Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

HeartHab, Can a Patient-tailored Application Support Coronary Artery Disease Patients During Rehabilitation?

Condition:   Coronary Artery Disease
Intervention:   Behavioral: HeartHab application intervention
Sponsor:   Hasselt University
Not yet recruiting - verified January 2016

The Effect of Resistance Training on Proprotein Subtilisin Convertase Kexin 9 Level After Coronary Bypass Surgery

Condition:   Coronary Artery Disease
Interventions:   Behavioral: resistance training;   Behavioral: aerobic training
Sponsor:   National Cardiovascular Center Harapan Kita Hospital Indonesia
Not yet recruiting - verified February 2016

Remote Ischemic Preconditioning to Prevent Contrast Nephropathy

Condition:   Acute Kidney Injury
Intervention:   Procedure: Remote ischemic preconditioning
Sponsor:   Johns Hopkins University
Recruiting - verified February 2016

Danlou Tablets to Prevent Left Ventricular Remodeling

Conditions:   Left Ventricular Remodeling;   Acute Myocardial Infarction
Interventions:   Drug: Danlou Tablets;   Other: Placebo
Sponsor:   shuai Mao
Completed - verified February 2016

Does Co-registration of OCT and Angiography Reduce Geographic Miss of Stent Implantation?

Condition:   Coronary Artery Disease
Interventions:   Procedure: Coronary PCI with OCT with Co Registration;   Procedure: Coronary PCI with OCT without Co Registration
Sponsors:   St. Francis Hospital, New York;   CardioVascular Research Foundation, Korea
Recruiting - verified February 2016

Stem Cell Therapy in IschEmic Non-treatable Cardiac Disease

Condition:   Heart Failure
Intervention:   Biological: CSCC_ASC
Sponsors:   JKastrup;   European Union
Not yet recruiting - verified February 2016

Prospective Evaluation of Prognosis of Pci Patients Using Network Data in SHengjing Hospital

Condition:   Coronary Heart Disease
Intervention:   Procedure: PCI
Sponsor:   Shengjing Hospital
Not yet recruiting - verified January 2016

Safety and Exploratory Efficacy Study of UCMSCs in Patients With Ischemic Heart Disease (SEESUPIHD)

Conditions:   Acute Myocardial Infarction;   Myocardial Infarction;   Ischemic Cardiomyopathy
Intervention:   Biological: umbilical cord mesenchymal stem cells
Sponsors:   South China Research Center for Stem Cell and Regenerative Medicine;   Sun Yat-sen University
Not yet recruiting - verified January 2016

A Randomized, Pharmacodynamic Comparison of Low Dose Ticagrelor to Clopidogrel in Patients With Prior Myocardial Infarction

Conditions:   Myocardial Infarction;   Diabetes Mellitus;   Renal Disease;   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsors:   University of Patras;   AstraZeneca
Not yet recruiting - verified January 2016

Accelerated Rule Out of Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Procedure: Accelerated, combined biomarker rule-out strategy for MI
Sponsor:   Aarhus University Hospital Skejby
Recruiting - verified February 2016

Retrospective Evaluation of Prognosis of Pci Patients Using Network Data in SHengjing Hospital

Condition:   Coronary Heart Disease
Intervention:   Procedure: PCI
Sponsor:   Shengjing Hospital
Recruiting - verified January 2016

A Study of Allogeneic Low Oxygen Mesenchymal Bone Marrow Cells in Subjects With Myocardial Infarction

Conditions:   Myocardial Infarction With/Without ST Segment Elevation;   Allogeneic Low Oxygen Mesenchymal Bone Marrow Cells
Interventions:   Biological: Stem cells;   Other: Placebo
Sponsor:   Altaco XXI, LLP
Recruiting - verified February 2016

Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients With InteRmediate Stenosis

Condition:   Stable Angina
Intervention:   Device: Drug-eluting stent
Sponsors:   Seoul National University Hospital;   Ajou University School of Medicine;   Keimyung University Dongsan Medical Center;   Inje University
Not yet recruiting - verified February 2016

Clinical Research to Explore Manifestations of Heart Failure Using Infrared Thermal Imaging Technology

Condition:   Heart Failure,Congestive
Intervention:  
Sponsor:   Jing Huang
Recruiting - verified February 2016

Distal Renal Denervation

Condition:   Hypertension, Resistant to Conventional Therapy
Interventions:   Procedure: Distal renal denervation;   Procedure: Conventional renal denervation
Sponsor:   Federal State Budgetary Scientific Institution, Research Institute of Cardiology
Active, not recruiting - verified January 2016

Echocardiography, Adherence to Mediterranean Diet (AMDS) and Physical Exercise in Fatty Liver

Condition:   Fatty Liver
Intervention:  
Sponsor:   Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Completed - verified January 2016

Fractional Flow Reserve Versus Angiography for Guiding Selective Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction

Conditions:   Fractional Flow Reserve;   ST-segment Elevation Myocardial Infarction;   Percutaneous Coronary Intervention
Intervention:  
Sponsor:   Nanjing Medical University
Not yet recruiting - verified January 2016

Rivaroxaban ACS Specialist Cohort Event Monitoring Study

Condition:   Acute Coronary Syndrome
Intervention:   Other: This is a non-interventional study
Sponsor:   Drug Safety Research Unit, Southampton, UK
Recruiting - verified February 2016

EXpanded CELL ENdocardiac Transplantation (EXCELLENT)

Condition:   Acute Myocardial Infarction
Interventions:   Drug: PROTHERACYTES;   Device: Standard of Care (Percutaneous Transluminal Coronary Angioplasty and stent(s) implantation)
Sponsor:   CellProthera
Recruiting - verified February 2016

Electrical Stimulation Improves Exercise Tolerance in Patients With Advanced Heart Failure on Continuous Dobutamine Use

Conditions:   Heart Failure;   Ventricular Dysfunction, Left
Interventions:   Device: Neuromuscular Electrical Stimulator;   Other: Physical Therapy Session
Sponsor:   Federal University of São Paulo
Completed - verified January 2016

Influence of Severe Heart Failure to Function and Molecular Biological Parameters of Catabolism in the Human Diaphragm and Peripheral Skeletal Muscle

Conditions:   Heart Failure;   Ischemic Myocardiopathy;   Dilatative Myocardiopathy
Interventions:   Other: Biopsy of the diaphragmatic muscle;   Other: Skeletal muscle biopsy
Sponsor:   Norman Mangner
Recruiting - verified January 2016

Sevoflurane and Percutaneous Coronary Intervention by Stent

Condition:   Myocardial Infarction
Intervention:   Drug: sevoflurane
Sponsor:   Instituto Dante Pazzanese de Cardiologia
Not yet recruiting - verified January 2016

Hypothermia as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction

Conditions:   Hypothermia, Induced;   Rewarming;   Myocardial Infarction;   Percutaneous Cornonary Intervention
Interventions:   Device: Proteus® Cooling System;   Procedure: Primary Percutaneous Coronary Intervention
Sponsors:   University of Sao Paulo General Hospital;   ZOLL Circulation, Inc., USA
Recruiting - verified January 2016

Remote Ischaemic Conditioning and Coronary Endothelial Function (RIC-COR)

Conditions:   Ischemic Preconditioning;   Coronary Disease
Interventions:   Procedure: Remote ischaemic conditioning;   Procedure: Arm cuff placement, no inflation;
Sponsors:   NHS National Waiting Times Centre Board;   University of Glasgow
Enrolling by invitation - verified January 2016

Knowledge Translation for Patients With Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Intervention:   Behavioral: knowledge translation
Sponsors:   Montreal General Hospital;   Sanofi;   Canadian Institutes of Health Research (CIHR);   Fonds de la Recherche en Santé du Québec
Completed - verified January 2016

Comparative Effectiveness of Health System vs. Multilevel Interventions to Reduce Hypertension Disparities

Condition:   Uncontrolled Hypertension
Interventions:   Behavioral: Provider Audit-Feedback;   Behavioral: Provider Audit-Feedback, Stratified by race, ethnicity, payor status;   Behavioral: Blood Pressure Measurement Standardization;   Behavioral: System Level Leadership Intervention;   Behavioral: Collaborative Care Team Intervention;   Behavioral: Community Health Worker;   Behavioral: Specialist Care
Sponsors:   Johns Hopkins University;   National Heart, Lung, and Blood Institute (NHLBI);   Mid-Atlantic Association of Community Health Centers;   Patient-Centered Outcomes Research Institute
Not yet recruiting - verified February 2016

Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor

Condition:   Acute Coronary Syndrome
Interventions:   Procedure: Early CABG (Day 2-3 after ticagrelor discontinuation);   Procedure: Delayed CABG (Day 5-7 after ticagrelor discontinuation)
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR)
Not yet recruiting - verified January 2016

Short-term Air Pollution Exposure and In-hospital Outcomes in Patients With Acute Myocardial Infraction

Conditions:   Air Pollution;   Acute Myocardial Infarction;   Percutaneous Coronary Intervention
Intervention:  
Sponsors:   Nanjing Medical University;   The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Recruiting - verified January 2016

GLP-1 and Hyperoxia for Organ Protection in Heart Surgery

Conditions:   Coronary Disease;   Shock, Cardiogenic;   Renal Failure;   Stroke;   Brain Injury;   Aortic Valve Disease
Interventions:   Drug: Byetta (Lilly, Exenatide);   Drug: Conoxia (AGA, oxygen);   Drug: 20% Human Albumin
Sponsor:   Rigshospitalet, Denmark
Not yet recruiting - verified February 2016

Hydroxychloroquine in Acute Coronary Syndrome: Prevention of Recurrent Cardiovascular Events

Conditions:   Myocardial Infarction;   Acute Coronary Syndrome;   Inflammation;   Hydroxychloroquine;   Antirheumatic Agents;   Cardiovascular Diseases;   Angina, Unstable
Interventions:   Drug: Hydroxychloroquine;   Drug: Placebo
Sponsors:   Helsinki University Central Hospital;   Finnish Foundation for Cardiovascular Research;   Orion Corporation, Orion Pharma
Not yet recruiting - verified February 2016

Study of the Impact of Cheese Matrix on Postprandial Lipemia: a Clinical Study

Condition:   Healthy
Interventions:   Other: Test meal (butter);   Other: Test meal (cheddar cheese);   Other: Test meal (cream cheese)
Sponsor:   Laval University
Not yet recruiting - verified January 2016

Clinical Performance Evaluation of AQT90 FLEX TnI and TnT

Condition:   Myocardial Infarction
Intervention:  
Sponsor:   Radiometer Medical ApS
Recruiting - verified January 2016

Vericiguat Drug-drug Interaction With Nitroglycerin in Stable Coronary Artery Disease Patients

Condition:   Coronary Artery Disease
Interventions:   Drug: Vericiguat (BAY1021189);   Drug: Placebo;   Drug: Nitroglycerin
Sponsors:   Bayer;   Merck Sharp & Dohme Corp.
Recruiting - verified January 2016

EVOLVE Short DAPT Study

Condition:   Coronary Artery Disease
Interventions:   Drug: 3 months of dual antiplatelet therapy (DAPT);   Device: SYNERGY Stent System
Sponsor:   Boston Scientific Corporation
Recruiting - verified January 2016

EValuation of the Impact of a TOpical Lotion on Permanent Chemotherapy Induced Hair Disorders in Cancer Survivors

Condition:   Alopecia
Interventions:   Other: CG428;   Other: Placebo
Sponsors:   Samsung Medical Center;   Legacy Healthcare Services
Recruiting - verified January 2016

Exercise Training in Patients With Atrial Fibrillation (OPPORTUNITY Study)

Condition:   Atrial Fibrillation
Interventions:   Behavioral: moderate-intensity continuous exercise training;   Behavioral: high-intensity interval training
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting - verified November 2015

Randomized Trial of COBRA PzF Stenting to Reduce Duration of Triple Therapy

Conditions:   Angina, Stable;   Angina, Unstable;   Anticoagulants
Interventions:   Device: COBRA PzF;   Device: DES
Sponsor:   CeloNova BioSciences, Inc.
Recruiting - verified February 2016

Assessment of Catheter-based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement

Condition:   Coronary Artery Disease
Interventions:   Device: RXi System;   Device: Pressure Wire
Sponsor:   Acist Medical Systems
Recruiting - verified November 2015

The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment

Conditions:   Homocysteine;   Coronary Disease;   Angioplasty,Balloon,Coronary;   Contrast Media;   Nephropathy;   Hypertension
Interventions:   Drug: Enalapril Maleate Tablets(as the program-based antihypertension);   Drug: Enalapril Maleate and Folic Acid tablets(as the program-based antihypertension);   Drug: Placebo
Sponsor:   Fuling Central Hospital of Chongqing City
Recruiting - verified February 2016

Predischarge Bundle to Minimize Negative Impact on Quality of Life of Nuisance Bleedings

Conditions:   Myocardial Ischemia;   Hemorrhage;   Quality of Life;   Platelet Aggregation Inhibitors
Interventions:   Behavioral: good clinical practice;   Behavioral: bundle group
Sponsor:   University Hospital of Ferrara
Recruiting - verified January 2016

Coronary Artery Aneurysm Registry

Condition:   Coronary Artery Aneurysm
Intervention:  
Sponsor:   St Carlos Hospital, Madrid, Spain
Recruiting - verified September 2015

Optilene® Suture for Coronary Artery Bypass Graft Surgery

Conditions:   Coronary Heart Disease;   Multi Vessel Coronary Artery Disease
Intervention:   Procedure: Coronary Artery Bypass Graft surgery
Sponsors:   Aesculap AG;   B.Braun Surgical SA
Recruiting - verified January 2016

ComparisoN of ticAgrelor vs. Clopidogrel in endoTHeliAl Function of COPD patieNts

Conditions:   Coronary Artery Disease;   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Aspirin 100 mg;   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   University Hospital of Ferrara
Recruiting - verified January 2016

Evaluating Increasing Physical Activity After Hospitalization for Acute Coronary Syndrome

Conditions:   Physical Activity;   Acute Coronary Syndrome
Interventions:   Behavioral: Financial incentive;   Behavioral: Daily feedback
Sponsor:   University of Pennsylvania
Not yet recruiting - verified January 2016

Reverse the HYpoTHyroid Status in Acute Myocardial InfarCtion (RHYTHMIC)

Conditions:   Myocardial Infarction;   Hypothyroidism
Intervention:   Drug: Levothyroxine
Sponsors:   Chinese Academy of Medical Sciences, Fuwai Hospital;   Beijing Municipal Science & Technology Commission;   Peking Union Medical College Hospital;   Peking University Third Hospital;   Beijing Anzhen Hospital;   Beijing Chao Yang Hospital;   Beijing Friendship Hospital;   The Luhe Teaching Hospital of the Capital Medical University
Recruiting - verified August 2015

Coronary Disease and the Effect of High-intensity Interval Training

Condition:   Coronary Disease
Interventions:   Behavioral: high intensity interval-based aerobic exercise;   Other: Usual care
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital
Recruiting - verified February 2016

Colesevelam, Lipids And Sugars, South Asian Canadian Trial

Condition:   Dyslipidemia
Intervention:  
Sponsors:   Canadian Cardiovascular Research Network;   Valeant Canada Limited
Recruiting - verified January 2016

RIGENERA 2.0 Trial

Conditions:   Anterior Myocardial Infarction;   Heart Failure
Interventions:   Drug: rhu G-CSF;   Drug: optimal standard of care;   Procedure: Myocardial Contrast Echocardiography
Sponsor:   Catholic University of the Sacred Heart
Recruiting - verified January 2016

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Recruiting - verified January 2016

Vortioxetine in Patients With Major Depressive Disorder and Coronary Artery Disease

Conditions:   Major Depressive Disorder;   Coronary Artery Disease
Intervention:   Drug: Vortioxetine
Sponsors:   Thomas Jefferson University;   Takeda
Not yet recruiting - verified February 2016

Acute Vascular Response to Exercise in Women With Nonobstructive Coronary Artery Disease

Condition:   Nonobstructive Coronary Artery Disease
Intervention:   Other: Slow-paced walking
Sponsor:   University of Florida
Recruiting - verified February 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified February 2016

IMproving reModeling in Acute myoCardial Infarction Using Live and Asynchronous TElemedicine.

Conditions:   Left Ventricular Remodeling;   Medication Adherence;   Acute Coronary Syndrome
Intervention:   Other: Telemedicine
Sponsors:   National University Heart Centre, Singapore;   National University, Singapore;   National University Hospital, Singapore;   Tan Tock Seng Hospital
Recruiting - verified January 2016

Metformin and Corus CAD

Condition:   Coronary Artery Disease
Intervention:   Other: Corus CAD
Sponsor:   CardioDx
Completed - verified January 2016

Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery

Condition:   Coronary Artery Disease
Interventions:   Drug: Sitagliptin;   Drug: Placebo;   Drug: Regular Human Insulin;   Drug: Insulin glargine;   Drug: Supplemental insulin (Insulin lispro);   Drug: Supplemental insulin (Insulin aspart)
Sponsor:   Emory University
Recruiting - verified January 2016

Verapamil vs Heparin in Transradial Procedures

Condition:   Heart Disease, Ischemic
Interventions:   Drug: Heparin;   Drug: Verapamil
Sponsor:   University Hospital of Ferrara
Recruiting - verified January 2016

Prospective Registry of Acute Coronary Syndromes in Ferrara

Condition:   Acute Coronary Syndromes
Intervention:   Other: prospective collection of data and follow-up
Sponsor:   University Hospital of Ferrara
Recruiting - verified January 2016

Evaluation on the Safety of Ticagrelor Among Chinese ACS Patients

Condition:   Acute Coronary Syndrome (ACS)
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified February 2016

A Study to Obtain Additional Information on the Use of CorMatrix® CanGaroo ECM® Envelope

Condition:   Coronary Disease
Intervention:   Device: CorMatrix CanGaroo ECM Envelope
Sponsor:   CorMatrix
Withdrawn - verified January 2016

COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Exenatide;   Other: Remote Ischemic Conditioning (RIC);   Drug: Placebo
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Not yet recruiting - verified January 2016

An Observational Prospective Study to Understand the Usage Pattern of Ticagrelor With ACS (Acute Coronary Syndrome)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified February 2016

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study

Condition:   Cost Sharing, Acute Coronary Syndrome,
Intervention:   Other: Study voucher card
Sponsors:   AstraZeneca;   Duke Clinical Research Institute
Recruiting - verified January 2016

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Harvard Clinical Research Institute;   Medstar Research Institute
Recruiting - verified February 2016

Brilinta Taiwan Post Approval Safety Study

Condition:   Non ST-elevation Myocardial Infarction
Intervention:   Drug: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Sponsor:   AstraZeneca
Recruiting - verified February 2016

Frailty in Elderly Patients Receiving Cardiac Interventional Procedures

Condition:   Frailty
Intervention:   Other: frailty evaluation
Sponsor:   University Hospital of Ferrara
Recruiting - verified September 2015

PCA062 in pCAD-positive Tumors

Condition:   Triple Negative Breast Cancer, Head & Neck Cancer, Esophageal Cancer
Intervention:   Drug: PCA062
Sponsor:   Novartis Pharmaceuticals
Recruiting - verified January 2016

Prevention of Myocardial Injury in Non-cardiac Surgery

Conditions:   Myocardial Injury;   Myocardial Infarction
Intervention:   Procedure: Remote ischemic preconditioning
Sponsor:   University Hospital Koge
Recruiting - verified February 2016

CSCC_ASC Therapy in Patients With Severe Heart Failure

Condition:   Heart Failure
Intervention:   Biological: Allogeneic adipose derived stem cells (CSCC_ASC)
Sponsor:   JKastrup
Completed - verified February 2016

Long-term Exercise in Older Cardiac Patients

Condition:   Coronary Artery Disease
Interventions:   Behavioral: SystemCHANGE;   Behavioral: CHANGE+;   Behavioral: Usual Care
Sponsor:   Case Western Reserve University
Completed - verified January 2016

Screening for Chronic Obstructive Pulmonary Disease in Patients With Acute Coronary Syndromes

Conditions:   Chronic Obstructive Pulmonary Disease;   Acute Coronary Syndromes
Intervention:   Other: screening test
Sponsor:   University Hospital of Ferrara
Active, not recruiting - verified September 2015

Italian Absorb Registry

Condition:   Coronary Artery Disease
Intervention:   Device: PCI with Absorb scaffold
Sponsors:   Ospedale Santa Croce-Carle Cuneo;   Fatebenefratelli and Ophthalmic Hospital;   Bolognini Hospital;   Ospedale Regionale di Aosta;   Ospedali Riuniti di Ancona;   S. Giacomo Hospital;   Azienda U.L.S.S n.9 Ospedale di Treviso Ca Foncello;   Ospedale San Bortolo di Vicenza;   Azienda Ospedaliera Brotzu;   San Giuseppe Moscati Hospital;   Azienda Sanitaria Locale USL 13 Ospedale Mazzoni di Ascoli Piceno;   S. Andrea Hospital;   Ospedale Monaldi di Napoli;   Azienda Ospedaliera di Padova;   Ospedale della Misericordia di Grosseto;   Ospedale Santa Corona di Pietra Ligure;   Istituto di Ricerche Farmacologiche Mario Negri Milano
Active, not recruiting - verified February 2016

Long-term Follow-up of antithrombotIc Management Patterns in Acute Coronary Syndrome Patients in Asia-China Extension

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified January 2016

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified January 2016

Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers

Conditions:   Acute Myocardial Infarction (AMI);   Acute Coronary Syndrome (ACS);   ST Elevation (STEMI) Myocardial Infarction;   Ischemic Reperfusion Injury;   Non-ST Elevation (NSTEMI) Myocardial Infarction;   Angina, Unstable
Intervention:   Drug: Oxygen
Sponsors:   Karolinska Institutet;   University Hospital, Linkoeping
Active, not recruiting - verified January 2016

A Clinical Trial on the Candidate Vaccine cAd3-EBOZ in Healthy Adults in Switzerland

Condition:   Ebola Vaccines
Interventions:   Biological: cAd3-EBOZ vaccine;   Biological: Placebo (for cAd3-EBOZ vaccine)
Sponsors:   Centre Hospitalier Universitaire Vaudois;   Infectious Disease Service, CHUV, Lausanne;   Policlinique Médicale Universitaire;   Clinical Trial Unit, Lausanne University Hospital;   Swiss Tropical & Public Health Institute;   University of Lausanne;   GlaxoSmithKline;   World Health Organization;   Immunology and Allergy Service, CHUV, Lausanne
Completed - verified January 2016

Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers

Conditions:   Myocardial Infarction;   Inflammation;   Acute Coronary Syndrome (ACS);   Reperfusion Injury
Interventions:   Biological: Salmonella typhi vaccine (Typhim Vi®);   Drug: Oxygen (Oxymask®);   Drug: Atorvastatin
Sponsors:   Karolinska Institutet;   University Hospital, Linkoeping
Active, not recruiting - verified January 2016

A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction

Conditions:   Heart Attack;   NSTEMI
Interventions:   Biological: AMI MultiStem cells;   Other: Sham
Sponsors:   Athersys, Inc;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 2016

Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Condition:   Hypercholesterolemia
Intervention:   Biological: Evolocumab
Sponsor:   Amgen
Enrolling by invitation - verified February 2016

Infliximab for Kawasaki Disease Patients Resistant to IVIG : a Multicentre, Prospective, Randomised Trial

Condition:   Kawasaki Disease
Interventions:   Drug: Infliximab;   Drug: IVIG
Sponsors:   Fudan University;   Shanghai Children's Medical Center;   Shanghai 10th People's Hospital;   Shanghai Eighth People's Hospital;   Shanghai Xuhui Distrct Center Hospital
Completed - verified December 2014

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified January 2016

Peripheral Arterial Insufficiency Associated With HIV/AIDS

Conditions:   Arterial Insufficiency;   Acquired Immunodeficiency Syndrome;   HIV
Intervention:   Procedure: Ankle-Brachial index
Sponsor:   Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Completed - verified January 2016

Exercise as a Life-long Medicine in Patients With Coronary Artery Disease

Conditions:   Cardiovascular Diseases;   Myocardial Infarction;   Angina (Stable)
Interventions:   Behavioral: high-intensity exercise training;   Behavioral: web-based follow-up program;   Behavioral: usual care
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital;   Levanger Hospital
Recruiting - verified February 2016

Off Pump Versus On Pump Coronary Artery Bypass Grafting in Frailty Patients (FRAGILE)

Conditions:   Coronary Artery Disease;   Complications Due to Coronary Artery Bypass Graft;   Fragility
Interventions:   Procedure: OPCAB;   Procedure: CABG
Sponsors:   University of Sao Paulo General Hospital;   InCor Heart Institute;   Cardiac Emergency Hospital of Pernambuco;   Alberto Urquiza Wanderley Hospital of João Pessoa;   Pitangueiras Hospital of Jundiaí;   University of Campinas, Brazil;   Cardiology Institute of the Distrito Federal;   National Cardiology Institute;   Federal University of São Paulo;   Pontifícia Universidade Católica do Paraná;   Clinical Hospital Samuel Libânio of Pouso Alegre;   Beneficência Portuguesa of São Paulo;   Pontifical University Catholic of Campinas;   InCor Heart Institute of Natal
Not yet recruiting - verified January 2016

New Technologies to Determine Carotid Plaque Vulnerability

Conditions:   Atherosclerosis;   Carotid Artery Plaque
Intervention:  
Sponsors:   Mayo Clinic;   GE Healthcare
Recruiting - verified January 2016

Multidetector Coronary CT In Vasospastic Angina

Condition:   Vasospastic Angina
Interventions:   Procedure: Positive CAG with EG test;   Procedure: Negative CAG with EG test
Sponsor:   Dong-A University
Recruiting - verified February 2016

Paraoxonase and HDL Qualities in Glycaemia and Inflammation

Conditions:   Diabetes.;   Bariatric Surgery.
Intervention:  
Sponsors:   Central Manchester University Hospitals NHS Foundation Trust;   British Heart Foundation;   Juvenile Diabetes Research Foundation
Recruiting - verified January 2016

Arrhythmia Prediction Trial

Conditions:   Myocardial Infarction;   Dilated Cardiomyopathy;   Heart Failure
Intervention:  
Sponsor:   University of Athens
Recruiting - verified January 2016

Remote Ischemic Preconditioning With Postconditioning in Heart Transplantation Surgery

Conditions:   Myocardial Ischemic Reperfusion Injury;   End Stage Heart Disease;   Heart Failure;   Cardiomyopathy
Interventions:   Procedure: RIPC+RIPostC;   Procedure: control
Sponsor:   Chinese Academy of Medical Sciences, Fuwai Hospital
Recruiting - verified February 2016

TEAMS (Troponin Elevation After Major Surgery) Study

Conditions:   Perioperative Myocardial Infarction;   Disability
Intervention:  
Sponsor:   University Health Network, Toronto
Active, not recruiting - verified November 2015

Trial of Dialysate Sodium in Chronic Hospitalized Hemodialysis Patients

Condition:   Intra-dialytic Hypotension
Interventions:   Drug: Lower dialysate sodium (138 mmol/L; using Renasol hemodialysis concentrate);   Drug: Higher dialysate sodium (142 mmol/L; using Renasol hemodialysis concentrate)
Sponsor:   Brigham and Women's Hospital
Recruiting - verified February 2016

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Losmapimod 7.5 mg twice daily;   Drug: Placebo twice daily
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Recruiting - verified January 2016

Effects of Intracoronary Prourokinase on the Coronary Flow During Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction

Conditions:   Myocardial Infarction;   Percutaneous Coronary Intervention;   Thrombolytic Therapy
Interventions:   Drug: Prourokinase;   Drug: Tirofiban;   Drug: normal saline
Sponsor:   Fudan University
Recruiting - verified February 2016

The Short- and Long Term Outcomes of Early Routine PCI With the Standard Treatment in Low-intermediate Risk ST-elevation Myocardial Infarction Patients Who Successfully Fibrinolysis.

Condition:   ST-elevation Myocardial Infarction
Intervention:   Other: Percutaneous coronary intervention
Sponsor:   Chiang Mai University
Completed - verified May 2014

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL112;   Biological: Placebo
Sponsor:   CSL Behring
Active, not recruiting - verified February 2016

Safety and Efficacy Study of Cilostazol to Treat Vasospastic Angina

Condition:   Vasospastic Angina
Intervention:   Drug: Cilostazol
Sponsor:   Korea Otsuka Pharmaceutical Co.,Ltd.
Completed - verified January 2016

Aortic Valve and Root Measurements Under Real-Time 3-Dimensional Visualization During Angiography

Conditions:   Coronary Artery Disease;   Aortic Stenosis
Intervention:   Radiation: Real-time 3-dimensional DynaCT
Sponsor:   Binita Shah
Recruiting - verified January 2016

Prognostic Impact of Sleep Apnea on Cardiovascular Morbidity and Mortality, in End Stage Renal Disease Patients

Conditions:   Obstructive Sleep Apnea;   End Stage Renal Disease
Interventions:   Other: No Sleep Apnea;   Other: Sleep Apnea - untreated;   Device: Sleep Apnea - treated
Sponsor:   Centre Hospitalier Universitaire Vaudois
Recruiting - verified January 2016

Phase III Study Comparing Two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N Versus Custodiol

Conditions:   Aortic Valve Disease;   Coronary Artery Disease (CAD)
Interventions:   Drug: Custodiol-N;   Drug: Custodiol
Sponsor:   Dr. F. Köhler Chemie GmbH
Recruiting - verified January 2016

Biomarkers and Antithrombotic Treatment in Cervical Artery Dissection - TREAT-CAD

Condition:   Cervical Artery Dissection
Interventions:   Drug: Acetylsalicylic acid;   Drug: vitamin K-antagonist
Sponsors:   University Hospital, Basel, Switzerland;   University Hospital Inselspital, Berne;   University of Lausanne Hospitals
Recruiting - verified February 2016

Ventricular Remodeling and Heart Failure After Myocardial Infarction: A Community Study

Conditions:   Heart Failure;   Myocardial Infarction
Intervention:  
Sponsor:   Mayo Clinic
Recruiting - verified February 2016

Efficacy Study of Glucagonlike Peptide-1 to Treat Reperfusion Injury

Condition:   Acute Myocardial Infarction
Interventions:   Drug: liraglutide (Novo Nordisk, Bagsværd, Denmark);   Drug: liraglutide placebo (Novo Nordisk)
Sponsor:   Chen Wei Ren, MD
Recruiting - verified February 2016

Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer

Conditions:   Breast Cancer;   Breast Tumors;   Cancer of Breast
Interventions:   Drug: Metformin;   Drug: Atorvastatin;   Procedure: Breast surgery
Sponsor:   Columbia University
Recruiting - verified February 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified January 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified January 2016

Post-Market CorPath Registry on the CorPath 200 System in Percutaneous Coronary Interventions

Conditions:   Coronary Artery Disease;   Coronary Disease;   Myocardial Ischemia;   Heart Diseases;   Cardiovascular Diseases;   Arteriosclerosis;   Arterial Occlusive Diseases;   Vascular Diseases
Intervention:   Procedure: CorPath-assisted Percutaneous Coronary Intervention
Sponsor:   Corindus Inc.
Recruiting - verified January 2016

A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ ABSORB CHINA Randomized Controlled Trial (RCT)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: XIENCE V EECSS;   Device: ABSORB BVS System
Sponsor:   Abbott Vascular
Active, not recruiting - verified January 2016

Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Active, not recruiting - verified February 2016

Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Recruiting - verified February 2016

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified January 2016

OPtical Frequency Domain Imaging Versus INtravascular Ultrasound in Percutaneous Coronary InterventiON - OPINION Imaging

Condition:   Coronary Artery Disease
Interventions:   Device: OFDI-guided PCI & IVUS;   Device: IVUS-guided PCI & OFDI
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Wakayama Medical University
Active, not recruiting - verified February 2016

China Acute Myocardial Infarction Registry

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Chinese Academy of Medical Sciences, Fuwai Hospital
Recruiting - verified January 2016

RAdiation Dose In percutAneuos Coronary Procedures Through TransradIal apprOach Using Dedicated radiatioN Shields

Condition:   Myocardial Ischemia
Interventions:   Procedure: Coronary angiography;   Procedure: PCI;   Procedure: Right approach;   Procedure: Left approach
Sponsor:   Ospedale Sandro Pertini, Roma
Completed - verified January 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified February 2016

An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction

Conditions:   Acute Coronary Syndrome;   Non-ST Elevation (NSTEMI) Myocardial Infarction;   Acute ST Segment Elevation Myocardial Infarction;   Angina, Unstable
Intervention:   Drug: Oxygen
Sponsors:   Karolinska Institutet;   Swedish Heart Lung Foundation;   Swedish Foundation for Strategic Research;   The Swedish Research Council
Active, not recruiting - verified January 2016

Clopidogrel Response Evaluation and AnTi-Platelet InterVEntion in High Thrombotic Risk PCI Patients

Condition:   Coronary Heart Disease
Interventions:   Drug: Clopidogrel 75mg;   Drug: Clopidogrel 150mg;   Drug: Aspirin 100mg;   Drug: Cilostazol 100mg
Sponsors:   Chinese Academy of Medical Sciences, Fuwai Hospital;   Beijing Municipal Health Bureau;   Haemonetics Corporation;   Zhejiang Otsuka Pharmaceutical Co., Ltd.
Active, not recruiting - verified August 2015

Comparison of Double Kissing Culotte Stenting With Double Kissing Crush Stenting for True Bifurcation Lesions

Condition:   Coronary Heart Disease
Intervention:   Device: Resolute stents
Sponsors:   Fujian Medical University;   Jetmed(Beijing)Co.,Ltd.
Recruiting - verified February 2016

Optical Frequency Domain Imaging (OFDI) and Vascular Healing After Stent Placement Diabetics Presenting With Acute Coronary Syndrome

Condition:   Coronary Artery Disease
Intervention:   Device: Resolute Integrity stent
Sponsor:   Emory University
Active, not recruiting - verified February 2016

On-treatment PLAtelet Reactivity-guided Therapy Modification FOR ST-segment Elevation Myocardial Infarction

Condition:   Acute ST-elevation Myocardial Infarction
Intervention:   Drug: Antiplatelet Regimen Modification (aspirin or ticagrelor)
Sponsor:   Clinical Centre of Serbia
Recruiting - verified January 2016

The Effects of Ranolazine on CPET Parameters in Ischemic Cardiomyopathy Patients (ERIC)

Condition:   Cardiomyopathy
Intervention:   Drug: Ranolazine
Sponsors:   Cardiovascular Institute of the South Clinical Research Corporation;   Gilead Sciences
Recruiting - verified January 2016

Randomized Trial of Coronary Angioplasty for de Novo Lesions in sMall vesSElS With Drug Eluting Balloon.

Condition:   Coronary Disease
Interventions:   Device: Drug elluting Balloon (DEB);   Device: Drug elluting coronary stent (DES)
Sponsors:   Andres Iñiguez Romo, MD, PhD;   Hospital de Meixoeiro
Recruiting - verified January 2016

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: aleglitazar;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

A Registry to Evaluate Patterns of Care Associated With the Use of Corus® CAD in Real World Clinical Care Settings

Conditions:   Chest Pain;   Coronary Artery Disease
Intervention:  
Sponsor:   CardioDx
Completed - verified January 2016

ClearWay Rx Readmission Registry

Condition:   Acute Myocardial Infarction
Intervention:   Device: ClearWay™ Rx catheter
Sponsor:   Cardiovascular Institute of the South Clinical Research Corporation
Completed - verified January 2016

Patient Reported Outcome Measures for Ablation of Cardiac Arrhythmias

Condition:   Cardiac Arrhythmia
Interventions:   Other: Interview;   Other: Questionnaires
Sponsors:   Cardiff and Vale University Health Board;   National Institute for Health and Clinical Excellence;   University Hospital Birmingham NHS Foundation Trust;   Newcastle-upon-Tyne Hospitals NHS Trust;   University College, London
Active, not recruiting - verified February 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified February 2016

Screening for Colorectal Cancer With FOBT, Virtual Colonoscopy and Optical Colonoscopy. A Randomized Clinical Trial in the Florence District

Condition:   Colorectal Cancer
Intervention:   Other: Invitation to screening
Sponsors:   Cancer Prevention and Research Institute, Italy;   University of Florence
Recruiting - verified January 2016

A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: Placebo
Sponsor:   Genentech, Inc.
Completed - verified February 2016

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified January 2016

Coronary Artery Bypass Grafting Strategies for the Anterolateral Territory: a Prospective Randomized Clinical Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: LIMA to SVG Bridge Technique;   Procedure: Conventional CABG
Sponsors:   Centre hospitalier de l'Université de Montréal (CHUM);   Canadian Institutes of Health Research (CIHR)
Recruiting - verified January 2016

Efficacy and Safety of Ad5FGF-4 for Myocardial Ischemia in Patients With Stable Angina Due to Coronary Artery Disease

Condition:   Angina, Stable
Intervention:   Genetic: Alferminogene tadenovec
Sponsors:   Cardium Therapeutics;   Advanced Biosciences Research
Active, not recruiting - verified January 2016

A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease

Condition:   Cardiovascular Disease, Coronary Heart Disease, Dyslipidemia, Peripheral Arterial Disease (PAD)
Interventions:   Other: Background care;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   New York University School of Medicine;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University
Recruiting - verified January 2016

The Role Of Noninvasive 320-Row Multidetector Computer Tomography

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   University Health Network, Toronto;   Mount Sinai Hospital, Canada
Active, not recruiting - verified November 2015

Optimizing Expectations in Cardiac Surgery Patients

Conditions:   Coronary Artery Bypass Graft Surgery (CABG);   Patients' Expectations;   Coronary Heart Disease
Interventions:   Behavioral: Expectation Manipulation Intervention;   Behavioral: Supportive Therapy
Sponsor:   Philipps University Marburg Medical Center
Completed - verified February 2016

Comparison Between High-sensitivity Cardiac Troponin T and Standard Tnl Assays in Early Cardiac Ischemia Detection

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   University of Lausanne Hospitals
Completed - verified January 2016

Glucagon-like Peptide 1 Agonist Exenatide for Improved Glucose Control and Cardiac Function in Patients With Aortocoronary Bypass

Conditions:   Coronary Artery Disease;   Decreased Left Ventricular Function
Intervention:   Drug: Exenatide
Sponsors:   Charles University, Czech Republic;   Eli Lilly and Company
Completed - verified January 2016

Study of the Natural History of FFR Guided Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea;   St. Jude Medical (Hong Kong) Limited
Recruiting - verified January 2016

Treatment With Ranolazine in Microvascular Coronary Dysfunction (MCD): Impact on Angina Myocardial Ischemia

Condition:   Microvascular Coronary Dysfunction (MCD)
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsors:   Cedars-Sinai Medical Center;   University of Florida
Recruiting - verified January 2016

Incidence of Male Pudendal Artery Stenosis in Suboptimal Erections Study

Condition:   Erectile Dysfunction Due to Arterial Insufficiency
Intervention:  
Sponsors:   Medtronic Endovascular;   Medtronic
Terminated - verified January 2016

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

Remote Ischemic Preconditioning in High Risk Cardiovascular Surgery Patients

Conditions:   Death;   Stroke;   Low Cardiac Output Syndrome;   Myocardial Infarction;   Renal Failure;   Pulmonary Failure
Interventions:   Other: Remote ischemic preconditioning stimulus;   Other: control
Sponsor:   Queen's University
Completed - verified February 2016

A Study of RO4905417 in Patients With Non ST-Elevation Myocardial Infarction (Non-STEMI) Undergoing Percutaneous Coronary Intervention

Condition:   Myocardial Infarction
Interventions:   Procedure: Percutaneous Coronary Intervention (PCI);   Drug: RO4905417;   Drug: RO4905417;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery

Condition:   Coronary Heart Disease, Graft Occlusion, Vascular
Interventions:   Drug: Placebo;   Drug: RO4905417
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

Pain Modulation in Rheumatoid Arthritis (RA) - Influence of Adalimumab

Conditions:   Arthritis, Rheumatoid;   Pain;   Fatigue
Interventions:   Drug: adalimumab;   Drug: Placebo
Sponsors:   Karolinska Institutet;   Abbott;   Swedish Foundation for Strategic Research;   The Swedish Research Council
Recruiting - verified February 2016

Morphine In Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: morphine chlorhydrate;   Drug: saline solution
Sponsors:   French Cardiology Society;   Institut National de la Santé Et de la Recherche Médicale, France
Active, not recruiting - verified February 2016

Treatment of Coronary Artery Disease (CAD) With Bare Metal Stent (BMS) Followed by Paclitaxel-Coated Balloon Catheter Versus Paclitaxel-Eluting Stent

Condition:   Coronary Artery Disease
Interventions:   Device: Coroflex Blue (BMS) followed by SeQuent Please (DEB);   Device: Coroflex Please (DES)
Sponsor:   Aesculap AG
Active, not recruiting - verified January 2016

Antidepressants to Promote Recovery of Cardiac Patients Suffering From Depression

Conditions:   Acute Coronary Syndrome;   Major Depressive Episode
Intervention:   Drug: Citalopram
Sponsors:   Centre hospitalier de l'Université de Montréal (CHUM);   Canadian Institutes of Health Research (CIHR);   Centre de Recherche du Centre Hospitalier de l'Université de Montréal;   Montreal Heart Institute
Terminated - verified January 2016

A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease

Condition:   Cardiovascular Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Terminated - verified February 2016

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

Molecular and Morphologic Characterization of Circulating Endothelial Cells

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Scripps Translational Science Institute
Recruiting - verified January 2016

Strengthening Transplantation Effects of Bone Marrow Mononuclear Cells With Atorvastatin in Myocardial Infarction

Conditions:   Myocardial Infarction;   Stem Cell Transplantation;   Angioplasty, Transluminal, Percutaneous Coronary
Intervention:   Drug: Atorvastatin and mononuclear cells transplantation
Sponsor:   Chinese Academy of Medical Sciences, Fuwai Hospital
Enrolling by invitation - verified January 2016

Ventricular Tachycardia (VT) Ablation Versus Enhanced Drug Therapy

Condition:   Recurrent Ventricular Tachycardia
Interventions:   Procedure: Catheter Ablation;   Drug: Aggressive Antiarrhythmic Therapy (Amiodarone)
Sponsors:   John Sapp;   St. Jude Medical;   Biosense Webster, Inc.;   Canadian Institutes of Health Research (CIHR)
Completed - verified January 2016

Safety and Efficacy of SeeMore (TM) in Heart Patients

Condition:   Myocardial Infarction
Intervention:   Drug: SeeMore(TM)
Sponsor:   Eagle Vision Pharmaceutical Corp.
Completed - verified February 2016

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

Conditions:   Coronary Artery Disease;   Mitral Valve Regurgitation;   Mitral Valve Incompetence;   Heart Failure
Intervention:   Device: CEP MAGNA MITRAL PERICARDIAL BIOPROSTHESES
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified February 2016

A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients

Condition:   Coronary Heart Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Condition:   Coronary Heart Disease
Interventions:   Drug: Evidence-based medical care for Acute Coronary Syndrome;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

Ischemia Driven Enoxaparin Therapy in ACS Presenting as Low Risk (IDEAL)

Condition:   Unstable Angina
Intervention:   Drug: enoxaparin
Sponsors:   Canadian Heart Research Centre;   Sanofi
Terminated - verified January 2016

A Long Term Extension of Study NC19453 Evaluating Safety and Efficacy of RO4607381

Condition:   Coronary Heart Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

Hostility Reduction Program to Improve Autonomic Regulation of the Heart

Conditions:   Hostility;   Coronary Arteriosclerosis
Intervention:   Behavioral: CBT Hostility Reduction Program
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified December 2007

A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.

Condition:   Coronary Heart Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified February 2016

Coronary Heart Disease Incidence: Depression & Inflammation Risk

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Diseases;   Depression;   Inflammation
Intervention:  
Sponsors:   Columbia University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016

Retinal Arteriolar Abnormalities and CV Mortality

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Cerebrovascular Disorders;   Coronary Disease
Intervention:  
Sponsors:   University of Wisconsin, Madison;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2016

Minnesota Heart Survey - Mortality and Morbidity

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Diseases;   Myocardial Infarction;   Death, Sudden, Cardiac
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016

Minnesota Heart Survey - Risk Factor Survey

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Cerebrovascular Accident;   Coronary Disease;   Hypertension;   Myocardial Infarction
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016

Community Structure and Cardiovascular Mortality Trends

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Myocardial Ischemia;   Cerebrovascular Disorders;   Cerebrovascular Accident
Intervention:  
Sponsors:   University of North Carolina, Chapel Hill;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2016

Novel Hemostatic Cardiac Risk Factors in Framingham

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Death, Sudden, Cardiac;   Myocardial Infarction;   Thrombosis;   Atherosclerosis;   Carotid Artery Diseases
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified March 2005

Intermittent ST Depression and Prognosis After Myocardial Infarction

Conditions:   Cardiovascular Diseases;   Myocardial Infarction;   Heart Diseases
Intervention:  
Sponsors:   New York University School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2016