Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Optical Coherence Tomography in Patients With Acute Myocardial Infarction and Nonobstructive Coronary Artery Disease

Condition:   Myocardial Infarction
Intervention:   Device: OCT and CMR imaging
Sponsor:   Institute of Cardiology, Warsaw, Poland
Recruiting - verified May 2016

The SHINE-CTO Trial

Conditions:   Coronary Artery Disease;   Chronic Total Occlusion of Coronary Artery;   Percutaneous Transluminal Coronary Angioplasty
Interventions:   Procedure: Chronic Total Occlusion Percutaneous Coronary Intervention;   Procedure: Sham Procedure
Sponsor:   North Texas Veterans Healthcare System
Enrolling by invitation - verified May 2016

Intra-patient Study With Polymer Free Drug Eluting Stent Versus Abluminal Biodegradable Polymer Drug Eluting Stent With Early OCT (Optical Coherence Tomography) Follow up

Condition:   Coronary Artery Disease
Interventions:   Device: Coroflex® ISAR Drug-eluting stent;   Device: Ultimaster® Drug-eluting stent
Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   B.Braun Surgical SA
Not yet recruiting - verified March 2016

Stress-MRI Assessment After Right Coronary Artery CTO Recanalization

Conditions:   Ischemic Heart Disease;   Coronary Atherosclerosis;   Coronary Artery Disease;   Coronary Artery Stenosis
Interventions:   Procedure: CTO coronary angioplasty;   Drug: Optimal medicamentous treatment;   Procedure: Stress-MRI
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Completed - verified May 2016

Association Between Telomere Length and Risk of Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Fourth Military Medical University
Completed - verified May 2016

Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency Department

Condition:   Syncope
Intervention:  
Sponsor:   University of Turin, Italy
Recruiting - verified May 2016

Epidemiology of Risk Factors for Hospital-acquired Pneumonia (HAP) in Intensive Care Unit (ICU) Patients

Condition:   Ventilator-Associated Pneumonia
Intervention:   Other: Epidemiology od HAP
Sponsor:   University Hospital Olomouc
Completed - verified May 2016

Prophylactic Substrate Ablation in Post-myocardial Patients Undergoing Defibrillator Implantation.

Conditions:   Heart Failure;   Myocardial Infarction;   Ventricular Tachycardia
Intervention:   Procedure: Ventricular tachycardia substrate ablation
Sponsors:   Spyridon Deftereos;   Biosense Webster, Inc.
Not yet recruiting - verified May 2016

Late Stent Strut Apposition and Coverage After Drug-Eluting Stent Implantation by OCT in Patients With AMI

Conditions:   Coronary Artery Disease;   Coronary Disease;   Myocardial Ischemia;   Arterial Occlusive Diseases;   Arteriosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Vascular Diseases
Interventions:   Device: Everolimus-Eluting stent;   Device: Zotarolimus-Eluting stent
Sponsor:   Keimyung University Dongsan Medical Center
Recruiting - verified May 2016

Optimizing Strategy of Coronary Revascularization in Patients With Multivessel Lesions Combined Heart Failure

Condition:   Heart Failure Due to Coronary Artery Disease
Interventions:   Procedure: Coronary Artery Bypass Grafting;   Procedure: Percutaneous Coronary Intervention;   Procedure: Hybrid Coronary Revascularization
Sponsor:   Shanghai Jiao Tong University School of Medicine
Recruiting - verified May 2016

CT Perfusion Added to CT Angiography

Condition:   Angina Pectoris
Intervention:   Procedure: Cardiac computed tomography
Sponsor:   Universitaire Ziekenhuizen Leuven
Not yet recruiting - verified May 2016

STrategic Reperfusion in Elderly Patients Early After Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Drug: Tenecteplase;   Drug: Clopidogrel;   Procedure: Coronary angiography;   Procedure: Primary PCI
Sponsors:   Katholieke Universiteit Leuven;   Boehringer Ingelheim;   Life Sciences Research Partners;   Fund for Clinical Cardiovascular Research at LRD
Not yet recruiting - verified May 2016

Self-apposing Stentys Stents Registry

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Azienda Ospedaliera Città della Salute e della Scienza di Torino
Not yet recruiting - verified May 2016

Intracoronary Thrombus Detection by Magnetic Resonance Imaging

Conditions:   Angina Pectoris;   Angina, Stable;   Angina, Unstable;   Myocardial Infarction
Interventions:   Other: Magnetic Resonance Imaging;   Device: Optical Coherence Tomography;   Procedure: Invasive Coronary Angiography
Sponsor:   University of Edinburgh
Not yet recruiting - verified March 2016

ENdothelial Healing Assessment With Novel Coronary tEchnology

Condition:   Coronary Artery Disease
Interventions:   Device: SYNERGY stent;   Device: BVS ABSORB scaffold
Sponsors:   University of Malaya;   Boston Scientific Corporation;   Kurume University
Active, not recruiting - verified May 2016

Positive Psychology for ACS Patients: a Factorial Design Study

Condition:   Acute Coronary Syndrome
Interventions:   Other: Positive Psychology (PP);   Other: Motivational Interviewing (MI)
Sponsors:   Massachusetts General Hospital;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

CT COMPARE: CT COronary Angiography to Measure PlAque REduction

Condition:   Cardiovascular Disease
Interventions:   Drug: Rosuvastatin;   Drug: Atorvastatin
Sponsor:   National Institutes of Health Clinical Center (CC)
Recruiting - verified May 2016

High Intensity Interval Training in UK Cardiac Rehabilitation Programmes

Condition:   Coronary Disease
Intervention:   Other: High intensity interval training
Sponsors:   University Hospitals Coventry and Warwickshire NHS Trust;   Cardiff Metropolitan University;   City Health Care Partnership CIC (Hull);   University of Hull;   Aneurin Bevan University Heath Board;   Atrium Health, Coventry;   University of Bangor;   University of Warwick
Active, not recruiting - verified May 2016

Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibe

Condition:   Hypercholesterolemia
Intervention:   Drug: Rosuvastatin and Ezetimibe morning or evening administration
Sponsor:   Collegium Medicum w Bydgoszczy
Recruiting - verified May 2016

Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases

Conditions:   Diabetes Mellitus, Type 2;   Metabolic Syndrome X;   Hypertension;   Cardiovascular Diseases;   Stroke
Intervention:   Other: Fructose-containing Sugars
Sponsors:   University of Toronto;   Canadian Institutes of Health Research (CIHR);   The Physicians' Services Incorporated Foundation;   Canadian Diabetes Association (CDA)
Active, not recruiting - verified May 2016

Mindfulness & Stress Management Study for Cardiac Patients

Conditions:   Heart Diseases;   Heart Failure;   Myocardial Infarction;   Chronic Stable Angina;   Coronary Artery Bypass;   Angioplasty
Intervention:   Behavioral: Mindfulness-Based Stress Reduction (MBSR).
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Fairview Health Services
Recruiting - verified May 2016

SOP's for CKD-MBD-Biomarkers

Condition:   Chronic Kidney Diseases
Intervention:   Other: blood withdrawal
Sponsor:   RWTH Aachen University
Recruiting - verified February 2016

Percutaneous Coronary Intervention With the Angiolite Drug-eluting Stent: an Optical Cohenrece Tomography Study

Condition:   Coronary Heart Disease
Intervention:   Device: Angiolite stent
Sponsors:   Josep Rodes-Cabau;   iVascular
Recruiting - verified May 2016

The Impact of Text Messaging on Medication Adherence and Exercise Regimen Among Post-myocardial Infarction Patients

Condition:   Myocardial Infarction
Interventions:   Behavioral: Text message reminder for medication adherence;   Behavioral: Text message reminder for exercise regimen
Sponsors:   Brigham and Women's Hospital;   University of Waterloo
Completed - verified May 2016

Impact of Morphine Treatment on Platelet Inhibition in Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Morphinhydrochloricum;   Drug: Metoclopramide;   Drug: Ticagrelor;   Drug: Isotonic sodium chloride
Sponsor:   University of Luebeck
Recruiting - verified May 2016

Coronary Bifurcation Lesions Treated With Biguard Stent System

Condition:   Coronary Artery Disease
Interventions:   Device: Biguard sirolimus-eluting bifurcation stent system;   Device: Sirolimus-eluting stent system
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Active, not recruiting - verified May 2016

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified May 2016

Non-invasive Liver Screening for Risk Assessment for Coronary Heart Disease

Conditions:   Coronary Disease;   Non-alcoholic Fatty Liver Disease;   Elasticity Imaging Techniques
Interventions:   Device: Fibro Scan;   Genetic: PNPLA3
Sponsors:   University of Leipzig;   Universitätsklinikum Leipzig
Recruiting - verified May 2016

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

Conditions:   Secondary Prevention;   Stroke;   Ischemic Heart Disease;   Coronary Heart Disease
Interventions:   Drug: Acetylsalicylic Acid (Asprin, BAYE4465);   Drug: Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
Sponsor:   Bayer
Recruiting - verified May 2016

An Investigation to Evaluate an Over-The-Wire FFR Infusion Microcatheter (HYPEREM™IC) for Measuring Fractional Flow Reserve (FFR)

Condition:   Coronary Artery Disease
Intervention:   Device: FFR Infusion Microcatheter and standard intra-venous (IV) infusion
Sponsor:   Diasolve Ltd
Recruiting - verified May 2016

Ivabradine and Post-revascularisation Microcirculatory Dysfunction

Conditions:   Coronary Artery Disease;   Angina
Intervention:   Drug: Ivabradine
Sponsor:   Liverpool Heart and Chest Hospital NHS Foundation Trust
Suspended - verified May 2016

Comparison of a CrossBoss First Versus Standard Wire Escalation Strategy for Crossing Coronary Chronic Total Occlusion: the "CrossBoss First" Trial

Conditions:   Arteriosclerosis;   Coronary Artery Disease;   Myocardial Ischemia;   Coronary Disease
Interventions:   Procedure: CrossBoss Catheter;   Procedure: Antegrade Wire Escalation Strategy
Sponsors:   North Texas Veterans Healthcare System;   Henry Ford Hospital;   Massachusetts General Hospital;   North Central Heart-Avera Sacred Heart Hospital;   Saint Lukes Hospital Mid America Heart Institute;   Missouri Heart Center;   University of Washington
Enrolling by invitation - verified May 2016

Association Between Mitochondrial DNA Content and Risk of Coronary Heart Disease

Condition:   Coronary Heart Disease
Intervention:  
Sponsor:   Fourth Military Medical University
Completed - verified May 2016

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity

Conditions:   Posttraumatic Stress Disorder;   Depression;   Alcohol-Related Disorders;   Suicidal Ideation;   Substance-Related Disorders;   Mild Cognitive Impairment;   Quality of Life;   Pain;   Wounds and Injury;   Brain Injuries;   Chronic Disease
Interventions:   Behavioral: Motivational Interviewing;   Behavioral: Cognitive Behavioral Therapy Elements;   Behavioral: Care Management;   Drug: Fluoxetine;   Drug: Fluvoxamine;   Drug: Paroxetine;   Drug: Setraline;   Drug: Citalopram;   Drug: Venlafaxine;   Drug: Duloxetine;   Drug: Mirtazapine;   Drug: Diphenhydramine;   Drug: Trazodone;   Drug: Prazosin
Sponsors:   University of Washington;   National Institutes of Health (NIH)
Recruiting - verified May 2016

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified May 2016

FAST Feasibility Study

Condition:   Coronary Artery Disease
Intervention:   Device: Boston Scientific Fully Absorbable Scaffold
Sponsor:   Boston Scientific Corporation
Recruiting - verified May 2016

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Recruiting - verified May 2016

Prevention of Contrast Induced Nephropathy in Patients With Advanced Renal Dysfunction Undergoing Coronary Interventions

Conditions:   Kidney Disease, Chronic;   Ischemic Heart Disease
Intervention:   Procedure: Percutaneous coronary intervention
Sponsor:   Meir Medical Center
Recruiting - verified May 2016

Stress Ulcer Prophylaxis in the Intensive Care Unit

Conditions:   Gastrointestinal Bleeding;   Stress Ulcers
Interventions:   Drug: Pantoprazole;   Other: Saline (0.9%)
Sponsors:   Dr. Morten Hylander Møller;   Rigshospitalet, Denmark;   Copenhagen Trial Unit, Center for Clinical Intervention Research
Recruiting - verified May 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified May 2016

AVERT Plus Post-Market Registry

Condition:   Coronary Artery Disease
Intervention:   Device: AVERT Plus System
Sponsor:   Osprey Medical, Inc
Terminated - verified May 2015

The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome

Conditions:   Depression;   Acute Coronary Syndrome
Interventions:   Drug: Melatonin (N-acetyl-5-methoxytryptamine);   Drug: Placebo
Sponsors:   Roskilde County Hospital;   Psychiatric Research Unit, Region Zealand, Denmark;   University of Copenhagen;   Pharma Nord
Recruiting - verified May 2016

Effects of Tart Cherry and Aroniaberry Supplementation on Endothelial Function and Cardiovascular Measures in Healthy Older Adults: Interactions With Genotype and Proteome

Conditions:   Cardiovascular Disease;   Coronary Heart Disease;   Aging
Intervention:  
Sponsor:   National Institute of Nursing Research (NINR)
Recruiting - verified May 2016

A Study to Evaluate the Effects of Azilsartan on Coronary Artery Plaque in Essential Hypertensive Patients With Stable Angina and Dyslipidemia.

Condition:   Essential Hypertension With Stable Angina and Dyslipidemia
Intervention:   Drug: Azilsartan
Sponsor:   Takeda
Withdrawn - verified May 2016

Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Procedure: Computed tomography angiography (cardiac CT);   Procedure: Invasive coronary angiography (ICA)
Sponsor:   Charite University, Berlin, Germany
Recruiting - verified May 2016

Eplerenone in Heart Failure Treatment

Conditions:   Heart Failure;   Acute Myocardial Infarction;   Hypertension
Intervention:  
Sponsor:   Elpen Pharmaceutical Co. Inc.
Completed - verified May 2016

BIO monitorinG in Patients With Preserved Left ventricUlar Function AfteR Diagnosed Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Intervention:   Device: BioMonitor
Sponsor:   Biotronik SE & Co. KG
Recruiting - verified May 2016

Ticagrelor Pharmacokinetics in NSTEMI

Condition:   Myocardial Infarction
Intervention:   Drug: Ticagrelor
Sponsors:   Karolinska University Hospital;   AstraZeneca
Completed - verified May 2016

Computed Tomography (CT) Coronary Angiogram Evaluation in Cancer Patients Having CT Thorax, Abdomen and Pelvis

Condition:   Coronary Stenosis
Intervention:   Radiation: CT TAP Scan
Sponsor:   Plymouth Hospitals NHS Trust
Completed - verified May 2016

A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction

Conditions:   Heart Attack;   NSTEMI
Interventions:   Biological: AMI MultiStem cells;   Other: Sham
Sponsors:   Athersys, Inc;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified May 2016

PLATINUM Diversity

Conditions:   Atherosclerosis;   Coronary Artery Disease
Intervention:   Device: Percutaneous coronary intervention (Promus PREMIER)
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified May 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2016

Exploring the Mechanism of the Plaque Rupture in Acute Myocardial Infarction

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction;   Plaque, Atherosclerotic;   Rupture, Spontaneous
Intervention:  
Sponsors:   Seoul National University Hospital;   HeartFlow, Inc.;   Kyoto University, Graduate School of Medicine;   Inje University;   Keimyung University Dongsan Medical Center;   Ulsan University Hospital;   Wakayama Medical University;   Aarhus University Hospital
Active, not recruiting - verified May 2016

Intravascular Ultrasound Guided Drug Eluting Stent Implantation in "All-comers" Coronary Lesions

Condition:   Coronary Artery Disease
Interventions:   Procedure: Angiography;   Procedure: IVUS;   Procedure: DES implantation
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified May 2016

Safety of "Ticagrelor+ Warfarin"in Comparison With "Clopidogrel+Aspirin+Warfarin"

Conditions:   Atrial Fibrillation;   Coronary Artery Disease
Interventions:   Drug: Ticagrelor+Warfarin;   Drug: Clopidogrel+Aspirin+Warfarin
Sponsors:   Genshan Ma;   Zhongda Hospital
Recruiting - verified May 2016

Computed TomogRaphic Evaluation of Atherosclerotic DEtermiNants of Myocardial IsChEmia

Condition:   Myocardial Ischemia
Intervention:  
Sponsors:   Weill Medical College of Cornell University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Dual Energy CT for Ischemia Determination Compared to "Gold Standard" Non-Invasive and Invasive Techniques

Condition:   Ischemia
Intervention:   Procedure: CT and stress test
Sponsors:   Weill Medical College of Cornell University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified May 2016

Comparison Between Moderate-high Interval Exercise and Moderate Continuous Exercise in an Advanced Cardiac Rehabilitation Program

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Interventions:   Other: Interval exercise training;   Other: Continuous exercise training
Sponsor:   Assaf-Harofeh Medical Center
Completed - verified May 2016

Comparison of Agent™ and SeQuent® Please Paclitaxel Coated Balloon Catheters in Coronary In-stent Restenosis (AGENT-ISR)

Conditions:   Coronary Artery Disease;   Coronary Restenosis;   Coronary Atherosclerosis;   Coronary Arteriosclerosis
Interventions:   Device: Agent Paclitaxel-coated balloon;   Device: SeQuent® Please Paclitaxel-coated Balloon
Sponsor:   Hemoteq AG
Active, not recruiting - verified May 2016

TEAMS (Troponin Elevation After Major Surgery) Study

Conditions:   Perioperative Myocardial Infarction;   Disability
Intervention:  
Sponsor:   University Health Network, Toronto
Active, not recruiting - verified November 2015

Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   University of Texas Southwestern Medical Center
Recruiting - verified May 2016

Antiplatelet Therapy Following Stent Implantation

Conditions:   Acute Myocardial Infarction;   Coronary Syndrome;   Angina, Unstable
Intervention:  
Sponsor:   Elpen Pharmaceutical Co. Inc.
Completed - verified May 2016

Developing and Testing a Personalized Evidence-based Shared Decision-making Tool for Stent Selection

Condition:   Heart Diseases
Intervention:  
Sponsors:   University of Missouri, Kansas City;   Patient-Centered Outcomes Research Institute
Enrolling by invitation - verified May 2016

HEART Pathway Implementation

Conditions:   Chest Pain;   Acute Coronary Syndrome;   Chest Pain Atypical Syndrome;   Chest Pain Rule Out Myocardial Infarction
Intervention:  
Sponsors:   Wake Forest Baptist Health;   Association of American Medical Colleges;   Donaghue Medical Research Foundation
Active, not recruiting - verified May 2016

Multicenter Comparison of Early and Late Vascular Responses to Everolimus-eluting Cobalt-CHromium Stent and Platelet AggregatioN studIeS for TreatMent of Acute Myocardial InfarctionTreatment of ST-elevation Acute Myocardial Infarction

Condition:   Coronary Artery Disease
Intervention:   Device: cobalt-chromium everolimus-eluting stent (CoCr-EES)
Sponsor:   Iwate Medical University
Active, not recruiting - verified May 2016

Effects of Ranolazine and Exercise on Daily Physical Activity Trial

Condition:   Chronic Stable Angina
Interventions:   Drug: Ranolazine;   Behavioral: Aerobic Exercise;   Drug: Placebo
Sponsors:   Duke University;   Gilead Sciences
Recruiting - verified May 2016

Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Recruiting - verified May 2016

Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease

Conditions:   Kawasaki Disease;   Coronary Aneurysm
Interventions:   Drug: Doxycycline;   Drug: Standard care
Sponsor:   Hawaii Pacific Health
Recruiting - verified May 2016

Chronic Remote Ischemic Conditioning to Modify Post-MI Remodeling

Condition:   Myocardial Infarction
Intervention:   Device: Auto Remote Ischemic Conditioning (AutoRIC) device
Sponsors:   The Hospital for Sick Children;   University Health Network, Toronto;   Sunnybrook Health Sciences Centre;   St. Michael's Hospital, Toronto
Withdrawn - verified May 2016

Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aortic Dissection.

Conditions:   Turner Syndrome;   Aortic Aneurysm;   Ischemic Heart Disease;   Hypertension;   Congenital Heart Defect
Intervention:  
Sponsor:   University of Aarhus
Active, not recruiting - verified June 2015

X-chromosome Inactivation, Epigenetics and the Transcriptome

Conditions:   Turner Syndrome;   Klinefelter Syndrome;   Triple X Syndrome;   47 XYY Syndrome;   Aortic Aneurysm
Intervention:  
Sponsors:   University of Aarhus;   Lundbeck Foundation;   The Korning Foundation Denmark;   AP Moeller Foundation
Completed - verified June 2015

Acute Versus Subacute Angioplasty in Patients With NON-ST-Elevation Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Procedure: Group I: Primary PCI
Sponsor:   Aarhus University Hospital Skejby
Terminated - verified May 2016

Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease

Conditions:   Overweight;   Obesity;   Dyslipidemia;   Hyperlipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Gout;   Hypertension;   Metabolic Syndrome;   Coronary Heart Disease;   Cardiovascular Disease
Intervention:  
Sponsors:   John Sievenpiper;   Calorie Control Council;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2016

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified May 2016

Cardiovascular Inflammation Reduction Trial

Condition:   Cardiovascular Disease
Interventions:   Drug: Methotrexate;   Drug: Placebo
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Primary Reperfusion Secondary Stenting Trial

Condition:   ST-elevation Myocardial Infarction
Intervention:   Procedure: Percutaneous coronary intervention
Sponsor:   Montreal Heart Institute
Recruiting - verified May 2016

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   New York University School of Medicine;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University
Recruiting - verified May 2016

Prevention of Serious Adverse Events Following Angiography

Conditions:   Acute Renal Failure;   Kidney Disease;   Coronary Artery Disease
Interventions:   Drug: IV isotonic saline;   Drug: IV isotonic bicarbonate;   Drug: N-acetylcysteine;   Drug: Placebo
Sponsors:   VA Office of Research and Development;   The George Institute
Recruiting - verified May 2016

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Recruiting - verified May 2016

The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry

Conditions:   Spontaneous Coronary Artery Dissection;   SCAD
Intervention:  
Sponsor:   Mayo Clinic
Recruiting - verified May 2016

Early Thienopyridine Treatment to Improve Primary Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction

Conditions:   Myocardial Infarction;   STEMI
Interventions:   Drug: prasugrel;   Drug: Clopidogrel
Sponsors:   Stiftung Institut fuer Herzinfarktforschung;   Daiichi Sankyo Inc.
Completed - verified May 2016

International Survey of Acute Coronary Syndromes in Transitional Countries

Conditions:   Acute Coronary Syndrome;   Unstable Angina Pectoris;   Myocardial Infarction;   Coronary Disease
Intervention:  
Sponsor:   University of Bologna
Recruiting - verified May 2016

MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use

Conditions:   Acne Vulgaris;   Allergic Rhinitis;   Anxiety;   Asthma;   Back Pain;   Prostatic Hyperplasia;   Bursitis;   Chronic Obstructive Pulmonary Disease;   Cough;   Coronary Artery Disease;   Depression;   Diabetes Mellitus;   Diarrhea;   Gastroesophageal Reflux;   Fibromyalgia;   Headache;   HIV Infections;   Hypothyroidism;   Hyperlipidemia;   Hypertension;   Influenza;   Sleep Initiation and Maintenance Disorders;   Irritable Bowel Syndrome;   Knee Pain;   Migraine Disorders;   Obesity;   Obstructive Sleep Apnea;   Osteoarthritis;   Senile Osteoporosis;   Colonoscopy;   Mammography;   Shoulder Pain;   Sinusitis;   Smoking Cessation;   Tobacco Use Cessation;   Menopause;   Urinary Incontinence;   Urinary Tract Infection;   Vaccination;   Vaginitis;   Vertigo
Intervention:   Other: health information prescription
Sponsors:   University of Missouri-Columbia;   National Library of Medicine (NLM)
Completed - verified March 2011

Strict or Liberal Insulin Protocol Following Coronary Artery Bypass Graft (CABG) Surgery

Conditions:   Blood Glucose;   Coronary Artery Bypass;   Insulin;   Coronary Disease
Intervention:   Other: LIBERAL
Sponsor:   Inova Health Care Services
Active, not recruiting - verified May 2016

Individualized Comprehensive Atherosclerosis Risk-reduction Evaluation Program

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Piedmont Healthcare;   Abbott
Active, not recruiting - verified May 2016

Premature Coronary Artery Disease (CAD) in Severe Psoriasis

Conditions:   Psoriasis;   Coronary Artery Disease
Intervention:   Procedure: CCTA Scan (Coronary CT Angiogram)
Sponsor:   University of Michigan
Active, not recruiting - verified May 2016

Trial of Drug Eluting Stent Versus Bare Metal Stent to Treat Coronary Artery Stenosis

Conditions:   Coronary Atherosclerosis;   Angina Pectoris;   Myocardial Infarction
Interventions:   Device: Percutaneous coronary intervention (PCI);   Device: Percutaneous coronary intervention (PCI)
Sponsors:   University of Tromso;   The Research Council of Norway;   The Royal Norwegian Ministry of Health;   Norwegian Council on Cardiovascular diseases
Active, not recruiting - verified May 2016

Effect of Remote Ischemic Preconditioning in Patient Undergoing Cardiac Bypass Surgery

Condition:   Coronary Heart Disease
Interventions:   Procedure: Remote ischemic preconditioning;   Procedure: Placebo
Sponsor:   University College London Hospitals
Recruiting - verified May 2016

Dehydroepiandrosterone (DHEA) in Systemic Lupus Erythematosus (SLE) for Coronary Artery Disease (CAD) Prevention

Condition:   Systemic Lupus Erythematosus
Intervention:   Drug: Dehydroepiandrosterone (DHEA)
Sponsors:   University of Michigan;   Arthritis Foundation
Completed - verified May 2016

Safety of SCH 530348 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention (Study P03573)

Conditions:   Arterial Obstructive Diseases;   Coronary Disease
Intervention:   Drug: SCH 530348
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified May 2016

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016