Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

PGE1 Improves Coronary Microcirculation Dysfunction in Patients With CAD and Diabetes

Condition:   Coronary Microvascular Perfusion in Patients With Ischemic Heart Disease
Intervention:   Drug: Lipo-PGE1
Sponsor:   Tongji Hospital
Active, not recruiting - verified May 2017

Predictive Value Of Admission Blood Glucose Level In Patients With Acute Myocardial Infarction

Condition:   Predictive Value of Admission Blood Glucose Level in Acute Myocardial Infarction
Intervention:   Diagnostic Test: Blood Glucose Level
Sponsor:   Assiut University
Not yet recruiting - verified May 2017

Development of a Risk Prediction Algorithm Through the Investigation of Genetic Risk Factors and the Complexity of Coronary Artery Disease to Estimate Future Risk of Cardiovascular Events: Angiographic (SYNTAX Score), Clinical and Pharmacogenetic Analysis.

Condition:   Coronary Artery Disease
Intervention:   Genetic: SNPs associated with CAD, SNPs associated with pharmacological response to clopidogrel and statins
Sponsors:   AHEPA University Hospital;   LABNET IAE - Private Reference Diagnostic Laboratory
Not yet recruiting - verified May 2017

The Prospective Cohort Study on the Benefit-risk of Antithrombotic or Anticoagulant Therapy in Patients With Unruptured Intracranial Aneurysms Associated With Ischemic Heart Disease or Ischemic Cerebrovascular Disease

Conditions:   Intracranial Aneurysm;   Natural History;   Ischemic Heart Disease;   Ischemic Cerebrovascular Disease
Intervention:  
Sponsors:   Liu Zhiyong;   Xuanwu Hospital, Beijing
Not yet recruiting - verified May 2017

Watermelon Focused Dietary Inflammatory Index Intervention

Conditions:   Inflammation;   Diet Modification
Interventions:   Behavioral: DII-Based Counseling System;   Behavioral: general health education control
Sponsors:   Connecting Health Innovation;   National Watermelon Promotion Board
Not yet recruiting - verified May 2017

Thyroid Dysfunction in Patients With Type 2 Diabetes With Early Diabetic Nephropathy.

Condition:   Evaluation Thyroid Functions in Diabetic Patient
Intervention:  
Sponsor:   Assiut University
Enrolling by invitation - verified May 2017

Stress CMR in Patients With Coronary Chronic Total Occlusions

Condition:   Coronary Chronic Total Occlusions
Intervention:   Procedure: PCI
Sponsor:   Ospedale San Donato
Not yet recruiting - verified May 2017

Safety and Efficacy of Three Local Block Techniques for Diabetic Foot Surgery

Condition:   Anesthesia, Regional
Interventions:   Procedure: sciatic nerve block;   Procedure: ankle block;   Drug: Bupivacaine
Sponsor:   Assiut University
Not yet recruiting - verified May 2017

Presentations of Hypertrophic Cardiomyopathy on Myocardial Perfusion Imaging

Conditions:   Hypertrophic Cardiomyopathy;   Myocardial Perfusion Imaging
Intervention:   Diagnostic Test: myocardial perfusion imaging
Sponsor:   Far Eastern Memorial Hospital
Recruiting - verified May 2017

Aortic-Radial Pressure Gradients Post CPB

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   University of Iowa
Recruiting - verified May 2017

Catheter Ablation for Nonsustained Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy

Conditions:   Ventricular Tachycardia;   Ischemic Cardiomyopathy;   Reduced LVEF
Interventions:   Procedure: VT ablation;   Other: medication
Sponsor:   Heinrich-Heine University, Duesseldorf
Recruiting - verified May 2017

Comparative Study Between Intravascular Ultrasonography Guided and Angiography-guided Recanalization of Coronary Chronic Total Occlusions

Condition:   Coronary Occlusion
Intervention:   Device: intravascular ultrasonography
Sponsor:   Assiut University
Not yet recruiting - verified May 2017

Right Ventricular Involvement in Inferior Myocardial Infarction Patients Using 2 Dimensional Speckle Tracking Echocardiography

Condition:   Acute Myocardial Infarction of Inferior Wall Involving Right Ventricle (Disorder)
Intervention:   Diagnostic Test: Two dimensional Echocardiography
Sponsor:   Assiut University
Not yet recruiting - verified May 2017

CES1 Crossover Trial of Clopidogrel and Ticagrelor

Conditions:   Myocardial Infarction;   Thrombosis;   Platelet Dysfunction
Interventions:   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsor:   University of Maryland
Not yet recruiting - verified May 2017

Acute Myocardial Infarction and Acute Cerebral Infarction (AMIAC) Registry and Follow-up

Conditions:   Myocardial Infarction;   Cerebral Infarction;   Chronic Kidney Diseases;   Mortality
Intervention:  
Sponsor:   Guangdong General Hospital
Active, not recruiting - verified May 2017

COlchicine for Left VEntricular Remodeling Treatment in Acute Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Drug: Colchicine group (experimental arm);   Drug: Placebo group (control arm)
Sponsor:   Hospices Civils de Lyon
Not yet recruiting - verified May 2017

Transcriptome Study of Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Beijing Institute of Heart, Lung and Blood Vessel Diseases
Not yet recruiting - verified May 2017

The Incidence, Effect and Persistence of Fragmented-QRS, in Patients Presenting With ST-Elevation Myocardial Infarction

Condition:   ST Elevation Myocardial Infarction
Intervention:  
Sponsor:   The Royal Wolverhampton Hospitals NHS Trust
Not yet recruiting - verified May 2017

PCB for Long De Novo Lesions of Main Coronary Arteries (D-Lesion Long Trial)

Conditions:   Stable Angina Pectoris;   Unstable Angina Pectoris
Intervention:   Device: Paclitaxel-Coated Balloon
Sponsor:   The People's Hospital of Liaoning Province
Not yet recruiting - verified May 2017

The Evaluation of Endothelial Function in the Diagnosis of Acute Coronary Syndrome (ACS)

Conditions:   Chest Pain;   Acute Coronary Syndrome
Intervention:   Device: Digital plethysmography in the diagnosis of Acute Coronary Syndrome
Sponsor:   University of Monastir
Recruiting - verified May 2017

Optimizing the Anticoagulation Regimen of Enoxaparin During Percutaneous Coronary Intervention (OPTIENOX-PCI)

Conditions:   Coronary Artery Disease;   Percutaneous Coronary Intervention
Interventions:   Drug: Enoxaparin (Staged-dose PCI Group);   Drug: Enoxaparin (Single-dose PCI Group);   Drug: Enoxaparin (High-dose Group);   Drug: Enoxaparin (Standard-dose Group)
Sponsor:   Peking Union Medical College Hospital
Recruiting - verified May 2017

Combined Application of Remote and Intra-Coronary Ischemic Conditioning in Acute Myocardial Infarction

Condition:   Myocardial Infarction, Acute
Interventions:   Device: Remote ischemic conditioning and intracoronary ischemic conditioning;   Device: Patients with no remote ischemic conditioning and no intracoronary ischemic conditioning
Sponsor:   Hospices Civils de Lyon
Not yet recruiting - verified May 2017

Side Branch FFR After Provisional Stenting

Condition:   Coronary Artery Disease
Interventions:   Device: Rotational atherectomy;   Device: Cutting Balloon Angioplasty
Sponsor:   Icahn School of Medicine at Mount Sinai
Recruiting - verified May 2017

Coronary Anatomy Study and Times Since the Onset of Acute Myocardial Infarction Symptoms in Women Until the Opening of the Artery (TAPAC Study)

Condition:   Myocardial Infarction
Intervention:   Other: Non intervention
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Not yet recruiting - verified April 2017

Optical Coherence Tomography in Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   STEMI - ST Elevation Myocardial Infarction;   NSTEMI - Non-ST Segment Elevation MI;   Atherosclerosis, Coronary
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Berlin Institut of Health (BIH), Germany
Recruiting - verified May 2017

ICBMC-AMI. IntraCoronary Bone Marrow Mononuclear Cells in Acute Myocardial Infarction (AMI)

Conditions:   Acute Myocardial Infarction;   Heart Failure
Interventions:   Biological: Intracoronary injection of stem cell;   Biological: Placebo
Sponsor:   SCARM Institute, Tabriz, Iran
Not yet recruiting - verified May 2017

Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies

Conditions:   Lung Transplant; Complications, Mechanical;   Lung Transplant; Complications;   Bleeding;   Hemoptysis
Interventions:   Drug: Topical epinephrine;   Drug: Placebos
Sponsor:   University of Maryland
Not yet recruiting - verified May 2017

Vascular Effects of Alirocumab in Acute MI-Patients

Conditions:   Coronary Vessel;   Coronary Circulation;   Atheroma; Myocardial
Interventions:   Drug: Alirocumab 150 MG/ML;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   Regeneron Pharmaceuticals
Recruiting - verified May 2017

Impact of EMpagliflozin on Cardiac Function and Biomarkers of Heart Failure in Patients With Acute MYocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Empagliflozin 10 mg;   Drug: Placebo Oral Tablet
Sponsors:   Medical University of Graz;   United Arab Emirates University;   Medical University of Vienna;   Landeskrankenhaus Feldkirch;   Krankenhaus der Barmherzigen Brüder Linz;   Kepler University Hospital;   Paracelsus Medical University
Recruiting - verified May 2017

Biofreedom Prospective Multicenter Observational Registry

Conditions:   Coronary Artery Disease Aggravated;   Myocardial Ischemia;   Myocardial Infarction
Intervention:   Device: Biofreedom drug-coated stent
Sponsors:   Wonju Severance Christian Hospital;   Cordis Corporation
Not yet recruiting - verified May 2017

Outcomes in UK ACS Patients Prescribed Ticagrelor

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Completed - verified May 2017

Efficacy Study of Oral Nicorandil on Improving Microvascular Function in Female Non-obstructive Coronary Artery Disease (CAD) Subjects

Condition:   Non-obstructive Coronary Artery Disease
Interventions:   Drug: Nicorandil;   Drug: Standard treatment
Sponsor:   Merck KGaA
Recruiting - verified May 2017

Is the Current Threshold for Diagnosis of "Abnormality", Including Non ST Elevation Myocardial Infarction, Using Raised Highly Sensitive Troponin Appropriate for a Hospital Population? The CHARIOT Study

Condition:   Myocardial Infarction
Intervention:  
Sponsor:   University Hospital Southampton NHS Foundation Trust
Not yet recruiting - verified May 2017

Physical Activity Intervention for Patients With Reduced Physical Performance After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Other: physical activity intervention;   Other: standard of care
Sponsor:   University Hospital of Ferrara
Recruiting - verified May 2017

ASSessing the Effect of Anti-IL-6 Treatment in Myocardial Infarction: The ASSAIL-MI Trial

Conditions:   Coronary Disease;   Myocardial Infarction
Interventions:   Drug: Tocilizumab;   Drug: Sodium chloride 0.9%
Sponsors:   Oslo University Hospital;   St. Olavs Hospital;   South-Eastern Norway Regional Health Authority;   University of Oslo;   Norwegian University of Science and Technology
Recruiting - verified May 2017

Myocardial Ischemia and Transfusion

Conditions:   Myocardial Infarction;   Anemia
Intervention:   Biological: Red Blood Cell Transfusion
Sponsors:   Rutgers, The State University of New Jersey;   University of Pittsburgh;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2017

Evaluation of Coronary Artery Plaque Volume Progression/Regression and Safety of Alirocumab in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia

Conditions:   Hypercholesterolemia;   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553;   Drug: atorvastatin;   Drug: rosuvastatin;   Drug: fenofibrate;   Drug: bezafibrate;   Drug: ezetimibe;   Drug: antiplatelets;   Drug: anticoagulants
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified May 2017

CV Wizard: Does a Clinical Decision Support Tool Improve CVD Risk Factor Control in Safety Net Clinics?

Conditions:   Heart Attack;   Stroke;   Cardiovascular Diseases
Intervention:   Behavioral: CV WIZARD
Sponsors:   Kaiser Permanente;   Ochin, Inc.;   HealthPartners Institute
Not yet recruiting - verified May 2017

Mechanistic Effects of Colchicine in Patients With Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Drug: Colchicine 0.6 mg tablets
Sponsor:   New York University School of Medicine
Recruiting - verified May 2017

Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly

Conditions:   Cognitive Decline;   Stroke
Intervention:  
Sponsor:   University Hospital, Lille
Recruiting - verified May 2017

MGuard Stent and Microcirculation

Conditions:   Coronary Disease;   Coronary Artery Disease;   Coronary Atherosclerosis;   Cardiovascular Diseases
Interventions:   Device: MGuard stent;   Device: Drug eluting stent and bare metal stent
Sponsor:   University Hospital, Grenoble
Recruiting - verified May 2017

Effect of SNF472 on Progression of Cardiovascular Calicification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD)

Conditions:   Cardiovascular Diseases;   Cardiovascular Abnormalities;   Calcifications, Vascular;   Endstage Renal Disease;   ESRD;   Coronary Artery Calcification
Interventions:   Drug: SNF472;   Drug: Placebo
Sponsors:   Laboratoris Sanifit;   Clinipace Worldwide
Recruiting - verified May 2017

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY 1142524 in Patients After Acute Myocardial Infarction With Left-ventricular Dysfunction

Condition:   Myocardial Infarction
Interventions:   Drug: BAY1142524;   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified May 2017

Use of Different Diagnostic Coronary Catheters Over the Radial Access - the UDDC - Radial Trial

Condition:   Stable Coronary Heart Disease
Interventions:   Device: One-catheter concept;   Device: Standard catheter
Sponsor:   Charite University, Berlin, Germany
Completed - verified May 2017

Observational Study of Angiographic Coregistered Optical Coherence Tomography in Patients Undergoing PCI

Condition:   Coronary Artery Disease
Intervention:   Procedure: Percutaneous Coronary Intervention
Sponsor:   Charite University, Berlin, Germany
Completed - verified May 2017

Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI

Condition:   Acute Myocardial Infarction
Interventions:   Drug: LCZ696 (sacubitril/valsartan);   Drug: Ramipril;   Drug: Placebo of LCZ696;   Drug: Placebo of ramipril;   Drug: Valsartan;   Drug: Placebo of valsartan
Sponsor:   Novartis Pharmaceuticals
Recruiting - verified May 2017

Myocardial Infarction Register of the Saarland

Condition:   Myocardial Infarction
Intervention:  
Sponsors:   Stiftung Institut fuer Herzinfarktforschung;   Ministry of Social Affairs, Health, Women and Family of Saarland
Recruiting - verified May 2017

Reactive Oxygen Species Following Aortic Valve Replacement

Condition:   Aortic Stenosis
Intervention:  
Sponsor:   University Hospital Southampton NHS Foundation Trust
Recruiting - verified May 2017

Coronary Sinus Blood Sevoflurane and Desflurane Concentration and Lactate Changes in Patients Undergoing Heart Surgery

Conditions:   Myocardial Reperfusion Injury;   Heart Diseases;   Postoperative Complications
Intervention:   Biological: Blood samples
Sponsors:   University of Malaya;   University of Edinburgh
Not yet recruiting - verified August 2016

Randomized Anticoagulation Trial in Opcab (RATIO)

Condition:   Ischemic Heart Disease
Intervention:   Drug: Heparin
Sponsor:   Azienda Ospedaliera di Lecco
Recruiting - verified May 2017

LEADERS FREE II: BioFreedom™ Pivotal Study

Conditions:   Acute Coronary Syndrome;   High Bleeding Risk
Interventions:   Device: BioFreedom™ Drug Coated Coronary Stent System;   Drug: Dual Antiplatelet Therapy
Sponsor:   Biosensors Europe SA
Recruiting - verified May 2017

Hypertrophic Cardiomyopathy Pilot Study

Conditions:   Hypertrophic Cardiomyopathy;   Coronary Artery Disease
Intervention:   Other: Observational: Arrhythmogenic Substrate
Sponsor:   Oregon Health and Science University
Enrolling by invitation - verified May 2017

A Randomized Comparison of Clinical Outcomes Between Everolimus-eluting Bioresorbable Vascular Scaffold Versus Everolimus-eluting Metallic Stent in Long Coronary Lesions

Condition:   Coronary Artery Disease
Interventions:   Device: PCI with Absorb everolimus-eluting bioresorbable vascular scaffold;   Device: PCI with Xience everolimus-eluting metallic stent
Sponsor:   Yonsei University
Recruiting - verified May 2017

Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging(PARADIGM)

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   Yonsei University;   Montreal Heart Institute;   Hospital da Luz, Portugal;   University of California, Los Angeles;   Centro Cardiologico Monzino;   University of British Columbia;   German Heart Institute;   National Institute of Cardiology, Laranjeiras, Brazil;   Weill Medical College of Cornell University;   Cedars-Sinai Medical Center
Active, not recruiting - verified May 2017

Integrated Primary Care for Diabetes and Cardiovascular Disease

Conditions:   Diabetes Mellitus;   Hypertension;   Heart Failure;   Ischemic Heart Disease;   Cerebrovascular Disease
Interventions:   Behavioral: Outreach education training;   Behavioral: No outreach education training
Sponsors:   University of Sao Paulo General Hospital;   University of Sao Paulo;   Santa Catarina Federal University;   University of Cape Town;   Federal University of Bahia;   Medical Research Council, South Africa;   University of East Anglia
Recruiting - verified January 2017

Rehabilitation in the Home Setting for Older Adults In the Early Period After Myocardial Infarction

Condition:   Acute Myocardial Infarction (AMI)
Interventions:   Behavioral: Home-based physical therapy;   Behavioral: Usual Care
Sponsor:   New York University School of Medicine
Recruiting - verified May 2017

Evaluation of Plasma Non-coding RNAs as Biomarkers in Coronary Heart Disease

Condition:   Coronary Disease
Intervention:   Other: No intervention
Sponsor:   Tongji Hospital
Enrolling by invitation - verified May 2017

Quality and Safety of Initial Management for ST-segment Elevation Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Other: Daily practice care for patients with suspected of STEMI
Sponsors:   Centre Hospitalier de la Région d'Annecy;   University Hospital, Grenoble
Recruiting - verified May 2017

CT COMPARE: CT COronary Angiography to Measure PlAque REduction

Condition:   Cardiovascular Disease
Interventions:   Drug: Rosuvastatin;   Drug: Atorvastatin
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified April 3, 2017

EXpanded CELL ENdocardiac Transplantation (EXCELLENT)

Condition:   Acute Myocardial Infarction
Interventions:   Drug: PROTHERACYTES;   Device: Standard of Care (Percutaneous Transluminal Coronary Angioplasty and stent(s) implantation)
Sponsor:   CellProthera
Recruiting - verified October 2016

Does Ranolazine Decrease Biomarkers of Myocardial Damage in Diabetics

Conditions:   Silent Myocardial Ischemia;   Type 2 Diabetes
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsor:   Walter Reed National Military Medical Center
Withdrawn - verified May 2017

The Use of Ambulatory Blood Pressure Monitors to Assess Angiotensin Converting Enzyme Inhibitors

Condition:   Hypertension, Resistant to Conventional Therapy
Interventions:   Drug: Equivalent dose enalapril;   Drug: Equivalent dose lisinopril
Sponsor:   Memorial Health University Medical Center
Recruiting - verified May 2017

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified May 2017

Atorvastatin Effectiveness and Safety in Cardiology Patients in Real World Setting

Condition:   Coronary Artery Disease, Hypercholesterolemia, Hypertension
Intervention:   Other: No intervention
Sponsor:   Pfizer
Recruiting - verified May 2017

Boston Scientific COMET Wire Validation Study

Condition:   Stable Angina
Interventions:   Device: Boston Scientific Pressure Wire;   Device: Validation of Boston Scientific pressure wire
Sponsors:   University Hospital Southampton NHS Foundation Trust;   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Boston Scientific Corporation
Completed - verified May 2017

ComparisoN of ticAgrelor vs. Clopidogrel in endoTHeliAl Function of COPD patieNts

Conditions:   Coronary Artery Disease;   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Aspirin 100 mg;   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   University Hospital of Ferrara
Completed - verified May 2017

Clinical Study of Extra-Corporal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction

Condition:   Cardiogenic Shock
Intervention:   Device: Extra-Corporal Life Support (ECLS)
Sponsor:   Klinikum der Universitaet Muenchen
Recruiting - verified May 2017

Risk Stratification for Coronary Artery Disease With Type 2 Diabetic Patients

Condition:   Coronary Arteriosclerosis
Intervention:  
Sponsors:   Acarix;   Steno Diabetes Center;   Rigshospitalet, Denmark
Completed - verified May 2017

COOL AMI EU Pilot Trial to Assess Cooling as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Device: Cooling + PCI;   Device: PCI only
Sponsor:   ZOLL Circulation, Inc., USA
Active, not recruiting - verified May 2017

Copeptin Registry (proCORE) Biomarkers in Cardiology (BIC)-19

Condition:   Acute Myocardial Infarction
Intervention:   Procedure: Routine management observation
Sponsor:   Charite University, Berlin, Germany
Completed - verified May 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified May 2017

Medtronic Resolute Onyx 2.0 mm Clinical Study

Condition:   Coronary Artery Disease
Intervention:   Device: Resolute Onyx Stent - 2.0 mm
Sponsor:   Medtronic Vascular
Active, not recruiting - verified May 2017

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified May 2017

COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Exenatide;   Other: Remote Ischemic Conditioning (RIC);   Drug: Placebo
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Recruiting - verified May 2017

Bivalirudin vs Heparin in NSTEMI and STEMI in Patients on Modern Antiplatelet Therapy in SWEDEHEART

Conditions:   ST-segment Elevation Myocardial Infarction;   Non ST-segment Elevation Myocardial Infarction
Interventions:   Drug: bivalirudin;   Drug: Heparin
Sponsors:   Uppsala University;   Lund University
Completed - verified May 2017

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified May 2017

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified May 2017

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2017

Sampling P2Y12 Receptor Inhibition With Prasugrel and Ticagrelor in Patients Submitted to Thrombolysis

Conditions:   Acute Coronary Syndrome;   Platelet Function
Interventions:   Drug: Prasugrel;   Drug: Ticagrelor
Sponsor:   Federal University of São Paulo
Completed - verified May 2017

Chemoreflex Control of Sympathetic Activity in Patients With Coronary Artery Disease

Conditions:   Coronary Artery Disease (CAD);   Obstructive Sleep Apnea (OSA)
Intervention:   Other: Aerobic exercise training
Sponsor:   University of Sao Paulo General Hospital
Recruiting - verified May 2017

Comprehensive Lifestyle Modification for Patients With Hypertension and Metabolic Syndrome: a Multicenter Randomized Controlled Trial

Conditions:   Hypertension;   Metabolic Syndrome
Interventions:   Behavioral: Comprehensive Lifestyle Modification;   Behavioral: DASH
Sponsors:   Universität Duisburg-Essen;   Kliniken Essen-Mitte;   Immanuel Hospital Berlin, Berlin, Germany;   Charite University, Berlin, Germany;   University of Witten/Herdecke
Completed - verified May 2017

Swedish Drug-elution Trial in Peripheral Arterial Disease

Conditions:   Peripheral Arterial Disease;   Critical Limb Ischemia;   Intermittent Claudication
Interventions:   Procedure: Revascularization with drug-eluting technology;   Procedure: Revascularization without drug-eluting technology;   Device: drug-coated balloons and/or drug-eluting stents
Sponsors:   Sahlgrenska University Hospital, Sweden;   The Swedish Research Council;   Swedish Heart Lung Foundation;   Uppsala University;   The Swedish National Registry for Vascular Surgery
Recruiting - verified May 2017

Essential Hypotension and Allostasis Registry

Conditions:   Blood Pressure;   Depression;   Panic Attack;   Fibromyalgia;   POTS;   Inappropriate Sinus Tachycardia;   Coronary Heart Disease;   Acute Coronary Syndrome (ACS);   Acute Myocardial Infarction (AMI);   Cerebrovascular Disease (CVD);   Transient Ischemic Attack (TIA);   Atrial Fibrillation;   Diabetes Mellitus;   Cancer;   Systolic Heart Failure;   Diastolic Heart Failure;   Chronic Fatigue Syndrome;   Syncope;   Vasovagal Syncope
Intervention:  
Sponsor:   CES University
Recruiting - verified May 2017

COOL-AMI EU Case Series Clinical Study

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   ZOLL Circulation, Inc., USA
Recruiting - verified May 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified May 2017

MRI Study After Arterial Switch Operation in Patients With Transposition of the Great Arteries

Conditions:   Transposition of Great Vessels;   Surgery
Interventions:   Other: 3 tesla magnetic resonance imaging findings; coronary artery status;   Other: 3 tesla magnetic resonance imaging findings; ventricular function and morphology
Sponsor:   Oslo University Hospital
Completed - verified May 2017

OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA

Conditions:   Coronary Heart Disease;   Diabetes;   Vascular Lesions;   Chronic Total Occlusion of Coronary Artery;   Restenosis
Intervention:   Device: TAXUS™ Element long stent
Sponsors:   Centre Chirurgical Marie Lannelongue;   Cochin Hospital;   Centre Hospitalier de La Rochelle;   University Hospital, Limoges;   Hôpital de la Timone;   Centre Hospitalier Universitaire de Nice;   Centre Hospitalier de PAU;   Rangueil Hospital;   Versailles Hospital
Active, not recruiting - verified May 2017

Study to Determine the Effect of Repeated Administration of Diltiazem on the Pharmacokinetics of Darapladib (Sb-480848).

Condition:   Atherosclerosis
Interventions:   Drug: Darapladib;   Drug: Diltiazem
Sponsor:   GlaxoSmithKline
Completed - verified May 2017

Effects of a Comprehensive Sexual Rehabilitation Programme in Heart Patients

Conditions:   Ischaemic Heart Disease;   Cardiac Arrhythmia;   Sexual Dysfunction
Interventions:   Other: sexual rehabilitation;   Other: Usual care
Sponsors:   Rigshospitalet, Denmark;   Bispebjerg Hospital
Completed - verified May 2017

Improvement Assessment of Coronary Flow Dysfunction Using Fundamental Fluid Dynamics

Condition:   Coronary Artery Disease
Intervention:   Procedure: Cardiac PET, Coronary catheterization
Sponsor:   University of Cincinnati
Active, not recruiting - verified May 2017

Administration of AdVEGF-All6A+ to Myocardium of Individuals With Diffuse CAD Via Minimally Invasive Surgery

Condition:   Coronary Artery Disease
Interventions:   Biological: AdVEGF-All6A+;   Biological: AdNull
Sponsor:   Weill Medical College of Cornell University
Not yet recruiting - verified May 2017

Clinical Implication of 3-vessel Fractional Flow Reserve (FFR)

Condition:   Multivessel Coronary Artery Disease
Intervention:  
Sponsors:   Seoul National University Hospital;   Samsung Medical Center;   Keimyung University Dongsan Medical Center;   Inje University;   Fu Wai Hospital, Beijing, China;   The First Affiliated Hospital with Nanjing Medical University;   Second Affiliated Hospital, School of Medicine, Zhejiang University;   Guangdong General Hospital;   Tokyo medical college hospital, Japan;   Kokura memorial hospital, Japan;   Gifu heart center, Japan;   Aichi Medical University;   Wakayama Medical University;   Queen Mary Hospital, Hong Kong;   United Christian Hospital;   National University Heart Centre, Singapore;   National Taiwan University Hospital;   Nagoya Daini Nesseki Hospital;   Ulsan University Hospital;   Ajou University School of Medicine
Active, not recruiting - verified May 2017

Stem Cell Injection to Treat Heart Damage During Open Heart Surgery

Conditions:   Heart Disease;   Ischemic Heart Disease;   Coronary Artery Disease;   Coronary Artery Disease (CAD)
Intervention:   Other: Cell Therapy
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   NIH Heart Center at Suburban Hospital
Active, not recruiting - verified May 16, 2017

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: bicalutamide;   Drug: buserelin;   Drug: flutamide;   Drug: goserelin acetate;   Drug: leuprolide acetate;   Drug: orteronel;   Drug: triptorelin
Sponsors:   Radiation Therapy Oncology Group;   National Cancer Institute (NCI);   NRG Oncology
Active, not recruiting - verified May 2017

Diagnostic Accuracy of Cardiac CT Perfusion Compared to PET Imaging

Conditions:   Myocardial Ischemia;   Coronary Artery Disease;   Myocardial Infarction
Intervention:  
Sponsor:   University of Washington
Recruiting - verified May 2017

Drug Use Investigation for IMIGRAN Tablet

Condition:   Migraine Disorders
Intervention:   Drug: Sumatriptan
Sponsor:   GlaxoSmithKline
Completed - verified May 2017

The Glucagon Stimulation Test for Evaluation of Adult Growth Hormone Deficiency and Adrenocorticotropic Axis

Conditions:   Adult Growth Hormone Deficiency;   Hypothalamic-pituitary Disorders
Interventions:   Procedure: Glucagon stimulation test and insulin tolerance test;   Procedure: glucagon stimulation test and insulin tolerance test
Sponsors:   The Cleveland Clinic;   Massachusetts General Hospital;   Allegheny Endocrinology Associates;   Oregon Health and Science University
Completed - verified May 2017

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Conditions:   Heart; Dysfunction Postoperative, Cardiac Surgery;   Genetic Predisposition to Disease;   Atrial Fibrillation;   Myocardial Infarction;   Heart Failure
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   Texas Heart Institute;   University of Texas Southwestern Medical Center
Recruiting - verified May 2017

Post Ten Year Follow up Assessment of a Phase I Trial of Angiogenic Gene Therapy

Conditions:   Coronary Artery Disease;   Ischemia
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   Stony Brook University
Completed - verified May 2017

Integrated Dual Exercise and Lexiscan Positron Emission Tomography: IDEALPET

Condition:   Coronary Artery Disease
Interventions:   Drug: Exercise plus Regadenoson (Lexercise);   Drug: Regadenoson (Lexiscan)
Sponsor:   Brigham and Women's Hospital
Active, not recruiting - verified May 2017

Relation Between Aldosterone and Cardiac Remodeling After Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Biological: blood sample;   Procedure: MRI;   Procedure: echocardiography;   Biological: urine sample;   Procedure: pulmonary echography;   Procedure: vascular check;   Procedure: renal echography
Sponsor:   Central Hospital, Nancy, France
Active, not recruiting - verified May 2017

IK-1001 (Sodium Sulfide (Na2S) for Injection) in Subjects With Acute ST-Segment Elevation Myocardial Infarction

Condition:   ST-Segment Elevation Myocardial Infraction
Interventions:   Drug: Sodium Sulfide (Na2S) for Injection;   Drug: Placebo
Sponsor:   Mallinckrodt
Withdrawn - verified May 2017

Prospective Observational Epidemiologic Study of Maraviroc's Safety

Condition:   Human Immunodeficiency Virus
Interventions:   Drug: Maraviroc along with an optimized background antiretroviral drug regimen;   Drug: Optimized background antiretroviral drug regimen without maraviroc
Sponsors:   ViiV Healthcare;   Pfizer
Active, not recruiting - verified May 2017

Prevention of Coronary Heart Disease in Morbidly Obese Patients

Conditions:   Morbid Obesity;   Hypertension;   Type 2 DM;   Obstructive Sleep Apnea;   Osteoarthrosis
Interventions:   Procedure: Bariatric Surgery;   Behavioral: Conservative Treatment:
Sponsors:   The Hospital of Vestfold;   Oslo University Hospital
Active, not recruiting - verified May 2017

ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

Conditions:   Cardiovascular Disease;   Coronary Artery Calcification
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified May 17, 2017

Safety of SCH 530348 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention (Study P03573)

Conditions:   Arterial Obstructive Diseases;   Coronary Disease
Intervention:   Drug: SCH 530348
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified May 2017

Which Therapy for Acute Heart Attacks? (The WEST Study)

Condition:   Myocardial Infarction
Interventions:   Drug: tenecteplase;   Drug: enoxaparin;   Drug: clopidogrel;   Procedure: percutaneous coronary intervention
Sponsors:   University of Alberta;   Hoffmann-La Roche;   Sanofi;   Eli Lilly and Company
Completed - verified July 2005

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Peripheral Artery Disease
Intervention:   Procedure: MRI
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 19, 2017

Epidemiology: Oxidative Stress and Early Atherosclerosis

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Atherosclerosis;   Coronary Arteriosclerosis
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Northwestern University;   Kaiser Permanente;   University of Alabama at Birmingham
Active, not recruiting - verified May 2017