Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Ankle - Brachial Index Measurement in Atrial Fibrillation

Condition:   Atrial Fibrillation Fluttering
Intervention:   Device: ABI measurement using both doppler and oscillometric method
Sponsor:   Medical University of Warsaw
Completed - verified December 2016

Epicardial Fat Pads Ablation During Coronary Surgery

Conditions:   Atrial Fibrillation;   Ischemic Heart Disease
Interventions:   Procedure: Coronary artery bypass grafting;   Procedure: Epicardial ganglionated plexi ablation;   Procedure: implantable loop recorder
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified December 2016

The New Pharmaceutical Composition Containing Botulinum Toxin to Treat Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Ischemic Heart Disease
Interventions:   Drug: Pharmaceutical composition containing botulinum toxin;   Drug: 0.9% normal saline;   Procedure: Coronary artery bypass grafting
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified December 2016

Single Academic Center Experience in Atrial Fibrillation Patients Treated With OAC (CRAFT)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Medical University of Warsaw
Recruiting - verified December 2016

Dabigatran Versus Conventional Treatment for Prevention of Silent Cerebral Infarct in Atrial Fibrillation Associated With Valvular Disease

Conditions:   Atrial Fibrillation;   Valve Heart Disease
Interventions:   Drug: Dabigatran;   Drug: Acetylsalicylic acid;   Drug: Warfarin
Sponsors:   Asan Medical Center;   Boehringer Ingelheim
Not yet recruiting - verified December 2016

Treatment Pattern of Oral Anticoagulants (OAC) in Japan

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified December 2016

Left Atrial Appendage Occlusion and Biomarker Evaluation

Conditions:   Stroke;   Atrial Fibrillation;   Bleeding
Intervention:  
Sponsor:   Universitätsmedizin Mannheim
Recruiting - verified December 2016

ARENA - Project Atrial Fibrilation Rhine-Neckar Region

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Stiftung Institut fuer Herzinfarktforschung
Recruiting - verified November 2016

Maestro Handheld Cardiac Monitor Validation

Condition:   Cardiac Arrhythmia
Intervention:   Other: Maestro ECG
Sponsor:   University of Michigan
Recruiting - verified November 2016

Preventive Heart Rehabilitation to Prevent Complications in Patients Undergoing Elective Open Heart Surgery

Conditions:   Coronary (Artery); Disease;   Aortic Valve Stenosis;   Cardiac Surgery
Interventions:   Behavioral: Pre+post-operative Cardiac rehabilitation;   Behavioral: Postoperative Cardiac rehabilitation
Sponsor:   University Medical Center Groningen
Not yet recruiting - verified December 2016

Real-world Comparative Effectiveness of Stroke Prevention in Patients With Atrial Fibrillation Treated With Rivaroxaban vs. Vitamin k Antagonists

Condition:   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY597939);   Drug: Phenprocoumon (branded and generics)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Active, not recruiting - verified December 2016

Hybrid Catheter Ablation for Persistent Atrial Fibrillation

Condition:   Persistent Atrial Fibrillation
Interventions:   Procedure: hybrid catheter ablation;   Procedure: conventional endocardial ablation
Sponsor:   Korea University Anam Hospital
Recruiting - verified November 2016

AMPLATZER™ Amulet™ LAA Occluder Trial

Condition:   Stroke
Interventions:   Device: Amulet Left Atrial Appendage Occluder;   Device: WATCHMAN Left Atrial Appendage Closure
Sponsor:   St. Jude Medical
Recruiting - verified November 2016

Enhanced Detection of Underlying, Covert ATrial Fibrillation Using 7-day Holter Electrocardiogram in Patients With Embolic Stroke of Undetermined Source

Condition:   Stroke
Intervention:  
Sponsor:   National Cerebral and Cardiovascular Center
Recruiting - verified December 2016

Early Aggressive Invasive Intervention for Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Cryoballoon-based PVI;   Drug: Anti-Arrhythmic Drug Therapy
Sponsors:   Jason Andrade;   Ottawa Heart Institute Research Corporation
Not yet recruiting - verified November 2016

The Physiological Effects of Pacing on Catheter Ablation Procedures to Treat Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Pace During 1st Half of Lesion;   Procedure: Pace During 2nd Half of Lesion
Sponsor:   New York University School of Medicine
Recruiting - verified December 2016

Vimecon CAI Trial for the Interventional Treatment of Paroxysmal Atrial Fibrillation (AF)

Condition:   Atrial Fibrillation
Intervention:   Procedure: Vimecon Laser CAI percutaneous cardiac ablation
Sponsor:   Vimecon GmbH
Recruiting - verified December 2016

Stroke Lesion Pattern on MRI and Atrial Fibrillation

Conditions:   Stroke;   Atrial Fibrillation
Intervention:   Other: MRI
Sponsor:   Charite University, Berlin, Germany
Completed - verified December 2016

Improving Quality by Maintaining Accurate Problems in the EHR

Conditions:   Asthma;   Atrial Fibrillation;   Chronic Obstructive Pulmonary Disease;   Coronary Artery Disease;   Congestive Heart Failure;   Hyperlipidemia;   Hypertension;   Myocardial Infarction;   Sickle Cell Disease;   Sleep Apnea;   Smoking;   Stroke;   Tuberculosis
Intervention:   Other: Problem List Suggestion
Sponsors:   Brigham and Women's Hospital;   Geisinger Clinic;   Oregon Health and Science University;   Vanderbilt University
Active, not recruiting - verified December 2016

Rivaroxaban Utilization for Treatment and Prevention of Thromboembolism in Cancer Patients: Experience at a Comprehensive Cancer Center

Conditions:   Cancer;   Deep-vein Thrombosis of the Lower and Upper Extremities;   Pulmonary Embolism;   Non-valvular Atrial Fibrillation
Intervention:   Other: Retrospective Chart Review
Sponsors:   M.D. Anderson Cancer Center;   Janssen Scientific Affairs, LLC
Recruiting - verified December 2016

Elevate CLL R/R: Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Subjects With High Risk Chronic Lymphocytic Leukemia

Condition:   Chronic Lymphocytic Leukemia
Interventions:   Drug: ACP-196;   Drug: ibrutinib
Sponsor:   Acerta Pharma BV
Recruiting - verified November 2016

Impact of Best Practice Alerts in Cardiology Outpatient Clinics

Conditions:   Hypertension;   Atrial Fibrillation
Intervention:   Other: Best Practice Alert based in the Electronic Medical Record
Sponsor:   Duke University
Completed - verified November 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2016

A Genomic Approach to Warfarin Dose Prescription in Admixed Caribbean Hispanics

Conditions:   Atrial Fibrillation;   Deep Vein Thrombosis;   Cardiac Valvular Insufficiency;   Coagulopathies;   Pulmonary Embolism
Interventions:   Genetic: Genotype-guided;   Other: Standard-of-Care
Sponsors:   University of Puerto Rico;   National Institute on Minority Health and Health Disparities (NIMHD);   Genomas, Inc
Recruiting - verified November 2016

Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department

Condition:   Atrial Fibrillation
Interventions:   Drug: Pharmacological cardioversion - Flecainide;   Procedure: Electrical cardioversion;   Drug: Metoprolol;   Drug: Verapamil;   Drug: Digoxin;   Drug: Pharmacological cardioversion - Amiodarone
Sponsors:   Maastricht University Medical Center;   ZonMw: The Netherlands Organisation for Health Research and Development
Recruiting - verified July 2016

Efficacy, Safety and Efficiency of the nMARQ Pulmonary Vein Isolation System in Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: ablation
Sponsors:   Basildon and Thurrock University Hospitals NHS Foundation Trust;   Anglia Ruskin University
Active, not recruiting - verified December 2016

Right Ventricle (RV) Markers of Future Pacing Induced Ventricular Dysfunction - Pilot

Condition:   Sick Sinus Syndrome
Intervention:  
Sponsors:   Basildon and Thurrock University Hospitals NHS Foundation Trust;   Anglia Ruskin University
Completed - verified December 2016

Safety and Performance of a GLOBAL Mapping and Ablation Device for the Treatment of Atrial Fibrillation (GLOBAL-AF)

Condition:   Atrial Fibrillation
Intervention:   Device: Global mapping and ablation device
Sponsor:   Kardium Inc.
Recruiting - verified November 2016

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified October 2016

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Completed - verified June 2016

Eliquis Safety Surveillance in Japanese Patients With NonValvular Atrial Fibrillation

Condition:   NonValvular Atrial Fibrillation
Intervention:   Drug: Eliquis
Sponsors:   Bristol-Myers Squibb;   Pfizer
Active, not recruiting - verified January 2016

Essential Hypotension and Adaptability Registry

Conditions:   Blood Pressure;   Depression;   Panic Attack;   Fibromyalgia;   POTS;   Inappropriate Sinus Tachycardia;   Coronary Heart Disease;   Acute Coronary Syndrome (ACS);   Acute Myocardial Infarction (AMI);   Cerebrovascular Disease (CVD);   Transient Ischemic Attack (TIA);   Atrial Fibrillation;   Diabetes Mellitus;   Cancer;   Systolic Heart Failure;   Diastolic Heart Failure;   Chronic Fatigue Syndrome;   Syncope;   Vasovagal Syncope
Intervention:  
Sponsor:   CES University
Recruiting - verified November 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified December 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified December 2016

ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial

Condition:   End Stage Renal Failure on Dialysis
Interventions:   Drug: Spironolactone;   Drug: Placebo
Sponsors:   University Hospital, Brest;   Central Hospital, Nancy, France;   Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - verified November 2016

Evaluation of the Phased Radio Frequency Ablation System

Condition:   Persistent Atrial Fibrillation
Intervention:   Device: Medtronic Phased RF Ablation System
Sponsor:   Medtronic Atrial Fibrillation Solutions
Active, not recruiting - verified December 2016

Cryoballoon Pulmonary Venous Isolation in Patients Referred for Typical Atrial Flutter Ablation

Conditions:   Atrial Flutter;   Atrial Fibrillation
Interventions:   Procedure: Atrial flutter ablation;   Procedure: Atrial flutter ablation and pulmonary vein isolation
Sponsors:   University Hospital, Rouen;   Medtronic
Active, not recruiting - verified December 2016

A Machine Learning Approach to Continuous Vital Sign Data Analysis

Condition:   Vital Signs
Intervention:  
Sponsor:   University of Colorado, Denver
Enrolling by invitation - verified December 2016

Phase 2 Study of the Safety, Tolerability and Pilot Efficacy of Oral Factor Xa Inhibitor Betrixaban Compared to Warfarin

Condition:   Atrial Fibrillation
Interventions:   Drug: betrixaban;   Drug: Warfarin
Sponsor:   Portola Pharmaceuticals
Completed - verified November 2016

Atrial Fibrillation Management in Congestive Heart Failure With Ablation

Conditions:   Persistent Atrial Fibrillation;   Heart Failure;   ICD
Interventions:   Device: ICD/CRT implant;   Procedure: AF ablation;   Other: Best Medical Treatment
Sponsor:   St. Jude Medical
Active, not recruiting - verified November 2016

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