Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Whole Milk Compared With Skimmed Milk and Effect on Lipids

Condition:   Atherosclerosis
Intervention:   Other: Milk type
Sponsor:   University of Copenhagen
Completed - verified February 2017

Pathogenic Mechanisms of Cancer and Cardiovascular Diseases

Conditions:   Pathogenesis;   Cardiovascular Diseases;   Cancer
Intervention:   Diagnostic Test: micro RNA
Sponsors:   Sakakibara Heart Institute;   Japanese Foundation for Cancer Research
Recruiting - verified February 2017

Short-term Perfusion Angiography Pilot Study (SPA)

Condition:   Peripheral Arterial Disease
Intervention:  
Sponsor:   Volcano Corporation
Recruiting - verified November 2016

Improve PAD PERformance With METformin

Condition:   Peripheral Artery Disease
Interventions:   Drug: Metformin;   Drug: Placebo
Sponsor:   Northwestern University
Not yet recruiting - verified February 2017

Platelet Acetyl Coenzyme A Carboxylase Phosphorylation in Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome;   Coronary Thrombosis
Intervention:   Diagnostic Test: Platelet Acetyl Coenzyme A Carboxylase analysis in CAD
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Completed - verified February 2017

BIOLUX P-III BENELUX All-Comers Registry

Condition:   Peripheral Arterial Disease
Intervention:   Device: Passeo-18 Lux DCB
Sponsor:   Biotronik AG
Recruiting - verified February 2017

BIOLUX P-III SPAIN All-Comers Registry

Condition:   Peripheral Arterial Disease
Intervention:   Device: Passeo-18 Lux DCB
Sponsor:   Biotronik AG
Not yet recruiting - verified February 2017

Comparing TR Band to Statseal in Conjunction With TR Band

Conditions:   Arterial Occlusion;   Angina Pectoris;   Cardiovascular Diseases;   Atherosclerosis;   Hematoma;   Anticoagulant-Induced Bleeding;   Coronary Artery Disease
Interventions:   Device: StatSeal;   Device: TR Band
Sponsor:   VA Long Beach Healthcare System
Not yet recruiting - verified February 2017

Multiple Ascending Doses of MEDI6012 in Subjects With Stable Atherosclerotic Cardiovascular Disease

Conditions:   Atherosclerosis;   Cardiovascular Disease
Interventions:   Biological: MEDI6012;   Biological: Placebo
Sponsor:   MedImmune LLC
Recruiting - verified February 2017

Machine Learning for Handheld Vascular Studies

Conditions:   Atherosclerosis;   Wounds and Injuries
Interventions:   Device: Non-invasive vascular testing;   Device: machine-learning algorithm
Sponsor:   Duke University
Recruiting - verified February 2017

Shockwave Medical Peripheral Lithoplasty System Study for PAD (Disrupt PAD III)

Condition:   Peripheral Arterial Disease
Interventions:   Device: Shockwave Lithoplasty® Peripheral Lithoplasty System;   Drug: Medtronic IN.PACT (DCB)
Sponsor:   Shockwave Medical, Inc.
Not yet recruiting - verified February 2017

Trial Comparing ELUVIA Versus Bare Metal Stent in Treatment of Superficial Femoral and/or Proximal Popliteal Artery

Conditions:   Arterial Occlusive Diseases;   Atherosclerosis;   Vascular Diseases;   Arteriosclerosis
Intervention:   Device: Peripheral stenting
Sponsor:   Boston Scientific Corporation
Recruiting - verified February 2017

Safety and Feasibility of the Shockwave Lithoplasty® System for the Treatment of Peripheral Vascular Stenosis

Condition:   Peripheral Arterial Disease
Intervention:   Device: Shockwave Lithoplasty® System
Sponsor:   Shockwave Medical, Inc.
Recruiting - verified February 2017

VascTrac Peripheral Arterial Disease (PAD) Study

Conditions:   Peripheral Artery Disease;   Intermittent Claudication
Intervention:   Behavioral: Physical activity levels
Sponsors:   Palo Alto Veterans Institute for Research;   Cook;   Gore;   Abbott
Not yet recruiting - verified February 2017

Humacyte's HAV for Femoro-Popliteal Bypass in Patients With PAD

Condition:   Peripheral Artery Disease
Intervention:   Biological: Human Acellular Vessel (HAV)
Sponsors:   Humacyte, Inc.;   Atlantic Research Group
Recruiting - verified February 2017

Efficacy, Safety, and Tolerability of Oral Ubrogepant in the Acute Treatment of Migraine

Condition:   Migraine, With or Without Aura
Interventions:   Drug: Ubrogepant;   Drug: Placebo-matching Ubrogepant
Sponsor:   Allergan
Recruiting - verified February 2017

Body Fat Mass Association With Clinical Metabolic Profiles, Markers of Inflammation and Adipocytokines

Condition:   Overweight and Obesity
Intervention:  
Sponsor:   Tungs’ Taichung Metroharbour Hospital
Completed - verified February 2017

The DESappear Study: Drug Eluting Scaffold

Condition:   Peripheral Vascular Disease
Intervention:   Device: Akesys Prava Scaffold
Sponsors:   Elixir Medical Corporation;   Syntactx;   Massachusetts General Hospital
Recruiting - verified February 2017

Peripheral Registry of Endovascular Clinical Outcomes "The PRIME Registry"

Conditions:   Peripheral Arterial Disease;   Peripheral Vascular Disease;   Critical Limb Ischemia
Intervention:  
Sponsors:   Metro Health, Michigan;   C. R. Bard;   Terumo Medical Corporation;   AccessClosure, Inc.;   Cardiovascular Systems Inc;   Boston Scientific Corporation;   Spectranetics Corporation;   Medtronic - MITG
Recruiting - verified April 2016

Cocoa to Improve Walking Performance in Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Cocoa;   Drug: Placebo
Sponsors:   Northwestern University;   National Institute on Aging (NIA)
Recruiting - verified February 2017

Trhombus Aspiration in Hyperglycemic ST-elevation myocardiAl InfarcTIon

Condition:   Hyperglycemia
Intervention:   Device: percutaneous coronary intervention
Sponsor:   Second University of Naples
Completed - verified February 2017

Serum Level of Myokines and Protein Energy Wasting, Inflammation and Atherosclerosis in Hemodialysis Patients

Condition:   Protein-energy; Imbalance
Intervention:  
Sponsor:   Tungs’ Taichung Metroharbour Hospital
Completed - verified February 2017

A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)

Condition:   Homozygous Familial Hypercholesterolemia
Intervention:   Biological: AAV directed hLDLR gene therapy
Sponsor:   University of Pennsylvania
Recruiting - verified January 2017

Compare I Pilot Study for the Treatment of Subjects With Symptomatic Femoropopliteal Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Device: Ranger Drug Eluting Balloon;   Device: In Pact Drug Eluting Balloon
Sponsor:   University of Leipzig
Recruiting - verified February 2017

Exercise Training in Individuals With Peripheral Arterial Disease

Conditions:   Peripheral Arterial Disease;   Intermittent Claudication
Intervention:   Other: Exercise training
Sponsor:   University Medical Centre Ljubljana
Recruiting - verified November 2016

Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen

Condition:   Aging-related Inflammation in HIV-infected Patients
Interventions:   Drug: Raltegravir;   Drug: PI-based regimen;   Drug: Atorvastatin
Sponsor:   Fundacio Lluita Contra la SIDA
Active, not recruiting - verified February 2017

Angioplasty + SBCV vs. Angioplasty Alone for Femoropopliteal Artery Stenosis

Condition:   Peripheral Arterial Disease
Interventions:   Other: SBCV;   Other: Saline
Sponsors:   Symic Vascular;   Symic Biomedical, Inc.
Active, not recruiting - verified February 2017

iPhone App Compared to Standard RR-measurement

Conditions:   Hypertension;   Blood Pressure
Interventions:   Device: cuff device (Omron HBP-1300-E Pro);   Device: iPhone 4s
Sponsors:   Jens Eckstein;   Preventicus GmbH
Completed - verified February 2017

A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical Atherosclerosis

Condition:   Atherosclerosis
Interventions:   Drug: Rosuvastatin;   Drug: Placebo
Sponsor:   AstraZeneca
Active, not recruiting - verified February 2017

Low InTensity Exercise Intervention in PAD

Condition:   Peripheral Artery Disease
Interventions:   Behavioral: Exercise;   Other: Attention control
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified February 2017

Patient Centered Home Exercise Program for Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Intervention:   Behavioral: Home-based exercise intervention
Sponsors:   Northwestern University;   Patient-Centered Outcomes Research Institute
Recruiting - verified February 2017

Effect of Bydureon on Carotid Atherosclerosis Progression in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes
Interventions:   Drug: Bydureon;   Drug: placebo
Sponsor:   Phoenix VA Health Care System
Recruiting - verified February 2017

Non-invasive Computer-Aided Phenotyping of Vasculopathy

Conditions:   Carotid Atherosclerosis;   Peripheral Arterial Disease
Intervention:  
Sponsor:   Elucid Bioimaging Inc.
Recruiting - verified February 2017

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Terminated - verified February 2017

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Terminated - verified February 2017

Correlation Between Coronary and Carotid Atherosclerotic Disease and Links With Clinical Outcomes

Condition:   Vascular Disease
Intervention:  
Sponsor:   Montreal Heart Institute
Completed - verified February 2017

Zilver® PTX® V Clinical Study

Condition:   Peripheral Arterial Disease
Intervention:   Device: Zilver® PTX® Drug-Eluting Peripheral Stent
Sponsor:   Cook
Active, not recruiting - verified February 2017

Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia

Condition:   Homozygous Familial Hypercholesterolemia
Interventions:   Genetic: Gene analysis;   Other: Historical data of lipid-lowering drug administration;   Other: Historical data of plasma lipids, xanthoma changes
Sponsor:   Central South University
Completed - verified February 2017

Evaluation of the Safety and Efficacy of a Vascular Prosthesis as an Above-Knee Bypass Graft in Patients With PAD

Conditions:   Peripheral Arterial Disease;   Peripheral Vascular Disease
Intervention:   Device: HAVG graft implantation
Sponsors:   Humacyte, Inc.;   FGK Clinical Research Sp. zo.o.;   FGK Clinical Research GmbH
Active, not recruiting - verified February 2017

The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI)

Conditions:   Metabolic Disease;   Cardiovascular Disease;   Inflammation
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified January 24, 2017

Treadmill Exercise and GM-CSF Study to Improving Functioning in Peripheral Artery Disease (PAD)

Condition:   Peripheral Arterial Disease
Interventions:   Behavioral: Supervised Treadmill Exercise Therapy;   Other: Health education sessions (Control);   Drug: granulocyte macrophage colony stimulating factor (GM-CSF)
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified February 2017

Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study)

Conditions:   Atherosclerosis;   Cardiovascular Disease;   Vascular Diseases
Intervention:  
Sponsor:   National Institute on Aging (NIA)
Active, not recruiting - verified January 26, 2017