Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Serial Phlebotomy in Voluntary Blood Donors

Condition:   Atherosclerosis
Intervention:   Other: Phlebotomy
Sponsors:   New York University School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI);   National Center for Research Resources (NCRR)
Completed - verified May 2016

Arsenic, Disordered Glucose Homeostasis and Atherosclerosis

Conditions:   Atherosclerosis;   Type 2 Diabetes (T2D)
Intervention:  
Sponsor:   New York University School of Medicine
Recruiting - verified April 2016

Timing of Complete Revascularization for Multivessel Coronary Artery Disease in STEMI

Condition:   Myocardial Infarction
Interventions:   Procedure: PCI;   Procedure: dobutamine stress echocardiography
Sponsors:   Clinical Hospital Center Zemun;   Institute for cardiovascular diseases Vojvodina, Novi Sad, Serbia;   Military Medical Academy, Belgrade, Serbia;   Clinical Center Kragujevac, Kragujevac, Serbia
Recruiting - verified April 2016

Post-operative Treatment of Diabetic Peripheral Arterial Disease Guided by Platelet Reactivity Unit

Condition:   Peripheral Artery Disease
Interventions:   Other: platelet (P2Y12) reaction units;   Drug: ticagrelor;   Drug: Comparator
Sponsor:   Chang Gung Memorial Hospital
Enrolling by invitation - verified May 2016

Norwegian Carotid Plaque Study

Conditions:   Ischemic Stroke;   Carotid Artery Disease;   Embolic Stroke
Intervention:  
Sponsors:   Haukeland University Hospital;   University of Bergen
Not yet recruiting - verified April 2016

CONTECI Program: A New Way to Control Peripheral Arterial Disease Using New Technologies

Conditions:   Peripheral Arterial Disease;   Personal Satisfaction;   Telemedicine
Intervention:   Other: Selfmanage with the help of telemedicine program
Sponsor:   Consorci Sanitari del Maresme
Completed - verified May 2016

Safety and Preliminary Efficacy of Adipose Derived Stem Cells and Low Frequency Ultrasound in Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Procedure: Lipoaspiration;   Other: Intravenous injection of Adipose Derived Stem Cells;   Other: Intra-adventitia (proximal to the lesion) injection of Adipose Derived Stem Cells;   Other: Intra-muscular injection of Adipose Derived Stem Cells;   Other: Low Frequency Ultrasound (LoFU) Delivery
Sponsors:   Arkansas Heart Hospital;   National Institutes of Health (NIH);   SonaCare Medical
Recruiting - verified April 2016

Claudication, Systematic Evaluation of Limp on Treadmill

Condition:   Peripheral Artery Disease
Intervention:   Behavioral: Biomechanic parameters in PAD patients
Sponsor:   University Hospital, Angers
Not yet recruiting - verified April 2016

RISCAID Study: Remote ISchemic Conditioning for Angiopathy In Diabetes

Condition:   Peripheral Arterial Disease
Interventions:   Device: AutoRIC: Remote Ischemic Conditioning;   Device: AutoRIC: Sham device treatment
Sponsors:   Steno Diabetes Center;   Aarhus University Hospital;   German Diabetes Center
Not yet recruiting - verified April 2016

The Norwegian Stroke in the Young Study II

Condition:   Ischemic Stroke at a Young Age
Intervention:  
Sponsors:   Haukeland University Hospital;   Helsinki University Central Hospital
Recruiting - verified May 2016

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk

Conditions:   Hypercholesterolemia;   Atherosclerotic Cardiovascular Diseases
Interventions:   Drug: ETC-1002;   Drug: Placebo
Sponsor:   Esperion Therapeutics
Recruiting - verified May 2016

DEB ( Drug Eluting Balloon) in Crural Arteries and Critical Limb Ischemia

Condition:   Peripheral Vascular Diseases
Interventions:   Device: DEB;   Device: POBA
Sponsor:   Skane University Hospital
Recruiting - verified April 2016

A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)

Condition:   Homozygous Familial Hypercholesterolemia
Intervention:   Genetic: AAV directed hLDLR gene therapy
Sponsor:   University of Pennsylvania
Recruiting - verified May 2016

Safety and Feasibility of SurModics SurVeil (TM) Drug Coated Balloon

Conditions:   Peripheral Arterial Disease;   Peripheral Vascular Diseases
Interventions:   Device: SurVeil Drug Coated Balloon;   Procedure: Angioplasty
Sponsor:   SurModics, Inc.
Recruiting - verified May 2016

Effect of Sarpogrelate, a Serotonin Receptor Antagonist, on Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Drug: Sarpogrelate;   Drug: Aspirin
Sponsor:   Seoul National University Bundang Hospital
Completed - verified May 2016

Post-revascularization Rehabilitation to Improve Function in Veterans With PAD

Conditions:   Peripheral Arterial Disease;   Intermittent Claudication
Interventions:   Other: Exercise training;   Other: NMES
Sponsor:   VA Office of Research and Development
Recruiting - verified April 2016

Telmisartan Plus Exercise to Improve Functioning in Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Behavioral: Supervised Treadmill Exercise Therapy;   Drug: Telmisartan;   Other: "No exercise" control group;   Drug: Placebo
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical Atherosclerosis

Condition:   Atherosclerosis
Interventions:   Drug: Rosuvastatin;   Drug: Placebo
Sponsor:   AstraZeneca
Recruiting - verified April 2016

Low InTensity Exercise Intervention in PAD

Condition:   Peripheral Artery Disease
Interventions:   Behavioral: Exercise;   Other: Attention control
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Micro-embolic Signals Detection With Transcranial HOLter in Acute Ischemic STroke

Condition:   Stroke
Intervention:   Device: Transcranial-holter monitoring
Sponsor:   University Hospital, Bordeaux
Recruiting - verified March 2016

Tack Optimized Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries

Condition:   Peripheral Artery Disease
Intervention:   Device: Tack Endovascular System
Sponsor:   Intact Vascular
Recruiting - verified May 2016

PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis (Volunteer - BioD and Safety Study)

Condition:   Atherosclerosis
Intervention:   Drug: Cu[64]-25%CANF-Comb
Sponsor:   Washington University School of Medicine
Completed - verified April 2016

Clinical and Laboratory Biomarkers in Patients With Atherothrombotic Stroke

Conditions:   Carotid Artery Diseases;   Stroke
Intervention:   Other: Biomarkers serum level measurement
Sponsor:   St. Petersburg State Pavlov Medical University
Recruiting - verified May 2016

Patient Centered Home Exercise Program for Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Intervention:   Behavioral: Home-based exercise intervention
Sponsors:   Northwestern University;   Patient-Centered Outcomes Research Institute
Recruiting - verified May 2016

PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis

Condition:   Carotid Atherosclerosis
Intervention:   Device: Cu[64]-25%-CANF-Comb PET-MR
Sponsor:   Washington University School of Medicine
Recruiting - verified April 2016

Women's Health Initiative Strong and Healthy Study

Conditions:   Myocardial Infarction;   Stroke;   Cardiovascular Mortality;   Hip Fractures;   Falls;   Mortality;   Venous Thromboembolic Event;   Peripheral Artery Disease
Intervention:   Behavioral: Physical Activity
Sponsors:   Fred Hutchinson Cancer Research Center;   University of California, San Diego;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified April 2016

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Harvard Clinical Research Institute;   Medstar Research Institute
Active, not recruiting - verified February 2016

Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase II

Condition:   Acute Coronary Artery Syndrome
Interventions:   Procedure: Percutaneous coronary intervention;   Procedure: Intravascular ultrasound with virtual histology;   Drug: Atorvastatin or other equivalent dose statin;   Device: LDL-apheresis
Sponsor:   VA Office of Research and Development
Recruiting - verified May 2016

"In Vivo" Comparison in Human Carotid Atherosclerosis: Plaque Neovascularization

Conditions:   Carotid Artery Disease;   Plaque Neovascularization
Interventions:   Other: Contrast enhanced ultrasound of the carotid plaque;   Other: Dynamic contrast-enhanced carotid plaque MRI
Sponsor:   Ospedale San Giovanni Bellinzona
Completed - verified April 2016

Effect of Cilostazol on Coronary Artery Stenosis and Plaque Characteristics in Patients With T2DM

Condition:   Coronary Artery Disease
Interventions:   Drug: Cilostazol;   Drug: Aspirin
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified May 2016

Efficacy and Safety of Intramuscular PDA-002 in Subjects Who Have Diabetic Foot Ulcer With and Without Peripheral Arterial Disease

Conditions:   Peripheral Arterial Disease;   Diabetic Foot
Interventions:   Biological: 3 x 10^6 cells;   Biological: 10 x 10^6 cells;   Biological: 30 x 10^6 cells;   Other: Placebo
Sponsor:   Celgene Corporation
Recruiting - verified April 2016

A Registration Study for Dyslipidemia

Condition:   Atherosclerotic Vascular Diseases
Intervention:  
Sponsor:   National Taiwan University Hospital
Recruiting - verified April 2016

Effect of Bydureon on Carotid Atherosclerosis Progression in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes
Interventions:   Drug: Bydureon;   Drug: placebo
Sponsor:   Phoenix VA Health Care System
Recruiting - verified May 2016

The Effects of Fish Oil Supplements During Supervised Exercise Therapy in Patients With Intermittent Claudication

Condition:   Intermittent Claudication
Intervention:   Drug: Omega-3 fatty acids
Sponsor:   Medical Center Alkmaar
Terminated - verified September 2015

Platelet Activity in Vascular Surgery and Cardiovascular Events

Conditions:   Cardiovascular Disease;   Peripheral Artery Disease;   Critical Limb Ischemia
Intervention:  
Sponsors:   New York University School of Medicine;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

The Lipid-Rich Plaque Study

Conditions:   Coronary Artery Disease;   Atherosclerosis
Intervention:  
Sponsors:   InfraReDx;   Medstar Research Institute
Active, not recruiting - verified April 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2016

DPP4inhibitors in Type 1 Diabetes

Conditions:   Type 1 Diabetes;   Hypoglycaemia
Intervention:   Drug: Saxagliptin
Sponsor:   University of Dundee
Completed - verified May 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified May 2016

A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease

Condition:   Cardiovascular Disease, Coronary Heart Disease, Dyslipidemia, Peripheral Arterial Disease (PAD)
Interventions:   Other: Background care;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified May 2016

COroNary CT Angiography Evaluation For Clinical Outcomes: An InteRnational Multicenter Registry (CONFIRM)

Conditions:   Atherosclerosis;   Coronary Artery Disease;   Cardiovascular Disease
Intervention:  
Sponsor:   Weill Medical College of Cornell University
Enrolling by invitation - verified April 2016

Ultrasound and Other Images of Artery Blockages

Condition:   Atherosclerosis
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Terminated - verified April 2016

Treadmill Exercise and GM-CSF Study to Improving Functioning in Peripheral Artery Disease (PAD)

Condition:   Peripheral Arterial Disease
Interventions:   Behavioral: Supervised Treadmill Exercise Therapy;   Other: Health education sessions (Control);   Drug: granulocyte macrophage colony stimulating factor (GM-CSF)
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

A Multiple Ascending Dose Study of RO4905417 in Healthy Volunteers and Patients With Peripheral Arterial Disease (PAD).

Condition:   Peripheral Arterial Disease (PAD)
Interventions:   Drug: RO4905417;   Drug: RO4905417;   Drug: RO4905417;   Drug: placebo;   Drug: placebo;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified May 2016

Insulin Resistance and Atherosclerosis in Women With Lupus

Conditions:   Systemic Lupus Erythematosus;   Insulin Resistance;   Atherosclerosis
Intervention:  
Sponsor:   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed - verified April 2016

RESPECT PFO Clinical Trial

Condition:   Cryptogenic Stroke
Interventions:   Device: AMPLATZER PFO Occluder;   Other: Standard of Care - Medical Management
Sponsor:   St. Jude Medical
Active, not recruiting - verified May 2016

ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

Conditions:   Cardiovascular Disease;   Coronary Artery Calcification
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified November 2015

Carotid Intima-media Thickness in Japan Statin Treatment Against Recurrent Stroke(J-STARS Echo)

Condition:   Ischemic Stroke
Intervention:   Drug: Statin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University;   National Cerebral and Cardiovascular Center
Completed - verified April 2016

Japan Statin Treatment Against Recurrent Stroke (J-STARS)

Condition:   Ischemic Stroke
Intervention:   Drug: Pravastatin
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Ministry of Health, Labour and Welfare, Japan;   Hiroshima University
Completed - verified March 2015

Epidemiology of Atherosclerosis

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Heart Diseases;   Coronary Arteriosclerosis
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2000

Jackson Heart Study (JHS) of Cardiovascular Diseases in African Americans

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Atherosclerosis;   Coronary Disease;   Hypertension;   Cerebrovascular Disorders
Intervention:  
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Institute on Minority Health and Health Disparities (NIMHD)
Active, not recruiting - verified April 2016