Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Gestational Diabetes on Offspring's Cardiovascular Health: MySweetHeart Cohort

Conditions:   Cardiovascular Diseases;   Gestational Diabetes Mellitus
Intervention:   Other: GDM
Sponsor:   University of Lausanne Hospitals
Not yet recruiting - verified August 2016

Contrast Ultrasound Assessment of Perfusion Changes After Peripheral Artery Revascularization

Condition:   Peripheral Artery Disease
Intervention:   Other: Contrast ultrasound perfusion imaging of the limb
Sponsor:   Oregon Health and Science University
Not yet recruiting - verified August 2016

Walking Training in Peripheral Artery Disease (GrEnADa Sub-study)

Conditions:   Peripheral Artery Disease;   Intermittent Claudication
Interventions:   Other: Stretching exercise group;   Other: Walking training group
Sponsor:   Katholieke Universiteit Leuven
Not yet recruiting - verified August 2016

Exercise in Peripheral Artery Disease

Conditions:   Peripheral Artery Disease;   Intermittent Claudication
Interventions:   Other: No intervention (Observational study);   Other: Control session;   Other: Exercise session
Sponsor:   Katholieke Universiteit Leuven
Not yet recruiting - verified August 2016

MyoVista Measurements in Patients With Atherosclerosis and CAD

Conditions:   Coronary Artery Disease (CAD);   Atherosclerosis
Intervention:   Device: MyoVista
Sponsors:   Los Angeles Biomedical Research Institute;   Heart Test Laboratories Inc.
Recruiting - verified August 2016

Tack Optimized Drug Coated Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries

Condition:   Peripheral Arterial Disease
Intervention:   Device: Tack Endovascular System
Sponsor:   Intact Vascular
Recruiting - verified August 2016

The DESappear Study: Drug Eluting Scaffold

Condition:   Peripheral Vascular Disease
Intervention:   Device: Akesys Prava Scaffold
Sponsors:   Elixir Medical Corporation;   Syntactx;   Massachusetts General Hospital
Not yet recruiting - verified August 2016

Coronary Flow Reserve to Assess Cardiovascular Inflammation (CIRT-CFR)

Conditions:   Coronary Heart Disease;   Metabolic Syndrome;   Diabetes Mellitus
Interventions:   Radiation: PET scan;   Radiation: Echocardiogram
Sponsors:   Brigham and Women's Hospital;   Ottawa Heart Institute Research Corporation;   University of Alabama at Birmingham
Recruiting - verified August 2016

Cocoa to Improve Walking Performance in Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Cocoa;   Drug: Placebo
Sponsors:   Northwestern University;   National Institute on Aging (NIA)
Not yet recruiting - verified August 2016

Comparison of the Vasomotor Function and Myocardial Flow in Patients Treated With Bioresorbable and Metallic Stents at 1 Year

Condition:   Stable Angina
Interventions:   Device: Bioresorbable vascular scaffold;   Device: Everolimus-eluting stent
Sponsors:   Institut d'Investigació Biomèdica de Bellvitge;   Fundació La Marató de TV3
Recruiting - verified August 2016

Korean Post-market Registry Assessing the Clinical Use and Safety of the Lutonix DCB in Femoropopliteal Arteries

Condition:   Peripheral Artery Disease
Intervention:  
Sponsor:   C. R. Bard
Recruiting - verified March 2016

Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study

Conditions:   Vascular Inflammation;   Atherosclerotic Cardiovascular Disease
Interventions:   Drug: Low dose methotrexate;   Drug: Placebo
Sponsors:   Icahn School of Medicine at Mount Sinai;   Brigham and Women's Hospital;   Massachusetts General Hospital;   St. Michael's Hospital, Toronto;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

Angioplasty + SBCV vs. Angioplasty Alone for Femoropopliteal Artery Stenosis

Condition:   Peripheral Arterial Disease
Interventions:   Other: SBCV;   Other: Saline
Sponsors:   Symic Vascular;   Symic Biomedical, Inc.
Recruiting - verified August 2016

A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical Atherosclerosis

Condition:   Atherosclerosis
Interventions:   Drug: Rosuvastatin;   Drug: Placebo
Sponsor:   AstraZeneca
Recruiting - verified August 2016

Beneficial Effects of the Amino-acid Food Supplement L-Citrulline in Participants With Peripheral Artery Disease

Condition:   Peripheral Arterial Disease
Interventions:   Dietary Supplement: L-citrulline;   Dietary Supplement: Placebo
Sponsors:   Maastricht University;   Clinical Trial Center Maastricht;   Catharina Ziekenhuis Eindhoven;   Hannover Medical School
Recruiting - verified August 2016

Tack Optimized Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries

Condition:   Peripheral Artery Disease
Intervention:   Device: Tack Endovascular System
Sponsor:   Intact Vascular
Recruiting - verified August 2016

Comparison of Prevena Negative Pressure Incision Management System vs. Standard Dressing After Vascular Surgery

Conditions:   Peripheral Artery Disease;   Critical Limb Ischemia;   Claudication
Interventions:   Other: standard gauze dressing;   Other: Prevena Incision Management system
Sponsors:   University of Vermont Medical Center;   KCI USA, Inc.;   Maine Medical Center;   Brigham and Women's Hospital;   Beth Israel Deaconess Medical Center
Recruiting - verified August 2016

Genes Involved in Lipid Disorders

Condition:   Dyslipidemia
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2016

Effect of Cilostazol on Coronary Artery Stenosis and Plaque Characteristics in Patients With T2DM

Condition:   Coronary Artery Disease
Interventions:   Drug: Cilostazol;   Drug: Aspirin
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified August 2016

EARly Prevention of aTHeroma Progression

Condition:   Coronary Arteriosclerosis
Interventions:   Behavioral: Standard Therapy;   Drug: Rosuvastatin
Sponsors:   CHEOL WHAN LEE, M.D., Ph.D;   CardioVascular Research Foundation, Korea
Active, not recruiting - verified August 2016

Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography

Conditions:   Atherosclerosis;   Stroke;   Transient Ischemic Attack;   Chronic Stable Angina;   Acute Coronary Syndrome
Intervention:  
Sponsor:   University of Cambridge
Completed - verified August 2016

Study of the Effects of Blackcurrant Extract and Omega-3 Fats on the Health of the Heart and Blood Vessels

Conditions:   Abnormalities;   Hyperlipidemia;   Cardiovascular Disease;   Arteriosclerosis
Intervention:  
Sponsors:   National Institute of Nursing Research (NINR);   Tufts University
Recruiting - verified November 2015

A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb Ischemia

Conditions:   Critical Limb Ischemia;   Vascular Diseases;   Peripheral Arterial Disease
Intervention:   Genetic: HGF Plasmid
Sponsor:   AnGes
Active, not recruiting - verified August 2016

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Completed - verified August 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified August 2016

Evaluation of the Safety and Efficacy of a Vascular Prosthesis as an Above-Knee Bypass Graft in Patients With PAD

Conditions:   Peripheral Arterial Disease;   Peripheral Vascular Disease
Intervention:   Device: HAVG graft implantation
Sponsors:   Humacyte, Inc.;   FGK Clinical Research Sp. zo.o.;   FGK Clinical Research GmbH
Active, not recruiting - verified August 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified August 2016

Near-Infrared Spectroscopy and Ultrasound Investigation of Coronary Artery Plaque

Conditions:   Coronary Artery Disease;   Atherosclerosis
Intervention:   Device: NIRS/IVUS of coronary artery
Sponsor:   Simon Dixon, MD
Withdrawn - verified August 2016

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified August 2016

Paclitaxel Eluting Stent in Long SFA Obstruction: A Prospective, Randomized Comparison With Bypass Surgery

Conditions:   Chronic Lower Limb Ischemia;   Peripheral Athero Obstructive Disease;   Critical Ischemia;   Claudication
Interventions:   Procedure: bypass surgery, stent placement;   Procedure: stent placement
Sponsors:   Kuopio University Hospital;   Helsinki University Central Hospital;   Turku University Hospital;   Tampere University Hospital;   Oulu University Hospital;   Finnish Society of Interventional radiology;   North Karelia Central Hospital;   Paijat-Hame Hospital District
Recruiting - verified June 2016

Modulation of Monocyte Activation by Atorvastatin in HIV Infection

Condition:   HIV Dementia
Intervention:   Drug: Atorvastatin
Sponsors:   University of Pennsylvania;   National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting - verified August 2016

Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China

Condition:   Esophageal Cancer
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Completed - verified September 2015

Joint Determinants of Bone Density and CVD Calcification

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Osteoporosis
Intervention:  
Sponsors:   University of Maryland;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008

Molecular & Clinical Evaluation of Low HDL Syndromes

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Atherosclerosis
Intervention:  
Sponsors:   University of Maryland;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008