Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Evaluation of Plasma Non-coding RNAs as Biomarkers in Coronary Heart Disease

Condition:   Coronary Disease
Intervention:   Other: No intervention
Sponsor:   Tongji Hospital
Not yet recruiting - verified April 2016

Home-based Cardiovascular Rehabilitation, Maintenance Phase, in Subjects With Coronary Artery Disease

Conditions:   Coronary Heart Disease;   Acute Myocardial Infarction: Rehabilitation Phase
Interventions:   Procedure: Cardiovascular rehabilitation program using Kinect of Xbox;   Procedure: Cardiovascular rehabilitation program using paper manual;   Other: Educational component
Sponsor:   Ágata Sofia da Silva Vieira
Completed - verified April 2016

Platelet Inhibition of Ticagrelor Versus Clopidogrel in Type 2 Diabetic Patients After Elective Percutaneous Coronary Intervention

Conditions:   Coronary Artery Disease;   Diabetes Mellitus, Type 2
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel;   Drug: Aspirin
Sponsor:   Peking Union Medical College Hospital
Not yet recruiting - verified April 2016

Clinical Observation of Coronary Arterial Microcirculation Dysfunction in Diabetic Patients With Non- Obstructive Coronary Artery Disease

Conditions:   Complications of Diabetes Mellitus;   Coronary Artery Disease
Intervention:  
Sponsor:   Shaanxi Provincial People's Hospital
Recruiting - verified April 2016

A Comparative Evaluation of the Extent of Neointima Formation at 1 Month and 2 Months After Implantation Using OCT

Conditions:   Coronary Artery Disease;   Stable Angina Pectoris;   Unstable Angina Pectoris
Interventions:   Device: BuMA Supreme™ stent;   Device: Xience V/Prime stent
Sponsor:   Sino Medical Sciences Technology Inc.
Not yet recruiting - verified April 2016

Appropriateness of Coronary Angioplasty in PAtients With isCHEmic Heart Disease

Conditions:   Non ST Elevation Acute Coronary Syndromes;   Stable Coronary Syndromes;   NSTEMI;   Unstable Angina
Intervention:  
Sponsors:   Italian Society of Invasive Cardiology;   IRCCS Policlinico S. Matteo
Recruiting - verified April 2016

Impact of Allo- and Autoantibodies on Chronic Cardiac Allograft Function

Conditions:   Pediatric Heart Transplantation;   Pediatric Heart Transplant Recipients
Intervention:  
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Clinical Trials in Organ Transplantation in Children
Recruiting - verified April 2016

Postapproval Trial On Carotid Stenting in Patients With High Risk Vs Standard Risk for Open Carotid Endarterectomy(REAL)

Condition:   Carotid Artery Diseases
Intervention:  
Sponsor:   Joaquin de Haro, M.D.
Completed - verified April 2016

Influence of Myocardial Shortening on Coronary Tortuosity

Conditions:   Coronary Artery Vessels;   Coronary Artery Disease
Intervention:   Other: No intervention. Observational study
Sponsor:   Oregon Health and Science University
Recruiting - verified April 2016

Positive Psychology for ACS Patients: a Factorial Design Study

Condition:   Acute Coronary Syndrome
Interventions:   Other: Positive Psychology (PP);   Other: Motivational Interviewing (MI)
Sponsors:   Massachusetts General Hospital;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2016

Brazilian Registry of Acute SItuations in Emergency Department - BRASIED Registry

Conditions:   Acute Coronary Syndromes;   Heart Failure;   Pulmonary Edema;   Aortic Aneurysm, Familial Thoracic 1;   Chest Pain;   Pulmonary Embolism;   Syncope
Intervention:   Other: no intervention
Sponsor:   University of Sao Paulo General Hospital
Recruiting - verified April 2016

HELIox CardiOPlegia Trial During Cardiac surgERy

Condition:   C.Surgical Procedure; Cardiac
Interventions:   Other: Heliox;   Other: Standard of care
Sponsor:   David Mazer
Recruiting - verified April 2016

Pilot - Peri-operative Beta Blockade

Conditions:   Adrenergic Beta-Receptor Blockader;   Troponin Levels;   Cardiomyopathy, Post-surgical
Intervention:   Drug: metoprolol
Sponsor:   Washington University School of Medicine
Recruiting - verified April 2016

Sex and Gender Differences in Ischemic Heart Disease - Endocrine Vascular Disease Approach

Condition:   Myocardial Ischemia
Intervention:   Procedure: percutaneous coronary intervention
Sponsors:   University of Roma La Sapienza;   Ministry of Education, Universities and Research, Italy
Recruiting - verified April 2016

Does Frailty Help Predict Postoperative Outcomes in Cardiac Surgery?

Conditions:   Coronary Heart Disease;   Heart Valve Diseases
Intervention:  
Sponsor:   King's College Hospital NHS Trust
Enrolling by invitation - verified April 2016

Early or Delayed Revascularization for Intermediate and High-risk Non ST-elevation Acute Coronary Syndromes?

Condition:   Acute Coronary Syndrome
Intervention:   Procedure: Percutaneous coronary intervention for revascularization
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified April 2016

The Role of Values, Acceptance, and Mindfulness Strategies in Long Term Weight Management

Condition:   Obesity
Intervention:   Behavioral: Acceptance and Commitment Therapy
Sponsor:   Nova Scotia Health Authority
Not yet recruiting - verified April 2016

Effects of Induced Moderate HYPOthermia on Mortality in Cardiogenic Shock Patients Rescued by Veno-arterial ExtraCorporeal Membrane Oxygenation (ECMO)

Condition:   Cardiogenic Shock
Intervention:   Other: moderate hypothermia
Sponsor:   Central Hospital, Nancy, France
Not yet recruiting - verified April 2016

Thrombus Aspiration in Acute ST-elevation Myocardial Infarction

Condition:   Acute ST-elevation Myocardial Infarction
Intervention:  
Sponsor:   Oslo University Hospital
Recruiting - verified April 2016

Evaluation to Assess Cognitive Training for the Prevention of Post-operative Cognitive Decline

Condition:   Cognitive Dysfunction
Intervention:   Behavioral: Cognitive training program RehaCom®
Sponsor:   Charite University, Berlin, Germany
Not yet recruiting - verified April 2016

Safety and Feasibility of Intracoronary Hypothermia in Acute Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Other: intracoronary infusion with saline on 22 and 4°C
Sponsor:   Catharina Ziekenhuis Eindhoven
Not yet recruiting - verified April 2016

Gradual Reperfusion and Microvascular Integrity and Myocardial Oedema Patients Undergoing Primary PCI

Condition:   ST-elevation Acute Myocardial Infarction
Interventions:   Device: deferred coronary stenting;   Device: immediate stenting
Sponsor:   Istanbul University
Recruiting - verified April 2016

Researching the Diagnosis and Treatment of Targeting Nano microRNA in the Patients of Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Septic Shock
Intervention:  
Sponsor:   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Active, not recruiting - verified April 2016

Simultaneous Assessment of FFR and SPECT

Condition:   Coronary Artery Disease
Intervention:   Radiation: SPECT imaging
Sponsors:   University of Pittsburgh;   Astellas Pharma US, Inc.
Not yet recruiting - verified April 2016

ShenFu Injection for Myocardial Protection in Patients With Acute ST Segment Elevation Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Drug: Shenfu Injection;   Drug: 5% Glucose Injection
Sponsors:   Beijing Anzhen Hospital;   China Resources Sanjiu Medical & Pharmaceutical Co., Ltd.
Recruiting - verified April 2016

Shockwave Coronary Rx Lithoplasty ® Study

Condition:   Coronary Artery Disease
Intervention:   Device: Shockwave Medical Coronary Rx Lithoplasty System
Sponsor:   Shockwave Medical, Inc.
Recruiting - verified April 2016

Randomized Trial of COBRA PzF Stenting to Reduce Duration of Triple Therapy

Conditions:   Angina, Stable;   Angina, Unstable;   Anticoagulants
Interventions:   Device: COBRA PzF;   Device: DES
Sponsor:   CeloNova BioSciences, Inc.
Recruiting - verified April 2016

Old Blood and Postoperative Complications

Conditions:   Orthopedics;   Postoperative Complications;   Red Blood Cells
Interventions:   Procedure: Old red blood cells transfusion;   Procedure: New red blood cells transfusion
Sponsor:   Seoul National University Hospital
Recruiting - verified April 2016

Treadmill CV Safety Study

Condition:   Stable Angina
Interventions:   Drug: AMG 334;   Drug: Placebo
Sponsor:   Amgen
Recruiting - verified April 2016

More Intensive Cardiac Rehabilitation Programs in Less Time

Condition:   Acute Coronary Syndrome
Intervention:   Other: Intensive cardiac rehabilitation program in less time
Sponsor:   Almudena Castro Conde
Recruiting - verified April 2016

Boston Scientific COMET Wire Validation Study

Condition:   Stable Angina
Interventions:   Device: Boston Scientific Pressure Wire;   Device: Validation of Boston Scientific pressure wire
Sponsors:   University Hospital Southampton NHS Foundation Trust.;   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Boston Scientific Corporation
Recruiting - verified April 2016

Pilot Study of the Fantom Bioresorbable Scaffold (FANTOM I)

Condition:   Coronary Artery Disease
Intervention:   Device: Fantom Scaffold
Sponsor:   REVA Medical, Inc.
Active, not recruiting - verified April 2016

COOL AMI EU Pilot Trial to Assess Cooling as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Device: Cooling + PCI;   Device: PCI only
Sponsor:   ZOLL Circulation, Inc., USA
Recruiting - verified April 2016

Aspirin Twice a Day in Patients With Diabetes and Acute Coronary Syndrome

Conditions:   Diabetes Mellitus;   Acute Coronary Syndrome;   Coronary Artery Disease
Interventions:   Drug: Novel strategy Aspirin;   Drug: Conventional strategy Aspirin
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Bayer
Not yet recruiting - verified April 2016

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Recruiting - verified April 2016

Stress Ulcer Prophylaxis in the Intensive Care Unit

Conditions:   Gastrointestinal Bleeding;   Stress Ulcers
Interventions:   Drug: Pantoprazole;   Other: Saline (0.9%)
Sponsors:   Dr. Morten Hylander Møller;   Rigshospitalet, Denmark;   Copenhagen Trial Unit, Center for Clinical Intervention Research
Recruiting - verified April 2016

Vortioxetine in Patients With Major Depressive Disorder and Coronary Artery Disease

Conditions:   Major Depressive Disorder;   Coronary Artery Disease
Intervention:   Drug: Vortioxetine
Sponsors:   Thomas Jefferson University;   Takeda
Recruiting - verified April 2016

Verapamil vs Heparin in Transradial Procedures

Condition:   Heart Disease, Ischemic
Interventions:   Drug: Heparin;   Drug: Verapamil
Sponsor:   University Hospital of Ferrara
Recruiting - verified April 2016

Feasibility and Effectiveness of Remote Virtual Reality-Based Cardiac Rehabilitation

Condition:   Myocardial Infarction
Intervention:   Behavioral: MedBIKE
Sponsors:   University of Alberta;   Alberta Health Services
Not yet recruiting - verified April 2016

Women's Health Initiative Strong and Healthy Study

Conditions:   Myocardial Infarction;   Stroke;   Cardiovascular Mortality;   Hip Fractures;   Falls;   Mortality;   Venous Thromboembolic Event;   Peripheral Artery Disease
Intervention:   Behavioral: Physical Activity
Sponsors:   Fred Hutchinson Cancer Research Center;   University of California, San Diego;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified April 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified April 2016

Epigenetic Reprogramming of Monocytes in Patients With Coronary Atherosclerosis

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Radboud University;   Canisius-Wilhelmina Hospital
Completed - verified April 2016

Brilinta Taiwan Post Approval Safety Study

Condition:   Non ST-elevation Myocardial Infarction
Intervention:   Drug: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Sponsor:   AstraZeneca
Active, not recruiting - verified April 2016

The Asahi Intecc PTCA Chronic Total Occlusion Study

Conditions:   Coronary Artery Disease;   Coronary Artery Chronic Total Occlusion
Intervention:   Device: Revascularization of Coronary Artery Chronic Total Occlusion (Corsair, Gaia, Asahi Guide Wires)
Sponsors:   Asahi Intecc USA Inc;   Medpace, Inc.
Completed - verified April 2016

CD0104 VEST II Post Marketing Surveillance Study

Condition:   Coronary Artery Bypass Surgery
Intervention:   Device: VEST
Sponsor:   Vascular Graft Solutions Ltd.
Completed - verified October 2015

Mechanistic Study of Bleeding Risk in Coronary Patients With Cerebrovascular Disease

Conditions:   Coronary Artery Disease;   Cerebral Stroke;   TIA (Transient Ischemic Attack)
Intervention:  
Sponsors:   University of Sao Paulo General Hospital;   Fundação de Amparo à Pesquisa do Estado de São Paulo
Completed - verified June 2014

Bivalirudin Infusion for Ventricular Infarction Limitation

Condition:   Acute Myocardial Infarction
Interventions:   Procedure: primary PCI;   Drug: Bivalirudin
Sponsor:   The Medicines Company
Active, not recruiting - verified April 2016

Tako-Tsubo Cardiomyopathy and Cardiac Syndrome X: New Insights Into the Pathophysiology

Conditions:   Syndrome X;   Takotsubo Cardiomyopathy
Intervention:   Other: BaroReflex Sensitivity, endothelial function measurement
Sponsor:   Ospedale San Giovanni Bellinzona
Completed - verified April 2016

Mechanisms of Social Inequalities in Post-hospitalization Rehabilitation in Patients With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Nordsjaellands Hospital
Active, not recruiting - verified April 2016

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified April 2016

Trajectory of Positive Psychological States in Patients With ACS

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   Massachusetts General Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2016

Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Condition:   Hypercholesterolemia
Intervention:   Biological: Evolocumab
Sponsor:   Amgen
Enrolling by invitation - verified April 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified April 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2016

A Registration Study for Dyslipidemia

Condition:   Atherosclerotic Vascular Diseases
Intervention:  
Sponsor:   National Taiwan University Hospital
Recruiting - verified April 2016

Effects of Low Dose Aspirin Pre-treatment on Platelet Activation Undergoing Off-pump Coronary Artery Bypass Surgery

Condition:   Coronary Artery Disease
Interventions:   Drug: aspirin continuation;   Drug: aspirin discontinuation
Sponsor:   Seoul National University Hospital
Completed - verified August 2014

Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial

Condition:   Coronary Disease
Interventions:   Device: computed tomography perfusion guided treatment;   Device: Fractional flow reserve guided treatment
Sponsor:   Young-Hak Kim, MD, PhD
Recruiting - verified April 2016

Exercise Behavior Among Young Adults Study

Condition:   Physical Activity
Interventions:   Other: Exercise info;   Other: Implementation intentions;   Other: Industriousness;   Device: pedometer
Sponsor:   Wayne State University
Active, not recruiting - verified April 2016

Telehealth Self-Management Program in Older Adults Living With Heart Failure in Health Disparity Communities

Condition:   Chronic Heart Failure
Interventions:   Device: Telehealth Self Management (TSM);   Other: Standard of Care
Sponsor:   Northwell Health
Recruiting - verified April 2016

Prospective, Single-arm, Multi Centre Observations Ultimaster Des Registry

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Terumo Europe N.V.
Recruiting - verified April 2016

The North Sea Race Endurance Exercise Study

Condition:   Healthy
Intervention:  
Sponsors:   Helse Stavanger HF;   Nordsjørittet;   Abbott
Active, not recruiting - verified April 2016

DLBS1033 for Acute NSTEMI Without Early Coronary Revascularization

Condition:   Acute Non-ST Elevation Myocardial Infarction
Interventions:   Drug: DLBS1033;   Drug: Placebo
Sponsor:   Dexa Medica Group
Withdrawn - verified April 2016

Outcomes of Angiotensin Converting Enzyme Inhibitor Management Strategies Prior to Coronary Artery Bypass

Condition:   Coronary Artery Disease
Interventions:   Drug: ACE/ARB continuation;   Drug: ACE/ARB withdrawal
Sponsor:   University of Alberta
Recruiting - verified April 2016

The Lipid-Rich Plaque Study

Conditions:   Coronary Artery Disease;   Atherosclerosis
Intervention:  
Sponsors:   InfraReDx;   Medstar Research Institute
Active, not recruiting - verified April 2016

Is Our Microbiome a Predictor of Cardiac Risk

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Mayo Clinic
Recruiting - verified April 2016

Study of the Vascular Effects of Serelaxin

Condition:   Coronary Artery Disease
Interventions:   Drug: Serelaxin;   Other: Placebo
Sponsor:   Novartis Pharmaceuticals
Recruiting - verified April 2016

COOL-AMI EU Case Series Clinical Study

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   ZOLL Circulation, Inc., USA
Recruiting - verified April 2016

Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Recruiting - verified April 2016

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified April 2016

Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention

Condition:   Acute ST Segment Elevation Myocardial Infarction
Interventions:   Drug: NAC;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified April 2016

The TRUST Study - Depression Substudy

Conditions:   Subclinical Hypothyroidism;   Depression
Interventions:   Drug: Levothyroxine;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   Leiden University Medical Center;   University of Bern
Recruiting - verified April 2016

Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Interventions:   Drug: N-acetyl cysteine;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified April 2016

Propofol Effects on Mitral Valve Annular Velocity

Conditions:   Valvular Heart Disease;   Coronary Artery Disease
Interventions:   Drug: Propofol 1.0mcg;   Drug: Propofol 2.0mcg;   Drug: Propofol 3.0mcg
Sponsor:   Konkuk University Medical Center
Completed - verified April 2016

Safety Study of PZ-128 in Subjects With Multiple Coronary Artery Disease Risk Factors

Conditions:   Vascular Disease;   Coronary Artery Disease Risk Factors Multiple
Intervention:   Drug: PZ-128
Sponsors:   Tufts Medical Center;   National Heart, Lung, and Blood Institute (NHLBI);   Sinai Hospital of Baltimore
Completed - verified April 2016

Comparison of the Angiographic Result of the Orsiro Hybrid Stent With Resolute Integrity Stent

Conditions:   Coronary Artery Disease;   Coronary Heart Disease;   Stable Angina;   Unstable Angina;   ST-segment Elevation Myocardial Infarction;   Non-ST-segment Elevation Myocardial Infarction
Interventions:   Device: Osiro Hybrid Drug-Eluting Stent;   Device: Resolute Integrity
Sponsors:   Seoul National University Bundang Hospital;   Jeju National University Hospital;   Chungbuk National University Hospital;   SMG-SNU Boramae Medical Center;   Korea University;   Inje University;   Kyung Hee University Hospital at Gangdong;   Inha University Hospital
Completed - verified April 2016

Effect of Ticagrelor on Endothelial Function

Conditions:   Coronary Artery Disease;   Endothelial Function
Interventions:   Drug: clopidogrel;   Drug: Ticagrelor
Sponsor:   Lawson Health Research Institute
Active, not recruiting - verified April 2016

Myocardial Perfusion Study to Detect Coronary Microvascular Abnormality in Diabetic Patients With Nonfatal Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:  
Sponsor:   State University of New York - Upstate Medical University
Recruiting - verified April 2016

Stentys Coronary Stent System Clinical Trial in Patients With Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Device: STENTYS self-apposing stent;   Device: VISION balloon-expandable stent
Sponsor:   Stentys
Active, not recruiting - verified November 2015

The Diagnosis and Treatment of Resistant Hypertension, the Prevalence and the Prognosis

Condition:   Hypertension, Resistant to Conventional Therapy
Intervention:  
Sponsors:   Chinese Academy of Medical Sciences, Fuwai Hospital;   Huazhong University of Science and Technology;   Shanghai Jiao Tong University School of Medicine
Active, not recruiting - verified April 2016

A Clinical Evaluation of ST Changes in a Group of Patients Having Ventricular Arrhythmias

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   St. Jude Medical
Completed - verified April 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified April 2016

Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery

Conditions:   Congenital Heart Disease;   Heart Valve Disease
Intervention:   Drug: simvastatin
Sponsor:   Sun Yat-sen University
Recruiting - verified April 2016

Effects of Vildagliptin/Metformin Combination on Markers of Atherosclerosis, Thrombosis, and Inflammation in Diabetics With Coronary Artery Disease

Conditions:   Type 2 Diabetes Mellitus;   Ischemic Heart Disease
Interventions:   Drug: Metformin plus vildagliptin;   Drug: Metformin only
Sponsor:   Sheba Medical Center
Completed - verified April 2016

Clinical Investigation for Safety and Efficacy Study of CELT ACD Arterial Closure Device

Conditions:   Cardiac Disease;   Coronary Artery Disease
Intervention:   Device: CELT ACD
Sponsor:   Vasorum Ltd
Completed - verified April 2016

Thrombus Aspiration in ThrOmbus Containing culpRiT Lesions in Non-ST-Elevation Myocardial Infarction (TATORT-NSTEMI)

Condition:   Non-ST-elevation Myocardial Infarction
Interventions:   Procedure: Thrombectomy;   Procedure: Standard percutaneous coronary intervention
Sponsor:   University of Leipzig
Active, not recruiting - verified April 2016

Age-Related Changes in Body Composition

Conditions:   Hypertension;   Atherosclerosis
Intervention:  
Sponsor:   National Institute on Aging (NIA)
Completed - verified November 2015

NBS10 (Also Known as AMR-001) Versus Placebo Post ST Segment Elevation Myocardial Infarction

Condition:   ST Segment Elevation Myocardial Infarction
Interventions:   Biological: NBS10;   Other: placebo
Sponsor:   Caladrius Biosciences, Inc.
Completed - verified April 2016

Clearance Of Mucus In Stents

Conditions:   Lung Neoplasms;   Respiratory Failure;   Pneumonia;   Acute Coronary Syndromes;   Unstable Angina;   Myocardial Infarction;   Cardiac Arrhythmia;   Thromboembolic Disease
Interventions:   Other: Normal Saline;   Other: Sodium Bicarbonate
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified April 2016

Investigate Effect on Mean IMT of Probucol And/or CilosTazol in Patients With Coronary Heart dIsease Taking HMGCoA Reductase Inhibitor Therapy

Condition:   Hyperlipidemias
Interventions:   Drug: HMGCoA reductase inhibitor;   Drug: HMGCoA reductase inhibitor + probucol;   Drug: HMGCA reductase inhibitor + probucol + cilostazol
Sponsors:   Seoul National University Hospital;   Korea Otsuka Pharmaceutical Co.,Ltd.
Active, not recruiting - verified April 2016

Prospective, Single Blind, Rand Controlled Study to Evaluate the Safety & Effectness of Tryton Side Branch Stent Used With DES Treatmt of de Novo Bifurcation Lesions in MB & SB in Native Coronaries

Conditions:   Coronary Atherosclerosis of Native Coronary Artery;   Bifurcation Lesions: de Novo Lesions of the Main and Side Branch of Native Coronary Artery
Interventions:   Device: Tryton Side Branch Stent with main branch DES;   Device: POBA
Sponsor:   Tryton Medical, Inc.
Active, not recruiting - verified April 2016

Evaluation of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: follow-up coronary angiography;   Procedure: Clinical follow-up
Sponsor:   Takeshi Morimoto
Active, not recruiting - verified April 2016

The Healthy Elderly Longevity Cohort

Condition:   Healthy
Intervention:  
Sponsor:   Scripps Translational Science Institute
Recruiting - verified April 2016

Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE)

Conditions:   Acute Coronary Syndrome;   Chest Pain
Intervention:  
Sponsor:   Kavitha Chinnaiyan
Active, not recruiting - verified April 2016

The Melatonin Adjunct in the Acute myocaRdial Infarction Treated With Angioplasty

Condition:   Acute Myocardial Infarction
Intervention:   Drug: melatonin
Sponsor:   Alberto Dominguez-Rodriguez, MD, PhD, FESC
Active, not recruiting - verified April 2016

Evaluation Using Computed Tomography Angiography (CTA) to Investigate and Detect Atherosclerotic Graft Disease (ELUCIDATE)

Conditions:   Arteriosclerosis of Coronary Artery Bypass Graft;   Coronary Artery Disease
Intervention:  
Sponsor:   William Beaumont Hospitals
Completed - verified April 2016

Intraaortic Balloon Pump in Cardiogenic Shock II

Conditions:   Myocardial Infarction;   Shock, Cardiogenic
Intervention:   Device: Intraaortic balloon pump
Sponsor:   University of Leipzig
Active, not recruiting - verified April 2016

ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

Conditions:   Cardiovascular Disease;   Coronary Artery Calcification
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified November 2015

hsCRP in Japan Statin Treatment Against Recurrent Stroke (J-STARS hsCRP)

Condition:   Ischemic Stroke
Intervention:   Drug: Statin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University;   Osaka University
Completed - verified April 2016

Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study)

Conditions:   Atherosclerosis;   Cardiovascular Disease;   Vascular Diseases
Intervention:  
Sponsor:   National Institute on Aging (NIA)
Active, not recruiting - verified March 2016

Japan Statin Treatment Against Recurrent Stroke (J-STARS)

Condition:   Ischemic Stroke
Intervention:   Drug: Pravastatin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University
Completed - verified March 2015

Estrogen, HDL, and Coronary Heart Disease in Women

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Heart Diseases;   Coronary Arteriosclerosis
Interventions:   Drug: Estrogens, Conjugated (USP);   Drug: Medroxyprogesterone 17-Acetate;   Drug: Placebo
Sponsors:   Tufts University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2016

Jackson Heart Study (JHS) of Cardiovascular Diseases in African Americans

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Atherosclerosis;   Coronary Disease;   Hypertension;   Cerebrovascular Disorders
Intervention:  
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Institute on Minority Health and Health Disparities (NIMHD)
Active, not recruiting - verified April 2016

Effects of Endotoxin in Normal Human Volunteers

Conditions:   Healthy;   Lung Disease;   Sepsis;   Septic Shock
Interventions:   Drug: Reference Endotoxin;   Drug: Inhaled Nitric Oxide
Sponsor:   National Institutes of Health Clinical Center (CC)
Completed - verified August 2015