Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Acute Vascular Response to Exercise in Women With Nonobstructive Coronary Artery Disease

Condition:   Nonobstructive Coronary Artery Disease
Intervention:   Other: Slow-paced walking
Sponsor:   University of Florida
Not yet recruiting - verified May 2015

Cardiovascular Epidemiology in Russian Federation

Conditions:   Hypertension;   Coronary Artery Disease;   Diabetes;   Heart Failure;   Smoking;   Lifestyle
Intervention:  
Sponsors:   Federal North-West Medical Research Centre;   National Research Center for Preventive Medicine;   Russian Cardiology Research and Production Center
Recruiting - verified May 2015

A Prospective, Single-Blinded, Multi-Center, Randomized, Controlled, Registered Clinical Trial on the Efficacy and Safety of Sirolimus-Eluting Stent (MiStent® System) in the Treatment of Patients With Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Device: MiStentTM;   Device: TIVOLI
Sponsors:   Micell Technologies;   Hefei Life Science Medical Instruments Co. Ltd.;   Giant Med-Pharma Services Inc.;   CCRF Consulting Co., Ltd.
Not yet recruiting - verified May 2015

Effects of Ivabradine in Patients With Stable Coronary Artery Disease Without Clinical Heart Failure

Condition:   Coronary Artery Disease.
Interventions:   Drug: Ivabradine;   Drug: Placebo
Sponsor:   Servier
Completed - verified May 2015

Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery

Condition:   Coronary Artery Disease
Interventions:   Drug: Sitagliptin;   Drug: Placebo;   Drug: Regular Human Insulin;   Drug: Insulin glargine;   Drug: Supplemental insulin (Insulin lispro);   Drug: Supplemental insulin (Insulin aspart)
Sponsor:   Emory University
Not yet recruiting - verified May 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified May 2015

Ultrasound-guided Intermediate Cervical Plexus Block for Carotid Surgery

Condition:   Carotid Artery Stenosis
Intervention:   Procedure: Ultrasound-guided intermediate cervical plexus block
Sponsor:   Institut Mutualiste Montsouris
Completed - verified May 2015

Plasma and Platelet microRNAs in Clopidogrel Low Response Patients

Condition:   Coronary Artery Disease
Interventions:   Drug: Clopidogrel;   Drug: acetylsalicylic acid (ASA)
Sponsors:   The First Hospital of Nanjing Medical University;   National Natural Science Foundation of China
Not yet recruiting - verified May 2015

Late Reperfusion With Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction

Conditions:   Ischemic Heart Disease;   ST-segment Elevation Myocardial Infarction
Intervention:   Procedure: PCI
Sponsor:   Thomas Engstrom
Recruiting - verified May 2015

A Phase I Study to Assess Ebola Vaccines cAd3-EBO Z and MVA-EBO Z

Condition:   Ebola Virus Disease
Interventions:   Biological: MVA-EBO Z;   Biological: ChAd3-EBO Z
Sponsor:   University of Oxford
Recruiting - verified May 2015

Prospective Registry of Acute Heart Failure

Condition:   Acute Heart Failure
Intervention:   Procedure: blood sample
Sponsor:   Sebastian Carballo
Recruiting - verified May 2015

Heart Failure STratification and OutcomeS

Condition:   HEART FAILURE
Intervention:   Other: Stratification and outcomes
Sponsor:   Jordi Gol i Gurina Foundation
Recruiting - verified January 2015

High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis (Tyrolean Aortic Stenosis Study-2)

Conditions:   Aortic Stenosis;   Heart Failure;   Syncope;   Angina Pectoris
Intervention:   Procedure: Aortic Valve Intervention (surgical or transcatheter)
Sponsor:   Medical University Innsbruck
Not yet recruiting - verified May 2015

Ugandan Non-Communicable Diseases and Aging Cohort

Conditions:   HIV;   Cardiovascular Disease;   Chronic Obstructive Pulmonary Disease;   Atherosclerosis;   Hypertension;   Diabetes Mellitus
Intervention:   Other: This is an observational study only
Sponsors:   Massachusetts General Hospital;   Mbarara University of Science and Technology;   University of California, San Francisco;   Ragon Institute of MGH, MIT and Harvard;   National Institutes of Health (NIH);   Harvard Center for AIDS Research
Recruiting - verified May 2015

Effects of Nicorandil on Cardiac Infarct Size in Patients With ST-segment Elevation Acute Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Drug: Nicorandil
Sponsors:   Pusan National University Hospital;   JW Pharmaceutical
Recruiting - verified May 2015

The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome

Conditions:   Depression;   Acute Coronary Syndrome
Interventions:   Drug: Melatonin (N-acetyl-5-methoxytryptamine);   Drug: Placebo
Sponsors:   Roskilde County Hospital;   Psychiatric Research Unit, Region Zealand, Denmark;   University of Copenhagen;   Pharma Nord
Not yet recruiting - verified May 2015

Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome

Conditions:   Cardiac Death;   Hemorrhage;   Cerebrovascular Accident;   Myocardial Infarction
Interventions:   Device: BES (biodegradable polymer biolimus-eluting stent);   Drug: Prasugel;   Drug: Clopidogrel
Sponsor:   Chonnam National University Hospital
Recruiting - verified May 2015

VRC 208: Dose, Safety and Immunogenicity of a Recombinant Modified Vaccinia Virus Ankara Ebola Vaccine, VRC-EBOMVA079-00-VP (MVA-EbolaZ), Administered Alone or as a Boost to cAd3-Ebola Vaccines in Healthy Adults

Condition:   Healthy Adult Immune Responses to Vaccine
Interventions:   Biological: VRC-EBOMVA079-00-VP (MVA-EbolaZ);   Biological: VRC-EBOADC069-00-VP (cAd3-EBO)
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified March 2015

COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Exenatide;   Other: Remote Ischemic Conditioning (RIC)
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Not yet recruiting - verified March 2015

Brilinta Taiwan Post Approval Safety Study

Condition:   Non ST-elevation Myocardial Infarction
Intervention:   Drug: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Ebola CVD-Mali #2000 (Bivalent) VRC-EBOAdc069-00-vp (cAd3-EBO)

Conditions:   Ebola Virus Disease;   Hemorrhagic Fever
Interventions:   Biological: VRC-EBOADC069-00-vp;   Biological: VRC-EBOADC069-00-vp
Sponsors:   University of Maryland;   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified February 2015

Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Procedure: Computed tomography angiography (cardiac CT);   Procedure: Invasive coronary angiography (ICA)
Sponsor:   Charite University, Berlin, Germany
Not yet recruiting - verified May 2015

P3AMI Antiplatelet Trial

Condition:   Heart Attack
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel;   Drug: ticagrelor
Sponsor:   The Royal Wolverhampton Hospitals NHS Trust
Recruiting - verified May 2015

The Use of Texting Messaging to Improve the Hospital-to-community Transition Period in Cardiovascular Disease Patients

Conditions:   Cardiovascular Disease;   Acute Coronary Syndrome
Intervention:   Behavioral: Txt2Prevent
Sponsors:   Simon Fraser University;   Providence Health & Services;   University of British Columbia;   McMaster University;   Canadian Institutes of Health Research  (CIHR)
Not yet recruiting - verified May 2015

Human Umbilical Cord Stroma MSC in Myocardial Infarction

Conditions:   Chronic Ischemic Cardiomyopathy;   Coronary Artery Bypass Surgery
Intervention:   Biological: stem cell transplantation
Sponsors:   Ankara University;   Hacettepe University;   Turkiye Yuksek Ihtisas Education and Research Hospital;   ATIGEN-CELL;   Dr. Sami Ulus Children's Hospital;   Yildirim Beyazit University
Recruiting - verified May 2015

Liraglutide to Improve corONary Haemodynamics During Exercise streSS

Conditions:   Ischaemic Heart Disease;   Coronary Heart Disease;   Chronic Stable Angina
Interventions:   Drug: Liraglutide;   Other: Placebo
Sponsors:   King's College London;   Guy's and St Thomas' NHS Foundation Trust
Completed - verified May 2015

Is Glucagon-like Peptide-1 Insufficiency a Residual Risk in Coronary Artery Disease?

Condition:   Coronary Artery Disease
Intervention:   Other: Determination of plasma GLP-1 level
Sponsors:   Sapporo Medical University;   Merck Sharp & Dohme Corp.
Recruiting - verified May 2015

The Effects of Rhus Coriaria L. (Sumac) on Serum Lipid Levels of Patients With Hyperlipidemia

Condition:   Hyperlipidemias
Interventions:   Drug: Rhus Coriaria L. (Sumac);   Drug: Placebo
Sponsor:   Shiraz University of Medical Sciences
Completed - verified May 2015

A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction

Conditions:   Heart Attack;   NSTEMI
Interventions:   Biological: AMI MultiStem cells;   Other: Sham
Sponsors:   Athersys, Inc;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified May 2015

Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Condition:   Hypercholesterolemia
Intervention:   Biological: Evolocumab
Sponsor:   Amgen
Enrolling by invitation - verified May 2015

Real Life Long-term Adherence to Ticagrelor After PCI for Acute Coronary Syndromes

Condition:   Acute Coronary Syndrome (ACS)
Intervention:   Drug: Ticagrelor
Sponsor:   IHF GmbH - Institut für Herzinfarktforschung
Active, not recruiting - verified May 2015

Study Of Costs Realized After Percutaneous Coronary intervenTion Employing Same Day Discharge

Condition:   Coronary Artery Disease
Intervention:   Procedure: Same day discharge
Sponsors:   Saint Joseph Mercy Health System;   Michigan Heart;   Blue Cross Blue Shield of Michigan Foundation
Suspended - verified May 2015

Russian Familial Hypercholesterolemia Registry

Condition:   Familial Hypercholesterolemia
Intervention:  
Sponsors:   Russian Cardiology Research and Production Center;   Russian National Atherosclerosis Society;   Samara State Medical University;   Novosibirsk Research Institute of Internal Medicine;   St. Petersburg State Pavlov Medical University;   Chelyabinsk State Medical Academy;   International Atherosclerosis Society;   INVITRO Research Laboratory;   Pfizer;   Amgen;   AstraZeneca;   Pharmstandard
Recruiting - verified May 2015

The PAtient Preference Analysis of Yearly Follow-up After PCI (PAPAYA)

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Thorax Centrum Twente
Completed - verified May 2015

CONTRAST (Can cONTrast Injection Better Approximate FFR compAred to Pure reSTing Physiology?)

Condition:   Coronary Artery Disease
Interventions:   Drug: Adenosine;   Drug: Contrast Media;   Drug: Resting conditions
Sponsors:   The University of Texas Health Science Center, Houston;   St. Jude Medical
Completed - verified May 2015

TandemHeart to Reduce Infarct Size (TRIS Trial)

Condition:   Acute Myocardial Infarction
Interventions:   Device: TandemHeart System;   Procedure: Percutaneous coronary intervention
Sponsor:   CardiacAssist, Inc.
Recruiting - verified May 2015

Correlational Study on the Biomarkers Application to the Prediction and Diagnosis of Cardiovascular Diseases

Condition:   Coronary Artery Disease.
Intervention:   Procedure: coronary angiography
Sponsor:   Taipei City Hospital
Recruiting - verified June 2014

Is the 4MGS a Useful Outcome Measure Post-PPCI

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsors:   Royal Brompton & Harefield NHS Foundation Trust;   Medical Research Council
Recruiting - verified May 2015

Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects

Conditions:   Type 2 Diabetes;   Coronary Artery Disease
Intervention:  
Sponsors:   British Cardiac Research Trust;   Royal Free Hospital NHS Foundation Trust;   London North West Healthcare NHS Trust;   Barnet and Chase Farm Hospitals NHS Trust;   Diabetes and Obesity Research Network;   Lund University;   Health Diagnostic Laboratory, Inc.
Recruiting - verified May 2015

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL112;   Biological: Placebo
Sponsor:   CSL Behring
Recruiting - verified May 2015

Impact of Continuous Positive Airway Pressure (CPAP) Therapy on Outcomes in Patients Undergoing Coronary Revascularization

Conditions:   Obstructive Sleep Apnea;   Ischaemic Heart Desease
Intervention:   Device: CPAP
Sponsor:   Beijing Anzhen Hospital
Recruiting - verified March 2014

Autologous Bone Marrow Mononuclear Cells in the Combined Treatment of Coronary Heart Disease

Condition:   Ischemic Heart Disease
Intervention:   Procedure: coronary artery bypass grafting with administration of autologous bone marrow stem cells
Sponsor:   St. Petersburg State Pavlov Medical University
Recruiting - verified September 2014

The CardioPAT Project: A Randomized Trial

Conditions:   Coronary Artery Disease;   Aortic Stenosis;   Aortic Insufficiency;   Mitral Insufficiency;   Aortic Aneurysm
Intervention:   Device: cardioPAT cell saver
Sponsor:   Rigshospitalet, Denmark
Terminated - verified May 2015

Prasugrel and Ticagrelor in ST-segment Elevation Myocardial Infarction

Condition:   ST-Segment Elevation Myocardial Infarction
Interventions:   Drug: Prasugrel 60 mg;   Drug: Ticagrelor 180 mg
Sponsor:   Dong-A University
Terminated - verified May 2015

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Conditions:   Drug Use;   Alcohol Use;   Congestive Heart Failure;   Pneumonia;   Acute Myocardial Infarction;   Diabetes Mellitus;   Chronic Obstructive Pulmonary Disease;   End-Stage Renal Disease
Interventions:   Behavioral: Specialized Community Disease Management;   Behavioral: Treatment As Usual
Sponsors:   Treatment Research Institute;   Patient Centered Outcome Research Institute
Recruiting - verified May 2015

Swedish Drug-elution Trial in Peripheral Arterial Disease

Conditions:   Peripheral Arterial Disease;   Critical Limb Ischemia;   Intermittent Claudication
Interventions:   Procedure: Revascularization with drug-eluting technology;   Procedure: Revascularization without drug-eluting technology;   Device: drug-coated balloons and/or drug-eluting stents
Sponsors:   Sahlgrenska University Hospital, Sweden;   The Swedish Research Council;   Swedish Heart Lung Foundation;   Uppsala University;   The Swedish National Registry for Vascular Surgery
Recruiting - verified May 2015

Hypoglycemia (Low Blood Sugar) and the Heart

Conditions:   Hypoglycemia;   Type 2 Diabetes
Intervention:  
Sponsor:   University of British Columbia
Recruiting - verified May 2015

To Study the Safety and Clinical Outcomes of the Absorb Bioresorbable Vascular Scaffold (BVS) System in Patients With de Novo Lesions in Previously Untreated Vessels

Conditions:   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Intervention:   Device: Absorb BVS
Sponsor:   Abbott Vascular
Recruiting - verified May 2015

First in Man Study of the DREAMS 2nd Generation Drug Eluting Absorbable Metal Scaffold (BIOSOLVE-II)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis
Intervention:   Device: Percutaneous Coronary Intervention (DREAMS) stenting
Sponsor:   Biotronik AG
Recruiting - verified May 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified May 2015

A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ ABSORB CHINA Randomized Controlled Trial (RCT)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: XIENCE V EECSS;   Device: ABSORB BVS System
Sponsor:   Abbott Vascular
Active, not recruiting - verified May 2015

Study of GSK1278863 to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm Repair

Condition:   Surgical Procedures
Interventions:   Drug: GSK1278863;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Active, not recruiting - verified April 2015

Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD) Including GSPECT (Gated Single Photon Emission Computed Tomography)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Recruiting - verified May 2015

Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Active, not recruiting - verified May 2015

Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention

Condition:   Acute ST Segment Elevation Myocardial Infarction
Interventions:   Drug: NAC;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified October 2014

Optical Frequency Domain Imaging (OFDI) Assessed Strut Coverage of New Terumo DES

Condition:   Coronary Artery Disease
Intervention:   Device: TCD-10023 drug eluting stent
Sponsor:   Terumo Europe N.V.
Active, not recruiting - verified May 2015

Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Interventions:   Drug: N-acetyl cysteine;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified October 2014

Ticagrelor vs Clopidogrel Effect on MFR in CAD Population

Condition:   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting - verified May 2015

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified May 2015

Angina Prevalence and Provider Evaluation of Angina Relief

Condition:   Stable Coronary Artery Disease (CAD).
Intervention:  
Sponsors:   Saint Luke's Health System;   Gilead Sciences
Enrolling by invitation - verified May 2015

Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)

Condition:   Ischemic Heart Disease
Intervention:   Other: Inhaled anaesthetic agent
Sponsor:   Region Skane
Completed - verified May 2015

Phase III Trial of Dantonic® (T89) Capsule to Prevent and Treat Stable Angina

Condition:   Angina Pectoris
Interventions:   Drug: T89 high dose;   Drug: T89 Low dose;   Drug: Sanqi+Bingpian;   Drug: Placebo
Sponsor:   Tasly Pharmaceuticals, Inc.
Recruiting - verified May 2015

China PEACE-Prospective PCI Study

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   China National Center for Cardiovascular Diseases;   Ministry of Health, China
Active, not recruiting - verified May 2015

China PEACE-Prospective AMI Study

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   China National Center for Cardiovascular Diseases;   Ministry of Health, China
Active, not recruiting - verified May 2015

Efficacy of Physical Exercise in Cardiac Rehabilitation

Conditions:   Coronary Heart Disease;   Heart Failure;   Ischemic Heart Diseases
Interventions:   Other: Supervised physical exercise training x3 weekly for 12 weeks;   Other: Supervised physical exercise training x2 weekly for 8 weeks
Sponsors:   Aarhus University Hospital Skejby;   Institute for Clinical and Experimental Medicine
Completed - verified May 2015

The Effects of Cardiac Rehabilitation on Cardiovascular Disease Risk in Rheumatoid Arthritis Patients

Condition:   Rheumatoid Arthritis
Intervention:   Behavioral: Exercise
Sponsor:   Nova Scotia Health Authority
Suspended - verified February 2015

Evaluating Cardiovascular Phenotypes Using Induced Pluripotent Stem Cells

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Scripps Translational Science Institute
Enrolling by invitation - verified May 2015

Antazoline in Rapid Cardioversion of Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: antazoline;   Drug: 0.9% saline
Sponsor:   Institute of Cardiology, Warsaw, Poland
Completed - verified May 2015

Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Injection of Cyclosporin;   Drug: Placebo;   Procedure: Echocardiography
Sponsor:   Hospices Civils de Lyon
Active, not recruiting - verified April 2015

The Effect on Fluid Balance After Cardiac Surgery After Use of Two Different Priming Protocols

Condition:   Coronary Heart Disease
Interventions:   Drug: Tetraspan;   Drug: acetated Ringer`s solution
Sponsor:   Haukeland University Hospital
Completed - verified August 2013

Efficacy of LCQ908 on Cardiovascular Risk

Conditions:   Coronary Artery Disease;   Hypertriglyceridemia
Interventions:   Drug: LCQ908;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Terminated - verified May 2015

Plasmonic Photothermal and Stem Cell Therapy of Atherosclerosis Versus Stenting

Conditions:   Coronary Artery Disease;   Atherosclerosis
Interventions:   Other: Stenting and micro-infusion of NP;   Device: Implantation of everolimus-eluting stent
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation;   Ural Federal University
Terminated - verified May 2015

Accuracy of Half of the Usual Radiotracer Dose in SPECT

Condition:   Coronary Artery Disease
Intervention:   Radiation: 1/2 dose of 99mTc OR 201Tl tracers
Sponsor:   Ottawa Heart Institute Research Corporation
Completed - verified May 2015

Prospective, Randomised Study: Metabolic and Functional Effects of Bariatric Surgery Accessed Using Positron Emission Tomography (PET) and MRI.

Condition:   Morbid Obesity
Intervention:   Procedure: Bariatric surgery
Sponsor:   Turku University Hospital
Recruiting - verified May 2015

Intramyocardial Multiple Precision Injection of Bone Marrow Mononuclear Cells in Myocardial Ischemia

Condition:   Heart Failure
Interventions:   Procedure: NOGA XP Cardiac Navigation System;   Procedure: NOGA XP Cardiac Navigation System
Sponsor:   Federal North-West Medical Research Centre
Recruiting - verified January 2014

Trial of an Internet-based Platform for Managing Chronic Diseases at a Distance

Conditions:   Ischemic Heart Disease;   Heart Failure;   Chronic Kidney Disease;   Diabetes;   Chronic Obstructive Pulmonary Disease
Intervention:   Behavioral: iCDM
Sponsors:   Simon Fraser University;   Canadian Institutes of Health Research  (CIHR);   Michael Smith Foundation for Health Research
Active, not recruiting - verified May 2015

Ranibizumab and the Risk of Arterial Thromboembolic Events

Conditions:   Age-related Macular Degeneration;   Coronary Artery Disease;   Cerebrovascular Disorders
Interventions:   Drug: 0.5 mg of ranibizumab;   Procedure: 0.5 mg of ranibizumab + photodynamic therapy;   Other: Sham injection
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation
Terminated - verified May 2015

Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)

Condition:   Atherosclerosis
Interventions:   Drug: Canakinumab;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting - verified May 2015

Investigate Effect on Mean IMT of Probucol And/or CilosTazol in Patients With Coronary Heart dIsease Taking HMGCoA Reductase Inhibitor Therapy

Condition:   Hyperlipidemias
Interventions:   Drug: HMGCoA reductase inhibitor;   Drug: HMGCoA reductase inhibitor + probucol;   Drug: HMGCA reductase inhibitor + probucol + cilostazol
Sponsors:   Seoul National University Hospital;   Korea Otsuka Pharmaceutical Co.,Ltd.
Active, not recruiting - verified May 2015

e-NOBORI Observational Registry of Nobori DES

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Terumo Europe N.V.
Active, not recruiting - verified May 2015

Prospective, Single Blind, Randomized Controlled Study to Evaluate the Safety & Effectiveness of the Tryton Side Branch Stent Used With DES in Treatment of de Novo Bifurcation Lesions in the Main Branch & Side Branch in Native Coronaries

Condition:   Coronary Artery Disease, de Novo Bifurcation Lesions of the Main and Side Branch Within Native Coronaries
Interventions:   Device: Tryton Side Branch Stent with main branch DES;   Device: POBA
Sponsor:   Tryton Medical, Inc.
Recruiting - verified May 2015

A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery

Condition:   Coronary Heart Disease, Graft Occlusion, Vascular
Interventions:   Drug: Placebo;   Drug: RO4905417
Sponsor:   Hoffmann-La Roche
Completed - verified May 2015

Invasive Revascularization or Not in Intermittent Claudication

Condition:   Intermittent Claudication
Interventions:   Procedure: INVASIVE (INV) treatment;   Other: Best medical treatment (BMT)
Sponsors:   Sahlgrenska University Hospital, Sweden;   Göteborg University
Active, not recruiting - verified May 2015

Mediators of Atherosclerosis in South Asians Living in America

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Coronary Artery Disease;   Coronary Disease
Intervention:  
Sponsors:   University of California, San Francisco;   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified May 2015

Registry of Acute Coronary Syndromes in the Lazio Region of Italy

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsors:   San Filippo Neri General Hospital;   Associazione Nazionale Medici Cardiologi Ospedalieri
Recruiting - verified May 2015

PROspective Multicenter Imaging Study for Evaluation of Chest Pain

Condition:   Chest Pain
Interventions:   Device: Coronary Angiography;   Device: Stress Echocardiogram;   Device: Nuclear Stress Test;   Device: Exercise Electrocardiogram
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified March 2015

Detecting Heart Disease Using First Pass Imaging With Gated SPECT Perfusion

Condition:   Ischemic Heart Disease
Intervention:  
Sponsors:   Yale University;   Astellas Pharma US, Inc.
Completed - verified May 2015

FAME II - Fractional Flow Reserve (FFR) Guided Percutaneous Coronary Intervention (PCI) Plus Optimal Medical Treatment (OMT) Verses OMT

Condition:   Coronary Artery Disease
Interventions:   Other: Stenting plus OMT;   Other: Standard of care
Sponsor:   St. Jude Medical
Active, not recruiting - verified May 2015

Improving the Results of Heart Bypass Surgery Using New Approaches to Surgery and Medication

Condition:   Coronary Artery Disease
Interventions:   Procedure: No-touch SVG harvest vs conventional SVG harvest technique;   Dietary Supplement: Fish oil supplementation vs placebo
Sponsors:   Sunnybrook Health Sciences Centre;   Hamilton Health Sciences Corporation
Active, not recruiting - verified November 2011

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified May 2015

EndocardialVascularEndothelialGrowth Factor D(VEGF-D)Gene Therapy for the Treatment of Severe Coronary Heart Disease

Conditions:   Angina Pectoris;   Myocardial Infarction
Intervention:   Biological: VEGF-D gene transfer
Sponsors:   Kuopio University Hospital;   University of Eastern Finland
Active, not recruiting - verified May 2015

The Healthy Elderly Longevity Cohort

Condition:   Healthy
Intervention:  
Sponsor:   Scripps Translational Science Institute
Recruiting - verified May 2015

Molecular and Morphologic Characterization of Circulating Endothelial Cells

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Scripps Translational Science Institute
Recruiting - verified May 2015

Fibrinogen and Bleeding After Cardiac Surgery

Conditions:   Complications;   Bleeding;   Coronary Artery Disease
Intervention:   Drug: Fibrinogen
Sponsor:   Sahlgrenska University Hospital, Sweden
Completed - verified May 2015

Comparison of Individual Computer Aided Design/Manufactured (CAD/CAM) - Based Implants Consisting on Hydroxylapatite and Titanium to be Used in Cranioplasty

Conditions:   Skull Defects;   Cranioplasty
Interventions:   Device: Titanium implant (CranioConstruct™);   Device: Hydroxylapatite (CustomBone)
Sponsors:   University of Leipzig;   Klinik für Neurochirurgie Universitatsklinikum Leipzig AöR
Terminated - verified May 2015

Cardiovascular Magnetic Resonance for the Occluded Infarct-Related Artery Treatment

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Myocardial Infarction;   Heart Failure
Interventions:   Drug: Beta adrenergic blockers;   Drug: Platelet inhibitors;   Drug: Statins;   Drug: ACE inhibitors and/or ARB and/or AA;   Procedure: PCI with stenting
Sponsor:   Institute of Cardiology, Warsaw, Poland
Terminated - verified May 2015

Epigenetic Markers of B-Cell Function in Low Birth Weight Infants

Conditions:   Low Birth Weight;   Small for Gestational Age;   Immunodeficiency
Intervention:   Other: Cord blood collection for analysis
Sponsors:   University of Utah;   Department of Health and Human Services
Completed - verified June 2012

Prochymal® (Human Adult Stem Cells) Intravenous Infusion Following Acute Myocardial Infarction (AMI)

Condition:   Myocardial Infarction
Interventions:   Drug: Prochymal®;   Drug: Placebo
Sponsor:   Mesoblast International Sàrl
Active, not recruiting - verified May 2015

A Clinical Evaluation of Everolimus Eluting Coronary Stents in the Treatment of Patients With ST-segment Elevation Myocardial Infarction: EXAMINATION Study

Condition:   Myocardial Infarction
Interventions:   Drug: Everolimus Eluting Coronary Stent System;   Device: cobalt chromium balloon expandable stent ( non drug eluting stent Arm)
Sponsor:   Spanish Society of Cardiology
Completed - verified May 2015

Trial of a Cardiac Rehabilitation Program Delivered Remotely Through the Internet

Condition:   Cardiovascular Disease
Intervention:   Behavioral: vCRP
Sponsors:   Simon Fraser University;   Heart and Stroke Foundation of Canada
Completed - verified May 2015

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Condition:   Coronary Heart Disease
Interventions:   Drug: Evidence-based medical care for Acute Coronary Syndrome;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified May 2015

Improving Medication Adherence in Post-ACS Patients

Conditions:   Medication Adherence;   Acute Coronary Syndrome
Intervention:   Behavioral: PST therapy
Sponsors:   Columbia University;   National Heart, Lung, and Blood Institute (NHLBI)
Terminated - verified May 2015

Insulin Resistance and Atherosclerosis in Women With Lupus

Conditions:   Systemic Lupus Erythematosus;   Insulin Resistance;   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed - verified May 2015

XIENCE V: SPIRIT WOMEN

Conditions:   Coronary Artery Stenosis;   Coronary Arteriosclerosis;   Coronary Artery Disease;   Coronary Artery Restenosis;   Total Coronary Occlusion;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia
Intervention:   Device: XIENCE V®/ XIENCE PRIME™
Sponsor:   Abbott Vascular
Completed - verified May 2015

Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study)

Conditions:   Heart Failure;   Coronary Disease;   Heart Valve Diseases;   Cardiomyopathies;   Left Ventricular Hypertrophy
Intervention:  
Sponsor:   Hiroaki Shimokawa, MD, PhD
Active, not recruiting - verified May 2015

Frontier Registry II Bifurcation Stent System Registry

Condition:   Coronary Artery Disease
Intervention:   Device: Multi-Link Frontier Coronary Stent System
Sponsor:   Abbott Vascular
Withdrawn - verified May 2015

The Impact of Post Discharge One-Time Home Visit: Bridging the Gap Between Hospital and Home.

Conditions:   COPD;   Coronary Artery Disease;   Diabetes Mellitus;   Stroke
Intervention:  
Sponsor:   Maimonides Medical Center
Withdrawn - verified May 2015

Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack.

Conditions:   Ischemic Heart Failure;   Ischemic Heart Disease;   Ischemic Cardiomyopathy
Intervention:   Drug: Cellular Therapy (Cultured Autologous Skeletal Myoblast Transplantation)
Sponsor:   Genzyme, a Sanofi Company
Terminated - verified May 2015

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