Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Evaluation of Conventional Ablation With or Without Focal Impulse and Rotor Modulation to Eliminate Human AF

Condition:   Atrial Fibrillation
Interventions:   Procedure: Conventional AF Ablation with PVI;   Procedure: FIRM-guided ablation plus PVI
Sponsor:   Stanford University
Not yet recruiting - verified May 2015

Evaluate the Safety and Efficacy of Vanoxerine for the Conversion of Subjects With Recent Onset Atrial Fibrillation or Flutter to Normal Sinus Rhythm

Condition:   Atrial Fibrillation or Flutter
Interventions:   Drug: Vanoxerine HCl;   Drug: Placebo
Sponsor:   Laguna Pharmaceuticals, Inc.
Not yet recruiting - verified May 2015

Coagulation Activity and Thrombogenesis in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: circumferential ablation;   Device: SVT ablation
Sponsor:   Tel-Aviv Sourasky Medical Center
Not yet recruiting - verified May 2015

Apixaban in Patients Who Undergo CIED Procedure- Randomized Pilot Study

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Warfarin
Sponsors:   Mayo Clinic;   Bristol-Myers Squibb
Not yet recruiting - verified May 2015

Electronic Warning System for Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Other: Electronic warning alert
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified May 2015

Hybrid Versus Catheter Ablation in Persistent AF

Condition:   Atrial Fibrillation
Interventions:   Procedure: Hybrid Ablation;   Procedure: Catheter Ablation
Sponsors:   Maastricht University Medical Center;   AtriCure, Inc.
Not yet recruiting - verified May 2015

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Recruiting - verified May 2015

Pulmonary Artery Harmonic Ace+7 Energy Sealing in Open Lobectomy

Condition:   Lung Cancer
Intervention:   Device: HARMONIC ACE+7
Sponsors:   Centre hospitalier de l'Université de Montréal (CHUM);   Centre de Recherche du Centre Hospitalier de l'Université de Montréal;   Ethicon Endo-Surgery
Not yet recruiting - verified May 2015

Cost of Monitoring Patients Treated With Vitamin K Antagonists in Spain

Condition:   Anticoagulation
Intervention:  
Sponsors:   Bristol-Myers Squibb;   Badalona Serveis Assistencial ;   IMS Health
Active, not recruiting - verified May 2015

Effectiveness of Ripple Mapping in Atrial Tachycardia Ablation

Condition:   Atrial Tachycardia
Interventions:   Device: Ripple Mapping guided AT ablation;   Device: Conventional AT ablation
Sponsor:   Imperial College London
Not yet recruiting - verified March 2015

Evaluation the Effectiveness of the Risk Minimisation Activities in the Treatment of Stroke Prevention in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2015

Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach

Conditions:   Atrial Fibrillation;   Persistent or Longstanding Persistent Atrial Fibrillation
Intervention:   Device: AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation
Sponsor:   AtriCure, Inc.
Recruiting - verified April 2015

Validation of Ambulatory Sleep Test (WP200/U) Compared In-lab Sleep Testing in Cardiac Subjects

Condition:   Sleep Disorders
Intervention:  
Sponsor:   Itamar-Medical, Israel
Recruiting - verified May 2015

Uninterrupted Dabigatran Etexilate in Comparison to Uninterrupted Warfarin in Pulmonary Vein Ablation (RE-CIRCUIT)

Condition:   Atrial Fibrillation
Interventions:   Drug: Warfarin;   Drug: Dabigatran Etexilate 150mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2015

Reduction of AF Ablation Induced Thrombo-Embolic Incidence Pilot Study

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Device: Cerebral Diffusion-Weighted Magnetic Resonance Imaging;   Device: Transesophageal Echocardiography;   Other: Paperbased neurocognitive testing
Sponsor:   Biotronik SE & Co. KG
Recruiting - verified May 2015

Origin of Premature Atrial Beats Induced by Simulated Obstructive Sleep Apnea

Conditions:   Atrial Fibrillation;   Sleep Apnea, Obstructive;   Atrial Premature Complexes
Intervention:   Procedure: Standard pulmonary vein isolation
Sponsor:   University of Zurich
Recruiting - verified May 2015

Observational Study to Assess Sociodemographic and Clinical Features of Patients Treated With Rivaroxaban in Routine Clinical Practice of Hematologists, Cardiologists and Internists of Spain

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Completed - verified May 2015

Program for the Identification of "Actionable" Atrial Fibrillation in the Family Practice Setting

Condition:   Atrial Fibrillation
Interventions:   Other: 30 Second Pulse Check;   Device: Watch BP Home A;   Device: HeartCheck Hand-held ECG device
Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified May 2015

Role of Cardiac Biomarkers in Prediction of Outcome in Atrial Fibrillation Patients Undergoing Catheter Ablation

Condition:   Atrial Fibrillation
Intervention:   Procedure: Radio-frequency catheter ablation
Sponsor:   Texas Cardiac Arrhythmia Research Foundation
Active, not recruiting - verified May 2015

Cologne Cardioversion Study

Conditions:   Atrial Arrhythmia;   Heart Failure
Interventions:   Device: Internal Electrocardioversion;   Device: External Electrocardioversion
Sponsors:   Universitätsklinikum Köln ;   Medtronic;   St. Jude Medical
Recruiting - verified May 2015

Efficacy, Safety and Efficiency of the nMARQ Pulmonary Vein Isolation System in Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: ablation
Sponsors:   Basildon and Thurrock University Hospitals NHS Foundation Trust;   Anglia Ruskin University
Recruiting - verified May 2015

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Recruiting - verified April 2015

Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Hypertension
Interventions:   Drug: Renal nerve denervation;   Device: Cryoablation
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified May 2015

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified May 2015

Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in Europe

Conditions:   Coronary Artery Disease;   Myocardial Infarction;   Dilated Cardiomyopathy;   Implantable Defibrillator User
Intervention:  
Sponsor:   University Medical Center Goettingen
Recruiting - verified May 2015

Cognitive Impairment Related to Atrial Fibrillation Prevention Trial

Condition:   Atrial Fibrillation
Interventions:   Drug: Warfarin;   Drug: Dabigatran
Sponsors:   University of Sao Paulo;   Federal University of Minas Gerais;   Boehringer Ingelheim
Recruiting - verified May 2015

Effect of Cavotricuspid Isthmus Ablation in Patients Without History of Typical Flutter During Ablation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Procedure: cavotricuspid isthmus ablation;   Procedure: control group
Sponsor:   Seoul St. Mary's Hospital
Recruiting - verified May 2015

Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Drug: Apixaban;   Drug: aspirin
Sponsors:   Population Health Research Institute;   Bristol-Myers Squibb;   Pfizer;   Medtronic
Recruiting - verified May 2015

Randomized Comparison of Continuous and Intermittent Heparin Infusion During Catheter Ablation of Atrial Fibrillation

Condition:   Coagulation; Intravascular
Interventions:   Drug: Continuous heparin infusion;   Drug: Intermittent heparin infusion
Sponsor:   Seoul St. Mary's Hospital
Recruiting - verified May 2015

Risk of Stroke and Silent Cerebrovascular Thromboembolism After Cardioversion of Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Cardioversion;   Cerebrovascular Stroke
Interventions:   Procedure: Cardioversion;   Drug: warfarin
Sponsor:   Suleyman Demirel University
Recruiting - verified October 2014

Cryoballoon vs. Irrigated Radiofrequency Catheter Ablation: Double Short vs. Standard Exposure Duration

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: Pulmonary Vein Isolation
Sponsor:   University of British Columbia
Recruiting - verified May 2015

A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurrence

Conditions:   Persistent Atrial Fibrillation;   Paroxysmal Atrial Fibrillation;   Hypertension;   Renal Denervation;   Cardiac Ablation
Interventions:   Device: Renal Artery Ablation Catheter;   Device: Cardiac Ablation
Sponsor:   St. Jude Medical
Recruiting - verified May 2015

Non-interventional Local Study on Prescription Behavior of Anticoagulation Therapy in Secondary Stroke Prevention in Atrial Fibrillation Patients

Conditions:   Stroke,;   Embolism
Intervention:   Other: Rivaroxaban ( Xarelto, BAY59-7939)
Sponsor:   Bayer
Active, not recruiting - verified May 2015

Pradaxa Study in Non-valvular Atrial Fibrillation Patients With Severely Impaired Renal Function

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa, dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2015

Impact of the Pulmonary Vein Isolation on Exercise Capacity in Patients With Chronic Atrial Fibrillation

Condition:   Chronic Atrial Fibrillation
Intervention:   Procedure: Radiofrequency catheter ablation
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   University of Texas at Austin
Recruiting - verified May 2015

Assessment of an Education and Guidance Programme for Eliquis Adherence in Non-Valvular Atrial Fibrillation (AEGEAN)

Condition:   Non-valvular Atrial Fibrillation
Intervention:   Drug: Apixaban
Sponsor:   Bristol-Myers Squibb
Recruiting - verified December 2014

A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: rivaroxaban 2.5 mg;   Drug: rivaroxaban 15 mg;   Drug: rivaroxaban 10 mg;   Drug: aspirin (ASA);   Drug: vitamin K antagonist (VKA);   Drug: clopidogrel;   Drug: prasugrel;   Drug: ticagrelor
Sponsors:   Janssen Scientific Affairs, LLC;   Bayer
Recruiting - verified May 2015

The Concomitant Cryomaze Procedure Using Nitreous Oxide Cryoprobe: Comparison With Argon Based Cryoprobe

Conditions:   Atrial Fibrillation;   Valve
Interventions:   Device: Cryomaze procedure using Nitrous oxide;   Device: Cryomaze procedure using Argon
Sponsor:   Samsung Medical Center
Recruiting - verified March 2013

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Asia

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified May 2015

Multi-electrode PulmonarY Vein Isolation Versus Single Tip Wide Area Catheter Ablation for Paroxysmal Atrial Fibrillation (PAF)

Condition:   Atrial Fibrillation
Intervention:   Device: Cardiac ablation for Atrial Fibrillation
Sponsor:   L.V.A. Boersma
Completed - verified May 2015

Does Atrial Fibrillation (AF) Termination Without Additional Ablation Influence Outcome?

Condition:   Atrial Fibrillation
Interventions:   Procedure: PVAI;   Procedure: PVAI + ablation of extraPV triggers
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   California Pacific Medical Center
Recruiting - verified May 2015

Pulmonary Vein Antrum Isolation (PVAI) Plus Isolation of Complex Fractionated Atrial Electrograms (CAFE) and Non-PV Triggers Ensure Long-term Recurrence-free Survival in Non-paroxysmal Atrial Fibrillation

Conditions:   Persistent Atrial Fibrillation;   Long-standing Persistent Atrial Fibrillation
Interventions:   Procedure: Pulmonary Vein Antrum Isolation;   Procedure: CFAE ablation;   Procedure: Isolation of non-PV triggers
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   California Pacific Medical Center
Recruiting - verified May 2015

PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: PVAI followed by adenosine provocation
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   California Pacific Medical Center
Recruiting - verified May 2015

Outcome of Atrial Fibrillation Ablation After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Pulmonary vein antrum isolation (PVAI);   Procedure: PVAI plus left atrial posterior wall (LAPW) isolation
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   Centro Cardiologico Monzino;   Catholic University of the Sacred Heart;   Capital Medical University
Recruiting - verified May 2015

Comparison of Treatment of Atrial Fibrillation (AF) Between Surgical Ultrasonic Technology or Drug Therapy for Patients With AF Requiring Mitral Valve Surgery

Conditions:   Mitral Valvulopathy;   Atrial Fibrillation
Interventions:   Device: EPICOR;   Drug: Amiodarone
Sponsors:   Centre Hospitalier Universitaire de Saint Etienne;   Ministry of Health, France
Recruiting - verified May 2015

Antazoline in Rapid Cardioversion of Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: antazoline;   Drug: 0.9% saline
Sponsor:   Institute of Cardiology, Warsaw, Poland
Completed - verified May 2015

Variant of Stimulation in Atrioventricular Node Ablation (VISTA) in Patients With Atrial Fibrillation and Moderate Chronic Heart Failure

Condition:   Heart Failure
Interventions:   Device: Implantation of CRT device;   Device: Implantation of conventional VVI(R) pacemaker
Sponsor:   Federal North-West Medical Research Centre
Recruiting - verified January 2014

Syncope: Pacing or Recording in the Later Years

Conditions:   Syncope;   Heart Block;   Conduction Disorder of the Heart
Interventions:   Procedure: pacemaker;   Procedure: implantable loop recorder
Sponsors:   Canadian Institutes of Health Research  (CIHR);   Vanderbilt University
Active, not recruiting - verified May 2015

Effect of Catheter Ablation on Clinical Course of Migraine in AF Patients With or Without Previous History of Migraine

Conditions:   Migraine;   Atrial Fibrillation
Interventions:   Procedure: Radiofrequency catheter ablation;   Procedure: Radiofrequency catheter ablation
Sponsor:   Texas Cardiac Arrhythmia Research Foundation
Recruiting - verified May 2015

Study of the Wearable Defibrillator in Heart-Failure Patients

Conditions:   Heart Failure;   Ventricular Dysfunction;   Sudden Death;   Sudden Cardiac Arrest;   Ventricular Tachycardia;   Ventricular Fibrillation
Intervention:   Device: wearable defibrillator (LifeVest)
Sponsor:   Zoll Medical Corporation
Active, not recruiting - verified December 2014

The Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis Pilot Study (The POSEIDON-Pilot Study)

Condition:   Stem Cell Transplantation
Interventions:   Biological: Auto-hMSCs;   Biological: Allo-hMSCs
Sponsors:   University of Miami;   National Heart, Lung, and Blood Institute (NHLBI);   The EMMES Corporation
Completed - verified May 2015

INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery

Condition:   Systemic Inflammatory Response Syndrome
Intervention:   Procedure: cardiac surgery with CPB use
Sponsors:   Medical University of Gdansk;   Ministry of Science and Higher Education, Poland
Completed - verified May 2015

Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation

Condition:   Thromboembolism
Interventions:   Drug: Coumadin;   Drug: Coumadin;   Drug: Coumadin
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   University of Kansas;   California Pacific Medical Center;   Stanford University;   Case Western Reserve University;   Southlake Regional Health Centre;   Catholic University, Italy
Completed - verified May 2015

Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD

Condition:   Heart Failure
Interventions:   Procedure: Atrial Fibrillation ablation;   Drug: Amiodarone
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   Casa Sollievo della Sofferenza IRCCS;   Catholic University, Italy;   Southlake Regional Health Centre;   Stanford University;   University of Kansas;   The University of Texas Medical Branch, Galveston;   University of Foggia;   Sutter Health
Active, not recruiting - verified May 2015

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