Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Catheter Ablation and Rate Control of Atrial Fibrillation in Patients With Heart Failure

Conditions:   Catheter Ablation;   Rate Control;   Heart Failure;   Atrial Fibrillation
Intervention:  
Sponsor:   Nanjing Medical University
Not yet recruiting - verified July 2016

Inflammatory Response as a Prognostic Factor of Recurrence of Atrial Fibrillation After Ablation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Medical University of Warsaw
Recruiting - verified July 2016

Factors Associated to the Instability of the INR (International Normalized Ratio ) in the Prevention of Thromboembolism AVK (Anti Vitamin K) in Atrial Fibrillation in the Elderly: Instead of Comorbidities

Condition:   Older Patient
Intervention:   Other: Charlson comorbidity index
Sponsor:   Nantes University Hospital
Completed - verified July 2016

Investigation of the Adagio PolarStar System in Patients With Paroxysmal Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Atrial Flutter
Intervention:   Device: PolarStar System
Sponsor:   Adagio Medical
Recruiting - verified July 2016

Sub-Clinical Atrial Fibrillation Biomarker Study

Condition:   Subclinical Atrial Fibrillation
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Population Health Research Institute;   Genome Canada
Not yet recruiting - verified July 2016

Ultrasound-guided Femoral Vein Accessibility, Safety and Time for Atrial Fibrillation Treatment

Conditions:   Atrial Fibrillation;   Peripheral Vascular Disease;   Vascular Access Complications
Interventions:   Device: Real-time ultrasound-guided puncture;   Other: Anatomical landmark guided puncture
Sponsor:   Kenichiro Yamagata
Recruiting - verified July 2016

Detection Rate of Atrial Fibrillation in Patients Implanted With ILRs

Condition:   Atrial Fibrillation
Intervention:   Other: No intervention
Sponsor:   Cambridge University Hospitals NHS Foundation Trust
Completed - verified July 2016

Review of the Safety and Effectiveness of the THERMOCOOL SMARTTOUCH® SF Catheter Evaluated for Treating Symptomatic PersistenT AF (PRECEPT)

Condition:   Atrial Fibrillation
Intervention:   Device: THERMOCOOL SMARTTOUCH® SF catheter
Sponsor:   Biosense Webster, Inc.
Recruiting - verified July 2016

TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis

Condition:   Aortic Valve Stenosis
Interventions:   Device: SAPIEN 3;   Procedure: SAVR
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2016

Age Related D-dimer Evaluation for the Exclusion of a Left Atrium Thrombus in Patients With Atrial Fibrillation (ADDIT-AF)

Condition:   Atrial Fibrillation
Intervention:   Procedure: Blood sampling
Sponsor:   Brugmann University Hospital
Not yet recruiting - verified July 2016

Treatment Convenience in Patients Treated With Dabigatran for Stroke Prophylaxis in Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension

Condition:   Hypertension Resistant to Conventional Therapy
Interventions:   Drug: Spironolactone;   Drug: Furosemide,;   Drug: Amiloride;   Drug: Ramipril;   Drug: Bisoprolol
Sponsor:   Sao Jose do Rio Preto University
Recruiting - verified July 2016

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsor:   Bayer
Recruiting - verified July 2016

Assessment of Reconstruction and Inverse Reconstruction in Right Atrium by Multimodal Echocardiographic Techniques

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: radiofrequency ablation (RFCA)
Sponsor:   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Recruiting - verified April 2016

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Conditions:   Mild Tricuspid Regurgitation;   Moderate Tricuspid Regurgitation;   Tricuspid Regurgitation
Interventions:   Procedure: TV Annuloplasty;   Procedure: MVS Alone
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   German Society for Thoracic and Cardiovascular Surgery
Recruiting - verified July 2016

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Patient Convenience Study

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified July 2016

Subtherapeutic INR Levels in Patients With AVK: Incidence, Associated Factors, Prognosis and Control Strategies

Condition:   Atrial Fibrillation
Intervention:   Drug: Vitamin K Antagonist
Sponsors:   Bayer;   Janssen Research & Development, LLC
Active, not recruiting - verified July 2016

AF Patient Preference Study

Condition:   Atrial Fibrillation
Interventions:   Drug: VKA: Warfarin (Waran);   Drug: NOAC: Rivaroxaban (Xarelto, BAY59-7939);   Drug: NOAC: Dabigatran etexilate;   Drug: NOAC: Apixaban;   Drug: NOAC: Edoxaban;   Drug: NOAC: Lixiana
Sponsor:   Bayer
Recruiting - verified July 2016

Influence of Sleep Apnea on Risk of Atrial Fibrillation

Conditions:   Sleep Apnea;   Atrial Fibrillation
Intervention:   Other: Continuous Positive Airway Pressure
Sponsors:   The Cleveland Clinic;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2016

Adherence to New Oral Anticoagulation Therapy in Turkey

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Cardiovascular Academy Society, Turkey
Completed - verified July 2016

Comparison Between Thoracoscopic Left Atrial Appendage Excision and Warfarin for the Secondary Prevention of Stroke in Patients With AF

Conditions:   Atrial Fibrillation;   Stroke;   Systemic Embolism
Interventions:   Procedure: Thoracoscopic Left Atrial Appendage Excision;   Drug: Warfarin
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified July 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified July 2016

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Active, not recruiting - verified July 2016

Amplatzer™Amulet™ Post-Market Study

Conditions:   Atrial Fibrillation;   Thromboembolism;   Stroke
Intervention:   Device: Subjects implanted with Amulet Device
Sponsor:   St. Jude Medical
Recruiting - verified July 2016

MediGuide Registry

Conditions:   Heart Failure;   Cardiac Arrhythmia
Interventions:   Procedure: CRT implantation;   Device: MediGuide;   Procedure: EP
Sponsor:   St. Jude Medical
Enrolling by invitation - verified July 2016

SMART-SF Radiofrequency Ablation Safety Study

Condition:   Atrial Fibrillation
Intervention:   Device: THERMOCOOL® SMARTTOUCH® (RF ablation treatment)
Sponsor:   Biosense Webster, Inc.
Active, not recruiting - verified July 2016

Validation of Ambulatory Sleep Test (WP200/U) Compared In-lab Sleep Testing in Cardiac Subjects

Condition:   Sleep Disorders
Intervention:  
Sponsor:   Itamar-Medical, Israel
Completed - verified April 2016

ABLATOR Ablation Observational Registry

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   St. Jude Medical
Active, not recruiting - verified July 2016

CCC Project - Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Beijing Institute of Heart, Lung and Blood Vessel Diseases;   American Heart Association;   Chinese Society of Cardiology
Recruiting - verified July 2016

Berlin Atrial Fibrillation Registry

Conditions:   Acute Ischemic Stroke;   Atrial Fibrillation
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Center for Stroke Research Berlin;   Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma
Recruiting - verified July 2016

REPRISE Next Generation Delivery System

Condition:   Aortic Stenosis
Intervention:   Device: Lotus Valve and LOTUS Edge Valve System
Sponsor:   Boston Scientific Corporation
Recruiting - verified July 2016

Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department

Condition:   Atrial Fibrillation
Interventions:   Drug: Pharmacological cardioversion - Flecainide;   Procedure: Electrical cardioversion;   Drug: Metoprolol;   Drug: Verapamil;   Drug: Digoxin;   Drug: Pharmacological cardioversion - Amiodarone
Sponsors:   Maastricht University Medical Center;   ZonMw: The Netherlands Organisation for Health Research and Development
Recruiting - verified July 2016

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Completed - verified June 2016

Effects of Marine n-3 Fatty Acids on Heart Rate Variability and Arrhythmias in Patients Receiving Chronic Dialysis

Conditions:   Kidney Failure Chronic;   Arrhythmias Cardiac
Interventions:   Dietary Supplement: dietary supplement: n-3 PUFA;   Dietary Supplement: olive oil
Sponsor:   Aalborg Universitetshospital
Completed - verified July 2016

Atrial Fibrillation, Cardiac Symptoms, and Anxiety

Conditions:   Atrial Fibrillation;   Anxiety
Intervention:   Behavioral: Mindfulness and Interoceptive Exposure
Sponsor:   Brigham and Women's Hospital
Suspended - verified July 2016

Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation

Condition:   Postoperative Atrial Fibrillation
Interventions:   Drug: Amiodarone;   Procedure: DC-cardioversion;   Drug: Rate Control
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   National Institute of Neurological Disorders and Stroke (NINDS);   Canadian Institutes of Health Research (CIHR)
Completed - verified July 2016

Swiss Atrial Fibrillation Cohort Study

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation;   Medical Image Analysis Center (MIAC) Basel;   Schiller AG Baar;   Clinical Trial Unit, University Hospital Basel, Switzerland;   Cardiovascular Research Institute (CRIB) Basel;   Cardiocentro Ticino
Recruiting - verified July 2016

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified July 2016

Rivaroxaban Versus Warfarin in Acute Ischemic Stroke With Atrial Fibrillation

Conditions:   Ischemic Stroke;   Transient Ischemic Attack
Interventions:   Drug: Rivaroxaban;   Drug: Warfarin
Sponsors:   Asan Medical Center;   Bayer
Completed - verified July 2016

Eliquis Safety Surveillance in Japanese Patients With NonValvular Atrial Fibrillation

Condition:   NonValvular Atrial Fibrillation
Intervention:   Drug: Eliquis
Sponsors:   Bristol-Myers Squibb;   Pfizer
Active, not recruiting - verified January 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified July 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified July 2016

A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurrence

Conditions:   Persistent Atrial Fibrillation;   Paroxysmal Atrial Fibrillation;   Hypertension;   Renal Denervation;   Cardiac Ablation
Interventions:   Device: Renal Artery Ablation Catheter;   Device: Cardiac Ablation
Sponsor:   St. Jude Medical
Recruiting - verified July 2016

Eliquis Regulatory Post Marketing Surveillance

Condition:   NonValvular Atrial Fibrillation
Intervention:   Drug: Apixaban
Sponsor:   Bristol-Myers Squibb
Recruiting - verified July 2016

Exploring the Efficacy of Once Daily Oral Rivaroxaban for Treatment of Thrombus in Left Atrial/Left Atrial Appendage in Subjects With Nonvalvular Atrial Fibrillation or Atrial Flutter

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Completed - verified December 2015

ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial

Condition:   End Stage Renal Failure on Dialysis
Interventions:   Drug: Spironolactone;   Drug: Placebo
Sponsors:   University Hospital, Brest;   Central Hospital, Nancy, France;   Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - verified July 2016

nMARQ™ Pulmonary Vein Isolation System for the Treatment of Paroxysmal Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Device: nMARQ Navigation Catheters;   Device: NaviStar ThermoCool Catheters
Sponsor:   Biosense Webster, Inc.
Active, not recruiting - verified July 2016

Canakinumab for the Prevention of Recurrences After Electrical Cardioversion: CONVERT-AF

Condition:   Atrial Fibrillation
Interventions:   Biological: Canakinumab;   Biological: Placebo
Sponsor:   University Hospital, Basel, Switzerland
Recruiting - verified July 2016

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Completed - verified July 2016

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa (Dabigatran etexilate mesilate)
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Continued Access to PREVAIL (CAP2)

Condition:   Atrial Fibrillation
Intervention:   Device: WATCHMAN LAA Closure Technology
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified July 2016

ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal AF

Conditions:   Persistent Atrial Fibrillation;   Longstanding Persistent Atrial Fibrillation
Intervention:   Device: Synergy Ablation System
Sponsor:   AtriCure, Inc.
Active, not recruiting - verified July 2016

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Completed - verified May 2016

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Early Percutaneous Mitral Intervention in Asymptomatic Moderate Mitral Stenosis

Condition:   Moderate Mitral Stenosis
Intervention:   Procedure: Percutaneous Mitral Commissurotomy
Sponsor:   Asan Medical Center
Active, not recruiting - verified July 2016

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Conditions:   Heart; Dysfunction Postoperative, Cardiac Surgery;   Genetic Predisposition to Disease;   Atrial Fibrillation;   Myocardial Infarction;   Heart Failure
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   Texas Heart Institute;   University of Texas Southwestern Medical Center
Recruiting - verified July 2016

Use of the Hansen Medical System in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: Ablation
Sponsor:   Hansen Medical
Active, not recruiting - verified July 2016

Intravenous Lidocaine and Postoperative Outcomes After Cardiac Surgery

Condition:   Atrial Fibrillation
Interventions:   Drug: Lidocaine;   Other: Placebo
Sponsor:   The Cleveland Clinic
Recruiting - verified July 2016

Gene Expression Profiling in Subjects With Postoperative Atrial Fibrillation After Cardiac Surgery

Condition:   Atrial Fibrillation
Intervention:   Other: Atrial biopsy
Sponsor:   Brigham and Women's Hospital
Recruiting - verified July 2016

Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery

Condition:   Cardiac Surgery
Interventions:   Other: Hyperinsulinemic-normoglycemic clamp;   Other: insulin at the standard of care levels
Sponsor:   The Cleveland Clinic
Recruiting - verified July 2016

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