Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Evaluation of Cardiac Pathologies on Thoracic CT

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Maastricht University Medical Center;   Bayer
Recruiting - verified September 2016

Coroflex ISAR 2000 Extended Registry (ISAR2000 Extended)

Condition:   Coronary Artery Disease (CAD)
Intervention:   Device: stenting with the Coroflex ISAR sirolimus-eluting stent
Sponsors:   B. Braun Melsungen AG;   Charite University, Berlin, Germany
Recruiting - verified September 2016

Comprehensive Treatment of Angina in Women With Microvascular Dysfunction

Conditions:   Angina Pectoris;   Coronary Microvascular Disease
Interventions:   Dietary Supplement: Diet;   Behavioral: Training;   Drug: Medication (with statin and ACE-inhibition)
Sponsors:   Bispebjerg Hospital;   University Hospital Bispebjerg and Frederiksberg;   Cambridge Weight Plan Limited
Not yet recruiting - verified September 2016

Hemostatic Compression Patterns After Transradial Coronary Intervention

Condition:   Coronary Disease
Interventions:   Device: experimental group;   Device: control group
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Not yet recruiting - verified August 2016

Predicting Fluid Responsiveness in on Pump Coronary Artery Bypass Graft Using Extra Systoles

Conditions:   Hypovolemia;   Coronary Artery Disease;   Fluid Overload
Intervention:   Procedure: Fluids
Sponsors:   University of Aarhus;   Aarhus University Hospital
Recruiting - verified September 2016

Frailty as an INstrument for Evaluation of Elderly Patients With Non ST ElevationMyocardial Infarction (NSTEMI) - 5 Year Follow up

Conditions:   Non ST Elevation Myocardial Infarction (NSTEMI);   Frailty
Intervention:   Other: This is an observational study
Sponsor:   Linkoeping University
Not yet recruiting - verified September 2016

Cardio‑Safety of Dihydroartemisinin‑Piperaquine and Pharmacokinetics of Piperaquine Amongst Pregnant Women in Tanzania

Conditions:   Malaria;   Pregnancy;   Cardiotoxicity;   Parasitemia
Interventions:   Drug: sulfadoxine-pyrimethamine (SP);   Drug: dihydroartemisinin-piperaquine (DHA-PQP)
Sponsors:   London School of Hygiene and Tropical Medicine;   Kilimanjaro Christian Medical Centre, Tanzania;   National Institute for Medical Research, Tanzania
Recruiting - verified June 2016

Women's Heart Attack Research Program- Imaging Study

Condition:   Myocardial Infarction
Interventions:   Device: OCT;   Other: CMR
Sponsor:   New York University School of Medicine
Recruiting - verified September 2016

Effects of Morphine on Loading-dose Ticagrelor in Patients With ST-segment Elevation Myocardial Infarction

Condition:   ST-segment Elevation Myocardial Infarction
Interventions:   Drug: Morphine;   Drug: metoclopramide;   Drug: saline
Sponsor:   General Hospital of Chinese Armed Police Forces
Recruiting - verified September 2016

Bivalirudin in Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Bivalirudin;   Drug: heparin
Sponsor:   Shenzhen Salubris Pharmaceuticals Co., Ltd.
Not yet recruiting - verified September 2016

Real Time Myocardial Perfusion Echocardiography for Coronary Allograft Vasculopathy

Condition:   Cardiac Allograft Vasculopathy
Interventions:   Drug: Perflutren Lipid Microsphere;   Procedure: RTMPE
Sponsors:   Mayo Clinic;   University of Calgary
Recruiting - verified September 2016

The Syndrome X-ercise Study SYNDEX

Condition:   Angina
Intervention:   Other: Exercise training
Sponsors:   Helse Stavanger HF;   University of Bergen;   University of Stavanger
Recruiting - verified September 2016

Acute Coronary Syndrome Sri Lanka Audit Project

Conditions:   Acute Coronary Syndrome;   Unstable Angina;   Non ST Elevation Myocardial Infarction;   ST Elevation Myocardial Infarction
Intervention:   Drug: aspirin, clopidogrel, statin, enoxaparin, streptokinase
Sponsors:   University of Colombo;   Ministry of Health, Sri Lanka
Withdrawn - verified September 2016

The Effect of Dan-shen Extract On Lipoprotein Associated PHospholipase A2 Levels IN Patients With Stable Angina Pectoris

Conditions:   Angina, Stable;   Inflammation
Interventions:   Drug: Dan-shen extract;   Drug: Placebo;   Other: Standard medical care
Sponsors:   Taizhou Fourth People's Hospital;   Shanghai 10th People's Hospital
Recruiting - verified September 2016

Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study

Condition:   ST-segment Elevation Myocardial Infarction
Interventions:   Drug: alteplase;   Drug: Placebo
Sponsor:   Vastra Gotaland Region
Recruiting - verified June 2016

A Prospective, Single-arm, Multi-centre, Observational, Real World Registry

Condition:   Angina Pectoris
Intervention:   Device: Sirolimus Eluting Coronary Stent System
Sponsor:   Meril Life Sciences Pvt. Ltd.
Not yet recruiting - verified September 2016

Efficacy of Furosemide Versus Vascular Filling in Patients With Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction With Right Ventricular Extension
Interventions:   Drug: Furosemide;   Drug: Placebo filling;   Drug: Placebo furosemide;   Drug: Vascular filling
Sponsor:   Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified July 2016

7 Year Follow-up Study of the DanRisk Population

Conditions:   Cardiovascular Disease;   Coronary Artery Calcification;   Atherosclerosis
Intervention:  
Sponsor:   Odense University Hospital
Completed - verified July 2016

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment - at the Time of Coronary Angiography - Affect Management Strategy, Hospital Costs and Outcomes?

Conditions:   Chest Pain;   Stable Angina;   Acute Coronary Syndrome;   Non ST Segment Elevation Acute Coronary Syndrome
Intervention:   Device: Routine Measurement of FFR
Sponsors:   University Hospital Southampton NHS Foundation Trust.;   Liverpool Heart and Chest Hospital NHS Foundation Trust
Not yet recruiting - verified September 2016

Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention

Conditions:   Radial Artery Spasm;   Angina;   Coronary Artery Disease
Interventions:   Drug: Topical Nitroglycerine;   Drug: Topical Lidocaine
Sponsor:   Aultman Health Foundation
Not yet recruiting - verified September 2016

Effects of Beta-blockade on Platelet Aggregation in Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Carvedilol;   Drug: Metoprolol
Sponsor:   Federico II University
Recruiting - verified June 2016

Intra-patient Study With Polymer Free Drug Eluting Stent Versus Abluminal Biodegradable Polymer Drug Eluting Stent With Early OCT (Optical Coherence Tomography) Follow up

Condition:   Coronary Artery Disease
Interventions:   Device: Coroflex® ISAR Drug-eluting stent;   Device: Ultimaster® Drug-eluting stent
Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   B.Braun Surgical SA
Recruiting - verified July 2016

The Wire-free Invasive Functional Imaging (WIFI) Study

Condition:   Coronary Artery Disease
Intervention:   Other: QFR (observational)
Sponsor:   Niels Ramsing Holm
Recruiting - verified September 2016

STrategic Reperfusion in Elderly Patients Early After Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Drug: Tenecteplase;   Drug: Clopidogrel;   Procedure: Coronary angiography;   Procedure: Primary PCI
Sponsors:   Katholieke Universiteit Leuven;   Boehringer Ingelheim;   Life Sciences Research Partners;   Fund for Clinical Cardiovascular Research at LRD
Not yet recruiting - verified September 2016

Bioresorbable Vascular Scaffolds Versus Stents in Patients With Chronic Total Occlusion

Condition:   Coronary Artery Disease
Interventions:   Device: Everolimus-eluting bioresorbable vascular scaffold;   Device: Everolimus-eluting stent
Sponsor:   University of Luebeck
Recruiting - verified September 2016

CT COMPARE: CT COronary Angiography to Measure PlAque REduction

Condition:   Cardiovascular Disease
Interventions:   Drug: Rosuvastatin;   Drug: Atorvastatin
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified September 2016

The Impact of Opioids in Coronary Heart Disease

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   Ruhr University of Bochum;   Mundipharma Research GmbH & Co KG
Completed - verified September 2016

A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL_112;   Other: Placebo
Sponsor:   CSL Behring
Recruiting - verified September 2016

Drug Eluting Balloon for Treatment of Unstable Angina

Condition:   Angina, Unstable
Interventions:   Device: drug eluting balloon; cutting balloon;   Device: drug eluting stent
Sponsor:   Yun Dai Chen
Recruiting - verified September 2016

The Effect of Resistance Training on Proprotein Subtilisin Convertase Kexin 9 Level After Coronary Bypass Surgery

Condition:   Coronary Artery Disease
Interventions:   Behavioral: resistance training;   Behavioral: aerobic training
Sponsor:   National Cardiovascular Center Harapan Kita Hospital Indonesia
Active, not recruiting - verified September 2016

MYocardial DAmage AND MIcrobiota STUDY

Conditions:   Chronic Stable Angina;   Periprocedural Myocardial Damage
Interventions:   Dietary Supplement: Probiotic;   Other: Placebo
Sponsors:   San Filippo Neri General Hospital;   MENDES S.A., Lugano, Switzerland;   University of Roma La Sapienza
Not yet recruiting - verified September 2016

Effect of Sitagliptin on Progression of Coronary Intermediate Lesion

Conditions:   Atherosclerosis;   Type 2 Diabetes Mellitus
Interventions:   Drug: Sitagliptin;   Drug: Placebo
Sponsor:   Li Bo
Recruiting - verified September 2016

Effects of Personalized Training Program on Coronary Flow Reserve in Healthy Volunteers

Conditions:   Coronary Artery Disease;   Heart Infarction
Interventions:   Behavioral: physical exercise;   Behavioral: limited physical exercise
Sponsor:   Göteborg University
Active, not recruiting - verified September 2016

coRonary assEssment of Preoperative vaLvulopathy pAtients Using ComputEd Tomographic Angiography (REPLACE)

Conditions:   Heart Valve Diseases;   Coronary Artery Disease
Intervention:   Other: Computed tomographic angiography
Sponsors:   Chinese Academy of Medical Sciences, Fuwai Hospital;   Guangdong General Hospital;   West China Hospital;   Fourth Military Medical University;   Wuhan Union Hospital, China
Recruiting - verified September 2016

Coroflex ISAR 2000 Registry

Condition:   Coronary Artery Disease (CAD)
Intervention:   Device: stenting with the Coroflex ISAR sirolimus-eluting stent
Sponsors:   B. Braun Melsungen AG;   Charite University, Berlin, Germany
Active, not recruiting - verified September 2016

BIOFREEDOM Stent Versus ORSIRO Stent: SORT OUT IX

Condition:   Ischaemic Heart Disease
Interventions:   Device: Biofreedom;   Device: Orsiro
Sponsors:   Odense University Hospital;   Aarhus University Hospital Skejby;   Aalborg Universitetshospital;   Rigshospitalet, Denmark
Recruiting - verified September 2016

Bright Light Therapy Efficacy for Depressive Symptoms Following Cardiac Surgery or Acute Coronary Syndrome: Pilot Trial

Condition:   Depressive Symptoms Post Cardiac Surgery or Post Acute Coronary Syndrome
Interventions:   Device: Bright Light Therapy Lamp;   Device: Modified Dim Lamp
Sponsor:   McGill University
Recruiting - verified September 2016

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified September 2016

Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial

Conditions:   Stable Angina;   Unstable Angina;   Non-ST Segment Elevation Myocardial Infarction
Interventions:   Device: CX-ISAR;   Device: Orsiro;   Drug: 3-months DAPT;   Drug: 1-year DAPT
Sponsors:   Seoul National University Hospital;   B. Braun Korea Co., Ltd.
Recruiting - verified September 2016

A Comparison of an Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent for Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome
Interventions:   Device: Orsiro;   Device: Xience
Sponsors:   University Hospital Inselspital, Berne;   University of Lausanne Hospitals
Recruiting - verified September 2016

Edoxaban in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With Aspirin and Clopidogrel

Condition:   Coronary Artery Disease
Interventions:   Drug: Edoxaban 60 mg;   Drug: Edoxaban 30 mg;   Drug: Clopidogrel 75 mg;   Drug: Aspirin 81 mg
Sponsors:   University of Florida;   Daiichi Sankyo Inc.
Recruiting - verified September 2016

Atorvastatin Effectiveness and Safety in Cardiology Patients in Real World Setting

Condition:   Coronary Artery Disease, Hypercholesterolemia, Hypertension
Intervention:   Other: No intervention
Sponsor:   Pfizer
Not yet recruiting - verified September 2016

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

Conditions:   Secondary Prevention;   Stroke;   Ischemic Heart Disease;   Coronary Heart Disease
Interventions:   Drug: Acetylsalicylic Acid (Asprin, BAYE4465);   Drug: Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
Sponsor:   Bayer
Recruiting - verified September 2016

Vorapaxar as an Add-On Antiplatelet Therapy in Post Myocardial Infarction Patients With and Without Diabetes Mellitus

Conditions:   Myocardial Infarction;   Diabetes Mellitus
Interventions:   Drug: Vorapaxar;   Drug: Clopidogrel;   Drug: Aspirin
Sponsors:   University of Florida;   Merck Sharp & Dohme Corp.
Recruiting - verified September 2016

Effects of Inspiratory Muscles Strengthening Among Coronary Patients on the Sleep Apnea Obstructive Syndrome

Conditions:   Sleep Apnea, Obstructive;   Acute Coronary Syndrome
Interventions:   Device: POWERbreathe Fitness Plus, (POWERbreathe International Ltd, UK) [Inspiratory muscles strengthening];   Other: Control
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting - verified September 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified September 2016

Examining How Acute Treatment Contributes to Variations in AMI Mortality Across the English NHS

Condition:   Myocardial Infarction
Intervention:   Other: Standard Hospital Care
Sponsor:   London School of Economics and Political Science
Active, not recruiting - verified September 2016

Bivalirudin vs Heparin in NSTEMI and STEMI in Patients on Modern Antiplatelet Therapy in SWEDEHEART

Conditions:   ST-segment Elevation Myocardial Infarction;   Non ST-segment Elevation Myocardial Infarction
Interventions:   Drug: bivalirudin;   Drug: Heparin
Sponsors:   Uppsala University;   Lund University
Active, not recruiting - verified September 2016

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Active, not recruiting - verified September 2016

A Study to Evaluate the Use of SOMVC001 (GALA) Vascular Conduit Preservation Solution in Patients Undergoing CABG (STEPS)

Condition:   Coronary Artery Disease
Interventions:   Device: SOMVC001 Vascular Conduit Solution;   Other: Standard of care Heparin-dosed saline
Sponsors:   Perrault Louis P.;   Montreal Heart Institute;   Somahlution LLC
Recruiting - verified September 2016

Improvement of Subjective Well-Being by Ranolazine Among Unrevascularized Chronic Stable Coronary Artery Disease Patients

Condition:   Angina
Interventions:   Drug: Ranolazine;   Drug: Sugar pill
Sponsors:   North Florida Foundation for Research and Education;   Gilead Sciences
Completed - verified September 2016

Cadmium-zinc-telluride (CZT) Imaging of Myocardial Blood Flow (MBF) (SPECT MBF)

Condition:   Coronary Heart Disease
Intervention:   Other: single photon emission computed tomography
Sponsors:   Ottawa Heart Institute Research Corporation;   GE Healthcare
Recruiting - verified September 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified September 2016

Real Life Long-term Adherence to Ticagrelor After PCI for Acute Coronary Syndromes

Condition:   Acute Coronary Syndrome (ACS)
Intervention:   Drug: Ticagrelor
Sponsor:   IHF GmbH - Institut für Herzinfarktforschung
Recruiting - verified September 2016

Study of a Quality Improvement Toolkit in Kerala, India, Among Hospitals Treating Acute Coronary Syndrome Patients

Condition:   Acute Coronary Syndrome
Intervention:   Behavioral: Quality Improvement Toolkit
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified September 2016

The OCT SORT-OUT VIII Study

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Myocardial Infarction
Interventions:   Device: Everolimus eluting bioresorbable polymer stent;   Device: Biolimus eluting bioresorbable polymer stent
Sponsors:   Aarhus University Hospital Skejby;   Biosensors International;   Boston Scientific Corporation
Active, not recruiting - verified September 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified September 2016

Reversing Ticagrelor's Effects With Fresh Platelets

Condition:   Coronary Artery Disease
Interventions:   Drug: Loading dose;   Drug: Loading dose;   Drug: Maintenance dose;   Drug: Maintenance dose
Sponsors:   Icahn School of Medicine at Mount Sinai;   AstraZeneca
Completed - verified September 2016

Ventricular Remodeling and Heart Failure After Myocardial Infarction: A Community Study

Conditions:   Heart Failure;   Myocardial Infarction
Intervention:  
Sponsor:   Mayo Clinic
Recruiting - verified September 2016

IdeNtifying High riSk Patients Post Myocardial Infarction With REduced Left Ventricular Function Using External Loop Recorders (INSPIRE-ELR Study)

Condition:   Post Myocardial Infarction Patients With Ejection Fraction Less Than or Equal to 35%
Intervention:   Device: External Loop Recorder
Sponsors:   Medtronic BRC;   Medtronic
Active, not recruiting - verified September 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified September 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified September 2016

Application for Self-Monitoring of Cardiovascular Risk

Condition:   Coronary Disease
Intervention:   Device: Self Monitoring Software Application
Sponsor:   Mayo Clinic
Completed - verified September 2016

Long-Term rIsk, Clinical manaGement and Healthcare Resource Utilization of Stable CAD in Post MI Patients

Condition:   Stable Coronary Artery Disease (CAD), Myocardial Infarction
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified September 2016

Detecting and Addressing Preclinical Disability

Conditions:   Back Pain;   Coronary Artery Disease;   Chronic Obstructive Pulmonary Disease;   Diabetes;   Hypertension;   Multiple Sclerosis;   Osteoporosis;   Osteoarthritis;   Rheumatoid Arthritis;   Stroke
Intervention:   Other: Tailored advice from a physiotherapist and/or an occupational therapist through the myOSCAR patient portal
Sponsors:   McMaster University;   Labarge Optimal Aging Initiative (Private Donor)
Active, not recruiting - verified September 2016

Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia

Conditions:   Coronary Artery Disease;   Angina, Stable;   Exercise Test;   Biological Markers;   SPECT
Intervention:  
Sponsor:   University Hospital, Basel, Switzerland
Recruiting - verified September 2016

Sirolimus Eluting ORSIRO Stent Versus Biolimus-eluting NOBORI Stent

Conditions:   Coronary Artery Disease;   Ischemic Heart Disease
Intervention:   Device: Drug-eluting stent
Sponsor:   Odense University Hospital
Active, not recruiting - verified September 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified September 2016

Cooling in Myocardial Infarction

Condition:   ST-elevation Myocardial Infarction
Intervention:   Device: EMCOOLS flex pad; Philips Innercool RTx
Sponsors:   Medical University of Vienna;   Austrian Science Fund (FWF)
Active, not recruiting - verified September 2016

Safety Study of Allogeneic Mesenchymal Precursor Cell Infusion in MyoCardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Other: 12.5 M Mesenchymal Precursor Cells (MPC);   Other: Placebo;   Other: 25M Mesenchymal Precursor Cells (MPC)
Sponsors:   Mesoblast, Ltd.;   Teva Pharmaceuticals USA
Active, not recruiting - verified September 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: Placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified September 2016

Antiplatelet Therapy Guided by Thrombelastography in Patients With Acute Coronary Syndromes (TEGCOR Study)

Conditions:   Thrombosis;   Coronary Artery Disease
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel
Sponsor:   Indiana University
Terminated - verified September 2016

Reducing Radioisotope Dose: the Half-Dose CZT Study

Condition:   Coronary Artery Disease
Intervention:   Other: Half-dose isotope for NuclearStressTest
Sponsors:   S.M.Chang, MD;   Houston Methodist Research Institute
Recruiting - verified September 2016

The Nordic-Baltic Bifurcation Study IV

Condition:   Coronary Artery Disease
Interventions:   Procedure: Implantation of coronary stent in bifurcation lesion;   Procedure: Implantation of coronary stent in bifurcation lesion
Sponsors:   Niels Ramsing Holm;   Johnson & Johnson
Active, not recruiting - verified September 2016

TAKO-TSUBO Cardiomyopathy and Genetic

Conditions:   Tako-TSUBO Cardiomyopathy;   Acute Coronary Syndrome
Intervention:  
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Fédération Française de Cardiologie
Completed - verified February 2016

Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration

Condition:   Myocardial Infarction
Intervention:   Biological: CAP-1002 Allogeneic Cardiosphere-Derived Cells
Sponsors:   Capricor Inc.;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI);   California Institute for Regenerative Medicine (CIRM)
Recruiting - verified September 2016

Study to Develop a Non-invasive Marker for Monitoring Myocardial Fibrosis

Conditions:   Hypertrophic Cardiomyopathy;   Acute Coronary Syndrome
Intervention:   Radiation: 99mTc-NC100692
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting - verified September 2016

Systolic Blood Pressure Intervention Trial

Condition:   Hypertension
Interventions:   Other: Intensive control of SBP;   Other: Standard BP arm
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Institute on Aging (NIA);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Institute of Neurological Disorders and Stroke (NINDS);   Wake Forest Baptist Health
Active, not recruiting - verified September 2016

Morphine In Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: morphine chlorhydrate;   Drug: saline solution
Sponsors:   French Cardiology Society;   Institut National de la Santé Et de la Recherche Médicale, France
Active, not recruiting - verified June 2016

Carpentier-Edwards PERIMOUNT Magna Ease Pericardial Bioprosthesis, Model 3300TFX

Conditions:   Coronary Artery Disease;   Aortic Valve Disorder;   Heart Failure;   Aortic Valve Stenosis;   Aortic Valve Insufficiency
Intervention:   Device: Implantation of CEP Magna Ease Model 3300TFX
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified September 2016

Long-term Evaluation of Patients Receiving Bone Marrow-derived Cell Administration for Heart Disease

Conditions:   Acute Myocardial Infarction;   Ischemic Cardiomyopathy;   Dilated Cardiomyopathy;   Heart Failure
Intervention:   Biological: autologous bone marrow-derived cells
Sponsor:   Johann Wolfgang Goethe University Hospital
Active, not recruiting - verified September 2016

Intramyocardial Transplantation of Bone Marrow Stem Cells in Addition to Coronary Artery Bypass Graft (CABG) Surgery

Conditions:   Myocardial Ischemia;   Coronary Artery Disease
Interventions:   Drug: CD133+ autologous bone marrow stem cell;   Drug: Placebo
Sponsors:   Miltenyi Biotec GmbH;   German Federal Ministry of Education and Research
Terminated - verified September 2016

Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE)

Conditions:   Acute Coronary Syndrome;   Chest Pain
Intervention:  
Sponsor:   Kavitha Chinnaiyan
Completed - verified September 2016

The Nordic Bifurcation Study III

Condition:   Coronary Artery Disease
Intervention:   Procedure: Percutaneous coronary intervention (PCI)
Sponsors:   Niels Ramsing Holm;   Johnson & Johnson
Active, not recruiting - verified September 2016

Prochymal® (Human Adult Stem Cells) Intravenous Infusion Following Acute Myocardial Infarction (AMI)

Condition:   Myocardial Infarction
Interventions:   Drug: Prochymal®;   Drug: Placebo
Sponsor:   Mesoblast International Sàrl
Completed - verified September 2016

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

Conditions:   Coronary Artery Disease;   Mitral Valve Regurgitation;   Mitral Valve Incompetence;   Heart Failure
Intervention:   Device: CEP MAGNA MITRAL PERICARDIAL BIOPROSTHESES
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified September 2016

Study of Women With Acute Coronary Syndromes and Nonobstructive Coronary Artery Disease

Condition:   Acute Coronary Syndromes
Interventions:   Procedure: Intravascular ultrasound;   Procedure: MRI
Sponsors:   New York University School of Medicine;   Doris Duke Charitable Foundation
Active, not recruiting - verified September 2016

An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine)

Conditions:   Coronary Artery Bypass Surgery;   Coronary Heart Disease;   Coronary Artery Bypass Grafting;   Cardiopulmonary Bypass;   Ischemic Heart Disease;   Heart Failure, Congestive
Intervention:   Drug: Nesiritide
Sponsor:   Scios, Inc.
Withdrawn - verified July 2011

Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study

Conditions:   Myocardial Infarction;   Angina, Unstable
Intervention:  
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation
Recruiting - verified September 2016

HEROIC (Heparin Requirement in Counterpulsation)

Condition:   Cardiogenic Shock
Interventions:   Drug: Heparin;   Other: Without Heparin
Sponsor:   Justin Trivax
Completed - verified September 2016

Paleolithic Diet in the Treatment of Glucose Intolerance

Conditions:   Hyperglycemia;   Coronary Heart Disease
Intervention:   Behavioral: Paleolithic diet vs Mediterranean diet
Sponsor:   Lund University Hospital
Completed - verified September 2016

Michelangelo - Oasis 5

Condition:   Thromboembolism
Interventions:   Drug: Fondaparinux;   Drug: enoxaparin
Sponsors:   GlaxoSmithKline;   University of Chicago;   Organon;   Sanofi;   Duke University
Completed - verified September 2016

OASIS-6 : The Safety and Efficacy of Fondaparinux Versus Control Therapy in Patients With ST Segment Elevation Acute Myocardial Infarction

Condition:   Thromboembolism
Interventions:   Drug: fondaparinux - UFH not indicated;   Other: Control - UFH not indicated;   Drug: Fondaparinux - UFH indicated;   Drug: Control - UFH
Sponsors:   GlaxoSmithKline;   Sanofi
Completed - verified September 2016

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified September 2016