Cardiomyopathy

Clinical Trial Finder

Many patients with cardiomyopathy are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Hypertrophic Cardiomyopathy Pilot Study

Conditions:   Hypertrophic Cardiomyopathy;   Coronary Artery Disease
Intervention:   Other: Observational: Arrhythmogenic Substrate
Sponsor:   Oregon Health and Science University
Not yet recruiting - verified June 2016

Molecular and Imaging Studies of Cardiovascular Health and Disease

Conditions:   Healthy;   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Ischemic Heart Disease
Interventions:   Other: Cardiovascular Magnetic Resonance;   Other: Fatmass measurement
Sponsor:   National Heart Centre Singapore
Recruiting - verified July 2013

Global CMR Registry

Condition:   Cardiovascular Diseases
Intervention:   Procedure: Cardiovascular Magnetic Resonance Imaging
Sponsor:   Society for Cardiovascular Magnetic Resonance
Active, not recruiting - verified June 2016

Biomarkers of Inherited Cardiovascular Conditions

Conditions:   Cardiomyopathy;   Ischemic Heart Disease
Intervention:   Other: Blood Sample Collection
Sponsor:   National Heart Centre Singapore
Recruiting - verified May 2016

Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC-TAVI Study

Conditions:   Severe and Symptomatic Aortic Stenosis;   Stable Coronary Disease
Intervention:   Procedure: TAVI procedure
Sponsor:   University Hospital, Montpellier
Not yet recruiting - verified June 2016

Carpal Tunnel Syndrome and Amyloid Cardiomyopathy

Conditions:   Amyloidosis;   Cardiomyopathy;   Transthyretin Amyloidosis;   Senile Systemic Amyloidosis;   Carpal Tunnel Syndrome
Intervention:  
Sponsor:   The Cleveland Clinic
Recruiting - verified April 2016

Pilot - Peri-operative Beta Blockade

Conditions:   Adrenergic Beta-Receptor Blockader;   Troponin Levels;   Cardiomyopathy, Post-surgical
Intervention:   Drug: metoprolol
Sponsor:   Washington University School of Medicine
Recruiting - verified June 2016

99mTc-rhAnnexin V-128 Imaging and Cardiotoxicity in Patients With Early Breast Cancer

Conditions:   Breast Cancer;   Doxorubicin Induced Cardiomyopathy
Intervention:   Radiation: 99mTc-rhAnnexin V-128
Sponsor:   Advanced Accelerator Applications
Active, not recruiting - verified June 2016

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Conditions:   Mild Tricuspid Regurgitation;   Moderate Tricuspid Regurgitation;   Tricuspid Regurgitation
Interventions:   Procedure: TV Annuloplasty;   Procedure: MVS Alone
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   German Society for Thoracic and Cardiovascular Surgery
Recruiting - verified June 2016

Molecular Imaging of Primary Amyloid Cardiomyopathy

Conditions:   Amyloidosis, Primary;   Cardiomyopathy
Interventions:   Radiation: F-18 florbetapir/C-11 acetate PET;   Device: MRI
Sponsors:   Brigham and Women's Hospital;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 2016

Safety and Performance of the Accucinch System

Conditions:   Heart Failure;   Mitral Valve Insufficiency
Intervention:   Device: Accucinch Implant
Sponsor:   Guided Delivery Systems Inc.
Not yet recruiting - verified June 2016

Added Value of Speckle Tracking in the Evaluation of Patients With Sickle Cell Disease

Condition:   Sickle Cell Disease
Interventions:   Other: Cardiac echography;   Other: Biological parameters;   Other: Clinical parameters
Sponsor:   Brugmann University Hospital
Recruiting - verified June 2016

Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC)

Conditions:   Dilated Cardiomyopathy (DCM);   Ischemic Cardiomyopathy;   Nonischemic Cardiomyopathy;   Heart Failure
Intervention:   Biological: Allogeneic Cardiosphere-Derived Cells (CDCs)
Sponsors:   Capricor Inc.;   Cedars-Sinai Medical Center;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified June 2016

Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease

Condition:   BRAF V600E Mutation
Interventions:   Drug: Dabrafenib Mesylate;   Drug: Trametinib Dimethyl Sulfoxide
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified April 2016

Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions

Conditions:   Neurodegenerative Diseases;   Osteoarthritis;   Erectile Dysfunction;   Autoimmune Diseases;   Cardiomyopathies;   Emphysema
Intervention:   Procedure: Administration of autologous adipose derived SVF
Sponsor:   Elliot Lander
Recruiting - verified June 2016

Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction

Condition:   Heart Failure With Preserved Ejection Fraction
Interventions:   Drug: LCZ696;   Drug: Valsartan
Sponsor:   Novartis Pharmaceuticals
Recruiting - verified June 2016

Nebivolol for the Prevention of Left Ventricular Systolic Dysfunction in Patients With Duchenne Muscular Dystrophy

Conditions:   Duchenne Muscular Dystrophy;   Cardiomyopathy;   Heart Failure
Interventions:   Drug: Nebivolol;   Drug: Placebo
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Association Française contre les Myopathies (AFM), Paris
Recruiting - verified June 2016

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

Condition:   TTR-CM
Intervention:   Drug: tafamidis
Sponsor:   Pfizer
Suspended - verified June 2016

Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases

Conditions:   Systemic Lupus Erythematosus;   Systemic Sclerosis
Intervention:   Procedure: Nonmyeloablative allogeneic stem cell transplant
Sponsor:   Duke University
Terminated - verified June 2016

Transthyretin-Associated Amyloidoses Outcome Survey (THAOS)

Conditions:   Transthyretin Mutations;   Transthyretin Amyloidosis
Intervention:   Other: None. Observational Study.
Sponsor:   Pfizer
Recruiting - verified June 2016

Efficacy of Implantable Cardioverter Defibrillator in Patients With Non-ischemic Systolic Heart Failure on Mortality

Conditions:   Heart Failure;   Dilated Cardiomyopathy;   Reduced LVEF
Interventions:   Device: ICD;   Other: Optimal medical treatment
Sponsors:   Danish Study Group;   Danish Heart Foundation
Active, not recruiting - verified June 2016