Cardiomyopathy

Clinical Trial Finder

Many patients with cardiomyopathy are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Conditions:   Mild Tricuspid Regurgitation;   Moderate Tricuspid Regurgitation;   Tricuspid Regurgitation
Interventions:   Procedure: TV Annuloplasty;   Procedure: MVS Alone
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   German Society for Thoracic and Cardiovascular Surgery
Not yet recruiting - verified February 2016

An Exploratory Study of 18F-Labeled Hydroxyphenethylguanidines in Heart Failure Patients

Condition:   Cardiomyopathy
Interventions:   Drug: [18F]4F-MHPG;   Drug: [18F]3F-PHPG;   Drug: [13N]ammonia;   Drug: [11C]HED
Sponsor:   University of Michigan
Recruiting - verified January 2016

Influence of Severe Heart Failure to Function and Molecular Biological Parameters of Catabolism in the Human Diaphragm and Peripheral Skeletal Muscle

Conditions:   Heart Failure;   Ischemic Myocardiopathy;   Dilatative Myocardiopathy
Interventions:   Other: Biopsy of the diaphragmatic muscle;   Other: Skeletal muscle biopsy
Sponsor:   Norman Mangner
Recruiting - verified January 2016

Clinical Research to Explore Manifestations of Heart Failure Using Infrared Thermal Imaging Technology

Condition:   Heart Failure,Congestive
Intervention:  
Sponsor:   Jing Huang
Recruiting - verified February 2016

Mobilization of Endothelial Progenitor Cells and Aspirin

Condition:   Hypertrophic Obstructive Cardiomyopathy
Intervention:   Drug: Aspirin
Sponsor:   Ottawa Heart Institute Research Corporation
Not yet recruiting - verified January 2016

Effects of Levosimendan and Milrinone on Left and Right Ventricular Function in Septic Cardiomyopathy

Conditions:   Septic Shock;   Cardiomyopathy
Interventions:   Drug: Levosimendan;   Drug: Milrinone
Sponsor:   Sahlgrenska University Hospital, Sweden
Recruiting - verified December 2015

Fatty Acid Oxidation Defects and Insulin Sensitivity

Conditions:   Very Long-chain Acyl-CoA Dehydrogenase Deficiency;   Trifunctional Protein Deficiency;   Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency;   Medium-chain Acyl-CoA Dehydrogenase Deficiency;   Normal Volunteers
Interventions:   Drug: Intralipid/Heparin;   Drug: Glycerol/Saline;   Drug: Hyperinsulinemic euglycemic clamp
Sponsor:   Oregon Health and Science University
Recruiting - verified February 2016

A Long-Term Extension Study of RP103-MITO-001 to Assess RP103 in Children With Inherited Mitochondrial Disease

Condition:   Mitochondrial Diseases
Intervention:   Drug: Cysteamine Bitartrate Delayed-release Capsules
Sponsor:   Raptor Pharmaceuticals Inc.
Enrolling by invitation - verified June 2015

Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients

Conditions:   Heart Failure;   Cardiomyopathy;   Ventricular Dysfunction
Interventions:   Biological: MPC Intramyocardial Injection;   Drug: Control Solution
Sponsors:   Annetine Gelijns;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 2016

A Rollover Study of ARRY-371797 in Patients With LMNA-Related Dilated Cardiomyopathy

Condition:   LMNA-Related Dilated Cardiomyopathy
Intervention:   Drug: ARRY-371797, p38 inhibitor, oral
Sponsor:   Array BioPharma
Recruiting - verified February 2016

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Eleclazine;   Drug: Placebo
Sponsor:   Gilead Sciences
Recruiting - verified January 2016

Budapest Upgrade CRT Study (Version 009-4)

Condition:   Cardiomyopathy
Intervention:   Device: CRT-D
Sponsors:   Semmelweis University Heart and Vascular Center;   University of Rochester;   Sheba Medical Center;   Pharmahungary Group
Enrolling by invitation - verified February 2016

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System

Condition:   Mitral Valve Regurgitation
Intervention:   Device: Mitral valve replacement
Sponsor:   Neovasc Inc.
Recruiting - verified January 2016

Arrhythmia Prediction Trial

Conditions:   Myocardial Infarction;   Dilated Cardiomyopathy;   Heart Failure
Intervention:  
Sponsor:   University of Athens
Recruiting - verified January 2016

Remote Ischemic Preconditioning With Postconditioning in Heart Transplantation Surgery

Conditions:   Myocardial Ischemic Reperfusion Injury;   End Stage Heart Disease;   Heart Failure;   Cardiomyopathy
Interventions:   Procedure: RIPC+RIPostC;   Procedure: control
Sponsor:   Chinese Academy of Medical Sciences, Fuwai Hospital
Recruiting - verified February 2016

Renal Denervation In Patient Undergoing VT Ablation:Combined Renal Denervation and VT Ablation vs. Simply VT Ablation

Conditions:   Ventricular Tachycardia;   Cardiomyopathy
Interventions:   Procedure: Ablation of ventricular arrhythmias;   Procedure: Ablation of ventricular arrhythmias + renal denervation
Sponsors:   Universitätsklinikum Hamburg-Eppendorf;   Medtronic
Terminated - verified February 2016

Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3)

Conditions:   Cardiomyopathy;   Renal Impairment
Interventions:   Drug: Tadalafil;   Drug: Placebo
Sponsor:   Mayo Clinic
Recruiting - verified January 2016

Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial Disease

Condition:   Inherited Mitochondrial Disease, Including Leigh Syndrome
Intervention:   Drug: Cysteamine Bitartrate Delayed-release Capsules (RP103)
Sponsor:   Raptor Pharmaceuticals Inc.
Enrolling by invitation - verified June 2015

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy

Condition:   Transthyretin (TTR) Amyloid Cardiomyopathy
Interventions:   Drug: Tafamidis;   Drug: Tafamidis;   Drug: Placebo
Sponsor:   Pfizer
Active, not recruiting - verified February 2016

Cardiac Magnetic Resonance GUIDEd Management of Mild-moderate Left Ventricular Systolic Dysfunction.

Conditions:   Heart Failure;   Left Ventricular Systolic Dysfunction
Interventions:   Device: ICD;   Device: ILR
Sponsors:   Flinders University;   South Australian Health and Medical Research Institute
Recruiting - verified February 2016

The Effects of Ranolazine on CPET Parameters in Ischemic Cardiomyopathy Patients (ERIC)

Condition:   Cardiomyopathy
Intervention:   Drug: Ranolazine
Sponsors:   Cardiovascular Institute of the South Clinical Research Corporation;   Gilead Sciences
Recruiting - verified January 2016

Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy

Conditions:   Apical Ballooning Syndrome;   Nervous System Diseases, Sympathetic
Interventions:   Drug: Placebo;   Drug: alpha-lipoic acid;   Drug: L-acetyl carnitine
Sponsor:   Second University of Naples
Completed - verified January 2016

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

Conditions:   Inflammation;   Cancer;   Cardiomyopathy
Intervention:  
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Enrolling by invitation - verified September 2015

Transthyretin-Associated Amyloidoses Outcome Survey (THAOS)

Conditions:   Transthyretin Mutations;   Transthyretin Amyloidosis
Intervention:   Other: None. Observational Study.
Sponsor:   Pfizer
Recruiting - verified February 2016