Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Adherence to New Oral Anticoagulation Therapy in Turkey

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Cardiovascular Academy Society, Turkey
Not yet recruiting - verified June 2015

Comparison Between Thoracoscopic Left Atrial Appendage Excision and Warfarin for the Secondary Prevention of Stroke in Patients With AF

Conditions:   Atrial Fibrillation;   Stroke;   Systemic Embolism
Interventions:   Procedure: Thoracoscopic Left Atrial Appendage Excision;   Drug: Warfarin
Sponsor:   The First Hospital of Nanjing Medical University
Active, not recruiting - verified June 2015

a Novel Individualized Substrate Modification Approach for the Treatment of Long-standing Persistent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: individualized substrate modification;   Procedure: stepwise ablation
Sponsors:   RenJi Hospital;   Biosense Webster, Inc.
Recruiting - verified January 2015

Comparison of Operator-guided and Automatic Algorithm-guided Atrial Fibrillation Ablation

Condition:   Atrial Fibrillation
Intervention:   Procedure: Ablation using CARTO system
Sponsors:   Military Institute of Medicine, Poland;   Medical University of Warsaw;   Institute of Cardiology, Warsaw, Poland
Recruiting - verified June 2015

Study of ACP-196 Versus Ibrutinib in Previously Treated Subjects With High Risk Chronic Lymphocytic Leukemia

Condition:   Chronic Lymphocytic Leukemia
Interventions:   Drug: ACP-196;   Drug: ibrutinib
Sponsor:   Acerta Pharma BV
Not yet recruiting - verified June 2015

WATCHMAN Implantation During Hybrid Ablation

Conditions:   Atrial Fibrillation;   Stroke
Intervention:   Device: WATCHMAN Device implantation
Sponsors:   Maastricht University Medical Center;   Boston Scientific Corporation
Not yet recruiting - verified June 2015

Amplatzer™Amulet™ Post-Market Study

Conditions:   Atrial Fibrillation;   Thromboembolism;   Stroke
Intervention:   Device: Subjects implanted with Amulet Device
Sponsor:   St. Jude Medical
Recruiting - verified June 2015

Surgical Prevention of Atrial Fibrillation in Patients With Rheumatic Mitral Valve Lesion and Left Atrium Enlargement

Conditions:   Atrial Fibrillation;   Rheumatic Heart Disease
Interventions:   Procedure: surgical prevention of atrial fibrillation;   Device: cardiomonitor
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified June 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Not yet recruiting - verified May 2015

Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach

Conditions:   Atrial Fibrillation;   Persistent or Longstanding Persistent Atrial Fibrillation
Intervention:   Device: AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation
Sponsor:   AtriCure, Inc.
Recruiting - verified June 2015

Validation of Ambulatory Sleep Test (WP200/U) Compared In-lab Sleep Testing in Cardiac Subjects

Condition:   Sleep Disorders
Intervention:  
Sponsor:   Itamar-Medical, Israel
Recruiting - verified June 2015

Weaning of Norepinephrine Guided by the Dynamic Arterial Compliance in Cardiac Surgery Post Operative.

Condition:   Vasoplegic Syndrome
Interventions:   Drug: Norepinephrine;   Drug: Norepinephrine
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified June 2015

Uninterrupted Dabigatran Etexilate in Comparison to Uninterrupted Warfarin in Pulmonary Vein Ablation (RE-CIRCUIT)

Condition:   Atrial Fibrillation
Interventions:   Drug: Warfarin;   Drug: Dabigatran Etexilate 150mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2015

Prospective, Randomized Comparison of Hybrid Ablation vs. Catheter Ablation (PRHACA)

Condition:   Persistent Atrial Fibrillation
Interventions:   Device: endocardial ablation (Medtronic);   Device: hybrid surgical ablation (nContact)
Sponsor:   Jasbir Sra
Recruiting - verified June 2015

Canadian Community Utilization of Stroke Prevention Study - Emergency Department

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Other: Retrospective review of OAC prescription;   Other: Prescription of OAC in ED;   Other: Community AF clinic
Sponsor:   Population Health Research Institute
Recruiting - verified June 2015

Evaluation of 5 Days Holter and 30 Days Thumb-ECG for Detection of Atrial Fibrillation in Stroke Patients

Conditions:   Atrial Fibrillation;   Stroke
Intervention:   Device: Holter monitoring and Thumb ECG
Sponsor:   Herlev Hospital
Completed - verified June 2015

Right Ventricle (RV) Markers of Future Pacing Induced Ventricular Dysfunction - Pilot

Condition:   Sick Sinus Syndrome
Intervention:  
Sponsors:   Basildon and Thurrock University Hospitals NHS Foundation Trust;   Anglia Ruskin University
Recruiting - verified June 2015

Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers

Condition:   Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Sotalol;   Drug: Placebo for BMS-919373
Sponsor:   Bristol-Myers Squibb
Recruiting - verified January 2015

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Recruiting - verified April 2015

Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation

Condition:   Postoperative Atrial Fibrillation
Interventions:   Drug: Amiodarone;   Procedure: DC-cardioversion;   Drug: Rate Control
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   National Institute of Neurological Disorders and Stroke (NINDS);   Canadian Institutes of Health Research  (CIHR)
Active, not recruiting - verified June 2015

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified June 2015

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation

Conditions:   Heart Disease;   Congestive Heart Failure;   Atrial Fibrillation
Interventions:   Device: Optimal Medical therapy plus ICD;   Device: Optimal Medical therapy plus CRT/ICD
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified June 2015

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Other: None - this is an observational study
Sponsors:   University of Virginia;   National Heart, Lung, and Blood Institute (NHLBI);   Oxford University Hospitals NHS Trust
Recruiting - verified June 2015

A Study of the Safety and Efficacy of the VytronUS Low-Intensity Collimated Ultrasound Ablation System

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: VytronUS Ablation System
Sponsor:   VytronUS, Inc.
Completed - verified June 2015

Eliquis Regulatory Post Marketing Surveillance

Condition:   NonValvular Atrial Fibrillation
Intervention:   Drug: Apixaban
Sponsor:   Bristol-Myers Squibb
Recruiting - verified June 2015

Assessment of an Education and Guidance Programme for Eliquis Adherence in Non-Valvular Atrial Fibrillation (AEGEAN)

Condition:   Non-valvular Atrial Fibrillation
Intervention:   Drug: Apixaban
Sponsor:   Bristol-Myers Squibb
Recruiting - verified December 2014

A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: rivaroxaban 2.5 mg;   Drug: rivaroxaban 15 mg;   Drug: rivaroxaban 10 mg;   Drug: aspirin (ASA);   Drug: vitamin K antagonist (VKA);   Drug: clopidogrel;   Drug: prasugrel;   Drug: ticagrelor
Sponsors:   Janssen Scientific Affairs, LLC;   Bayer
Recruiting - verified June 2015

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified June 2015

Management and Detection of Atrial Tachyarrhythmias in Patients Implanted With BIOTRONIK DX Systems

Conditions:   Atrial Fibrillation;   Tachycardia;   ICD Therapy;   Thromboembolic Events;   Heart Failure
Intervention:  
Sponsor:   Biotronik SE & Co. KG
Recruiting - verified June 2015

DF4 Master Study (Safety and Efficacy Study)

Conditions:   Ventricular Tachycardia;   Ventricular Fibrillation;   Sudden Cardiac Death;   Heart Failure
Intervention:   Device: Iforia/Ilesto ICD/CRT-D, Linox smart DF4 lead/ Protego
Sponsor:   Biotronik SE & Co. KG
Active, not recruiting - verified June 2015

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II)

Condition:   Atrial Fibrillation
Intervention:   Other: Patients with Atrial Fibrillation
Sponsors:   Janssen Scientific Affairs, LLC;   Duke Clinical Research Institute
Recruiting - verified June 2015

Ventricular Pace Suppression Versus Intrinsic Rhythm Support Study

Condition:   Sick Sinus Syndrome
Interventions:   Other: Ventricular Pace Suppression (Vps);   Other: Intrinsic rhythm support (IRSplus)
Sponsor:   Biotronik SE & Co. KG
Active, not recruiting - verified June 2015

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2015

Early Percutaneous Mitral Intervention in Asymptomatic Moderate Mitral Stenosis

Condition:   Moderate Mitral Stenosis
Intervention:   Procedure: Percutaneous Mitral Commissurotomy
Sponsor:   Asan Medical Center
Recruiting - verified June 2015

Recurrence of Arrhythmias After Pulmonary Veins Isolation Detected by ICM

Condition:   Atrial Fibrillation
Intervention:   Device: ICM Implantation
Sponsor:   Dr Ange FERRACCI
Completed - verified June 2015

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