Atrial Fibrillation Also called: AF, AFib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Validity and Reliability of the Turkish Version of Atrial Fibrillation Impact Questionnaire (AFImpact)

Condition:   Atrial Fibrillation
Intervention:   Other: Measurement of Quality of Life
Sponsors:   Bezmialem Vakif University;   Istanbul University-Cerrahpasa
Recruiting

Atrial Fibrillation Ablation Registry

Condition:   Atrial Fibrillation
Intervention:   Device: Atrial Fibrillation Ablation
Sponsor:   Hoag Memorial Hospital Presbyterian
Recruiting

Renal Function Post Cardioversion for Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Renal Insufficiency;   Cardioversion
Interventions:   Other: Electrical atrial fibrillation Cardioversion;   Other: Cardioversion
Sponsor:   Hadassah Medical Organization
Recruiting

Catheter Ablation With or Without Bariatric Surgery In Patients With Atrial Fibrillation and Morbid Obesity

Conditions:   Atrial Fibrillation;   Morbid Obesity
Interventions:   Procedure: Bariatric surgery;   Procedure: Atrial Fibrillation (AF) Catheter Ablation
Sponsor:   Stanford University
Not yet recruiting

Norwegian Study of Persistent Atrial Fibrillation Treatment: Cryoballoon Versus Radiofrequency Catheter Ablation

Condition:   Persistent Atrial Fibrillation
Interventions:   Procedure: Pulmonary vein isolation with cryoballoon catheter.;   Procedure: Pulmonary vein isolation with radiofrequency ablation.
Sponsors:   Haukeland University Hospital;   St. Olavs Hospital;   University Hospital of North Norway
Recruiting

CardioFocus vs. Contact Force Guided Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: Ablation catheter
Sponsor:   I-Med-Pro GmbH
Recruiting

A Time-to-effect Based Dosing Strategy in Cryoballoon Ablation of Patients With Paroxysmal Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Other: Conventional cryotherapy dosage;   Other: Experimental cryotherapy dosage;   Device: Arctic Front Advance ST Cryoenergy Balloon Catheter;   Drug: Adenosine triphosphate;   Device: nECG platform Nuubo®
Sponsor:   Fundación para la Investigación del Hospital Clínico de Valencia
Completed

Screening for Atrial Fibrillation (AF)-Potential Patients to Increase AF Detection Rate

Condition:   Atrial Fibrillation
Intervention:   Other: Non-interventional
Sponsor:   Bristol-Myers Squibb
Completed

First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Persistent Atrial Fibrillation Treatment (RAAFT-3)

Condition:   Atrial Fibrillation
Interventions:   Drug: Anti Arrhythmics;   Procedure: Pulmonary Vein Isolation performed by Radio Frequency Catheter Ablation
Sponsors:   University of Pennsylvania;   Biosense Webster, Inc.;   Texas Cardiac Arrhythmia Research Foundation
Recruiting

A Study to Assess the Effectiveness of an Atrial Fibrillation (AF) Risk Prediction Algorithm and Diagnostic Test in Identifying Patients With AF.

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Bristol-Myers Squibb
Recruiting

MOTIVATE AF Motivational Support for Patients With Atrial Fibrillation to Promote Weight Loss

Condition:   Atrial Fibrillation
Interventions:   Other: Weight Watchers;   Other: Slimming world;   Other: Leeds 'One You';   Other: NHS Choices;   Other: 5:2 diet;   Other: Individuals own personal plan
Sponsor:   The Leeds Teaching Hospitals NHS Trust
Not yet recruiting

Catheter Ablation of Atrial Fibrillation in Patients With Pulmonary Hypertension Hypertension: a Randomised Study

Conditions:   Atrial Fibrillation;   Pulmonary Hypertension
Intervention:   Procedure: Catheter ablation
Sponsor:   General University Hospital, Prague
Recruiting

Pulsewatch: Smartwatch Monitoring for Atrial Fibrillation After Stroke

Conditions:   Stroke;   Atrial Fibrillation
Interventions:   Device: Testing Devices;   Device: Cardea Solo by Cardiac Insight;   Device: Kardia Mobile by AliveCor
Sponsors:   University of Massachusetts, Worcester;   University of Connecticut;   Northeastern University;   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Minocycline Plus Amiodarone Versus Amiodarone Alone for the Prevention of Atrial Fibrillation After Cardiac Surgery

Condition:   Atrial Fibrillation
Interventions:   Drug: Amiodarone;   Drug: Minocycline
Sponsor:   Baystate Medical Center
Not yet recruiting

Understanding and Improving Anticoagulation Dosing for Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Duke University;   Bristol-Myers Squibb
Recruiting

Low-voltage Areas Defragmentation in Sinus Rhythm for Radiofrequency Ablation of Persistent Atrial Fibrillation

Conditions:   Cardiovascular Diseases;   Atrial Fibrillation, Persistent
Interventions:   Procedure: Isolation of pulmonary veins;   Procedure: Ablation by radiofrequency of low-voltage areas
Sponsor:   French Cardiology Society
Not yet recruiting

Effect of Renal Denervation on Atrial Fibrillation

Conditions:   Arterial Hypertension;   Atrial Fibrillation
Interventions:   Procedure: Sympathetic Renal Denervation;   Device: Implantable Loop Recorder
Sponsor:   Hippocration General Hospital
Not yet recruiting

Validation Study of a Watch for the Detection of Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Arrythmia, Cardiac
Intervention:   Diagnostic Test: AF detection by ECG
Sponsors:   Withings;   Clinact
Completed

iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology

Conditions:   Atrial Fibrillation;   Atrial Flutter
Interventions:   Device: AliveCor;   Behavioral: Behavioral Altering Messaging
Sponsor:   Columbia University
Active, not recruiting

The Maintenance of Human Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Arrhythmias, Cardiac
Intervention:  
Sponsors:   University of California, San Diego;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Study to Learn More About the Benefits and Side-effects of Drugs Rivaroxaban and Apixaban Compared to the Drug Warfarin for Stroke Prevention in Patients With Rapid and Irregular Heartbeat Which is Not Due to a Heart-valve Fault (Non-valvular Atrial Fibrillation) in the UK Routine Clinical Practice

Condition:   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Apixaban (Eliquis);   Drug: Warfarin
Sponsors:   Bayer;   Janssen, LP
Active, not recruiting

Carotid Artery Implant for Trapping Upstream Emboli for Preventing Stroke in Atrial Fibrillation Patients

Condition:   Atrial Fibrillation
Intervention:   Device: Vine™
Sponsor:   Javelin Medical
Active, not recruiting

NOACs for Stroke Prevention in Patients With Atrial Fibrillation and Previous ICH

Conditions:   Atrial Fibrillation;   Intracerebral Hemorrhage
Interventions:   Drug: NOAC;   Drug: Acetylsalicylic Acid
Sponsor:   Population Health Research Institute
Active, not recruiting

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Conditions:   Atrial Fibrillation;   Stroke;   Bleeding
Interventions:   Drug: Antiplatelet-only strategy;   Drug: Oral Anticoagulant plus background antiplatelet therapy
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   Vanderbilt University Medical Center
Not yet recruiting

Electrocardiogram Variations in the Prediction of Development of Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Hospital Italiano de Buenos Aires
Completed

Investigation of Substrates Associated With the Recurrence of Atrial Fibrillation After PV Cryoablation

Condition:   Atrial Fibrillation
Intervention:   Procedure: Cryoablation of the pulmonary veins and myocardial biopsy
Sponsors:   National Research Center for Preventive Medicine;   I.M. Sechenov First Moscow State Medical University
Recruiting

Xarelto on Prevention of Stroke and Non-Central Nervous Systemic Embolism in Renally Impaired Korean Patients With Non-valvular Atrial Fibrillation

Condition:   Non-valvular Atrial Fibrillation (NVAF)
Intervention:   Drug: Rivaroxaban(Xarelto,BAY 59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting

Intraoperative Amiodarone to Prevent Atrial Fibrillation in Lung Transplant Patients

Conditions:   Atrial Fibrillation;   Lung Transplant; Complications
Interventions:   Drug: Amiodarone with CoSeal;   Device: CO2 driver
Sponsor:   University of Louisville
Completed

Evaluation of Ambulatory ECG Telemetry for the Early Detection of Atrial Fibrillation During Hospital Assessment of Cerebral Infarction

Condition:   Cerebral Infarction
Intervention:   Device: ECG telemetry
Sponsor:   Hopital Foch
Recruiting

The Effects of Renal Function and Atrial Fibrillation on Lipoproteins and Clot Structure/Function

Conditions:   Atrial Fibrillation;   Chronic Kidney Diseases
Interventions:   Drug: Warfarin;   Drug: Statin
Sponsors:   University of Liverpool;   Liverpool Centre for Cardiovascular Science;   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Liverpool John Moores University;   University of Leeds
Not yet recruiting

Efficacy and Safety of Oral Anticoagulants Among Thai Octogenarians With Nonvalvular Atrial Fibrillation

Conditions:   Stroke;   Atrial Fibrillation
Intervention:   Drug: Non vitamin K oral anticoagulants
Sponsor:   Mahidol University
Enrolling by invitation

Dabigatran for Mitral Stenosis Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Mitral Stenosis
Interventions:   Drug: Dabigatran etexilate;   Drug: Warfarin
Sponsor:   The University of Hong Kong
Not yet recruiting

Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants

Conditions:   Atrial Fibrillation;   Stroke
Intervention:   Device: Vine™ Embolic Protection System
Sponsors:   Javelin Medical;   Genae
Recruiting

Rivaroxaban in Patients With Atrial Fibrillation Undergoing PCI

Conditions:   Non-valvular Atrial Fibrillation;   Acute Coronary Syndrome;   Percutaneous Coronary Intervention;   Antithrombotic Therapy
Intervention:  
Sponsors:   IHF GmbH - Institut für Herzinfarktforschung;   Bayer
Recruiting

Ablation STrategies for Repeat PrOcedures in Patients With Atrial Fibrillation Recurrences

Condition:   Atrial Fibrillation
Intervention:   Procedure: Catheter ablation
Sponsors:   Cardioangiologisches Centrum Bethanien;   Medtronic;   CRO Kottmann
Recruiting

Meditation and Education That is Nurse Delivered for Symptom Management in PAF

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Behavioral: Meditation;   Other: AF Education;   Other: Phone Calls
Sponsor:   Stanford University
Recruiting

INhalation of Flecainide to Convert Recent Onset SympTomatic Atrial Fibrillation to siNus rhyThm (INSTANT)

Condition:   Paroxysmal Atrial Fibrillation (PAF)
Intervention:   Drug: Flecainide Acetate
Sponsor:   InCarda Therapeutics Australia Pty Ltd.
Recruiting

'Understanding the Electrophysiological Substrate Underlying Persistent Atrial Fibrillation Study II (USURP AF- Study II)'

Conditions:   Atrial Fibrillation Mechanisms;   Persistent Atrial Fibrillation;   Substrate Ablation;   Pulmonary Vein Isolation;   Non-contact Mapping
Intervention:   Other: Catheter ablation
Sponsor:   University of Leicester
Recruiting

Autonomic Function in COPD and Risk for Atrial Fibrillation

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Other: Measurement of lung function, electrocardiography, echocardiography and autonomic function
Sponsor:   Heinrich-Heine University, Duesseldorf
Recruiting

Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial

Condition:   Ischaemic Stroke
Interventions:   Drug: Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®);   Drug: Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®)
Sponsor:   University Hospital Inselspital, Berne
Recruiting

Adherence and Coagulation Assays in Dabigatran-treated Patients With Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Medication Adherence;   Blood Coagulation Tests;   Anticoagulants; Circulating, Hemorrhagic Disorder;   Drug Effect;   Drug Use;   Drug Toxicity;   Drug Intolerance;   Blood Clot;   Blood Coagulation Disorder;   Laboratory Problem;   Bleeding;   Thrombosis
Interventions:   Other: Bloodtest;   Other: Questionnaires
Sponsors:   Hospitalsenheden Vest;   Catharina Ziekenhuis Eindhoven;   Siemens Corporation, Corporate Technology;   Diagnostica Stago;   Boehringer Ingelheim;   European Society of Cardiology;   ANIARA;   University of Aarhus;   Erasmus Medical Center
Active, not recruiting

This Study Observes the Usage of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) in Elderly Patients With a Heart Rhythm Disorder in Spain

Condition:   Atrial Fibrillation
Intervention:   Drug: Non-vitamin K antagonist oral anticoagulant
Sponsor:   Boehringer Ingelheim
Recruiting

Rivaroxaban vs Warfarin for SPAF in Multi-morbid Patients

Condition:   Nonvalvular Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Vitamin K antagonist(VKA)
Sponsor:   Bayer
Active, not recruiting

Post-approval Study of Percutaneous Left Atrial Appendage Closure ( FLAAC-2 )

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   French Cardiology Society
Recruiting

Detection of Heart Rhythm and BP With RhythmPadBP

Condition:   Atrial Fibrillation
Intervention:   Device: Device: RhythmPadBP
Sponsor:   Cardiocity Limited
Completed

Feasibility Study to Improve AF Outcomes Using a Digital Application for CV Risk Reduction

Condition:   Atrial Fibrillation
Interventions:   Behavioral: AF CARE;   Behavioral: Usual Care
Sponsors:   Stanford University;   American Heart Association;   PatientBond
Not yet recruiting

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting

Transcutaneous Autonomic Modulation in Thoracic Surgery

Conditions:   Atrial Fibrillation, Postoperative;   Postoperative Complications;   Inflammation
Interventions:   Device: Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS);   Device: Sham LLVNS
Sponsor:   Duke University
Recruiting

Optimal Antithrombotic Therapy for ACS Patients Concomitant AF Undergoing New Generation DES Implantation

Conditions:   Acute Coronary Syndrome (ACS);   Non-valvular Atrial Fibrillation (NVAF)
Interventions:   Drug: Triple antithrombotic therapy;   Drug: Dual antithrombotc therapy
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting

HeartLight Guided - Pure Pulmonary Vein Isolation Regardless of Concomitant Atrial Substrate

Condition:   Atrial Fibrillation
Intervention:   Device: PVI with HeartLight
Sponsor:   Cardioangiologisches Centrum Bethanien
Completed

Risk Factors of Outcomes Associated With Disease Progression in Patients With Atrial Fibrillation and Heart Failure (HF) Who Are Receiving a Direct Oral Anticoagulant (Rivaroxaban)

Condition:   Heart Failure
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting

Postmarket Evaluation of the Phased Radio Frequency Ablation System (GOLD AF Registry)

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Medtronic Cardiac Rhythm and Heart Failure;   IHF GmbH - Institut für Herzinfarktforschung
Completed

Left Atrial Appendage Occlusion Guided by 3D Printing

Condition:   Atrial Fibrillation
Intervention:   Procedure: 3D printing
Sponsors:   University Hospital, Montpellier;   Hôpital Privé Les Franciscaines;   Henri Mondor University Hospital;   Rangueil Hospital;   Clinique Pasteur Toulouse;   University Hospital, Bordeaux;   Clinique du Millénaire - Montpellier;   Clinique Saint Pierre - Perpignan;   Hôpital Dupuytren;   Hospital St. Joseph, Marseille, France;   European Georges Pompidou Hospital;   University Hospital, Grenoble;   University Hospital, Lille
Recruiting

Validation Study of an Advanced Blood Pressure Monitor

Conditions:   Atrial Fibrillation;   Hypertension;   Valvular Heart Disease
Interventions:   Diagnostic Test: BP measurement;   Diagnostic Test: AF detection;   Diagnostic Test: VHD detection
Sponsors:   Withings;   Clinact
Completed

Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF

Condition:   ATRIAL FIBRILLATION
Interventions:   Drug: Rivaroxaban;   Other: standard of care
Sponsors:   Montreal Heart Institute;   Canadian Stroke Prevention Intervention Network;   The Montreal Health Innovations Coordinating Center (MHICC);   Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma;   Montreal Heart Institute Foundation
Recruiting

Evaluation of New Diagnostic Methods of Cardio-embolic Related (Atrial Fibrillation) Cerebral Infarction

Condition:   Stroke
Interventions:   Procedure: MRI;   Procedure: Abdominal scanner
Sponsor:   Hopital Foch
Recruiting

This Study Looks at the Effects of Idarucizumab in Patients Who Take Dabigatran and Need Emergency Surgery or Are Bleeding

Condition:   Atrial Fibrillation
Intervention:   Drug: Idarucizumab
Sponsor:   Boehringer Ingelheim
Recruiting

Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation

Condition:   Stroke
Interventions:   Device: WATCHMAN LAAC Device Implant;   Drug: Single Antiplatelet Therapy or No Therapy (Control)
Sponsor:   Boston Scientific Corporation
Recruiting

Impact of Left Atrial Appendage Exclusion on Short-Term Clinical Outcomes and Long-Term Stroke Incidence

Conditions:   Atrial Fibrillation;   Thromboembolism;   Cerebrovascular Accident
Intervention:   Procedure: Left Atrial Appendage Ligation
Sponsors:   London Health Sciences Centre;   Ospedale San Raffaele
Completed

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Conditions:   Acute Coronary Syndrome;   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting

The ILERVAS Project: Assessing the Prevalence of Subclinical Vascular Disease and Hidden Kidney Disease

Conditions:   Atherosclerosis;   Chronic Kidney Diseases;   Metabolic Syndrome;   PreDiabetes;   Subclinical Disease and/or Syndrome
Interventions:   Diagnostic Test: Dried blood spot test;   Diagnostic Test: Urine test;   Diagnostic Test: Artery ultrasound;   Diagnostic Test: Ankle-brachial index;   Diagnostic Test: Spirometry;   Diagnostic Test: Determination of advanced glycation-end products;   Diagnostic Test: Atrial fibrillation screening;   Other: Biological sample collection;   Other: Result and recommendation report;   Diagnostic Test: Pulse wave velocity
Sponsors:   Institut de Recerca Biomèdica de Lleida;   Diputació de Lleida;   Jaume Arnó Renal Foundation;   Unit of Detection and Treatment of Atherothrombotic diseases (UDETMA);   Lleida Primary health care
Active, not recruiting

Extended ECG Monitoring in HCM Patients

Conditions:   Hypertrophic Cardiomyopathy;   Nonsustained Ventricular Tachycardia;   Ventricular Tachycardia;   Atrial Fibrillation;   Arrhythmia
Intervention:   Device: Zio XT
Sponsor:   iRhythm Technologies, Inc.
Not yet recruiting

Confirm Rx SMART Registry

Conditions:   Cardiac Arrhythmias;   Symptoms and Signs;   Atrial Fibrillation
Intervention:   Device: Confirm Rx ICM insertion procedure
Sponsor:   Abbott Medical Devices
Recruiting

Biomarkers of Acute Stroke in Clinic

Conditions:   Ischemic Stroke;   Ischemia;   Atrial Fibrillation;   Transient Ischemic Attack;   Transient Cerebrovascular Events;   Thrombotic Stroke;   Stroke;   Stroke, Acute;   Stroke, Ischemic;   Stroke, Complication;   Stroke of Basilar Artery;   Atherosclerosis;   Atheroma;   Cardioembolic Stroke;   Cardiomyopathies;   Cardiovascular Stroke;   Thromboembolism
Intervention:   Diagnostic Test: ISCDX blood test
Sponsor:   Ischemia Care LLC
Not yet recruiting

Implantable Cardiac Monitors in High-Risk Post-Infarction Patients With Cardiac Autonomic Dysfunction

Conditions:   Myocardial Infarction;   Autonomic Nervous System Diseases
Intervention:   Device: Medtronic Reveal LINQ implantable cardiac monitor
Sponsors:   Klinikum der Universitaet Muenchen;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK);   Medtronic Bakken Research Center
Recruiting

Evaluation of Ventricular Pacing Suppression Algorithms in Dual Chamber Pacemaker

Conditions:   Sick Sinus Syndrome;   Pacemaker;   Heart Failure
Interventions:   Device: Pacemaker with Fixed long AV delay;   Device: Pacemaker with VpS® algorithm on;   Device: Pacemaker with IRSplus algorithm on
Sponsors:   Keimyung University Dongsan Medical Center;   Biotronik SE & Co. KG
Recruiting

Prevention of Dysrhythmias on the Cardiac Intensive Care Unit - Does Maintenance of High-normal Serum Potassium Levels Matter

Condition:   Arrhythmias, Cardiac
Intervention:   Drug: Potassium
Sponsors:   Barts & The London NHS Trust;   London School of Hygiene and Tropical Medicine
Not yet recruiting

The Right Ventricular Pulmonary Circulation Continuum in Mitral Valve Disease Study

Conditions:   Mitral Regurgitation;   Pulmonary Hypertension
Interventions:   Diagnostic Test: Cardiac catheterisation;   Diagnostic Test: Cardiopulmonary exercise testing;   Diagnostic Test: Pulmonary function tests;   Diagnostic Test: Cardiac MRI;   Other: Quality of life survey;   Procedure: Mitral valve operation;   Procedure: Myocardial biopsies
Sponsor:   Imperial College London
Completed

Impact of Apixaban on Clinical Outcome of the Patients With Large Vessel Occlusion or Stenosis Trial

Condition:   Ischemic Stroke
Intervention:   Drug: apixisaban
Sponsor:   Hyogo College of Medicine
Completed

Coffee and Real-time Atrial and Ventricular Ectopy

Conditions:   Premature Atrial Contractions;   Premature Ventricular Contractions
Interventions:   Behavioral: Start: On Caffeine;   Behavioral: Start: Off Caffeine
Sponsor:   University of California, San Francisco
Recruiting

Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis

Conditions:   Symptomatic Aortic Stenosis;   Eligible for Transcatheter Aortic Valve Replacement
Interventions:   Drug: Apixaban;   Drug: Standard of care
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Action Research Group;   Bristol-Meyers Squibb & Pfizer
Active, not recruiting

Apixaban Versus Warfarin in Patients With Left Ventricular (LV) Thrombus

Conditions:   Acute Myocardial Infarction;   Left Ventricular Thrombosis;   Anticoagulants and Bleeding Disorders
Interventions:   Drug: Apixaban Oral Tablet [Eliquis];   Drug: Warfarin
Sponsor:   Hadassah Medical Organization
Recruiting

Daily Ambulatory Remote Monitoring System For Post-Dischage Management Of ADHF

Condition:   Heart Failure With Reduced Ejection Fraction
Interventions:   Procedure: Home-based remote heart failure management;   Procedure: Home-based physiological parameter recording only
Sponsors:   The University of Hong Kong;   Chinese University of Hong Kong;   Novartis Pharmaceuticals
Not yet recruiting

ReachPR Trial Resynchronization Therapy in Heart Failure Patients With Prolonged PR Interval

Conditions:   Atrioventricular Dyssynchrony;   Heart Failure
Intervention:   Device: Cardiac resynchronization therapy
Sponsor:   Maastricht University Medical Center
Recruiting

Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care

Conditions:   Diabetes Mellitus;   Hypertension;   Coronary Artery Disease;   Atrial Fibrillation;   Stroke
Interventions:   Other: PHCVRS Intervention;   Other: Personal Health Record
Sponsor:   Korey Kennelty
Completed

LEft VEntricuLar Activation Time Shortening With Hisian Pacing vs Biventricular Resinchronization Therapy

Conditions:   His Bundle Pacing;   Resynchronization Therapy
Interventions:   Device: Lead placed in the His bundle in order to achieve QRS shortening.;   Device: Lead is placed in a tributary of the coronary sinus.
Sponsors:   Josep Lluis Mont Girbau;   Institut d'Investigacions Biomèdiques August Pi i Sunyer;   Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV)
Not yet recruiting

Cardiovascular Events in Chronic Obstructive Pulmonary Disease Patients Initiating Olodaterol or Other Long-acting beta2 Agonists

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting

Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft Surgery

Conditions:   Coronary Artery Bypass;   Antiplatelet Agents
Interventions:   Drug: Aspirin;   Drug: Ticagrelor
Sponsor:   Ruijin Hospital
Completed

Home Hospital for Suddenly Ill Adults

Conditions:   Infection;   Heart Failure;   COPD;   Asthma;   Gout Flare;   Chronic Kidney Diseases;   Hypertensive Urgency;   Atrial Fibrillation Rapid;   Anticoagulants; Increased
Intervention:   Other: Home Hospitalization
Sponsor:   Brigham and Women's Hospital
Recruiting

Diet and Exercise Frailty Intervention in Cardiac Device Patients

Conditions:   Frailty;   Cardiovascular Diseases
Intervention:   Other: Exercise and Nutritional Supplement
Sponsor:   Population Health Research Institute
Not yet recruiting

AntiCoagulation Tracking InterVention and Evaluation

Conditions:   Anticoagulation;   Atrial Fibrillation;   Atrial Flutter;   Pulmonary Embolus/Emboli;   Deep Vein Thrombosis;   Stroke;   Hypercoagulability
Interventions:   Other: Panel Management for Anticoagulation Therapy;   Other: Usual Care
Sponsor:   University of California, San Francisco
Not yet recruiting

A Study of ISIS 416858 Administered Subcutaneously to Patients With End-Stage Renal Disease on Hemodialysis

Condition:   End-stage Renal Disease (ESRD)
Interventions:   Drug: ISIS 416858;   Drug: Placebo
Sponsors:   Ionis Pharmaceuticals, Inc.;   Bayer
Completed

Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)

Condition:   Reversal of Neuromuscular Blockade
Interventions:   Drug: Sugammadex 2 mg/kg;   Drug: Sugammadex 4 mg/kg;   Drug: Sugammadex 16 mg/kg;   Drug: Neostigmine + Glycopyrrolate
Sponsor:   Merck Sharp & Dohme Corp.
Recruiting

Comparison of Minimal Versus Conventional Extracorporeal Circulation in Coronary Surgery

Condition:   Coronary Artery Bypass
Interventions:   Procedure: Coronary artery bypass grafting with the use of minimal invasive extracorporeal circulation;   Procedure: Coronary artery bypass grafting under conventional extracorporeal circulation
Sponsor:   AHEPA University Hospital
Active, not recruiting

Association of PeriOPerative Aspirin-ResisTance and CardioVascular Outcome

Condition:   Myocardial Injury
Intervention:  
Sponsor:   University Hospital Heidelberg
Not yet recruiting

Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy

Conditions:   Postpartum Hemorrhage;   Twin
Intervention:   Drug: Oxytocin
Sponsor:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting

Carbetocin vs. Oxytocin at Elective Cesarean Section

Condition:   Postpartum Hemorrhage
Interventions:   Drug: Carbetocin;   Drug: Oxytocin
Sponsor:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Recruiting

Rest Ventilatory Parameters Predict Morbidity and Mortality in Thoracic Surgery

Conditions:   Pulmonary Complication;   Cardiovascular Complication
Intervention:   Procedure: Thoracic surgery
Sponsor:   St. Anne's University Hospital Brno, Czech Republic
Recruiting

Efficacy and Safety of Selonsertib in Participants With Moderate to Advanced Diabetic Kidney Disease

Condition:   Diabetic Kidney Disease
Interventions:   Drug: SEL;   Drug: Placebo
Sponsor:   Gilead Sciences
Recruiting

Prehospital Non-invasive Cooling of Comatose Patients After Cardiac Arrest

Conditions:   Cardiac Arrest;   Postresuscitation Encephalopathy
Intervention:   Device: CAERVest cooling device
Sponsors:   Medical University of Vienna;   Bodychillz Ltd
Not yet recruiting

Starch or Saline After Cardiac Surgery

Condition:   Coronary Artery Bypass Surgery
Interventions:   Drug: 6% Hydroxyethyl Starch 130/0.4;   Drug: 0.9% Normal Saline
Sponsor:   London Health Sciences Centre
Terminated

Low INR to Minimize Bleeding With Mechanical Valves Trial

Conditions:   Bleeding Post-mechanical Valve Replacement;   Thromboembolism Post-mechanical Valve Replacement
Intervention:   Drug: Warfarin
Sponsor:   McMaster University
Not yet recruiting

Real-world Use and Prognosis of Beta Blocker in Patients With Acute Coronary Syndrome in the Central China

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Henan Institute of Cardiovascular Epidemiology
Recruiting

Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve Replacement (REPRISE Japan)

Condition:   Aortic Stenosis
Intervention:   Device: Lotus Valve System
Sponsor:   Boston Scientific Corporation
Active, not recruiting

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