Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Biomime Stent in All-comers PCI Patients Registry

Condition:   Coronary Artery Disease
Intervention:   Device: percutaneous coronary intervention
Sponsor:   Azienda Ospedaliero Universitaria Maggiore della Carita
Recruiting - verified March 2015

Pericardial Fat and Inflammation in HIV Patients and Controls

Conditions:   Coronary Artery Disease;   Human Immunodeficiency Virus (HIV)
Intervention:  
Sponsor:   University of Cincinnati
Recruiting - verified January 2015

Aerobic Exercise and Oxygen Uptake Efficiency Slope in Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Other: Aerobic exercise training
Sponsor:   Hospital TotalCor
Completed - verified March 2015

An Assessment of the Glider Balloon in Complex Lesions

Condition:   Coronary Artery Disease
Intervention:   Device: PTCA Balloon Angioplasty
Sponsor:   TriReme Medical, LLC
Recruiting - verified March 2015

Epigenetic Reprogramming of Monocytes in Patients With Coronary Atherosclerosis

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Radboud University;   Canisius-Wilhelmina Hospital
Recruiting - verified March 2015

Relationship Between Diet, Lifestyle, and the Severity of Coronary Artery Disease

Conditions:   Dietary Habits;   Coronary Artery Disease;   Lifestyle
Intervention:   Behavioral: Survey
Sponsor:   New York University School of Medicine
Recruiting - verified March 2015

Sequential Coronary CT-angiography and Biomarkers

Conditions:   Coronary Artery Disease;   Atherosclerosis
Interventions:   Radiation: Coronary CT-angiography;   Other: Assesment of biomarkers involved in atherothrombosis
Sponsor:   Maastricht University Medical Center
Recruiting - verified March 2015

Acute Myocardial Infarction Quality Assurance Project

Conditions:   Myocardial Infarction;   Death;   Heart Failure
Interventions:   Other: Quality Assurance Implementation;   Other: Standard of Care
Sponsor:   Dr. Derek Exner
Recruiting - verified March 2015

Transversus Abdominis Plane Versus Caudal Block for Pediatrics

Condition:   Lower Abdominal Surgery
Interventions:   Other: Transversus abdominis plane block;   Other: Caudal block;   Drug: Bupivacaine
Sponsor:   Mansoura University
Recruiting - verified March 2015

Ciclosporin to Reduce Reperfusion Injury in Primary PCI

Condition:   Myocardial Reperfusion Injury
Interventions:   Drug: Ciclosporin;   Drug: Saline
Sponsors:   Newcastle-upon-Tyne Hospitals NHS Trust;   National Institute for Health Research Newcastle Biomedical Research Centre;   Newcastle University
Not yet recruiting - verified March 2015

Cardiovascular, Renal and Metabolic Profile in Patients With Acute Myocardial Infarction (REN-ACS)

Conditions:   Hypertension, Renovascular;   Renal Artery Stenosis;   Myocardial Infarction
Interventions:   Procedure: renal artery angiography;   Procedure: coronarography;   Procedure: coronary angioplasty;   Procedure: pulse wave velocity measurement;   Procedure: body composition monitoring
Sponsor:   Grigore T. Popa University of Medicine and Pharmacy
Recruiting - verified March 2015

Study Comparing the MiStent SES Versus the XIENCE EES Stent

Condition:   Coronary Stenosis
Interventions:   Device: MiStent;   Device: XIENCE EES
Sponsors:   ECRI bv;   Micell Technologies;   Stentys
Not yet recruiting - verified February 2015

Safety and Efficacy of the CRE8 Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Artery Lesions

Condition:   Coronary Artery Disease
Intervention:   Device: CRE8 sirolimus-eluting stent
Sponsor:   CID S.p.A.
Recruiting - verified March 2015

Safety and Efficacy of the CRE8 Stent for the Treatment of De Novo Coronary Artery Lesions

Condition:   Coronary Artery Disease
Interventions:   Device: CRE8 sirolimus-eluting stent;   Device: RESOLUTE zotarolimus-eluting stent
Sponsor:   CID S.p.A.
Recruiting - verified March 2015

CSCC_ASC Therapy in Patients With Severe Heart Failure

Condition:   Clinical Patient Safety of Allogeneic Stem Cell Therapy
Intervention:   Biological: Allogeneic adipose derived stem cells (CSCC_ASC)
Sponsor:   JKastrup
Recruiting - verified March 2015

Endothelial Function-guided Therapy Compared to Usual Care in Patients With NOCAD

Condition:   Coronary Atherosclerosis
Intervention:  
Sponsor:   Itamar-Medical, Israel
Not yet recruiting - verified March 2015

Eggs as Part of a Healthy Breakfast

Condition:   Cardiovascular Diseases
Interventions:   Other: Eggs - 2 per day for breakfast;   Other: 1 packet of oatmeal per day
Sponsor:   University of Connecticut
Active, not recruiting - verified March 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Not yet recruiting - verified March 2015

Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers

Conditions:   Myocardial Infarction;   Inflammation;   Acute Coronary Syndrome (ACS);   Reperfusion Injury
Interventions:   Biological: Salmonella typhi vaccine (Typhim Vi®);   Drug: Oxygen (Oxymask®);   Drug: Atorvastatin
Sponsors:   Karolinska Institutet;   University Hospital, Linkoeping
Recruiting - verified March 2015

Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Condition:   Hypercholesterolemia
Intervention:   Biological: Evolocumab
Sponsor:   Amgen
Enrolling by invitation - verified March 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified March 2015

The OCT SORT-OUT VIII Study

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Myocardial Infarction
Interventions:   Device: Everolimus eluting bioresorbable polymer stent;   Device: Biolimus eluting bioresorbable polymer stent
Sponsors:   Aarhus University Hospital Skejby;   Biosensors International;   Boston Scientific Corporation
Recruiting - verified March 2015

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified March 2015

Randomized Comparison of MynxGrip Vascular Closure Device and Manual Compression for Closure After Femoral Access Angiography. The Closure Devices Used in Every Day Practice Study, CLOSE-UP III Trial

Condition:   Coronary Disease
Interventions:   Device: MynxGrip;   Other: Manual compression
Sponsors:   Aarhus University Hospital Skejby;   Vingmed Danmark A/S
Recruiting - verified March 2015

Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial

Condition:   Coronary Disease
Interventions:   Device: computed tomography perfusion guided treatment;   Device: Fractional flow reserve guided treatment
Sponsor:   Young-Hak Kim, MD, PhD
Recruiting - verified March 2015

Canadian SCAD Study

Condition:   Spontaneous Coronary Artery Dissection
Intervention:  
Sponsors:   Cardiology Research UBC;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified March 2015

DOCTOR Compare - A Study in the "DOCTOR" Series (Does Optical Coherence Tomography Optimize Revascularization?"

Conditions:   Coronary Disease;   Myocardial Infarction;   Atherosclerosis
Interventions:   Procedure: Comparison of OCT scans;   Procedure: Comparison of Intra Vascular Optical Coherence Tomography Systems for Assessment of Coronary Tissue, Stents and Scaffolds - DOCTOR Compare
Sponsor:   Aarhus University Hospital Skejby
Completed - verified March 2015

Pharmacokinetics of Everolimus in ABSORB BVS in Patients With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Intervention:   Device: Coronary artery stenting: ABSORB BVS
Sponsor:   Abbott Vascular
Active, not recruiting - verified March 2015

Is Efficacy of PLAtelet Aggregation Inhibition by Ticagrelor Mediated P2Y12 Blockade Dependent Upon Endogenous Endothelial Nitric OXide?

Condition:   Acute Coronary Syndome
Interventions:   Other: Blood Test;   Other: EndoPAT - endothelial assessment
Sponsor:   Jennifer Rossington
Not yet recruiting - verified March 2015

The Hellenic Postprandial Lipemia Study (HPLS)

Conditions:   Coronary Heart Disease;   Dyslipidemia
Intervention:  
Sponsor:   Hellenic College of Treatment of Atherosclerosis
Recruiting - verified June 2014

Randomized Comparison of ExoSeal® and Angio-Seal Vascular Closure Devices: The CLOSE-UP II Trial

Condition:   Coronary Disease
Interventions:   Device: Exoseal closure device;   Device: Angioseal closure device
Sponsors:   Aarhus University Hospital Skejby;   Cordis Corporation;   St. Jude Medical
Recruiting - verified March 2015

The Does Optical Coherence Tomography Optimize Revascularization (DOCTOR) Recross Study

Condition:   Coronary Disease
Interventions:   Device: Xience Prime Stent;   Device: Medtronic Resolute Integrity stent;   Procedure: Angiography;   Procedure: OCT
Sponsors:   Aarhus University Hospital Skejby;   St. Jude Medical;   Medtronic
Recruiting - verified March 2015

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Losmapimod 7.5 mg twice daily;   Drug: Placebo twice daily
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Recruiting - verified March 2015

Heartstrong Pilot Program

Condition:   Acute Myocardial Infarction
Interventions:   Behavioral: Social Influence;   Behavioral: Electronic Pill Bottles;   Behavioral: Financial Incentives
Sponsor:   University of Pennsylvania
Recruiting - verified April 2014

DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury

Condition:   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   University of Edinburgh;   AstraZeneca
Recruiting - verified March 2015

Efficacy and Safety of New Generation Drug Eluting Stents Associated With an Ultra Short Duration of Dual Antiplatelet Therapy. Design of the Short Duration of Dual antiplatElet Therapy With SyNergy II Stent in Patients Older Than 75 Years Undergoing Percutaneous Coronary Revascularization.

Conditions:   Stable Angina;   Silent Myocardial Ischemia;   Acute Coronary Syndrome
Interventions:   Procedure: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Synergy II stent;   Procedure: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Omega stent;   Procedure: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Rebel stent
Sponsor:   Ceric Sàrl
Recruiting - verified December 2014

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Treatment 3 months DAPT;   Drug: Treatment 12 months DAPT
Sponsor:   Diagram B.V.
Recruiting - verified March 2015

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL112;   Biological: Placebo
Sponsor:   CSL Behring
Recruiting - verified March 2015

HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt

Conditions:   Coronary Arteriosclerosis;   Non ST Segment Elevation Acute Coronary Syndrome
Interventions:   Device: OrbusNeich Combo stent™;   Device: Everolimus Eluting Stent (EES)
Sponsors:   OrbusNeich;   OrbusNeich Medical K.K.;   Duke Clinical Research Institute
Recruiting - verified March 2015

A Phase II Study of Androgen Deprivation Therapy With or Without PD 0332991 in RB-Positive Metastatic Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: PD 0332991;   Drug: Bicalutamide;   Drug: Zoladex;   Drug: Lupron Depot
Sponsors:   University of Michigan Cancer Center;   University of Utah;   Vanderbilt-Ingram Cancer Center;   Dana-Farber Cancer Institute;   Johns Hopkins University;   Thomas Jefferson University
Recruiting - verified March 2015

Registry for Estimation of Warfarin and Rivaroxaban in Atrial Fibrillation Patients With Coronary Stent Implantation

Conditions:   Coronary Artery Disease;   Atrial Fibrillation;   Stroke;   Fetal Blood Loss
Intervention:   Drug: Warfarin or Rivaroxaban
Sponsors:   Fujita Health University;   Bayer Yakuhin, Ltd.
Recruiting - verified March 2015

Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD

Condition:   Coronary Artery Dissection, Spontaneous
Interventions:   Drug: ramipril;   Drug: rosuvastatin;   Drug: placebo
Sponsor:   Cardiology Research UBC
Recruiting - verified July 2014

Routine Versus Selective Use of FFR to Guide PCI

Conditions:   Acute Coronary Syndrome;   Coronary Atherosclerosis;   Angina, Unstable
Intervention:   Device: Fractional Flow Reserve (FFR)
Sponsors:   Cardiology Research UBC;   Provincial Health Services Authority
Terminated - verified March 2015

Prevalence of Morbidity in Newly Diagnosed type2 Diabetes in Adults

Conditions:   Type2 Diabetes Mellitus;   Complications
Intervention:   Other: no specific treatment
Sponsors:   University of Algiers;   National Institute of public Health, Algeria;   Ain-Taya's hospital, Algiers;   Parnet's teaching Hospital, Algiers;   Mustapha Pacha's teaching hospital, Algiers;   Birtraria's teaching hospital, Algiers;   Bab el Oued's teaching hospital, Algiers
Completed - verified March 2015

Multiple Electrode Aggregometry & Clopidogrel Resistance

Conditions:   Type 2 Diabetes Mellitus (T2DM);   Coronary Artery Disease (CAD);   Myocardial Infraction
Intervention:  
Sponsor:   Elpen Pharmaceutical Co. Inc.
Completed - verified March 2015

The TRansendocardial Stem Cell Injection Delivery Effects on Neomyogenesis STudy (The TRIDENT Study)

Condition:   Chronic Ischemic Left Ventricular Dysfunction Secondary to Myocardial Infarction.
Intervention:   Biological: Allogeneic hMSCs
Sponsors:   Joshua M Hare;   The EMMES Corporation
Active, not recruiting - verified March 2015

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Ticagrelor 90 mg;   Drug: Ticagrelor placebo
Sponsor:   AstraZeneca
Recruiting - verified March 2015

Specimen Procurement& Data Collection Protocol for The Rapid Evaluation of Possible Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:   Other: OBSERVATIONAL REGISTRY
Sponsor:   Henry Ford Health System
Recruiting - verified March 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified March 2015

High-sensitivity Troponin in Cardiac Surgery

Conditions:   Heart; Dysfunction Postoperative, Cardiac Surgery;   Myocardial Infarction;   Myocardial Injury
Intervention:   Other: serum concentration changes cardiac biomarkers
Sponsors:   Onze Lieve Vrouw  Hospital;   Roche Farma, S.A
Completed - verified March 2015

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified March 2015

Application for Self-Monitoring of Cardiovascular Risk

Condition:   Coronary Artery Disease Which Requires Percutaneous Coronary Intervention(Balloon and/or Stent Treatment).
Intervention:   Device: Self Monitoring Software Application
Sponsor:   Mayo Clinic
Active, not recruiting - verified March 2015

Influence of FFR on the Clinical Outcome After Percutaneous Coronary Intervention

Condition:   Coronary Disease
Intervention:  
Sponsors:   Inje University;   Seoul National University Hospital;   Keimyung University Dongsan Medical Center;   Ulsan University Hospital;   Hallym University Medical Center;   Kangdong Sacred Heart Hospital;   Busan Veterans General Hospital;   Myongji Hospital;   Chungbuk National University Hospital;   Hanyang University;   Dong-A University Hospital;   Gyeongsang National University Hospital
Recruiting - verified March 2015

Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rosuvastatin;   Drug: Atorvastatin
Sponsor:   Centro Cardiopatici Toscani
Recruiting - verified March 2015

Partners and Alerts: A Study of Social Forces in Medication Adherence

Condition:   Acute Myocardial Infarction (AMI)
Interventions:   Behavioral: Electronic Pill Bottle tracking;   Behavioral: Adherence Messaging;   Behavioral: Social Influence;   Behavioral: Medication schedule alarms
Sponsor:   University of Pennsylvania
Recruiting - verified June 2013

High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction
Intervention:   Device: High-sensitivity troponin I assay
Sponsors:   University of Edinburgh;   NHS Lothian;   NHS Greater Glasgow and Clyde;   Abbott Diagnostics Division
Recruiting - verified March 2015

PROMISE Substudy to Assess For Effective Dose of Radiation (PROMISE-SAFER) Specific Aim 3b

Conditions:   Chest Pain;   Coronary Artery Disease;   Angina
Intervention:  
Sponsors:   Kaiser Permanente;   Columbia University
Active, not recruiting - verified March 2015

Effect of Isoflurane on Tissue Doppler Imaging of Mitral Annulus During Cardiac Surgery

Conditions:   Valvular Heart Disease;   Ischemic Heart Disease
Intervention:   Drug: Isoflurane
Sponsor:   Konkuk University Medical Center
Completed - verified March 2015

The Treatment of Coronary Artery Lesions Using the PRO-Kinetic Energy Cobalt-Chromium, Bare-Metal Stent

Condition:   Coronary Artery Disease
Intervention:   Device: PRO-Kinetic Energy Stent
Sponsor:   Biotronik AG
Terminated - verified March 2015

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound

Condition:   Hypercholesterolemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo
Sponsor:   Amgen
Active, not recruiting - verified March 2015

Angiogenesis and Fibrosis in Aortic Stenosis

Conditions:   Aortic Stenosis;   Fibrosis;   Neovascularization, Pathologic
Interventions:   Procedure: Cardiac MRI scan;   Radiation: CT-PET scan;   Procedure: Echocardiogram;   Radiation: CT-coronary angiogram scan;   Procedure: Aortic Valve Replacement
Sponsor:   University of Edinburgh
Recruiting - verified March 2015

Angiogenesis and Fibrosis in Myocardial Infarction

Conditions:   Myocardial Infarction;   Fibrosis;   Neovascularization, Pathologic
Interventions:   Procedure: Cardiac MRI scan;   Radiation: CT-PET scan;   Radiation: CT-coronary angiogram
Sponsor:   University of Edinburgh
Recruiting - verified March 2015

Automated Hovering to Improve Medication Adherence Among Myocardial Infarction Patients (Heartstrong)

Condition:   Patients With Principal or Secondary Diagnosis Code of Intrntl Classification of Diseases, 9th Revision, (ICD-9-CM) 410 (Except When 5th Digit Was 2)
Intervention:   Behavioral: Electronic Pill Bottle, Incentives, Social Influence
Sponsor:   University of Pennsylvania
Active, not recruiting - verified April 2013

Mindful Hearts Study

Conditions:   Cardiovascular Disease;   Psychological Stress;   Stroke;   Coronary Artery Disease
Interventions:   Behavioral: Mindfulness Based Stress Reduction;   Behavioral: Health Education Program
Sponsor:   Department of Veterans Affairs
Recruiting - verified March 2015

Lipoprotein Apheresis in Refractory Angina Study

Conditions:   Refractory Angina;   Raised Lipoprotein(a)>50mg/dL or >500mg/L
Interventions:   Other: Lipoprotein Apheresis;   Other: Sham Apheresis
Sponsors:   Imperial College London;   National Institute for Health Research, United Kingdom
Active, not recruiting - verified February 2013

An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction

Conditions:   Acute Coronary Syndrome;   Non-ST Elevation (NSTEMI) Myocardial Infarction;   Acute ST Segment Elevation Myocardial Infarction;   Angina, Unstable
Intervention:   Drug: Oxygen
Sponsors:   Karolinska Institutet;   Swedish Heart Lung Foundation;   Swedish Foundation for Strategic Research;   The Swedish Research Council
Recruiting - verified March 2015

Kinetics of Troponin and BNP in Breast Cancer Chemotherapy With Adriamycin and Trastuzumab

Condition:   Breast Cancer
Intervention:  
Sponsor:   Mayo Clinic
Enrolling by invitation - verified March 2015

REgister of Myocardial Infarction Patients Treated by the NOVAra STE-MI Network

Condition:   Acute Myocardial Infarction
Intervention:   Device: Primary PCI
Sponsor:   Azienda Ospedaliero Universitaria Maggiore della Carita
Recruiting - verified March 2015

Clinical Evaluation of the CADence Device in Detection of Coronary Artery Diseases

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   AUM Cardiovascular, Inc.
Recruiting - verified March 2015

Complete vs Culprit-only Revascularization to Treat Multi-vessel Disease After Primary PCI for STEMI

Conditions:   Acute Myocardial Infarction;   Coronary Artery Disease;   Percutaneous Coronary Intervention
Intervention:   Procedure: Complete Revascularization Strategy
Sponsor:   Population Health Research Institute
Recruiting - verified March 2015

Does Optical Coherence Tomography Optimise Results of Stenting

Condition:   Acute Coronary Syndromes
Intervention:   Procedure: OCT
Sponsor:   Centre Hospitalier Universitaire de Besancon
Recruiting - verified March 2015

Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasis

Conditions:   Psoriasis;   Vascular Inflammation;   Coronary Atherosclerosis
Interventions:   Biological: Adalimumab;   Other: Placebo
Sponsors:   Innovaderm Research Inc.;   Abbott;   Montreal Heart Institute
Active, not recruiting - verified September 2014

Single Long vs Two Short Overlapping Bioabsorbable Polymer DES

Condition:   Coronary Artery Disease
Intervention:   Device: implantation of a bioabsorbable polymer DES
Sponsor:   Azienda Ospedaliero Universitaria Maggiore della Carita
Recruiting - verified March 2015

The Impact of Gratitude on Biology and Behavior in Persons With Heart Disease

Conditions:   Myocardial Infarction;   Unstable Angina
Intervention:  
Sponsors:   Massachusetts General Hospital;   University of California, Berkeley
Completed - verified March 2015

Optimal Physiologic Intravascular Ultrasound Imaging Criteria After Drug Eluting Stent Implantation

Condition:   Coronary Disease
Intervention:  
Sponsors:   Inje University;   Seoul National University Hospital
Completed - verified March 2015

HeartTrends Heart Rate Variability (HRV) Algorithm for the Diagnosis of Myocardial Ischemia

Condition:   Ischemic Heart Disease
Intervention:  
Sponsor:   Sheba Medical Center
Completed - verified March 2015

Citalopram for Sx/Util in Acute Coronary Syndrome Patients

Condition:   Acute Coronary Syndrome
Intervention:   Drug: Citalopram
Sponsor:   Henry Ford Health System
Not yet recruiting - verified August 2012

Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery

Conditions:   Congenital Heart Disease;   Heart Valve Disease
Intervention:   Drug: simvastatin
Sponsor:   Sun Yat-sen University
Recruiting - verified March 2015

SmartTouch Catheter in Ablation of Ventricular Tachycardia

Conditions:   Arrhythmias, Cardiac;   Tachycardia, Ventricular;   Myocardial Infarction;   Cardiomyopathies
Intervention:  
Sponsors:   Hospital Universitario Virgen de la Arrixaca;   Biosense Webster, Inc.
Active, not recruiting - verified March 2015

Depression Care for Hospitalized Coronary Heart Disease Patients: Prospective Cohort Study

Conditions:   Coronary Heart Disease;   Depression
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   University Hospital Muenster
Active, not recruiting - verified March 2015

Evaluating New Radiation Techniques for Cardiovascular Imaging

Condition:   Coronary Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified March 2015

Antiplatelet Therapy Guided by Thrombelastography in Patients With Acute Coronary Syndromes (TEGCOR Study)

Conditions:   Thrombosis;   Coronary Artery Disease
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel
Sponsor:   Indiana University
Recruiting - verified March 2015

SONOlysis in Risk REduction of Symptomatic and Silent Brain infarCtions dUring Cardiac surgEry

Conditions:   Coronary Artery Bypass Graft Redo;   Heart Valve Diseases
Interventions:   Procedure: sonolysis;   Procedure: cardiac surgery
Sponsors:   University Hospital Ostrava;   Palacky University;   Ministry of Health, Czech Republic
Recruiting - verified March 2015

BIOFLOW-III All-comers Orsiro Safety and Performance Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:  
Sponsor:   Biotronik AG
Active, not recruiting - verified March 2015

Study to Improve Long Term Vein Graft Patency After Coronary Bypass Surgery by Using a Novel Endoscopic Harvesting Technique

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Baylor Research Institute;   Maquet Cardiovascular
Completed - verified March 2015

Coronary Hybrid Revascularisation Study

Condition:   Significant Coronary Artery Disease
Intervention:   Procedure: Combined CABG and PCI
Sponsor:   Aarhus University Hospital Skejby
Recruiting - verified March 2015

The Nordic-Baltic Bifurcation Study IV

Condition:   Coronary Artery Disease
Interventions:   Procedure: Implantation of coronary stent in bifurcation lesion;   Procedure: Implantation of coronary stent in bifurcation lesion
Sponsors:   Niels Ramsing Holm;   Johnson & Johnson
Active, not recruiting - verified March 2015

Prevalence and Long-term Impact of Non-atherosclerotic CAD

Condition:   Myocardial Infarction
Intervention:  
Sponsors:   Cardiology Research UBC;   University of British Columbia
Recruiting - verified March 2015

VH-IVUS Plaque Composition Analysis By Fractional Flow Reserve

Condition:   Coronary Disease
Intervention:  
Sponsors:   Inje University;   Seoul National University Hospital
Completed - verified March 2015

Diagnostic Performances of Computed TomographIc Coronary Angiography and Intravascular Ultrasound

Condition:   Diagnosis Coronary Artery Disease
Intervention:   Procedure: diagnostic procedures CCTA, CAG, IVUS and FFR
Sponsors:   Seoul National University Hospital;   Inje University
Completed - verified March 2015

Ticagrelor and Aspirin for the Prevention of Cardiovascular Events After Coronary Artery Bypass Surgery

Condition:   Coronary Artery Disease
Interventions:   Drug: ticagrelor;   Drug: Placebo
Sponsors:   Cardiology Research UBC;   University of British Columbia
Completed - verified March 2013

Impact of Coronary Artery Bypass Graft (CABG) Surgery on Skeletal Muscle Mass and Insulin Sensitivity, Followed by Exercise Intervention

Condition:   Coronary Artery Disease
Intervention:   Other: exercise training
Sponsor:   Hasselt University
Completed - verified March 2015

Validation/Evaluation of Multimodal Imaging Combining 3D Ultrasound and Stress Myocardial Scintigraphy in the Diagnosis of Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Coronary Disease
Interventions:   Procedure: Stress ultrasound;   Procedure: Scintigraphy;   Procedure: Coronary angiography
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Withdrawn - verified March 2015

A Study of the Safety and Efficacy of Injectable Thymosin Beta 4 for Treating Acute Myocardial Infarction

Conditions:   Acute Myocardial Infarction;   ST Elevation Myocardial Infarction;   STEMI
Interventions:   Drug: Drug: Placebo;   Drug: Drug: Injectable Thymosin beta 4
Sponsor:   RegeneRx Biopharmaceuticals, Inc.
Suspended - verified November 2012

Sodium Bicarbonate and N-Acetylcysteine for Nephroprotection in Acute Myocardial Infarction

Conditions:   Acute Myocardial Infarction;   Acute Kidney Injury
Interventions:   Drug: Sodium bicarbonate plus NAC;   Drug: Saline hydration plus NAC
Sponsors:   Catholic University of the Sacred Heart;   Policlinico Casilino ASL RMB
Completed - verified March 2015

Omega 3 Fatty Acid Efficiency for Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting

Conditions:   Ischemic Heart Disease;   Atrial Fibrillation
Interventions:   Drug: Omega-3 fish oil emulsion (Omegaven);   Drug: Intralipid
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Terminated - verified March 2015

Rubidium-82 Position Emission Computed Tomography (PET) Versus Gated, Rest / Stress Technetium 99-m SPECT

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Heart Disease
Interventions:   Other: SPECT imaging;   Other: PET imaging
Sponsors:   Hartford Hospital;   Bracco Diagnostics, Inc
Completed - verified July 2012

Data Aquisition for Optimization of Coronary Artery Disease Algorithm

Condition:   Coronary Artery Disease
Intervention:   Device: ProtoCAD
Sponsors:   Coloplast A/S;   Rigshospitalet, Denmark
Completed - verified March 2015

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified March 2015

A Study to Evaluate 3 Different Dosing Regimens of Mipomersen Administered Via Subcutaneous Injections to Healthy Volunteers

Condition:   Healthy Volunteer
Interventions:   Drug: mipomersen;   Drug: Placebo
Sponsors:   Genzyme, a Sanofi Company;   Isis Pharmaceuticals
Completed - verified March 2015

Stress Management and Biomarkers of Risk in Cardiac Rehabilitation

Condition:   Coronary Heart Disease
Interventions:   Behavioral: SMT-enhanced Cardiac Rehabilitation;   Behavioral: Standard Cardiac Rehabilitation
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified March 2015

The Nordic Bifurcation Study III

Condition:   Coronary Artery Disease
Intervention:   Procedure: Percutaneous coronary intervention (PCI)
Sponsors:   Niels Ramsing Holm;   Johnson & Johnson
Active, not recruiting - verified March 2015

A Simple Dietary Message to Improve Dietary Quality for Metabolic Syndrome

Condition:   Metabolic Syndrome
Intervention:   Behavioral: Dietary Intervention
Sponsors:   University of Massachusetts, Worcester;   National Institutes of Health (NIH)
Completed - verified March 2015

AngelMed for Early Recognition and Treatment of STEMI

Conditions:   Acute Myocardial Infarction (AMI);   Coronary Occlusion;   Acute Coronary Syndrome
Intervention:   Device: AngelMed Guardian System
Sponsors:   Angel Medical Systems;   Symbios Clinical
Active, not recruiting - verified July 2013

INDICOR The Paclitaxel-Eluting PTCA-Balloon Catheter in Combination With a Cobalt-Chromium Stent

Condition:   Coronary Heart Diseases
Interventions:   Device: Drug Eluting Balloon SeQuent Please;   Device: Drug Eluting Balloon SeQuent Please
Sponsors:   Ralf Degenhardt, PhD;   B. Braun Melsungen AG
Active, not recruiting - verified March 2015

A Phase 1 Safety Study of the Intravenous Administration of Thymosin Beta in Healthy Volunteers

Conditions:   Myocardial Infarction;   Myocardial Ischemia
Interventions:   Drug: thymosin beta 4;   Other: Placebo
Sponsor:   RegeneRx Biopharmaceuticals, Inc.
Completed - verified March 2015

Risk Score Alerts for Chest Pain Care

Conditions:   Chest Pain;   Acute Myocardial Infarction
Intervention:   Other: Electronic risk alerts
Sponsors:   Harvard Vanguard Medical Associates;   Brigham and Women's Hospital
Completed - verified March 2015

French Registry of Acute Coronary Syndrome

Condition:   Acute Myocardial Infarction
Intervention:   Other: Blood sample
Sponsors:   Assistance Publique - Hôpitaux de Paris;   French Cardiology Society
Active, not recruiting - verified March 2015

A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease

Condition:   Moderate Risk of CVD
Interventions:   Drug: Aspirin (Acetylsalicylic acid, BAYE4465);   Drug: Placebo
Sponsor:   Bayer
Active, not recruiting - verified March 2015

Paclitaxel Eluting Balloon Versus Drug Eluting Stent in Native Coronary Artery Stenoses of Diabetic Patients

Conditions:   Coronary Stenosis;   Diabetes Mellitus
Interventions:   Device: Paclitaxel Eluting Balloon;   Device: paclitaxel eluting stent;   Device: bare metal stent
Sponsors:   Heart Centre Rotenburg;   B. Braun Medical SA
Active, not recruiting - verified March 2015

PEPCAD I. The Paclitaxel-Eluting PTCA-Balloon Catheter to Treat Small Vessel

Condition:   Coronary Stenosis
Intervention:   Device: Drug Eluting Balloon
Sponsors:   Heart Centre Rotenburg;   B. Braun Melsungen AG;   Clinical Research Institute, Center for Cardiovascular Disease Rotenburg a.d.F.
Completed - verified March 2015

hsCRP in Japan Statin Treatment Against Recurrent Stroke (J-STARS hsCRP)

Condition:   Ischemic Stroke
Intervention:   Drug: Statin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University;   Osaka University
Active, not recruiting - verified March 2015

Assessing Myocardial Blood Flow and Blood Flow Reserve by Transoesophageal Echocardiography (TEE)

Condition:   Coronary Artery Disease
Interventions:   Drug: SonoVue;   Drug: Optison
Sponsor:   University Hospital, Basel, Switzerland
Withdrawn - verified March 2015

SB-480848 In Subjects With Coronary Heart Disease

Condition:   Atherosclerosis
Intervention:   Drug: SB-480848
Sponsor:   GlaxoSmithKline
Completed - verified March 2015

Testosterone and Myocardial Perfusion in CHD

Condition:   Coronary Heart Disease
Intervention:   Drug: Testosterone undecanoate
Sponsors:   Imperial College London;   Organon
Completed - verified October 2005

Japan Statin Treatment Against Recurrent Stroke (J-STARS)

Condition:   Ischemic Stroke
Intervention:   Drug: Pravastatin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University
Active, not recruiting - verified March 2015

Autoimmunity and Coronary Artery Disease - Ancillary to CARDIA

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Diseases
Intervention:  
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified March 2015

Behavioral Factors in Coronary Heart Disease

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Metabolic Syndrome X
Intervention:  
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified February 2015

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