Atrial Fibrillation Also called: AF, AFib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Comparative Effectiveness and Safety Between Warfarin and Dabigatran

Condition:   Atrial Fibrillation
Interventions:   Drug: Warfarin;   Drug: Dabigatran
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified August 2017

Medical Need of OAC Reversal

Condition:   Atrial Fibrillation
Interventions:   Drug: warfarin;   Drug: dabigatran;   Drug: Apixaban;   Drug: Edoxaban;   Drug: Rivaroxaban
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified August 2017

Renal Nerve Denervation After Pulmonary Vein Isolation for Persistent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Renal Nerve Denervation;   Procedure: Pulmonary vein isolation
Sponsor:   Chinese University of Hong Kong
Not yet recruiting - verified August 2017

Edoxaban Treatment in Routine Clinical Practice for Patients With Non-Valvular Atrial Fibrillation (NVAF)

Condition:   Atrial Fibrillation
Intervention:   Drug: Edoxaban
Sponsor:   Daiichi Sankyo (Thailand) Ltd., a Daiichi Sankyo Company
Not yet recruiting - verified August 2017

Edoxaban Treatment in Routine Clinical Practice for Patients With Non-valvular Atrial Fibrillation (ETNA-AF-Hong Kong)

Condition:   Atrial Fibrillation
Intervention:   Drug: Edoxaban
Sponsor:   Daiichi Sankyo Hong Kong Ltd., a Daiichi Sankyo Company
Recruiting - verified August 2017

Oesophageal Probe Evaluation in RF Ablation of Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Device: Placement of oesophageal probe for temperature measurement;   Device: Power limitation of RF generator
Sponsor:   Heartcenter Leipzig GmbH
Recruiting - verified August 2017

Effects of PAP on Afib Recurrence Risk After Catheter Ablation in OSA Patients

Conditions:   Obstructive Sleep Apnea;   Atrial Fibrillation
Intervention:   Procedure: Cardiac Ablation for Atrial Fibrillation
Sponsor:   Stanford University
Not yet recruiting - verified August 2017

A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)

Condition:   Heart Failure With Preserved Ejection Fraction
Interventions:   Drug: IW-1973;   Drug: Placebo Oral Tablet
Sponsor:   Ironwood Pharmaceuticals, Inc.
Not yet recruiting - verified June 2017

AF Septal Pacing (Clinical Investigation Plan)

Condition:   Persistent and Paroxysmal Atrial Fibrillation
Intervention:   Procedure: Pulmonary vein ablation
Sponsor:   Medtronic BRC
Not yet recruiting - verified August 2017

The Impact of Obesity on Postoperative Outcomes Following Cardiac Surgery

Conditions:   Obesity;   Cardiac Disease;   Cardiovascular Syndromes, Metabolic
Intervention:   Procedure: cardiac surgery
Sponsors:   Cardiovascular Research New Brunswick;   Horizon Health Network;   Maritime Heart Centre
Recruiting - verified August 2017

ARBITRAGE : cARdiotoxicity Profile of aBIraTeRone in prostAte Cancer : a pharmacoviGilancE Study

Conditions:   Arrhythmias, Cardiac;   Atrial Fibrillation and Flutter;   Tachycardia, Supraventricular;   Cardiac Failure
Intervention:   Drug: L02 (sex hormones used in treatment of neoplastic diseases) and G03 (sex hormones)
Sponsor:   Groupe Hospitalier Pitie-Salpetriere
Completed - verified July 2017

The Effect of Nitroglycerin Infusion Rate on Cerebral Rewarming During Hypothermic Coronary Artery Bypass Grafting

Conditions:   Coronary Artery Bypass;   Cardiopulmonary Bypass
Interventions:   Drug: Glyceryl trinitrate 0.2;   Drug: Glyceryl trinitrate 0.5
Sponsor:   Rize Üniversitesi
Not yet recruiting - verified August 2017

Patients' Assessment of Satisfaction for Stroke Prevention in Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa®
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

The Efficacy of Single Coil Defibrillation Leads for Internal Cardioversion of Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Internal Cardioversion;   Procedure: External Cardioversion
Sponsor:   University of Kentucky
Recruiting - verified August 2017

Bleeding Risk Evaluation in Haemophilia Patients Under Antiplatelet Therapies

Condition:   Hemophilia
Intervention:   Other: Non interventional study
Sponsor:   Nantes University Hospital
Recruiting - verified August 2017

Health-related Quality of Life in Patients on Anticoagulants

Condition:   Atrial Fibrillation
Interventions:   Drug: DOAC or VKA;   Drug: VKA
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Left Atrial Function in Recurrent Stroke of Unknown Cause

Condition:   Stroke
Intervention:  
Sponsors:   Hasselt University;   Jessa Hospital
Completed - verified August 2017

Edoxaban Treatment in Routine Clinical Practice for Patients With Atrial Fibrillation in Korea and Taiwan (ETNA-AF-KOR-TWN)

Condition:   Atrial Fibrillation
Intervention:   Drug: Edoxaban
Sponsors:   Daiichi Sankyo, Inc.;   Quintiles, Inc.;   A+ Inc.
Recruiting - verified August 2017

The European Registry of Older Subjects With Atrial Fibrillation (EUROSAF)

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Alberto Pilotto;   Bayer
Recruiting - verified August 2017

A Digital Non-interventional Atrial Fibrillation (AF) Screening Study With Commercial Pulse Detection Systems

Condition:   Atrial Fibrillation
Interventions:   Device: 12-point-ECG;   Device: Polar V800;   Device: 360° eMotion FAROS SET + Belt;   Device: Adidas Micoach smart run;   Device: TomTom Runner Cardio HRM
Sponsor:   Bayer
Not yet recruiting - verified August 2017

Benefit-Risk Of Arterial THrombotic prEvention With Rivaroxaban for Atrial Fibrillation in France

Condition:   Atrial Fibrillation
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Vitamin K antagonists;   Drug: dabigatran (Pradaxa)
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified August 2017

DURABLE-I Study: Dielectric Unravelling of Radiofrequency ABLation Effectiveness

Condition:   Atrial Fibrillation
Intervention:   Device: D700 System
Sponsor:   EP Dynamics Research Ltd
Recruiting - verified September 2016

Xarelto Evidence in Real Life of Patients' Preference and Satisfaction Study

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified August 2017

Treatment Convenience in Patients Treated With Dabigatran for Stroke Prophylaxis in Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Patient Convenience Study- NIS RELATE

Condition:   Atrial Fibrillation
Interventions:   Drug: Pradaxa (dabigatran);   Drug: Vitamin K antagonist
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study

Condition:   Stroke
Intervention:   Drug: Rivaroxaban (Xarelto, BAY 59-7939)
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified August 2017

Clinical Impact of Autonomic Modulation After Pulmonary Vein Isolation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Klinik für Kardiologie, Pneumologie und Angiologie
Completed - verified August 2017

Isolation of Pulmonary Veins With the Aid of Magnetic Resonance Imaging

Condition:   Atrial Fibrillation
Interventions:   Procedure: Conventional AF ablation;   Procedure: LGE-MRI guided AF ablation
Sponsors:   Hospital Clinic of Barcelona;   Institut d'Investigacions Biomèdiques August Pi i Sunyer;   University of Barcelona
Recruiting - verified August 2017

Feasibility Study of a Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Device: Aegis Sierra Ligation System
Sponsors:   Aegis Medical Innovations;   Applied Health Research Centre
Recruiting - verified August 2017

Laser Ablation Study for trEatment of atRial Fibrillation (LASER)

Condition:   Atrial Fibrillation
Interventions:   Device: Laser ablation;   Device: RF ablation
Sponsors:   Hospital Clinic of Barcelona;   CardioFocus
Recruiting - verified August 2017

Supervised Exercise Compared to PAP in Patients With Permanent Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Other: Exercise;   Other: Physical activity
Sponsor:   Göteborg University
Recruiting - verified August 2017

Physiotherapist Led Group-exercise Compared Physical Activity on Prescription, a 3 Months Follow-up

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Göteborg University
Recruiting - verified August 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified August 2017

Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department

Condition:   Atrial Fibrillation
Interventions:   Drug: Pharmacological cardioversion - Flecainide;   Procedure: Electrical cardioversion;   Drug: Metoprolol;   Drug: Verapamil;   Drug: Digoxin;   Drug: Pharmacological cardioversion - Amiodarone
Sponsors:   Maastricht University Medical Center;   ZonMw: The Netherlands Organisation for Health Research and Development
Recruiting - verified August 2017

Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)

Condition:   Atrial Fibrillation
Interventions:   Drug: Dabigatran etexilate;   Drug: Phenprocoumon
Sponsor:   Boehringer Ingelheim
Active, not recruiting - verified August 2017

Efficacy, Safety and Efficiency of the nMARQ Pulmonary Vein Isolation System in Paroxysmal Atrial Fibrillation

Condition:   Paroxysmal Atrial Fibrillation
Intervention:   Procedure: ablation
Sponsors:   Basildon and Thurrock University Hospitals NHS Foundation Trust;   Anglia Ruskin University
Active, not recruiting - verified August 2017

Compare the Efficacy of Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft Surgery

Conditions:   Coronary Artery Bypass;   Antiplatelet Agents
Interventions:   Drug: Aspirin;   Drug: Ticagrelor
Sponsor:   Ruijin Hospital
Completed - verified August 2017

CABG REVEAL: Atrial Fibrillation After Coronary Artery Bypass Graft

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Saint Thomas Health
Active, not recruiting - verified July 2017

Cardiac Surgery and the Risk of Atrial Fibrillation: an Intervention Trial Evaluating Melatonin

Condition:   Atrial Fibrillation
Interventions:   Drug: Melatonin;   Drug: Placebo (for Melatonin)
Sponsor:   Johns Hopkins University
Recruiting - verified August 2017

Sequential Expansion of Comparative Effectiveness of Anticoagulants

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Randomized Trial Comparing Diltiazem and Metoprolol For Atrial Fibrillation Rate Control

Conditions:   Atrial Fibrillation;   Atrial Flutter
Interventions:   Drug: Metoprolol;   Drug: Diltiazem
Sponsor:   CAMC Health System
Recruiting - verified August 2017

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

Conditions:   Ischemic Stroke;   Atrial Fibrillation;   Transient Ischemic Attacks;   Transient Cerebrovascular Events;   Thrombotic Stroke;   Stroke of Basilar Artery;   Cardioembolic Stroke
Intervention:   Other: Biomarker blood draw
Sponsor:   Ischemia Care LLC
Recruiting - verified August 2017

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation

Conditions:   Heart Disease;   Congestive Heart Failure;   Atrial Fibrillation
Interventions:   Device: Optimal Medical therapy plus ICD;   Device: Optimal Medical therapy plus CRT/ICD
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research (CIHR)
Recruiting - verified August 2017

Optimizing Antithrombotic Care in Patients With AtriaL fibrillatiON and Coronary stEnt (OAC-ALONE) Study

Conditions:   Atrial Fibrillation;   Coronary Artery Disease
Intervention:   Drug: OAC alone
Sponsors:   Satoshi Shizuta;   Research Institute for Production Development;   Daiichi Sankyo Co., Ltd.
Active, not recruiting - verified August 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified August 2017

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsors:   Bayer;   Janssen Scientific Affairs, LLC
Recruiting - verified August 2017

Eliquis Regulatory Post Marketing Surveillance

Condition:   NonValvular Atrial Fibrillation
Intervention:   Drug: Apixaban
Sponsor:   Bristol-Myers Squibb
Active, not recruiting - verified August 2017

Anticoagulant Utilization Pattern

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Improved Prevention of Stroke in Primary Care in Stockholm, Sweden (Förbättrad Prevention av Stroke)

Conditions:   Ischemic Stroke;   Hemorrhagic Stroke;   TIA;   Atrial Fibrillation
Intervention:   Behavioral: structured collegial feed back
Sponsor:   Karolinska Institutet
Enrolling by invitation - verified August 2017

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2017

Atrioventricular Node Ablation in Patients With Atrial Fibrillation and Moderate Chronic Heart Failure

Condition:   Heart Failure
Interventions:   Device: Implantation of CRT device;   Device: Implantation of conventional VVI(R) pacemaker
Sponsor:   Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Recruiting - verified January 2017

Kansai Plus Atrial Fibrillation Trial

Condition:   Atrial Fibrillation
Interventions:   Procedure: ATP guide additional ablation.;   Drug: Antiarrhythmic drug (AAD);   Procedure: ATP guide additional ablation.;   Drug: Control;   Procedure: Control;   Drug: Antiarrhythmic drug (AAD);   Procedure: Control;   Drug: Control
Sponsor:   Kyoto University, Graduate School of Medicine
Completed - verified August 2017

Intravenous Lidocaine and Postoperative Outcomes After Cardiac Surgery

Condition:   Atrial Fibrillation
Interventions:   Drug: Lidocaine;   Other: Placebo
Sponsor:   The Cleveland Clinic
Recruiting - verified August 2017

Atrial Fibrillation Management in Congestive Heart Failure With Ablation

Conditions:   Persistent Atrial Fibrillation;   Heart Failure;   ICD
Interventions:   Device: ICD/CRT implant;   Procedure: AF ablation;   Other: Best Medical Treatment
Sponsor:   St. Jude Medical
Completed - verified August 2017

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