Cardiomyopathy

Clinical Trial Finder

Many patients with cardiomyopathy are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

Conditions:   Cardiomyopathy, Hypertrophic;   Cardiomyopathy, Hypertrophic, Familial
Intervention:   Drug: Perhexiline
Sponsor:   Heart Metabolics Limited
Recruiting - verified August 2016

Determination of Left Ventricular Ejection Fraction Using Cardiac Angioscintigraphy

Conditions:   Angioscintigraphy;   Tomoscintigraphy
Interventions:   Drug: stannous pyrophosphate;   Drug: Technetium-99m;   Device: E-CAM Camera;   Device: CZT Semiconductor Camera (D-SPECT)
Sponsor:   Central Hospital, Nancy, France
Recruiting - verified August 2016

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Condition:   Transthyretin (TTR) Amyloid Cardiomyopathy
Intervention:   Drug: Tafamidis meglumine
Sponsor:   Pfizer
Recruiting - verified August 2016

Employing End Tidal Capnography in Continuous Flow Ventricular Assist Device Patients

Conditions:   Cardiomyopathy;   Cardiovascular Disease;   Heart Disease
Interventions:   Device: Respiratory Depression Monitoring with End Tidal Carbon Dioxide Nasal Cannula (ETCO2- NC);   Other: Standard Non-invasive Respiratory Depression Monitoring
Sponsor:   Emory University
Not yet recruiting - verified August 2016

Influence of Severe Heart Failure to Function and Molecular Biological Parameters of Catabolism in the Human Diaphragm and Peripheral Skeletal Muscle

Conditions:   Heart Failure;   Ischemic Myocardiopathy;   Dilatative Myocardiopathy
Interventions:   Other: Biopsy of the diaphragmatic muscle;   Other: Skeletal muscle biopsy
Sponsor:   Norman Mangner
Recruiting - verified August 2016

AiDing Diuresis wIth Tolvaptan (ADD-IT)

Conditions:   Cardiomyopathy;   Congestive Heart Failure
Interventions:   Drug: Tolvaptan 30 mg + IV Diuretics;   Drug: Metolazone 5 mg + IV Diuretics;   Drug: 2.5 times the Diuretics Dose
Sponsor:   Emory University
Recruiting - verified August 2016

Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR Imaging

Conditions:   Heart Failure;   Iron Overload;   Cardiomyopathies
Intervention:   Other: MR T2* imaging
Sponsor:   Chang Gung Memorial Hospital
Recruiting - verified August 2016

Stem Cell Injection in Cancer Survivors

Condition:   Cardiomyopathy Due to Anthracyclines
Interventions:   Biological: Allo-MSCs;   Biological: Placebo
Sponsors:   The University of Texas Health Science Center, Houston;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

Evaluation of Breathing, Sleep and the Effects of Continuous Positive Airway Pressure During Wakefulness in Children With Heart Failure

Condition:   Heart Failure
Interventions:   Other: Effect of CPAP on respiratory work and cardiac function indices during wakefulness;   Other: Effect of CPAP on respiratory work and cardiac function indices during wakefulness;   Other: Effect of CPAP on respiratory work and cardiac function indices during wakefulness;   Device: CPAP
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Philips Healthcare
Recruiting - verified August 2016

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Eleclazine;   Drug: Placebo
Sponsor:   Gilead Sciences
Recruiting - verified August 2016

Immunity Against AAV in Crigler Najjar Patient

Condition:   Crigler Najjar Syndrome
Intervention:   Biological: Blood sample for immunology
Sponsor:   Genethon
Recruiting - verified August 2016

A Randomized Study of the Efficacy of a New Intervention for Medication Adherence in Chronic Illness: Medications, Meaning and Me (The 3-M Study)

Condition:   Self-management in Heart Failure
Interventions:   Behavioral: CHIME 3-M;   Behavioral: attention control
Sponsors:   Duke University;   National Institute of Nursing Research (NINR)
Completed - verified October 2014

MOMENTUM 3 IDE Clinical Study Protocol

Condition:   Advanced Refractory Left Ventricular Heart Failure
Interventions:   Device: HeartMate 3 LVAS;   Device: HeartMate II LVAS
Sponsors:   Thoratec Corporation;   St. Jude Medical
Active, not recruiting - verified August 2016

Therapeutic Approach to Diastolic Dysfunction in Chronic Liver Disease Patients and Its Impact on Morbidity and Mortality

Conditions:   Diastolic Dysfunction;   Chronic Liver Disease
Interventions:   Drug: Carvedilol;   Drug: Ivabradine;   Procedure: Endoscopic Variceal Ligation
Sponsor:   Institute of Liver and Biliary Sciences, India
Completed - verified February 2016

Evaluation of G-CSF (Colony Stimulating Factor) in Patients With Chronic Chagas Cardiomyopathy

Condition:   Chronic Chagasic Myocarditis
Interventions:   Drug: Treatment with G-CSF (Granulocyte colony stimulating factor);   Drug: Placebo saline
Sponsor:   Hospital Sao Rafael
Enrolling by invitation - verified August 2016

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

Conditions:   Cardiomyopathy;   Coronary Artery Disease;   Congestive Heart Failure;   Myocardial Infarction
Interventions:   Device: Implantable Cardioverter Defibrillator;   Other: Optimal Medical Therapy
Sponsor:   VA Office of Research and Development
Recruiting - verified August 2016

CRT Implant Strategy Using the Longest Electrical Delay for Non-left Bundle Branch Block Patients

Conditions:   Non-left Bundle Branch Block;   Ischemic or Non-ischemic Cardiomyopathy
Interventions:   Other: QLV based implant strategy;   Other: Standard of care implant strategy
Sponsor:   St. Jude Medical
Enrolling by invitation - verified August 2016

A Biomarker and MRI Study on Troponin Release After Exercise in Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Intervention:  
Sponsor:   Heartcenter, University Medical Center St. Radboud
Active, not recruiting - verified August 2016

The SMARTEX Heart Failure Study

Condition:   Heart Failure
Interventions:   Behavioral: Aerobic Interval Training;   Behavioral: Moderate continues training;   Behavioral: Recommendation of regular moderate exercise
Sponsors:   Norwegian University of Science and Technology;   University Hospital, Antwerp;   UMC Utrecht;   Technische Universität München;   Heartcenter Leipzig GmbH;   Bispebjerg Hospital;   St. Olavs Hospital;   Helse Stavanger HF
Completed - verified August 2016

Measuring Electrical Resistance of Different Tissues on the Outer Surface of the Heart

Conditions:   Cardiomyopathies;   Ventricular Dysfunction;   Myocardial Infarction;   Arrhythmia
Intervention:  
Sponsors:   University of Pennsylvania;   Biosense Webster, Inc.
Terminated - verified August 2016

Genetics of Cardiovascular and Neuromuscular Disease

Conditions:   Cardiomyopathy;   Arrhythmia;   Muscular Dystrophy
Intervention:   Procedure: Blood draw (genetic testing)
Sponsor:   University of Chicago
Recruiting - verified August 2016