Congenital Heart Defects

Clinical Trial Finder

Many patients with congenital heart defects are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Motor Development of Children That Have Surgery as Newborns for Complex Congenital Heart Disease

Condition:   Heart Defects, Congenital
Intervention:  
Sponsors:   Advocate Health Care;   Advocate Center for Pediatric Research;   University Medical Center Groningen
Recruiting - verified May 2016

Cardiac Stem/Progenitor Cell Infusion in Univentricular Physiology (APOLLON Trial)

Conditions:   Hypoplastic Left Heart Syndrome;   Single Ventricle
Intervention:   Genetic: Autologous cardiac stem cells (JRM-001)
Sponsor:   Japan Regenerative Medicine Co., Ltd.
Not yet recruiting - verified May 2016

Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency Department

Condition:   Syncope
Intervention:  
Sponsor:   University of Turin, Italy
Recruiting - verified May 2016

Effect of Resistance Training in Adults With Complex Congenital Heart Disease

Condition:   Congenital Heart Defect
Intervention:   Behavioral: Home based resistance training
Sponsor:   Umeå University
Recruiting - verified December 2015

Right Lateral Positioning of Postoperative Pediatric Cardiac Surgery

Condition:   Heart Defects, Congenital
Interventions:   Procedure: Right lateral position (2 hours);   Procedure: Left lateral position (30 minutes);   Procedure: Supine position (30 minutes);   Procedure: Left lateral position (2 hours);   Procedure: Supine position (2 hours)
Sponsor:   Assiut University
Recruiting - verified January 2016

Fresh Frozen Plasma and Plasmalyte ® for Priming Cardiopulmonary Bypass in Infants and Children

Condition:   Congenital Heart Disease
Interventions:   Procedure: Surgery with CPB;   Other: Fresh Frozen Plasma;   Other: Plasmalyte
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Recruiting - verified May 2016

Quality of Life in Young Adults With Congenital Heart Disease

Condition:   Congenital Heart Disease
Intervention:   Other: no intervention
Sponsor:   University Children's Hospital, Zurich
Recruiting - verified May 2016

The Role of the Pulmonary Vasculature in the Fontan Circulation

Conditions:   Congenital Heart Disease;   Fontan Operation;   Pulmonary Vascular Resistance;   Pulmonary Vascular Remodeling
Intervention:  
Sponsor:   University Medical Center Groningen
Recruiting - verified May 2016

Pulmonic SAPIEN XT THV

Condition:   Pulmonary Valve Malfunction
Intervention:   Other: SAPIEN XT
Sponsors:   Institut für Pharmakologie und Präventive Medizin;   Estimate, GmbH
Active, not recruiting - verified December 2015

Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery

Conditions:   Hypertension, Pulmonary;   Ventricular Dysfunction, Left
Intervention:   Drug: IK-3001
Sponsor:   Mallinckrodt
Completed - verified May 2016

The Genetic Basis of Congenital Heart Disease in Africa

Conditions:   Congenital Heart Disease;   Heart Disease
Intervention:  
Sponsors:   National Human Genome Research Institute (NHGRI);   University of Lagos, Nigeria;   Uganda Heart Institute, Kampala, Uganda
Recruiting - verified December 2015

Evaluating Precision of Therapy - Milrinone

Condition:   Congenital Heart Disease
Intervention:   Drug: Milrinone
Sponsor:   The Hospital for Sick Children
Recruiting - verified May 2016

Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aortic Dissection.

Conditions:   Turner Syndrome;   Aortic Aneurysm;   Ischemic Heart Disease;   Hypertension;   Congenital Heart Defect
Intervention:  
Sponsor:   University of Aarhus
Active, not recruiting - verified June 2015

Myocardial Perfusion and Scarring in Congenital Heart Disease

Condition:   Congenital Heart Disease
Intervention:  
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   Children's Research Institute;   Suburban Hospital
Recruiting - verified May 2016

Real-time MRI Right Heart Catheterization Using Passive Catheters

Conditions:   Caridovascular Disease;   Congenital Heart Disease;   Pulmonary Hypertension
Interventions:   Device: Balloon catheter for right heart catheterization;   Drug: Gadopentate Dimeglumine (Gadolinium); Contrast Agent;   Procedure: Right Heart Catheterization;   Procedure: Cardiac Real-time MRI;   Procedure: Vascular Hemostasis
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified March 2016

Cardiovascular Disease Screening

Conditions:   Congenital Heart Disease;   Atherosclerosis;   Myocardial Ischemia;   Myocardial Infarction;   Acquired Heart Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2016

Identification of Genes Expressed in Atherosclerotic Plaque

Condition:   Atherosclerosis
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified March 2016

Cardiovascular Magnetic Resonance Imaging of Pediatric Normal Volunteers

Condition:   Healthy
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified March 2016

Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular Disease

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Defect, Congenital Heart;   Heart Septal Defects, Ventricular;   Heart Septal Defects, Atrial;   Endocardial Cushion Defects
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified December 2004

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