Congenital Heart Defects

Clinical Trial Finder

Many patients with congenital heart defects are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Congenital Heart Disease GEnetic NEtwork Study (CHD GENES)

Condition:   Congenital Heart Defects
Sponsors:   Children's Hospital Medical Center, Cincinnati;   National Heart, Lung, and Blood Institute (NHLBI)

Impact of Serious Pediatric Illness on Parent and Sibling Health

Conditions:   Family Members of: Newborns Extremely Premature;   Family Members of: New Pediatric Oncology Patients;   Family Members of: Critical Congenital Heart Defect Patients;   Family Members of: Children Severe Neurological Impairment
Sponsors:   Children's Hospital of Philadelphia;   Cigna Foundation
Enrolling by invitation

gNO During CPB in Neonates to Reduce Risk of AKI

Conditions:   AKI;   CHD - Congenital Heart Disease;   Surgery
Interventions:   Drug: Nitric Oxide;   Drug: Oxygen
Sponsors:   Children's Hospital Medical Center, Cincinnati;   Mallinckrodt;   Indiana University

Identification of Genes Expressed in Atherosclerotic Plaque

Condition:   Atherosclerosis
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)

Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome

Conditions:   DiGeorge Syndrome;   22q11.2 Deletion Syndrome
Sponsors:   Albert Einstein College of Medicine;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting

Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study

Conditions:   Congenital Heart Defect;   Executive Function;   Children;   Neurodevelopmental Disorders;   Working Memory;   Infant Open Heart Surgery
Intervention:   Behavioral: Cogmed Working Memory Training
Sponsors:   Boston Children’s Hospital;   United States Department of Defense
Active, not recruiting

Quantitative Detection of Circulating Donor-Specific DNA in Organ Transplant Recipients (DTRT-Multi-Center Study)

Conditions:   Cardiovascular Disease;   Acute Rejection of Cardiac Transplant;   Cardiac Transplant Rejection;   Heart Transplant Failure and Rejection
Intervention:   Diagnostic Test: Blood Draw of up to 10 ml
Sponsors:   Medical College of Wisconsin;   National Heart, Lung, and Blood Institute (NHLBI);   Columbia University;   Duke University;   Arkansas Children's Hospital Research Institute;   Emory University;   Children's Healthcare of Atlanta;   Vanderbilt University;   TAI Diagnostics, Inc.;   Ann & Robert H. Lurie Children's Hospital Chicago;   Children's Hospital and Health System Foundation, Wisconsin
Active, not recruiting

Triac Trial II in MCT8 Deficiency Patients

Condition:   Allan-Herndon-Dudley Syndrome
Intervention:   Drug: Triac
Sponsors:   Rare Thyroid Therapeutics International AB;   Erasmus Medical Center
Not yet recruiting