Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Endothelial Function Guided Therapy in Patients With Non-obstructive Coronary Artery Disease

Condition:   Non-obstructive Coronary Artery Disease
Intervention:   Other: Endothelial function guided therapy
Sponsors:   Peking University;   Mayo Clinic;   Peking University Shougang Hospital
Recruiting

Study of MeRes100 in the Treatment of Patient With Coronary Artery Disease.

Condition:   Coronary Artery Disease
Interventions:   Device: MeRes100 Sirolimus-Eluting BioResorbable Vascular Scaffold System;   Device: Xience EES Everolimus Eluting Coronary Stent System
Sponsor:   Meril Life Sciences Pvt. Ltd.
Not yet recruiting

Evaluation of the CAD-det System, a Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Cardiovascular Disease
Intervention:  
Sponsors:   AusculSciences Canada Inc.;   Ottawa Heart Institute Research Corporation;   Horizon Health Network;   Scarborough Rouge Hospital;   University of Calgary
Recruiting

Coronary Artery Disease Management Using Multislice Computed Tomography and Magnetic Resonance Imaging

Condition:   Coronary Artery Disease
Interventions:   Procedure: CT/MR;   Procedure: Catheterization
Sponsors:   Charite University, Berlin, Germany;   University Hospital Muenster;   Charite University, Berlin, Eva Schönenberger, MD;   University of Freiburg
Completed

MCRcI® Stem Cell Treatment for Diffuse Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Biological: MCRcI® stem cells
Sponsors:   Honya Medical Inc;   Chang Gung Memorial Hospital
Recruiting

Data Acquisition for Optimization of Coronary Artery Disease (CAD) Algorithm

Condition:   Coronary Artery Disease
Intervention:   Device: CADScor1
Sponsor:   Acarix
Completed

Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Procedure: Computed tomography angiography (cardiac CT);   Procedure: Invasive coronary angiography (ICA)
Sponsor:   Charite University, Berlin, Germany
Recruiting

AZD5718 Phase IIa Study to Evaluate Efficacy, Safety and Tolerability of Oral AZD5718 in Patients With Coronary Artery Disease (CAD).

Condition:   Coronary Artery Disease
Interventions:   Drug: AZD5718;   Drug: Placebo
Sponsor:   AstraZeneca
Recruiting

Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease 2

Conditions:   Angina Pectoris;   Atherosclerosis;   Coronary Artery Disease;   Myocardial Ischemia
Intervention:   Diagnostic Test: Diagnostic tests
Sponsor:   University of Aarhus
Recruiting

Impact of Chronic Kidney Disease on the Effects of Ticagrelor in Patients With Diabetes and Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Diabetes Mellitus
Intervention:   Drug: ticagrelor
Sponsor:   University of Florida
Recruiting

Program Using a Mobile Application Versus Telephone Advice on Patients at Risk of Coronary Heart Disease : a Pilot RCT

Condition:   Coronary Heart Disease
Intervention:   Device: App support Programme (ASP) group
Sponsors:   The Hong Kong Polytechnic University;   Tuen Mun Hospital
Recruiting

PIONEER III Trial to Assess Safety and Efficacy of the BuMA Supreme™ Drug Coated Coronary Stent in Patients With Coronary Disease

Condition:   Coronary Artery Disease
Interventions:   Device: BuMA Supreme DES;   Device: Xience or Promus DES
Sponsors:   Sino Medical Sciences Technology Inc.;   Nova Vascular LLC
Active, not recruiting

Relationship of Oral Status to Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Periodontal Diseases
Intervention:   Other: radiographic evaluations were done
Sponsors:   Baskent University;   Ankara University
Completed

Quantitative Flow Ratio (QFR) Guided Revascularization Strategy for Patients Undergoing Primary Valve Surgery With Comorbid Coronary Artery Disease

Conditions:   Primary Valvular Heart Disease With Comorbid Coronary Artery Disease;   Planned to Undergo Elective On-pump Valve Surgery Due to Primary Mitral and/or Aortic Valvular Heart Disease
Interventions:   Device: QFR-guided strategy;   Other: CAG-guided strategy
Sponsors:   Ruijin Hospital;   Med-X Research Institute, Shanghai Jiao Tong University
Recruiting

Coronary Artery Disease (CAD) in Suppressed HIV-infected

Condition:   Virus-HIV
Intervention:   Biological: blood test
Sponsors:   University Hospital, Montpellier;   Hospital Universitario La Paz;   Hospital Reina Sofia, Murcia;   Hospital Vall D’ Hebron Barcelon;   Patras University Hospital, Patras
Terminated

Empagliflozin Versus Sitagliptin Therapy for Improvement of Myocardial Perfusion Reserve in Diabetic Patients With Coronary Artery Disease

Conditions:   Diabetes Mellitus;   Coronary Disease
Interventions:   Drug: Empagliflozin;   Drug: Sitagliptin
Sponsor:   CHEOL WHAN LEE, M.D., Ph.D
Completed

The Heartflow Coronary Disease Progression Evaluation Study

Condition:   Coronary Artery Disease
Intervention:   Diagnostic Test: Coronary computed tomography angiography
Sponsor:   Erasmus Medical Center
Recruiting

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes?

Conditions:   Chest Pain;   Stable Angina;   Acute Coronary Syndrome;   Non ST Segment Elevation Acute Coronary Syndrome
Intervention:   Device: Routine Measurement of FFR
Sponsors:   University Hospital Southampton NHS Foundation Trust;   Liverpool Heart and Chest Hospital NHS Foundation Trust
Active, not recruiting

Improved Prediction of Functional Recovery After Revascularisation Using Combined Assessment of Myocardial Ischaemia and Viability by CMR - Pilot Study

Conditions:   Cardiovascular Diseases;   Ischemic Cardiomyopathy;   Cardiac Ischemia
Interventions:   Device: Research CMR scan;   Device: Research 3D transthoracic echocardiogram;   Other: 6-minute walk test
Sponsor:   King's College London
Recruiting

Rehabilitation at Home Using Mobile Health In Older Adults After Hospitalization for Ischemic Heart Disease

Condition:   Ischemic Heart Disease
Interventions:   Other: mHealth-CR;   Other: Usual Care
Sponsors:   NYU Langone Health;   National Institutes of Health (NIH)
Not yet recruiting

Use of Magnetocardiography in Evaluation of Patients Going for Cardiac Catheterization

Conditions:   Acute Coronary Syndrome;   Coronary Artery Stenosis;   Myocardial Ischemia
Intervention:   Diagnostic Test: CardioFlux Magnetocardiograph
Sponsor:   Genetesis Inc.
Recruiting

Prospective International Study of Coronary Subtraction Using 320 Detector Row CT (CorSub)

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

BeSingCardioRehab: CR in Belgium Versus Singapore

Condition:   Ischemic Heart Disease
Intervention:   Other: Cardiac Rehabilitation
Sponsors:   Hasselt University;   Jessa Hospital
Recruiting

Prevention of Coronary Heart Disease in Morbidly Obese Patients

Conditions:   Morbid Obesity;   Hypertension;   Type 2 DM;   Obstructive Sleep Apnea;   Osteoarthrosis
Interventions:   Procedure: Bariatric Surgery;   Behavioral: Conservative Treatment:
Sponsors:   The Hospital of Vestfold;   Oslo University Hospital
Active, not recruiting

Bioresorbable Polymer-Coated EES in Patients at High Bleeding Risk Undergoing PCI Followed by 1-Month DAPT

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome
Interventions:   Drug: Aspirin;   Drug: P2Y12 inhibitor
Sponsor:   Humanitas Hospital, Italy
Recruiting

Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   HeartFlow, Inc.
Completed

ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arrest

Conditions:   Cardiac Arrest Due to Underlying Cardiac Condition;   Ventricular Fibrillation;   Cardiopulmonary Arrest With Successful Resuscitation
Interventions:   Procedure: Initial CCL admission;   Diagnostic Test: Initial ICU admission
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Active, not recruiting

Clinical Study Comparing Single Long BioMimeTM Morph Coronary Stent System vs. Two Overlapping Xience Family Coronary Stent Systems in the Treatment of Patients With Long de Novo Lesions.

Condition:   Coronary Artery Disease
Interventions:   Device: BioMime™ Morph - Sirolimus Eluting Coronary Stent System;   Device: Xience family Everolimus Coronary Stent Systems
Sponsor:   Meril Life Sciences Pvt. Ltd.
Not yet recruiting

Coronary Angiography in Critically Ill Patients With Type II Myocardial Infarction

Conditions:   Type 2 Myocardial Infarction;   Coronary Artery Disease;   Percutaneous Coronary Intervention;   Critical Illness
Intervention:   Procedure: percutaneous coronary intervention (stenting)
Sponsor:   University Medical Centre Ljubljana
Not yet recruiting

Tai Chi Exercises on Physical Activity and Pulmonary Function in CABG

Condition:   Coronary Artery Disease
Interventions:   Other: Aerobic Exercises;   Other: Tai Chi Exercises
Sponsor:   Riphah International University
Completed

The "Know Your Numbers" Program in Atahualpa

Conditions:   Cardiovascular Risk Factors;   Stroke;   Ischemic Heart Disease
Intervention:   Other: Lifestyle counseling
Sponsors:   Hospital Clínica Kennedy;   Universidad de Especialidades del Espíritu Santo
Completed

CCTA to Optimize the Diagnostic Yield of Invasive Angiography

Condition:   Coronary Artery Disease
Intervention:   Diagnostic Test: Coronary Computed Tomographic Angiography
Sponsors:   Hamilton Health Sciences Corporation;   Hamilton Academic Health Sciences Organization
Recruiting

Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial)

Conditions:   Coronary Artery Disease;   Aortic Valve Stenosis;   Mitral Valve Insufficiency
Interventions:   Behavioral: PACO intervention for CABG patients;   Behavioral: PACO intervention for AVR patients;   Behavioral: PACO intervention for MVR patients
Sponsors:   Kuopio University Hospital;   UKK Institute;   Turku University Hospital
Recruiting

Quantitative Coronary Angiography Versus Intravascular Ultrasound GUIDancE for Drug-Eluting Stent Implantation

Conditions:   Coronary Disease;   Coronary Stenoses
Interventions:   Device: quantitative coronary angiography guided coronary intervention with sirolimus-eluting Orsiro stent;   Device: intravascular ultrasound guided coronary intervention with sirolimus-eluting Orsiro stent
Sponsors:   CHEOL WHAN LEE, M.D., Ph.D;   Biotronik SE & Co. KG
Recruiting

Safety and Effectiveness of Agent Paclitaxel-Coated PTCA Balloon Catheter. (AGENT Japan SV)

Condition:   Coronary Artery Disease
Interventions:   Device: Device: Paclitaxel-Coated PTCA Balloon Catheter;   Device: SeQuent Please Drug Eluting Balloon Catheter with Paclitaxel
Sponsor:   Boston Scientific Corporation
Not yet recruiting

Elixir Medical Evaluation of the DESolve® Novolimus Eluting Bioresorbable Coronary Scaffold System - Cx Registry

Condition:   Coronary Artery Disease
Intervention:   Device: DESolve Cx drug eluting coronary scaffold system
Sponsor:   Elixir Medical Corporation
Active, not recruiting

Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

Condition:   Sickle Cell Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Cardiac and Endothelial Function Response to Early Exercise Training After Coronary Artery Bypass Surgery

Conditions:   Coronary Artery Bypass Grafting;   Coronary Artery Disease;   Cardiac Rehabilitation
Interventions:   Other: Ventilatory Muscle Training (TREMVEN);   Other: Aerobic Training (AERO);   Other: Isometric Handgrip Training (ISO)
Sponsor:   Instituto de Cardiologia do Rio Grande do Sul
Completed

Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation

Condition:   Coronary Artery Disease
Interventions:   Device: iFR;   Device: FFR
Sponsor:   Imperial College London
Active, not recruiting

FFR vs. icECG in Coronary Bifurcations

Condition:   Coronary Artery Disease
Intervention:   Procedure: Intracoronary ECG
Sponsor:   University National Heart Hospital
Completed

Telemedicine in Cardiac Surgery: A Pilot Study

Condition:   Coronary Artery Disease
Intervention:   Other: Evaluate video clinic visit prior to Face-to-Face usual care visit
Sponsor:   VA Office of Research and Development
Completed

Alternative in Beta Blocker Intolerance: The ABBI Trial

Condition:   Coronary Artery Disease
Intervention:   Drug: Nebivolol
Sponsors:   Minneapolis Heart Institute Foundation;   Forest Laboratories
Terminated

EXCEL Clinical Trial

Conditions:   Chronic Coronary Occlusion;   Unprotected Left Main Coronary Artery Disease;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Interventions:   Device: Percutaneous Coronary Intervention;   Procedure: CABG
Sponsor:   Abbott Medical Devices
Completed

ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

Conditions:   Healthy Volunteers;   Atherosclerotic Heart Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting

A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes

Conditions:   Diabetic Nephropathies;   Coronary Artery Disease
Interventions:   Drug: Allopurinol;   Drug: Placebo
Sponsors:   Alessandro Doria;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Juvenile Diabetes Research Foundation;   Joslin Diabetes Center;   University of Minnesota - Clinical and Translational Science Institute;   University of Colorado, Denver;   University of Michigan;   University of Toronto;   Feinberg School of Medicine, Northwestern University;   Albert Einstein College of Medicine;   Steno Diabetes Center Copenhagen;   Washington University School of Medicine;   University of Washington;   Emory University;   University of Calgary;   University of Alberta;   University of Texas Southwestern Medical Center;   BCDiabetes.Ca
Active, not recruiting

EUROASPIRE V Survey on Cardiovascular Disease Prevention and Diabetes

Conditions:   Cardiovascular Diseases;   Coronary Heart Disease
Intervention:   Other: There is no intervention
Sponsors:   Imperial College London;   European Society of Cardiology
Completed

Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation

Conditions:   Coronary Artery Disease;   Coronary Stent Occlusion
Interventions:   Other: Prolonged inflation;   Other: Rapid inflation
Sponsor:   Central Arkansas Veterans Healthcare System
Not yet recruiting

Comparison of Coronary Lithoplasty and Rotablation

Conditions:   Coronary Artery Disease;   Calcified Atheroma
Interventions:   Procedure: Rotablation;   Procedure: Coronary Lithoplasty
Sponsors:   University of Giessen;   Else Kröner-Fresenius Stiftung, Bad Homburg, Germany
Recruiting

PIONEER Trial:Hemodynamic Support With ECMO and IABP in Elective Complex High-risk PCI

Conditions:   Coronary Artery Disease;   Heart Failure
Intervention:   Device: extracorporeal membrane oxygenation
Sponsors:   Xijing Hospital;   The First Affiliated Hospital of Zhengzhou University;   Bethune International Peace Hospital;   Beijing Anzhen Hospital;   The Second Affiliated Hospital of Harbin Medical University;   General Hospital of Northern Theater Command
Not yet recruiting

An Evaluation of a Physiology-guided PCI Optimisation Strategy

Conditions:   Coronary Artery Disease;   Coronary Stenosis
Interventions:   Procedure: P.I.O.S.;   Diagnostic Test: Pre and post-PCI coronary physiology measurements
Sponsor:   NHS National Waiting Times Centre Board
Recruiting

LOwer Maintenance Dose TICagrelor in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention

Conditions:   Antiplatelet Therapy;   Coronary Artery Disease;   Percutaneous Coronary Intervention
Interventions:   Drug: Ticagrelor 90mg;   Drug: Ticagrelor 90mg/60mg;   Drug: Clopidogrel 75mg
Sponsor:   Beijing Anzhen Hospital
Not yet recruiting

The Value of CT-FFR Compared to CCTA or CCTA and Stress MPI in Low to Intermediate Risk ED Patients With Toshiba CT-FFR

Conditions:   Coronary Artery Disease;   Chest Pain;   Acute Coronary Syndrome;   Acute Myocardial Infarction
Intervention:   Device: Toshiba CT-FFR
Sponsors:   Northwell Health;   Toshiba America Medical Systems, Inc.
Enrolling by invitation

Use of Lexiscan for Myocardial Stress Perfusion Computed Tomography With a 3rd Generation Dual Source CT System

Conditions:   Cardiovascular Diseases;   Coronary Artery Disease
Intervention:   Drug: Lexiscan
Sponsors:   Medical University of South Carolina;   Astellas Pharma US, Inc.
Completed

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   NYU Langone Health;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University
Active, not recruiting

Motion and IntraCoronary Ecg Ischemia Development Study (MICE)

Condition:   Ischaemic Heart Disease
Intervention:   Procedure: Percutaneous coronary intervention with FFR measurement and intracoronary ECG registration
Sponsor:   University National Heart Hospital
Recruiting

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Population Health Research Institute;   Janssen Research & Development, LLC
Active, not recruiting

Synergistic Influence of Rivaroxaban on Inflammation and Coagulation Biomarkers in Patients With CAD and PAD on Aspirin Therapy

Conditions:   Coronary Artery Disease;   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban 2.5 Mg Oral Tablet;   Drug: Aspirin 81 mg
Sponsors:   LifeBridge Health;   Janssen Scientific Affairs, LLC
Not yet recruiting

Comparison of Pd/Pa Versus FFR in Intermediate Coronary Stenoses

Conditions:   Coronary Artery Disease;   Coronary Artery Stenoses
Interventions:   Diagnostic Test: measurement of FFR;   Diagnostic Test: measurement of Pd/Pa
Sponsors:   Leipzig Heart Institute GmbH;   Heart Center Leipzig - University Hospital
Not yet recruiting

Implementation of a Trimodal Prehabilitation Program as a Preoperative Optimization Strategy in Cardiac Surgery

Conditions:   Coronary Artery Disease;   Valvular Heart Disease
Intervention:   Behavioral: pre-habilitation
Sponsors:   Hospital Clinic of Barcelona;   Instituto de Salud Carlos III
Recruiting

Disrupt CAD III With the Shockwave Coronary IVL System

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:   Device: Lithotripsy
Sponsor:   Shockwave Medical, Inc.
Recruiting

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

Conditions:   Obesity;   Weight Loss;   CHD - Coronary Heart Disease
Interventions:   Other: Exercise;   Behavioral: Health Education;   Other: Exercise Compliance;   Dietary Supplement: Calorie-Restricted Diet;   Behavioral: Behavioral Modification;   Other: Weight-Loss Compliance;   Other: Dietary Counseling
Sponsors:   Wake Forest University Health Sciences;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Developing and Testing a Personalized Evidence-based Shared Decision-making Tool for Stent Selection

Condition:   Heart Diseases
Intervention:  
Sponsors:   University of Missouri, Kansas City;   Patient-Centered Outcomes Research Institute
Completed

Assessment of the Usefulness of Hemopatch in Coronary Artery Bypass Graft Surgery

Condition:   CHD - Coronary Heart Disease
Intervention:   Device: Medical Device Hemopatch-PEG-coated collagen patch
Sponsors:   Medical Universtity of Lodz;   Baxter Healthcare Corporation
Recruiting

PCI Alternative Using Sustained Exercise

Condition:   Cardiovascular Disease
Intervention:   Behavioral: Exercise Therapy
Sponsor:   VA Office of Research and Development
Active, not recruiting

MULTivessel Immediate Versus STAged RevaScularization in Acute Myocardial Infarction -The MULTISTARS AMI Trial

Conditions:   ST-elevation Myocardial Infarction;   Multivessel Coronary Disease
Interventions:   Procedure: Staged complete PCI;   Procedure: Immediate complete PCI;   Device: Synergy™ stent
Sponsor:   University of Zurich
Recruiting

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Conditions:   Coronary Artery Disease;   Ischemic Heart Disease;   Non ST Segment Elevation Myocardial Infarction
Interventions:   Device: Orbital Atherectomy;   Device: Balloon
Sponsors:   Cardiovascular Systems Inc;   Cardiovascular Research Foundation, New York
Recruiting

Cardiac Cath Lab Staff Radiation Exposure

Conditions:   Coronary Artery Disease;   Chronic Total Occlusion of Coronary Artery;   Percutaneous Coronary Intervention
Interventions:   Device: Robotic CTO PCI;   Procedure: Conventional (Manual) CTO PCI
Sponsor:   Corindus Inc.
Not yet recruiting

Myocardial Injury and Severe Pneumococcal Pneumonia

Conditions:   Pneumonia, Pneumococcal;   Myocardial Ischemia
Interventions:   Diagnostic Test: Echocardiography;   Diagnostic Test: Cardiac Magnetic resonance
Sponsor:   Alejandro Rodriguez Oviedo , MD
Recruiting

Minority Health Genomics and Translational Research Bio-Repository Database (MH-GRID)-2.0

Condition:   Hypertension
Intervention:  
Sponsors:   National Human Genome Research Institute (NHGRI);   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Relationship Between Fractional Flow Reserve/ Instantaneous Wave Free Ratio and Endothelial Wall Shear Stress

Conditions:   Stable Angina;   Acute Coronary Syndrome;   Coronary Artery Disease
Intervention:   Diagnostic Test: Fractional flow reserve
Sponsors:   Azienda Ospedaliera Città della Salute e della Scienza di Torino;   Politecnico di Torino
Recruiting

ISCHEMIA-Chronic Kidney Disease Trial

Conditions:   Cardiovascular Diseases;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia;   Kidney Disease;   End Stage Renal Failure on Dialysis
Interventions:   Procedure: Cardiac Catheterization;   Procedure: Coronary Artery Bypass Graft Surgery;   Procedure: Percutaneous Coronary Intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   NYU Langone Health;   New York University;   National Heart, Lung, and Blood Institute (NHLBI);   Duke University;   Stanford University;   Columbia University
Active, not recruiting

Custodiol-HTK (Histidine-tryptophan-ketoglutarate) Solution as a Cardioplegic Agent

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Coronary Disease;   Heart Diseases;   Valvular Heart Disease
Interventions:   Drug: Custodiol HTK;   Drug: Cold Blood Cardioplegia
Sponsors:   Marc Sakwa, MD;   Essential Pharmaceuticals, LLC
Completed

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

Conditions:   Cardiomyopathy;   Coronary Artery Disease;   Congestive Heart Failure;   Myocardial Infarction
Interventions:   Device: Implantable Cardioverter Defibrillator;   Other: Optimal Medical Therapy
Sponsor:   VA Office of Research and Development
Recruiting

EVOlocumab for Early Reduction of LDL-cholesterol Levels in Patients With Acute Coronary Syndromes (EVOPACS)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Evolocumab 140 mg/mL;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   Amgen;   University of Bern
Completed

Omega-3 for Depression and Other Cardiac Risk Factors - 2

Condition:   Depression
Interventions:   Drug: Omega-3 supplement;   Drug: Placebo
Sponsors:   Washington University School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Cardiovascular Events in Chronic Obstructive Pulmonary Disease Patients Initiating Olodaterol or Other Long-acting beta2 Agonists

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting

ST-segment Elevation Myocardial Infarction Clinical Pathway

Condition:   ST-segment Elevation Myocardial Infarction (STEMI)
Intervention:   Other: collection of clinical data
Sponsor:   Klinik für Kardiologie, Pneumologie und Angiologie
Recruiting

Insulin Resistance and Atherosclerosis in Women With Lupus

Conditions:   Systemic Lupus Erythematosus;   Insulin Resistance;   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed

Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study)

Conditions:   Atherosclerosis;   Cardiovascular Disease;   Vascular Diseases
Intervention:  
Sponsor:   National Institute on Aging (NIA)
Terminated

Clinical Evaluation of a Modular Extracorporeal Circulation Circuit

Conditions:   Coronary Artery Disease;   Aortic Valve Disease;   Mitral Valve Disease;   Aortic Aneurysm
Intervention:   Device: Modular Cardiopulmonary Bypass Circuit
Sponsor:   AHEPA University Hospital
Recruiting

Non-Interventional Registry Study to Evaluate the Performance and Safety of Roxwood Medical Catheters in Arteries of Participants With a Stenotic Lesion or Chronic Total Occlusion (CTO)

Conditions:   Chronic Total Occlusion;   Atherosclerosis;   Coronary Artery Disease;   Peripheral Artery Disease
Interventions:   Device: Roxwood Anchoring Catheters;   Drug: Acetylsalicylic Acid;   Drug: Heparin
Sponsor:   EKOS Corporation
Not yet recruiting

Study of Dutogliptin in Combination With Filgrastim in Post-Myocardial Infarction

Conditions:   Acute Myocardial Infarction;   Acute Myocardial Ischemia;   STEMI - ST Elevation Myocardial Infarction
Interventions:   Drug: Dutogliptin Tartrate;   Drug: Filgrastim Injectable Product;   Drug: Placebos
Sponsor:   Recardio, Inc.
Enrolling by invitation

Association of PeriOPerative Aspirin-ResisTance and CardioVascular Outcome

Condition:   Myocardial Injury
Intervention:  
Sponsor:   University Hospital Heidelberg
Not yet recruiting

Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride

Conditions:   Coronary Artery Disease;   Coronary Artery Stenoses;   Valve Regurgitation, Mitral;   Valve Regurgitation, Tricuspid
Interventions:   Drug: Exparel Injectable Product;   Drug: Bupivacaine Hydrochloride
Sponsors:   Kathirvel Subramaniam;   Pacira Pharmaceuticals, Inc
Recruiting

A Genome-Wide Scan For Quantitative Trait Loci of Serum Bilirubin - A Framingham Study

Condition:   Genetics
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Myocardial Infarction, COmbined-device, Recovery Enhancement Study

Conditions:   Acute Myocardial Infarction;   Coronary Artery Disease;   Acute Coronary Syndrome;   Myocardial Infarction
Intervention:   Device: Corrie Digital Health platform
Sponsors:   Johns Hopkins University;   Apple Inc.;   iHealth
Active, not recruiting

Angiotensin-(1-7) in Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Drug: Angiotensin 1-7;   Drug: Saline
Sponsor:   Milton S. Hershey Medical Center
Recruiting

Virtual Therapy as a Method Supporting the Cardiac Rehabilitation

Conditions:   Cardiovascular Diseases;   Coronary Artery Disease;   Depressive Symptoms;   Mood Disorders;   Anxiety State;   Stress
Interventions:   Behavioral: Cardiac rehabilitation;   Device: Virtual therapeutic support;   Behavioral: Standard therapeutic support
Sponsors:   University School of Physical Education in Wroclaw;   Foundation for Senior Citizen Activation SIWY DYM
Recruiting

Genetic Factors in Atherosclerosis

Condition:   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed

Assessment of Compliance With European and French Guidelines for the Management of Dyslipidaemias

Condition:   Patient With Dyslipidemia
Intervention:   Other: Detection of patients with dyslipidemia
Sponsor:   University Hospital, Montpellier
Recruiting

Effects of Nocturnal Nasal Oxygen on Biomarkers in Sleep Apnea Patients With Heart Failure

Conditions:   Sleep Apnea;   Heart Failure
Interventions:   Procedure: Nocturnal nasal oxygen;   Other: No nasal oxygen
Sponsor:   University of Maryland, Baltimore
Terminated

Evaluation of Arginine in Periodontal and Cardiovascular Disease

Conditions:   Metabolic Disorder;   Arginine; Hyperaminoaciduria
Intervention:   Other: Evaluation of arginine serum level
Sponsor:   University of Messina
Completed

Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care

Conditions:   Diabetes Mellitus;   Hypertension;   Coronary Artery Disease;   Atrial Fibrillation;   Stroke
Interventions:   Other: PHCVRS Intervention;   Other: Personal Health Record
Sponsor:   Korey Kennelty
Completed

Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity

Condition:   Adolescent Obesity
Intervention:   Other: Fructose + Glucose Beverage
Sponsors:   The Rogosin Institute;   Weill Medical College of Cornell University;   University of Missouri-Columbia
Recruiting

Secondary Prevention of Cardiovascular Disease in the Elderly Trial

Conditions:   Myocardial Infarction;   Cardiovascular Disease
Interventions:   Drug: Cardiovascular Polypill;   Drug: Treatment Prevention for Secondary CV
Sponsors:   Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III;   Charite University, Berlin, Germany;   Centre Hospitalier Universitaire de Besancon;   Wroclaw Medical University;   Semmelweis University;   General University Hospital, Prague;   Servicio Madrileño de Salud, Madrid, Spain;   London School of Hygiene and Tropical Medicine;   Ferrer Internacional S.A.;   Istituto Di Ricerche Farmacologiche Mario Negri
Recruiting

Evaluation of the Pharmacokinetics, Safety and Effects of NutriterraTM in Healthy Adults

Condition:   Healthy
Interventions:   Dietary Supplement: NutriterraTM;   Dietary Supplement: Placebo
Sponsors:   Nuseed Americas Inc.;   Nutrasource Diagnostics Inc.
Active, not recruiting

An Urban Trail Network and Cardiovascular Disease: A Natural Experiment

Conditions:   Cardiovascular Diseases;   Cardiovascular Risk Factor;   Diabetes Mellitus
Intervention:   Other: Urban Trail
Sponsors:   University of Manitoba;   St. Michael's Hospital, Toronto;   Ontario Agency for Health Protection and Promotion;   University of Toronto
Recruiting

The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment

Conditions:   Homocysteine;   Coronary Disease;   Angioplasty,Balloon,Coronary;   Contrast Media;   Nephropathy;   Hypertension
Interventions:   Drug: Enalapril Maleate Tablets(as the program-based antihypertension);   Drug: Enalapril Maleate and Folic Acid tablets(as the program-based antihypertension);   Drug: Placebo
Sponsor:   Fuling Central Hospital of Chongqing City
Completed

Monitoring of Nontraumatic Chest Pain Borne by the "Department of Emergency Help Medicalized" (SAMU)

Condition:   Chest Pain
Intervention:  
Sponsor:   French Cardiology Society
Completed

Genetic Predictors of Cardiovascular Disease

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Completed

Comparison of Minimal Versus Conventional Extracorporeal Circulation in Coronary Surgery

Condition:   Coronary Artery Bypass
Interventions:   Procedure: Coronary artery bypass grafting with the use of minimal invasive extracorporeal circulation;   Procedure: Coronary artery bypass grafting under conventional extracorporeal circulation
Sponsor:   AHEPA University Hospital
Active, not recruiting

Early Signs of Altitude Illness in Patients With COPD

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Diagnostic Test: Structured self-monitoring during an altitude ascent and stay at high altitude
Sponsors:   University of Zurich;   National Center of Cardiology and Internal Medicine, Kyrgyzstan
Recruiting

Cardiology Biobank Registry

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   Emory University
Recruiting

CES1 Carriers in the PAPI Study

Conditions:   Heart Diseases;   Coronary Disease;   Coronary Artery Disease;   Cardiovascular Diseases;   Myocardial Ischemia;   Artery Occlusion;   Aspirin Sensitivity;   Clopidogrel, Poor Metabolism of;   Platelet Dysfunction;   Platelet Thrombus
Interventions:   Drug: Clopidogrel;   Drug: Aspirin
Sponsor:   University of Maryland, Baltimore
Not yet recruiting

Comparing TR Band to Statseal in Conjunction With TR Band II

Conditions:   Arterial Occlusion;   Cardiovascular Diseases;   Atherosclerosis;   Hematoma;   Anticoagulant-induced Bleeding;   Coronary Artery Disease
Interventions:   Device: Statseal with TR Band;   Device: TR band only
Sponsor:   VA Long Beach Healthcare System
Enrolling by invitation

Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications

Conditions:   Lymphoma;   Chemotherapeutic Toxicity
Intervention:   Other: Blood test for determination of CHIP
Sponsors:   Sunnybrook Health Sciences Centre;   The Leukemia and Lymphoma Society;   Queen's University
Recruiting

Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy

Condition:   Node Positive HER2 Negative Breast Cancer
Interventions:   Other: Placebo;   Drug: Aspirin
Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI);   United States Department of Defense;   Bayer;   Canadian Cancer Trials Group
Recruiting

Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study.

Conditions:   Hip Fractures;   Hypotension on Induction;   Intraoperative Hypotension;   Acute Kidney Injury;   Myocardial Ischemia;   Wound Infection;   Perioperative/Postoperative Complications
Intervention:   Device: Continuous non-invasive blood pressure monitoring
Sponsors:   University Hospital Birmingham NHS Foundation Trust;   University of Warwick
Recruiting

ORthopaedic Trauma Anemia With Conservative Versus Liberal Transfusion

Condition:   Anemia
Intervention:   Biological: Blood and blood products for transfusion
Sponsors:   Indiana University;   Atlanta Medical Center;   Louisiana State University Health Sciences Center in New Orleans
Enrolling by invitation

Precision Medicine in Chinese Patients With Young Onset Diabetes

Condition:   Type 2 Diabetes
Interventions:   Other: Biogenetic explanation and endocrinologist intensive managment;   Other: Usual care management
Sponsor:   Chinese University of Hong Kong
Not yet recruiting

Treat Stroke to Target

Conditions:   Ischemic Stroke;   Transient Ischemic Attack;   Atherosclerotic Stenosis
Interventions:   Procedure: Target : 100 mg/dL (+/-10 mg/dL);   Procedure: 70 mg/dL
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Pfizer;   AstraZeneca;   Merck Sharp & Dohme Corp.
Completed

Feasibility of the "Heart-track" Rehabilitative Device Prototype

Conditions:   Cardiac Infarct;   Cardiac Event
Intervention:   Device: Heart Track
Sponsor:   Tan Tock Seng Hospital
Completed

ACS Registry - A Non-interventional Study to Estimate the Rates of Outcomes in ACS Patients in Moscow

Conditions:   Heart Attack;   Stroke;   Cardiovascular Death
Intervention:  
Sponsor:   AstraZeneca
Recruiting

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Active, not recruiting

Study to Weigh the Effect of Exercise Training on BONE (SWEET-BONE) Quality and Strength in Type 2 Diabetes

Condition:   Type 2 Diabetes
Intervention:   Other: supervised exercise training
Sponsors:   Metabolic Fitness Association, Italy;   University of Roma La Sapienza;   S. Andrea Hospital
Recruiting

Ticagrelor Compared to Clopidogrel in Acute Coronary Syndromes

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Ticagrelor 90mg;   Drug: Clopidogrel 75mg;   Drug: acetylsalicylic acid (ASA) 81mg
Sponsors:   McGill University Health Center;   Canadian Institutes of Health Research (CIHR)
Recruiting

FFR-CT to Detect the Absence of Hemodynamically Significant Lesions in Patients With High-risk Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Diagnostic Test: FFR-CT;   Diagnostic Test: FFRangio™
Sponsor:   Centre Hospitalier Universitaire Vaudois
Not yet recruiting

Inflammation Reduction by TREhalose AdminisTration

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Trehalose;   Drug: Normal saline
Sponsors:   Mashhad University of Medical Sciences;   National Institute for Medical Research Development;   Mashhad Razavi Hospital
Recruiting

Evolocumab in Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Evolocumab;   Drug: Placebo
Sponsors:   Johns Hopkins University;   Washington University School of Medicine
Recruiting

Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Biological: Apolipoprotein A-I [human] (apoA-I);   Other: Placebo
Sponsor:   CSL Behring
Recruiting

A Pharmacist-Led Hospital-Based Intervention to Support Medication Adherence Following Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:   Behavioral: Intervention cohort ('after' group)
Sponsors:   King's College London;   Guy's and St Thomas' NHS Foundation Trust
Completed

Real-world Use and Prognosis of Beta Blocker in Patients With Acute Coronary Syndrome in the Central China

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Henan Institute of Cardiovascular Epidemiology
Recruiting

Stress-Delta Biomarkers for Acute Coronary Syndrome Risk Stratification

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Duke University
Completed

French Observatory on the Management of Cardiogenic Shock in 2016

Condition:   Shock, Cardiogenic
Intervention:  
Sponsor:   French Cardiology Society
Completed

Rivaroxaban in Patients With Atrial Fibrillation Undergoing PCI

Conditions:   Non-valvular Atrial Fibrillation;   Acute Coronary Syndrome;   Percutaneous Coronary Intervention;   Antithrombotic Therapy
Intervention:  
Sponsors:   IHF GmbH - Institut für Herzinfarktforschung;   Bayer
Recruiting

Integrated Digitally Enhanced Care for Long-term Conditions- Asthma

Condition:   Asthma
Interventions:   Device: myAsthma Application;   Device: Lloyds Pharmacy Online Doctor
Sponsors:   my mhealth Ltd;   Expert Health Ltd;   CLAHRC Wessex
Withdrawn

A Study on the Metabolic Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With Stable Angina Pectoris

Condition:   Chronic Stable Angina Pectoris
Intervention:   Device: Near infrared spectroscopy
Sponsors:   Zhejiang Chinese Medical University;   The Third Affiliated hospital of Zhejiang Chinese Medical University;   The First Affiliated Hospital of Zhejiang Chinese Medical University
Recruiting

Genotyping GUided Antiplatelet theRapy in pAtieNts Treated With Drug Eluting stEnts (GUARANTEE)

Conditions:   Angina, Stable;   Acute Coronary Syndrome;   Drug-Eluting Stents;   Genotype
Intervention:   Genetic: CYP2C19 genotype testing
Sponsor:   Beijing Anzhen Hospital
Recruiting

A Study on the Heat Transport Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With Stable Angina Pectoris

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Device: Infrared thermal imaging
Sponsors:   Zhejiang Chinese Medical University;   The Third Affiliated hospital of Zhejiang Chinese Medical University;   The First Affiliated Hospital of Zhejiang Chinese Medical University
Recruiting

Cardiac Magnetic Resonance Imaging Strategy for the Management of Patients With Acute Chest Pain and Detectable to Elevated Troponin

Conditions:   Acute Coronary Syndrome;   Chest Pain
Interventions:   Procedure: Cardiac MRI;   Other: ACC/AHA Guideline adherent care
Sponsors:   Wake Forest University Health Sciences;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting

Comparison of High-dose Rosuvastatin Versus Low-dose Rosuvastatin Plus Ezetimibe on Carotid Plaque Inflammation in Patients With Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Carotid Atherosclerotic Plaque With Inflammation
Interventions:   Drug: high-dose rosuvastatin;   Drug: low-dose rosuvastatin plus ezetimibe
Sponsor:   Yuhan Corporation
Completed

Bivalirudin in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention.

Conditions:   Acute Coronary Syndrome;   Percutaneous Coronary Intervention;   Aging;   Anticoagulants and Bleeding Disorders
Interventions:   Drug: Bivalirudin;   Drug: Heparin
Sponsors:   The First Affiliated Hospital of Dalian Medical University;   Beijing Friendship Hospital
Recruiting

Prognosis of Patients With Acute Coronary Syndrome Complicated With Renal Insufficiency(PACS-RI)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Henan Institute of Cardiovascular Epidemiology
Recruiting

Smartphone Twelve Lead Electrocardiogram Utility In ST Elevation Myocardial Infarction

Condition:   ST Elevated Myocardial Infarction
Intervention:   Device: Alivecor Heart Monitor
Sponsor:   INTEGRIS Baptist Medical Center
Completed

Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:   Biological: Allogeneic umbilical cord mesenchymal stem cells
Sponsor:   Ever Supreme Bio Technology Co., Ltd.
Recruiting

French Cohort of Myocardial Infarction Evaluation

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsors:   Assistance Publique - Hôpitaux de Paris;   National Research Agency, France
Recruiting

MiSaver® Stem Cell Treatment for Heart Attack (Acute Myocardial Infarction)

Condition:   Myocardial Infarction
Intervention:   Biological: MiSaver®
Sponsors:   Honya Medical Inc;   Chung Shan Medical University
Recruiting

Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate

Conditions:   Anesthesia;   Transurethral Resection of Prostate Syndrome;   Myocardial Infarction
Intervention:   Other: general anesthesia or neuraxial anesthesia
Sponsor:   Chang Gung Memorial Hospital
Completed

Impact of Treating Severe Periodontitis on Inflammatory Activity of Atheromatous Plaques in Patients With Acute Myocardial Infarction (AMI)

Conditions:   Acute Myocardial Infarction;   Severe Periodontitis;   Carotid Atherosclerosis
Intervention:   Other: Periodontal treatment
Sponsors:   Assistance Publique - Hôpitaux de Paris;   National Research Agency, France
Recruiting

Outcomes of Patients With Venoarterial Extracorporeal Membrane Oxygenation

Conditions:   Cardiogenic Shock;   Cardiac Arrest
Intervention:   Device: VA ECMO
Sponsor:   Beijing Anzhen Hospital
Recruiting

The Pressure-controlled Intermittent Coronary Sinus Occlusion on VentrIcular PERformance Study

Condition:   Myocardial Infarction
Intervention:   Device: PICSO
Sponsors:   Oxford University Hospitals NHS Trust;   Miracor Medical SA
Not yet recruiting

Differences in Mortality and Morbidity in Patients Suffering a Time-critical Condition Between GEMS and HEMS

Conditions:   Ambulances;   Traumatic Brain Injury;   Acute Myocardial Infarction
Intervention:  
Sponsor:   Dalarna County Council, Sweden
Not yet recruiting

Mechanical Complications of Acute Myocardial Infarction

Conditions:   Post-Infarction Heart Rupture;   Post-Infarction Ventricular Septal Defect;   Post-Infarction Mitral Papillary Muscle Rupture
Intervention:   Procedure: Surgery for mechanical complications of acute myocardial infarction
Sponsor:   Maastricht University Medical Center
Recruiting

Hs-cTn - Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women

Conditions:   Myocardial Infarction;   Sex Differences;   High Sensitivity Troponin
Intervention:   Diagnostic Test: Introduction of a lower female hs-cTn cut-point
Sponsors:   BC Centre for Improved Cardiovascular Health;   Canadian Institutes of Health Research (CIHR)
Not yet recruiting

Aerobic Interval Training v/s Resistance Interval Training On Ejection Fraction In Stable Post MI Patients

Condition:   Myocardial Infarction
Interventions:   Other: Aerobic Interval Training;   Other: Aerobic + Resistive Interval Training
Sponsor:   Riphah International University
Completed

National Cardiogenic Shock Initiative

Conditions:   Cardiogenic Shock;   Acute Myocardial Infarction;   STEMI - ST Elevation Myocardial Infarction;   NSTEMI - Non-ST Segment Elevation MI;   Heart Attack
Intervention:  
Sponsors:   Henry Ford Health System;   Abiomed Inc.;   Chiesi Farmaceutici S.p.A.
Recruiting

Adherence to Prescribed Medication: Elucidating the Gap Between Guideline Recommendation and Real Life in Myocardial Infarction

Conditions:   Myocardial Infarction;   Adherence, Medication
Intervention:   Other: Investigating Adherence to Standard of Care Medication and Cardiac Rehabilitation
Sponsor:   Medical University of Vienna
Recruiting

A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Heart Attack

Condition:   Acute Myocardial Infarction
Intervention:   Drug: ACT-246475
Sponsor:   Idorsia Pharmaceuticals Ltd.
Completed

The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER)

Conditions:   ST-segment Elevation Myocardial Infarction;   Left Ventricular Remodeling
Interventions:   Drug: Hydrocortisone;   Drug: Placebo
Sponsors:   Iuliu Hatieganu University of Medicine and Pharmacy;   Romanian Governmental Funding (UEFISCDI)
Recruiting

Predicting Ventricular Tachyarrhythmias Following Acute ST Elevation Myocardial Infarction

Condition:   Risk Stratification
Intervention:   Other: Diagnostic
Sponsor:   Clinical Centre of Serbia
Recruiting

Apixaban Versus Warfarin in Patients With Left Ventricular (LV) Thrombus

Conditions:   Acute Myocardial Infarction;   Left Ventricular Thrombosis;   Anticoagulants and Bleeding Disorders
Interventions:   Drug: Apixaban Oral Tablet [Eliquis];   Drug: Warfarin
Sponsor:   Hadassah Medical Organization
Recruiting

Brilinta Clinical Experience Investigation

Condition:   Acute Coronary Syndrome, Old Myocardial Infarction
Intervention:  
Sponsor:   AstraZeneca
Recruiting

Monitoring Glucose Levels in Patients With Myocardial Infarction

Conditions:   Acute Coronary Syndromes;   Hyperglycemia;   Hypoglycemia
Intervention:   Device: OptiScanner®
Sponsors:   Lars Ryden;   Karolinska Institutet;   Swedish Heart Lung Foundation
Terminated

Post Infarction Exercise Effects on Myocardial Function Assessed by 2D Strain Ultrasound

Condition:   Myocardial Infarction
Intervention:   Other: Cardiac training program
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Active, not recruiting

Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI

Condition:   Acute Myocardial Infarction
Interventions:   Drug: LCZ696 (sacubitril/valsartan);   Drug: Ramipril;   Drug: Placebo of LCZ696;   Drug: Placebo of ramipril;   Drug: Valsartan;   Drug: Placebo of valsartan
Sponsor:   Novartis Pharmaceuticals
Recruiting

Impact of Morphine Treatment on Platelet Inhibition in Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Morphinhydrochloricum;   Drug: Metoclopramide;   Drug: Ticagrelor;   Drug: Isotonic sodium chloride
Sponsor:   University of Luebeck
Completed

Implantable Cardiac Monitors in High-Risk Post-Infarction Patients With Cardiac Autonomic Dysfunction

Conditions:   Myocardial Infarction;   Autonomic Nervous System Diseases
Intervention:   Device: Medtronic Reveal LINQ implantable cardiac monitor
Sponsors:   Klinikum der Universitaet Muenchen;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK);   Medtronic Bakken Research Center
Recruiting

French Registry of Acute ST-elevation or Non-ST-elevation Myocardial Infarction 2015

Condition:   Myocardial Infarction
Intervention:  
Sponsors:   French Cardiology Society;   Assistance Publique - Hôpitaux de Paris
Active, not recruiting

Effect of Vitamin D on Ventricular Remodeling in Patients With Acute Myocardial Infarction (VITDAMI)

Condition:   Myocardial Infarction
Interventions:   Drug: Calcifediol;   Drug: Placebo
Sponsors:   Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz;   Fondo de Investigacion Sanitaria;   Spanish Society of Cardiology
Recruiting

Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction

Conditions:   Myocardial Infarction;   Vascular Stiffness;   Heart Failure
Intervention:   Other: Imaging evaluation for vascular assessment
Sponsors:   University Hospital, Lille;   Fédération Française de Cardiologie;   Merck Sharp & Dohme Corp.
Not yet recruiting

French Observatory Syndromes Tako-Tsubo

Conditions:   Myocardial Necrosis;   Tako Tsubo Syndromes
Intervention:  
Sponsor:   French Cardiology Society
Completed

Effect of Doxycycline on Cardiac Remodelling in STEMI Patients

Conditions:   ST Elevation Myocardial Infarction;   Anterior Wall Myocardial Infarction;   Heart Failure;   Remodeling, Ventricular
Interventions:   Drug: Doxycycline 100Mg Capsule;   Drug: Placebo oral capsule
Sponsors:   Felix Chikita Fredy, MD;   National Cardiovascular Center Harapan Kita Hospital Indonesia
Recruiting

Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized Cardiac Patients

Conditions:   OSA;   Heart Failure;   Myocardial Infarction;   Arrhythmia, Cardiac
Intervention:   Device: Continuous Positive Airway Pressure
Sponsor:   Kaiser Permanente
Suspended

PRedictOrs, PHEnotypes and Timing of Obstructive Sleep Apnea in Acute Coronary Syndrome

Conditions:   ST Elevated Myocardial Infarction;   Sleep-Disordered Breathing;   Sleep;   NSTEMI - Non-ST Segment Elevation MI
Intervention:   Diagnostic Test: Polygraphy
Sponsor:   Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Recruiting

Biomarkers of Acute Stroke in Clinic

Conditions:   Ischemic Stroke;   Ischemia;   Atrial Fibrillation;   Transient Ischemic Attack;   Transient Cerebrovascular Events;   Thrombotic Stroke;   Stroke;   Stroke, Acute;   Stroke, Ischemic;   Stroke, Complication;   Stroke of Basilar Artery;   Atherosclerosis;   Atheroma;   Cardioembolic Stroke;   Cardiomyopathies;   Cardiovascular Stroke;   Thromboembolism
Intervention:   Diagnostic Test: ISCDX blood test
Sponsor:   Ischemia Care LLC
Not yet recruiting

MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms

Conditions:   Acute Coronary Syndrome;   Depression;   Myocardial Infarction;   Unstable Angina;   STEMI;   NSTEMI - Non-ST Segment Elevation MI
Interventions:   Other: Focus Group;   Other: Individual Interview
Sponsors:   Massachusetts General Hospital;   National Center for Complementary and Integrative Health (NCCIH)
Recruiting

Optimal Antithrombotic Therapy for ACS Patients Concomitant AF Undergoing New Generation DES Implantation

Conditions:   Acute Coronary Syndrome (ACS);   Non-valvular Atrial Fibrillation (NVAF)
Interventions:   Drug: Triple antithrombotic therapy;   Drug: Dual antithrombotc therapy
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting

Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention

Conditions:   Myocardial Infarction;   Acute Coronary Syndromes;   Unstable Angina
Interventions:   Drug: Short Tirofiban;   Drug: Eptifibatide;   Drug: Long Tirofiban
Sponsors:   Medicure;   SCRI Development Innovations, LLC
Completed

Anti-inflammatory Effect of Therapeutic Hypothermia in Out-hospital Cardiac Arrest Patients With Cardiogenic Shock

Condition:   Cardiac Arrest
Intervention:   Device: Therapeutic hypothermia group
Sponsor:   China Medical University Hospital
Completed

Efficacy and Safety of Adjunctive Cilostazol in Acute Myocardial Infarction Patients

Condition:   Acute Myocardial Infarction
Intervention:   Drug: antiplatelet therapy
Sponsor:   Korea University Guro Hospital
Recruiting

Complete Lesion Versus Culprit Lesion Revascularization

Condition:   Myocardial Infarction
Interventions:   Procedure: complete revascularization;   Procedure: Culprit revasularization
Sponsor:   Korea University Guro Hospital
Temporarily not available

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Conditions:   Acute Coronary Syndrome;   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting

French Registry of Acute Coronary Syndrome With or Without ST Elevation 2010

Conditions:   Myocardial Infarction;   Acute Coronary Syndrome
Intervention:  
Sponsor:   French Cardiology Society
Active, not recruiting

Home Hospital for Suddenly Ill Adults

Conditions:   Infection;   Heart Failure;   COPD;   Asthma;   Gout Flare;   Chronic Kidney Diseases;   Hypertensive Urgency;   Atrial Fibrillation Rapid;   Anticoagulants; Increased
Intervention:   Other: Home Hospitalization
Sponsor:   Brigham and Women's Hospital
Recruiting

Post-Acute Physician Home Visit Program

Condition:   A Patient Discharged From an Acute-care Hospital Who Had an Acute Illness
Intervention:   Other: Home visit
Sponsor:   Brigham and Women's Hospital
Completed

Remote Ischaemic Preconditioning in Transplantation (RIPTRANS)

Condition:   Transplant Dysfunction
Interventions:   Procedure: RIPC;   Procedure: Sham-RIPC
Sponsors:   Helsinki University Central Hospital;   Finska Läkaresällskapet (funding)
Recruiting