Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Comparison of Wide Area Circular Ablation With Extra-wide Area Circular Ablation in Subjects With Persistent Atrial Fibrillation, a Randomized Study

Condition:   Atrial Fibrillation
Intervention:   Procedure: Ablation
Sponsor:   Mosaic Life Care
Not yet recruiting - verified April 2016

Apixaban Dose Reduction in Patients With Elevated Drug Levels

Condition:   Atrial Fibrillation
Intervention:   Drug: apixaban dose reduction
Sponsors:   Hamilton Health Sciences Corporation;   Population Health Research Institute
Not yet recruiting - verified June 2016

Plasma Aldosterone Levels and Atrial Fibrillation Reduction (ALDO-AF Study)

Conditions:   Atrial Fibrillation;   Aldosterone
Intervention:  
Sponsor:   University Hospital, Caen
Recruiting - verified June 2016

The Effect of Chest Tubes Using Active Clearance Technology® on the Incidence of Postoperative Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Pericardial Effusion;   Pleural Effusion;   Hemothorax;   Cardiac Tamponade
Interventions:   Device: Standard drainage;   Device: Active Clearance Technology drainage
Sponsors:   Montreal Heart Institute;   ClearFlow, Inc.;   Hopital du Sacre-Coeur de Montreal
Recruiting - verified June 2016

Relationship Between Apelin and New-onset Atrial Fibrillation After Coronary Artery Bypass Grafting

Condition:   Coronary Atherosclerotic Heart Disease
Interventions:   Other: atrial fibrillation;   Other: non-atrial fibrillation
Sponsor:   General Hospital of Shenyang Military Region
Completed - verified June 2016

Predicting Development of SCAF in Device Patients

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Genome Canada
Not yet recruiting - verified June 2016

Study of DU-176b Aged 80 Years or Older

Condition:   Atrial Fibrillation
Interventions:   Drug: Du-176b;   Drug: placebo
Sponsor:   Daiichi Sankyo Co., Ltd.
Not yet recruiting - verified June 2016

Comparison of His Bundle Pacing and Bi-Ventricular Pacing in Heart Failure With Atrial Fibrillation

Conditions:   Heart Failure;   Atrial Fibrillation
Interventions:   Device: CRT Device and Bi-ventricular pacing;   Device: CRT Device and His-bundle Pacing
Sponsors:   First Affiliated Hospital of Wenzhou Medical Univeristy;   HT-Med Company;   Chinese Academy of Medical Sciences, Fuwai Hospital;   Shanghai Zhongshan Hospital;   Jiangsu People's Hospital;   Wuhan Asia Heart Hospital;   Sir Run Run Shaw Hospital;   Shanxi People's Hospital
Recruiting - verified June 2016

APixaban vs. PhenpRocoumon in Patients With ACS and AF: APPROACH-ACS-AF

Conditions:   Acute Coronary Syndrome;   Atrial Fibrillation;   Coronary Artery Disease
Interventions:   Other: Dual Therapy;   Other: Triple Therapy
Sponsors:   Klinikum der Universitaet Muenchen;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK);   Technische Universität München;   Helmholtz Zentrum München;   University of Göttingen;   University of München;   University Medicine Greifswald
Not yet recruiting - verified May 2016

Cryo AF Global Registry

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified June 2016

Catheter Ablation vs. Medical Therapy in Congested Hearts With AF

Conditions:   Congestive Heart Failure;   Left Ventricular Failure;   Atrial Fibrillation
Intervention:   Device: Catheter Ablation
Sponsors:   Oussama Wazni;   Biosense Webster, Inc.;   The Cleveland Clinic
Enrolling by invitation - verified June 2016

Isolation of Pulmonary Veins With the Aid of Magnetic Resonance Imaging

Condition:   Atrial Fibrillation
Interventions:   Procedure: Conventional AF ablation;   Procedure: LGE-MRI guided AF ablation
Sponsors:   Hospital Clinic of Barcelona;   Institut d'Investigacions Biomèdiques August Pi i Sunyer;   University of Barcelona
Recruiting - verified June 2016

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Conditions:   Mild Tricuspid Regurgitation;   Moderate Tricuspid Regurgitation;   Tricuspid Regurgitation
Interventions:   Procedure: TV Annuloplasty;   Procedure: MVS Alone
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   German Society for Thoracic and Cardiovascular Surgery
Recruiting - verified June 2016

Quality of Anticoagulation With Warfarin in Patient With Atrial Fibrillation for Secondary Stroke Prevention in Korea

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Inje University
Recruiting - verified June 2016

A Comparator Trial on the Relative Efficacy of Two Triglyceride Forms of Fish Oil

Condition:   Healthy Volunteers
Interventions:   Dietary Supplement: Fish Oil;   Dietary Supplement: Fish Oil
Sponsors:   Nordic Pharma, USA;   Nutrasource Diagnostics Inc.
Active, not recruiting - verified June 2016

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Exercise Training in Patients With Atrial Fibrillation (OPPORTUNITY Study)

Condition:   Atrial Fibrillation
Interventions:   Behavioral: moderate-intensity continuous exercise training;   Behavioral: high-intensity interval training
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting - verified June 2016

Patient Convenience Study

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Anticoagulation Preference by AF Patients Study

Condition:   Atrial Fibrillation
Interventions:   Other: VKAs;   Other: NOACs including Rivaroxaban (Xarelto, BAY59-7939);   Other: Edoxaban;   Other: Apixaban;   Other: Dabigatran-etexilate
Sponsor:   Bayer
Recruiting - verified June 2016

Real Evidence of Anticoagulation Treatment in Non-valvular Atrial Fibrillation in Germany and the UK: REACT-AF2

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Bristol-Myers Squibb;   IMS Health;   Oxon Epidemiology
Active, not recruiting - verified June 2016

Elevate CLL R/R: Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Subjects With High Risk Chronic Lymphocytic Leukemia

Condition:   Chronic Lymphocytic Leukemia
Interventions:   Drug: ACP-196;   Drug: ibrutinib
Sponsor:   Acerta Pharma BV
Recruiting - verified June 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified May 2016

Antithrombotic Strategy Variability In ATrial Fibrillation and Obstructive Coronary Disease Revascularized With PCI - The AVIATOR 2 Registry

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Icahn School of Medicine at Mount Sinai;   Bristol-Myers Squibb
Recruiting - verified June 2016

Reduction of AF Ablation Induced Thrombo-Embolic Incidence Pilot Study

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Device: Cerebral Diffusion-Weighted Magnetic Resonance Imaging;   Device: Transesophageal Echocardiography;   Other: Paperbased neurocognitive testing
Sponsors:   Biotronik SE & Co. KG;   University Hospital Heidelberg
Recruiting - verified June 2016

Rate Control in Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Drug: Carvedilol;   Drug: Metoprolol tartrate
Sponsor:   Creighton University
Not yet recruiting - verified June 2016

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:   Device: Reveal LINQ Insertable Cardiac Monitor
Sponsor:   Northwell Health
Recruiting - verified June 2016

Left-Atrium-Appendage Occluder Register - GErmany

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Stiftung Institut fuer Herzinfarktforschung
Active, not recruiting - verified June 2016

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Atrial Fibrillation Detected by ELR and Holter Recording, a Comparison in Patients With Ischemic Stroke or TIA

Conditions:   Stroke;   Ischaemic Stroke;   Atrial Fibrillation;   Supra Ventricular Extra Systoles
Intervention:  
Sponsors:   University of Aarhus;   Hospitalsenheden Vest
Recruiting - verified June 2016

Augmented Wide Area Circumferential Catheter Ablation for Reduction of Atrial Fibrillation Recurrence

Condition:   Atrial Fibrillation
Interventions:   Procedure: Wide area circumferential catheter ablation;   Procedure: Augmented- wide area circumferential ablation procedure
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting - verified June 2016

Vasoactive Drugs in Intensive Care Unit

Condition:   Shock
Interventions:   Drug: Norepinephrine;   Drug: Epinephrine;   Drug: Phenylephrine;   Drug: Vasopressin
Sponsor:   University of Chicago
Recruiting - verified May 2016

FIRM as a Stand-alone Procedure in the Treatment of Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Procedure: FIRM ablation
Sponsor:   Oslo University Hospital
Completed - verified June 2016

Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Hypertension
Interventions:   Drug: Renal nerve denervation;   Device: Cryoablation
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified June 2016

Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer

Conditions:   Rivaroxaban;   Cancer-associated Thrombosis;   Recurrence;   Bleeding
Intervention:   Drug: Rivaroxaban
Sponsors:   Seoul National University Hospital;   Korean Society of Hematology Thrombosis Working Party
Active, not recruiting - verified June 2016

Intensive Statin Therapy Effect on Post-Operative Atrial Fibrillation (POAF)

Conditions:   Cardiothoracic Surgery;   Post-operative Atrial Fibrillation
Interventions:   Drug: Atorvastatin 20 mg;   Drug: Atorvastatin 80 mg
Sponsor:   Creighton University
Recruiting - verified June 2016

Ablation of Complex Fractionated Electrograms With or Without Additional Linear Lesions for Persistent Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Recurrence
Interventions:   Procedure: PVI+CFAE+DCC;   Procedure: PVI, CFAE, anterior and roof line, DCC
Sponsor:   Deutsches Herzzentrum Muenchen
Completed - verified June 2016

Anticoagulant Utilization Pattern

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa (Dabigatran etexilate mesilate)
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Stroke Prevention and Rhythm Interventions in Atrial Fibrillation

Condition:   Cardiovascular Diseases
Intervention:  
Sponsors:   Canadian Cardiovascular Research Network;   Bayer
Active, not recruiting - verified June 2016

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II)

Condition:   Atrial Fibrillation
Intervention:   Other: Patients with Atrial Fibrillation
Sponsors:   Janssen Scientific Affairs, LLC;   Duke Clinical Research Institute
Recruiting - verified June 2016

Evaluation of the Phased Radio Frequency Ablation System

Condition:   Persistent Atrial Fibrillation
Intervention:   Device: Medtronic Phased RF Ablation System
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified June 2016

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2016

Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia

Conditions:   AtrioVentricular Nodal Reentrant Tachycardia;   Supraventricular Tachycardia;   Heart Disease
Intervention:   Device: Freezor Xtra Cryoablation Catheter
Sponsor:   Medtronic Atrial Fibrillation Solutions
Active, not recruiting - verified June 2016

FREEZE Cohort Study

Condition:   Arrhythmia
Intervention:  
Sponsors:   Stiftung Institut fuer Herzinfarktforschung;   Medtronic
Active, not recruiting - verified June 2016

Interventional Strategies in Treatment of Atrial Fibrillation: Percutaneous Closure of the Left Atrial Appendage Versus Catheter Ablation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Percutaneous closure of LAA;   Procedure: Catheter ablation of AF
Sponsor:   Deutsches Herzzentrum Muenchen
Completed - verified June 2016

Ablating Atrial Tachycardias Occuring During Ablation of Complex Fractionated Electrograms in Persistent AF

Conditions:   Atrial Fibrillation;   Ablation;   Atrial Flutter
Interventions:   Procedure: Ablation;   Procedure: Cardioversion
Sponsors:   Deutsches Herzzentrum Muenchen;   Klinik für Kardiologie, Klinikum Karlsruhe, Prof. Dr. C. Schmitt
Completed - verified June 2016

Low Versus High Dose Magnesium Sulfate in the Early Management of Rapid Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Drug: Magnesium Sulfate high dose;   Drug: Magnesium Sulfate low dose
Sponsor:   University of Monastir
Completed - verified June 2016

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