Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Noninvasive Neuromonitoring of Surgery of the Thoracic Aorta

Conditions:   Cardiopulmonary Arrest;   Aortic Aneurysm, Thoracic;   Aortic Diseases;   Coronary Artery Disease
Intervention:  
Sponsors:   Helsinki University;   GE Healthcare
Completed - verified August 2016

Efficacy Study of Hydroxychloroquine to Treat High-risk Coronary Artery Disease.

Condition:   Coronary Artery Disease
Interventions:   Drug: Hydroxychloroquine Sulfate Tablets;   Drug: Placebo Tablets
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Not yet recruiting - verified July 2016

BMX Alpha Registry: a Post-market Registry of the BioMatrix Alpha TM

Conditions:   Coronary Artery Disease;   Stable Angina;   Ischemia;   Acute Coronary Syndrome;   NSTEMI;   STEMI
Intervention:   Device: BioMatrix AlphaTM
Sponsors:   Biosensors Europe SA;   European Cardiovascular Research Center
Not yet recruiting - verified August 2016

The Effect of Dan-shen Extract On Lipoprotein Associated PHospholipase A2 Levels IN Patients With Stable Angina Pectoris

Conditions:   Angina, Stable;   Inflammation
Interventions:   Drug: Dan-shen extract;   Drug: Placebo;   Other: Standard medical care
Sponsors:   Taizhou Fourth People's Hospital;   Shanghai 10th People's Hospital
Not yet recruiting - verified August 2016

Transepicardial With Transseptal Autologous CD 133+ Bone Marrow Cell Implantation in Patient Following CABG Surgery

Condition:   Coronary Artery Disease
Intervention:   Biological: Transepicardial with Transseptal CD 133+ Implantation
Sponsor:   National Cardiovascular Center Harapan Kita Hospital Indonesia
Recruiting - verified August 2016

BIOTRONIK Orsiro Pre-Marketing Registration

Condition:   Coronary Artery Disease
Intervention:   Device: Coronary Stent
Sponsor:   Biotronik (Beijing) Medical Device Ltd.
Recruiting - verified August 2016

Thin Strut Sirolimus-eluting Stent in All Comers Population vs Everolimus-eluting Stent

Condition:   Coronary Stenosis
Interventions:   Device: SUPRAFLEX;   Device: XIENCE
Sponsors:   ECRI bv;   Sahajanand Medical Technologies Pvt. Ltd.
Not yet recruiting - verified August 2016

The Assessment of Large and Small Artery Elasticity for the Early Detection of Cardiovascular Disease

Conditions:   Cardiovascular Diseases;   Vascular Stiffness
Intervention:  
Sponsor:   St. Boniface General Hospital Research Centre
Recruiting - verified August 2016

China Senile Valvular Heart Disease Cohort Study

Condition:   Heart Valve Diseases
Intervention:  
Sponsors:   China National Center for Cardiovascular Diseases;   Ministry of Science and Technology of the People´s Republic of China
Not yet recruiting - verified August 2016

Instantaneous Wave-Free Ratio and Fractional Flow Reserve for the Assessment of Non Culprit Lesions in Patients With ST-segment Elevation Myocardial Infarction

Condition:   ST Segment Elevation Myocardial Infarction
Intervention:   Other: FFR and iFR
Sponsor:   Azienda Ospedaliera San Camillo Forlanini
Recruiting - verified August 2016

Stem Cells Therapy in Advanced Heart Failure

Condition:   Congestive Heart Failure
Intervention:   Drug: stem cells infusion
Sponsor:   Second University of Naples
Completed - verified August 2016

MANAGING ANGER IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION (MAPAMI)

Condition:   Anger Management Therapy [F04.754.137.087]
Intervention:   Behavioral: Anger control therapy
Sponsor:   Instituto de Cardiologia do Rio Grande do Sul
Enrolling by invitation - verified September 2015

A Clinical Research of Qi Deficiency and Blood Stasis Syndrome (Different Disease With Syndrome)

Condition:   Ischemic Heart Failure
Interventions:   Drug: Yiqi prescription;   Drug: Huoxue prescription;   Drug: Buyang huanwu decoction;   Drug: QISHEN YIQI DRIPPING PILLS;   Drug: Placebo 1;   Drug: Placebo 2
Sponsor:   Zhu Mingjun
Recruiting - verified August 2016

Quantitation of Left Ventricular Ejection Fraction Change From Early Exercise Gated Stress/Rest Tc-99m CZT-SPECT MPI

Condition:   Coronary Artery Disease
Interventions:   Other: Single photon emission computed tomography myocardial perfusion imaging;   Device: novel cadmium-zinc-telluride (CZT) SPECT cameras
Sponsor:   Sheba Medical Center
Not yet recruiting - verified August 2016

OCT Based Edge and In-stent Vascular Response After Cordimax Stent in patIents With NSTE-ACS

Conditions:   Angina, Unstable;   Non-ST-Segment Elevation Myocardial Infarction
Interventions:   Device: OCT;   Device: eLuting stent
Sponsor:   Xijing Hospital
Not yet recruiting - verified May 2016

Quantitation of Cardiac Output Change by Impedance Cardiography in Subjects Undergoing Exercise Gated Stress/Rest Tc-99m CZT-SPECT MPI

Condition:   Coronary Artery Disease
Interventions:   Device: Single photon emission computed tomography myocardial perfusion imaging;   Other: exercise
Sponsor:   Sheba Medical Center
Not yet recruiting - verified August 2016

Effect of Pitavastatin on Erythrocyte Membrane Fatty Acid Contents in Patients With Chronic Kidney Disease

Condition:   Chronic Kidney Disease
Interventions:   Drug: Pitavastatin;   Drug: Atorvastatin
Sponsor:   Dong-A University
Active, not recruiting - verified August 2016

The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock Patients

Condition:   Cardiogenic Shock
Interventions:   Procedure: Simultaneous RRT;   Procedure: Standard care
Sponsor:   Beijing Anzhen Hospital
Recruiting - verified August 2016

Familial Hypercholesterolemia Amongst Patients With Acute Coronary Syndrome

Conditions:   Familial Hypercholesterolemia;   Cardiac Event;   Acute Coronary Syndrome
Intervention:   Other: Registry
Sponsor:   Isfahan University of Medical Sciences
Recruiting - verified August 2016

Coronary Sinus Blood Sevoflurane and Desflurane Concentration and Lactate Changes in Patients Undergoing Heart Surgery

Conditions:   Myocardial Reperfusion Injury;   Heart Diseases;   Postoperative Complications
Intervention:   Biological: Blood samples
Sponsors:   University of Malaya;   University of Edinburgh
Not yet recruiting - verified August 2016

MyoVista Measurements in Patients With Atherosclerosis and CAD

Conditions:   Coronary Artery Disease (CAD);   Atherosclerosis
Intervention:   Device: MyoVista
Sponsors:   Los Angeles Biomedical Research Institute;   Heart Test Laboratories Inc.
Recruiting - verified August 2016

Coronary Flow Reserve to Assess Cardiovascular Inflammation (CIRT-CFR)

Conditions:   Coronary Heart Disease;   Metabolic Syndrome;   Diabetes Mellitus
Interventions:   Radiation: PET scan;   Radiation: Echocardiogram
Sponsors:   Brigham and Women's Hospital;   Ottawa Heart Institute Research Corporation;   University of Alabama at Birmingham
Recruiting - verified August 2016

INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart Failure

Conditions:   Heart Failure;   Myocardial Infarction
Interventions:   Biological: High Dose Trivalent Influenza Vaccine;   Biological: Standard Dose Quadrivalent Influenza Vaccine
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   University of Wisconsin, Madison;   University of Toronto;   Boston VA Research Institute, Inc.;   Patient-Centered Outcomes Research Institute
Recruiting - verified August 2016

A Comparative Evaluation of the Extent of Neointima Formation at 1 Month and 2 Months After Implantation Using OCT

Conditions:   Coronary Artery Disease;   Stable Angina Pectoris;   Unstable Angina Pectoris
Interventions:   Device: BuMA Supreme™ stent;   Device: Xience V/Prime stent
Sponsor:   Sino Medical Sciences Technology Inc.
Recruiting - verified August 2016

Comparison of 2 Hemostasis Techniques After Transradial Coronary

Condition:   Coronary Artery Disease With Myocardial Infarction
Interventions:   Device: Standardized compressive dressing;   Device: Hemostasis with TerumoBand®
Sponsor:   Hospital de Clinicas de Porto Alegre
Recruiting - verified August 2016

Cardiopulmonary and Metabolic Responses to Early Exercise in Patients After Coronary Arterial Bypass Grafting

Conditions:   Acute Myocardial Infarction: Rehabilitation Phase;   Coronary Artery Bypass Graft Triple Vessel;   Physical Activity
Intervention:   Other: Cycle ergometer exercise rehabilitation protocol
Sponsor:   Federal University of São Paulo
Recruiting - verified August 2016

Myocardial Protection With Phosphocreatine in High-RIsk Cardiac SurgEry Patients

Conditions:   Cardiac Surgical Procedures;   Heart Valve Prosthesis Implantation
Interventions:   Drug: Phosphocreatine sodium tetrahydrate after anaesthesia induction;   Drug: 5% Glucose after anaesthesia induction;   Drug: Phosphocreatine sodium tetrahydrate added to cardioplegia;   Drug: 5% Glucose;   Drug: Phosphocreatine sodium tetrahydrate after heart recovery;   Drug: 5% Glucose after heart recovery;   Drug: Phosphocreatine sodium tetrahydrate after ICU admission;   Drug: 5% Glucose after ICU admission
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified August 2016

High Intensity Interval Training in UK Cardiac Rehabilitation Programmes

Condition:   Coronary Disease
Intervention:   Other: High intensity interval training
Sponsors:   University Hospitals Coventry and Warwickshire NHS Trust;   Cardiff Metropolitan University;   City Health Care Partnership CIC (Hull);   University of Hull;   Aneurin Bevan University Heath Board;   Atrium Health, Coventry;   University of Bangor;   University of Warwick
Recruiting - verified August 2016

A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL_112;   Other: Placebo
Sponsor:   CSL Behring
Recruiting - verified August 2016

Ultrapower; a Minimally Invasive Tool for Evaluation of Total Cardiac Power

Condition:   Cardiac Diseases
Intervention:   Other: Comparison of different methods of calculating cardiac power
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital
Recruiting - verified August 2016

Shorter Course Radiation for the Treatment of Breast Cancer That Has Spread to Lymph Nodes

Condition:   Breast Cancer
Intervention:   Radiation: Adjuvant Hypofractionated Radiation
Sponsor:   University of Colorado, Denver
Recruiting - verified August 2016

Ranolazine a Potential New Therapeutic Application

Condition:   Myocardial Stunning
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsor:   Policlinico Universitario Agostino Gemelli
Not yet recruiting - verified August 2016

Accelerated Rule Out of Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Procedure: Accelerated, combined biomarker rule-out strategy for MI
Sponsor:   Aarhus University Hospital Skejby
Recruiting - verified August 2016

Influence of Severe Heart Failure to Function and Molecular Biological Parameters of Catabolism in the Human Diaphragm and Peripheral Skeletal Muscle

Conditions:   Heart Failure;   Ischemic Myocardiopathy;   Dilatative Myocardiopathy
Interventions:   Other: Biopsy of the diaphragmatic muscle;   Other: Skeletal muscle biopsy
Sponsor:   Norman Mangner
Recruiting - verified August 2016

Supernormal Oxygen Delivery for Elderly Surgical Patients

Condition:   Femoral Fractures
Interventions:   Procedure: SV maximization;   Procedure: supernormal DO2
Sponsor:   Guangzhou First Municipal People’s Hospital
Recruiting - verified August 2016

Which Platelet Function Test Best Reflects the In Vivo Plasma Concentrations of Ticagrelor and Its Active Metabolite?

Conditions:   Infarction;   Myocardial Infarction;   Cardiovascular Diseases;   Heart Diseases;   Ischemia;   Myocardial Ischemia;   Necrosis;   Pathologic Processes;   Vascular Diseases
Intervention:  
Sponsor:   Collegium Medicum w Bydgoszczy
Completed - verified August 2016

Clinical Performance Evaluation of AQT90 FLEX TnI and TnT

Condition:   Myocardial Infarction
Intervention:  
Sponsor:   Radiometer Medical ApS
Recruiting - verified August 2016

Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study

Condition:   Unstable Angina Pectoris
Interventions:   Drug: Pulverized ticagrelor sublingually;   Drug: Pulverized ticagrelor orally;   Drug: Integral ticagrelor
Sponsor:   Collegium Medicum w Bydgoszczy
Active, not recruiting - verified August 2016

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified August 2016

Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study

Conditions:   Vascular Inflammation;   Atherosclerotic Cardiovascular Disease
Interventions:   Drug: Low dose methotrexate;   Drug: Placebo
Sponsors:   Icahn School of Medicine at Mount Sinai;   Brigham and Women's Hospital;   Massachusetts General Hospital;   St. Michael's Hospital, Toronto;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

Aiming Towards Evidence Based Interpretation of Cardiac Biomarkers in Patients Presenting With Chest Pain

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   Haukeland University Hospital;   Helse Stavanger HF
Recruiting - verified August 2016

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

Conditions:   Secondary Prevention;   Stroke;   Ischemic Heart Disease;   Coronary Heart Disease
Interventions:   Drug: Acetylsalicylic Acid (Asprin, BAYE4465);   Drug: Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
Sponsor:   Bayer
Recruiting - verified August 2016

Use of 99mTc Tilmanocept for Imaging Arterial Inflammation

Condition:   HIV
Intervention:   Other: Arterial Imaging
Sponsors:   Massachusetts General Hospital;   Navidea Biopharmaceuticals
Enrolling by invitation - verified August 2016

XIENCE Xpedition Everolimus-Eluting Coronary Stent Japan Post Marketing Surveillance (XIENCE Xpedition SV Japan PMS)

Conditions:   Ischemic Heart Disease;   Angina Pectoris;   Coronary Artery Disease;   Myocardial Ischemia
Intervention:   Device: XIENCE Xpedition 2.25 mm stent
Sponsor:   Abbott Vascular
Active, not recruiting - verified August 2016

COOL AMI EU Pilot Trial to Assess Cooling as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Device: Cooling + PCI;   Device: PCI only
Sponsor:   ZOLL Circulation, Inc., USA
Recruiting - verified August 2016

Impact of Daylight on Patients With Acute Myocardial Infarction

Conditions:   Coronary Arteriosclerosis;   Myocardial Infarction
Interventions:   Other: Day Light;   Other: Room Light
Sponsor:   University of Colorado, Denver
Recruiting - verified August 2016

The Adherence and Knowledge Exchange Heart and Stroke Medicines Study

Condition:   Myocardial Infarction
Intervention:   Behavioral: physician-facing app and patient-facing messages
Sponsors:   Duke Kunshan University;   Population Health Research Institute;   Fudan University;   Hainan Provincial Nongken General Hospital
Completed - verified November 2015

Stress Ulcer Prophylaxis in the Intensive Care Unit

Conditions:   Gastrointestinal Bleeding;   Stress Ulcers
Interventions:   Drug: Pantoprazole;   Other: Saline (0.9%)
Sponsors:   Dr. Morten Hylander Møller;   Rigshospitalet, Denmark;   Copenhagen Trial Unit, Center for Clinical Intervention Research
Recruiting - verified August 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified August 2016

Fenofibrate Treatment in SCI

Conditions:   Spinal Cord Injury;   Dyslipidemia
Interventions:   Drug: Fenofibrate;   Other: No intervention
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

Prospective Registry of Acute Coronary Syndromes in Ferrara

Condition:   Acute Coronary Syndromes
Intervention:   Other: prospective collection of data and follow-up
Sponsor:   University Hospital of Ferrara
Recruiting - verified August 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2016

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study

Condition:   Cost Sharing, Acute Coronary Syndrome,
Intervention:   Other: Study voucher card
Sponsors:   AstraZeneca;   Duke Clinical Research Institute
Recruiting - verified August 2016

Frailty in Elderly Patients Receiving Cardiac Interventional Procedures

Condition:   Aged
Intervention:   Other: frailty evaluation
Sponsor:   University Hospital of Ferrara
Recruiting - verified August 2016

Effects of Linagliptin on Endothelial Function

Conditions:   Type 2 Diabetes;   Coronary Artery Disease
Interventions:   Drug: Linagliptin;   Drug: Placebo
Sponsor:   Medical University of Graz
Active, not recruiting - verified August 2016

The Health Impact of High Intensity Exercise Training With Intervals During Cardiac Rehabilitation

Conditions:   Heart Disease;   Heart Attacks
Interventions:   Other: High intensity interval training (HIIT);   Other: Standard care
Sponsors:   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Edge Hill University
Completed - verified August 2016

Mitochondrial-related Platelet Transcript Expression Levels in Pre-diabetic Subjects Randomized to Metformin or Placebo

Condition:   Prediabetes
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsor:   University of Utah
Recruiting - verified August 2016

Coronary Flow Reserve Following Orbital Atherectomy

Condition:   Coronary Artery Disease
Intervention:   Device: Volcano FloWire
Sponsor:   Cardiovascular Systems Inc
Completed - verified August 2016

Evaluation of Myocardial Viability : Dual Energy Cardiac CT vs. Cardiac MRI

Condition:   Myocardial Infarction
Intervention:   Radiation: second propeller arm scanner
Sponsor:   University Hospital, Rouen
Recruiting - verified August 2016

Switching From Ticagrelor to Clopidogrel in Patients With Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsor:   University of Florida
Recruiting - verified August 2016

Effects of Pitavastatin on Insulin Sensitivity and Liver Fat

Conditions:   Obesity;   Fatty Liver, Nonalcoholic
Interventions:   Drug: pitavastatin;   Other: PLACEBO
Sponsor:   Massachusetts General Hospital
Recruiting - verified August 2016

Perioperative Assessment of Right Ventricular Function and Venous Return in Patients With Epithelial Ovarian Cancer Undergoing Cytoreductive Surgery (Gyn Right) - Pilot Study

Condition:   Right Ventricular Function and Venous Return
Intervention:  
Sponsor:   Charite University, Berlin, Germany
Withdrawn - verified August 2016

Effect of Cilostazol on Coronary Artery Stenosis and Plaque Characteristics in Patients With T2DM

Condition:   Coronary Artery Disease
Interventions:   Drug: Cilostazol;   Drug: Aspirin
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified August 2016

A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction

Conditions:   Heart Attack;   NSTEMI
Interventions:   Biological: AMI MultiStem cells;   Other: Sham
Sponsors:   Athersys, Inc;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Condition:   Hypercholesterolemia
Intervention:   Biological: Evolocumab
Sponsor:   Amgen
Active, not recruiting - verified August 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified August 2016

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Conditions:   Stroke;   Secondary Prevention
Interventions:   Drug: optional ASA as comedication;   Drug: placebo to ASA;   Drug: placebo to optional ASA as comedication;   Drug: placebo to dabigatran etexilate;   Drug: ASA 100 mg;   Drug: dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2016

Effects of Combined Therapy With Statin Plus Fenofibrate on Coronary Atherosclerotic Plaque Compared With Statin Alone

Condition:   Coronary Artery Disease
Interventions:   Drug: Rosuvastatin and fenofibrate;   Drug: Rosuvastatin alone
Sponsors:   Gachon University Gil Medical Center;   Daewoong Pharmaceutical Co. LTD.
Recruiting - verified August 2016

First-in-man Trial Examining the Safety and Efficacy of BuMA Supreme and Resolute Integrity in Patients With de Novo Coronary Artery Stenosis

Condition:   Coronary Artery Disease
Interventions:   Device: BuMA Supreme Biodegradable drug coating coronary stent system;   Device: Resolute Integrity durable polymer stent system
Sponsor:   Sino Medical Sciences Technology Inc.
Active, not recruiting - verified August 2016

Magnetic Nanoparticles System in Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   Far Eastern Memorial Hospital;   National Taiwan University Hospital
Recruiting - verified August 2016

An Intervention to Reduce Delirium After Cardiac Surgery

Conditions:   Delirium;   Congenital Heart Disease;   Coronary Artery Disease;   Heart Valve Disease
Interventions:   Procedure: Remote ischemic pre-conditioning;   Behavioral: Delirium Assessment
Sponsor:   Johns Hopkins University
Completed - verified August 2016

Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.

Condition:   Acute Coronary Syndrome
Interventions:   Drug: MEOPA and paracetamol;   Drug: Morphine
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2016

Integrating Depression Care in Acute Coronary Syndromes Care in China

Conditions:   Acute Coronary Syndromes;   Depression
Intervention:   Other: Integrated care model for ACS and depression
Sponsors:   The George Institute for Global Health, China;   National Institute of Mental Health (NIMH);   Peking University Sixth Hospital
Recruiting - verified August 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified August 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified August 2016

XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS) China Single-Arm Study

Conditions:   Angioplasty;   Cardiovascular Disease;   Coronary Artery Disease;   Coronary Heart Disease;   Coronary Restenosis;   Myocardial Infarction;   Stent Thrombosis;   Vascular Disease
Intervention:   Device: XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS)
Sponsor:   Abbott Vascular
Active, not recruiting - verified August 2016

Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Active, not recruiting - verified August 2016

Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

Condition:   Coronary Artery Disease
Intervention:   Drug: Gadobutrol (Gadovist, BAY86-4875)
Sponsor:   Bayer
Active, not recruiting - verified August 2016

Intensive Prevention Program After Myocardial Infarction

Conditions:   Myocardial Infarction.;   Prevention Harmful Effects.
Interventions:   Behavioral: Intensive Prevention Program;   Other: Standard medical and interventional therapy
Sponsors:   Herzzentrum Bremen;   Oldenburger Forschungs- und Entwicklungsinstitut für Informatik (OFFIS).
Active, not recruiting - verified August 2016

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified August 2016

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound

Condition:   Hypercholesterolemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo
Sponsor:   Amgen
Completed - verified August 2016

Mindful Hearts Study

Conditions:   Cardiovascular Disease;   Psychological Stress;   Stroke;   Coronary Artery Disease
Interventions:   Behavioral: Mindfulness Based Stress Reduction;   Behavioral: Health Education Program
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified August 2016

Hybrid Effectiveness-Implementation Study to Improve Clopidogrel Adherence

Conditions:   Cardiovascular Disease;   Acute Coronary Syndrome
Intervention:   Other: Multifaceted Intervention with pharmacist and IVR
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

CPR Training: Video Self-Instruction Kit or Video-Only

Conditions:   Cardiovascular Risk Factors;   Coronary Disease;   Cardiac Arrest
Interventions:   Other: CPR Training using the Family and Friends CPR Anytime Video Self Instruction;   Other: Implementation of a Hospital-based CPR Training Model;   Other: Follow-up prompting to encourage skill retention
Sponsor:   University of Pennsylvania
Active, not recruiting - verified August 2016

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Completed - verified August 2016

Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack

Conditions:   Heart Failure;   Myocardial Infarction
Interventions:   Drug: mecasermin;   Drug: mecasermin;   Drug: 0.9% sodium chloride injection
Sponsor:   University College Cork
Active, not recruiting - verified August 2016

Telemonitoring During Phase 2-3 Cardiac Rehabilitation

Condition:   Ischemic Heart Disease
Interventions:   Device: physical activity monitors;   Other: No physical activity monitors
Sponsor:   Jessa Hospital
Completed - verified August 2016

International Survey of Acute Coronary Syndromes in Transitional Countries

Conditions:   Acute Coronary Syndrome;   Unstable Angina Pectoris;   Myocardial Infarction;   Coronary Disease
Intervention:  
Sponsor:   University of Bologna
Recruiting - verified August 2016

Hormones and Sexual Function Predict Outcomes in Revascularized Men With Diabetes

Conditions:   Androgen Deficiency;   AD;   Erectile Dysfunction;   ED;   Diabetes Mellitus;   Coronary Artery Disease;   Coronary Revascularization
Intervention:  
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified August 2016

16 Year Follow-up of the Erlangen Fitness and Prevention Study.

Conditions:   Osteoporosis;   Osteopenia;   Early Postmenopause
Intervention:   Procedure: physical exercise
Sponsors:   University of Erlangen-Nürnberg Medical School;   Behinderten- und Versehrten-Sportverband Bayern e.V.;   Netzwerk Knochengesundheit e.V.
Active, not recruiting - verified August 2016

PREdisposition Genetical in Cardiac Insufficiency = Genetic Predisposition to Heart Failure

Condition:   ST Elevation (STEMI) Myocardial Infarction of Other Sites
Intervention:   Other: Cohort
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified August 2016

MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use

Conditions:   Acne Vulgaris;   Allergic Rhinitis;   Anxiety;   Asthma;   Back Pain;   Prostatic Hyperplasia;   Bursitis;   Chronic Obstructive Pulmonary Disease;   Cough;   Coronary Artery Disease;   Depression;   Diabetes Mellitus;   Diarrhea;   Gastroesophageal Reflux;   Fibromyalgia;   Headache;   HIV Infections;   Hypothyroidism;   Hyperlipidemia;   Hypertension;   Influenza;   Sleep Initiation and Maintenance Disorders;   Irritable Bowel Syndrome;   Knee Pain;   Migraine Disorders;   Obesity;   Obstructive Sleep Apnea;   Osteoarthritis;   Senile Osteoporosis;   Colonoscopy;   Mammography;   Shoulder Pain;   Sinusitis;   Smoking Cessation;   Tobacco Use Cessation;   Menopause;   Urinary Incontinence;   Urinary Tract Infection;   Vaccination;   Vaginitis;   Vertigo
Intervention:   Other: health information prescription
Sponsors:   University of Missouri-Columbia;   National Library of Medicine (NLM)
Completed - verified August 2016

The SMARTEX Heart Failure Study

Condition:   Heart Failure
Interventions:   Behavioral: Aerobic Interval Training;   Behavioral: Moderate continues training;   Behavioral: Recommendation of regular moderate exercise
Sponsors:   Norwegian University of Science and Technology;   University Hospital, Antwerp;   UMC Utrecht;   Technische Universität München;   Heartcenter Leipzig GmbH;   Bispebjerg Hospital;   St. Olavs Hospital;   Helse Stavanger HF
Completed - verified August 2016

Can Hypothermia be Incorporated Into Primary Angioplasty for Heart Attack?

Condition:   ST-Elevation Myocardial Infarction
Intervention:   Device: Life Recovery Systems ThermoSuit
Sponsor:   Life Recovery Systems
Not yet recruiting - verified August 2016

SDCC - Prospective Cohort Study of Chronic Renal Insufficiency

Condition:   Renal Insufficiency, Chronic
Intervention:  
Sponsors:   University of Pennsylvania;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Johns Hopkins University;   Case Western Reserve University;   University of Michigan;   University of Illinois at Chicago;   Tulane University;   Kaiser Permanente
Active, not recruiting - verified August 2016

Measuring Electrical Resistance of Different Tissues on the Outer Surface of the Heart

Conditions:   Cardiomyopathies;   Ventricular Dysfunction;   Myocardial Infarction;   Arrhythmia
Intervention:  
Sponsors:   University of Pennsylvania;   Biosense Webster, Inc.
Terminated - verified August 2016

Exercise-training Before Coronary Artery Bypass Graft (CABG)

Conditions:   Angina;   Coronary Artery Disease
Intervention:   Behavioral: Exercise training
Sponsor:   Norwegian University of Science and Technology
Recruiting - verified August 2016

The CLARICOR Trial: Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease

Conditions:   Heart Disease;   Cardiovascular Disease
Intervention:   Drug: clarithromycin
Sponsors:   Copenhagen Trial Unit, Center for Clinical Intervention Research;   Danish Heart Foundation;   Copenhagen Hospital Corporation;   The Danish Medical Research Council;   The 1991 Pharmacy Foundation;   Abbott
Completed - verified August 2016