Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

CardioFocus vs. Contact Force Guided Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Device: Ablation catheter
Sponsor:   I-Med-Pro GmbH
Not yet recruiting - verified February 2017

Effect of Antithrombotic Theatment in Patients With Coronary Heart Disease Complicated With Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Coronary Heart Disease
Intervention:  
Sponsor:   Henan Institute of Cardiovascular Epidemiology
Recruiting - verified February 2017

Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL)

Conditions:   Atrial Fibrillation Chronic;   Persistent Atrial Fibrillation
Interventions:   Procedure: Cryo or RF Ablation only of Pulmonary Veins;   Drug: Cryo or RF Ablation of Pulmonary Veins plus Ablation of the PLAW
Sponsor:   Arash Aryana, MD
Recruiting - verified February 2017

Mediterranean Diet Plus Extravirgin Olive Oil in the Prevention of Recurrent Arrhythmias. The PREDIMAR (PREvención Con DIeta Mediterránea de Arritmias Recurrentes) Trial

Conditions:   Atrial Fibrillation;   Atrial Arrhythmia
Intervention:   Dietary Supplement: Mediterranean diet plus extra virgin olive oil
Sponsors:   Fundación de investigación HM;   University of Navarra;   University Hospital Virgen de las Nieves
Not yet recruiting - verified February 2017

Study Comparing Pulmonary Vein Isolation With the Cryoballoon and Radiofrequency Energy(Contact Force) in the Treatment of Persistent Atrial Fibrillation (AF) (Cryo Vs CF in PerAF)

Condition:   Persistent Atrial Fibrillation
Interventions:   Device: Cryoballoon;   Device: Radiofrequency Energy(Contact Force)
Sponsor:   China Cardiometabolic Registries
Recruiting - verified February 2017

Assessment of Myocardial Ischemic-Reperfusion Injury During Off- and On- Pump CABG

Conditions:   Ischemic Heart Disease;   Coronary Artery Disease;   Ischemic Reperfusion Injury;   CABG
Interventions:   Procedure: On-Pump CABG.;   Procedure: Off-Pump CABG.;   Procedure: BH-CABG MSC.
Sponsor:   St. Petersburg State Pavlov Medical University
Recruiting - verified February 2017

STOP Persistent AF

Condition:   Atrial Fibrillation
Intervention:   Device: Arctic Front Advance Cardiac CryoAblation Catheter
Sponsor:   Medtronic Atrial Fibrillation Solutions
Not yet recruiting - verified February 2017

MultiCenter expeRience in AFib Patients Treated With OAC (CRAFT)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Medical University of Warsaw
Recruiting - verified February 2017

Evaluation of a Multi-electrode Linear Type Catheter (D-1368-01-SI)

Condition:   Persistent Atrial Fibrillation
Intervention:   Device: Endocardial Ablation Procedure
Sponsor:   Biosense Webster, Inc.
Recruiting - verified February 2017

Automated Physician Notifications to Improve Guideline-Based Anticoagulation in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Other: Baseline alert
Sponsors:   Massachusetts General Hospital;   Boehringer Ingelheim
Active, not recruiting - verified February 2017

Benchmarking an Oral Anticoagulant Treatment Rate in Patients With Nonvalvular Atrial Fibrillation

Condition:   Nonvalvular Atrial Fibrillation
Intervention:  
Sponsors:   Baim Institute for Clinical Research;   American College of Cardiology
Enrolling by invitation - verified September 2016

AMPLATZER™ Amulet™ LAA Occluder Trial

Condition:   Stroke
Interventions:   Device: Amulet Left Atrial Appendage Occluder;   Device: WATCHMAN Left Atrial Appendage Closure
Sponsor:   St. Jude Medical
Recruiting - verified February 2017

Verification of XAPPORT: a Decision Support App for Physicians Used for Patients Anticoagulated With Rivaroxaban in Terms of Anticoagulation Management in Elective Surgery: Verification Process of Medical Decision Algorithm

Conditions:   Atrial Fibrillation;   Venous Thromboembolism;   Pulmonary Embolism
Interventions:   Other: XAPPORT;   Other: Expert Panel ("gold standard")
Sponsors:   Bayer;   Janssen Research & Development, LLC
Not yet recruiting - verified February 2017

Preliminary Testing of the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station

Conditions:   Urinary Tract Infection;   Diabetes Mellitus;   Atrial Fibrillation;   OSA;   COPD;   Pneumonia;   Acute Otitis Media;   Leukocytosis;   Iron Deficient Anemia;   Hypertension;   Healthy Volunteers
Intervention:   Device: Vitaliti
Sponsor:   Cloud DX Inc.
Enrolling by invitation - verified February 2017

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

Transcutaneous Autonomic Modulation in Thoracic Surgery

Conditions:   Atrial Fibrillation, Postoperative;   Postoperative Complications;   Inflammation
Interventions:   Device: Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS);   Device: Sham LLVNS
Sponsor:   Duke University
Recruiting - verified April 2016

The IPED (Investigation of Palpitations in the ED) Study

Conditions:   Presyncope;   Arrhythmias, Cardiac;   Tachycardia, Supraventricular;   Atrial Fibrillation
Intervention:   Device: AliveCor Heart Monitor
Sponsor:   NHS Lothian
Recruiting - verified January 2017

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage

Condition:   Aortic Valve Disorder
Interventions:   Device: Lotus Heart valve system;   Device: WATCHMAN
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified February 2017

Watchman FLX Left Atrial Appendage Closure Device Post Approval Study

Condition:   Non-valvular Atrial Fibrillation
Intervention:   Device: Watchman FLX
Sponsor:   Boston Scientific Corporation
Not yet recruiting - verified February 2017

Predictors for Postoperative Delirium After Cardiac Surgery in Adults: a One-year, Single Center, Observational Cohort Study

Condition:   Postoperative Delirium
Intervention:   Other: no intervention
Sponsor:   University Hospital, Basel, Switzerland
Completed - verified February 2017

Feasibility Study of a Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Device: Aegis Sentinel Ligation System
Sponsors:   Aegis Medical Innovations;   Applied Health Research Centre
Not yet recruiting - verified February 2017

Risk Factors for Delirium Following Cardiac Surgery

Condition:   Delirium
Interventions:   Drug: Statin, beta blocker;   Other: Cardiopulmonary bypass
Sponsor:   Vanderbilt University
Completed - verified February 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

An Observational Cross-sectional Study Evaluating the Sociodemographic and Clinical Characteristics of Patients Diagnosed With NVAF With a Risk of Stroke or Systemic Embolism, Who Are on Treatment to Adequately Control Their Coagulation and Treated in Primary Care Centres

Conditions:   Stroke;   Prevention and Control;   Atrial Fibrillation
Intervention:   Drug: Direct Oral Anticoagulant (DOAC)
Sponsor:   Bayer
Completed - verified February 2017

Hybrid Versus Catheter Ablation in Persistent AF

Condition:   Atrial Fibrillation
Interventions:   Procedure: Hybrid Ablation;   Procedure: Catheter Ablation
Sponsor:   Maastricht University Medical Center
Recruiting - verified February 2017

Profile and Antithrombotic Management of Patients With NVAF Attending Internal Medicine Departments in Spain (PERFILAR Study)

Condition:   Anticoagulation, Blood Thinners , Atrial Fibrillation, Bleeding, Stroke
Intervention:  
Sponsor:   Bristol-Myers Squibb
Completed - verified February 2017

Ablation Verses Anti-arrhythmic Therapy for Reducing All Hospital Episodes From Recurrent Atrial Fibrillation

Conditions:   Heart Failure;   Recurrent Atrial Fibrillation
Interventions:   Procedure: AVATAR-AF ablation;   Drug: Anti-Arrhythmic therapy;   Procedure: Conventional AF ablation
Sponsor:   Imperial College London
Recruiting - verified August 2016

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2016

Postmarket Evaluation of the Phased Radio Frequency Ablation System (GOLD AF Registry)

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Medtronic Atrial Fibrillation Solutions;   IHF GmbH - Institut für Herzinfarktforschung
Recruiting - verified February 2017

Home-Based Screening for Early Detection of Atrial Fibrillation in Primary Care Patients Aged 75 Years and Older

Conditions:   Atrial Fibrillation;   Hypertension
Intervention:   Device: Screening: Intervention - Atrial fibrillation screening (ZIO XT ECG monitor, Watch-BP)
Sponsors:   Population Health Research Institute;   Canadian Stroke Prevention Intervention Network;   Canadian Institutes of Health Research (CIHR);   Heart and Stroke Foundation of Canada;   Canadian Stroke Network;   Boehringer Ingelheim;   iRhythm Technologies, Inc.;   Microlife
Recruiting - verified February 2017

Canadian Community Utilization of Stroke Prevention Study - Emergency Department

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Other: Retrospective review of OAC prescription;   Other: Prescription of OAC in ED;   Other: Community AF clinic
Sponsor:   Population Health Research Institute
Active, not recruiting - verified February 2017

Validation of Rivaroxaban Assay for US Registration

Condition:   Patients Receiving Rivaroxaban Treatment
Intervention:   Device: STA- Rivaroxaban Calibrator&Control
Sponsor:   Diagnostica Stago
Completed - verified February 2017

Multimodal Image Processing Software to Guide Cardiac Ablation Therapy

Conditions:   Ventricular Arrhythmias;   Persistent Atrial Fibrillation
Interventions:   Device: Contrast-enhanced ECG-gated multi-detector computed tomography;   Device: Magnetic resonance imaging;   Device: Positron emission tomography;   Device: Body surface mapping;   Procedure: Cardiac ablation procedure
Sponsor:   University Hospital, Bordeaux
Completed - verified February 2017

Program for the Identification of "Actionable" Atrial Fibrillation in the Family Practice Setting

Condition:   Atrial Fibrillation
Interventions:   Other: 30 Second Pulse Check;   Device: Watch BP Home A;   Device: HeartCheck Hand-held ECG device
Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research (CIHR)
Completed - verified February 2017

Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers

Condition:   Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Sotalol;   Drug: Placebo for BMS-919373
Sponsor:   Bristol-Myers Squibb
Terminated - verified February 2017

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Drug: BMS-919373;   Drug: Placebo (Matching with BMS-919373)
Sponsor:   Bristol-Myers Squibb
Completed - verified June 2016

Vasoactive Drugs in Intensive Care Unit

Condition:   Shock
Interventions:   Drug: Norepinephrine;   Drug: Epinephrine;   Drug: Phenylephrine;   Drug: Vasopressin
Sponsor:   University of Chicago
Recruiting - verified February 2017

Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Hypertension
Interventions:   Drug: Renal nerve denervation;   Device: Cryoablation
Sponsor:   Medtronic Atrial Fibrillation Solutions
Recruiting - verified February 2017

Atrial Fibrillation Detected by Continuous ECG Monitoring

Conditions:   Atrial Fibrillation;   Stroke;   Hypertension;   Diabetes
Intervention:   Device: LOOP recorder (Medtronic LINQ device)
Sponsors:   Rigshospitalet, Denmark;   Bispebjerg Hospital;   Zealand University Hospital;   Odense University Hospital;   University of Southern Denmark;   Aalborg University
Active, not recruiting - verified February 2017

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

Condition:   Persistent Atrial Fibrillation
Interventions:   Device: Convergent Procedure EPi-Sense-AF Guided Coagulation System;   Device: Endocardial Catheter Ablation
Sponsor:   AtriCure, Inc.
Recruiting - verified February 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified February 2017

Atrial Pressure Electrophysiology Pilot Study

Condition:   Atrial Fibrillation
Interventions:   Device: ThermoCool® SF NAV Catheter;   Device: ThermoCool® catheter
Sponsors:   Scott Martin Miller, MD;   Biosense Webster, Inc.
Terminated - verified February 2017

Canakinumab for the Prevention of Recurrences After Electrical Cardioversion: CONVERT-AF

Condition:   Atrial Fibrillation
Interventions:   Biological: Canakinumab;   Biological: Placebo
Sponsor:   University Hospital, Basel, Switzerland
Terminated - verified February 2017

REVEAL AF: Incidence of AF in High Risk Patients

Condition:   Atrial Fibrillation
Intervention:   Device: REVEAL Implantable cardiac monitor
Sponsor:   Medtronic Cardiac Rhythm and Heart Failure
Active, not recruiting - verified February 2017

Post-Marketing Surveillance of Prazaxa® on the Long-term Use in Patients With Nonvalvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Prazaxa
Sponsor:   Boehringer Ingelheim
Completed - verified February 2017

First Arrhythmia Collection of Transvenous and Simultaneous Subcutaneous Implantable Defibrillator Data

Conditions:   Ventricular Tachycardia;   Ventricular Fibrillation;   Atrial Fibrillation
Intervention:  
Sponsor:   Boston Scientific Corporation
Completed - verified February 2017

Timing of Direct Current Cardioversion (DCC) in Patients Undergoing Ablation of Persistent/Permanent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: DCC first then PVI;   Procedure: PVI then DCC after
Sponsor:   The Cleveland Clinic
Completed - verified January 2017

Implantable Loop Recorders in Post-atrial Fibrillation (AF) Ablation: RPAF-A

Condition:   Atrial Fibrillation
Intervention:   Other: TTM and Holter monitor
Sponsor:   The Cleveland Clinic
Completed - verified February 2017

Selective AV Nodal Vagal Stimulation For Reduction of the Ventricular Rate During Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   The Cleveland Clinic
Withdrawn - verified February 2017

PAF-HEFT (Permanent Atrial Fibrillation in Heart Failure Trial)

Conditions:   Atrial Fibrillation;   Heart Failure
Interventions:   Procedure: Ablation;   Other: Rate Control
Sponsors:   Medtronic Bakken Research Center;   Medtronic
Terminated - verified February 2017

CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atrial Fibrillation

Conditions:   Heart Failure;   Sudden Cardiac Death;   Atrial Fibrillation
Interventions:   Device: Conducted AF-Response Algorithm (CAFR) On;   Device: Conducted AF-Response Algorithm (CAFR) Off
Sponsors:   Medtronic Bakken Research Center;   Medtronic
Terminated - verified January 2017

Clinical and Economic Consequences of Left Atrial Bipolar Radiofrequency Ablation of Persistent and Permanent Atrial Fibrillation During Cardiac Surgery

Conditions:   Atrial Fibrillation;   Coronary Artery Disease
Intervention:   Procedure: bipolar radiofrequency ablation of persistent and permanent AF
Sponsors:   Medtronic Bakken Research Center;   Medtronic
Terminated - verified February 2017

EnTRINSIC - EnPulse Trial on Search AV+ Influence

Condition:   Arrhythmia, Sinus
Intervention:   Device: Search AV+ algorithm
Sponsors:   Medtronic Bakken Research Center;   Medtronic
Terminated - verified February 2017

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