Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Clinical and Economic Outcomes of Oral Anticoagulants in Non-valvular Atrial Fibrillation

Condition:   Non-Valvular Atrial Fibrillation
Intervention:  
Sponsor:   Bristol-Myers Squibb
Active, not recruiting - verified March 2017

Computer Simulated Atrial Fibrillation Tool

Condition:   Atrial Fibrillation
Intervention:   Other: Virtual Platform
Sponsors:   Nova Scotia Health Authority;   Cardiac Arrhythmia Network of Canada
Not yet recruiting - verified March 2017

Estimation of Average and Beat-to-beat Heart Rate With a Novel Wrist-worn PPG Device in Surgery Patients

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Tampere University Hospital;   PulseOn Ltd
Not yet recruiting - verified March 2017

A Pilot Study of Edoxaban in Patients With Non-Valvular Atrial Fibrillation and Left Atrial Appendage Closure

Conditions:   Non-Valvular Atrial Fibrillation;   Left Atrial Appendage Closure
Interventions:   Drug: Edoxaban;   Device: WATCHMAN LAA Closure;   Drug: Aspirin and Clopidogrel;   Drug: Aspirin and Warfarin
Sponsors:   Scripps Health;   Daiichi Sankyo Inc.
Not yet recruiting - verified March 2017

NATional TUnisian REgistry of Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Dacima Consulting;   Société Tunisienne de Cardiologie & de Chirurgie Cardio-Vasculaire
Recruiting - verified March 2017

Mapping Electrogram Morphology Recurrence for Atrial Fibrillation Ablation

Condition:   Atrial Fibrillation
Intervention:   Device: Electrogram Morphology Mapping (EMR)
Sponsors:   Jeffrey Goldberger;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified February 2017

Repetitive Activation Patterns and Focal Impulses Identification and Ablation in Persistent AF

Condition:   Persistent Atrial Fibrillation (AF)
Intervention:   Procedure: cartofinder guided ablation followed by PVI
Sponsor:   Biosense Webster, Inc.
Recruiting - verified March 2017

Effect of Antithrombotic Treatment in Patients With Both Coronary Heart Disease and Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Coronary Heart Disease
Intervention:  
Sponsor:   Henan Institute of Cardiovascular Epidemiology
Recruiting - verified March 2017

TOnicity of Perioperative Maintenance SoluTions

Conditions:   Thoracic Diseases;   Water-Electrolyte Imbalance;   Fluid Overload;   Fluid Retention;   Sodium Disorder;   Potassium Disorders;   Chloride Disorder
Interventions:   Drug: NaCl 0.9% in Glucose 5% + 40mmol/L Potassium;   Drug: Glucion 5%
Sponsor:   Niels Van Regenmortel
Recruiting - verified March 2017

A Study to Evaluate the Safety and Effectiveness of the Left Atrial Appendage Closure Therapy Using BSJ003W

Condition:   Atrial Fibrillation Non-Rheumatic
Intervention:   Device: BSJ003W
Sponsor:   Boston Scientific Japan K.K.
Recruiting - verified March 2017

STOP Persistent AF

Condition:   Atrial Fibrillation
Intervention:   Device: Arctic Front Advance Cardiac CryoAblation Catheter
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified March 2017

Comparison of Left Atrial Appendage Occlusion vs Standard Medical Therapy in Patients in AF Undergoing TAVI

Conditions:   Atrial Fibrillation;   Aortic Stenosis
Intervention:   Device: LAAO
Sponsors:   University of Zurich;   St. Jude Medical
Recruiting - verified March 2017

Opportunistic Screening in Pharmacies for Atrial Fibrillation in Seniors (>65 Years)

Condition:   Incidence of Atrial Fibrillation in Adults Aged ≥ 65
Intervention:  
Sponsors:   RWTH Aachen University;   Apothekerverband Aachen e.V.;   Pfizer
Active, not recruiting - verified March 2017

Enhanced Diagnostics for Early Detection of Atrial Fibrillation - Prospective Validation

Conditions:   Atrium; Fibrillation;   Arrhythmia Atrial
Intervention:   Device: Five minutes puls wave recording
Sponsors:   University Hospital, Basel, Switzerland;   University Hospital Greifswald
Recruiting - verified March 2017

Identification, Electro-mechanical Characterisation and Ablation of Driver Regions in Persistent Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Other: Novel mapping algorithm
Sponsor:   Barts & The London NHS Trust
Recruiting - verified March 2017

Impact of Left Atrial Appendage Closure on Physical Capacity.

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   University of Leipzig;   University of Jena
Recruiting - verified March 2017

Impact of Implantation of an LAA Occluder on ANP and BNP Level and Quality of Life

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   University of Leipzig
Completed - verified March 2017

Rivaroxaban or Apixaban in Mechanical Valves: RAMV

Condition:   Thromboembolism
Interventions:   Drug: Rivaroxaban;   Drug: Apixaban 5 MG [Eliquis]
Sponsor:   Hospital Ana Nery
Available - verified March 2017

Xarelto Evidence in Real Life of Patients' Preference and Satisfaction Study

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified March 2017

Investigation of the Adagio PolarStar System in Patients With Paroxysmal Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Atrial Flutter
Intervention:   Device: PolarStar System
Sponsor:   Adagio Medical
Recruiting - verified March 2017

Effect of Remote Ischemic Preconditioning on Electrophysiological and Biomolecular Parameters in Non-valvular Paroxysmal Atrial Fibrillation: RIPPAF Study

Condition:   Atrial Fibrillation
Interventions:   Procedure: Remote ischemic preconditioning (RIPC);   Procedure: sham-intervention
Sponsor:   Jedrzej Kosiuk
Recruiting - verified March 2017

Patient Convenience Study- NIS RELATE

Condition:   Atrial Fibrillation
Interventions:   Drug: Pradaxa (dabigatran);   Drug: Vitamin K antagonist
Sponsor:   Boehringer Ingelheim
Recruiting - verified March 2017

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified March 2017

Cryo AF Global Registry

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified March 2017

Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting in Patients With Obstructive Sleep Apnea

Conditions:   Atrial Fibrillation;   Obstructive Sleep Apnea;   Coronary Artery Bypass Grafting
Intervention:   Device: CPAP
Sponsor:   Rodrigo Pinto Pedrosa
Recruiting - verified March 2017

On-pump Beating Coronary Artery Bypass Grafting by Ventricular Assist

Condition:   Coronary Artery Bypass
Interventions:   Device: left ventricular assist;   Procedure: Biventricular assist
Sponsor:   Henan Institute of Cardiovascular Epidemiology
Recruiting - verified January 2017

Impact of the Relaxation Response Resiliency Program on Patients With Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Stress;   Quality of Life;   Anxiety;   Depression;   Hostility
Intervention:   Behavioral: Relaxation Response Resiliency Program
Sponsors:   Massachusetts General Hospital;   Benson-Henry Institute for Mind Body Medicine
Recruiting - verified March 2017

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified March 2017

AF Patient Preference Study

Condition:   Atrial Fibrillation
Interventions:   Drug: VKA: Warfarin (Waran);   Drug: NOAC: Rivaroxaban (Xarelto, BAY59-7939);   Drug: NOAC: Dabigatran etexilate;   Drug: NOAC: Apixaban;   Drug: NOAC: Edoxaban;   Drug: NOAC: Lixiana
Sponsor:   Bayer
Completed - verified March 2017

Implantable Cardiac Monitors in High-Risk Post-Infarction Patients With Cardiac Autonomic Dysfunction

Conditions:   Myocardial Infarction;   Autonomic Nervous System Diseases
Intervention:   Device: Medtronic Reveal LINQ implantable cardiac monitor
Sponsors:   Klinikum der Universitaet Muenchen;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK);   Medtronic Bakken Research Center
Recruiting - verified March 2017

Edoxaban in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With Aspirin and Clopidogrel

Condition:   Coronary Artery Disease
Interventions:   Drug: Edoxaban 60 mg;   Drug: Edoxaban 30 mg;   Drug: Clopidogrel 75 mg;   Drug: Aspirin 81 mg
Sponsors:   University of Florida;   Daiichi Sankyo Inc.
Recruiting - verified March 2017

aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Device: LARIAT + PVI;   Device: Pulmonary Vein Isolation
Sponsor:   SentreHEART, Inc.
Recruiting - verified March 2017

Supervised Exercise Compared to PAP in Patients With Permanent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Other: Exercise;   Other: Physical activity
Sponsor:   Göteborg University
Recruiting - verified March 2017

Physiotherapist Led Group-exercise Compared Physical Activity on Prescription, a 3 Months Follow-up

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Göteborg University
Recruiting - verified March 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified March 2017

Rivaroxaban Versus Warfarin in the Evaluation of Progression of Coronary Calcium

Condition:   Atherosclerosis
Interventions:   Drug: rivaroxaban;   Drug: Warfarin
Sponsor:   Los Angeles Biomedical Research Institute
Recruiting - verified March 2017

Screening for Sleep Apnea in Patients Undergoing Atrial Fibrillation Ablation

Conditions:   Atrial Fibrillation;   Obstructive Sleep Apnea;   Cardiac Arrhythmias
Intervention:   Device: Home Sleep Testing Device
Sponsor:   Beth Israel Deaconess Medical Center
Recruiting - verified March 2017

Kyoto Congestive Heart Failure Study

Conditions:   Congestive Heart Failure;   Heart Failure, Diastolic;   Heart Failure, Systolic;   Elderly Frail;   Guideline Adherence
Intervention:   Other: Standard
Sponsor:   Kyoto University, Graduate School of Medicine
Recruiting - verified March 2017

Reduction of AF Ablation Induced Thrombo-Embolic Incidence Pilot Study

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Device: Cerebral Diffusion-Weighted Magnetic Resonance Imaging;   Device: Transesophageal Echocardiography;   Other: Paperbased neurocognitive testing
Sponsors:   Biotronik SE & Co. KG;   University Hospital Heidelberg
Terminated - verified March 2017

Measurement of Low-energy Stimulation in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Device: Multistage low-energy stimulation
Sponsor:   Cardialen, Inc.
Recruiting - verified March 2017

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified March 2017

Apixaban Versus Warfarin in the Evaluation of Progression of Atherosclerotic Calcification and Vulnerable Plaque

Condition:   Atrial Fibrillation
Interventions:   Drug: apixaban;   Drug: warfarin
Sponsor:   Los Angeles Biomedical Research Institute
Active, not recruiting - verified March 2017

Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure

Condition:   Current or Recent History of Atrial Fibrillation
Interventions:   Drug: bucindolol hydrochloride;   Drug: metoprolol succinate
Sponsors:   ARCA Biopharma, Inc.;   Medtronic
Recruiting - verified March 2017

Prevention of Atrial Fibrillation Following Valvular Replacement With Cardiopulmonary Bypass: a Prospective, Randomized Clinical Study Comparing Oral Caffeine With Placebo

Condition:   Atrial Fibrillation
Interventions:   Drug: citrate of caffeine;   Drug: placebo
Sponsor:   Assistance Publique Hopitaux De Marseille
Completed - verified August 2015

Renal Denervation Therapy in Hypertensive Patients Undergoing A-Fib Ablation

Conditions:   Atrial Fibrillation;   Hypertension
Interventions:   Procedure: AF ablation with Renal Denervation;   Procedure: AF ablation alone
Sponsor:   Siva Mulpuru
Terminated - verified March 2017

A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurrence

Conditions:   Persistent Atrial Fibrillation;   Paroxysmal Atrial Fibrillation;   Hypertension
Interventions:   Device: Renal Artery Ablation;   Device: Cardiac Ablation
Sponsor:   St. Jude Medical
Active, not recruiting - verified March 2017

Clinical Outcome of Pacemaker paTIents According to Pacing Modality and Primary INDications OPTI-MIND 2

Condition:   Bradyarrhythmia
Intervention:  
Sponsor:   Boston Scientific Corporation
Completed - verified February 2017

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified March 2017

Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defibrillators.

Conditions:   ICD;   Sudden Cardiac Death;   Ventricular Fibrillation;   Atrial Fibrillation;   Ventricular Tachycardia
Intervention:  
Sponsor:   Biotronik SE & Co. KG
Completed - verified March 2017

Cardiac Resynchronisation Therapy and AV Nodal Ablation Trial in Atrial Fibrillation Patients (CAAN-AF)

Conditions:   Heart Failure;   Atrial Fibrillation
Interventions:   Procedure: AV nodal ablation;   Drug: Medical Ventricular Rate Control
Sponsors:   University of Adelaide;   Medtronic;   St. Jude Medical;   Boston Scientific Corporation
Recruiting - verified March 2017

Ultrastructure of Atrial Myocytes in Patients in Sinus Rhythm and With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Norwegian University of Science and Technology
Completed - verified March 2017

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified March 2017

Manual Compared to Magnetic Navigation in Ablation for Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Magnetic navigation;   Procedure: Ablation performed with manual navigation
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital;   SINTEF Health Research
Completed - verified March 2017

Capsule Endoscopy for Post-Ablation Esophageal Lesion Assessment

Condition:   Esophageal Lesion
Intervention:   Diagnostic Test: PillCam ESO Capsule Endoscope
Sponsors:   The Cleveland Clinic;   Given Imaging Ltd.
Completed - verified March 2017

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