Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Effects of Lomitapide on Carotid and Aortic Atherosclerosis

Condition:   Homozygous Familial Hypercholesterolemia
Intervention:   Drug: Lomitapide
Sponsor:   Aegerion Pharmaceuticals, Inc.
Not yet recruiting - verified March 2015

Vascular Ultrasound Screening in Patients With Ischemic Cerebrovascular Disease: a Multi-center Registry Study

Condition:   Stroke
Intervention:  
Sponsors:   Xuanwu Hospital, Beijing;   The First Affiliated Hospital of Shanxi Medical University;   Liaocheng Brains Hospital;   Tianjin Huanhu Hospital;   Baotou City Central Hospital;   First Hospital of Jilin University;   First Affiliated Hospital of Harbin Medical University;   First Hospital of China Medical University;   LanZhou University;   First Affiliated Hospital of Xinjiang Medical University;   The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School;   The First Affiliated Hospital of Soochow University;   Anhui Provincial Hospital;   Guangdong Provincial Hospital of Traditional Chinese Medicine;   Zhuhai  People's Hospital;   Fujian Provincial Hospital;   Mianyang Central Hospital;   The Second Affiliated Hospital of Kunming Medical University;   Brains Hospital of Hunan Province;   Henan Provincial Hospital;   Luoyang Central Hospital Affiliated to Zhengzhou University;   National Health and Family Planning Commission Stroke Prevention Engineering Committee
Not yet recruiting - verified March 2015

Epigenetic Reprogramming of Monocytes in Patients With Coronary Atherosclerosis

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Radboud University;   Canisius-Wilhelmina Hospital
Recruiting - verified March 2015

Correlation Between Estimated Glomerular Filtration Rate(eGFR) and Vascular Inflammation Measured by Positron Emission Tomography (PET) With 18F-fluoro-deoxyglucose (FDG)

Condition:   Atherosclerosis
Intervention:   Radiation: 18FDG-PET
Sponsor:   Korea University
Recruiting - verified March 2015

Biomime Stent in All-comers PCI Patients Registry

Condition:   Coronary Artery Disease
Intervention:   Device: percutaneous coronary intervention
Sponsor:   Azienda Ospedaliero Universitaria Maggiore della Carita
Recruiting - verified March 2015

Sequential Coronary CT-angiography and Biomarkers

Conditions:   Coronary Artery Disease;   Atherosclerosis
Interventions:   Radiation: Coronary CT-angiography;   Other: Assesment of biomarkers involved in atherothrombosis
Sponsor:   Maastricht University Medical Center
Recruiting - verified March 2015

An Assessment of the Glider Balloon in Complex Lesions

Condition:   Coronary Artery Disease
Intervention:   Device: PTCA Balloon Angioplasty
Sponsor:   TriReme Medical, LLC
Recruiting - verified March 2015

Pericardial Fat and Inflammation in HIV Patients and Controls

Conditions:   Coronary Artery Disease;   Human Immunodeficiency Virus (HIV)
Intervention:  
Sponsor:   University of Cincinnati
Recruiting - verified January 2015

Clinical Trial to Evaluate Efficacy and Safety of DP-R202 and Anplag in Patients With Artery Occlusive Disease

Condition:   Peripheral Arterial Disease
Interventions:   Drug: DP-R202;   Drug: Anplag tab
Sponsor:   DreamPharma
Completed - verified March 2015

The COPPER-B Trial

Conditions:   Cardiovascular Diseases;   Peripheral Vascular Disease;   Arterial Occlusive Diseases;   Peripheral Arterial Disease;   Critical Limb Ischemia
Intervention:   Other: Paclitaxel administration using the OPC
Sponsors:   Horizons International Peripheral Group;   Advanced Catheter Therapies, Inc.
Recruiting - verified March 2015

Aerobic Exercise and Oxygen Uptake Efficiency Slope in Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Other: Aerobic exercise training
Sponsor:   Hospital TotalCor
Completed - verified March 2015

Comparison of Prevena Negative Pressure Incision Management System vs. Standard Dressing After Vascular Surgery

Conditions:   Peripheral Artery Disease;   Critical Limb Ischemia;   Claudication
Interventions:   Other: standard gauze dressing;   Other: Prevena Incision Management system
Sponsors:   University of Vermont Medical Center;   KCI USA, Inc.;   Maine Medical Center;   Brigham and Women's Hospital;   Beth Israel Deaconess Medical Center
Not yet recruiting - verified March 2015

Outcomes in Femoropopliteal Disease Stratified by Translesional Pressure Gradient

Conditions:   Peripheral Arterial Disease;   Claudication
Intervention:   Procedure: translesional gradient measurement
Sponsor:   North Texas Veterans Healthcare System
Recruiting - verified March 2015

Flaxseed Lignan Supplementation in Elderly Participants With Stage I Hypertension

Condition:   Hypertension
Interventions:   Dietary Supplement: BeneFlax®;   Behavioral: Walking training;   Behavioral: Flexibility training;   Dietary Supplement: Placebo (Whey Protein);   Behavioral: Dash Eating Plan
Sponsor:   University of Saskatchewan
Not yet recruiting - verified February 2015

Contrast Ultrasound Perfusion Imaging in PAD With Sonazoid

Condition:   Peripheral Artery Disease
Interventions:   Procedure: Contrast ultrasound of leg muscle with Sonazoid (Contrast ultrasound microvascular perfusion imaging);   Procedure: Contrast ultrasound of leg muscle with Sonazoid (Stress microvascular ultrasound perfusion imaging);   Drug: Contrast enhanced ultrasound (Sonazoid)
Sponsor:   Oregon Health and Science University
Not yet recruiting - verified March 2015

Reduced Cardiovascular Morbi-mortality by Sildenafil in Patients With Arterial Claudication

Condition:   Peripheral Arterial Disease
Interventions:   Drug: Sildenafil;   Drug: Placebo
Sponsor:   University Hospital, Angers
Not yet recruiting - verified March 2015

Relationship Between Diet, Lifestyle, and the Severity of Coronary Artery Disease

Conditions:   Dietary Habits;   Coronary Artery Disease;   Lifestyle
Intervention:   Behavioral: Survey
Sponsor:   New York University School of Medicine
Recruiting - verified March 2015

DEFINITIVE AR Two Year Follow-up Extension Study

Condition:   Peripheral Arterial Disease
Intervention:  
Sponsor:   Covidien
Recruiting - verified March 2015

Safety and Efficacy of the CRE8 Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Artery Lesions

Condition:   Coronary Artery Disease
Intervention:   Device: CRE8 sirolimus-eluting stent
Sponsor:   CID S.p.A.
Recruiting - verified March 2015

Safety and Efficacy of the CRE8 Stent for the Treatment of De Novo Coronary Artery Lesions

Condition:   Coronary Artery Disease
Interventions:   Device: CRE8 sirolimus-eluting stent;   Device: RESOLUTE zotarolimus-eluting stent
Sponsor:   CID S.p.A.
Recruiting - verified March 2015

Endothelial Function-guided Therapy Compared to Usual Care in Patients With NOCAD

Condition:   Coronary Atherosclerosis
Intervention:  
Sponsor:   Itamar-Medical, Israel
Not yet recruiting - verified March 2015

BIOLUX P-III All-Comers Passeo-18 Lux Registry

Conditions:   Atherosclerosis;   Peripheral Artery Disease
Intervention:   Device: Passeo-18 Lux
Sponsor:   Biotronik AG
Recruiting - verified March 2015

The OCT SORT-OUT VIII Study

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Myocardial Infarction
Interventions:   Device: Everolimus eluting bioresorbable polymer stent;   Device: Biolimus eluting bioresorbable polymer stent
Sponsors:   Aarhus University Hospital Skejby;   Biosensors International;   Boston Scientific Corporation
Recruiting - verified March 2015

Understanding Angioplasty by the Chocolate PTA Balloon Catheter Compared to Conventional PTA Balloons Via OCT Imaging

Condition:   Infrainguinal Peripheral Arterial Disease
Interventions:   Device: Chocolate PTA Balloon Angioplasty;   Device: Standard PTA Balloon Angioplasty
Sponsors:   TriReme Medical, LLC;   University Hospital Case Medical Center
Withdrawn - verified March 2015

A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol

Condition:   Hyperlipidemia
Interventions:   Drug: Evacetrapib;   Drug: Atorvastatin;   Drug: Ezetimibe;   Drug: Placebo
Sponsor:   Eli Lilly and Company
Recruiting - verified March 2015

BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease

Conditions:   Peripheral Artery Disease;   Peripheral Vascular Disease;   Arterial Occlusive Disease
Interventions:   Device: PTA followed by LIFESTREAM™ covered stent;   Device: Device: PTA followed by LIFESTREAM™ covered stent
Sponsor:   C. R. Bard
Recruiting - verified March 2015

Mobile Unit Screening of Pathologies Associated With Chronic Diseases - Feasibility

Conditions:   Chronic Obstructive Pulmonary Disease;   Type II Diabetes;   Atherosclerosis
Interventions:   Other: Patient recruitment;   Procedure: Mobile team exam
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Recruiting - verified March 2015

Care Ecosystem: Navigating Patients and Families Through Stages of Care

Conditions:   Dementia;   Alzheimer Disease;   Dementia, Vascular;   Lewy Body Disease;   Frontotemporal Lobar Degeneration;   Memory Disorders
Intervention:   Behavioral: Navigated Care
Sponsors:   University of California, San Francisco;   University of Nebraska;   Centers for Medicare and Medicaid Services
Recruiting - verified March 2015

FREEDOM: "Pilot Study of the Feasibility and Safety of Resuming Early Walking After Manual Compression in Patients Treated for Peripheral Artery Disease by Endovascular Technique Involving Retrograde Femoral Puncture"

Condition:   Peripheral Arterial Disease
Intervention:   Other: Manual puncture point compression
Sponsor:   Nantes University Hospital
Recruiting - verified March 2015

DOCTOR Compare - A Study in the "DOCTOR" Series (Does Optical Coherence Tomography Optimize Revascularization?"

Conditions:   Coronary Disease;   Myocardial Infarction;   Atherosclerosis
Interventions:   Procedure: Comparison of OCT scans;   Procedure: Comparison of Intra Vascular Optical Coherence Tomography Systems for Assessment of Coronary Tissue, Stents and Scaffolds - DOCTOR Compare
Sponsor:   Aarhus University Hospital Skejby
Completed - verified March 2015

Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study Of PF-06291874 As Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type II
Interventions:   Drug: Placebo;   Drug: PF-06291874;   Drug: PF-06291874;   Drug: PF-06291874;   Drug: PF-06291874
Sponsor:   Pfizer
Recruiting - verified March 2015

The Hellenic Postprandial Lipemia Study (HPLS)

Conditions:   Coronary Heart Disease;   Dyslipidemia
Intervention:  
Sponsor:   Hellenic College of Treatment of Atherosclerosis
Recruiting - verified June 2014

Pharmacokinetics of Everolimus in ABSORB BVS in Patients With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Stenosis
Intervention:   Device: Coronary artery stenting: ABSORB BVS
Sponsor:   Abbott Vascular
Active, not recruiting - verified March 2015

Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Rilapladib (SB659032) in Healthy Volunteers

Condition:   Alzheimer's Disease
Interventions:   Drug: Rilapladib 25 mg;   Drug: Rilapladib 250 mg;   Drug: Itraconazole
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified March 2015

Drug-Coated Chocolate PTA Balloon in Patients With Peripheral Arterial Disease - The ENDURE Trial

Condition:   Peripheral Vascular Disease
Intervention:   Device: Paclitaxel Coated Chocolate Balloon Angioplasty
Sponsor:   TriReme Medical, LLC
Recruiting - verified March 2015

DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury

Condition:   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   University of Edinburgh;   AstraZeneca
Recruiting - verified March 2015

IPHAAB-study Influence of Physical Activity on Atherosclerosis Biomarkers

Condition:   Influence of 8 Months of Increased Physical Activity Workload on Osteoprotegerin and Endocan Levels
Intervention:   Other: Increased sports workload
Sponsors:   Medical University of Vienna;   Austrian Federal Ministry of Defence and Sports
Not yet recruiting - verified March 2015

HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt

Conditions:   Coronary Arteriosclerosis;   Non ST Segment Elevation Acute Coronary Syndrome
Interventions:   Device: OrbusNeich Combo stent™;   Device: Everolimus Eluting Stent (EES)
Sponsors:   OrbusNeich;   OrbusNeich Medical K.K.;   Duke Clinical Research Institute
Recruiting - verified March 2015

Evaluation of a Non-Invasive Electrocardiogram-Assisted Blood Pressure Monitor

Conditions:   Hypertension;   Atrial Fibrillation;   Obesity;   Heart Failure;   Atherosclerosis
Intervention:  
Sponsor:   Health Parametrics Inc.
Active, not recruiting - verified January 2014

Screening for Arteriopathy in General Medicine: a Preliminary Feasibility Study

Condition:   Peripheral Obliterative Arteriopathy
Interventions:   Other: First ultrasound reading;   Other: Second ultrasound interpretation
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Recruiting - verified March 2015

Routine Versus Selective Use of FFR to Guide PCI

Conditions:   Acute Coronary Syndrome;   Coronary Atherosclerosis;   Angina, Unstable
Intervention:   Device: Fractional Flow Reserve (FFR)
Sponsors:   Cardiology Research UBC;   Provincial Health Services Authority
Terminated - verified March 2015

Registry for Estimation of Warfarin and Rivaroxaban in Atrial Fibrillation Patients With Coronary Stent Implantation

Conditions:   Coronary Artery Disease;   Atrial Fibrillation;   Stroke;   Fetal Blood Loss
Intervention:   Drug: Warfarin or Rivaroxaban
Sponsors:   Fujita Health University;   Bayer Yakuhin, Ltd.
Recruiting - verified March 2015

Multiple Electrode Aggregometry & Clopidogrel Resistance

Conditions:   Type 2 Diabetes Mellitus (T2DM);   Coronary Artery Disease (CAD);   Myocardial Infraction
Intervention:  
Sponsor:   Elpen Pharmaceutical Co. Inc.
Completed - verified March 2015

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Recruiting - verified March 2015

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified March 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified March 2015

Influence of FFR on the Clinical Outcome After Percutaneous Coronary Intervention

Condition:   Coronary Disease
Intervention:  
Sponsors:   Inje University;   Seoul National University Hospital;   Keimyung University Dongsan Medical Center;   Ulsan University Hospital;   Hallym University Medical Center;   Kangdong Sacred Heart Hospital;   Busan Veterans General Hospital;   Myongji Hospital;   Chungbuk National University Hospital;   Hanyang University;   Dong-A University Hospital;   Gyeongsang National University Hospital
Recruiting - verified March 2015

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Conditions:   Heart Failure;   Coronary Artery Disease
Interventions:   Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
Sponsors:   Janssen Research & Development, LLC;   Bayer
Recruiting - verified March 2015

Application for Self-Monitoring of Cardiovascular Risk

Condition:   Coronary Artery Disease Which Requires Percutaneous Coronary Intervention(Balloon and/or Stent Treatment).
Intervention:   Device: Self Monitoring Software Application
Sponsor:   Mayo Clinic
Active, not recruiting - verified March 2015

Observational Study to Evaluate PAD Treatment Clinical and Economic Outcomes

Condition:   Peripheral Arterial Occlusive Disease
Intervention:   Other: PAD endovascular treatments
Sponsor:   Cardiovascular Systems Inc
Recruiting - verified March 2015

Effectiveness and Safety Study of Peripheral Balloon Dilatation Catheter in Percutaneous Transluminal Angioplasty(PTA) Procedure

Condition:   Peripheral Arterial Disease
Intervention:   Device: percutaneous transluminal angioplasty balloon catheter
Sponsor:   Acotec Scientific Co., Ltd
Completed - verified November 2012

AcoArt I: Effectiveness and Safety Study of Drug Eluting Balloon(DEB) in Percutaneous Transluminal Angioplasty(PTA) Procedure

Condition:   Peripheral Artery Disease
Interventions:   Device: drug eluting balloon catheter (trade name: Orchid);   Device: common percutaneous transluminal angioplasty balloon catheter (trade name: Admiral)
Sponsor:   Acotec Scientific Co., Ltd
Active, not recruiting - verified December 2014

PROMISE Substudy to Assess For Effective Dose of Radiation (PROMISE-SAFER) Specific Aim 3b

Conditions:   Chest Pain;   Coronary Artery Disease;   Angina
Intervention:  
Sponsors:   Kaiser Permanente;   Columbia University
Active, not recruiting - verified March 2015

Angiogenesis and Fibrosis in Myocardial Infarction

Conditions:   Myocardial Infarction;   Fibrosis;   Neovascularization, Pathologic
Interventions:   Procedure: Cardiac MRI scan;   Radiation: CT-PET scan;   Radiation: CT-coronary angiogram
Sponsor:   University of Edinburgh
Recruiting - verified March 2015

Angiogenesis and Fibrosis in Aortic Stenosis

Conditions:   Aortic Stenosis;   Fibrosis;   Neovascularization, Pathologic
Interventions:   Procedure: Cardiac MRI scan;   Radiation: CT-PET scan;   Procedure: Echocardiogram;   Radiation: CT-coronary angiogram scan;   Procedure: Aortic Valve Replacement
Sponsor:   University of Edinburgh
Recruiting - verified March 2015

Effect of Isoflurane on Tissue Doppler Imaging of Mitral Annulus During Cardiac Surgery

Conditions:   Valvular Heart Disease;   Ischemic Heart Disease
Intervention:   Drug: Isoflurane
Sponsor:   Konkuk University Medical Center
Completed - verified March 2015

The Treatment of Coronary Artery Lesions Using the PRO-Kinetic Energy Cobalt-Chromium, Bare-Metal Stent

Condition:   Coronary Artery Disease
Intervention:   Device: PRO-Kinetic Energy Stent
Sponsor:   Biotronik AG
Terminated - verified March 2015

Lipoprotein Apheresis in Refractory Angina Study

Conditions:   Refractory Angina;   Raised Lipoprotein(a)>50mg/dL or >500mg/L
Interventions:   Other: Lipoprotein Apheresis;   Other: Sham Apheresis
Sponsors:   Imperial College London;   National Institute for Health Research, United Kingdom
Active, not recruiting - verified February 2013

Mindful Hearts Study

Conditions:   Cardiovascular Disease;   Psychological Stress;   Stroke;   Coronary Artery Disease
Interventions:   Behavioral: Mindfulness Based Stress Reduction;   Behavioral: Health Education Program
Sponsor:   Department of Veterans Affairs
Recruiting - verified March 2015

Clinical Evaluation of the CADence Device in Detection of Coronary Artery Diseases

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   AUM Cardiovascular, Inc.
Recruiting - verified March 2015

Complete vs Culprit-only Revascularization to Treat Multi-vessel Disease After Primary PCI for STEMI

Conditions:   Acute Myocardial Infarction;   Coronary Artery Disease;   Percutaneous Coronary Intervention
Intervention:   Procedure: Complete Revascularization Strategy
Sponsor:   Population Health Research Institute
Recruiting - verified March 2015

Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasis

Conditions:   Psoriasis;   Vascular Inflammation;   Coronary Atherosclerosis
Interventions:   Biological: Adalimumab;   Other: Placebo
Sponsors:   Innovaderm Research Inc.;   Abbott;   Montreal Heart Institute
Active, not recruiting - verified September 2014

Single Long vs Two Short Overlapping Bioabsorbable Polymer DES

Condition:   Coronary Artery Disease
Intervention:   Device: implantation of a bioabsorbable polymer DES
Sponsor:   Azienda Ospedaliero Universitaria Maggiore della Carita
Recruiting - verified March 2015

Optimal Physiologic Intravascular Ultrasound Imaging Criteria After Drug Eluting Stent Implantation

Condition:   Coronary Disease
Intervention:  
Sponsors:   Inje University;   Seoul National University Hospital
Completed - verified March 2015

HeartTrends Heart Rate Variability (HRV) Algorithm for the Diagnosis of Myocardial Ischemia

Condition:   Ischemic Heart Disease
Intervention:  
Sponsor:   Sheba Medical Center
Completed - verified March 2015

Depression Care for Hospitalized Coronary Heart Disease Patients: Prospective Cohort Study

Conditions:   Coronary Heart Disease;   Depression
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   University Hospital Muenster
Active, not recruiting - verified March 2015

Antiplatelet Therapy Guided by Thrombelastography in Patients With Acute Coronary Syndromes (TEGCOR Study)

Conditions:   Thrombosis;   Coronary Artery Disease
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel
Sponsor:   Indiana University
Recruiting - verified March 2015

Remote Ischemic Preconditioning Prior to Vascular Surgery

Conditions:   Peripheral Arterial Disease;   Vascular Surgery
Interventions:   Procedure: Preconditioning;   Procedure: Control
Sponsor:   Department of Veterans Affairs
Recruiting - verified March 2015

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia

Conditions:   Arterial Occlusive Disease;   Ulcers;   Ischemia;   Peripheral Vascular Disease
Interventions:   Genetic: NL003;   Genetic: NL003;   Genetic: NL003;   Other: Normal Saline
Sponsors:   Beijing Northland Biotech. Co., Ltd.;   ViroMed Co., Ltd. dba VM BioPharma
Completed - verified March 2015

Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen.

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Losmapimod;   Drug: Placebo
Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   Technology Strategy Board;   GlaxoSmithKline;   Royal Brompton & Harefield NHS Foundation Trust;   University of Cambridge
Completed - verified March 2015

BIOFLOW-III All-comers Orsiro Safety and Performance Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:  
Sponsor:   Biotronik AG
Active, not recruiting - verified March 2015

Study to Improve Long Term Vein Graft Patency After Coronary Bypass Surgery by Using a Novel Endoscopic Harvesting Technique

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Baylor Research Institute;   Maquet Cardiovascular
Completed - verified March 2015

The Nordic-Baltic Bifurcation Study IV

Condition:   Coronary Artery Disease
Interventions:   Procedure: Implantation of coronary stent in bifurcation lesion;   Procedure: Implantation of coronary stent in bifurcation lesion
Sponsors:   Niels Ramsing Holm;   Johnson & Johnson
Active, not recruiting - verified March 2015

Coronary Hybrid Revascularisation Study

Condition:   Significant Coronary Artery Disease
Intervention:   Procedure: Combined CABG and PCI
Sponsor:   Aarhus University Hospital Skejby
Recruiting - verified March 2015

VH-IVUS Plaque Composition Analysis By Fractional Flow Reserve

Condition:   Coronary Disease
Intervention:  
Sponsors:   Inje University;   Seoul National University Hospital
Completed - verified March 2015

Diagnostic Performances of Computed TomographIc Coronary Angiography and Intravascular Ultrasound

Condition:   Diagnosis Coronary Artery Disease
Intervention:   Procedure: diagnostic procedures CCTA, CAG, IVUS and FFR
Sponsors:   Seoul National University Hospital;   Inje University
Completed - verified March 2015

Ticagrelor and Aspirin for the Prevention of Cardiovascular Events After Coronary Artery Bypass Surgery

Condition:   Coronary Artery Disease
Interventions:   Drug: ticagrelor;   Drug: Placebo
Sponsors:   Cardiology Research UBC;   University of British Columbia
Completed - verified March 2013

Impact of Coronary Artery Bypass Graft (CABG) Surgery on Skeletal Muscle Mass and Insulin Sensitivity, Followed by Exercise Intervention

Condition:   Coronary Artery Disease
Intervention:   Other: exercise training
Sponsor:   Hasselt University
Completed - verified March 2015

Validation/Evaluation of Multimodal Imaging Combining 3D Ultrasound and Stress Myocardial Scintigraphy in the Diagnosis of Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Coronary Disease
Interventions:   Procedure: Stress ultrasound;   Procedure: Scintigraphy;   Procedure: Coronary angiography
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Withdrawn - verified March 2015

Bone Marrow Aspirate Concentrate (BMAC) for Treatment of Critical Limb Ischemia (CLI)

Condition:   Critical Limb Ischemia
Interventions:   Device: BMAC injection;   Device: Placebo injection
Sponsor:   Harvest Technologies
Active, not recruiting - verified June 2014

Omega 3 Fatty Acid Efficiency for Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting

Conditions:   Ischemic Heart Disease;   Atrial Fibrillation
Interventions:   Drug: Omega-3 fish oil emulsion (Omegaven);   Drug: Intralipid
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Terminated - verified March 2015

Rubidium-82 Position Emission Computed Tomography (PET) Versus Gated, Rest / Stress Technetium 99-m SPECT

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Heart Disease
Interventions:   Other: SPECT imaging;   Other: PET imaging
Sponsors:   Hartford Hospital;   Bracco Diagnostics, Inc
Completed - verified July 2012

ACELLDream for Adipose CELL Derived Regenerative Endothelial Angiogenic Medicine

Conditions:   Peripheral Vascular Diseases;   Cardiovascular Diseases
Intervention:   Other: Expanded autologous ASCs
Sponsors:   University Hospital, Toulouse;   French Blood Establishment (Midi-Pyrénées);   Clinical Research Center, Toulouse;   France: Centre National de la Recherche Scientifique
Completed - verified March 2015

Data Aquisition for Optimization of Coronary Artery Disease Algorithm

Condition:   Coronary Artery Disease
Intervention:   Device: ProtoCAD
Sponsors:   Coloplast A/S;   Rigshospitalet, Denmark
Completed - verified March 2015

Drug-Eluting Balloon Catheters and the Treatment of Peripheral Arterial Occlusive Disease

Conditions:   Peripheral Arterial Disease;   Stenotic Femoro-popliteal Arteries;   Occluded Femoro-popliteal Arteries;   Atherosclerosis
Intervention:   Device: Paclitaxel-coated balloon catheter angioplasty
Sponsor:   Bayer
Completed - verified March 2015

Stress Management and Biomarkers of Risk in Cardiac Rehabilitation

Condition:   Coronary Heart Disease
Interventions:   Behavioral: SMT-enhanced Cardiac Rehabilitation;   Behavioral: Standard Cardiac Rehabilitation
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified March 2015

Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)

Condition:   Atherosclerosis
Interventions:   Drug: Ezetrol (Ezetimibe);   Drug: Vytorin (Ezetimibe + Simvastatin)
Sponsor:   Korea University
Withdrawn - verified June 2010

Comparison of the SUpera® PERipheral System in the Superficial Femoral Artery

Condition:   Peripheral Vascular Disease
Intervention:   Device: SUPERA® Nitinol Stent System
Sponsors:   IDev Technologies, Inc.;   Harvard Clinical Research Institute
Completed - verified March 2015

The Nordic Bifurcation Study III

Condition:   Coronary Artery Disease
Intervention:   Procedure: Percutaneous coronary intervention (PCI)
Sponsors:   Niels Ramsing Holm;   Johnson & Johnson
Active, not recruiting - verified March 2015

INDICOR The Paclitaxel-Eluting PTCA-Balloon Catheter in Combination With a Cobalt-Chromium Stent

Condition:   Coronary Heart Diseases
Interventions:   Device: Drug Eluting Balloon SeQuent Please;   Device: Drug Eluting Balloon SeQuent Please
Sponsors:   Ralf Degenhardt, PhD;   B. Braun Melsungen AG
Active, not recruiting - verified March 2015

A Phase 1 Safety Study of the Intravenous Administration of Thymosin Beta in Healthy Volunteers

Conditions:   Myocardial Infarction;   Myocardial Ischemia
Interventions:   Drug: thymosin beta 4;   Other: Placebo
Sponsor:   RegeneRx Biopharmaceuticals, Inc.
Completed - verified March 2015

Hepatitis C Treatment and Atherosclerosis

Conditions:   Chronic Hepatitis C;   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified March 2015

Carotid Intima-media Thickness in Japan Statin Treatment Against Recurrent Stroke(J-STARS Echo)

Condition:   Ischemic Stroke
Intervention:   Drug: Statin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University;   National Cerebral and Cardiovascular Center
Active, not recruiting - verified March 2015

Assessing Myocardial Blood Flow and Blood Flow Reserve by Transoesophageal Echocardiography (TEE)

Condition:   Coronary Artery Disease
Interventions:   Drug: SonoVue;   Drug: Optison
Sponsor:   University Hospital, Basel, Switzerland
Withdrawn - verified March 2015

SB-480848 In Subjects With Coronary Heart Disease

Condition:   Atherosclerosis
Intervention:   Drug: SB-480848
Sponsor:   GlaxoSmithKline
Completed - verified March 2015

Testosterone and Myocardial Perfusion in CHD

Condition:   Coronary Heart Disease
Intervention:   Drug: Testosterone undecanoate
Sponsors:   Imperial College London;   Organon
Completed - verified October 2005

Japan Statin Treatment Against Recurrent Stroke (J-STARS)

Condition:   Ischemic Stroke
Intervention:   Drug: Pravastatin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University
Active, not recruiting - verified March 2015

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