Atrial Fibrillation Also called: AF, AFib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Noninvasive 3D Mapping in Persistent Atrial Fibrillation, to Describe Modifications of the Arrhythmogenic Substrate After Pulmonary Vein Isolation and Identify Potential Predicting Factors of Ablation Success

Condition:   Atrial Fibrillation, Persistent
Interventions:   Device: Noninvasive mapping (Cardioinsight® system);   Device: long-term cardiac monitoring (LINQ system);   Procedure: Atrial Fibrillation ablation procedure
Sponsor:   University Hospital, Rouen
Not yet recruiting

Biatrial Global High-density Electroanatomical Mapping of Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Procedure: Simultaneous bi-atrial electroanatomic mapping and ablation
Sponsor:   Oxford University Hospitals NHS Trust
Recruiting

Comparison of Two Strategies for the Management of Atrial Fibrillation After Cardiac Surgery

Conditions:   Atrial Fibrillation;   Cardiac Surgery
Interventions:   Drug: Landiolol;   Drug: Amiodarone
Sponsor:   University Hospital, Caen
Recruiting

Role of Exosomes Derived From Epicardial Fat in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Procedure: Epicardial fat biopsy
Sponsor:   Sheba Medical Center
Recruiting

Validation of Software for Assessment of Atrial Fibrillation From Data Acquired by a Wearable Smartwatch

Condition:   Atrial Fibrillation
Intervention:   Diagnostic Test: Electrocardiogram
Sponsor:   Fitbit Inc
Active, not recruiting

aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Device: LARIAT + PVI;   Device: Pulmonary Vein Isolation
Sponsor:   AtriCure, Inc.
Recruiting

Use of Oral Anticoagulants and Symptoms in Patients With Atrial Fibrillation in Örebro County

Conditions:   Atrial Fibrillation;   Stroke, Ischemic
Intervention:   Drug: Oral anticoagulant
Sponsor:   Region Örebro County
Recruiting

A Fib Clinic of the Future Using KardiaPro Platform for Chronic Care of Patients With AF After Ablation Procedure

Condition:   Atrial Fibrillation
Intervention:   Device: Kardia Monitoring
Sponsors:   The Cleveland Clinic;   AliveCor
Active, not recruiting

DiamondTemp™ Ablation System for the Treatment of Paroxysmal Atrial Fibrillation

Conditions:   Paroxysmal Atrial Fibrillation;   Atrial Fibrillation
Interventions:   Device: DiamondTemp Ablation catheter;   Device: TactiCath Quartz Ablation catheter
Sponsor:   EPIX Therapeutics
Completed

CardioFocus vs. Contact Force Guided Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: Ablation catheter
Sponsor:   I-Med-Pro GmbH
Recruiting

Characterising the Stable and Dynamic Left Atrial Substrate in Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Diagnostic Test: High density electrophysiological mapping;   Diagnostic Test: Cardiac Magnetic Resonance Imaging
Sponsor:   Oxford University Hospitals NHS Trust
Not yet recruiting

The 'Ablate By-LAW' Study

Condition:   Atrial Fibrillation
Intervention:   Procedure: Personalized atrial fibrillation ablation
Sponsors:   Centro Medico Teknon;   Heart and Diabetes Center North Rhine-Westphalia;   Azienda Ospedaliero, Universitaria Pisana;   Heart Center Leipzig - University Hospital;   Hospital Universitario Puerta del Mar;   Beth Israel Deaconess Medical Center;   University of Pennsylvania
Not yet recruiting

IDE Trial for Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: POLARx™ Cardiac Cryoablation System
Sponsor:   Boston Scientific Corporation
Not yet recruiting

Safety and Effectiveness Evaluation of the Multi-Electrode Radiofrequency Balloon Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Device: Radiofrequency Ablation
Sponsor:   Biosense Webster, Inc.
Recruiting

A Trial of High Power-Short Duration Versus Standard Power-Long Duration Radiofrequency Ablation for Treatment of Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Atrial Fibrillation Paroxysmal;   Atrial Fibrillation, Persistent
Interventions:   Procedure: Catheter ablation with Standard RF ablation settings;   Procedure: Catheter ablation with High Power Short Duration RF ablation settings
Sponsor:   University of California, San Francisco
Recruiting

Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: Boston Scientific Open Irrigated Ablation Catheters
Sponsor:   Boston Scientific Corporation
Recruiting

Pulsewatch: Smartwatch Monitoring for Atrial Fibrillation After Stroke

Conditions:   Stroke;   Atrial Fibrillation
Interventions:   Device: Testing Devices;   Device: Cardea Solo by Cardiac Insight;   Device: Kardia Mobile by AliveCor
Sponsors:   University of Massachusetts, Worcester;   University of Connecticut;   Northeastern University;   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Study to Learn More About the Benefits and Side-effects of Drugs Rivaroxaban and Apixaban Compared to the Drug Warfarin for Stroke Prevention in Patients With Rapid and Irregular Heartbeat Which is Not Due to a Heart-valve Fault (Non-valvular Atrial Fibrillation) in the UK Routine Clinical Practice

Condition:   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Apixaban (Eliquis);   Drug: Warfarin
Sponsors:   Bayer;   Janssen, LP
Active, not recruiting

Tragus Stimulation to Prevent Atrial Fibrillation After Cardiac Surgery

Condition:   Atrial Fibrillation
Intervention:   Device: Parasym
Sponsors:   University of Chicago;   Parasym Ltd.
Recruiting

Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy

Condition:   Atrial Fibrillation
Interventions:   Device: CE-mark approved LAA closure devices;   Drug: Acetylsalicylic acid;   Drug: Clopidogrel;   Drug: Dabigatran;   Drug: Rivaroxaban;   Drug: Apixaban;   Drug: Edoxaban;   Drug: Phenprocoumon;   Drug: Warfarin
Sponsors:   Charite University, Berlin, Germany;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK);   Atrial Fibrillation Network;   Stiftung Institut fuer Herzinfarktforschung
Recruiting

Finding Atrial Fibrillation in Stroke - Evaluation of Enhanced and Prolonged Holter Monitoring

Condition:   Stroke
Interventions:   Other: prolonged ECG monitoring;   Other: standard care
Sponsor:   Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Completed

AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment

Conditions:   Atrial Fibrillation;   Persistent Atrial Fibrillation;   Longstanding Persistent Atrial Fibrillation
Intervention:   Device: AtriCure CryoICE & AtriClip LAA Exclusion
Sponsor:   AtriCure, Inc.
Recruiting

Study Aims to Collect Information in Routine Clinical Practice in Italy About the Number of Patients Suffering From Irregularly Heart Beats Which Are Not Caused by a Heart Valve Problem (Non-valvular Atrial Fibrillation, NVAF) Who Stopped or Changed Rivaroxaban Treatment

Condition:   Non-valvular Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting

iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology

Conditions:   Atrial Fibrillation;   Atrial Flutter
Interventions:   Device: AliveCor;   Behavioral: Behavioral Altering Messaging
Sponsor:   Columbia University
Active, not recruiting

Burden of Ischemic Stroke and Intake of Oral Anticoagulants in Patients With Atrial Fibrillation in the UK Primary Care

Condition:   Atrial Fibrillation
Intervention:   Drug: Oral anticoagulant
Sponsor:   Bayer
Not yet recruiting

Gene Expression Profiling in Subjects With Postoperative Atrial Fibrillation After Cardiac Surgery

Condition:   Atrial Fibrillation
Intervention:   Other: Atrial biopsy
Sponsor:   Brigham and Women's Hospital
Recruiting

Indonesian Registry on Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Indonesian Heart Rhythm Society
Recruiting

IvaBRAdine blocK of Funny Current for Heart Rate Control in permanEnt Atrial Fibrillation. (BRAKE-AF Study).

Conditions:   Atrial Fibrillation;   Heart Diseases
Interventions:   Drug: Ivabradine;   Drug: Digoxin
Sponsors:   Adolfo Fontenla;   Spanish Clinical Research Networt (SCReN);   Carlos III Health Institute
Recruiting

CCC Project - Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Beijing Institute of Heart, Lung and Blood Vessel Diseases;   American Heart Association;   Chinese Society of Cardiology
Recruiting

Evaluation of Vein of Marshall Ethanol Infusion During Left Atrial Linear Ablation in Patients With Persistent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: ALINE + VoM infusion;   Procedure: ALINE only
Sponsor:   AZ Sint-Jan AV
Recruiting

Systematic Evaluation of Ablation Techniques for Non-Paroxysmal Atrial Fibrillation.

Condition:   Atrial Fibrillation
Intervention:   Procedure: Catheter ablation
Sponsors:   Montefiore Medical Center;   Biosense Webster, Inc.
Not yet recruiting

Non-Interventional Study on Effectiveness of Elxaban Tab. in Patients With Non-valvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Yonsei University
Recruiting

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Conditions:   Atrial Fibrillation;   Stroke;   Bleeding
Interventions:   Drug: Antiplatelet-only strategy;   Drug: Oral Anticoagulant plus background antiplatelet therapy
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Vanderbilt University Medical Center
Recruiting

Study to Gather Information About the Proper Dosing of the Oral FXIa Inhibitor BAY 2433334 and to Compare the Safety of the Study Drug to Apixaban, a Non-vitamin K Oral Anticoagulant (NOAC) in Patients With Irregular Heartbeat (Atrial Fibrillation) That Can Lead to Heart-related Complications.

Condition:   Atrial Fibrillation (AF)
Interventions:   Drug: BAY2433334;   Drug: Apixaban;   Other: BAY2433334 matching placebo;   Other: Apixaban matching placebo
Sponsor:   Bayer
Not yet recruiting

Reducing Atrial Pacing Rate to Reduce Atrial Fibrillation in Patients With Sick Sinus Syndrome.

Conditions:   Sinus Node Disease;   Atrial Fibrillation
Interventions:   Device: DDDR-60;   Device: DDD-40
Sponsors:   Aarhus University Hospital;   Aalborg University Hospital;   Herning Hospital;   Regionshospitalet Viborg, Skive;   Aabenraa Hospital;   Sydvestjysk Hospital;   Vejle Hospital;   Odense University Hospital;   Zealand University Hospital;   Rigshospitalet, Denmark;   Bispebjerg Hospital;   University Hospital, Gentofte, Copenhagen;   Hillerod Hospital, Denmark
Recruiting

Investigation of Substrates Associated With the Recurrence of Atrial Fibrillation After PV Cryoablation

Condition:   Atrial Fibrillation
Intervention:   Procedure: Cryoablation of the pulmonary veins and myocardial biopsy
Sponsors:   National Research Center for Preventive Medicine;   I.M. Sechenov First Moscow State Medical University
Completed

Xarelto on Prevention of Stroke and Non-Central Nervous Systemic Embolism in Renally Impaired Korean Patients With Non-valvular Atrial Fibrillation

Condition:   Non-valvular Atrial Fibrillation (NVAF)
Intervention:   Drug: Rivaroxaban(Xarelto,BAY 59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting

Strategies for the Management of Atrial Fibrillation in patiEnts Receiving HemoDialysis

Conditions:   Atrial Fibrillation;   End Stage Renal Failure on Dialysis
Interventions:   Drug: Warfarin;   Drug: Apixaban;   Other: No oral anticoagulation
Sponsors:   St. Michael's Hospital, Toronto;   Canadian Institutes of Health Research (CIHR)
Recruiting

Atrial Fibrillation Health Literacy and Information Technology Trial in Rural PA Counties

Conditions:   Atrial Fibrillation;   Familial Atrial Fibrillation;   Arrhythmia, Cardiac;   Heart Diseases;   Pathologic Processes
Interventions:   Behavioral: Relational agent/AliveCor Kardia - Intervention Group;   Behavioral: Usual Care
Sponsors:   University of Pittsburgh;   National Heart, Lung, and Blood Institute (NHLBI);   Northeastern University;   Boston University
Recruiting

Atrial Fibrillation Health Literacy and Information Technology Trial in Pittsburgh, PA

Conditions:   Atrial Fibrillation;   Familial Atrial Fibrillation;   Arrythmia, Cardiac;   Heart Diseases;   Pathologic Processes
Interventions:   Behavioral: Relational Agent and heart rate and rhythm monitor;   Behavioral: Usual Care
Sponsors:   University of Pittsburgh;   National Heart, Lung, and Blood Institute (NHLBI);   Northeastern University;   Boston University
Recruiting

A Study to Determine if Identification of Undiagnosed Atrial Fibrillation in People at Least 70 Years of Age Reduces the Risk of Stroke

Conditions:   Atrial Fibrillation;   Atrial Flutter
Intervention:   Other: AF Detection Intervention
Sponsors:   Bristol-Myers Squibb;   Pfizer
Recruiting

COlchicine in Cardiac Surgery

Conditions:   Colchicine Adverse Reaction;   Atrial Fibrillation New Onset
Interventions:   Drug: Colchicine;   Drug: Placebo
Sponsor:   Bakulev Scientific Center of Cardiovascular Surgery
Recruiting

Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Hypertension
Interventions:   Device: Renal nerve denervation;   Device: Cryoablation
Sponsor:   Medtronic Cardiac Rhythm and Heart Failure
Recruiting

Atrial Fibrillation Detected by Continuous ECG Monitoring

Conditions:   Atrial Fibrillation;   Stroke;   Hypertension;   Diabetes
Intervention:   Device: Implantable loop recorder (Medtronic Reveal LINQ(TM))
Sponsors:   Rigshospitalet, Denmark;   Bispebjerg Hospital;   Zealand University Hospital;   Odense University Hospital;   University of Southern Denmark;   Aalborg University
Active, not recruiting

INhalation of Flecainide to Convert Recent Onset SympTomatic Atrial Fibrillation to siNus rhyThm (INSTANT)

Condition:   Paroxysmal Atrial Fibrillation (PAF)
Intervention:   Drug: Flecainide Acetate
Sponsor:   InCarda Therapeutics Australia Pty Ltd.
Recruiting

Non-interventional Study on Patients With Atrial Fibrillation and Cancer

Conditions:   Atrial Fibrillation;   Cancer
Intervention:  
Sponsor:   Heart Care Foundation
Recruiting

Esophageal Cooling for AF Ablation

Condition:   Atrial Fibrillation
Interventions:   Device: Esophageal Cooling;   Device: Control
Sponsors:   University of Pennsylvania;   Attune Medical
Recruiting

Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation

Condition:   Stroke
Intervention:   Other: Time-To-Treatment Randomization
Sponsors:   University of Texas at Austin;   Lone Star Stroke Research Consortium;   Texas Department of State Health Services
Recruiting

Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass

Conditions:   Coronary Artery Disease;   Stroke;   Atrial Fibrillation
Intervention:   Procedure: Left Atrial Appendage Resection and Marshall Ligament Amputation
Sponsor:   China National Center for Cardiovascular Diseases
Not yet recruiting

Assessment of Quitting Versus Using Aspirin Therapy In Patients Treated With Oral Anticoagulation for Atrial Fibrillation With Stabilized Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Drug: OAC + Aspirin 100mg od;   Drug: OAC + placebo of Aspirin 100mg od
Sponsors:   University Hospital, Brest;   Bayer
Not yet recruiting

Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach

Conditions:   Atrial Fibrillation;   Persistent or Longstanding Persistent Atrial Fibrillation
Intervention:   Device: AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation
Sponsor:   AtriCure, Inc.
Recruiting

Rivaroxaban Utilization for Treatment and Prevention of Thromboembolism in Cancer Patients: Experience at a Comprehensive Cancer Center

Conditions:   Cancer;   Deep-vein Thrombosis of the Lower and Upper Extremities;   Pulmonary Embolism;   Non-valvular Atrial Fibrillation
Intervention:   Other: Retrospective Chart Review
Sponsors:   M.D. Anderson Cancer Center;   Janssen Scientific Affairs, LLC
Active, not recruiting

Early Rivaroxaban for Acute Ischemic Stroke or TIA Patients With Atrial Fibrillation

Conditions:   Cerebral Infarction;   TIA
Intervention:   Drug: Rivaroxaban
Sponsor:   General Hospital of Shenyang Military Region
Recruiting

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

Condition:   Persistent Atrial Fibrillation
Interventions:   Device: Convergent Procedure EPi-Sense-AF Guided Coagulation System;   Device: Endocardial Catheter Ablation
Sponsor:   AtriCure, Inc.
Active, not recruiting

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting

Clinical Usefulness of Virtual Antiarrhythmic Drug Test in Patients With Recurred AF After Catheter Ablation(CUVIA-AF3)

Condition:   Atrial Fibrillation
Interventions:   Drug: Virtual AAD TEST group;   Drug: Empirical AAD group
Sponsor:   Yonsei University
Not yet recruiting

Topera E-FIRM Registry

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Abbott Medical Devices;   I-Med-Pro GmbH
Completed

Risk Factors of Outcomes Associated With Disease Progression in Patients With Atrial Fibrillation and Heart Failure (HF) Who Are Receiving a Direct Oral Anticoagulant (Rivaroxaban)

Condition:   Heart Failure
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Active, not recruiting

Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus

Condition:   Atrial Fibrillation
Interventions:   Diagnostic Test: Contrast enhanced ECG-gated cardiac CT (CCT);   Diagnostic Test: Transesophageal Echocardiography (TEE)
Sponsor:   Ottawa Heart Institute Research Corporation
Not yet recruiting

Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF

Condition:   Atrial Fibrillation
Intervention:   Device: Medtronic Pulsed Field Ablation (PFA) System
Sponsor:   Medtronic Cardiac Rhythm and Heart Failure
Recruiting

Evaluating Active Esophageal Cooling During Cardiac Ablation Procedures

Condition:   Atrial Fibrillation
Intervention:   Device: esophageal cooling device (Attune Medical, Chicago, IL)
Sponsors:   Advanced Cooling Therapy, LLC;   University of Iowa
Recruiting

Amplatzer Amulet LAAO vs. NOAC

Conditions:   Atrial Fibrillation;   Stroke;   Bleeding
Interventions:   Device: Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder);   Drug: Non-Vitamin K Oral Antagonists
Sponsor:   Abbott Medical Devices
Not yet recruiting

Evaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU)

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: Catheter ablation with EPU
Sponsor:   Biosense Webster, Inc.
Recruiting

FIRE AND ICE II Trial Pilot

Conditions:   Persistent Atrial Fibrillation;   Atrial Arrhythmia
Interventions:   Device: Cryoballoon (Arctic Front Advance Cryoballoon);   Device: Radiofrequency Catheter (ThermoCool Smarttouch)
Sponsors:   Medtronic Cardiac Rhythm and Heart Failure;   genae associates (CRO), Antwerp, Belgium;   King's College London;   Deutsches Herzzentrum Muenchen
Recruiting

Study of DU-176b Aged 80 Years or Older

Condition:   Atrial Fibrillation
Interventions:   Drug: Du-176b;   Drug: placebo
Sponsor:   Daiichi Sankyo Co., Ltd.
Active, not recruiting

CLOSE-guided Pulmonary Vein Isolation Using High Power and Stable RF Applications

Condition:   Atrial Fibrillation
Interventions:   Procedure: High power CLOSE-guided PVI ablation;   Procedure: Standard CLOSE-guided PVI ablation
Sponsor:   AZ Sint-Jan AV
Recruiting

This Study Looks at the Effects of Idarucizumab in Patients Who Take Dabigatran and Need Emergency Surgery or Are Bleeding

Condition:   Atrial Fibrillation
Intervention:   Drug: Idarucizumab
Sponsor:   Boehringer Ingelheim
Recruiting

Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion

Conditions:   Atrial Fibrillation;   Atrial Flutter
Interventions:   Drug: Propofol;   Drug: Methohexital
Sponsor:   Wake Forest University Health Sciences
Not yet recruiting

Introductory Clinical Trial for Measuring Patients Before, During, and After an Electrophysiology (EP) Procedure With a Novel, Body-Worn Sensor

Conditions:   Atrial Fibrillation;   Ventricular Tachycardia
Intervention:   Diagnostic Test: CoVa 2 Sensor
Sponsor:   NYU Langone Health
Recruiting

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Research & Development, LLC
Completed

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Completed

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Conditions:   Acute Coronary Syndrome;   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Active, not recruiting

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Conditions:   Heart; Dysfunction Postoperative, Cardiac Surgery;   Genetic Predisposition to Disease;   Atrial Fibrillation;   Myocardial Infarction;   Heart Failure
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   Texas Heart Institute;   University of Texas Southwestern Medical Center
Recruiting

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin;   Drug: Antiplatelet drugs
Sponsors:   Bayer;   Janssen Research & Development, LLC
Completed

Early Percutaneous Mitral Intervention in Asymptomatic Moderate Mitral Stenosis

Condition:   Moderate Mitral Stenosis
Intervention:   Procedure: Percutaneous Mitral Commissurotomy
Sponsor:   Asan Medical Center
Active, not recruiting

A Randomized Clinical Trial of Resuming Direct Oral Anticoagulant Therapy Following Major Hemorrhage

Conditions:   Hemorrhage;   Intracranial Hemorrhages;   CVA; Hemorrhagic;   Bleeding
Intervention:   Drug: Anticoagulants
Sponsor:   University of Texas at Austin
Not yet recruiting

Development of a Multivariable Prognostic PREdiction Model for 1-year Risk of FALLing in Community-dwelling Older Adults in a Non-clinical Setting

Conditions:   Accidental Fall;   Fall
Intervention:  
Sponsor:   Aalborg University Hospital
Active, not recruiting

Bifocal Right Ventricular PAcing in Right Bundle Branch blocK and Heart Failure With Reduced Ejection Fraction. The Study Tests the Superiority of Right Ventricular Bifocal Stimulation Over VVI Implantable Defibrillator in Right Bundle Branch Block and Heart Failure.

Conditions:   Right Bundle-Branch Block;   Heart Failure With Reduced Ejection Fraction;   Bifocal Stimulation
Intervention:   Device: Compare VVi mode versus DDD bifocal stimulation through crossover randomization
Sponsor:   Azienda Ospedaliero Universitaria Maggiore della Carita
Recruiting

Cardiovascular Events in Chronic Obstructive Pulmonary Disease Patients Initiating Olodaterol or Other Long-acting beta2 Agonists

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting

Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes

Condition:   Transcatheter Aortic Valve Replacement
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Acetylsalicylic Acid (ASA);   Drug: Clopidogrel;   Drug: Vitamin K antagonist (VKA)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Terminated

Prolonged Continuous ECG Monitoring Prior to Transcatheter Aortic Valve Implantation

Conditions:   Aortic Valve Stenosis;   Arrythmia
Intervention:   Device: ECG monitoring
Sponsor:   Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Recruiting

Anesthetic Techniques in EP Patients

Condition:   Cardiac Disease
Interventions:   Drug: Propofol;   Drug: Ketamine;   Drug: Remifentanil;   Drug: Sevoflurane
Sponsor:   University of California, Los Angeles
Terminated

Myocardial Infarction With Non-Obstructive Coronary Arteries in the Greek Population

Conditions:   Acute Myocardial Infarction;   Non-Obstructive Coronary Atherosclerosis;   Ischemic Heart Disease;   Angina Pectoris;   Coronary Microvascular Disease
Interventions:   Other: MINOCA registry;   Diagnostic Test: CCTA Phenotypes
Sponsor:   AHEPA University Hospital
Not yet recruiting

Transcatheter Aortic Valve Replacement Versu Surgical Aortix Valve Replacement for Treating Elderly Patients With Severe Aortic Stenosis and Small Aortic Annuli: A Prospective Randomized Study The VIVA Trial

Conditions:   Degenerative Aortic Valve Disease;   Aortic Stenosis;   Aortic Regurgitation
Interventions:   Procedure: Edwards;   Procedure: CoreValve;   Procedure: Standard
Sponsor:   Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Recruiting

Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy

Conditions:   Postpartum Hemorrhage;   Twin
Intervention:   Drug: Oxytocin
Sponsor:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting

Carbetocin vs. Oxytocin at Elective Cesarean Section

Condition:   Postpartum Hemorrhage
Interventions:   Drug: Carbetocin;   Drug: Oxytocin
Sponsor:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting

Clinical Benefits of the Closed Loop Stimulation in Sinus Node Disease

Condition:   Sinus Node Disease
Interventions:   Device: DDD+CLS;   Device: DDD(R)
Sponsor:   Biotronik SE & Co. KG
Active, not recruiting

DANISH-CRT - Does Electric Targeted LV Lead Positioning Improve Outcome in Patients With Heart Failure and Prolonged QRS

Conditions:   Heart Failure;   Branch Block, Bundle
Intervention:   Device: Implantation of a Cardiac Resynchronisation Therapy (CRT) pacing device with or without Implanted Cardioverter Defibrillator
Sponsors:   Aarhus University Hospital;   Aalborg University Hospital;   Odense University Hospital;   Rigshospitalet, Denmark;   Gentofte University Hospital
Recruiting

Trends in the Epidemiology and Treatment of Atopic Dermatitis in the United Kingdom (UK)

Conditions:   Atopic Dermatitis Eczema;   Atopic Dermatitis;   Eczema
Intervention:   Other: No intervention
Sponsors:   Momentum Data;   Pfizer;   Royal College of General Practitioners Research and Surveillance Centre
Active, not recruiting

Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass

Conditions:   Cardiac Disease;   Bleeding Postoperative
Interventions:   Other: Fresh Autologous whole Blood;   Other: Standard of Care Expectant management of bleeding
Sponsor:   University of Colorado, Denver
Not yet recruiting

Ambulatory Electrocardiographic Monitoring for the Detection of High-Degree Atrio-Ventricular Block in Patients With New-onset PeRsistent LEft Bundle Branch Block After Transcatheter Aortic Valve Implantation. The "MARE" Study

Conditions:   Aortic Valve Disease;   Conduction Disturbances
Intervention:   Device: Implantable loop recorders system Reveal ICM LINQ®,
Sponsor:   Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Recruiting

Bariatric Surgery for the Reduction of cArdioVascular Events Feasibility Trial

Conditions:   Obesity, Morbid;   Cardiovascular Diseases
Intervention:   Procedure: Bariatric surgery
Sponsors:   Hamilton Health Sciences Corporation;   Population Health Research Institute;   St. Joseph's Healthcare Hamilton
Not yet recruiting

REVERSE-AKI Randomized Controlled Pilot Trial

Conditions:   Acute Kidney Injury;   Critical Illness
Intervention:   Other: Restrictive fluid management
Sponsors:   Helsinki University Central Hospital;   Austin Hospital, Melbourne Australia;   Guy's and St Thomas' NHS Foundation Trust;   University Hospital, Ghent;   Medical University Innsbruck;   Lausanne University Hospital
Recruiting

Identification of Prognostic Parameters in Patients With " Senile " Amyloid Cardiomyopathy

Condition:   Cardiac Amyloidosis
Intervention:  
Sponsor:   University Hospital, Grenoble
Not yet recruiting

Chart Review of Patients With COPD, Using Electronic Medical Records and Artificial Intelligence

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Other: Factors associated with Hospital admission for an Acute Exacerbation Chronic Obstructive Pulmonary Disease (AECOPD)
Sponsors:   Sociedad Española de Neumología y Cirugía Torácica;   SAVANA;   European Commission
Recruiting

COlchicine for Left VEntricular Remodeling Treatment in Acute Myocardial Infarction

Condition:   Myocardial Infarction
Interventions:   Drug: Colchicine group (experimental arm);   Drug: Placebo group (control arm)
Sponsor:   Hospices Civils de Lyon
Recruiting

Fast Track Pathway to Accelerated Cholecystectomy

Conditions:   Cholecystitis;   Cholecystectomy
Intervention:   Procedure: cholecystectomy
Sponsors:   P.J. Devereaux;   St. Joseph's Health Care London
Not yet recruiting

Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis

Condition:   Surgical Wound Infection
Interventions:   Drug: Extra dosage - cefuroxime (750mg) I.V;   Procedure: Colorectal Surgery;   Drug: Ciprofloxacin 750 mg oral;   Drug: Metronidazole 250 mg oral;   Drug: Cefuroxime 1.5 g Intravenous;   Drug: Metronidazole 1 g Intravenous
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Completed

PeriOperative ISchemic Evaluation-3 Trial

Conditions:   Perioperative Bleeding;   Venous Thrombosis;   Arterial Thrombosis
Interventions:   Drug: Tranexamic Acid;   Drug: Placebo (Saline);   Other: Perioperative hypotension-avoidance strategy;   Other: Perioperative hypertension-avoidance strategy
Sponsor:   Population Health Research Institute
Recruiting