Congenital Heart Defects

Clinical Trial Finder

Many patients with congenital heart defects are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

L-Citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects

Condition:   Acute Lung Injury
Interventions:   Drug: L-citrulline;   Other: Placebo
Sponsor:   Asklepion Pharmaceuticals, LLC
Recruiting - verified September 2016

The Human Trisome Project Biobank

Conditions:   Down Syndrome;   Trisomy 21
Sponsor:   University of Colorado, Denver
Recruiting - verified September 2016

Human Fibrinogen Concentrate in Pediatric Cardiac Surgery

Conditions:   Hypofibrinogenemia;   Afibrinogenemia;   Bleeding Disorders
Interventions:   Drug: RiaStAP;   Drug: Saline
Sponsor:   Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Not yet recruiting - verified September 2016

Post-market Clinical Follow-up Study With Magnetic Resonance Imaging Conditional Guide Wire

Condition:   Congenital Heart Defect
Interventions:   Procedure: pressure gradient measurement;   Device: MRWire
Sponsors:   Nano4Imaging GmbH;   CERES GmbH
Recruiting - verified September 2016

Dexmedetomidine Effect on Mitochondrial Function

Conditions:   Complication of Anesthesia;   Ischaemia-reperfusion Injury
Interventions:   Drug: Dexmedetomidine;   Drug: 0.9% NaCl
Sponsor:   The Hospital for Sick Children
Active, not recruiting - verified September 2016

Longterm Outcome After Ventricular Septal Defect Closure

Condition:   Ventricular Septal Defect
Interventions:   Other: MRI exercise test;   Other: Gas-exchange exercise test
Sponsor:   University of Aarhus
Completed - verified September 2016

Study of Smith-Lemli-Opitz Syndrome

Conditions:   Abnormalities;   Inborn Errors of Metabolism;   Mental Retardation;   Muscle Hypotonia;   Smith Lemli Opitz Syndrome
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified September 2016

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