Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Inflammatory Response as a Prognostic Factor of Recurrence of Atrial Fibrillation After Ablation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Medical University of Warsaw
Recruiting - verified July 2016

Factors Associated to the Instability of the INR (International Normalized Ratio ) in the Prevention of Thromboembolism AVK (Anti Vitamin K) in Atrial Fibrillation in the Elderly: Instead of Comorbidities

Condition:   Older Patient
Intervention:   Other: Charlson comorbidity index
Sponsor:   Nantes University Hospital
Completed - verified July 2016

Investigation of the Adagio PolarStar System in Patients With Paroxysmal Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Atrial Flutter
Intervention:   Device: PolarStar System
Sponsor:   Adagio Medical
Recruiting - verified July 2016

Sub-Clinical Atrial Fibrillation Biomarker Study

Condition:   Subclinical Atrial Fibrillation
Intervention:  
Sponsors:   Ottawa Heart Institute Research Corporation;   Population Health Research Institute;   Genome Canada
Not yet recruiting - verified July 2016

Ultrasound-guided Femoral Vein Accessibility, Safety and Time for Atrial Fibrillation Treatment

Conditions:   Atrial Fibrillation;   Peripheral Vascular Disease;   Vascular Access Complications
Interventions:   Device: Real-time ultrasound-guided puncture;   Other: Anatomical landmark guided puncture
Sponsor:   Kenichiro Yamagata
Recruiting - verified July 2016

Detection Rate of Atrial Fibrillation in Patients Implanted With ILRs

Condition:   Atrial Fibrillation
Intervention:   Other: No intervention
Sponsor:   Cambridge University Hospitals NHS Foundation Trust
Completed - verified July 2016

Review of the Safety and Effectiveness of the THERMOCOOL SMARTTOUCH® SF Catheter Evaluated for Treating Symptomatic PersistenT AF (PRECEPT)

Condition:   Atrial Fibrillation
Intervention:   Device: THERMOCOOL SMARTTOUCH® SF catheter
Sponsor:   Biosense Webster, Inc.
Recruiting - verified July 2016

TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis

Condition:   Aortic Valve Stenosis
Interventions:   Device: SAPIEN 3;   Procedure: SAVR
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2016

Age Related D-dimer Evaluation for the Exclusion of a Left Atrium Thrombus in Patients With Atrial Fibrillation (ADDIT-AF)

Condition:   Atrial Fibrillation
Intervention:   Procedure: Blood sampling
Sponsor:   Brugmann University Hospital
Not yet recruiting - verified July 2016

Treatment Convenience in Patients Treated With Dabigatran for Stroke Prophylaxis in Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension

Condition:   Hypertension Resistant to Conventional Therapy
Interventions:   Drug: Spironolactone;   Drug: Furosemide,;   Drug: Amiloride;   Drug: Ramipril;   Drug: Bisoprolol
Sponsor:   Sao Jose do Rio Preto University
Recruiting - verified July 2016

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsor:   Bayer
Recruiting - verified July 2016

Assessment of Reconstruction and Inverse Reconstruction in Right Atrium by Multimodal Echocardiographic Techniques

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: radiofrequency ablation (RFCA)
Sponsor:   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Recruiting - verified April 2016

Patient Convenience Study (RE-SONANCE)

Conditions:   Atrial Fibrillation;   Stroke
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Patient Convenience Study

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified July 2016

Subtherapeutic INR Levels in Patients With AVK: Incidence, Associated Factors, Prognosis and Control Strategies

Condition:   Atrial Fibrillation
Intervention:   Drug: Vitamin K Antagonist
Sponsors:   Bayer;   Janssen Research & Development, LLC
Active, not recruiting - verified July 2016

AF Patient Preference Study

Condition:   Atrial Fibrillation
Interventions:   Drug: VKA: Warfarin (Waran);   Drug: NOAC: Rivaroxaban (Xarelto, BAY59-7939);   Drug: NOAC: Dabigatran etexilate;   Drug: NOAC: Apixaban;   Drug: NOAC: Edoxaban;   Drug: NOAC: Lixiana
Sponsor:   Bayer
Recruiting - verified July 2016

Influence of Sleep Apnea on Risk of Atrial Fibrillation

Conditions:   Sleep Apnea;   Atrial Fibrillation
Intervention:   Other: Continuous Positive Airway Pressure
Sponsors:   The Cleveland Clinic;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2016

Anticoagulation Preference by AF Patients Study

Condition:   Atrial Fibrillation
Interventions:   Other: VKAs;   Other: NOACs including Rivaroxaban (Xarelto, BAY59-7939);   Other: Edoxaban;   Other: Apixaban;   Other: Dabigatran-etexilate
Sponsor:   Bayer
Recruiting - verified July 2016

Mobile Phones in Cryptogenic Stroke Patients Bringing Single Lead ECGs to Detect Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Ischemic Stroke;   Transient Ischemic Attack
Interventions:   Device: Single lead ECG device;   Device: 7-Day Holter monitor.
Sponsors:   Leiden University Medical Center;   Medical Center Haaglanden;   Groene Hart Ziekenhuis;   Herning Hospital;   Bronovo Hospital
Recruiting - verified July 2016

Real Evidence of Anticoagulation Treatment in Non-valvular Atrial Fibrillation in Germany, UK and France: REACT-AF2

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Bristol-Myers Squibb;   IMS Health;   Oxon Epidemiology
Active, not recruiting - verified July 2016

Adherence to New Oral Anticoagulation Therapy in Turkey

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Cardiovascular Academy Society, Turkey
Completed - verified July 2016

Comparison Between Thoracoscopic Left Atrial Appendage Excision and Warfarin for the Secondary Prevention of Stroke in Patients With AF

Conditions:   Atrial Fibrillation;   Stroke;   Systemic Embolism
Interventions:   Procedure: Thoracoscopic Left Atrial Appendage Excision;   Drug: Warfarin
Sponsor:   The First Affiliated Hospital with Nanjing Medical University
Recruiting - verified July 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified July 2016

Amplatzer™Amulet™ Post-Market Study

Conditions:   Atrial Fibrillation;   Thromboembolism;   Stroke
Intervention:   Device: Subjects implanted with Amulet Device
Sponsor:   St. Jude Medical
Recruiting - verified July 2016

MediGuide Registry

Conditions:   Heart Failure;   Cardiac Arrhythmia
Interventions:   Procedure: CRT implantation;   Device: MediGuide;   Procedure: EP
Sponsor:   St. Jude Medical
Enrolling by invitation - verified July 2016

SMART-SF Radiofrequency Ablation Safety Study

Condition:   Atrial Fibrillation
Intervention:   Device: THERMOCOOL® SMARTTOUCH® (RF ablation treatment)
Sponsor:   Biosense Webster, Inc.
Active, not recruiting - verified July 2016

Validation of Ambulatory Sleep Test (WP200/U) Compared In-lab Sleep Testing in Cardiac Subjects

Condition:   Sleep Disorders
Intervention:  
Sponsor:   Itamar-Medical, Israel
Completed - verified April 2016

ABLATOR Ablation Observational Registry

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   St. Jude Medical
Active, not recruiting - verified July 2016

CCC Project - Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Beijing Institute of Heart, Lung and Blood Vessel Diseases;   American Heart Association;   Chinese Society of Cardiology
Recruiting - verified July 2016

Berlin Atrial Fibrillation Registry

Conditions:   Acute Ischemic Stroke;   Atrial Fibrillation
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Center for Stroke Research Berlin;   Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma
Recruiting - verified July 2016

REPRISE Next Generation Delivery System

Condition:   Aortic Stenosis
Intervention:   Device: Lotus Valve and LOTUS Edge Valve System
Sponsor:   Boston Scientific Corporation
Recruiting - verified July 2016

Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department

Condition:   Atrial Fibrillation
Interventions:   Drug: Pharmacological cardioversion - Flecainide;   Procedure: Electrical cardioversion;   Drug: Metoprolol;   Drug: Verapamil;   Drug: Digoxin;   Drug: Pharmacological cardioversion - Amiodarone
Sponsors:   Maastricht University Medical Center;   ZonMw: The Netherlands Organisation for Health Research and Development
Recruiting - verified July 2016

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Atrial Fibrillation, Cardiac Symptoms, and Anxiety

Conditions:   Atrial Fibrillation;   Anxiety
Intervention:   Behavioral: Mindfulness and Interoceptive Exposure
Sponsor:   Brigham and Women's Hospital
Suspended - verified July 2016

Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation

Condition:   Postoperative Atrial Fibrillation
Interventions:   Drug: Amiodarone;   Procedure: DC-cardioversion;   Drug: Rate Control
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI);   National Institute of Neurological Disorders and Stroke (NINDS);   Canadian Institutes of Health Research (CIHR)
Completed - verified July 2016

Swiss Atrial Fibrillation Cohort Study

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation;   Medical Image Analysis Center (MIAC) Basel;   Schiller AG Baar;   Clinical Trial Unit, University Hospital Basel, Switzerland;   Cardiovascular Research Institute (CRIB) Basel;   Cardiocentro Ticino
Recruiting - verified July 2016

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Condition:   Atrial Fibrillation
Interventions:   Drug: Apixaban;   Drug: Parenteral heparin and/or oral Vitamin K antagonist
Sponsors:   Pfizer;   Bristol-Myers Squibb
Recruiting - verified July 2016

Rivaroxaban Versus Warfarin in Acute Ischemic Stroke With Atrial Fibrillation

Conditions:   Ischemic Stroke;   Transient Ischemic Attack
Interventions:   Drug: Rivaroxaban;   Drug: Warfarin
Sponsors:   Asan Medical Center;   Bayer
Completed - verified July 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified July 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified July 2016

A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurrence

Conditions:   Persistent Atrial Fibrillation;   Paroxysmal Atrial Fibrillation;   Hypertension;   Renal Denervation;   Cardiac Ablation
Interventions:   Device: Renal Artery Ablation Catheter;   Device: Cardiac Ablation
Sponsor:   St. Jude Medical
Recruiting - verified July 2016

Eliquis Regulatory Post Marketing Surveillance

Condition:   NonValvular Atrial Fibrillation
Intervention:   Drug: Apixaban
Sponsor:   Bristol-Myers Squibb
Recruiting - verified July 2016

Exploring the Efficacy of Once Daily Oral Rivaroxaban for Treatment of Thrombus in Left Atrial/Left Atrial Appendage in Subjects With Nonvalvular Atrial Fibrillation or Atrial Flutter

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Completed - verified December 2015

ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial

Condition:   End Stage Renal Failure on Dialysis
Interventions:   Drug: Spironolactone;   Drug: Placebo
Sponsors:   University Hospital, Brest;   Central Hospital, Nancy, France;   Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - verified July 2016

nMARQ™ Pulmonary Vein Isolation System for the Treatment of Paroxysmal Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Device: nMARQ Navigation Catheters;   Device: NaviStar ThermoCool Catheters
Sponsor:   Biosense Webster, Inc.
Active, not recruiting - verified July 2016

Canakinumab for the Prevention of Recurrences After Electrical Cardioversion: CONVERT-AF

Condition:   Atrial Fibrillation
Interventions:   Biological: Canakinumab;   Biological: Placebo
Sponsor:   University Hospital, Basel, Switzerland
Recruiting - verified July 2016

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Completed - verified July 2016

SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa (Dabigatran etexilate mesilate)
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Continued Access to PREVAIL (CAP2)

Condition:   Atrial Fibrillation
Intervention:   Device: WATCHMAN LAA Closure Technology
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified July 2016

ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal AF

Conditions:   Persistent Atrial Fibrillation;   Longstanding Persistent Atrial Fibrillation
Intervention:   Device: Synergy Ablation System
Sponsor:   AtriCure, Inc.
Active, not recruiting - verified July 2016

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Completed - verified May 2016

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2016

Early Percutaneous Mitral Intervention in Asymptomatic Moderate Mitral Stenosis

Condition:   Moderate Mitral Stenosis
Intervention:   Procedure: Percutaneous Mitral Commissurotomy
Sponsor:   Asan Medical Center
Active, not recruiting - verified July 2016

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Conditions:   Heart; Dysfunction Postoperative, Cardiac Surgery;   Genetic Predisposition to Disease;   Atrial Fibrillation;   Myocardial Infarction;   Heart Failure
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   Texas Heart Institute;   University of Texas Southwestern Medical Center
Recruiting - verified July 2016

Use of the Hansen Medical System in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: Ablation
Sponsor:   Hansen Medical
Active, not recruiting - verified July 2016

Intravenous Lidocaine and Postoperative Outcomes After Cardiac Surgery

Condition:   Atrial Fibrillation
Interventions:   Drug: Lidocaine;   Other: Placebo
Sponsor:   The Cleveland Clinic
Recruiting - verified July 2016

Gene Expression Profiling in Subjects With Postoperative Atrial Fibrillation After Cardiac Surgery

Condition:   Atrial Fibrillation
Intervention:   Other: Atrial biopsy
Sponsor:   Brigham and Women's Hospital
Recruiting - verified July 2016

Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery

Condition:   Cardiac Surgery
Interventions:   Other: Hyperinsulinemic-normoglycemic clamp;   Other: insulin at the standard of care levels
Sponsor:   The Cleveland Clinic
Recruiting - verified July 2016

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