Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Extracellular RNAs in Relation to Cardiometabolic Risk

Conditions:   Subclinical Atherosclerotic Cardiovascular Disease;   Blood Pressure;   Obesity
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified July 17, 2017

Influence of Circulating Endothelial Progenitor Cells and Modifiable Vascular Risk Factors on Carotid Plaque Vulnerability

Conditions:   Atherosclerosis;   Stroke;   Inflammation
Sponsors:   Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau;   Instituto de Salud Carlos III
Recruiting - verified July 2017

Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)

Conditions:   Cardiovascular Diseases;   Diabetes;   Metabolic Syndrome;   Cancer;   Inflammatory Disease;   Atherosclerosis;   Cognitive Decline;   Liver Diseases;   Death;   Pain, Chronic;   Depression;   Infection;   Chronic Disease
Sponsor:   University of Eastern Finland
Active, not recruiting - verified July 2017

Gum Arabic as Antioxidant and Anti-inflammatory in Hemodialysis Patients

Condition:   End-Stage Renal Disease
Intervention:   Dietary Supplement: Gum Arabic
Sponsors:   Lamis Kaddam;   Military Hospital Sudan;   University of Khartoum
Enrolling by invitation - verified July 2017

PET-MRI Imaging in Patients With Acute Neurovascular Syndrome

Conditions:   Stroke;   Carotid Stenosis
Interventions:   Radiation: 18F PET-MRI;   Diagnostic Test: Transcranial Doppler
Sponsor:   University of Edinburgh
Not yet recruiting - verified July 2017

PET-MRI Imaging in Patients With Symptomatic Carotid Artery Stenosis

Conditions:   Stroke;   Carotid Stenosis
Interventions:   Procedure: CEA;   Radiation: 18F PET-MRI;   Diagnostic Test: Transcranial Doppler
Sponsor:   University of Edinburgh
Not yet recruiting - verified July 2017

Autologous BMMNC Combined With HA Therapy for PAOD

Conditions:   Peripheral Arterial Occlusive Disease;   Critical Limb Ischemia
Intervention:   Biological: RV-P1501
Sponsors:   Academia Sinica, Taiwan;   National Taiwan University Hospital;   National Cheng-Kung University Hospital
Recruiting - verified July 2017

Real World Registry Assessing the Clinical Use of the Bard UltraScore Forced Focus PTA Balloon

Conditions:   Peripheral Arterial Disease;   Peripheral Vascular Diseases;   Arterial Occlusive Diseases
Intervention:   Device: PTA (UltraScore Focused Force PTA Balloon)
Sponsor:   C. R. Bard
Not yet recruiting - verified July 2017

Prognostic Value of Plasma DPP4 Activity in ST-elevation Myocardial Infarction Patients

Conditions:   Coronary Angiography;   Dipeptidyl Peptidase 4
Intervention:   Diagnostic Test: plasma DPP4 activity
Sponsor:   Chinese PLA General Hospital
Completed - verified July 2017

RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty

Conditions:   Peripheral Artery Disease;   Atherosclerosis;   Artery Diseases, Peripheral;   Plaque, Atherosclerotic;   Occlusive Arterial Disease
Interventions:   Device: RANGER™ Paclitaxel Coated Balloon;   Drug: Paclitaxel;   Procedure: Standard Balloon Angiplasty
Sponsor:   Boston Scientific Corporation
Recruiting - verified July 2017

IN.PACT BTK Randomized Study to Assess Safety and Efficacy of IN.PACT 014 vs. PTA

Conditions:   Critical Limb Ischemia;   Peripheral Arterial Disease
Interventions:   Device: DCB;   Device: PTA
Sponsor:   Medtronic Endovascular
Recruiting - verified July 2017

Tack Optimized Balloon Angioplasty Study of the Tack Endovascular System® in Below the Knee Arteries

Condition:   Peripheral Arterial Disease
Intervention:   Device: Tack Endovascular System
Sponsor:   Intact Vascular
Recruiting - verified July 2017

"All Comers" Post Market Clinical Follow-up (PMCF) With Multi-LOC for flOw liMiting Outcomes (LOCOMOTIVE Extended)

Condition:   Peripheral Arterial Occlusive Disease
Intervention:   Device: VascuFlex Multi-LOC®
Sponsors:   B. Braun Melsungen AG;   Diakonissenkrankenhaus Mannheim
Recruiting - verified July 2017

OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO

Conditions:   Accidental Falls;   Fall Due to Loss of Equilibrium;   High Risk of Falls Due to Mobility Limitation;   Diabetes;   Arthritis;   Cancer;   Peripheral Arterial Disease;   Parkinson's Disease;   End Stage Renal Failure on Dialysis
Interventions:   Device: AFO;   Other: Control
Sponsors:   Bijan Najafi;   Orthotic Holdings, Inc.
Recruiting - verified July 2017

Safety and Effectiveness of Jetstream Atherectomy System (J-SUPREME)

Condition:   Peripheral Arterial Disease
Intervention:   Device: Jetstream Atherectomy System
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified July 2017

99mTc-rhAnnexin V-128 Imaging for Carotid Atherosclerosis

Condition:   Carotid Artery Plaque
Intervention:   Radiation: 99mTc-rhAnnexin V-128
Sponsor:   Advanced Accelerator Applications
Recruiting - verified July 2017

Beauty From Within Community Screening Project

Condition:   Heart Health Screening and Prevention
Interventions:   Procedure: Fingerstick cholesterol test;   Other: Atherosclerosis Cardiovascular Disease Risk assessment;   Procedure: Blood pressure measurement
Sponsor:   Cedars-Sinai Medical Center
Active, not recruiting - verified July 2017

Safety and Efficacy Study of VM202 in the Treatment of Chronic Non-Healing Foot Ulcers

Condition:   Foot Ulcer, Diabetic
Interventions:   Genetic: VM202;   Other: Placebo
Sponsor:   ViroMed Co., Ltd. dba VM BioPharma
Recruiting - verified July 2017

Comprehensive Magnetic Resonance in Peripheral Arterial Disease.3

Condition:   Peripheral Arterial Disease
Intervention:   Other: Exercise
Sponsor:   University of Virginia
Recruiting - verified July 2017

Novel Treatment of Intermittent Claudication in Patients With Peripheral Arterial Disease Using Danshen Gegen (D&G) Capsule

Conditions:   Peripheral Arterial Disease;   Intermittent Claudication
Interventions:   Drug: Danshen Gegen Capsule;   Drug: Placebo
Sponsor:   Chinese University of Hong Kong
Recruiting - verified July 2017

Colchicine in Vascular Inflammation Assessed With PET Imaging

Condition:   Atherosclerotic Vascular Disease
Interventions:   Drug: Colchicine;   Drug: Placebo
Sponsor:   Montreal Heart Institute
Completed - verified July 2017

Pilot Safety Study of Injectable SIS for Critical Limb Ischemia

Conditions:   Critical Limb Ischemia;   Peripheral Arterial Disease;   Peripheral Vascular Disease
Intervention:   Device: Injectable SIS
Sponsor:   Cook Group Incorporated
Active, not recruiting - verified July 2017

Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women

Conditions:   Menopause;   Aging
Interventions:   Drug: KUVAN;   Drug: Placebo;   Drug: Cetrotide;   Drug: Climara;   Drug: Placebo transdermal patch
Sponsors:   University of Colorado, Denver;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified July 2017

A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb Ischemia

Conditions:   Critical Limb Ischemia;   Vascular Diseases;   Peripheral Arterial Disease
Intervention:   Biological: HGF Plasmid
Sponsor:   AnGes
Active, not recruiting - verified April 2017

Global Study of a Drug-coated Balloon to Treat Obstructive SFA and/or Popliteal Lesions

Condition:   Peripheral Arterial Disease
Intervention:   Device: CVI Paclitaxel-Coated PTA Balloon Catheter
Sponsor:   Spectranetics Corporation
Recruiting - verified July 2017

Study to Determine the Effect of Repeated Administration of Diltiazem on the Pharmacokinetics of Darapladib (Sb-480848).

Condition:   Atherosclerosis
Interventions:   Drug: Darapladib;   Drug: Diltiazem
Sponsor:   GlaxoSmithKline
Completed - verified July 2017

Evaluation of Lysine-Specific Demethylase 1

Condition:   Hypertension
Interventions:   Drug: Para-aminohippuric Acid;   Drug: Angiotensin II
Sponsor:   Brigham and Women's Hospital
Withdrawn - verified July 2017

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

Conditions:   Asthma;   Atherosclerosis;   Metabolic Syndrome;   Insulin Resistance;   Cancer
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Enrolling by invitation - verified June 28, 2017

Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System

Condition:   Chronic Granulomatous Disease (CGD)
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified July 11, 2017

ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

Conditions:   Cardiovascular Disease;   Coronary Artery Calcification
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified June 30, 2017

Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection

Condition:   Job's Syndrome
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Albert Einstein College of Medicine, Inc.
Recruiting - verified July 11, 2017

Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS)

Conditions:   Cardiovascular Diseases;   Coronary Arteriosclerosis;   Coronary Disease;   Heart Diseases;   Myocardial Infarction;   Myocardial Ischemia
Interventions:   Behavioral: dietary supplements;   Drug: vitamin C;   Drug: vitamin E;   Drug: beta-carotene;   Drug: folic acid/Vitamin B6/Vitamin B12
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified July 2017