Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Different Doses of Rosuvastatin Therapy on Regression of Critical Coronary Atherosclerosis in ACS Patients

Condition:   Acute Coronary Syndrome
Intervention:   Drug: rosuvastatin
Sponsor:   Beijing Friendship Hospital
Not yet recruiting - verified April 2015

PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis

Condition:   Carotid Atherosclerosis
Intervention:   Device: Cu[64]-25%-CANF-Comb PET-MR
Sponsor:   Washington University School of Medicine
Recruiting - verified April 2015

Nutraceutical Combination in Patients With Low-grade Systemic Inflammation

Conditions:   Atherosclerosis;   Inflammation;   Hypercholesterolemia
Interventions:   Dietary Supplement: Nutraceutical Combination;   Other: Standard of Care;   Other: Placebo
Sponsor:   University Of Perugia
Completed - verified April 2015

Efficacy of Ranolazine in Patients With Chronic Total Occlusions of Coronary Arteries

Conditions:   Myocardial Ischemia;   Coronary Artery Disease;   Arteriosclerosis;   Chronic Stable Angina
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsors:   East Carolina University;   Gilead Sciences
Not yet recruiting - verified April 2015

Women's Health Initiative Strong and Healthy Study

Conditions:   Myocardial Infarction;   Stroke;   Cardiovascular Mortality;   Hip Fractures;   Falls;   Mortality;   Venous Thromboembolic Event;   Peripheral Artery Disease
Intervention:   Behavioral: Physical Activity
Sponsors:   Fred Hutchinson Cancer Research Center;   University of California, San Diego;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified April 2015

Non-contrast Cardiac CT as a Risk Stratification Tool in Patients With Non-cardiac Chest Pain

Condition:   Coronary Artery Disease
Intervention:   Other: Non-contrast Cardiac CT scan
Sponsor:   University of Southern Denmark
Recruiting - verified April 2015

An Epidemiological Cohort Study of Acute Coronary Syndromes in The Greek Population. The PHAETHON Study

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Hellenic Cardiovascular Research Society
Completed - verified April 2015

Effects of Eicosapentaenoic Acid on Endothelial Function in Diabetic Subjects

Conditions:   Type 2 Diabetes;   Coronary Artery Disease
Intervention:   Drug: Icosapent ethyl
Sponsor:   Brigham and Women's Hospital
Not yet recruiting - verified April 2015

Medtronic Resolute Onyx Core (2.25 mm - 4.0 mm) Clinical Study

Condition:   Coronary Artery Disease
Intervention:   Device: Resolute Onyx Stent - 2.25 mm - 4.0 mm
Sponsor:   Medtronic Vascular
Not yet recruiting - verified April 2015

A Study on the Use of CorMatrix ®ECM® for Femoral Arterial Reconstruction

Condition:   Peripheral Vascular Disease
Intervention:   Device: CorMatrix ECM for Vascular Repair
Sponsor:   CorMatrix
Not yet recruiting - verified April 2015

A Study to Obtain Additional Information on the Use of CorMatrix® CanGaroo ECM® Envelope

Condition:   Coronary Disease
Intervention:   Device: CorMatrix CanGaroo ECM Envelope
Sponsor:   CorMatrix
Not yet recruiting - verified April 2015

Vascular Ultrasound Screening in Patients With Ischemic Cerebrovascular Disease: a Multi-center Registry Study

Condition:   Stroke
Intervention:  
Sponsors:   Xuanwu Hospital, Beijing;   The First Affiliated Hospital of Shanxi Medical University;   Liaocheng Brains Hospital;   Tianjin Huanhu Hospital;   Baotou City Central Hospital;   First Hospital of Jilin University;   First Affiliated Hospital of Harbin Medical University;   First Hospital of China Medical University;   LanZhou University;   First Affiliated Hospital of Xinjiang Medical University;   The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School;   The First Affiliated Hospital of Soochow University;   Anhui Provincial Hospital;   Guangdong Provincial Hospital of Traditional Chinese Medicine;   Zhuhai  People's Hospital;   Fujian Provincial Hospital;   Mianyang Central Hospital;   The Second Affiliated Hospital of Kunming Medical University;   Brains Hospital of Hunan Province;   Henan Provincial Hospital;   Luoyang Central Hospital Affiliated to Zhengzhou University;   National Health and Family Planning Commission Stroke Prevention Engineering Committee
Not yet recruiting - verified March 2015

Medtronic Resolute Onyx 2.0 mm Clinical Study

Condition:   Coronary Artery Disease
Intervention:   Device: Resolute Onyx Stent - 2.0 mm
Sponsor:   Medtronic Vascular
Not yet recruiting - verified April 2015

Changes in the Risk Factors of Coronary Heart Disease Observed After Scaling and Root Planing

Conditions:   Coronary Heart Disease;   Periodontitis
Interventions:   Device: piezoelectric ultrasonic scaler (frequency of 28-36 KHz);   Device: Gracey curettes
Sponsor:   Government College of Dentistry, Indore
Completed - verified April 2015

The Impact of Rosuvastatin on the Density Score of Coronary Artery Calcification in CAD Patients With Diabetes Mellitus

Condition:   Coronary Artery Disease
Intervention:   Drug: rosuvastatin
Sponsor:   Sir Run Run Shaw Hospital
Not yet recruiting - verified April 2015

Metabolic, Vascular and Cognitive Effects of Treatment With Anthocyanins

Conditions:   Coronary Disease;   Inflammation;   Cognitive Impairment
Intervention:   Dietary Supplement: Anthocyanin
Sponsor:   Helse Stavanger HF
Recruiting - verified April 2015

Antithrombotic Strategy Variability In ATrial Fibrillation and Obstructive Coronary Disease Revascularized With PCI - The AVIATOR 2 Registry

Condition:   Non-valvular Atrial Fibrillation
Intervention:  
Sponsors:   Mount Sinai School of Medicine;   Bristol-Myers Squibb
Recruiting - verified April 2015

Atherosclerotic Plaque Characteristics Associated With a Progression Rate of the Plaque in Carotids and a Risk of Stroke

Condition:   Carotid Artery Plaque
Intervention:  
Sponsors:   University Hospital Ostrava;   General Teaching Hospital, Prague;   Charles University, Czech Republic;   Palacky University
Recruiting - verified April 2015

"In Vivo" Comparison in Human Carotid Atherosclerosis: Plaque Neovascularization

Conditions:   Carotid Artery Disease;   Plaque Neovascularization
Interventions:   Other: Contrast enhanced ultrasound of the carotid plaque;   Other: Dynamic contrast-enhanced carotid plaque MRI
Sponsor:   Ospedale San Giovanni Bellinzona
Recruiting - verified April 2015

Outcome After Coronary Artery Bypass Grafting

Conditions:   Coronary Artery Disease;   Myocardial Infarction;   Angina Pectoris
Intervention:   Procedure: Coronary artery bypass surgery
Sponsors:   University of Oulu;   Universita di Verona;   Ospedali Riuniti Trieste;   University of Catania;   University of Leicester;   Centre Hospitalier Universitaire de Besancon;   Karolinska Institutet;   San Camillo Hospital, Rome;   Rennes University Hospital;   S. Anna Hospital;   Paracelsus Medical University;   Second University of Naples;   University of Parma
Recruiting - verified April 2015

A Clinical Trial on the Effects of Home-based Five Plus Exercise Training

Condition:   Intermittent Claudication
Intervention:   Other: Five plus exercise training
Sponsor:   Norwegian University of Science and Technology
Active, not recruiting - verified April 2015

BIOLUX P-III All-Comers Passeo-18 Lux Registry

Conditions:   Atherosclerosis;   Peripheral Artery Disease
Intervention:   Device: Passeo-18 Lux
Sponsor:   Biotronik AG
Recruiting - verified April 2015

Zilver PTX Delivery System

Condition:   Peripheral Vascular Disease
Intervention:   Device: Zilver® PTX® Drug-Eluting Peripheral Stent
Sponsor:   Cook
Recruiting - verified April 2015

Removal of Cytokines During Extracorporeal Circulation in Cardiac Surgery

Conditions:   Coronary Artery Disease;   Heart Valve Diseases
Intervention:   Device: CytoSorb device
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Recruiting - verified April 2015

BFPET for Regional Myocardial Perfusion Imaging

Condition:   Coronary Artery Disease
Intervention:   Drug: BFPET
Sponsor:   Fluoropharma, Inc.
Recruiting - verified April 2015

AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome)

Conditions:   Turner Syndrome;   Peripheral Angiopathy;   Vascular Malformation;   Lymphedema
Intervention:   Procedure: Echo doppler
Sponsor:   University Hospital, Strasbourg, France
Recruiting - verified April 2015

Coronary CT Angiography Using a Novel 3rd Generation Dual-Source CT System

Condition:   Coronary Artery Disease
Interventions:   Procedure: Coronary CT angiography on SOMATOM Force;   Procedure: Previous coronary CT angiography on 2nd generation CT scanner
Sponsor:   U. Josepf Schoepf, MD
Recruiting - verified April 2015

Intravascular Ultrasound Guided Drug Eluting Stent Implantation in "All-comers" Coronary Lesions

Condition:   Coronary Artery Disease
Interventions:   Procedure: Angiography;   Procedure: IVUS;   Procedure: DES implantation
Sponsor:   The First Hospital of Nanjing Medical University
Recruiting - verified April 2015

Colchicine in Vascular Inflammation Assessed With PET Imaging

Condition:   Atherosclerotic Vascular Disease
Intervention:   Drug: Colchicine
Sponsor:   Montreal Heart Institute
Active, not recruiting - verified April 2015

Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study Of PF-06291874 As Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type II
Interventions:   Drug: Placebo;   Drug: PF-06291874;   Drug: PF-06291874;   Drug: PF-06291874;   Drug: PF-06291874
Sponsor:   Pfizer
Completed - verified April 2015

Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Rilapladib (SB659032) in Healthy Volunteers

Condition:   Alzheimer's Disease
Interventions:   Drug: Rilapladib 25 mg;   Drug: Rilapladib 250 mg;   Drug: Itraconazole
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified April 2015

A Human In Vivo Feeding Study Of The Blood Monocyte Response To Dietary Lipid Intake

Condition:   Atherosclerosis
Interventions:   Dietary Supplement: Mixed High Fat Diet;   Dietary Supplement: Saturated fat diet;   Dietary Supplement: Monounsaturated fat diet;   Dietary Supplement: Polyunsaturated fat diet;   Dietary Supplement: Triolein 13C;   Dietary Supplement: Low fat
Sponsor:   Imperial College London
Recruiting - verified March 2014

Computed Tomography and Biomarker Analysis in Diagnosing Coronary Artery Disease in Asymptomatic Patients Who Have Undergone Stem Cell Transplant

Conditions:   Cancer Survivor;   Diabetes Mellitus;   Hypertension
Interventions:   Procedure: computed tomography;   Other: cytology specimen collection procedure;   Other: laboratory biomarker analysis;   Other: questionnaire administration
Sponsors:   City of Hope Medical Center;   National Cancer Institute (NCI)
Completed - verified April 2015

Angioshield First-In-Human Study to Demonstrate the Preliminary Safety and Efficacy

Condition:   Coronary Artery Disease
Intervention:   Device: Angioshield
Sponsor:   Neograft Technologies, Incorporated
Active, not recruiting - verified April 2015

Obtain Additional Information on Use of CorMatrix ECM (Extracellular Matrix)

Condition:   Coronary Disease
Intervention:  
Sponsor:   CorMatrix
Enrolling by invitation - verified April 2015

Compare Ticagrelor vs Clopidogrel on the Reduction of Arterial Stiffness and Wave Reflectionsin Patients With Coronary Artery Disease . The NOVELTY Study

Condition:   Coronary Artery Disease
Intervention:   Drug: Ticagrelor
Sponsors:   Hellenic Cardiovascular Research Society;   AstraZeneca
Recruiting - verified April 2015

Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease

Conditions:   Myocardial Infarction;   Ischemic Stroke;   Stroke;   Subarachnoid Haemorrhage;   Venous Thrombosis;   Transient Ischemic Attack;   Stable Angina Pectoris;   Unstable Angina;   Heart Failure;   Peripheral Arterial Disease;   Abdominal Aortic Aneurysm
Intervention:   Other: No intervention
Sponsors:   University College, London;   Wellcome Trust;   National Institute for Health Research, United Kingdom
Active, not recruiting - verified April 2015

Post Market Surveillance Study of the Wingspan Stent System

Condition:   Intracranial Atherosclerosis
Intervention:   Device: Wingspan Stent System
Sponsor:   Stryker Neurovascular
Recruiting - verified April 2015

Supplementation With Polyphenol-Rich Foods and Atrial Fibrillation After a Cardiac Surgery

Condition:   Coronary Heart Disease
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: High-anthocyanin rich corn flour
Sponsor:   Neuromed IRCCS
Recruiting - verified April 2015

Reduction in Infarct Size by Remote Per-postconditioning in Patients With ST-elevation Myocardial Infarction

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:   Procedure: Primary Percutaneous Coronary Intervention
Sponsor:   John Pernow
Recruiting - verified April 2015

Arginase Inhibition in Ischemia-reperfusion Injury

Conditions:   Coronary Artery Disease;   Type 2 Diabetes Mellitus
Interventions:   Drug: N-hydroxy-nor-arginine;   Drug: NaCl
Sponsor:   Karolinska Institutet
Completed - verified April 2015

ISCHEMIA-Chronic Kidney Disease Trial

Conditions:   Cardiovascular Diseases;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia;   Kidney Disease;   End Stage Renal Failure on Dialysis
Interventions:   Procedure: Cardiac Catheterization;   Procedure: Coronary Artery Bypass Graft Surgery;   Procedure: Percutaneous Coronary Intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   New York University School of Medicine;   New York University;   National Heart, Lung, and Blood Institute (NHLBI);   Vanderbilt University;   Albany Stratton VA Medical Center;   East Carolina University;   Duke University;   Stanford University;   Harvard University;   Columbia University
Recruiting - verified April 2015

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Recruiting - verified April 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified April 2015

Relationship Between CETP Deficiency and Atherosclerosis in Patients With Hyperalphalipoproteinemia

Conditions:   Low CETP Activity;   CETP Deficiency;   Hyperalphalipoproteinemia;   Hyper-LDL-cholesterolemia;   High Level of Remnant Cholesterol
Intervention:  
Sponsors:   Osaka University;   Merck Sharp & Dohme Corp.
Recruiting - verified August 2013

Xenon as an Adjuvant to Propofol Anaesthesia in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery.

Conditions:   Coronary Artery Disease;   Anesthesia
Interventions:   Drug: Xenon and propofol;   Drug: propofol
Sponsor:   Universitaire Ziekenhuizen Leuven
Completed - verified April 2015

Correlation Between Coronary and Carotid Atherosclerotic Disease and Links With Clinical Outcomes

Condition:   Vascular Disease
Intervention:  
Sponsor:   Montreal Heart Institute
Recruiting - verified April 2015

Resolute Integrity US Extended Length Sub-Study(RI-US XL)

Condition:   Coronary Artery Disease
Intervention:   Device: Resolute Integrity Stent
Sponsor:   Medtronic Vascular
Recruiting - verified April 2015

Non-isotope Based Imaging Modalities vs Technetium-99m Single-Photon Emission Computed Tomography(99mTcSPECT)

Condition:   Myocardial Ischemia
Intervention:  
Sponsors:   Montreal Heart Institute;   Canadian Institutes of Health Research  (CIHR)
Recruiting - verified April 2015

Screening and Access to Health Care for Vascular Disease

Conditions:   Aortic Aneurysm, Abdominal;   Carotid Stenosis;   Peripheral Arterial Disease
Intervention:  
Sponsors:   NavYash Gupta, MD;   Medtronic
Active, not recruiting - verified April 2015

Walnut Consumption, Endothelial Function, and Biomarkers

Conditions:   Coronary Heart Disease;   Type 2 Diabetes
Intervention:   Other: Once ounce per day of walnuts
Sponsor:   Brigham and Women's Hospital
Active, not recruiting - verified April 2015

Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque

Conditions:   Atherosclerosis;   Atherosclerotic Plaque;   Carotid Stenosis
Intervention:   Drug: Indocyanine green
Sponsor:   Massachusetts General Hospital
Recruiting - verified April 2015

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified April 2015

Comparative Effectiveness of Stress Tests

Condition:   Coronary Artery Disease
Intervention:   Other: Diagnostic Cardiac Imaging
Sponsor:   Jennifer Dickerson
Recruiting - verified April 2015

AVJ-301 Clinical Trial: A Clinical Evaluation of AVJ-301 (Absorb™ BVS) in Japanese Population

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Interventions:   Device: XIENCE PRIME®/XIENCE Xpedition™;   Device: Absorb™ BVS
Sponsor:   Abbott Vascular
Active, not recruiting - verified April 2015

Impact of Perivascular Tissue on Endothelial Function in Coronary Artery Bypass Grafting

Condition:   Myocardial Ischemia
Interventions:   Procedure: no-touch;   Procedure: conventional
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital
Completed - verified April 2015

Stenting of the Superficial Femoral and/or Proximal Popliteal Artery Project

Condition:   Atherosclerosis of Native Arteries of the Extremities
Intervention:   Device: The Boston Scientific DES SFA Paclitaxel-Eluting Self-Expanding Stent System (DES SFA)
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified April 2015

Sirolimus Eluting ORSIRO Stent Versus Biolimus-eluting NOBORI Stent

Conditions:   Coronary Artery Disease;   Ischemic Heart Disease
Intervention:   Device: Drug-eluting stent
Sponsor:   Odense University Hospital
Active, not recruiting - verified April 2015

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified April 2015

An Evaluation of the Commercially Available Medtronic Resolute Integrity Zotarolimus-Eluting Coronary Stent System

Condition:   Coronary Artery Disease
Intervention:   Procedure: Medtronic Resolute Integrity Zotarolimus-Eluting Coronary Stent System (Resolute Integrity Stent)
Sponsor:   Medtronic Vascular
Active, not recruiting - verified April 2015

Prevention Trial to Achieve Cardiovascular Targets

Conditions:   Coronary Artery Disease;   Peripheral Arterial Disease;   Hyperlipidemia;   Hypertension;   Diabetes;   Prediabetes;   Obesity
Interventions:   Behavioral: Prevention Consult;   Behavioral: Consult & Behavioral Intervention
Sponsors:   New York University School of Medicine;   The Rainer Arnhold Foundation
Recruiting - verified April 2015

Anti-INFLammatory to Address Mood and Endothelial Dysfunction (INFLAMED)

Conditions:   Major Depressive Disorder;   Depression;   Depressive Symptoms;   Cardiovascular Disease (CVD);   Coronary Artery Disease (CAD);   Heart Disease
Interventions:   Drug: Pentoxifylline;   Other: Placebo;   Behavioral: Standard Treatment
Sponsors:   Indiana University;   National Institute of Mental Health (NIMH)
Completed - verified April 2015

Pilot Study of PRT-201 Following Angioplasty in Patients With Peripheral Artery Disease (PAD)

Condition:   Peripheral Artery Disease
Intervention:   Drug: PRT-201
Sponsors:   Proteon Therapeutics;   University of California, San Francisco
Active, not recruiting - verified April 2015

The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes

Conditions:   Coronary Artery Disease;   Diabetes Mellitus, Type 2
Interventions:   Drug: Liraglutide;   Drug: Placebo
Sponsor:   Haugaard, Steen Bendix, M.D., DMSc
Active, not recruiting - verified April 2015

Exercise Cardiac Magnetic Resonance Imaging Accuracy for Cardiovascular Stress Testing

Condition:   Coronary Artery Disease
Intervention:   Other: Diagnostic Cardiac Imaging
Sponsor:   Jennifer Dickerson
Active, not recruiting - verified April 2015

ABSORB II Randomized Controlled Trial

Condition:   Coronary Artery Disease
Interventions:   Device: Abbott Vascular XIENCE Everolimus Eluting Coronary Stent System;   Device: Abbott Vascular ABSORB Everolimus Eluting Bioresorbable Vascular Scaffold System
Sponsor:   Abbott Vascular
Active, not recruiting - verified April 2015

Patient-centered Outcomes Related to TReatment Practices in Peripheral Arterial Disease: Investigating Trajectories (PORTRAIT)

Conditions:   Peripheral Arterial Disease;   Quality of Life;   Quality of Care
Intervention:  
Sponsors:   Saint Luke's Health System;   Patient Centered Outcome Research Institute
Recruiting - verified April 2015

Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:  
Sponsors:   Columbia University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified April 2015

The Role Of Noninvasive 320-Row Multidetector Computer Tomography

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   University Health Network, Toronto;   Mount Sinai Hospital, Canada
Active, not recruiting - verified April 2015

Comparison Between FFR Guided Revascularization Versus Conventional Strategy in Acute STEMI Patients With MVD.

Conditions:   Myocardial Infarction;   Multivessel Coronary Artery Disease
Interventions:   Procedure: FFR-guided revascularisation strategy;   Procedure: randomised to guidelines group
Sponsors:   Maasstad Hospital;   Abbott Vascular;   St. Jude Medical
Recruiting - verified April 2015

Resolute Zotarolimus-Eluting Stent Versus the Taxus Liberte Paclitaxel-Eluting Stent for Percutaneous Coronary Intervention in China

Conditions:   Ischemic Heart Disease;   Stenotic Coronary Lesion;   Cardiovascular Diseases;   Arteriosclerosis;   Coronary Artery Disease
Interventions:   Device: Taxus Liberte Paclitaxel-Eluting Coronary Stent System;   Device: Resolute Zotarolimus-Eluting Coronary Stent System
Sponsor:   Medtronic Vascular
Active, not recruiting - verified April 2015

Evaluation of the Endeavor Resolute Zotarolimus-Eluting Coronary Stent System in a Real-World Patient Population in China

Conditions:   Ischemic Heart Disease;   Stenotic Coronary Lesion;   Cardiovascular Diseases;   Arteriosclerosis;   Coronary Artery Disease
Intervention:  
Sponsor:   Medtronic Vascular
Active, not recruiting - verified April 2015

Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis

Conditions:   Aortocoronary Saphenous Vein Bypass Graft Atherosclerosis;   Intermediate Saphenous Vein Graft Lesions
Intervention:   Drug: extended-release niacin (Niaspan)
Sponsors:   North Texas Veterans Healthcare System;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified April 2015

EXCEL Clinical Trial

Conditions:   Chronic Coronary Occlusion;   Unprotected Left Main Coronary Artery Disease;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Interventions:   Device: Percutaneous Coronary Intervention;   Procedure: CABG
Sponsor:   Abbott Vascular
Active, not recruiting - verified April 2015

Vitamin D Supplementation in CAD and Postchallenge Hyperglycemia

Conditions:   Coronary Artery Disease;   Postprandial Hyperglycemia;   Vitamin D Deficiency
Intervention:   Drug: vitamin D
Sponsor:   Medical University of Graz
Terminated - verified April 2015

RESOLUTE Asia: Evaluation of the Endeavor Resolute Zotarolimus-Eluting Stent System in a Patient Population With Long Lesion(s) and/or Dual Vessels in Asia

Conditions:   Ischemic Heart Disease;   Stenotic Coronary Lesion;   Cardiovascular Diseases;   Arteriosclerosis;   Coronary Artery Disease
Intervention:   Device: Drug eluting stent treatment
Sponsor:   Medtronic Vascular
Active, not recruiting - verified April 2015

Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft Angioplasty

Condition:   Saphenous Vein Graft Atherosclerosis
Interventions:   Device: Bare Metal Stent;   Device: Drug-Eluting Stent;   Drug: Blinded clopidogrel;   Drug: Placebo;   Drug: Thienopyridine (open-label)
Sponsor:   Department of Veterans Affairs
Recruiting - verified April 2015

Troponin T as Risk Stratification Tool in Peripheral Arterial Occlusive Disease

Condition:   Peripheral Arterial Occlusive Disease
Intervention:  
Sponsors:   Heart Center Bad Krozingen;   Johann Wolfgang Goethe University Hospitals
Completed - verified April 2015

XIENCE V/PROMUS Everolimus-Eluting Stent System Post-marketing Surveillance Protocol for Japan

Conditions:   Angina;   Chronic Coronary Occlusion;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Intervention:   Device: XIENCE V / PROMUS stent
Sponsor:   Abbott Vascular
Active, not recruiting - verified April 2015

Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System

Condition:   Chronic Granulomatous Disease (CGD)
Intervention:  
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified May 2014

Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With High Cholesterol (P03434)

Conditions:   Hypercholesterolemia;   Atherosclerosis
Interventions:   Drug: Ezetimibe + Atorvastatin;   Drug: Atorvastatin
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified April 2015

Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)

Conditions:   Hypercholesterolaemia;   Atherosclerosis
Interventions:   Drug: Ezetimibe + Simvastatin;   Drug: Simvastatin
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified April 2015

Effect of Ezetimibe Plus Simvastatin on Flow-Mediated Brachial Artery Vasoactivity in Subjects With Primary Hypercholesterolemia (Study P03336)

Conditions:   Hypercholesterolemia;   Atherosclerosis
Interventions:   Drug: Ezetimibe + Simvastatin;   Drug: Simvastatin;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Terminated - verified April 2015

Assessment of Potential Interaction Between Ezetimibe and Rosuvastatin in Healthy Subjects With High Cholesterol (P03317)

Conditions:   Hypercholesterolemia;   Atherosclerosis
Interventions:   Drug: Ezetimibe + Rosuvastatin;   Drug: Rosuvastatin;   Drug: Placebo;   Drug: Ezetimibe
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified April 2015

Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)

Conditions:   Hypercholesterolemia;   Atherosclerosis
Interventions:   Drug: Ezetimibe;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Merck Frosst Canada Ltd.
Terminated - verified April 2015

Comparison of Co-administration of Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Primary Hypercholesterolemia (P03476)

Conditions:   Atherosclerosis;   Hypercholesterolemia;   Coronary Heart Disease
Interventions:   Drug: Ezetimibe;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified April 2015

Study to Test the Efficacy and Safety of Drug Eluting vs. Bare-Metal Stents for Saphenous Vein Graft Interventions

Condition:   Coronary Artery Disease
Interventions:   Device: Drug eluting stent;   Device: Bare metal stent
Sponsors:   University Hospital, Basel, Switzerland;   University of Leipzig
Terminated - verified April 2015

Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578)

Conditions:   Atherosclerosis;   Hypercholesterolemia;   Hyperlipoproteinemia Type II
Interventions:   Drug: ezetimibe (plus simvastatin);   Drug: placebo (plus simvastatin)
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified April 2015

A Trial Using CD133 Enriched Bone Marrow Cells Following Primary Angioplasty for Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Other: CD133+ infusion;   Other: placebo infusion
Sponsors:   Jozef Bartunek;   King's College London
Terminated - verified April 2015

The Effect of Training on Endothelial Function, Progression of Disease,Inflammation, Heart Rate Variability and Mental Health After Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Intervention:   Behavioral: exercise training
Sponsor:   Helse Stavanger HF
Completed - verified February 2009

RESPECT PFO Clinical Trial

Condition:   Cryptogenic Stroke
Interventions:   Device: AMPLATZER PFO Occluder;   Other: Standard of Care - Medical Management
Sponsor:   St. Jude Medical
Active, not recruiting - verified April 2015

The Diagnostic Benefits of the HyperQTM System in ECG Stress Testing

Condition:   Myocardial Ischemia
Intervention:   Device: Excercise stress test with high frequency ECG recording (HyperQ™ System)
Sponsors:   Assuta Hospital Systems;   BSP Biological Signal Processing Ltd.
Recruiting - verified October 2006

Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST)

Conditions:   Coronary Arteriosclerosis;   Diabetes Mellitus, Type 2;   Cerebrovascular Accident;   Dyslipidemia;   Peripheral Vascular Disease
Intervention:   Drug: Atorvastatin (Lipitor)
Sponsor:   Pfizer
Completed - verified April 2015

Cardiac Rehabilitation for the Treatment of Refractory Angina

Conditions:   Angina Pectoris;   Coronary Disease
Intervention:   Behavioral: Cardiac rehabilitation
Sponsors:   National Heart and Lung Institute;   British Heart Foundation;   Royal Brompton & Harefield NHS Foundation Trust
Completed - verified April 2015

Effect Of Rilapladib (SB-659032) On Platelet Aggregation

Conditions:   Healthy Subjects;   Atherosclerosis
Intervention:   Drug: Rilapladib (SB-659032)
Sponsor:   GlaxoSmithKline
Completed - verified April 2015

PET and Recovery Following Revascularization (PARR 2)

Conditions:   Coronary Artery Disease;   Ventricular Dysfunction, Left
Interventions:   Procedure: Positron emission tomography: FDG viability imaging;   Other: PET imaging
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research  (CIHR);   Heart and Stroke Foundation of Ontario
Completed - verified April 2015

Effects Of Atorvastatin On Macrophage Activity And Plaque Inflammation Using Magnetic Resonance Imaging

Conditions:   Atherosclerotic Carotid Disease;   Atheroma;   Atherosclerosis
Intervention:   Drug: atorvastatin
Sponsor:   GlaxoSmithKline
Completed - verified April 2015

Isoflavones and the Coronary Circulation in Men and Women With Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Drug: genistein (Supro)
Sponsor:   Imperial College London
Completed - verified February 2006

Endoscopic Vessel Harvesting During Coronary Bypass Surgery

Condition:   Coronary Arteriosclerosis
Intervention:   Procedure: vein harvest
Sponsor:   Aalborg Universitetshospital  
Completed - verified April 2015

Exercise-training Before Coronary Artery Bypass Graft (CABG)

Conditions:   Angina;   Coronary Artery Disease
Intervention:   Behavioral: Exercise training
Sponsor:   Norwegian University of Science and Technology
Recruiting - verified April 2015

Markers and Mechanisms of Macrovascular Disease in IDDM

Conditions:   Cardiovascular Diseases;   Diabetes Mellitus;   Atherosclerosis;   Heart Diseases;   Diabetes Mellitus, Insulin-dependent
Intervention:  
Sponsors:   Medical University of South Carolina;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 2008

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