Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Effect of Cilostazol on Carotid Atherosclerosis Estimated by 3D Ultrasound in Patients With Type 2 Diabetes

Conditions:   Type 2 Diabetes Mellitus;   Carotid Atherosclerosis
Interventions:   Drug: Cilostazol;   Drug: Aspirin
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified August 2017

Normal Parameters of Cranial Vessels Using Cranial Vascular Duplex Among Egyptian Population

Conditions:   Atherosclerosis;   Atheroma of Cerebral Arteries;   Atheroma; Carotid Artery;   Atheroma; Cerebral
Intervention:   Radiation: vascular duplex ultrasound imaging
Sponsor:   Assiut University
Not yet recruiting - verified August 2017

Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke

Condition:   Stroke
Interventions:   Drug: Alprostadil;   Drug: Normal saline
Sponsor:   First Hospital of Jilin University
Not yet recruiting - verified August 2017

18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability

Conditions:   Myocardial Infarction;   Myocardial Ischemia;   Atherosclerosis;   Coronary Artery Disease;   Coronary Stenosis;   Heart Attack;   Multi Vessel Coronary Artery Disease
Interventions:   Diagnostic Test: PET-MRI;   Procedure: Optical Coherence Tomography
Sponsors:   Maastricht University Medical Center;   VieCuri Medical Centre;   Stichting de Weijerhorst
Not yet recruiting - verified August 2017

Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies

Conditions:   Chronic Obstructive Pulmonary Disease;   Emphysema
Interventions:   Biological: Belimumab;   Drug: Placebo
Sponsors:   University of Alabama at Birmingham;   GlaxoSmithKline
Not yet recruiting - verified August 2017

Cardiac Rehabilitation Program in Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Other: Cardiac Rehabilitation Program;   Other: Conventional Therapy
Sponsor:   University of Kansas Medical Center
Recruiting - verified August 2017

Extracellular RNAs in Relation to Cardiometabolic Risk

Conditions:   Subclinical Atherosclerotic Cardiovascular Disease;   Blood Pressure;   Obesity
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified August 1, 2017

Pilot Study of Pre-Ischemic Conditioning for Intracranial Atherosclerosis

Condition:   Intracranial Atherosclerosis
Interventions:   Device: Doctormate;   Other: Usual Care
Sponsors:   Medical University of South Carolina;   University of Southern California;   University of California, Los Angeles;   Augusta University
Recruiting - verified June 2017

Predictors of AAA Expansion and/or Rupture

Condition:   Abdominal Aortic Aneurysm (AAA)
Interventions:   Device: Assess AAA rupture risk by PET-CTA scans;   Diagnostic Test: 18F-fludeoxyglucose (FDG);   Diagnostic Test: 11C-PBR28
Sponsor:   Washington University School of Medicine
Recruiting - verified August 2017

Antiplatelet Effects of Evolocumab in Patients With Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Intervention:   Drug: Evolocumab
Sponsor:   Inova Health Care Services
Recruiting - verified August 2017

Effects of Platelet Rich Fibrin (PRF) in Treatment of Non-healing Sternum Wound After Open-heart Surgery

Condition:   Sternal Wound Repair
Interventions:   Biological: PRF;   Biological: placebo group
Sponsor:   SCARM Institute, Tabriz, Iran
Not yet recruiting - verified May 2017

Bleeding Risk Evaluation in Haemophilia Patients Under Antiplatelet Therapies

Condition:   Hemophilia
Intervention:   Other: Non interventional study
Sponsor:   Nantes University Hospital
Recruiting - verified August 2017

The Effect of GRAVITY on Physiological Measurements During Invasive Coronary Angiography and Intervention

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Basildon and Thurrock University Hospitals NHS Foundation Trust;   Anglia Ruskin University
Recruiting - verified August 2017

N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes

Conditions:   Diabetes Mellitus;   Critical Limb Ischemia;   Lower Limb Amputation Knee;   Peripheral Arterial Disease
Interventions:   Drug: Active Arm N-acetyl cysteine (NAC);   Drug: Placebo Arm
Sponsor:   Washington University School of Medicine
Recruiting - verified August 2017

RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty

Conditions:   Peripheral Artery Disease;   Atherosclerosis;   Artery Diseases, Peripheral;   Plaque, Atherosclerotic;   Occlusive Arterial Disease
Interventions:   Device: RANGER™ Paclitaxel Coated Balloon;   Drug: Paclitaxel;   Procedure: Standard Balloon Angiplasty
Sponsor:   Boston Scientific Corporation
Recruiting - verified August 2017

Multiple Ascending Doses of MEDI6012 in Subjects With Stable Atherosclerotic Cardiovascular Disease

Conditions:   Atherosclerosis;   Cardiovascular Disease
Interventions:   Biological: MEDI6012;   Biological: Placebo
Sponsor:   MedImmune LLC
Recruiting - verified August 2017

Paclitaxel-coated Peripheral Stents Used in the Treatment of Femoropopliteal Stenoses

Condition:   Peripheral Arterial Disease (PAD)
Interventions:   Device: Zilver® Paclitaxel-Eluting Peripheral Stent;   Device: Zilver® Paclitaxel-Eluting Peripheral Stent with slower-dissolving polymer-free paclitaxel coating;   Device: Zilver® Paclitaxel-Eluting Peripheral Stent with higher-dose polymer-free paclitaxel coating
Sponsor:   Cook Group Incorporated
Recruiting - verified May 2017

Carotid Atherosclerosis : Innovative Imaging Biomarkers. Study Case-control

Condition:   Carotid Stenosis
Intervention:   Device: HITS quantification, Ultrasound examinations, High Resolution MRI
Sponsors:   Hospices Civils de Lyon;   Fondation de France;   Bracco Imaging S.p.A.
Recruiting - verified August 2017

Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)

Conditions:   Peripheral Artery Disease;   Vascular Disease;   Critical Limb Ischemia
Intervention:   Device: Injection of cBMA aspirate into the index leg
Sponsors:   Michael Murphy;   Zimmer Biomet
Active, not recruiting - verified August 2017

Comparison of the Vasomotor Function and Myocardial Flow in Patients Treated With Bioresorbable and Metallic Stents at 1 Year

Condition:   Stable Angina
Interventions:   Device: Bioresorbable vascular scaffold;   Device: Everolimus-eluting stent
Sponsors:   Institut d'Investigació Biomèdica de Bellvitge;   Fundació La Marató de TV3
Active, not recruiting - verified August 2017

A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation

Conditions:   Ischemia;   Peripheral Arterial Disease;   Peripheral Vascular Disease;   Vascular Disease;   Arterial Occlusive Disease;   Arteriosclerosis;   Atherosclerosis;   Cardiovascular Disease;   Pathologic Processes;   Orthopedic Procedures;   Amputation
Intervention:   Biological: Allogeneic bone marrow derived mesenchymal stem cells
Sponsor:   Indiana University
Recruiting - verified August 2017

Effect of Dapagliflozin on Vascular Functions in Patients With Type 2 Diabetes Compared to Gliclazide

Condition:   Diabetes
Interventions:   Drug: Dapagliflozin;   Drug: Gliclazide
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified August 2017

A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical Atherosclerosis

Condition:   Atherosclerosis
Interventions:   Drug: Rosuvastatin;   Drug: Placebo
Sponsor:   AstraZeneca
Active, not recruiting - verified August 2017

Efficacy of Subintimal vs Intraluminal Approach for Atherosclerotic Chronic Occlusive Femoropopliteal Arterial Disease

Conditions:   Peripheral Arterial Disease;   Atherosclerosis
Interventions:   Procedure: Intentional intraluminal approach;   Procedure: Intentional subintimal approach
Sponsor:   Korea University Guro Hospital
Recruiting - verified August 2017

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified August 2017

Lowering Blood Pressure in Primary Care in Vienna

Condition:   Hypertension
Intervention:   Drug: Olmesartan medoxomil, amlodipine, hydrochlorothiazide
Sponsors:   Wilhelminenspital Vienna;   Association for the Promotion of Research in Atherosclerosis, Thrombosis and Vascular Biology;   Ludwig Boltzmann Foundation for Cardiovascular Research
Completed - verified August 2017

BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease

Conditions:   Peripheral Artery Disease;   Peripheral Vascular Disease;   Arterial Occlusive Disease
Interventions:   Procedure: Percutaneous transluminal angioplasty (PTA);   Device: LIFESTREAM™ covered stent
Sponsor:   C. R. Bard
Active, not recruiting - verified August 2017

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   Cleveland Clinic Coordinating Center for Clinical Research (C5R);   Quintiles, Inc.
Active, not recruiting - verified August 2017

Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis

Conditions:   Aortocoronary Saphenous Vein Bypass Graft Atherosclerosis;   Intermediate Saphenous Vein Graft Lesions
Intervention:   Drug: extended-release niacin (Niaspan)
Sponsors:   North Texas Veterans Healthcare System;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 2017

Data Registry Following Patients Using Supera Stent in the Femoral Arteries

Conditions:   Peripheral Artery Disease;   Femoropopliteal Artery Stenosis;   Peripheral Vascular Disease
Intervention:   Device: SUPERA Interwoven self-expanding nitinol stent
Sponsor:   Abbott Vascular
Terminated - verified August 2017

Local Paclitaxel Delivery for SFA Disease

Conditions:   Atherosclerosis;   Angioplasty;   Peripheral Arterial Disease
Intervention:   Drug: Paclitaxel
Sponsor:   University of Oklahoma
Completed - verified August 2017