Atrial Fibrillation Also called: AF, AFib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Real-World Comparison of Safety and Effectiveness of Novel Oral Anti-Coagulant (NOAC) Naïve and Warfarin Naïve Non-Valvular Atrial Fibrillation (NVAF) Patients With Medicare Advantage Coverage

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Dabigatran;   Drug: Rivaroxaban;   Drug: Warfarin
Sponsor:   Bristol-Myers Squibb
Completed - verified June 2017

Assessment of The Effect of Apixaban in AF

Conditions:   Atrial Fibrillation;   Embolism Thrombosis
Intervention:   Other: Thrombin generation assays, Thromboelastography (TEG), and Global Thrombosis Test (GTT)
Sponsors:   East and North Hertfordshire NHS Trust;   University of Hertfordshire;   BMS/Pfizer European Thrombosis Investigator Initiated Research Program;   Sandwell and West Birmingham Hospitals NHS Trust
Not yet recruiting - verified June 2017

Atrial Fibrillation Research In CATalonia

Conditions:   Arrhythmia Atrial;   Atrial Fibrillation;   Hypertension;   Diabetes Mellitus
Intervention:  
Sponsors:   Jordi Gol i Gurina Foundation;   Fundación Pública Andaluza para la gestión de la Investigación en Sevilla;   Fundació La Marató de TV3;   Laboratorio de Investigación Neurovascular Institut de Recerca, Hospital Vall d'Hebron, Barcelona
Active, not recruiting - verified June 2017

Detection of Atrial Fibrillation in the Hospital Setting by Use of a Handheld ECG Recording Device

Condition:   Atrial Fibrillation
Intervention:   Device: Zenicor ECG
Sponsor:   Stéphane Cook, Prof
Not yet recruiting - verified June 2017

Safety and Feasibility of Electrical Isolation of the Superior Vena Cava for Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: SVC isolation
Sponsor:   Ettore Sansavini Health Science Foundation
Recruiting - verified June 2017

Conventional Versus RF Needle Transseptal Puncture for Cryoballoon Ablation

Condition:   Atrial Fibrillation
Interventions:   Device: Baylis transseptal system group;   Device: Standard conventional transseptal group
Sponsors:   Jason Andrade;   Baylis Medical Company
Recruiting - verified June 2017

Characterization of Heart Failure With Preserved Ejection Fraction

Condition:   Fibrosis Estimated by cMR Ant Biomarkers
Interventions:   Diagnostic Test: cMR;   Biological: biomarker
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Recruiting - verified June 2017

E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF

Conditions:   Simulation Training;   Anticoagulant Drugs;   Elderly;   Atrial Fibrillation;   Drug Prescriptions;   Internal Medicine;   Geriatrics
Interventions:   Other: E-learning educational program;   Other: Control
Sponsor:   Mario Negri Institute for Pharmacological Research
Active, not recruiting - verified June 2017

Comparison of the Efficacy of Rivroxaban to Coumadin( Warfarin ) in Cerebral Venous Thrombosis

Condition:   Cerebral Venous Thrombosis
Interventions:   Drug: Coumadin;   Drug: Rivoroxaban
Sponsors:   Foundation University Islamabad;   Shaheed Zulfiqar Ali Bhutto University, Pakistan Institute of Medical Sciences, College of Physicians and Surgeons Pakistan
Not yet recruiting - verified June 2017

Japanese Pradaxa PMS, Long Term

Condition:   Atrial Fibrillation
Intervention:   Drug: Prazaxa Capsules
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified June 2017

The Efficacy of Single Coil Defibrillation Leads for Internal Cardioversion of Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Internal Cardioversion;   Procedure: External Cardioversion
Sponsor:   University of Kentucky
Recruiting - verified June 2017

Bleeding Risk Evaluation in Haemophilia Patients Under Antiplatelet Therapies

Condition:   Hemophilia
Intervention:   Other: Non interventional study
Sponsor:   Nantes University Hospital
Not yet recruiting - verified May 2017

Pilot Study for the Tight K Study

Condition:   Cardiac Arrythmias
Intervention:   Drug: Potassium
Sponsors:   Queen Mary University of London;   London School of Hygiene and Tropical Medicine
Not yet recruiting - verified March 2017

Use of Direct Oral Anticoagulants in UK

Condition:   Stroke
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Dabigatran;   Drug: Apixaban
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Active, not recruiting - verified June 2017

Impact of Empaglifozine on Cardiac Ectopic Fat

Condition:   Type 2 Diabetes
Intervention:   Drug: Empagliflozin 10Mg Tab
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified June 2017

Computer Simulated Atrial Fibrillation Tool

Condition:   Atrial Fibrillation
Intervention:   Other: Virtual Platform
Sponsors:   Nova Scotia Health Authority;   Cardiac Arrhythmia Network of Canada
Not yet recruiting - verified June 2017

Repetitive Activation Patterns and Focal Impulses Identification and Ablation in Persistent AF

Condition:   Persistent Atrial Fibrillation
Intervention:   Procedure: cartofinder guided ablation followed by PVI
Sponsor:   Biosense Webster, Inc.
Recruiting - verified June 2017

Evaluation of Ablation Index and VISITAG™ (ABI-173)

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: RF ablation
Sponsor:   Biosense Webster, Inc.
Recruiting - verified June 2017

Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation

Condition:   Stroke
Intervention:   Other: Time-To-Treatment Randomization
Sponsors:   University of Texas at Austin;   Lone Star Stroke Research Consortium;   Texas Department of State Health Services
Recruiting - verified June 2017

FIND CAN Trial: "CF-172"

Condition:   Persistent Atrial Fibrillation
Intervention:   Device: Ablation procedure
Sponsor:   Biosense Webster, Inc.
Recruiting - verified June 2017

Comparison Between One-stop Hybrid Ablation and Thoracoscopic Surgical Ablation for Refactory Atrial Fibrillation

Condition:   Persistent Atrial Fibrillation
Interventions:   Procedure: Hybrid ablation;   Procedure: Thoracoscopic surgical ablation
Sponsor:   China National Center for Cardiovascular Diseases
Recruiting - verified June 2017

Evaluation of a Multi-electrode Linear Type Catheter (D-1368-01-SI)

Condition:   Persistent Atrial Fibrillation
Intervention:   Device: Endocardial Ablation Procedure
Sponsor:   Biosense Webster, Inc.
Recruiting - verified June 2017

SmartWATCHes for Detection of Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Device: Five minutes pulse wave recording
Sponsors:   University Hospital, Basel, Switzerland;   University Hospital Greifswald
Recruiting - verified June 2017

Enhanced Diagnostics for Early Detection of Atrial Fibrillation - Prospective Validation

Conditions:   Atrium; Fibrillation;   Arrhythmia Atrial
Intervention:   Device: Five minutes puls wave recording
Sponsors:   University Hospital, Basel, Switzerland;   University Hospital Greifswald
Recruiting - verified June 2017

Clinical Study for Workflow and Performance Evaluation of the THERMOCOOL SMARTTOUCH® SF-5D System for Treating Symptomatic Paroxysmal AF (QDOT-Micro)

Condition:   Atrial Fibrillation
Intervention:   Device: THERMOCOOL SMARTTOUCH® SF-5D catheter
Sponsor:   Biosense Webster, Inc.
Recruiting - verified June 2017

A Digital Non-interventional Atrial Fibrillation (AF) Screening Study With Commercial Pulse Detection Systems

Condition:   Atrial Fibrillation
Interventions:   Device: 12-point-ECG;   Device: Polar V800;   Device: 360° eMotion FAROS SET + Belt;   Device: Adidas Micoach smart run;   Device: TomTom Runner Cardio;   Device: TomTom Runner Cardio HRM
Sponsor:   Bayer
Not yet recruiting - verified June 2017

Xarelto Evidence in Real Life of Patients' Preference and Satisfaction Study

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified June 2017

Sub-Clinical Atrial Fibrillation Biomarker Study

Condition:   Subclinical Atrial Fibrillation
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Population Health Research Institute;   Genome Canada
Recruiting - verified June 2017

Review of the Safety and Effectiveness of the THERMOCOOL SMARTTOUCH® SF Catheter Evaluated for Treating Symptomatic PersistenT AF (PRECEPT)

Condition:   Atrial Fibrillation
Intervention:   Device: THERMOCOOL SMARTTOUCH® SF catheter
Sponsor:   Biosense Webster, Inc.
Recruiting - verified June 2017

Treatment Convenience in Patients Treated With Dabigatran for Stroke Prophylaxis in Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2017

Feasibility of Perioperative Stellate Ganglion Blocks in Cardiac Surgery

Condition:   Atrial Fibrillation
Intervention:   Procedure: Stellate Ganglion Block
Sponsor:   Christopher Connors, MD
Completed - verified June 2017

Amiodarone and N-Acetylcysteine or Amiodarone Alone for Preventing Atrial Fibrillation After Thoracic Surgery

Conditions:   Thoracic Surgery;   Atrial Fibrillation in High Risk Patients
Interventions:   Drug: Amiodarone;   Drug: N-Acetylcysteine;   Drug: Placebo
Sponsors:   Memorial Sloan Kettering Cancer Center;   Washington University School of Medicine;   The Cleveland Clinic;   Vanderbilt University School of Medicine
Recruiting - verified June 2017

CAPA-VU Trial Catheter Ablation in Paroxymal Atrial Fibrillation Based on UNIVU

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Procedure: CartoUnivu™;   Procedure: Ablation with Carto® 3 System
Sponsors:   Universitätsklinikum Hamburg-Eppendorf;   Biosense Webster, Inc.
Recruiting - verified June 2017

FIRM Ablation Versus Pulmonary Vein Isolation for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Procedure: FIRM-guided RF ablation;   Procedure: Conventional RF ablation
Sponsor:   Abbott Electrophysiology
Recruiting - verified June 2017

AtriClip® Left Atrial Appendage Exclusion Concomitant to Structural Heart Procedures (ATLAS)

Condition:   Post-Operative Atrial Fibrillation
Interventions:   Device: AtriClip® Gillinov-Cosgrove™ LAA Exclusion Systems;   Drug: Anticoagulation Therapy
Sponsor:   AtriCure, Inc.
Recruiting - verified April 2017

Left Atrial Appendage Occlusion Registry (LAAO Registry)

Condition:   Atrial Fibrillation
Intervention:   Procedure: Left Atrial Appendage Occlusion
Sponsor:   American College of Cardiology
Recruiting - verified June 2017

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Completed - verified June 2017

Exercise Training in Patients With Atrial Fibrillation (OPPORTUNITY Study)

Condition:   Atrial Fibrillation
Interventions:   Behavioral: moderate-intensity continuous exercise training;   Behavioral: high-intensity interval training
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting - verified June 2017

Feasibility Study of a Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Device: Aegis Sierra Ligation System
Sponsors:   Aegis Medical Innovations;   Applied Health Research Centre
Recruiting - verified June 2017

mHealth Screening to Prevent Strokes

Condition:   Atrial Fibrillation
Interventions:   Device: iRhythm ZIO XT Patch;   Device: Wristband by Amiigo
Sponsors:   Scripps Translational Science Institute;   Janssen Scientific Affairs, LLC;   Aetna, Inc.
Active, not recruiting - verified June 2017

Temporary Autonomic Blockade to Prevent Atrial Fibrillation After Cardiac Surgery

Condition:   Atrial Fibrillation
Interventions:   Drug: Botulinum Toxin Type A;   Drug: Placebo
Sponsors:   Joseph Mathew, M.D.;   Foundation for Anesthesia Education and Research;   American Heart Association
Recruiting - verified June 2017

SMART China, A Multi-center Clinical Registry Study

Condition:   Atrial Fibrillation
Intervention:   Device: THERMOCOOL® SMARTTOUCH™
Sponsor:   Biosense Webster, Inc.
Active, not recruiting - verified June 2017

LAA Excision With AF Ablation Versus Oral Anticoagulants for Secondary Prevention of Stroke

Conditions:   Atrial Fibrillation;   Stroke;   Systemic Embolism
Interventions:   Procedure: Thoracoscopic LAA Excision plus AF Ablation;   Drug: Warfarin or Novel Oral Anticoagulants
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified June 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified June 2017

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified June 2017

Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach

Conditions:   Atrial Fibrillation;   Persistent or Longstanding Persistent Atrial Fibrillation
Intervention:   Device: AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation
Sponsor:   AtriCure, Inc.
Suspended - verified November 2016

Comparison of Accidents and Their Circumstances With Oral Anticoagulants

Conditions:   Cardiovascular Complications;   Hemorrhagic Disorders;   Embolism and Thrombosis
Intervention:   Other: Follow up
Sponsors:   CNGE IRMG Association;   Floralis;   University Hospital, Grenoble
Completed - verified June 2017

Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke

Condition:   Ischemic Stroke
Intervention:   Device: Reveal LINQ Insertable Cardiac Monitor
Sponsor:   Northwell Health
Active, not recruiting - verified June 2017

Compare the Efficacy of Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft Surgery

Conditions:   Coronary Artery Bypass;   Antiplatelet Agents
Interventions:   Drug: Aspirin;   Drug: Ticagrelor
Sponsor:   Ruijin Hospital
Active, not recruiting - verified June 2017

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

Condition:   Persistent Atrial Fibrillation
Interventions:   Device: Convergent Procedure EPi-Sense-AF Guided Coagulation System;   Device: Endocardial Catheter Ablation
Sponsor:   AtriCure, Inc.
Recruiting - verified April 2017

Registry on WATCHMAN Outcomes in Real-Life Utilization WASP Registry

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified June 2017

Oral Anticoagulation Therapy Pilot Study

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Other: Off OAT Group (Test);   Other: On OAT Group (Control)
Sponsor:   Biosense Webster, Inc.
Recruiting - verified June 2017

Cryoballoon vs. Irrigated Radiofrequency Catheter Ablation: Double Short vs. Standard Exposure Duration

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: Pulmonary Vein Isolation
Sponsor:   University of British Columbia
Active, not recruiting - verified June 2017

Eliquis Regulatory Post Marketing Surveillance

Condition:   NonValvular Atrial Fibrillation
Intervention:   Drug: Apixaban
Sponsor:   Bristol-Myers Squibb
Active, not recruiting - verified June 2017

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Completed - verified June 2017

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa (Dabigatran etexilate mesilate)
Sponsor:   Boehringer Ingelheim
Completed - verified June 2017

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2017

Atrial Fibrillation Progression Trial

Condition:   Atrial Fibrillation
Interventions:   Device: Catheter Ablation;   Drug: Drug Treatment
Sponsor:   Biosense Webster, Inc.
Recruiting - verified June 2017

Rhythm Control - Catheter Ablation With or Without Anti-arrhythmic Drug Control of Maintaining Sinus Rhythm Versus Rate Control With Medical Therapy and/or Atrio-ventricular Junction Ablation and Pacemaker Treatment for Atrial Fibrillation

Conditions:   Heart Failure;   Atrial Fibrillation
Interventions:   Procedure: Rhythm control;   Other: Rate Control
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR)
Recruiting - verified June 2017

Bazedoxifene Post Approval Safety Study (PASS) in the European Union (EU)

Condition:   Osteoporosis, Postmenopausal
Interventions:   Drug: Bazedoxifene;   Drug: Bisphosphonate;   Drug: Raloxifene
Sponsor:   Pfizer
Active, not recruiting - verified June 2017

Atrial Substrate Modification With Aggressive Blood Pressure Lowering to Prevent AF

Condition:   Atrial Fibrillation
Intervention:   Drug: Aggressive Blood Pressure control
Sponsors:   Nova Scotia Health Authority;   Nova Scotia Health Research Foundation
Completed - verified June 2017

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