Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Attentional Capacity and Working Memory in Coronary Artery Disease Patients: Impact of the Presence of a Sleep Apnea Syndrome and Chronic Effects of Treatment With CPAP

Conditions:   Obstructive Sleep Apnea;   Acute Coronary Syndrome
Intervention:   Device: CPAP treatment
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting - verified August 2015

Heart Rate Variability (HRV) Testing Compared With Exercise Stress Test in Hospitalized Patients With Chest Pain

Conditions:   Angina Pectoris;   Ischemic Heart Disease
Intervention:   Other: Heart rate monitor
Sponsor:   Meir Medical Center
Recruiting - verified August 2015

Clinical Cohort Study On The Relation Among Prescription, Syndrome and Disease of Turbid Phlegm and Blood Stasis for Coronary Heart Disease

Condition:   Coronary Artery Disease
Interventions:   Drug: Danlou Tablets;   Drug: Tongmai Yangxin Pills
Sponsor:   Tianjin University of Traditional Chinese Medicine
Recruiting - verified August 2015

Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery

Conditions:   Hypotension;   Postoperative Complications;   Acute Coronary Syndrome;   Heart Failure;   Coronary Occlusion;   Stroke;   Acute Kidney Injury;   Renal Insufficiency, Chronic;   Death
Interventions:   Drug: Liberal blood pressure management;   Drug: Tight blood pressure management
Sponsor:   Miodrag Filipovic, Prof. Dr. med.
Not yet recruiting - verified August 2015

An Investigation to Evaluate an Over-The-Wire FFR Infusion Microcatheter (HYPEREM™IC) for Measuring Fractional Flow Reserve (FFR)

Condition:   Coronary Artery Disease
Intervention:   Device: FFR Infusion Microcatheter and standard intra-venous (IV) infusion
Sponsor:   Diasolve Ltd
Not yet recruiting - verified August 2015

Effect of ACE-Inhibition on Microvascular Function in Women With Assessed Microvascular Dysfunction

Condition:   Microvascular Angina
Interventions:   Drug: Ramipril (ACE-inhibitor);   Drug: placebo
Sponsor:   Bispebjerg Hospital
Enrolling by invitation - verified August 2015

A Trial Evaluating Methods to Use Physical Activity to Improve Outcomes After Hospitalization for Acute Coronary Syndrome

Conditions:   Physical Activity;   Acute Coronary Syndrome
Interventions:   Behavioral: Financial-incentive based physical activity program;   Device: "Misfit Shine" Wearable Activity Tracking Device
Sponsor:   University of Pennsylvania
Not yet recruiting - verified August 2015

Platelet Inhibition After Pre-hospital Ticagrelor Using Fentanyl Compared to Morphine in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Fentanyl;   Drug: Morphine;   Drug: Ticagrelor;   Drug: Aspirin;   Drug: Unfractioned Heparin;   Procedure: Primary PCI
Sponsors:   Centre Hospitalier Universitaire Vaudois;   AstraZeneca
Not yet recruiting - verified August 2015

Comparison of Optical Coherence Tomographic Findings After Balloon Angioplasty With Two Different Paclitaxel-Coated Balloons for the Treatment of In-Stent Restenosis in Drug-Eluting Stents

Condition:   Coronary Artery Disease
Interventions:   Device: balloon angioplasty with Pantera Lux;   Device: balloon angioplasty with SeQuent Please
Sponsor:   Yonsei University
Not yet recruiting - verified August 2015

Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina

Condition:   Cardiovascular Diseases
Interventions:   Dietary Supplement: Beetroot Juice;   Dietary Supplement: Beetroot Juice
Sponsors:   Queen Mary University of London;   Imperial College London
Not yet recruiting - verified August 2015

Pilot Study of the Fantom Bioresorbable Scaffold (FANTOM I)

Condition:   Coronary Artery Disease
Intervention:   Device: Fantom Scaffold
Sponsor:   REVA Medical, Inc.
Active, not recruiting - verified August 2015

Evaluation of Antiplatelet Effects and Safety of Intraoperative Administration of Ticagrelor Versus Clopidogrel

Condition:   Coronary Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   Yongjian Wu
Recruiting - verified August 2015

Comparison of Ticagrelor vs. Prasugrel on Inflammation, Arterial Stiffness, Endothelial Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Coronary Stenting

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Ticagrelor;   Drug: Prasugrel
Sponsors:   Korea University Anam Hospital;   AstraZeneca
Recruiting - verified August 2015

FAST Feasibility Study

Condition:   Coronary Artery Disease
Intervention:   Device: Boston Scientific Fully Absorbable Scaffold
Sponsor:   Boston Scientific Corporation
Recruiting - verified August 2015

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Recruiting - verified August 2015

Effects of Electroacupuncture on Stress Response During Extubation of General Anesthesia in Elderly Patients

Condition:   Stress
Intervention:   Device: electro-acupuncture
Sponsor:   Shengjing Hospital
Recruiting - verified August 2015

Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial Hypercholesterolemia

Condition:   Familial Hypercholesterolemia
Interventions:   Other: Pre-lipid apheresis;   Other: Post-lipid apheresis
Sponsor:   Laval University
Not yet recruiting - verified August 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural Medical University ;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified August 2015

A Study to Obtain Additional Information on the Use of CorMatrix® CanGaroo ECM® Envelope

Condition:   Coronary Disease
Intervention:   Device: CorMatrix CanGaroo ECM Envelope
Sponsor:   CorMatrix
Not yet recruiting - verified August 2015

Identification of the Blood Microbiota in Patient Suffering From Myocardial Infraction

Conditions:   Coronary Disease;   Myocardial Infarction
Intervention:  
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2015

An Observational Prospective Study to Understand the Usage Pattern of Ticagrelor With ACS (Acute Coronary Syndrome)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Benefits of Exercise Training in Women With Ischemic Syndrome

Condition:   Microvascular Coronary Dysfunction
Intervention:   Behavioral: Exercise training
Sponsor:   Cedars-Sinai Medical Center
Not yet recruiting - verified August 2015

Differential Effect of High (200μg/kg/Min) Adenosine Dose on Fractional Flow Reserve in Patients Presenting Variation of FFR ≥0.05 During the Usual Dose of Adenosine Infusion (140μg/kg/Min).

Condition:   Coronary Artery Disease
Intervention:   Drug: Adenosine infusion at 200μg/Kg/min
Sponsor:   University of Patras
Recruiting - verified August 2015

Randomized Evaluation of Anagliptin Versus Sitagliptin On Low-density lipoproteiN Cholesterol in Diabetes Trial

Conditions:   Dipeptidyl-Peptidase 4 Inhibitors;   LDL Cholesterol;   Glycosylated Hemoglobin;   Diabetes Mellitus;   Coronary Disease
Interventions:   Drug: Anagliptin;   Drug: Sitagliptin
Sponsor:   Institute for Clinical Effectiveness, Japan
Recruiting - verified August 2015

Eplerenone in Heart Failure Treatment

Conditions:   Heart Failure;   Acute Myocardial Infarction;   Hypertension
Intervention:  
Sponsor:   Elpen Pharmaceutical Co. Inc.
Recruiting - verified August 2015

Chest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac Ischemia

Condition:   Chest Pain
Intervention:   Drug: Capsaicin
Sponsor:   Bassett Healthcare
Active, not recruiting - verified August 2015

Determine the Safety/Efficacy of Ticagrelor for Maintaining Patency of Arterio-Venous Fistulae Created for Hemodialysis

Conditions:   End Stage Renal Disease;   Vascular Access Patency
Interventions:   Drug: ticagrelor;   Drug: Placebo
Sponsors:   University of Virginia;   AstraZeneca
Recruiting - verified August 2015

Chest Pain Perception and Capsaicin Sensitivity

Condition:   Chest Pain
Intervention:   Drug: Capsaicin
Sponsor:   Bassett Healthcare
Active, not recruiting - verified August 2015

Long-term Follow-up of antithrombotIc Management Patterns in Acute Coronary Syndrome Patients in Asia-China Extension

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Effects of Pitavastatin on Insulin Sensitivity and Liver Fat

Conditions:   Obesity;   Fatty Liver, Nonalcoholic
Intervention:   Drug: pitavastatin
Sponsor:   Massachusetts General Hospital
Recruiting - verified August 2015

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified August 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Left Bundle Branch Block ECG Characteristics in the Evaluation of Acute Coronary Syndrome

Condition:   Left Bundle Branch Block
Intervention:   Other: None - no intervention, observational study
Sponsor:   Duke University
Terminated - verified August 2015

Improvement of Subjective Well-Being by Ranolazine Among Unrevascularized Chronic Stable Coronary Artery Disease Patients

Condition:   Angina
Interventions:   Drug: Ranolazine;   Drug: Sugar pill
Sponsors:   North Florida Foundation for Research and Education;   Gilead Sciences
Recruiting - verified August 2015

A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction

Conditions:   Heart Attack;   NSTEMI
Interventions:   Biological: AMI MultiStem cells;   Other: Sham
Sponsors:   Athersys, Inc;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2015

Magnetic Resonance Imaging for Global Atherosclerosis Risk Assessment

Conditions:   Cardiovascular Disease;   Atherosclerosis
Interventions:   Other: MRI;   Other: PET/MRI;   Other: Laboratory blood test
Sponsor:   Cedars-Sinai Medical Center
Recruiting - verified August 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified August 2015

PLATINUM Diversity

Conditions:   Atherosclerosis;   Coronary Artery Disease
Intervention:   Device: Percutaneous coronary intervention (Promus PREMIER)
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified August 2015

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2015

Impact of Breathing Maneuvers on the Oxygenation Supply of the Heart Assessed With MRI in Patients With Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Drug: Oxygen;   Other: Hyperventilation Breath-hold (HVBH);   Other: HVBH with Oxygen
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified August 2015

Safety, Tolerability, and Immunogenicity of the Ebola Chimpanzee Adenovirus Vector Vaccine (cAd3-EBO), VRC-EBOADC069-00-VP, in Healthy Adults

Condition:   Healthy Adult Immune Responses to Vaccine
Interventions:   Biological: VRC-EBOADC069-00-VP;   Biological: VRC-EBOADC076-00-VP
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting - verified August 2015

Study Of Costs Realized After Percutaneous Coronary intervenTion Employing Same Day Discharge

Condition:   Coronary Artery Disease
Intervention:   Procedure: Same day discharge
Sponsors:   Saint Joseph Mercy Health System;   Michigan Heart;   Blue Cross Blue Shield of Michigan Foundation
Terminated - verified August 2015

Telehealth Self-Management Program in Older Adults Living With Heart Failure in Health Disparity Communities

Condition:   Chronic Heart Failure
Interventions:   Device: Telehealth Self Management (TSM);   Other: Standard of Care
Sponsor:   North Shore Long Island Jewish Health System
Recruiting - verified August 2015

Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.

Condition:   Acute Coronary Syndrome
Interventions:   Drug: MEOPA and paracetamol;   Drug: Morphine
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2015

Canadian SCAD Study

Condition:   Spontaneous Coronary Artery Dissection
Intervention:  
Sponsors:   Cardiology Research UBC;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified August 2015

Using Feedback Reports to Improve Medication Adherence

Conditions:   Coronary Artery Disease;   Adherence
Interventions:   Behavioral: Individual Feedback;   Behavioral: Feedback Friend
Sponsor:   Philadelphia Veterans Affairs Medical Center
Active, not recruiting - verified August 2015

Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Intervention:   Other: blood sample
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified August 2015

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

Conditions:   Coronary Disease;   Coronary Stenosis
Interventions:   Procedure: FFR guided PCI;   Procedure: CABG
Sponsors:   Stanford University;   VZW Cardiovascular Research Center Aalst;   Catharina Hospital Eindhoven;   Golden Jubilee National Hospital;   University of California, Irvine;   Medtronic;   St. Jude Medical;   Genae;   King's College Hospital, London;   Houston Methodist DeBakey Heart and Vascular Center, Houston
Recruiting - verified August 2015

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Treatment 90 days DAPT;   Drug: Treatment 360 days DAPT
Sponsor:   Diagram B.V.
Recruiting - verified August 2015

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL112;   Biological: Placebo
Sponsor:   CSL Behring
Recruiting - verified August 2015

Aggressive hydraTion in Patients With ST -Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention to prevenT Contrast-Induced Nephropathy

Condition:   ST Elevation Myocardial Infarction
Interventions:   Drug: Receiving hydration with a 1 mL/kg bolus of intravenous isotonic saline (0.9% sodium chloride);   Drug: 3 mL/kg.hour bolus of intravenous isotonic saline (0.9% sodium chloride)
Sponsors:   Guangdong General Hospital;   Peking University First Hospital;   Chinese PLA General Hospital;   Fudan University
Recruiting - verified August 2015

Use of Abbott High Sensitivity Troponin I Assay In Acute Coronary Syndromes

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction;   Troponin
Intervention:  
Sponsors:   Minneapolis Medical Research Foundation;   Abbott Diagnostics Division;   Hennepin County Medical Center, Minneapolis
Active, not recruiting - verified August 2015

Aspirin Impact on Platelet Reactivity in Acute Coronary Syndrome Patients on Novel P2Y12 Inhibitors Therapy

Conditions:   Acute Coronary Syndrome;   Platelet Function and Reactivity Tests;   Novel P2Y12 Inhibitors
Intervention:   Drug: Aspirin
Sponsor:   Sheba Medical Center
Recruiting - verified August 2015

Differential Effect of Ticagrelor Versus Prasugrel Maintenance Dose on Endothelial Function of Peripheral Vessels in Patients With Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Endothelial Function
Interventions:   Drug: Ticagrelor;   Drug: Prasugrel
Sponsor:   University of Patras
Recruiting - verified August 2015

Offset of Ticagrelor's Effect on Endothelial Function as Assessed With Peripheral Arterial Tonometry (EndoPAT Assay)

Conditions:   Coronary Artery Disease;   Endothelial Function
Intervention:   Device: Peripheral arterial tonometry  (EndoPAT)
Sponsor:   University of Patras
Completed - verified August 2015

Ticagrelor vs High Dose Clopidogrel in Patients With ST Elevation Myocardial Infarction Post Fibrinolysis

Conditions:   ST Elevation Myocardial Infarction;   Fibrinolysis;   P2Y12 Inhibitor
Interventions:   Drug: Ticagrelor 180mg loading dose and 90mg bid maintenance dose;   Drug: Clopidogrel 600mg loading dose and 150mg maintenance dose
Sponsor:   University of Patras
Completed - verified August 2015

Remote Ischemic Preconditioning Induces Myocardial RISK Signaling Pathway Via High Mobility Group Box 1 Preconditioning in Patients Undergoing Valvular Heart Surgery

Condition:   Patients Undergoing Elective Lumbar Spinal Surgery
Interventions:   Procedure: Remote ischemic preconditioning at left upper arm;   Procedure: Control group
Sponsor:   Yonsei University
Recruiting - verified August 2015

Pioglitazone Regress Left Ventricular Mass in Type 2 Diabetes With Ischeamia Heart Disease

Conditions:   LVM;   Type 2 Diabetic Patients With IHD;   Endothelial Function
Interventions:   Drug: pioglitazone group;   Drug: Metformin group
Sponsor:   Xiang Guang-da
Completed - verified August 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Cognition and Exercise Training

Conditions:   Metabolic Syndrome;   Coronary Heart Disease;   Chronic Heart Failure
Interventions:   Other: high intensity interval training (HIIT);   Other: moderate intensity continuous exercise training
Sponsor:   Montreal Heart Institute
Recruiting - verified August 2015

Intensive Prevention Program After Myocardial Infarction

Conditions:   Myocardial Infarction.;   Prevention Harmful Effects.
Interventions:   Behavioral: Intensive Prevention Program;   Other: Standard medical and interventional therapy
Sponsors:   Herzzentrum Bremen;   Oldenburger Forschungs- und Entwicklungsinstitut für Informatik (OFFIS).
Recruiting - verified August 2015

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified August 2015

Alpha-lipoic Acid Reduces Left Ventricular Mass in Normotensive Type 2 Diabetic Patients With Coronary Artery Disease

Conditions:   Type 2 Diabetes;   Coronary Artery Disease;   Left Ventricular Mass
Intervention:   Drug: alpha-lipoic acid
Sponsor:   Wuhan General Hospital of Guangzhou Military Command
Completed - verified August 2015

Uninterrupted Clopidogrel Therapy Before Elective Colonoscopy Will Increase the Risk of Post-polypectomy Bleeding

Condition:   Gastrointestinal Bleeding
Interventions:   Drug: clopidogrel;   Drug: clopidogrel
Sponsor:   Chinese University of Hong Kong
Recruiting - verified August 2015

Surgical Pulmonary Vein Isolation Efficiency Study

Conditions:   Paroxysmal Atrial Fibrillation;   Coronary Artery Disease
Interventions:   Procedure: CABG, AVR or CABG+AVR and PVI;   Procedure: CABG, AVR or CABG+AVR
Sponsor:   Kuopio University Hospital
Terminated - verified August 2015

The GReek AntiPlatElet (GRAPE) Registry: A Multicenter Observational Prospective Investigation of Antiplatelet Treatment in Patients With Acute Coronary Syndrome Subjected to Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   University of Patras;   Hellenic Cardiological Society
Completed - verified August 2015

Drug Eluting Balloon for Prevention of Constrictive Remodeling

Conditions:   Coronary Disease;   Diabetes Mellitus
Interventions:   Device: Paclitaxel coated balloon catheter;   Device: uncoated balloon catheter "sprinter legend"
Sponsor:   Prof. Dr. med. Christoph Hehrlein
Recruiting - verified August 2015

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: aleglitazar;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

Study to Evaluate Effect of Nebivolol on Angina in Women With Microvascular Disease

Condition:   Microvascular Angina
Intervention:   Drug: Nebivolol
Sponsors:   Massachusetts General Hospital;   Forest Laboratories
Completed - verified August 2015

A Randomized Clinical Evaluation of the BioFreedom™ Stent

Conditions:   Stable Angina;   Ischemic Heart Disease Silent;   ST Elevation (STEMI) and Non-ST Elevation (NSTEMI) Myocardial Infarction;   In-stent Coronary Artery Restenosis;   Bleeding
Interventions:   Device: Biofreedom™ Drug Coated Stent (DCS);   Device: Gazelle™ Bare Metal Coronary Stent (BMS)
Sponsors:   Biosensors Europe SA;   European Cardiovascular Research  Center
Active, not recruiting - verified August 2015

A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: Placebo
Sponsor:   Genentech, Inc.
Completed - verified August 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Safety and Effectiveness of Intra-coronary Nitrite in Acute Myocardial Infarction

Conditions:   Myocardial Infarction;   Reperfusion Injury;   Myocardial Ischemia;   Cardiovascular Diseases
Interventions:   Drug: Sodium Nitrite;   Drug: Sodium Chloride Placebo
Sponsors:   Barts & The London NHS Trust;   Queen Mary University of London
Active, not recruiting - verified July 2015

Controlled Level EVERolimus in Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Everolimus;   Drug: Placebo
Sponsors:   University of Zurich;   Swiss National Science Foundation;   Novartis
Recruiting - verified August 2015

A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease

Condition:   Cardiovascular Disease, Coronary Heart Disease, Dyslipidemia, Peripheral Arterial Disease (PAD)
Interventions:   Other: Background care;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

Coronary Hybrid Revascularisation Study

Condition:   Significant Coronary Artery Disease
Intervention:   Procedure: Combined CABG and PCI
Sponsor:   Aarhus University Hospital Skejby
Active, not recruiting - verified August 2015

TAKO-TSUBO Cardiomyopathy and Genetic

Conditions:   Tako-TSUBO Cardiomyopathy;   Acute Coronary Syndrome
Intervention:  
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Fédération Française de Cardiologie
Active, not recruiting - verified August 2015

METHOD - Bone Marrow Derived Mononuclear Cells in Chronic Ischemic Disease

Condition:   Chronic Ischemic Heart Disease
Interventions:   Other: intramyocardial injection of BM cells;   Other: intramyocardial / intracoronary injection of BM cells;   Other: Best medical therapy
Sponsor:   Cardiocentro Ticino
Terminated - verified August 2015

IVUS Assessment of Atheroma Burden After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2015

Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain

Conditions:   Chest Pain;   Angina;   Angina Pectoris;   Coronary Artery Disease
Interventions:   Procedure: Stress Echocardiography;   Procedure: Coronary CT Angiography
Sponsors:   Montefiore Medical Center;   American Heart Association
Recruiting - verified August 2015

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

A Study of RO4905417 in Patients With Non ST-Elevation Myocardial Infarction (Non-STEMI) Undergoing Percutaneous Coronary Intervention

Condition:   Myocardial Infarction
Interventions:   Procedure: Percutaneous Coronary Intervention (PCI);   Drug: RO4905417;   Drug: RO4905417;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

Lipid Efficacy of the Extended Release Niacin/Laropiprant Combination in Patients With Cardiovascular Disease

Conditions:   Coronary Artery Disease;   Dyslipidemias
Interventions:   Drug: Extended release niacin/laropiprant;   Drug: placebo
Sponsors:   Daniel A. Siniawski;   Merck Sharp & Dohme Corp.
Terminated - verified August 2015

A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery

Condition:   Coronary Heart Disease, Graft Occlusion, Vascular
Interventions:   Drug: Placebo;   Drug: RO4905417
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography

Condition:   Coronary Artery Disease
Intervention:   Device: FFR
Sponsors:   HeartFlow, Inc.;   Harvard Clinical Research Institute;   Los Angeles Biomedical Research Institute;   Minneapolis Heart Institute Foundation
Completed - verified August 2015

The Effect of Melatonin on Ischemia-reperfusion Injury Following Acute Myocardial Infarction

Conditions:   Acute Myocardial Infarction;   Ischemia-reperfusion Injury
Interventions:   Drug: Melatonin, N-acetyl-5-methoxytryptamine;   Drug: Isotonic saline, Natrium chloride
Sponsor:   Herlev Hospital
Recruiting - verified August 2015

A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease

Condition:   Cardiovascular Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Terminated - verified August 2015

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

A Survey to Evaluate the Rate of Abnormal Glucose Tolerance Among Hong Kong Chinese Subjects With Coronary Heart Disease

Conditions:   Coronary Heart Disease;   Diabetes Mellitus
Intervention:  
Sponsor:   Chinese University of Hong Kong
Withdrawn - verified August 2015

Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina;   Acute Coronary Syndrome
Interventions:   Procedure: Coronary Computed Tomography Angiography;   Procedure: Stress Nuclear Myocardial Perfusion Imaging
Sponsors:   Montefiore Medical Center;   American Heart Association;   Albert Einstein College of Medicine of Yeshiva University
Completed - verified August 2015

A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients

Condition:   Coronary Heart Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Condition:   Coronary Heart Disease
Interventions:   Drug: Evidence-based medical care for Acute Coronary Syndrome;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

Left Ventricular Function Assessment After Acute Myocardial Infarction: Comparison Between Bi-, Three-dimensional and Cardiac Magnetic Resonance

Condition:   Acute Myocardial Infarction
Intervention:   Other: compare measurements of left ventricular volumes and LVEF (by Cardiac Magnetic Resonance and Echocardiography)
Sponsor:   Assistance Publique Hopitaux De Marseille
Completed - verified June 2008

Database Registry of the Intermountain Heart Collaborative Study

Conditions:   Coronary Artery Disease;   Electrophysiology;   Cardiovascular Disease
Intervention:  
Sponsor:   Intermountain Health Care, Inc.
Recruiting - verified August 2015

A Long Term Extension of Study NC19453 Evaluating Safety and Efficacy of RO4607381

Condition:   Coronary Heart Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

Carotid Plaque Regression With Statin Treatment Assessed by High Field Magnetic Resonance Imaging (MRI)

Condition:   Carotid Atherosclerosis
Intervention:  
Sponsor:   Medical College of Wisconsin
Withdrawn - verified August 2015

A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.

Condition:   Coronary Heart Disease
Interventions:   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

SDCC - Prospective Cohort Study of Chronic Renal Insufficiency

Condition:   Renal Insufficiency, Chronic
Intervention:  
Sponsors:   University of Pennsylvania;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Johns Hopkins University;   Case Western Reserve University;   University of Michigan;   University of Illinois at Chicago;   Tulane University;   Kaiser Permanente
Active, not recruiting - verified August 2015

Insulin Resistance Intervention After Stroke Trial

Conditions:   Stroke;   Myocardial Infarction;   Diabetes
Interventions:   Drug: pioglitazone;   Drug: placebo
Sponsors:   Yale University;   National Institute of Neurological Disorders and Stroke (NINDS);   Takeda Pharmaceuticals North America, Inc.
Active, not recruiting - verified August 2015

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