Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Fractional Flow Reserve Fax Registry

Condition:   Coronary Artery Disease
Intervention:   Diagnostic Test: Fractional Flow Reserve Measurement
Sponsors:   University of Erlangen-Nürnberg Medical School;   Abbott Vascular
Not yet recruiting - verified February 2017

Diagnostic Accuracy to Detect Hemodynamically Significant Stenosis by Non-invasive SURECardio CT-FFR

Condition:   Coronary Artery Disease
Intervention:   Device: CT-FFR. CTA. FFR
Sponsor:   Toshiba Medical Systems Corporation, Japan
Completed - verified February 2017

Effect of Antithrombotic Theatment in Patients With Coronary Heart Disease Complicated With Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Coronary Heart Disease
Intervention:  
Sponsor:   Henan Institute of Cardiovascular Epidemiology
Recruiting - verified February 2017

Implication of Cardiac Shock Wave Therapy on Coronary Heart Disease

Condition:   Cardiac Ischemia
Interventions:   Device: Cardiac shock wave therapy;   Other: Sham cardiac shock wave (Control group)
Sponsor:   Beijing Hospital
Recruiting - verified February 2017

Henry Ford Heart Score Randomized Trial: Rapid Discharge of Patients Evaluated for Possible Myocardial Infarction

Conditions:   Chest Pain;   Heart Attack;   Coronary Artery Disease
Intervention:   Other: Deferral of admission for stress test
Sponsor:   Henry Ford Health System
Completed - verified February 2017

Breathing-Induced Myocardial Oxygenation Reserve - Pilot Study

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   McGill University Health Center;   University Hospital Heidelberg;   Groote Schuur Hospital;   King's College London;   University of Wisconsin, Madison;   Jewish General Hospital
Recruiting - verified February 2017

Efficacy of Angiolite Stent vs a Second-generation Drug-eluting Stent Xience for Percutaneous Coronary Intervention

Conditions:   Coronary Artery Disease;   Drug-eluting Stent
Interventions:   Device: Angiolite;   Device: Xience
Sponsor:   Cardiva2 S.L.
Active, not recruiting - verified February 2017

System Delay and Clinical Outcome Among Chinese Patients With AMI Treated With Reperfusion Therapy (MOODY Study)

Condition:   Coronary Heart Disease
Intervention:   Procedure: Reperfusion
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Enrolling by invitation - verified February 2017

Optimal Duration of Clopidogrel in Second-Generation Drug-Eluting Stents

Condition:   Ischemic Heart Disease
Interventions:   Drug: 6-month dual anti-platelet therapy;   Drug: 12-month dual anti-platelet therapy;   Device: Zotarolimus eluting stent;   Device: Biolimus eluting stent
Sponsor:   Gangnam Severance Hospital
Completed - verified February 2017

Myocardial Injury and Severe Pneumococcal Pneumonia

Conditions:   Pneumonia, Pneumococcal;   Myocardial Ischemia
Interventions:   Diagnostic Test: Echocardiography;   Diagnostic Test: Cardiac Magnetic resonance
Sponsor:   Alejandro Rodriguez Oviedo
Not yet recruiting - verified February 2017

Assessment of Myocardial Ischemic-Reperfusion Injury During Off- and On- Pump CABG

Conditions:   Ischemic Heart Disease;   Coronary Artery Disease;   Ischemic Reperfusion Injury;   CABG
Interventions:   Procedure: On-Pump CABG.;   Procedure: Off-Pump CABG.;   Procedure: BH-CABG MSC.
Sponsor:   St. Petersburg State Pavlov Medical University
Recruiting - verified February 2017

Platelet Acetyl Coenzyme A Carboxylase Phosphorylation in Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome;   Coronary Thrombosis
Intervention:   Diagnostic Test: Platelet Acetyl Coenzyme A Carboxylase analysis in CAD
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Completed - verified February 2017

Invasive Validation of Non-invasive Central Blood Pressure Measurements Using Oscillometric Pulse Wave Analysis

Conditions:   Arterial Hypertension;   Coronary Heart Disease
Intervention:  
Sponsor:   Universitätsmedizin Mannheim
Active, not recruiting - verified February 2017

Effect of Preoperative Aspirin in Patients Undergoing Off-pump Coronary Artery Bypass Grafting

Conditions:   Coronary Artery Disease;   Aspirin
Interventions:   Drug: Aspirin;   Drug: vitamin C
Sponsor:   Medinet Heart Centre
Active, not recruiting - verified February 2017

Stress Echo 2020 - The International Stress Echo Study

Conditions:   Coronary Artery Disease;   Heart Failure;   Hypertrophic Cardiomyopathy;   Aortic Valve Disease;   Athletes Heart;   Tetralogy of Fallot;   Pulmonary Arterial Hypertension
Interventions:   Procedure: Left ventricular contractile reserve SE;   Procedure: B-lines SE;   Procedure: Left ventricular outflow tract gradient SE;   Procedure: Diastolic function SE;   Procedure: Mitral regurgitation SE;   Procedure: Pulmonary hemodynamics SE;   Procedure: Coronary flow reserve SE
Sponsors:   Fatebenefratelli Hospital;   Institute of Clinical Physiology, CNR, Pisa,Italy;   Salerno Hospital, Italy;   Monaldi Hospital, Napoli, Italy;   University of Pisa, Italy;   San Luca Hospital, Lucca, Italy;   Careggi University Hospital, Florence, Italy;   Federico II University, Napoli, Italy;   San Carlo Hospital, Potenza, Italy;   Royal Brompton & Harefield NHS Foundation Trust;   Ospedale dell'Angelo, Venezia-Mestre, Italy;   University of Parma;   Hospital Clinics, Trieste, Italy;   Rio Grande do Sul University Hospital, Porto Alegre, Brasil;   Hospital San José, Criciuma, Brasil;   Hospital San Vicente de Paulo, Passo Fundo, Brasil;   University of Belgrade;   University of Szeged, Hungary;   Elisabeth Hospital, Hodmezovasarhely, Hungary;   University of Padua, Italy;   Sandro Pertini Hospital, Rome, Italy;   Medical Center Hospital of the Republic of Kazakhstan, Astana, Kazakhstan;   Hospital Clinics, Bari, Italy;   Ospedale Nottola, Siena, Italy;   University of Catania, Italy;   Medika Cardiocenter, Saint Petersburg, Russian Federation
Recruiting - verified February 2017

Sapphire II PRO US Clinical Study

Conditions:   Coronary Artery Disease;   Coronary Disease;   Myocardial Ischemia;   Heart Diseases;   Arteriosclerosis;   Cardiovascular Diseases
Intervention:   Device: Sapphire II PRO
Sponsors:   OrbusNeich;   Icahn School of Medicine at Mount Sinai
Not yet recruiting - verified February 2017

Non-invasive Validation of Non-invasive Central Blood Pressure Measurements Using Oscillometric Pulse Wave Analysis

Conditions:   Arterial Hypertension;   Healthy Control;   Coronary Heart Disease;   Diabetes Mellitus
Intervention:  
Sponsor:   Universitätsmedizin Mannheim
Recruiting - verified February 2017

Validation of a Predictive Model of Coronary Fractional Flow Reserve in Patients With Intermediate Coronary Stenosis

Condition:   Coronary Stenosis
Intervention:   Diagnostic Test: Fractional Flow Reserve
Sponsor:   National Heart Centre Singapore
Recruiting - verified February 2017

Efficacy of Dotarem® (Gd-DOTA) Versus Magnevist® (Gd-DTPA) for Late Gadolinium Enhancement Cardiac Magnetic Resonance

Conditions:   Coronary Artery Disease;   Cardiomyopathy
Interventions:   Drug: Dotarem® (Gd-DOTA);   Drug: Magnevist® (Gd-DTPA)
Sponsors:   Dipan Shah;   Guerbet
Enrolling by invitation - verified February 2017

TIII Over TI in Subjects With Myocardial Infarction

Condition:   NSTEMI - Non-ST Segment Elevation MI
Intervention:   Other: Non interventional study
Sponsor:   University of Cologne
Completed - verified February 2017

The Impact of Depression and/or Anxiety on PCI Patients

Conditions:   Acute Coronary Syndrome;   MAjor Depressive Disorder;   Generalized Anxiety Disorder
Intervention:   Other: antidepressive and anti-anxiety therapy
Sponsors:   First Affiliated Hospital Xi'an Jiaotong University;   Shaanxi Provincial People's Hospital;   Xi'an Central Hospital;   Baoji Central Hospital;   Baoji People's Hospital;   General Hospital of Ningxia Medical University;   The People's Hospital of Ningxia;   Wuzhong People's Hospital;   The First Hospital of Lanzhou University;   LanZhou University;   First Affiliated Hospital of Xinjiang Medical University;   the People's Hospital of Xinjiang Uygur Autonomous Region;   The First People's Hospital of Kashgar Erea;   the First Division Hospital of Xinjiang Production and Construction Corps
Not yet recruiting - verified December 2016

Effect of Amlodipine Versus Amlodipine Combined With Atorvastatin on the Coronary Vasospastic Angina

Condition:   Quality of Life
Interventions:   Drug: Caduet 10Mg-20Mg Tablet;   Drug: NorvasC® 10 mg Tablets
Sponsor:   Kosin University Gospel Hospital
Not yet recruiting - verified February 2017

Is the Current Threshold for Diagnosis of "Abnormality", Including Non ST Elevation Myocardial Infarction, Using Raised Highly Sensitive Troponin Appropriate for a Hospital Population? The CHARIOT Study

Condition:   Myocardial Infarction
Intervention:  
Sponsor:   University Hospital Southampton NHS Foundation Trust
Not yet recruiting - verified February 2017

Comparison of Pharmacodynamic Effects of Tirofiban vs. Cangrelor in N-STEMI Patients Undergoing Percutaneous Coronary Intervention

Condition:   Non-ST Elevation Myocardial Infarction (NSTEMI)
Interventions:   Drug: Tirofiban;   Drug: Cangrelor
Sponsor:   Inova Health Care Services
Not yet recruiting - verified February 2017

Transplantation Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells With Intensive Atorvastatin in AMI Patients

Conditions:   Myocardial Infarction;   Stem Cell Transplantation;   Angioplasty, Transluminal, Percutaneous Coronary
Interventions:   Drug: Atorvastatin;   Drug: Intensive Atorvastatin;   Drug: Low dose BMMSC;   Drug: Middle dose BMMSC;   Drug: High dose BMMSC;   Drug: Transplantation
Sponsors:   Yuejin Yang;   Peking Union Medical College Hospital;   The First Hospital of Hebei Medical University;   Zunyi Medical College
Not yet recruiting - verified February 2017

Colchicine and Spironolactone in Patients With STEMI / SYNERGY Stent Registry

Condition:   ST Elevation Myocardial Infarction
Interventions:   Drug: Colchicine;   Drug: Spironolactone;   Device: SYNERGY Bioabsorbable Polymer Drug-Eluting Stent;   Drug: Colchicine-Placebo;   Drug: Spironolactone-Placebo
Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research (CIHR);   Boston Scientific Corporation
Not yet recruiting - verified February 2017

PCSK9 Inhibitors in the Progression of Aortic Stenosis

Condition:   Aortic Valve Stenosis
Interventions:   Drug: PCSK9 Inhibitor [EPC];   Drug: Placebos
Sponsor:   Seoul National University Hospital
Not yet recruiting - verified February 2017

Comparing TR Band to Statseal in Conjunction With TR Band

Conditions:   Arterial Occlusion;   Angina Pectoris;   Cardiovascular Diseases;   Atherosclerosis;   Hematoma;   Anticoagulant-Induced Bleeding;   Coronary Artery Disease
Interventions:   Device: StatSeal;   Device: TR Band
Sponsor:   VA Long Beach Healthcare System
Not yet recruiting - verified February 2017

Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris

Conditions:   Refractory Angina Pectoris;   Gene Transfer;   Coronary Artery Disease
Interventions:   Drug: AdvVEGF-D;   Drug: Control Rx
Sponsors:   Kuopio University Hospital;   Queen Mary University of London;   University College, London;   Medizinische Universitaet Wien;   Servicio Madrileño de Salud, Madrid, Spain;   FinVector Vision Therapies Oy;   Śląski Uniwersytet Medyczny w Katowicach;   Rigshospitalet, Denmark;   Euram Limited
Not yet recruiting - verified January 2017

Heart Rate Variability as a Predictor of Ischemic Heart Disease

Condition:   Acute Coronary Syndrome
Intervention:   Other: Heart rate variability
Sponsor:   University of Iowa
Completed - verified February 2017

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY 1142524 in Patients After Acute Myocardial Infarction With Left-ventricular Dysfunction

Condition:   Myocardial Infarction
Interventions:   Drug: BAY1142524;   Drug: Placebo
Sponsor:   Bayer
Recruiting - verified February 2017

Alirocumab in Patients With Acute Myocardial Infarction

Conditions:   Myocardial Infarction;   Hypercholesterolemia
Interventions:   Drug: alirocumab;   Drug: placebo
Sponsors:   Virginia Commonwealth University;   Regeneron Pharmaceuticals;   Sanofi
Recruiting - verified February 2017

Comprehensive Treatment of Angina in Women With Microvascular Dysfunction

Conditions:   Angina Pectoris;   Coronary Microvascular Disease
Interventions:   Dietary Supplement: Diet;   Behavioral: Training;   Drug: Medication (with statin and ACE-inhibition)
Sponsors:   Bispebjerg Hospital;   University Hospital Bispebjerg and Frederiksberg;   Cambridge Weight Plan Limited
Recruiting - verified February 2017

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment - at the Time of Coronary Angiography - Affect Management Strategy, Hospital Costs and Outcomes?

Conditions:   Chest Pain;   Stable Angina;   Acute Coronary Syndrome;   Non ST Segment Elevation Acute Coronary Syndrome
Intervention:   Device: Routine Measurement of FFR
Sponsors:   University Hospital Southampton NHS Foundation Trust;   Liverpool Heart and Chest Hospital NHS Foundation Trust
Recruiting - verified February 2017

Role of Podocan and Wnt Pathway Regulatory Molecules in Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Bassett Healthcare;   Baylor University
Recruiting - verified February 2017

Early Vascular Healing in Acute Coronary Syndrome Patients With Different Doses of Rosuvastatin

Condition:   Acute Coronary Syndrome
Interventions:   Drug: High dose Rosuvastatin;   Drug: Low dose Rosuvastatin
Sponsor:   Nanjing First Hospital, Nanjing Medical University
Recruiting - verified February 2017

Moderato System: A Double-Blind Randomized Trial

Conditions:   Hypertension Resistant to Conventional Therapy;   Bradycardia;   Atrioventricular Block
Interventions:   Device: BackBeat-PHC ON;   Device: BackBeat-PHC OFF
Sponsors:   BackBeat Medical Inc;   MGH Echo Core Lab;   MLM Medical Labs GmbH;   nabios GmbH
Recruiting - verified February 2017

Trhombus Aspiration in Hyperglycemic ST-elevation myocardiAl InfarcTIon

Condition:   Hyperglycemia
Intervention:   Device: percutaneous coronary intervention
Sponsor:   Second University of Naples
Completed - verified February 2017

COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome Trials

Conditions:   Stable Angina;   Unstable Angina;   STEMI;   NSTEMI;   Coronary Disease
Interventions:   Device: COMBO-Stent;   Drug: Clopidogrel, Vitamin K Antagonist, Rivaroxaban, Dabigatran;   Device: Any drug eluting stent oder bare metal sent;   Drug: ASA, Clopidogrel, Vitamin K Antagonist, Rivaroxaban, Dabigatran
Sponsors:   IHF GmbH - Institut für Herzinfarktforschung;   OrbusNeich
Withdrawn - verified February 2017

Observational Registry on Acute Coronary Syndromes in Campania

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Federico II University
Not yet recruiting - verified February 2017

Chemical Renal Ethanol Sympatholysis Under CT Guidance Use for the Control of Therapy-Resistant Hypertension

Conditions:   Hypertension Resistant to Conventional Therapy;   Kidney Failure, Chronic
Interventions:   Procedure: Renal sympathicolysis;   Procedure: Ambulatory Blood Pressure Monitoring;   Radiation: Magnetic Resonance Angiography;   Biological: Blood test
Sponsor:   University Hospital, Grenoble
Recruiting - verified February 2017

Optimizing Timing of CABG in Patients Presenting With ACS and Treated With Ticagrelor

Condition:   Coronary Artery Disease
Interventions:   Procedure: PRU guided CABG;   Procedure: CABG per standard of care;   Device: VerifyNow assay;   Drug: Ticagrelor
Sponsor:   St. Michael's Hospital, Toronto
Recruiting - verified February 2017

Supernormal Oxygen Delivery for Elderly Surgical Patients

Condition:   Femoral Fractures
Interventions:   Procedure: SV maximization;   Procedure: supernormal DO2
Sponsor:   Guangzhou First Municipal People’s Hospital
Recruiting - verified February 2017

Coronary Bifurcation Lesions Treated With Biguard Stent System

Condition:   Coronary Artery Disease
Interventions:   Device: Biguard sirolimus-eluting bifurcation stent system;   Device: Sirolimus-eluting stent system
Sponsor:   Nanjing First Hospital, Nanjing Medical University
Terminated - verified February 2017

Colchicine in Percutaneous Coronary Intervention

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome
Intervention:   Drug: Colchicine vs Placebo
Sponsors:   VA Office of Research and Development;   New York University School of Medicine
Recruiting - verified February 2017

Get Going: Accelerometer-Based Intervention to Promote Physical Activity in Frail Older Adults

Conditions:   Coronary Artery Disease;   Heart Failure
Interventions:   Behavioral: Intervention;   Behavioral: Control
Sponsors:   American College of Cardiology;   Alliance for Academic Internal Medicine
Recruiting - verified November 2016

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified February 2017

A Comparison of an Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent for Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome
Interventions:   Device: Orsiro;   Device: Xience
Sponsors:   University Hospital Inselspital, Berne;   University of Lausanne Hospitals
Recruiting - verified February 2017

Treadmill CV Safety Study

Condition:   Stable Angina
Interventions:   Drug: AMG 334;   Drug: Placebo
Sponsor:   Amgen
Active, not recruiting - verified February 2017

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

Conditions:   Secondary Prevention;   Stroke;   Ischemic Heart Disease;   Coronary Heart Disease
Interventions:   Drug: Acetylsalicylic Acid (Asprin, BAYE4465);   Drug: Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
Sponsor:   Bayer
Recruiting - verified February 2017

Effect of ACE-Inhibition on Microvascular Function in Women With Assessed Microvascular Dysfunction

Condition:   Microvascular Angina
Interventions:   Drug: Ramipril (ACE-inhibitor);   Drug: placebo
Sponsor:   Bispebjerg Hospital
Completed - verified February 2017

Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS

Condition:   Acute Coronary Syndrome
Interventions:   Drug: dalcetrapib;   Drug: Placebo
Sponsors:   DalCor Pharmaceuticals;   The Montreal Health Innovations Coordinating Center (MHICC);   Medpace, Inc.;   Roche Molecular Systems, Inc
Recruiting - verified February 2017

Evaluation of Antiplatelet Effects and Safety of Intraoperative Administration of Ticagrelor Versus Clopidogrel

Condition:   Coronary Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   Yongjian Wu
Recruiting - verified February 2017

Korean Coronary Overlapping Stenting Registy

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   The Catholic University of Korea
Recruiting - verified February 2017

RIGENERA 2.0 Trial

Conditions:   Anterior Myocardial Infarction;   Heart Failure
Interventions:   Drug: rhu G-CSF;   Drug: optimal standard of care;   Procedure: Myocardial Contrast Echocardiography
Sponsor:   Catholic University of the Sacred Heart
Active, not recruiting - verified February 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

Stress Ulcer Prophylaxis in the Intensive Care Unit

Conditions:   Gastrointestinal Bleeding;   Stress Ulcers
Interventions:   Drug: Pantoprazole;   Other: Saline (0.9%)
Sponsors:   Dr. Morten Hylander Møller;   Rigshospitalet, Denmark;   Copenhagen Trial Unit, Center for Clinical Intervention Research
Recruiting - verified February 2017

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2016

Comparison of Low-Dose, Standard-Dose Ticagrelor and Clopidogrel for Inhibition of Platelet Reactivity in Patients With Acute Coronary Syndromes

Condition:   Acute Coronary Syndrome
Interventions:   Drug: ticagrelor;   Drug: clopidogrel
Sponsors:   Seung-Jung Park;   AstraZeneca;   Roche Pharma AG;   KBM pharm
Active, not recruiting - verified February 2017

Two-stent vs Provisional Stenting Techniques for Patients With Complex Coronary Bifurcation Lesions

Condition:   Coronary Artery Disease
Interventions:   Procedure: Two-stenting technique;   Procedure: Simple stenting technique;   Procedure: Percutaneous Coronary Intervention
Sponsor:   Nanjing First Hospital, Nanjing Medical University
Recruiting - verified February 2017

Thoratec Corporation HeartMate PHP™ Cardiogenic Shock Trial

Condition:   Cardiogenic Shock
Intervention:   Device: HeartMate PHP
Sponsors:   Thoratec Corporation;   St. Jude Medical
Terminated - verified February 2017

Real Life Long-term Adherence to Ticagrelor After PCI for Acute Coronary Syndromes

Condition:   Acute Coronary Syndrome (ACS)
Intervention:   Drug: Ticagrelor
Sponsor:   IHF GmbH - Institut für Herzinfarktforschung
Completed - verified February 2017

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified February 2017

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2017

A Trial of Low-dose Adjunctive alTeplase During prIMary PCI

Condition:   Myocardial Infarction
Interventions:   Drug: Alteplase;   Other: Placebo
Sponsors:   NHS Greater Glasgow and Clyde;   University of Glasgow;   National Institute for Health Research, United Kingdom
Recruiting - verified September 2016

Intravascular Ultrasound Guided Drug Eluting Stent Implantation in "All-comers" Coronary Lesions

Condition:   Coronary Artery Disease
Interventions:   Procedure: Angiography;   Procedure: IVUS;   Procedure: DES implantation
Sponsor:   Nanjing First Hospital, Nanjing Medical University
Recruiting - verified February 2017

Prospective, Single-arm, Multi Centre Observations Ultimaster Des Registry

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Terumo Europe N.V.
Recruiting - verified July 2016

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

Conditions:   Cardiomyopathy;   Coronary Artery Disease;   Congestive Heart Failure;   Myocardial Infarction
Interventions:   Device: Implantable Cardioverter Defibrillator;   Other: Optimal Medical Therapy
Sponsor:   VA Office of Research and Development
Recruiting - verified February 2017

Elixir Medical Clinical Evaluation of the DESolve Myolimus Eluting Bioresorbable Coronary Stent System - DESolve I Trial

Condition:   Coronary Artery Disease
Intervention:   Device: DESolve Novolimus Eluting Bioresorbable Coronary Scaffold
Sponsor:   Elixir Medical Corporation
Active, not recruiting - verified February 2017

Elixir Medical Clinical Evaluation of the DESolve® Novolimus Eluting Bioresorbable Coronary Scaffold System - The DESolve Nx Trial

Condition:   Coronary Artery Disease
Intervention:   Device: DESolve Novolimus Eluting Bioresorbable Coronary Scaffold System
Sponsor:   Elixir Medical Corporation
Active, not recruiting - verified February 2017

Objective Randomised Blinded Investigation With Optimal Medical Therapy of Angioplasty in Stable Angina

Condition:   Stable Angina
Intervention:   Procedure: Coronary angioplasty
Sponsors:   Imperial College London;   Volcano Corporation
Recruiting - verified February 2017

Developing and Testing a Personalized Evidence-based Shared Decision-making Tool for Stent Selection

Condition:   Heart Diseases
Intervention:  
Sponsors:   University of Missouri, Kansas City;   Patient-Centered Outcomes Research Institute
Completed - verified February 2017

EXCELLA Post-Approval Study

Condition:   Coronary Artery Disease
Interventions:   Device: Subjects receiving DESyne Novolimus Eluting CSS - Arm A;   Device: Subjects receiving DESyne BD Novolimus Eluting CSS - Arm B
Sponsor:   Elixir Medical Corporation
Active, not recruiting - verified February 2017

Physical Activity Daily - An Internet-Based Walking Program for Patients With Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Behavioral: Telephone counseling;   Behavioral: Internet-based walking program
Sponsors:   University of Michigan;   National Institute on Aging (NIA)
Recruiting - verified February 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

On-treatment PLAtelet Reactivity-guided Therapy Modification FOR ST-segment Elevation Myocardial Infarction

Condition:   Acute ST-elevation Myocardial Infarction
Intervention:   Drug: Antiplatelet Regimen Modification (aspirin or ticagrelor)
Sponsor:   Clinical Centre of Serbia
Recruiting - verified February 2017

Early Smoking Reduction or Cessation by Means of no Nicotine Electronic Cigarette Added to Standard Counselling.

Conditions:   Cancer;   Myocardial Infarction
Interventions:   Device: No nicotine electronic cigarette;   Other: Standard counseling
Sponsor:   European Institute of Oncology
Completed - verified December 2015

Reducing Radioisotope Dose: the Half-Dose CZT Study

Condition:   Coronary Artery Disease
Intervention:   Other: Half-dose isotope for NuclearStressTest
Sponsors:   S.M.Chang, MD;   The Methodist Hospital System
Recruiting - verified February 2017

CPR Training: Video Self-Instruction Kit or Video-Only

Conditions:   Cardiovascular Risk Factors;   Coronary Disease;   Cardiac Arrest
Interventions:   Other: CPR Training using the Family and Friends CPR Anytime Video Self Instruction;   Other: Implementation of a Hospital-based CPR Training Model;   Other: Follow-up prompting to encourage skill retention
Sponsor:   University of Pennsylvania
Active, not recruiting - verified February 2017

Prevention of Serious Adverse Events Following Angiography

Conditions:   Acute Renal Failure;   Kidney Disease;   Coronary Artery Disease
Interventions:   Drug: IV isotonic saline;   Drug: IV isotonic bicarbonate;   Drug: N-acetylcysteine;   Drug: Placebo
Sponsors:   VA Office of Research and Development;   The George Institute
Recruiting - verified February 2017

Venous Function in Cardiovascular Disease Patients

Condition:   Myocardial Infarction
Interventions:   Behavioral: interval training day 1;   Behavioral: Moderate exercise day 2;   Behavioral: Control day 3
Sponsor:   Norwegian University of Science and Technology
Completed - verified February 2017

Sirolimus-eluting Stents With Biodegradable Polymer Versus an Everolimus-eluting Stents

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Myocardial Infarction
Interventions:   Device: Sirolimus-eluting stent with a bioresorbable polymer (Orsiro);   Device: Everolimus-eluting stent with a durable polymer
Sponsors:   University Hospital Inselspital, Berne;   Biotronik AG;   University of Bern
Active, not recruiting - verified February 2017

Elixir Medical Clinical Evaluation of the Novolimus-Eluting Coronary Stent System: A Randomized Study "EXCELLA II STUDY"

Condition:   Coronary Artery Disease
Interventions:   Device: Medtronic Endeavor Coronary Stent System;   Device: DESyne BD Novolimus Stent System;   Device: DESyne Novolimus Stent System
Sponsor:   Elixir Medical Corporation
Active, not recruiting - verified February 2017

An Observational Study of TNKase in Patients Enrolled in the National Registry of Myocardial Infarction 4 and 5 (POST)

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Genentech, Inc.
Completed - verified February 2017

Acute Chest Pain Treatment and Evaluation (ACTION) Study

Condition:   Chest Pain
Intervention:   Procedure: Stress nuclear scan
Sponsors:   Singapore General Hospital;   National Medical Research Council (NMRC), Singapore;   National Heart Centre Singapore
Completed - verified February 2017

Determinants of Cardiac Risk Factor Modification in Latinos With Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2017

Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study)

Conditions:   Atherosclerosis;   Cardiovascular Disease;   Vascular Diseases
Intervention:  
Sponsor:   National Institute on Aging (NIA)
Active, not recruiting - verified January 26, 2017

Exercise-training Before Coronary Artery Bypass Graft (CABG)

Conditions:   Angina;   Coronary Artery Disease
Intervention:   Behavioral: Exercise training
Sponsor:   Norwegian University of Science and Technology
Completed - verified February 2017

Clinical and Economic Consequences of Left Atrial Bipolar Radiofrequency Ablation of Persistent and Permanent Atrial Fibrillation During Cardiac Surgery

Conditions:   Atrial Fibrillation;   Coronary Artery Disease
Intervention:   Procedure: bipolar radiofrequency ablation of persistent and permanent AF
Sponsors:   Medtronic Bakken Research Center;   Medtronic
Terminated - verified February 2017

High-intensity Exercise Training in Patients With Post-infarction Heart Failure

Conditions:   Heart Failure;   Myocardial Infarction
Interventions:   Behavioral: Moderate intensity exercise training;   Behavioral: High intensity exercise training
Sponsor:   Norwegian University of Science and Technology
Completed - verified February 2017

Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)

Condition:   Coronary Artery Disease
Intervention:   Drug: pexelizumab in conjunction with CABG
Sponsors:   Alexion Pharmaceuticals;   Procter and Gamble
Active, not recruiting - verified February 2017

Women's Health Trial: Feasibility Study in Minority Populations

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Diseases;   Myocardial Ischemia;   Postmenopause
Intervention:   Behavioral: diet, fat-restricted
Sponsors:   National Cancer Institute (NCI);   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2017