Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Drug: Metformin;   Dietary Supplement: Agave inulin;   Other: Placebo of agave inulin;   Other: Metformin placebo
Sponsor:   Centro Universitario de Ciencias de la Salud, Mexico
Completed - verified May 2016

Stress-MRI Assessment After Right Coronary Artery CTO Recanalization

Conditions:   Ischemic Heart Disease;   Coronary Atherosclerosis;   Coronary Artery Disease;   Coronary Artery Stenosis
Interventions:   Procedure: CTO coronary angioplasty;   Drug: Optimal medicamentous treatment;   Procedure: Stress-MRI
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Completed - verified May 2016

Evaluation of WIRION™ EPS in Lower Extremities Arteries

Condition:   Peripheral Arterial Disease (PAD)
Intervention:   Device: WIRION
Sponsor:   Gardia Medical
Not yet recruiting - verified May 2016

Prospective Study Evaluating the Interest of Long-term Cardiac Recording in Cerebral Infarction

Condition:   Neuropathology
Intervention:   Device: Uses of SpiderFlash monitor
Sponsor:   Groupe Hospitalier Paris Saint Joseph
Recruiting - verified May 2016

A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes

Condition:   Ischemic Stroke
Intervention:   Drug: TF0023
Sponsor:   Techfields Inc
Not yet recruiting - verified May 2016

Cilostazol Following Peripheral Endovascular Procedures

Condition:   Peripheral Arterial Disease
Interventions:   Drug: Cilostazol;   Drug: Aspirin
Sponsors:   Attikon Hospital;   University Hospital of Patras
Not yet recruiting - verified May 2016

The Application of Digital Infrared Thermal Imaging in Peripheral Artery Disease of the Lower Extremities

Conditions:   Peripheral Artery Disease;   Diabetes Mellitus
Intervention:   Procedure: Percutaneous balloon angioplasty
Sponsor:   National Taiwan University Hospital
Recruiting - verified May 2016

A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)

Condition:   Homozygous Familial Hypercholesterolemia
Intervention:   Genetic: AAV directed hLDLR gene therapy
Sponsor:   University of Pennsylvania
Recruiting - verified May 2016

Text Messaging to Promote Walking Among Latino Adults at Risk for Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Other: Text Messages;   Other: Phone Calls;   Other: Handout
Sponsors:   University of Kansas Medical Center;   National Institute on Aging (NIA)
Recruiting - verified May 2016

Performing a Low-dose, Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA

Conditions:   Stroke;   Ischemic Attack, Transient
Interventions:   Other: Routine Imaging Assessment;   Device: LDWBA first (CT scan)
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified May 2016

The Cholesterol Lowering Effects of Strawberry

Conditions:   Hypercholesterolemia;   Glycemic Response
Interventions:   Dietary Supplement: Active Treatment Beverage;   Dietary Supplement: Placebo Treatment Beverage
Sponsor:   Institute for Food Safety and Health, United States
Recruiting - verified May 2016

Exercise and Weight Loss to Improve Mobility Function in Veterans With PAD

Condition:   Peripheral Arterial Disease
Interventions:   Other: Exercise;   Other: Weight Loss
Sponsor:   VA Office of Research and Development
Recruiting - verified May 2016

Non-invasive Liver Screening for Risk Assessment for Coronary Heart Disease

Conditions:   Coronary Disease;   Non-alcoholic Fatty Liver Disease;   Elasticity Imaging Techniques
Interventions:   Device: Fibro Scan;   Genetic: PNPLA3
Sponsors:   University of Leipzig;   Universitätsklinikum Leipzig
Recruiting - verified May 2016

Angioplasty + SBCV vs. Angioplasty Alone for Femoropopliteal Artery Stenosis

Condition:   Peripheral Arterial Disease
Interventions:   Other: SBCV;   Other: Saline
Sponsors:   Symic Vascular;   Symic Biomedical, Inc.
Recruiting - verified May 2016

The PaWS (Pedometer and Walking Study)

Condition:   Intermittent Claudication
Intervention:   Other: Pedometer
Sponsors:   University Health Network, Toronto;   St. Michael
Recruiting - verified May 2016

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified May 2016

PeRiodontal Treatment to Eliminate Minority InEquality and Rural Disparities in Stroke

Conditions:   Periodontal Disease;   Stroke;   TIA
Interventions:   Procedure: Intensive dental treatment;   Procedure: Standard dental treatment;   Drug: Arestin
Sponsors:   University of South Carolina;   University of North Carolina, Chapel Hill
Recruiting - verified May 2016

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Recruiting - verified May 2016

Clear-Road Trial, Investigating the Efficacy of the RoadSaver Stent

Condition:   Peripheral Arterial Disease
Intervention:   Device: RoadSaver stent
Sponsor:   Flanders Medical Research Program
Active, not recruiting - verified February 2016

BIOLUX P-III All-Comers Passeo-18 Lux Registry

Conditions:   Atherosclerosis;   Peripheral Artery Disease
Intervention:   Device: Passeo-18 Lux
Sponsor:   Biotronik AG
Recruiting - verified May 2016

Biomarker Signature of Stroke Aetiology Study: The BIOSIGNAL-Study

Condition:   Stroke, Acute
Intervention:  
Sponsors:   University of Zurich;   Swiss National Science Foundation
Recruiting - verified May 2016

A Real World, Observational Registry of Chronic Wounds and Ulcers

Conditions:   Diabetic Foot;   Varicose Ulcer;   Pressure Ulcer;   Surgical Wound Dehiscence;   Vasculitis;   Skin Ulcer;   Leg Ulcer;   Wounds and Injuries;   Pyoderma;   Peripheral Arterial Disease;   Diabetic Neuropathies;   Lymphedema;   Venous Insufficiency;   Diabetes Complications;   Amputation Stump
Intervention:   Other: Usual care
Sponsor:   U.S. Wound Registry
Recruiting - verified May 2016

PLATINUM Diversity

Conditions:   Atherosclerosis;   Coronary Artery Disease
Intervention:   Device: Percutaneous coronary intervention (Promus PREMIER)
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified May 2016

Physician-Initiated Trial Investigating the BeGraft Peripheral Stent Graft System

Condition:   Peripheral Vascular Disease
Intervention:   Device: BeGraft Peripheral Stent Graft System
Sponsor:   Flanders Medical Research Program
Completed - verified February 2016

Comparison of Agent™ and SeQuent® Please Paclitaxel Coated Balloon Catheters in Coronary In-stent Restenosis (AGENT-ISR)

Conditions:   Coronary Artery Disease;   Coronary Restenosis;   Coronary Atherosclerosis;   Coronary Arteriosclerosis
Interventions:   Device: Agent Paclitaxel-coated balloon;   Device: SeQuent® Please Paclitaxel-coated Balloon
Sponsor:   Hemoteq AG
Active, not recruiting - verified May 2016

The Impact of Ezetimibe on Biochemical Markers of Cardiovascular Risk in Kidney Transplant Patients

Conditions:   Dyslipidemia;   Transplants
Intervention:   Drug: Ezetimibe
Sponsor:   University Medical Centre Ljubljana
Completed - verified May 2016

Use and Safety of the LUTONIX® Drug Coated Balloon Catheter in Arteries of the Lower Extremity

Condition:   Peripheral Artery Disease
Intervention:   Device: Lutonix Drug Coated Balloon Catheter
Sponsor:   C. R. Bard
Active, not recruiting - verified May 2016

Screening for Arteriopathy in General Medicine: a Preliminary Feasibility Study

Condition:   Peripheral Obliterative Arteriopathy
Interventions:   Other: First ultrasound reading;   Other: Second ultrasound interpretation
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Recruiting - verified May 2016

Acute Cardiovascular Responses and Chronic Adaptations of Strength Exercise in Intermittent Claudication Patients

Conditions:   Peripheral Artery Disease;   Intermittent Claudication
Interventions:   Behavioral: Resistance training;   Behavioral: Control
Sponsors:   University of Pernambuco;   Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco;   Conselho Nacional de Desenvolvimento Científico e Tecnológico
Completed - verified May 2016

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2016

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Recruiting - verified May 2016

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia

Condition:   Heterozygous Familial Hypercholesterolemia
Interventions:   Drug: Bococizumab (PF-04950615;RN316);   Other: Placebo
Sponsor:   Pfizer
Completed - verified May 2016

RNA Cloning and Visualization in Human Atherosclerosis

Condition:   Atherosclerosis
Intervention:  
Sponsor:   University of Kentucky
Active, not recruiting - verified May 2016

Home Exercise Intervention in Persons With Multiple Sclerosis

Condition:   Multiple Sclerosis
Intervention:   Other: home-based exercise training condition
Sponsor:   University of Illinois at Chicago
Active, not recruiting - verified May 2016

The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI)

Conditions:   Metabolic Disease;   Cardiovascular Disease;   Inflammation
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

The Arterial Measurement of the Blood Flow Volume After Iloprost Stimulation

Conditions:   Diabetes;   Arteriosclerosis;   Peripheral Arterial Occlusive Disease;   Neuropathy
Intervention:   Drug: Ilomedin
Sponsors:   Prim PD Dr Afshin Assadian;   Wilhelminenspital Vienna
Recruiting - verified May 2016

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

Condition:   Peripheral Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   AstraZeneca
Active, not recruiting - verified May 2016

Safety and Efficacy of Allogeneic Cells for the Treatment of Intermittent Claudication(IC)

Conditions:   Intermittent Claudication;   Peripheral Artery Disease
Interventions:   Biological: PLX-PAD Low dose;   Biological: PLX-PAD high doses;   Biological: Double Placebo;   Biological: high dose +Placebo
Sponsor:   Pluristem Ltd.
Recruiting - verified February 2016

PacLitaxel Eluting Balloon Application In Sfa In Stent Restenosis

Condition:   Peripheral Arterial Disease
Intervention:   Procedure: PacLitaxel Eluting Balloon Application
Sponsor:   Nantes University Hospital
Completed - verified May 2016

The Effect of Gastric Bypass Surgery on Diabetes

Condition:   Type II Diabetes
Intervention:  
Sponsors:   University of Oulu;   Oulu University Hospital
Recruiting - verified May 2016

Anti-inflammatory Agents and Cholesterol Metabolism

Condition:   Osteoarthritis
Intervention:  
Sponsor:   Winthrop University Hospital
Recruiting - verified May 2016

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

Conditions:   Asthma;   Atherosclerosis;   Metabolic Syndrome;   Insulin Resistance;   Cancer
Intervention:  
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Enrolling by invitation - verified November 2015

Individualized Comprehensive Atherosclerosis Risk-reduction Evaluation Program

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Piedmont Healthcare;   Abbott
Active, not recruiting - verified May 2016

Trial of Drug Eluting Stent Versus Bare Metal Stent to Treat Coronary Artery Stenosis

Conditions:   Coronary Atherosclerosis;   Angina Pectoris;   Myocardial Infarction
Interventions:   Device: Percutaneous coronary intervention (PCI);   Device: Percutaneous coronary intervention (PCI)
Sponsors:   University of Tromso;   The Research Council of Norway;   The Royal Norwegian Ministry of Health;   Norwegian Council on Cardiovascular diseases
Active, not recruiting - verified May 2016

Better Adherence to Therapeutic Lifestyle Change Efforts Trial

Condition:   Cardiovascular Disease
Intervention:   Behavioral: CIMT results
Sponsors:   Walter Reed National Military Medical Center;   Henry M. Jackson Foundation for the Advancement of Military Medicine
Completed - verified May 2016

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection

Condition:   Job's Syndrome
Intervention:  
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Albert Einstein College of Medicine of Yeshiva University
Recruiting - verified May 2016