Cardiomyopathy

Clinical Trial Finder

Many patients with cardiomyopathy are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

99mTc-rhAnnexin V-128 Imaging and Cardiotoxicity in Patients With Early Breast Cancer

Conditions:   Breast Cancer;   Doxorubicin Induced Cardiomyopathy
Intervention:   Radiation: 99mTc-rhAnnexin V-128
Sponsor:   Advanced Accelerator Applications
Not yet recruiting - verified February 2016

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Conditions:   Mild Tricuspid Regurgitation;   Moderate Tricuspid Regurgitation;   Tricuspid Regurgitation
Interventions:   Procedure: TV Annuloplasty;   Procedure: MVS Alone
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   German Society for Thoracic and Cardiovascular Surgery
Not yet recruiting - verified February 2016

An Exploratory Study of 18F-Labeled Hydroxyphenethylguanidines in Heart Failure Patients

Condition:   Cardiomyopathy
Interventions:   Drug: [18F]4F-MHPG;   Drug: [18F]3F-PHPG;   Drug: [13N]ammonia;   Drug: [11C]HED
Sponsor:   University of Michigan
Recruiting - verified January 2016

Influence of Severe Heart Failure to Function and Molecular Biological Parameters of Catabolism in the Human Diaphragm and Peripheral Skeletal Muscle

Conditions:   Heart Failure;   Ischemic Myocardiopathy;   Dilatative Myocardiopathy
Interventions:   Other: Biopsy of the diaphragmatic muscle;   Other: Skeletal muscle biopsy
Sponsor:   Norman Mangner
Recruiting - verified January 2016

Clinical Research to Explore Manifestations of Heart Failure Using Infrared Thermal Imaging Technology

Condition:   Heart Failure,Congestive
Intervention:  
Sponsor:   Jing Huang
Recruiting - verified February 2016

Mobilization of Endothelial Progenitor Cells and Aspirin

Condition:   Hypertrophic Obstructive Cardiomyopathy
Intervention:   Drug: Aspirin
Sponsor:   Ottawa Heart Institute Research Corporation
Not yet recruiting - verified January 2016

Effects of Levosimendan and Milrinone on Left and Right Ventricular Function in Septic Cardiomyopathy

Conditions:   Septic Shock;   Cardiomyopathy
Interventions:   Drug: Levosimendan;   Drug: Milrinone
Sponsor:   Sahlgrenska University Hospital, Sweden
Recruiting - verified December 2015

Fatty Acid Oxidation Defects and Insulin Sensitivity

Conditions:   Very Long-chain Acyl-CoA Dehydrogenase Deficiency;   Trifunctional Protein Deficiency;   Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency;   Medium-chain Acyl-CoA Dehydrogenase Deficiency;   Normal Volunteers
Interventions:   Drug: Intralipid/Heparin;   Drug: Glycerol/Saline;   Drug: Hyperinsulinemic euglycemic clamp
Sponsor:   Oregon Health and Science University
Recruiting - verified February 2016

A Long-Term Extension Study of RP103-MITO-001 to Assess RP103 in Children With Inherited Mitochondrial Disease

Condition:   Mitochondrial Diseases
Intervention:   Drug: Cysteamine Bitartrate Delayed-release Capsules
Sponsor:   Raptor Pharmaceuticals Inc.
Enrolling by invitation - verified June 2015

Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients

Conditions:   Heart Failure;   Cardiomyopathy;   Ventricular Dysfunction
Interventions:   Biological: MPC Intramyocardial Injection;   Drug: Control Solution
Sponsors:   Annetine Gelijns;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 2016

A Rollover Study of ARRY-371797 in Patients With LMNA-Related Dilated Cardiomyopathy

Condition:   LMNA-Related Dilated Cardiomyopathy
Intervention:   Drug: ARRY-371797, p38 inhibitor, oral
Sponsor:   Array BioPharma
Recruiting - verified February 2016

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Eleclazine;   Drug: Placebo
Sponsor:   Gilead Sciences
Recruiting - verified January 2016

Budapest Upgrade CRT Study (Version 009-4)

Condition:   Cardiomyopathy
Intervention:   Device: CRT-D
Sponsors:   Semmelweis University Heart and Vascular Center;   University of Rochester;   Sheba Medical Center;   Pharmahungary Group
Enrolling by invitation - verified February 2016

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System

Condition:   Mitral Valve Regurgitation
Intervention:   Device: Mitral valve replacement
Sponsor:   Neovasc Inc.
Recruiting - verified January 2016

Arrhythmia Prediction Trial

Conditions:   Myocardial Infarction;   Dilated Cardiomyopathy;   Heart Failure
Intervention:  
Sponsor:   University of Athens
Recruiting - verified January 2016

Remote Ischemic Preconditioning With Postconditioning in Heart Transplantation Surgery

Conditions:   Myocardial Ischemic Reperfusion Injury;   End Stage Heart Disease;   Heart Failure;   Cardiomyopathy
Interventions:   Procedure: RIPC+RIPostC;   Procedure: control
Sponsor:   Chinese Academy of Medical Sciences, Fuwai Hospital
Recruiting - verified February 2016

Renal Denervation In Patient Undergoing VT Ablation:Combined Renal Denervation and VT Ablation vs. Simply VT Ablation

Conditions:   Ventricular Tachycardia;   Cardiomyopathy
Interventions:   Procedure: Ablation of ventricular arrhythmias;   Procedure: Ablation of ventricular arrhythmias + renal denervation
Sponsors:   Universitätsklinikum Hamburg-Eppendorf;   Medtronic
Terminated - verified February 2016

Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3)

Conditions:   Cardiomyopathy;   Renal Impairment
Interventions:   Drug: Tadalafil;   Drug: Placebo
Sponsor:   Mayo Clinic
Recruiting - verified January 2016

Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial Disease

Condition:   Inherited Mitochondrial Disease, Including Leigh Syndrome
Intervention:   Drug: Cysteamine Bitartrate Delayed-release Capsules (RP103)
Sponsor:   Raptor Pharmaceuticals Inc.
Enrolling by invitation - verified June 2015

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy

Condition:   Transthyretin (TTR) Amyloid Cardiomyopathy
Interventions:   Drug: Tafamidis;   Drug: Tafamidis;   Drug: Placebo
Sponsor:   Pfizer
Active, not recruiting - verified February 2016

Cardiac Magnetic Resonance GUIDEd Management of Mild-moderate Left Ventricular Systolic Dysfunction.

Conditions:   Heart Failure;   Left Ventricular Systolic Dysfunction
Interventions:   Device: ICD;   Device: ILR
Sponsors:   Flinders University;   South Australian Health and Medical Research Institute
Recruiting - verified February 2016

The Effects of Ranolazine on CPET Parameters in Ischemic Cardiomyopathy Patients (ERIC)

Condition:   Cardiomyopathy
Intervention:   Drug: Ranolazine
Sponsors:   Cardiovascular Institute of the South Clinical Research Corporation;   Gilead Sciences
Recruiting - verified January 2016

Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy

Conditions:   Apical Ballooning Syndrome;   Nervous System Diseases, Sympathetic
Interventions:   Drug: Placebo;   Drug: alpha-lipoic acid;   Drug: L-acetyl carnitine
Sponsor:   Second University of Naples
Completed - verified January 2016

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

Conditions:   Inflammation;   Cancer;   Cardiomyopathy
Intervention:  
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Enrolling by invitation - verified September 2015

Transthyretin-Associated Amyloidoses Outcome Survey (THAOS)

Conditions:   Transthyretin Mutations;   Transthyretin Amyloidosis
Intervention:   Other: None. Observational Study.
Sponsor:   Pfizer
Recruiting - verified February 2016

HIV-Associated Heart Disease

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Myocardial Diseases;   Acquired Immunodeficiency Syndrome;   HIV Infections
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified December 2001