Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Study to Evaluate the Effect of Nicotinamide Riboside on Immunity

Conditions:   Atherosclerosis;   Diabetes;   Coronary Artery Disease
Interventions:   Dietary Supplement: Nicotinamide riboside (NR);   Other: Placebo
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 2016

Endothelial Dysfunction and Subclinical Atheromatosis in Chronic HCV Infection. Response to DAA Agents.

Conditions:   Hepatitis C;   Cardiovascular Diseases
Intervention:   Other: Cardiovascular risk in HCV patients
Sponsors:   Instituto de Investigación Marqués de Valdecilla;   Ministerio de Economía y Competitividad, Spain
Recruiting - verified June 2016

Triglyceride-rich Lipoprotein and Development of Dementia

Condition:   Dementia
Intervention:  
Sponsor:   National Taiwan University Hospital
Recruiting - verified June 2016

Folinic Acid: Supplementation and Therapy

Conditions:   HIV Infection;   HCV Coinfection
Interventions:   Drug: Folinic Acid;   Drug: Placebo
Sponsors:   Hospital de Clinicas de Porto Alegre;   Universidade Federal de Santa Maria
Completed - verified June 2016

Lutonix or Inpact for tHE tReatment Of fEmeropopliteal Stenosis - DCB

Condition:   Peripheral Arterial Disease
Interventions:   Device: Lutonix;   Device: IN.PACT
Sponsor:   Advocate Health Care
Recruiting - verified June 2016

Gonadal Hormone, Gonadotropin and Cardiovascular Events

Conditions:   Aging;   Menopause
Intervention:  
Sponsor:   Shandong Provincial Hospital
Recruiting - verified June 2016

Clinical Significance of Antiphospholipid Antibodies in Healthy Subjects

Condition:   Antiphospholipid Antibodies
Intervention:   Biological: blood sample
Sponsor:   Centre Hospitalier Universitaire, Amiens
Completed - verified June 2016

Assessing the Feasibility of BGC101 in the Treatment of PAD & CLI

Conditions:   Critical Limb Ischemia;   Peripheral Arterial Disease;   Peripheral Vascular Disease
Interventions:   Other: BGC101 (autologous EnEPC preparation);   Other: Control medium
Sponsors:   BioGenCell Ltd.;   Laniado Hospital
Not yet recruiting - verified June 2016

Clinical Trial Investigating the Efficacy of the Supera Peripheral Stent System for the Treatment of the Common Femoral Artery

Condition:   Peripheral Arterial Disease
Intervention:   Device: Supera Peripheral Stent System
Sponsor:   ID3 Medical
Recruiting - verified June 2016

Tack Optimized Drug Coated Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries

Condition:   Peripheral Arterial Disease
Intervention:   Device: Tack Endovascular System
Sponsor:   Intact Vascular
Recruiting - verified June 2016

Body Fat Mass Association With Clinical Metabolic Profiles, Markers of Inflammation and Adipocytokines

Condition:   Overweight and Obesity
Intervention:  
Sponsor:   Tungs’ Taichung Metroharbour Hospital
Enrolling by invitation - verified June 2016

Stellarex Vascular E-Registry

Condition:   Peripheral Arterial Disease
Intervention:   Device: Percutaneous Transluminal Angioplasty
Sponsor:   Spectranetics Corporation
Recruiting - verified June 2016

Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging

Conditions:   Peripheral Artery Disease;   Vascular Disease;   Critical Limb Ischemia
Interventions:   Drug: Dexamethasone infusion;   Device: Drug coated balloon
Sponsors:   University of California, San Francisco;   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 2016

Safety and Effectiveness of Jetstream Atherectomy System (J-SUPREME)

Condition:   Peripheral Arterial Disease
Intervention:   Device: Jetstream Atherectomy System
Sponsor:   Boston Scientific Corporation
Recruiting - verified June 2016

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Condition:   Hypercholesteremia
Interventions:   Drug: Gemcabene 300 mg;   Drug: Gemcabene 600 mg;   Drug: Gemcabene 900 mg
Sponsor:   Gemphire Therapeutics, Inc.
Recruiting - verified June 2016

Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term

Condition:   Atherosclerotic Cardiovascular Disease
Intervention:   Drug: aspirin
Sponsors:   Duke University;   Patient-Centered Outcomes Research Institute;   Mytrus;   Chicago Area Patient Centered Outcomes Research Network;   Greater Plains Collaborative Clinical Data Research Network;   Mid-South Clinical Data Research Network;   Research Action for Health Network;   Patient-Centered Scalable National Network for Effectiveness Research;   PaTH Clinical Data Research Network;   New York City Clinical Data Research Network;   Health eHeart Patient Powered Network
Enrolling by invitation - verified January 2016

99mTc-rhAnnexin V-128 Imaging for Carotid Atherosclerosis

Condition:   Carotid Artery Plaque
Intervention:   Radiation: 99mTc-rhAnnexin V-128
Sponsor:   Advanced Accelerator Applications
Recruiting - verified June 2016

A Comparator Trial on the Relative Efficacy of Two Triglyceride Forms of Fish Oil

Condition:   Healthy Volunteers
Interventions:   Dietary Supplement: Fish Oil;   Dietary Supplement: Fish Oil
Sponsors:   Nordic Pharma, USA;   Nutrasource Diagnostics Inc.
Active, not recruiting - verified June 2016

Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen

Condition:   Aging-related Inflammation in HIV-infected Patients
Interventions:   Drug: Raltegravir;   Drug: PI-based regimen;   Drug: Atorvastatin
Sponsor:   Fundacio Lluita Contra la SIDA
Recruiting - verified June 2016

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

Condition:   Peripheral Artery Disease
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban-Placebo
Sponsors:   Bayer;   Janssen Research & Development, LLC;   Colorado Prevention Center
Recruiting - verified June 2016

Safety and Efficacy of Autologous Concentrated Bone Marrow Aspirate for Critical Limb Ischemia - Continued Access

Conditions:   Peripheral Arterial Disease;   Peripheral Vascular Diseases;   Critical Limb Ischemia
Intervention:   Device: Bone marrow concentration device
Sponsor:   Biomet, Inc.
Available - verified June 2016

Evaluation of Short Versus Long Duration Dual Antiplatelet Therapy in Patients Undergoing Lower Extremity Endovascular Revascularization

Conditions:   Peripheral Arterial Disease;   Endovascular Procedures
Interventions:   Drug: Aspirin;   Drug: Clopidogrel
Sponsor:   University Hospital Case Medical Center
Not yet recruiting - verified June 2016

Effects of Remote Ischemic Preconditioning on Restenosis Post Lower Limb Revascularization Angioplasty

Condition:   Peripheral Vascular Diseases
Intervention:   Other: Remote Ischemic Preconditioning
Sponsors:   National University of Ireland, Galway, Ireland;   University College Hospital Galway
Recruiting - verified June 2016

Effects of Remote Ischemic Preconditioning on Moderate PVD Patients A Pilot Randomized Control Trial

Condition:   Peripheral Arterial Diseases
Interventions:   Other: Remote Ischemic Preconditioning;   Other: Supervised Exercise;   Other: Standard Care
Sponsors:   National University of Ireland, Galway, Ireland;   University College Hospital Galway
Recruiting - verified June 2016

Telomeres and Arterial Aging

Condition:   Atherosclerotic Disease
Intervention:  
Sponsors:   Central Hospital, Nancy, France;   National Research Agency, France;   Institut National de la Santé Et de la Recherche Médicale, France;   Assistance Publique Hopitaux De Marseille;   University of Lorraine
Recruiting - verified June 2016

Non-invasive Computer-Aided Phenotyping of Vasculopathy

Conditions:   Carotid Atherosclerosis;   Peripheral Arterial Disease
Intervention:  
Sponsor:   Elucid Bioimaging Inc.
Recruiting - verified June 2016

DLBS1033 Treatment in Diabetic With Peripheral Arterial Disease

Conditions:   Diabetes;   Peripheral Arterial Disease
Interventions:   Drug: DLBS1033;   Drug: Placebo
Sponsor:   Dexa Medica Group
Recruiting - verified June 2016

EARly Prevention of aTHeroma Progression

Condition:   Coronary Arteriosclerosis
Interventions:   Behavioral: Standard Therapy;   Drug: Rosuvastatin
Sponsors:   CHEOL WHAN LEE, M.D., Ph.D;   CardioVascular Research Foundation, Korea
Recruiting - verified June 2016

Outcomes of Femoro-popliteal Disease After Stent Deployment Under Intravascular Ultrasound Guidance

Condition:   Peripheral Arterial Disease
Intervention:  
Sponsor:   Texas Tech University Health Sciences Center
Active, not recruiting - verified June 2016

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events

Condition:   Hyperlipidemia
Interventions:   Drug: Bococizumab (PF-04950615; RN316);   Other: Placebo
Sponsor:   Pfizer
Active, not recruiting - verified June 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified June 2016

Optical Imaging Measurement of Intravascular Solution Efficacy Trial

Condition:   Peripheral Artery Disease
Intervention:   Procedure: iOCT
Sponsor:   University Hospital Case Medical Center
Completed - verified June 2016

IN.PACT Global Clinical Study

Condition:   Peripheral Arterial Disease
Intervention:   Device: IN.PACT Admiral™ Drug Eluting Balloon
Sponsor:   Medtronic Endovascular
Active, not recruiting - verified June 2016

Remote Ischemic Preconditioning Prior to Vascular Surgery

Conditions:   Peripheral Arterial Disease;   Vascular Surgery
Interventions:   Procedure: Preconditioning;   Procedure: Control
Sponsor:   VA Office of Research and Development
Active, not recruiting - verified June 2016

Optimized Supervised Education Program for Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Intervention:   Other: Patient education
Sponsor:   Rennes University Hospital
Terminated - verified June 2016

Safety and Efficacy Study of Autologous Concentrated Bone Marrow Aspirate (cBMA) for Critical Limb Ischemia (CLI)

Conditions:   Critical Limb Ischemia;   Peripheral Arterial Disease;   Peripheral Vascular Disease
Interventions:   Device: Bone marrow concentration device;   Procedure: Placebo procedure (sham)
Sponsor:   Biomet Biologics, LLC
Active, not recruiting - verified June 2016

Cardiovascular Disease Study

Condition:   Spinal Cord Injury
Interventions:   Procedure: 2 hour Oral Glucose Tolerance Test;   Procedure: Fat Meal Test
Sponsors:   VA Office of Research and Development;   Kessler Foundation
Recruiting - verified June 2016

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 2016

Genetics of Atherosclerosis in Mexican Americans

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Obesity;   Atherosclerosis;   Diabetes Mellitus, Non-insulin Dependent;   Diabetes Mellitus
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified July 2008