elevation Myocardial Infarction.

Condition:   Acute ST-elevation Myocardial Infarction
Interventions:   Device: Coronary pressure wire;   Other: Magnetic resonance imaging of the heart
Sponsors:   NHS National Waiting Times Centre Board;   Siemens Healthcare Diagnostics Inc;   British Heart Foundation
Active, not recruiting

OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study

Condition:   Acute Coronary Syndrome
Intervention:   Device: PCI with implantation with DES
Sponsor:   Svelte Medical Systems, Inc.
Active, not recruiting

ACS Registry - A Non-interventional Study to Estimate the Rates of Outcomes in ACS Patients in Moscow

Conditions:   Heart Attack;   Stroke;   Cardiovascular Death
Intervention:  
Sponsor:   AstraZeneca
Recruiting

OPTIMIZE IDE for the Treatment of ACS

Condition:   Acute Coronary Syndrome
Intervention:   Device: DES
Sponsor:   Svelte Medical Systems, Inc.
Active, not recruiting

Randomized Evaluation of Decision Support Interventions for Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Other: Patient Decision Aid;   Other: Encounter Decision Aid
Sponsors:   University of Utah;   Mayo Clinic;   American Heart Association;   Patient-Centered Outcomes Research Institute
Not yet recruiting

A Pilot Proof of Concept, Randomized Controlled, Single-Center Study of a Decision Aid Tool for Older Patients Considering LHC as Treatment for NSTEMI

Condition:   NSTEMI
Intervention:   Behavioral: Shared Decision Aid
Sponsor:   NYU Langone Health
Enrolling by invitation

Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents

Conditions:   Traumatic Brain Injury;   Intracranial Hypertension
Interventions:   Drug: cisatracurium besilate;   Other: Placebo
Sponsor:   University Hospital, Clermont-Ferrand
Recruiting

The Assessment Of Myocardial Viability Based On CTA/MRI Hybrid Models

Conditions:   Acute Myocardial Infarction;   Myocardial Viability;   Vulnerable Coronary Plaques;   Coronary Stenosis;   Myocardial Fibrosis
Intervention:   Diagnostic Test: Speckle Tracking echocardiography
Sponsors:   Cardio Med Medical Center;   University of Targu Mures, Romania;   Tîrgu Mureș Emergency Clinical County Hospital, Romania
Recruiting

Multiomics and Imaging-based Assessment of Vulnerable Coronary Plaques in Acute Coronary Syndromes

Conditions:   Coronary Stenosis;   Acute Coronary Syndrome;   Acute Myocardial Infarction;   Atheromatous Plaques;   Atherosclerosis;   Unstable Angina;   Non-ST Elevation Myocardial Infarction
Intervention:   Diagnostic Test: cardiac imaging tests
Sponsor:   Cardio Med Medical Center
Recruiting

Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection

Conditions:   Coronary Aneurysm;   Dermatitis, Atopic;   Immune System Diseases;   STAT3 Transcription Factor;   Job Syndrome
Intervention:  
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Albert Einstein College of Medicine
Recruiting

Establish a Telecare Model of Acute Coronary Syndrome Patient With Heart Stent Implantation by a Non-invasive Wearable Device and Artificial Intelligence Cloud to Reducing Medical Adverse Events.

Conditions:   Acute Coronary Syndrome;   Percutaneous Transluminal Coronary Angioplasty
Intervention:   Device: use EKG Wisdom bracelet
Sponsors:   Taipei Medical University Shuang Ho Hospital;   Taipei Medical University WanFang Hospital;   Taipei Medical University Hospital;   Taipei Medical University;   Lotung Poh-Ai Hospital
Not yet recruiting

Acute Impact of the Impella CP Assist Device in Pts. With Cardiogenic Shock on the Patients Hemodynamic

Condition:   Cardiogenic Shock
Intervention:   Device: Impella CP microaxial pump
Sponsor:   University of Leipzig
Recruiting

Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Biological: Apolipoprotein A-I [human] (apoA-I);   Other: Placebo
Sponsor:   CSL Behring
Recruiting

SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19)

Conditions:   Covid-19;   SARS-CoV2;   Surgery;   Surgical Procedure; Complications, Late Effect of Complications;   Postoperative Complications
Intervention:  
Sponsors:   Centre hospitalier de l'Université de Montréal (CHUM);   Hôpital Maisonneuve-Rosemont;   Centre de recherche du Centre hospitalier universitaire de Sherbrooke;   Hopital du Sacre-Coeur de Montreal;   St. Justine's Hospital;   Institut de Cardiologie de Montréal;   McGill University Health Centre/Research Institute of the McGill University Health Centre;   CHU de Quebec-Universite Laval;   Institut universitaire de cardiologie et de pneumologie de Québec
Recruiting

Extended Care in High-Risk Surgical Patient (EXCARE) Pathway in High-risk Surgical Population

Conditions:   Postoperative Complications;   Patient Care Team
Interventions:   Behavioral: Postoperative Monitoring;   Diagnostic Test: High-sensitivity cardiac troponin testing
Sponsor:   Hospital de Clinicas de Porto Alegre
Recruiting

The Evaluation of Endothelial Function in the Diagnosis of Acute Coronary Syndrome (ACS)

Conditions:   Chest Pain;   Acute Coronary Syndrome
Intervention:   Device: Digital plethysmography in the diagnosis of Acute Coronary Syndrome
Sponsor:   University of Monastir
Recruiting

CorPath GRX STEMI Study (TREAT)

Conditions:   STEMI - ST Elevation Myocardial Infarction;   CAD
Intervention:   Procedure: Robotic-PCI (CorPath GRX System)
Sponsor:   Corindus Inc.
Not yet recruiting

The Next Leap in Cardiac Magnetic Resonance Imaging:Cycling the Field

Condition:   Myocardial Infarction
Interventions:   Procedure: Cardiac Magnetic Resonance Imaging;   Procedure: Fast Field Cycling - Magnetic Resonance Imaging;   Procedure: Electrocardiogram;   Procedure: Echocardiogram
Sponsor:   University of Aberdeen
Not yet recruiting

Acute Myocardial Infarction Study in Northeastern China

Condition:   Acute Myocardial Infarction
Intervention:   Procedure: thrombolysis
Sponsors:   Second Hospital of Jilin University;   Yanbian University Hospital;   Dunhua City Hospital in Jilin Province;   Liaoyuan City Central Hospital;   Dongliao People's Hospital;   Songyuan Central Hospital;   Changling People's Hospital;   Siping Central Hospital;   The First People's Hospital of Manchu Autonomous County;   Changchun Center Hospital;   Nongan People's Hospital;   Beihua University;   Jilin Hospital of Integrated Traditional Chinese and Western Medicine;   Panshi City Hospital;   Tonghua Central Hospital;   Baishan Central Hospital;   Jingyu People's Hospital;   Meihekou Central Hospital;   Baicheng Central Hospital;   Tongyu First Hospital
Recruiting

Stunning in Takotsubo Versus Acute Myocardial Infarction

Condition:   Myocardial Stunning
Interventions:   Diagnostic Test: Echocardigraphy (ECHO);   Diagnostic Test: Bloodtest
Sponsor:   Vastra Gotaland Region
Recruiting

Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack

Condition:   Acute Myocardial Infarction
Interventions:   Drug: BAY2433334;   Other: BAY2433334 matching placebo
Sponsor:   Bayer
Recruiting

Impact of Cardiac Rehabilitation Programs on Left Ventricular Remodeling After Acute Myocardial Infarction - the REHAB Trial

Conditions:   Acute Myocardial Infarction;   Non-ST Elevation Myocardial Infarction;   Systemic Inflammation;   Ventricular Remodeling;   Acute Coronary Syndrome
Interventions:   Diagnostic Test: Cardiac imaging;   Diagnostic Test: Laboratory analysis
Sponsors:   Cardio Med Medical Center;   University of Medicine and Pharmacy of Targu Mures;   University Hospital of Targu Mures, Romania
Recruiting

Efficacy, Safety and Tolerability of ATH3G10 in Patients With ST-elevation Myocardial Infarction

Condition:   ST Elevation Myocardial Infarction
Interventions:   Drug: ATH3G10;   Drug: Placebo
Sponsor:   Athera Biotechnologies AB
Active, not recruiting

Pan-Cardio-Genetics Clot Assessment in Acute Coronary Syndromes

Conditions:   STEMI - ST Elevation Myocardial Infarction;   Thrombi;   MicroRNA
Intervention:   Procedure: thrombus aspiration
Sponsors:   Aristotle University Of Thessaloniki;   HELLENIC CENTER FOR MARINE RESEARCH;   Harvard Medical School;   Centre for Research and Technology Hellas
Recruiting

Quantitative Estimation of Thrombus Burden in Patients With STEMI Using Micro-Computed Tomography (QUEST-STEMI)

Conditions:   ST Elevation Myocardial Infarction;   Thrombi
Intervention:  
Sponsors:   Aristotle University Of Thessaloniki;   Hellenic Centre for Marine Research;   Harvard Medical School;   MHAT Hadji Dimitar Hospital, Sliven, Bulgaria
Completed

Milrinone Versus Dobutamine in Critically Ill Patients

Conditions:   Low Cardiac Output Syndrome;   Cardiogenic Shock;   Acute Coronary Syndrome;   Pulmonary Edema
Interventions:   Drug: Milrinone;   Drug: Dobutamine
Sponsor:   Ottawa Heart Institute Research Corporation
Completed

Cangrelor in ST-Elevation Myocardial Infarction to Decrease Infarct Size

Condition:   STEMI - ST Elevation Myocardial Infarction
Intervention:   Drug: Cangrelor
Sponsor:   Khaled Ziada, MD
Terminated

Downstream Versus Upstream Strategy for the Administration of P2Y12 Receptor Blockers

Condition:   Unstable Angina or Non ST Elevated Myocardial Infarction
Interventions:   Procedure: Downstream strategy;   Procedure: Upstream strategy
Sponsors:   University of Padova;   Azienda Ospedaliera di Padova
Recruiting

Cardiogenic Shock Integrated PHenotyping for Event Reduction

Condition:   Heart Failure
Intervention:   Diagnostic Test: ELISA
Sponsor:   Niguarda Hospital
Recruiting

Biomarkers of Acute Stroke in Clinic

Conditions:   Ischemic Stroke;   Ischemia;   Atrial Fibrillation;   Transient Ischemic Attack;   Transient Cerebrovascular Events;   Thrombotic Stroke;   Stroke;   Stroke, Acute;   Stroke, Ischemic;   Stroke, Complication;   Stroke of Basilar Artery;   Atherosclerosis;   Atheroma;   Cardioembolic Stroke;   Cardiomyopathies;   Cardiovascular Stroke;   Thromboembolism
Intervention:   Diagnostic Test: ISCDX blood test
Sponsor:   Ischemia Care LLC
Recruiting

PRediction of Acute Coronary Syndrome in Acute Ischemic StrokE

Conditions:   Stroke, Ischemic;   Acute Coronary Syndrome
Intervention:   Diagnostic Test: Coronary angiography
Sponsors:   Charite University, Berlin, Germany;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK);   German Center for Neurodegenerative Diseases (DZNE)
Recruiting

Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity

Conditions:   Obesity;   Metabolic Syndrome X
Interventions:   Drug: Metformin;   Drug: Orlistat;   Drug: Topiramate;   Drug: Placebo
Sponsor:   University of Iowa
Terminated

Complex Multiple Risk Behavior Intervention in People Between 45 to 75 Years (EIRA Study)

Conditions:   Health Behavior;   Health Promotion;   Primary Health Care;   Implementation Research;   Smoking Cessation;   Mediterranean Diet;   Physical Activity
Intervention:   Behavioral: EIRA intervention
Sponsors:   Jordi Gol i Gurina Foundation;   Instituto de Salud Carlos III;   Department of Health, Generalitat de Catalunya;   Parc Sanitari Sant Joan de Déu;   Sanidad de Castilla y León;   Servei de Salut de les Illes Balears;   Institut Català de la Salut;   Servicio Aragonés de Salud;   Osakidetza;   Andaluz Health Service;   Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud;   Servicio Galego de Saúde (SERGAS)
Completed