Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Tele - Cardiac Rehabilitation - Providing Secondary Prevention and Supervised Exercise Without Boundaries of Time and Space - PILOT 1

Condition:   Coronary Artery Disease
Intervention:   Behavioral: Tele Cardiac Rehabilitation
Sponsor:   Sheba Medical Center
Recruiting - verified July 2017

A Case-control Study to Assess the Association Between Facial Characteristics and Coronary Artery Diseases

Condition:   Coronary Artery Disease
Intervention:   Other: Facial characteristics
Sponsor:   China National Center for Cardiovascular Diseases
Recruiting - verified July 2017

The Registry Study to Compare the Cardiopulmonary Exercise Test Parameters Before and After Cardiac Rehabilitation in Patients With Chronic Total Occlusion of the Coronary Arteries

Conditions:   Coronary Artery Disease;   Total Occlusion of Coronary Artery
Intervention:   Behavioral: cardiac rehabilitation
Sponsor:   Seung-Jung Park
Not yet recruiting - verified July 2017

Clinical Trial on Safety and Efficacy of Drug-coated Balloon in Treatment of Coronary Bifurcation Lesions

Condition:   Coronary Disease
Interventions:   Device: Paclitaxel DCB;   Device: DES
Sponsor:   Beijing Hospital
Not yet recruiting - verified July 2017

Baduanjin Exercise for Patients With Chronic Heart Failure on Phase II Cardiac Rehabilitation

Condition:   Rehabilitation With CHF; NYHA Class I or II
Interventions:   Behavioral: Baduanjin exercise;   Behavioral: Routine rehabilitation group
Sponsor:   Xiyuan Hospital of China Academy of Chinese Medical Sciences
Recruiting - verified July 2017

FFRangio Accuracy vs. Standard FFR

Condition:   Coronary Artery Disease
Intervention:   Device: FFRangio
Sponsors:   CathWorks Ltd.;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2017

Pragmatic Trial Comparing Symptom-Oriented Versus Routine Stress Testing in High-Risk Patients Undergoing Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease With Myocardial Infarction
Interventions:   Diagnostic Test: routine stress testing;   Diagnostic Test: symptom oriented stress testing
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2017

Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)

Conditions:   Cardiovascular Diseases;   Diabetes;   Metabolic Syndrome;   Cancer;   Inflammatory Disease;   Atherosclerosis;   Cognitive Decline;   Liver Diseases;   Death;   Pain, Chronic;   Depression;   Infection;   Chronic Disease
Intervention:  
Sponsor:   University of Eastern Finland
Active, not recruiting - verified July 2017

Effect of Polyvitaminics (Pyridoxine Hydrochloride, Folic Acid and Cyanocobalamin) in the Concentration of Homocysteine and Lipid Profile in Postmenopausal Women: a Randomized Controlled, Double-blind Clinical Trial

Conditions:   Menopause;   Dyslipidemias;   Homocystinaemia
Interventions:   Drug: Tenavit®;   Drug: Placebo Oral Tablet
Sponsor:   Casa de Saúde santa Marcelina
Completed - verified July 2017

Heart Function in Patients Assessed for Sleep Apnoea

Conditions:   Heart Failure With Preserved Ejection Fraction;   Sleep Disordered Breathing;   Heart Failure With Normal Ejection Fraction;   Obstructive Sleep Apnea;   Central Sleep Apnea;   Heart Failure
Intervention:  
Sponsors:   Imperial College London;   Royal Brompton & Harefield NHS Foundation Trust;   ResMed
Not yet recruiting - verified July 2017

Randomization of Single vs Multiple Arterial Grafts

Conditions:   Coronary Artery Disease;   Heart Diseases
Interventions:   Procedure: Single arterial graft;   Procedure: Multiple arterial grafting
Sponsors:   Weill Medical College of Cornell University;   Sunnybrook Health Sciences Centre;   Duke University;   The Cleveland Clinic;   Heartcenter Leipzig GmbH;   University of Rotterdam, The Netherlands;   Maastricht University Medical Center;   University College Hospital Galway;   Ottawa Heart Institute Research Corporation;   University of Toledo Health Science Campus
Not yet recruiting - verified July 2017

Study for Evaluation of Newly Onset Chest Pain and Rapid Diagnosis of Myocardial Necrosis

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Completed - verified July 2017

Early Initiation of Post Sternotomy CArdiac Rehabilitation

Conditions:   Coronary Artery Disease;   Aortic Valve Disease;   Mitral Valve Disease
Intervention:   Behavioral: timing of initiation of cardiac rehabilitation
Sponsors:   University Hospitals Coventry and Warwickshire NHS Trust;   Coventry University
Recruiting - verified July 2017

Evaluation of the Opsens Fractional Flow Reserve (FFR) Wire as a "Work Horse" Wire

Condition:   Coronary Artery Disease
Intervention:   Diagnostic Test: Fractional Flow Reserve
Sponsor:   Central Arkansas Veterans Healthcare System
Recruiting - verified July 2017

Induced Myocardial Ischemia: a Serial Troponin T and Troponin I Measurements

Conditions:   Acute Coronary Syndrome;   Cardiac Ischemia
Intervention:   Other: coronary occlusion
Sponsor:   Herlev Hospital
Recruiting - verified July 2017

A2 AR as a Novel Biomarkers for Physician Decision-making Improvement Evaluation's Patients With Suspected Acute Coronary Syndrome But Negative Troponin.

Condition:   Acute Coronary Syndrome
Intervention:   Biological: blood samples
Sponsor:   Assistance Publique Hopitaux De Marseille
Not yet recruiting - verified July 2017

ANti-Oxidant in Variant Angina (ANOVA) Trial

Condition:   Variant Angina
Interventions:   Drug: Vitamin C and Vitamin E;   Drug: Statin;   Drug: Standard medication for variant angina
Sponsor:   Seoul National University Hospital
Recruiting - verified July 2017

A Pharmacist-Led Hospital-Based Intervention to Support Medication Adherence Following Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:   Behavioral: Intervention cohort ('after' group)
Sponsors:   King's College London;   Guy's and St Thomas' NHS Foundation Trust
Not yet recruiting - verified June 2017

Red Meat, Increased Iron Load and CVD Risk

Conditions:   Myocardial Infarction;   Stroke;   Cardiovascular Mortality
Intervention:   Other: No intervention assigned, this is an observational study.
Sponsor:   German Cancer Research Center
Completed - verified July 2017

Subclinical Cardiovascular Disease in Psoriatic Disease

Conditions:   Cardiovascular Diseases;   Myocardial Infarction;   Atherosclerotic Cardiovascular Disease;   Thrombotic Vascular Disease
Intervention:   Drug: Aspirin and/or Atorvastatin
Sponsor:   New York University School of Medicine
Not yet recruiting - verified July 2017

HOW To Optimally Implant BioResorbable Scaffold - Intravascular Imaging Versus Quantitative Coronary Angiography Guidance

Condition:   Coronary Stenosis
Interventions:   Device: quantitative coronary angiography guided Bioresorbable scaffold implantation;   Device: imaging guided Bioresorbable scaffold implantation
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2017

Evaluation of Vascular Regeneration After a Drug Eluting Stent Implantation

Condition:   Stable Angina
Intervention:  
Sponsors:   Hospital San Carlos, Madrid;   Instituto de Salud Carlos III
Completed - verified July 2017

Brilinta Clinical Experience Investigation

Condition:   Acute Coronary Syndrome, Old Myocardial Infarction
Intervention:  
Sponsor:   AstraZeneca
Not yet recruiting - verified July 2017

Watermelon Focused Dietary Inflammatory Index Intervention

Conditions:   Inflammation;   Diet Modification
Interventions:   Behavioral: DII-Based Counseling System;   Behavioral: general health education control
Sponsors:   Connecting Health Innovation;   National Watermelon Promotion Board
Recruiting - verified July 2017

Cardiac Rehabilitation in Patients With Refractory Angina

Condition:   Refractory Angina
Intervention:   Behavioral: Cardiac Rehabilitation
Sponsors:   Hospital Israelita Albert Einstein;   Fundação de Amparo à Pesquisa do Estado de São Paulo;   Instituto do Coracao
Recruiting - verified January 2017

Transcriptome Study of Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Beijing Institute of Heart, Lung and Blood Vessel Diseases
Recruiting - verified July 2017

The Incidence, Effect and Persistence of Fragmented-QRS, in Patients Presenting With ST-Elevation Myocardial Infarction

Condition:   ST Elevation Myocardial Infarction
Intervention:  
Sponsor:   The Royal Wolverhampton Hospitals NHS Trust
Not yet recruiting - verified May 2017

Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis

Conditions:   Pulse Wave;   Aortic Stenosis
Interventions:   Other: Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction;   Other: Control group without heart disease
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified July 2017

Coronary Anatomy Study and Times Since the Onset of Acute Myocardial Infarction Symptoms in Women Until the Opening of the Artery (TAPAC Study)

Condition:   Myocardial Infarction
Intervention:   Other: Non intervention
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Not yet recruiting - verified April 2017

ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arrest

Conditions:   Cardiac Arrest Due to Underlying Cardiac Condition;   Ventricular Fibrillation;   Cardiopulmonary Arrest With Successful Resuscitation
Interventions:   Procedure: Initial CCL admission;   Diagnostic Test: Initial ICU admission
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting - verified July 2017

Physiologic Assessment of Coronary Stenosis Following PCI

Conditions:   Coronary Artery Disease;   Coronary Stenosis;   Angina, Unstable;   Angina, Stable
Intervention:   Diagnostic Test: iFR pullback
Sponsors:   Volcano Corporation;   Duke Clinical Research Institute;   Cardiovascular Research Foundation, New York
Recruiting - verified July 2017

Multicenter Cohort of STEMI Patients

Condition:   STEMI - ST Elevation Myocardial Infarction
Interventions:   Biological: Blood sampling;   Procedure: ECG;   Device: MRI;   Other: Quality of life questionnaire
Sponsor:   Hospices Civils de Lyon
Recruiting - verified February 2017

Efficacy of Angiolite Stent vs a Second-generation Drug-eluting Stent Xience for Percutaneous Coronary Intervention

Conditions:   Coronary Artery Disease;   Drug-eluting Stent
Interventions:   Device: Angiolite;   Device: Xience
Sponsor:   Cardiva2 S.L.
Active, not recruiting - verified July 2017

Determining Change in Cardiovascular and Metabolic Risks in Patients With Chronic Phase Chronic Myeloid Leukemia Receiving BCR-ABL Tyrosine Kinase Inhibitor First-Line Therapy in the United States

Condition:   Chronic Phase Chronic Myeloid Leukemia
Intervention:  
Sponsor:   Bristol-Myers Squibb
Recruiting - verified July 2017

Molecular Investigation of Genetic Factors in CArDiovascular Diseases Using an BIOresource of Healthy Volunteers

Condition:   Cardiovascular Diseases
Interventions:   Other: Eligibility and lifestyle restrictions check.;   Other: Medical history, demographic and lifestyle factors;   Other: Anthropometric measurements: height, weight, and body fat;   Other: Blood pressure and heart rate;   Other: Forearm blood flow: Visit 1 (EDNRA);   Other: Forearm blood flow: Visit 2 (EDNRA);   Other: Blood biochemistry (PNPLA3);   Other: Blood EPCR function (PROCR);   Other: Blood platelet coagulation and function (PROCR);   Other: Blood endothelial permeability (PROCR);   Other: Blood leukocyte-endothelium adhesion (PROCR);   Other: Baseline Venepuncture (PNPLA3, Visit 1);   Other: Deuterium water - Loading dose 1 (PNPLA3, Visit 1);   Other: Deuterium water - Loading dose 2 (PNPLA3, Visit 1);   Other: Energy-balanced dinner (PNPLA3, Visit 1);   Other: Fasting venepuncture (PNPLA3, Visit 2);   Other: Deuterium water - Maintenance dose (PNPLA3, Visit 2);   Other: Consumption of high carbohydrate meal (PNPLA3, Visit 2);   Other: Postprandial Venepuncture (PNPLA3, Visit 2);   Other: Venepuncture (PROCR)
Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   University of Cambridge
Not yet recruiting - verified July 2017

Efficacy Study of Oral Nicorandil on Improving Microvascular Function in Female Non-obstructive Coronary Artery Disease (CAD) Subjects

Condition:   Non-obstructive Coronary Artery Disease
Interventions:   Drug: Nicorandil;   Drug: Standard treatment
Sponsor:   Merck KGaA
Recruiting - verified July 2017

Prognostic Value of Plasma DPP4 Activity in ST-elevation Myocardial Infarction Patients

Conditions:   Coronary Angiography;   Dipeptidyl Peptidase 4
Intervention:   Diagnostic Test: plasma DPP4 activity
Sponsor:   Chinese PLA General Hospital
Completed - verified July 2017

Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen

Conditions:   High Bleeding Risk;   Coronary Artery Disease;   PCI
Interventions:   Drug: Aspirin;   Drug: P2Y12 inhibitor
Sponsors:   ECRI bv;   Cardialysis B.V.;   European Cardiovascular Research Center;   University of Bern;   Terumo Medical Corporation
Recruiting - verified July 2017

Metabolomic Profile of Patients Undergoing Myocardial Perfusion SPECT

Condition:   Ischemic Heart Disease
Intervention:   Other: Non intervention
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Recruiting - verified March 2017

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY 1142524 in Patients After Acute Myocardial Infarction With Left-ventricular Dysfunction

Condition:   Myocardial Infarction
Interventions:   Drug: BAY1142524;   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified July 2017

Effects of High-intensity Inspiratory Muscle Training in Patients Undergoing Coronary Artery Bypass Grafting Surgery

Condition:   Complications Due to Coronary Artery Bypass Graft
Intervention:   Device: High-intensity IMT + combined exercise
Sponsor:   Universidade Federal de Santa Maria
Completed - verified July 2017

Thin Strut Sirolimus-eluting Stent in All Comers Population vs Everolimus-eluting Stent

Condition:   Coronary Stenosis
Interventions:   Device: SUPRAFLEX;   Device: XIENCE
Sponsors:   ECRI bv;   Sahajanand Medical Technologies Pvt. Ltd.
Active, not recruiting - verified July 2017

The Box: Using Smart Technology to Improve One-year Outcome of Myocardial Infarction Patients

Condition:   Myocardial Infarction
Intervention:   Other: The Box
Sponsor:   Leiden University Medical Center
Recruiting - verified July 2017

Studying Partial-agonists for Ethanol and Tobacco Elimination in Russians With HIV (St PETER HIV)

Conditions:   HIV Infection;   Alcohol Use;   Smoking
Interventions:   Drug: Varenicline;   Drug: Cytisine;   Drug: Nicotine Replacement Therapy;   Drug: Varenicline Placebo;   Drug: Cytisine Placebo;   Drug: Nicotine Replacement Therapy Placebo
Sponsors:   Boston Medical Center;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified July 2017

IRIS-Synergy Cohort in the IRIS-DES Registry

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Jung-min Ahn;   CardioVascular Research Foundation, Korea
Recruiting - verified July 2017

A Randomized, Pharmacodynamic Comparison of Low Dose Ticagrelor to Clopidogrel in Patients With Prior Myocardial Infarction

Conditions:   Myocardial Infarction;   Diabetes Mellitus;   Renal Disease;   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsors:   University of Patras;   AstraZeneca
Completed - verified July 2017

Colchicine in Percutaneous Coronary Intervention

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome
Intervention:   Drug: Colchicine vs Placebo
Sponsors:   VA Office of Research and Development;   New York University School of Medicine
Recruiting - verified July 2017

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified July 2017

Atorvastatin Effectiveness and Safety in Cardiology Patients in Real World Setting

Condition:   Coronary Artery Disease, Hypercholesterolemia, Hypertension
Intervention:   Other: No intervention
Sponsor:   Pfizer
Recruiting - verified July 2017

Impact on Public HEalth of a Network in Acute Myocardial Infarction Care

Conditions:   Myocardial Infarction;   Acute Coronary Syndrome
Intervention:  
Sponsors:   Complexo Hospitalario Universitario de A Coruña;   Hospital Universitario Lucus Augusti;   Hospital Arquitecto Marcide
Completed - verified July 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified July 2017

Effects of Ivabradine in Patients With Stable Coronary Artery Disease Without Clinical Heart Failure

Condition:   Coronary Artery Disease
Interventions:   Drug: Ivabradine;   Drug: Placebo
Sponsor:   Servier
Completed - verified July 2017

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified July 2017

Inflammation and Coronary Endothelial Function

Condition:   Coronary Artery Disease
Interventions:   Drug: Methotrexate;   Drug: Colchicine;   Drug: Placebo
Sponsors:   Johns Hopkins University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2017

Shockwave Coronary Lithoplasty Study

Condition:   Coronary Stenosis
Intervention:   Device: Shockwave Coronary Lithoplasty System
Sponsors:   Shockwave Medical, Inc.;   Yale Cardiovascular Research Group;   Massachusetts General Hospital;   Pacific Clinical Research Group
Completed - verified July 2017

Evaluation of the Utility of Telemetry in Patients Admitted for Chest Pain Who Are at Low Risk for Acute Coronary Syndrome

Conditions:   Chest Pain;   Telemetry;   Acute Coronary Syndrome;   Health Care Resource Utilization
Interventions:   Other: No Telemetry Monitoring;   Device: Telemetry Monitoring
Sponsors:   Carilion Clinic;   Johns Hopkins University;   University of Maryland;   Virginia Commonwealth University;   MedStar Health;   Virginia Tech Carilion Research Institute
Completed - verified July 2017

Prospective International Study of Coronary Subtraction Using 320 Detector Row CT (CorSub)

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 7, 2017

The Preventive Implantation of Bioresorbable Vascular Scaffold on Functionally Insignificant Stenosis With Vulnerable Plaque Characteristics

Conditions:   Coronary Artery Disease;   Plaque, Atherosclerotic
Interventions:   Device: Bioresorbable Vascular Scaffold;   Drug: Optimal Medical treatment
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified July 2017

BIO monitorinG in Patients With Preserved Left ventricUlar Function AfteR Diagnosed Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:   Device: BioMonitor
Sponsor:   Biotronik SE & Co. KG
Recruiting - verified July 2017

Minority Health Genomics and Translational Research Bio-Repository Database (MH-GRID)-2.0

Condition:   Hypertension
Intervention:  
Sponsors:   National Human Genome Research Institute (NHGRI);   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified January 24, 2017

Perioperative Assessment of Right Ventricular Function and Venous Return in Patients With Epithelial Ovarian Cancer Undergoing Cytoreductive Surgery (Gyn Right) - Pilot Study

Condition:   Right Ventricular Function and Venous Return
Intervention:  
Sponsor:   Charite University, Berlin, Germany
Withdrawn - verified July 2017

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified July 2017

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2017

"Preventing Cardiovascular Ischemic Events and Arresting Their Consequences in Type 2 Diabetic Population

Conditions:   Type2 Diabetes Mellitus;   Microangiopathy;   Non Alcoholic Fatty Liver Disease;   Coronary Artery Disease;   Cerebrovascular Disease;   Acute Coronary Syndrome/ Myocardial Infarction;   Ictus
Intervention:  
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Active, not recruiting - verified March 2017

Paraoxonase and HDL Qualities in Glycaemia and Inflammation

Conditions:   Diabetes Mellitus;   Bariatric Surgery Candidate
Intervention:  
Sponsors:   Central Manchester University Hospitals NHS Foundation Trust;   British Heart Foundation;   Juvenile Diabetes Research Foundation
Recruiting - verified July 2017

Absorb IV Randomized Controlled Trial

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: Absorb BVS;   Device: XIENCE
Sponsor:   Abbott Vascular
Active, not recruiting - verified July 2017

Colchicine in Vascular Inflammation Assessed With PET Imaging

Condition:   Atherosclerotic Vascular Disease
Interventions:   Drug: Colchicine;   Drug: Placebo
Sponsor:   Montreal Heart Institute
Completed - verified July 2017

Outcomes of Angiotensin Converting Enzyme Inhibitor Management Strategies Prior to Coronary Artery Bypass

Condition:   Coronary Artery Disease
Interventions:   Drug: ACE/ARB continuation;   Drug: ACE/ARB withdrawal
Sponsor:   University of Alberta
Active, not recruiting - verified July 2017

Aortic Valve and Root Measurements Under Real-Time 3-Dimensional Visualization During Angiography

Conditions:   Coronary Artery Disease;   Aortic Stenosis
Intervention:   Radiation: Real-time 3-dimensional DynaCT
Sponsor:   New York University School of Medicine
Completed - verified July 2017

Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in Europe

Conditions:   Coronary Artery Disease;   Myocardial Infarction;   Dilated Cardiomyopathy;   Implantable Defibrillator User
Intervention:  
Sponsor:   University Medical Center Goettingen
Recruiting - verified July 2017

IRIS-PREMIER REGISTRY

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Coronary Disease;   Heart Diseases
Intervention:   Device: Promus PREMIER
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea;   Boston Scientific Korea Co. Ltd
Active, not recruiting - verified July 2017

Ventricular Remodeling and Heart Failure After Myocardial Infarction: A Community Study

Conditions:   Heart Failure;   Myocardial Infarction
Intervention:  
Sponsor:   Mayo Clinic
Recruiting - verified July 2017

Essential Hypotension and Allostasis Registry

Conditions:   Blood Pressure;   Depression;   Panic Attack;   Fibromyalgia;   POTS;   Inappropriate Sinus Tachycardia;   Coronary Heart Disease;   Acute Coronary Syndrome (ACS);   Acute Myocardial Infarction (AMI);   Cerebrovascular Disease (CVD);   Transient Ischemic Attack (TIA);   Atrial Fibrillation;   Diabetes Mellitus;   Cancer;   Systolic Heart Failure;   Diastolic Heart Failure;   Chronic Fatigue Syndrome;   Syncope;   Vasovagal Syncope
Intervention:  
Sponsor:   CES University
Recruiting - verified July 2017

The TRansendocardial Stem Cell Injection Delivery Effects on Neomyogenesis STudy (The TRIDENT Study)

Conditions:   Chronic Ischemic Left Ventricular Dysfunction;   Myocardial Infarction
Intervention:   Biological: Allogeneic hMSCs
Sponsors:   Joshua M Hare;   The EMMES Corporation
Active, not recruiting - verified July 2017

Comparison of Depression Identification After Acute Coronary Syndrome: Quality of Life and Cost Outcomes

Conditions:   Acute Coronary Syndrome;   Depressive Symptoms
Interventions:   Other: Cognitive Behavioral Therapy (CBT);   Drug: Antidepressant Medication;   Other: Standard Care;   Other: Depressive symptom screener;   Other: No intervention
Sponsors:   Columbia University;   National Heart, Lung, and Blood Institute (NHLBI);   Duke University;   HealthPartners Institute;   Kaiser Foundation Research Institute
Active, not recruiting - verified July 2017

Study to Assess the Safety and Cardiovascular Effects of Autologous Adipose-Derived Stromal Cells Implantation In Patients During the Acute Recovery Phase of ST-Elevation Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:   Procedure: ASC isolation and implantation
Sponsors:   Ageless Regenerative Institute;   Instituto de Medicina Regenerativa, S.A. de C.V.
Withdrawn - verified March 2017

Are Serial Electrocardiograms Additive to SeriAl Second-generations Troponins in Predicting Acute CoronAry Syndromes in PatienTs With Undifferentiated cHest Pain

Conditions:   Acute Coronary Syndrome;   Chest Pain
Intervention:   Device: Serial Electrocardiograms
Sponsors:   Wake Forest University Health Sciences;   American Heart Association
Active, not recruiting - verified January 2017

Interleukin-1 (IL-1) Blockade in Acute Myocardial Infarction (VCU-ART3)

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Anakinra 100 mg;   Drug: Anakinra 100 mg;   Drug: Placebo
Sponsors:   Virginia Commonwealth University;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified July 2017

Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Completed - verified July 2017

Effect of RIC on Clinical Outcomes in STEMI Patients Undergoing pPCI

Condition:   Myocardial Reperfusion Injury
Intervention:   Procedure: Remote Ischaemic Conditioning
Sponsors:   Aarhus University Hospital;   Rigshospitalet, Denmark;   Aalborg Universitetshospital;   Odense University Hospital;   Hospital Universitario Central de Asturias;   Clinical Centre of Serbia;   Military Medical Academy, Belgrade, Serbia;   The Hatter Cardiovascular Institute, London W, United Kingdom;   Central Denmark Region;   Region of Southern Denmark;   Prehospital Emergency Medical Service, The North Denmark Region;   Region Zealand;   The Danish Medical Research Council
Recruiting - verified October 2016

Full Length Versus Proximal Renal Arteries Ablation

Condition:   Hypertension, Resistant to Conventional Therapy
Interventions:   Device: Thermocool®Rcatheter;   Device: Thermocool®Rcatheter
Sponsor:   The Second Affiliated Hospital of Chongqing Medical University
Completed - verified July 2017

Clopidogrel Response Evaluation and AnTi-Platelet InterVEntion in High Thrombotic Risk PCI Patients

Condition:   Coronary Heart Disease
Interventions:   Drug: Clopidogrel 75mg;   Drug: Clopidogrel 150mg;   Drug: Aspirin 100mg;   Drug: Cilostazol 100mg
Sponsors:   Chinese Academy of Medical Sciences, Fuwai Hospital;   Beijing Municipal Health Bureau;   Haemonetics Corporation;   Zhejiang Otsuka Pharmaceutical Co., Ltd.
Completed - verified July 2017

Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)

Conditions:   Acute Coronary Syndrome;   Angina Pectoris;   Angina, Unstable;   Myocardial Infarction;   Coronary Artery Disease;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Orsiro;   Device: Synergy;   Device: Resolute Integrity
Sponsor:   Cardio Research Enschede BV
Active, not recruiting - verified July 2017

Clinical Trial of the Edwards Aortic Bioprosthesis, Model 11000

Conditions:   Aortic Valve Disorder;   Aortic Valve Insufficiency;   Aortic Valve Stenosis;   Heart Failure;   Coronary Artery Disease
Intervention:   Procedure: Heart Valve Surgery
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified July 2017

BIOHELIX-I Bare Metal Stent Study

Condition:   Coronary Arteries Disease
Intervention:   Device: PRO-Kinetic Energy Stent
Sponsor:   Biotronik, Inc.
Active, not recruiting - verified July 2017

The Health Access and Recovery Peer Program

Conditions:   Hypertension;   Arthritis;   Coronary Artery Disease;   Hepatitis;   Diabetes;   Asthma;   Hyperlipidemia;   HIV
Intervention:   Behavioral: HARP Intervention
Sponsors:   Emory University;   National Institute of Mental Health (NIMH)
Completed - verified July 2017

Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patients

Condition:   Endstage Kidney Disease
Interventions:   Drug: Vitamin K1;   Drug: Chrystalline Lactose
Sponsors:   Dr. Rachel Holden;   Kingston General Hospital
Recruiting - verified July 2017

Primary Reperfusion Secondary Stenting Trial

Condition:   ST-elevation Myocardial Infarction
Intervention:   Procedure: Stent
Sponsor:   Montreal Heart Institute
Recruiting - verified July 2017

Identification of Carotid Vasa Vasorum and Correlation With Acute Coronary Events

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   University of Pittsburgh;   Lantheus Medical Imaging
Completed - verified July 2017

Clearance Of Mucus In Stents

Conditions:   Lung Neoplasms;   Respiratory Failure;   Pneumonia;   Acute Coronary Syndromes;   Unstable Angina;   Myocardial Infarction;   Cardiac Arrhythmia;   Thromboembolic Disease
Interventions:   Other: Normal Saline;   Other: Sodium Bicarbonate
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified July 2017

Evaluation of Effectiveness and Safety of XIENCE PRIME Stent (IRIS-PRIME)

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea;   Abbott
Active, not recruiting - verified July 2017

Evaluation of Effectiveness and Safety of NOBORI Stent

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea;   Terumo Corporation
Active, not recruiting - verified July 2017

Evaluation of Effectiveness and Safety of PROMUS Element Stent (IRIS-ELEMENT )

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea;   Boston Scientific Corporation
Completed - verified July 2017

Observational Study for Left Main Disease Treatment

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified July 2017

Prevention of Weight Gain in Early Psychoses

Conditions:   Schizophreniform Disorder;   Bipolar I Disorder;   Bipolar II Disorder;   Major Depressive Disorder;   Substance-Induced Psychoses;   Psychosis Not Otherwise Specified;   Schizophrenia;   Schizoaffective Disorder
Interventions:   Behavioral: Behavioural Intervention for the Prevention of Weight Gain;   Other: TAU
Sponsors:   Centre for Addiction and Mental Health;   Canadian Institutes of Health Research (CIHR)
Completed - verified July 2017

Aspirin in Reducing Events in the Elderly

Conditions:   Functional Disability;   Dementia;   Heart Disease;   Stroke;   Cancer;   Bleeding;   Depression
Interventions:   Drug: 100 mg enteric-coated aspirin;   Drug: Placebo
Sponsors:   Minneapolis Medical Research Foundation;   National Health and Medical Research Council, Australia;   Bayer;   Monash University;   Berman Center for Outcomes and Clinical Research;   National Institute on Aging (NIA)
Active, not recruiting - verified July 2017

Coronary Artery Disease Management Using Multislice Computed Tomography and Magnetic Resonance Imaging

Condition:   Coronary Artery Disease
Interventions:   Procedure: CT/MR;   Procedure: Catheterization
Sponsors:   Charite University, Berlin, Germany;   University Hospital Muenster;   Medizinische Hochschule Hannover, Eva Schönenberger, MD;   University of Freiburg
Active, not recruiting - verified July 2017

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

Conditions:   Coronary Artery Disease;   Mitral Valve Regurgitation;   Mitral Valve Incompetence;   Heart Failure
Intervention:   Device: CEP MAGNA MITRAL PERICARDIAL BIOPROSTHESES
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified July 2017

Acarbose Cardiovascular Evaluation Trial

Conditions:   Coronary Heart Disease;   Acute Coronary Syndrome;   Impaired Glucose Tolerance;   Type 2 Diabetes Mellitus (T2DM)
Interventions:   Drug: Acarbose;   Drug: Matching Placebo
Sponsors:   University of Oxford;   Bayer
Completed - verified July 2017

To Assess Safety and Efficacy of Myoblast Implantation Into Myocardium Post Myocardial Infarction

Condition:   Congestive Heart Failure
Interventions:   Biological: MyoCell;   Biological: MyoCell;   Procedure: Hypothermosol
Sponsor:   Bioheart, Inc.
Active, not recruiting - verified July 2017

Genetic Markers of CHD Risk in Men and Women

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Diseases;   Myocardial Infarction;   Inflammation
Intervention:  
Sponsors:   State University of New York at Buffalo;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified July 2008

Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Failure, Congestive;   Heart Diseases
Interventions:   Procedure: CABG surgery plus MED;   Drug: Active Medication Alone;   Procedure: CABG plus MED and SVR
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified July 2017

Nurses' Health Study (Cardiovascular Component)

Conditions:   Cardiovascular Diseases;   Diabetes Mellitus;   Coronary Disease;   Heart Diseases;   Cerebrovascular Accident;   Pulmonary Embolism;   Angina Pectoris;   Myocardial Infarction;   Menopause;   Postmenopause
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified July 2017

Effects of Endotoxin in Normal Human Volunteers

Conditions:   Healthy;   Lung Disease;   Sepsis;   Septic Shock
Interventions:   Drug: Reference Endotoxin;   Drug: Inhaled Nitric Oxide
Sponsor:   National Institutes of Health Clinical Center (CC)
Completed - verified July 7, 2017

Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS)

Conditions:   Cardiovascular Diseases;   Coronary Arteriosclerosis;   Coronary Disease;   Heart Diseases;   Myocardial Infarction;   Myocardial Ischemia
Interventions:   Behavioral: dietary supplements;   Drug: vitamin C;   Drug: vitamin E;   Drug: beta-carotene;   Drug: folic acid/Vitamin B6/Vitamin B12
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified July 2017