Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Clinical and Laboratory Biomarkers in Patients With Atherothrombotic Stroke

Conditions:   Carotid Artery Diseases;   Stroke
Intervention:   Other: Biomarkers serum level measurement
Sponsor:   St. Petersburg State Pavlov Medical University
Recruiting - verified January 2015

Cardiovascular Epidemiology in Russian Federation

Conditions:   Hypertension;   Coronary Artery Disease;   Diabetes;   Heart Failure;   Smoking;   Lifestyle
Intervention:  
Sponsors:   Federal North-West Medical Research Centre;   National Research Center for Preventive Medicine;   Russian Cardiology Research and Production Center
Recruiting - verified May 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified May 2015

Efficacy and Safety of Tianzhi Granule in Mild to Moderate Vascular Dementia

Condition:   Vascular Dementia
Interventions:   Drug: Tianzhi granule;   Drug: Donepezil;   Drug: Placebo
Sponsor:   Dongzhimen Hospital, Beijing
Recruiting - verified May 2015

Vortioxetine in Patients With Major Depressive Disorder and Coronary Artery Disease

Conditions:   Major Depressive Disorder;   Coronary Artery Disease
Intervention:   Drug: Vortioxetine
Sponsors:   Thomas Jefferson University;   Takeda
Not yet recruiting - verified May 2015

Perfusion by Arterial Spin Labelling Following Single Dose Tadalafil in Small Vessel Disease (PASTIS) Trial

Condition:   Dementia, Vascular
Interventions:   Drug: Tadalafil;   Drug: Placebo;   Behavioral: Cognitive functioning tests;   Behavioral: Neuropsychological tests;   Other: MRI Scan - Arterial Spin Labelling
Sponsors:   St George's, University of London;   Alzheimer’s Drug Discovery Foundation;   Alzheimer's Society UK;   University of Copenhagen;   University of Glasgow
Not yet recruiting - verified March 2015

Acute Vascular Response to Exercise in Women With Nonobstructive Coronary Artery Disease

Condition:   Nonobstructive Coronary Artery Disease
Intervention:   Other: Slow-paced walking
Sponsor:   University of Florida
Not yet recruiting - verified May 2015

Acute Safety, Deliverability and Efficacy of the Medtronic Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System in the Treatment of Suitable Patients According to Indication for Use (CHINA RESOLUTE INTEGRITY STUDY)

Conditions:   Ischemic Heart Disease;   Cardiovascular Diseases;   Arteriosclerosis;   Coronary Artery Disease
Intervention:   Device: Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System
Sponsor:   Medtronic Vascular
Not yet recruiting - verified May 2015

A Prospective, Single-Blinded, Multi-Center, Randomized, Controlled, Registered Clinical Trial on the Efficacy and Safety of Sirolimus-Eluting Stent (MiStent® System) in the Treatment of Patients With Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Device: MiStentTM;   Device: TIVOLI
Sponsors:   Micell Technologies;   Hefei Life Science Medical Instruments Co. Ltd.;   Giant Med-Pharma Services Inc.;   CCRF Consulting Co., Ltd.
Not yet recruiting - verified May 2015

Plasma and Platelet microRNAs in Clopidogrel Low Response Patients

Condition:   Coronary Artery Disease
Interventions:   Drug: Clopidogrel;   Drug: acetylsalicylic acid (ASA)
Sponsors:   The First Hospital of Nanjing Medical University;   National Natural Science Foundation of China
Not yet recruiting - verified May 2015

Lowering Blood Pressure in Primary Care in Vienna

Condition:   Hypertension
Intervention:   Drug: Olmesartan medoxomil, amlodipine, hydrochlorothiazide
Sponsors:   Wilhelminenspital Vienna;   Association for the Promotion of Research in Atherosclerosis, Thrombosis and Vascular Biology ;   Ludwig Boltzmann Foundation for Cardiovascular Research
Recruiting - verified May 2015

Role of PPAR-y Anonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)

Condition:   Systemic Lupus Erthematosus
Interventions:   Radiation: PET/CT;   Drug: Pioglitazone;   Procedure: Vascular function studies
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting - verified December 2014

Liraglutide to Improve corONary Haemodynamics During Exercise streSS

Conditions:   Ischaemic Heart Disease;   Coronary Heart Disease;   Chronic Stable Angina
Interventions:   Drug: Liraglutide;   Other: Placebo
Sponsors:   King's College London;   Guy's and St Thomas' NHS Foundation Trust
Completed - verified May 2015

Is Glucagon-like Peptide-1 Insufficiency a Residual Risk in Coronary Artery Disease?

Condition:   Coronary Artery Disease
Intervention:   Other: Determination of plasma GLP-1 level
Sponsors:   Sapporo Medical University;   Merck Sharp & Dohme Corp.
Recruiting - verified May 2015

Prediction of Recurrent Events With 18F-Fluoride

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:  
Sponsors:   University of Edinburgh;   NHS Lothian;   Oxford University Hospitals NHS Trust;   Central Manchester University Hospitals NHS Foundation Trust;   NHS Grampian;   Wellcome Trust
Not yet recruiting - verified May 2015

AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome)

Conditions:   Turner Syndrome;   Peripheral Angiopathy;   Vascular Malformation;   Lymphedema
Intervention:   Procedure: Echo doppler
Sponsor:   University Hospital, Strasbourg, France
Recruiting - verified May 2015

Eliminate Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Drug: Atorvastatin
Sponsors:   University Health Network, Toronto;   Advanced Medical Research Institute of Canada
Recruiting - verified May 2015

A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol

Condition:   Hyperlipidemia
Interventions:   Drug: Evacetrapib;   Drug: Atorvastatin;   Drug: Ezetimibe;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting - verified May 2015

Care Ecosystem: Navigating Patients and Families Through Stages of Care

Conditions:   Dementia;   Alzheimer Disease;   Dementia, Vascular;   Lewy Body Disease;   Frontotemporal Lobar Degeneration;   Memory Disorders
Intervention:   Behavioral: Navigated Care
Sponsors:   University of California, San Francisco;   University of Nebraska;   Centers for Medicare and Medicaid Services
Recruiting - verified May 2015

Study Of Costs Realized After Percutaneous Coronary intervenTion Employing Same Day Discharge

Condition:   Coronary Artery Disease
Intervention:   Procedure: Same day discharge
Sponsors:   Saint Joseph Mercy Health System;   Michigan Heart;   Blue Cross Blue Shield of Michigan Foundation
Suspended - verified May 2015

CONTRAST (Can cONTrast Injection Better Approximate FFR compAred to Pure reSTing Physiology?)

Condition:   Coronary Artery Disease
Interventions:   Drug: Adenosine;   Drug: Contrast Media;   Drug: Resting conditions
Sponsors:   The University of Texas Health Science Center, Houston;   St. Jude Medical
Completed - verified May 2015

Increasing Cardiac Rehabilitation Participation Among Medicaid Enrollees

Condition:   Coronary Artery Disease
Intervention:   Behavioral: Financial incentives
Sponsors:   University of Vermont;   National Institute of General Medical Sciences (NIGMS)
Recruiting - verified May 2015

Personalized Music Therapy and Agitation in Dementia

Conditions:   Alzheimer's Disease;   Vascular Dementia
Intervention:   Other: Personalized music
Sponsor:   University Health Network, Toronto
Enrolling by invitation - verified May 2015

Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects

Conditions:   Type 2 Diabetes;   Coronary Artery Disease
Intervention:  
Sponsors:   British Cardiac Research Trust;   Royal Free Hospital NHS Foundation Trust;   London North West Healthcare NHS Trust;   Barnet and Chase Farm Hospitals NHS Trust;   Diabetes and Obesity Research Network;   Lund University;   Health Diagnostic Laboratory, Inc.
Recruiting - verified May 2015

Comprehensive Lifestyle Modification for Patients With Hypertension and Metabolic Syndrome: a Multicenter Randomized Controlled Trial

Conditions:   Hypertension;   Metabolic Syndrome
Interventions:   Behavioral: Comprehensive Lifestyle Modification;   Behavioral: DASH
Sponsors:   Universität Duisburg-Essen;   Kliniken Essen-Mitte;   Immanuel Hospital Berlin, Berlin, Germany;   Charité University Medical Center, Berlin, Germany;   University of Witten/Herdecke
Active, not recruiting - verified May 2015

Safety and Performance Study of the Shockwave Lithoplasty System

Condition:   Peripheral Arterial Disease
Intervention:   Device: Shockwave Lithoplasty System
Sponsor:   Shockwave Medical,  Inc.
Completed - verified May 2015

Autologous Bone Marrow Mononuclear Cells in the Combined Treatment of Coronary Heart Disease

Condition:   Ischemic Heart Disease
Intervention:   Procedure: coronary artery bypass grafting with administration of autologous bone marrow stem cells
Sponsor:   St. Petersburg State Pavlov Medical University
Recruiting - verified September 2014

Swedish Drug-elution Trial in Peripheral Arterial Disease

Conditions:   Peripheral Arterial Disease;   Critical Limb Ischemia;   Intermittent Claudication
Interventions:   Procedure: Revascularization with drug-eluting technology;   Procedure: Revascularization without drug-eluting technology;   Device: drug-coated balloons and/or drug-eluting stents
Sponsors:   Sahlgrenska University Hospital, Sweden;   The Swedish Research Council;   Swedish Heart Lung Foundation;   Uppsala University;   The Swedish National Registry for Vascular Surgery
Recruiting - verified May 2015

Cook Micronized Small Intestinal Submucosa (SIS) for Critical Limb Ischemia

Conditions:   Ischemia;   Peripheral Arterial Disease;   Peripheral Vascular Diseases
Intervention:   Device: Micronized Small Intestinal Submucosa (SIS)
Sponsor:   Cook
Recruiting - verified May 2015

Effectiveness of Adventitial Dexamethasone in Peripheral Artery Disease

Condition:   Peripheral Arterial Diseases
Intervention:   Drug: Dexamethasone Sodium Phosphate Injection, USP
Sponsor:   Mercator MedSystems, Inc.
Recruiting - verified May 2015

Dietary Nitrates and Vascular Function in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Dietary Supplement: Sodium Nitrate;   Other: Placebo
Sponsor:   University of Iowa
Recruiting - verified May 2015

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2015

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2015

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia

Condition:   Heterozygous Familial Hypercholesterolemia
Interventions:   Drug: Bococizumab (PF-04950615;RN316);   Other: Placebo
Sponsor:   Pfizer
Active, not recruiting - verified May 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2015

To Study the Safety and Clinical Outcomes of the Absorb Bioresorbable Vascular Scaffold (BVS) System in Patients With de Novo Lesions in Previously Untreated Vessels

Conditions:   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Intervention:   Device: Absorb BVS
Sponsor:   Abbott Vascular
Recruiting - verified May 2015

Safety Trial Of CTX Cells In Patients With Lower Limb Ischaemia

Condition:   Peripheral Arterial Disease
Intervention:   Biological: CTX DP
Sponsor:   ReNeuron Limited
Recruiting - verified May 2015

Vitamin D to Improve Endothelial Function in SLE

Conditions:   Atherosclerosis;   Systemic Lupus Erythematosus
Intervention:   Drug: Cholecalciferol
Sponsor:   Medical University of South Carolina
Completed - verified May 2015

A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ ABSORB CHINA Randomized Controlled Trial (RCT)

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Interventions:   Device: XIENCE V EECSS;   Device: ABSORB BVS System
Sponsor:   Abbott Vascular
Active, not recruiting - verified May 2015

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified May 2015

Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism

Conditions:   Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention:   Drug: L-thyroxine
Sponsor:   Shandong Provincial Hospital
Active, not recruiting - verified May 2015

Portuguese Study on The Evaluation of FFR Guided Treatment of Coronary Disease

Condition:   Coronary Artery Disease
Intervention:   Device: Fractional flow reserve (St. Jude Medical pressure-wire)
Sponsors:   Portuguese Society of Cardiology;   Portuguese Association of Interventional Cardiology;   St. Jude Medical
Completed - verified May 2015

Statins for Pulmonary and Cardiac Complications of Chronic HIV - Coordinating Center

Condition:   HIV Seropositivity
Interventions:   Drug: Placebo;   Drug: Rouvastatin calcium
Sponsor:   University of Pittsburgh
Active, not recruiting - verified September 2014

Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Interventions:   Drug: N-acetyl cysteine;   Drug: Saline
Sponsor:   Suleyman Demirel University
Recruiting - verified October 2014

Prospective Observation Study of Cost Effectiveness of Interventions for Critical Ischemia

Condition:   Critical Limb Ischemia
Interventions:   Procedure: Bypass surgery;   Procedure: Endovascular recanalization
Sponsors:   Sahlgrenska University Hospital, Sweden;   Vastra Gotaland Region
Active, not recruiting - verified May 2015

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified May 2015

Statin Therapy in Young Adult Survivors of Childhood Cancer

Conditions:   Cardiovascular Disease;   Childhood ALL;   Childhood NHL
Interventions:   Drug: Atorvastatin;   Drug: Sugar Pill (Placebo)
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Active, not recruiting - verified May 2015

A Proposed Study of Atherosclerotic Plaques in Leg Arteries

Conditions:   Vascular Disease;   Diabetes
Intervention:  
Sponsor:   Southwest Regional Wound Care Center
Active, not recruiting - verified May 2015

Angina Prevalence and Provider Evaluation of Angina Relief

Condition:   Stable Coronary Artery Disease (CAD).
Intervention:  
Sponsors:   Saint Luke's Health System;   Gilead Sciences
Enrolling by invitation - verified May 2015

Safety and Efficacy of Allogeneic Cells for the Treatment of Intermittent Claudication(IC)

Conditions:   Intermittent Claudication;   Peripheral Artery Disease
Interventions:   Biological: PLX-PAD Low dose;   Biological: PLX-PAD high doses;   Biological: Double Placebo;   Biological: high dose +Placebo
Sponsor:   Pluristem Ltd.
Recruiting - verified May 2015

Efficacy of Physical Exercise in Cardiac Rehabilitation

Conditions:   Coronary Heart Disease;   Heart Failure;   Ischemic Heart Diseases
Interventions:   Other: Supervised physical exercise training x3 weekly for 12 weeks;   Other: Supervised physical exercise training x2 weekly for 8 weeks
Sponsors:   Aarhus University Hospital Skejby;   Institute for Clinical and Experimental Medicine
Completed - verified May 2015

Meta-analyses of Fructose-containing Sugars and Incident Cardiometabolic Disease

Conditions:   Overweight;   Obesity;   Dyslipidemia;   Hyperlipidemia;   Diabetes;   Prediabetes;   Dysglycemia;   Gout;   Hypertension;   Metabolic Syndrome;   Coronary Heart Disease;   Cardiovascular Disease
Intervention:  
Sponsors:   John Sievenpiper;   Calorie Control Council;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research  (CIHR)
Active, not recruiting - verified May 2015

Effect of Bariatric Surgery "Digestive Adaptations III" on Cardiovascular Risk

Conditions:   Diabetes Mellitus;   Metabolic Syndrome;   Obesity;   Atherosclerosis
Intervention:   Procedure: Digestive Adaptations III surgery
Sponsors:   University of Sao Paulo;   Fundação de Amparo à Pesquisa do Estado de São Paulo
Active, not recruiting - verified May 2015

Natural History of Carotid Atherosclerosis

Conditions:   Carotid Artery Disease;   Stroke;   Myocardial Infarction;   Angina Pectoris
Intervention:  
Sponsor:   University of Athens
Recruiting - verified May 2015

Evaluating Cardiovascular Phenotypes Using Induced Pluripotent Stem Cells

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Scripps Translational Science Institute
Enrolling by invitation - verified May 2015

Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina

Conditions:   Chronic Myocardial Ischemia;   Refractory Angina Pectoris;   (Advanced) Coronary Heart Disease
Interventions:   Biological: Auto-CD34+ cells;   Biological: Placebo: Diluent used to suspend Auto-CD34+ cells;   Other: Standard of care
Sponsor:   Baxter Healthcare Corporation
Active, not recruiting - verified May 2015

REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)

Condition:   Diabetes Mellitus, Type 1
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsors:   University of Glasgow;   NHS Greater Glasgow and Clyde;   Juvenile Diabetes Research Foundation;   Imperial College London;   University of Wisconsin, Madison;   University of Dundee;   Merck Serono S.A., Geneva;   Itamar-Medical, Israel;   University of Western Ontario, Canada;   University of Melbourne;   Steno Diabetes Center;   Maastricht University Medical Center
Active, not recruiting - verified May 2015

ESPRIT I: A Clinical Evaluation of the Abbott Vascular ESPRIT BVS (Bioresorbable Vascular Scaffold) System

Conditions:   Atherosclerosis;   Peripheral Vascular Disease;   Claudication
Intervention:   Device: ESPRIT BVS
Sponsor:   Abbott Vascular
Active, not recruiting - verified May 2015

Efficacy of LCQ908 on Cardiovascular Risk

Conditions:   Coronary Artery Disease;   Hypertriglyceridemia
Interventions:   Drug: LCQ908;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Terminated - verified May 2015

Plasmonic Photothermal and Stem Cell Therapy of Atherosclerosis Versus Stenting

Conditions:   Coronary Artery Disease;   Atherosclerosis
Interventions:   Other: Stenting and micro-infusion of NP;   Device: Implantation of everolimus-eluting stent
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation;   Ural Federal University
Terminated - verified May 2015

Vit D and HIV-Cardiovascular Disease in Children and Young Adults Vitamin D and HIV-CVD in Children and Young Adults

Condition:   Vitamin D Deficiency
Intervention:  
Sponsors:   University Hospital Case Medical Center;   Emory-Children's Center
Completed - verified May 2015

Intramyocardial Multiple Precision Injection of Bone Marrow Mononuclear Cells in Myocardial Ischemia

Condition:   Heart Failure
Interventions:   Procedure: NOGA XP Cardiac Navigation System;   Procedure: NOGA XP Cardiac Navigation System
Sponsor:   Federal North-West Medical Research Centre
Recruiting - verified January 2014

Trial of an Internet-based Platform for Managing Chronic Diseases at a Distance

Conditions:   Ischemic Heart Disease;   Heart Failure;   Chronic Kidney Disease;   Diabetes;   Chronic Obstructive Pulmonary Disease
Intervention:   Behavioral: iCDM
Sponsors:   Simon Fraser University;   Canadian Institutes of Health Research  (CIHR);   Michael Smith Foundation for Health Research
Active, not recruiting - verified May 2015

Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)

Condition:   Atherosclerosis
Interventions:   Drug: Canakinumab;   Drug: Placebo
Sponsor:   Novartis Pharmaceuticals
Active, not recruiting - verified May 2015

Randomized Study of Laser and Balloon Angioplasty Versus Balloon Angioplasty to Treat Peripheral In-stent Restenosis

Condition:   Peripheral Arterial Disease
Interventions:   Device: Turbo Elite Laser and Turbo Tandem Laser Guide Catheters;   Procedure: Balloon angioplasty
Sponsor:   Spectranetics Corporation
Completed - verified May 2015

Ranibizumab and the Risk of Arterial Thromboembolic Events

Conditions:   Age-related Macular Degeneration;   Coronary Artery Disease;   Cerebrovascular Disorders
Interventions:   Drug: 0.5 mg of ranibizumab;   Procedure: 0.5 mg of ranibizumab + photodynamic therapy;   Other: Sham injection
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation
Terminated - verified May 2015

Investigate Effect on Mean IMT of Probucol And/or CilosTazol in Patients With Coronary Heart dIsease Taking HMGCoA Reductase Inhibitor Therapy

Condition:   Hyperlipidemias
Interventions:   Drug: HMGCoA reductase inhibitor;   Drug: HMGCoA reductase inhibitor + probucol;   Drug: HMGCA reductase inhibitor + probucol + cilostazol
Sponsors:   Seoul National University Hospital;   Korea Otsuka Pharmaceutical Co.,Ltd.
Active, not recruiting - verified May 2015

Statins in Children With Type 1 Diabetes and Hypercholesterolemia

Conditions:   Diabetes Mellitus, Insulin-Dependent;   Hypercholesterolemia
Interventions:   Drug: Atorvastatin;   Drug: Atorvastatin Placebo
Sponsors:   Nemours Children's Clinic;   Pfizer;   Medtronic;   Quest Diagnostics
Completed - verified May 2015

Mediators of Atherosclerosis in South Asians Living in America

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Coronary Artery Disease;   Coronary Disease
Intervention:  
Sponsors:   University of California, San Francisco;   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified May 2015

Cardiovascular Risk Factors, Lipid Metabolism and Oxidative Stress

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   University of Roma La Sapienza
Recruiting - verified May 2015

Invasive Revascularization or Not in Intermittent Claudication

Condition:   Intermittent Claudication
Interventions:   Procedure: INVASIVE (INV) treatment;   Other: Best medical treatment (BMT)
Sponsors:   Sahlgrenska University Hospital, Sweden;   Göteborg University
Active, not recruiting - verified May 2015

ParisK: Validation of Imaging Techniques

Conditions:   Stroke;   Atherosclerosis
Intervention:   Other: Magnetic Resonance Imaging (MRI), Multidetector Computed Tomography (MDCT), Ultrasonography (US), Transcranial Doppler (TCD)
Sponsor:   Maastricht University Medical Center
Active, not recruiting - verified May 2015

International Survey of Acute Coronary Syndromes in Transitional Countries

Conditions:   Acute Coronary Syndrome;   Unstable Angina Pectoris;   Myocardial Infarction;   Coronary Disease
Intervention:  
Sponsor:   University of Bologna
Recruiting - verified May 2015

The Use of a Community-based Organization to Change Lifestyle Characteristics Related to Non Communicable Diseases

Conditions:   Diabetes;   Hypertension;   Stroke;   Ischemic Heart Disease
Intervention:   Behavioral: lifestyle modification
Sponsor:   University of Kelaniya
Completed - verified May 2015

Detecting Heart Disease Using First Pass Imaging With Gated SPECT Perfusion

Condition:   Ischemic Heart Disease
Intervention:  
Sponsors:   Yale University;   Astellas Pharma US, Inc.
Completed - verified May 2015

FAME II - Fractional Flow Reserve (FFR) Guided Percutaneous Coronary Intervention (PCI) Plus Optimal Medical Treatment (OMT) Verses OMT

Condition:   Coronary Artery Disease
Interventions:   Other: Stenting plus OMT;   Other: Standard of care
Sponsor:   St. Jude Medical
Active, not recruiting - verified May 2015

Improving the Results of Heart Bypass Surgery Using New Approaches to Surgery and Medication

Condition:   Coronary Artery Disease
Interventions:   Procedure: No-touch SVG harvest vs conventional SVG harvest technique;   Dietary Supplement: Fish oil supplementation vs placebo
Sponsors:   Sunnybrook Health Sciences Centre;   Hamilton Health Sciences Corporation
Active, not recruiting - verified November 2011

Fibrinogen and Bleeding After Cardiac Surgery

Conditions:   Complications;   Bleeding;   Coronary Artery Disease
Intervention:   Drug: Fibrinogen
Sponsor:   Sahlgrenska University Hospital, Sweden
Completed - verified May 2015

Safety of Intramuscular Injections (IM) of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia (CLI)

Conditions:   Peripheral Artery Disease;   Peripheral Vascular Disease;   Critical Limb Ischemia
Intervention:   Biological: PLX-PAD
Sponsor:   Pluristem Ltd.
Completed - verified November 2011

Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women

Conditions:   Arterial Stiffening;   Aging;   Menopause
Interventions:   Drug: GnRHant - Ganirelix acetate;   Drug: Transdermal estradiol patch;   Drug: Transdermal placebo patch
Sponsors:   University of Colorado, Denver;   National Institute on Aging (NIA)
Completed - verified May 2015

Insulin Resistance and Atherosclerosis in Women With Lupus

Conditions:   Systemic Lupus Erythematosus;   Insulin Resistance;   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed - verified May 2015

Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques

Conditions:   Atherosclerosis;   Aortic Aneurysm;   Peripheral Vascular Diseases
Intervention:  
Sponsors:   Sheba Medical Center;   University Hospital Goettingen;   Carmel Medical Center;   CVpath Institute, Inc.
Recruiting - verified May 2015

Trial to Enhance Adherence to Multiple Guidelines

Conditions:   Asthma;   Cardiovascular Diseases;   Atherosclerosis;   Diabetes Mellitus;   Heart Diseases;   Hypertension;   Lung Diseases
Intervention:   Other: practice guideline adherence
Sponsors:   University of Medicine and Dentistry of New Jersey;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified May 2015

Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack.

Conditions:   Ischemic Heart Failure;   Ischemic Heart Disease;   Ischemic Cardiomyopathy
Intervention:   Drug: Cellular Therapy (Cultured Autologous Skeletal Myoblast Transplantation)
Sponsor:   Genzyme, a Sanofi Company
Terminated - verified May 2015

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