Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Atherosclerosis-Progression in Coronary Arteries Compared to Periphery Vessels

Condition:   Atherosclerosis
Intervention:  
Sponsor:   Medical University Innsbruck
Recruiting - verified May 2017

Predictive Value Of Admission Blood Glucose Level In Patients With Acute Myocardial Infarction

Condition:   Predictive Value of Admission Blood Glucose Level in Acute Myocardial Infarction
Intervention:   Diagnostic Test: Blood Glucose Level
Sponsor:   Assiut University
Not yet recruiting - verified May 2017

Bleeding Risk Evaluation in Haemophilia Patients Under Antiplatelet Therapies

Condition:   Hemophilia
Intervention:   Other: Non interventional study
Sponsor:   Nantes University Hospital
Not yet recruiting - verified May 2017

Greek Registry - Familial Hypercholesterolaemia

Condition:   Familial Hypercholesterolemia
Intervention:  
Sponsor:   Hellenic College of Treatment of Atherosclerosis
Recruiting - verified May 2017

Digital Ankle Brachial Index (ABI) as a Screening Tool in Detecting Peripheral Arterial Disease

Conditions:   Peripheral Artery Disease;   Amputation;   Smoking;   Diabetes;   Hypercholesterolemia;   Hypertension
Intervention:   Device: ABI using QuantaFlo™
Sponsor:   St. Louis University
Recruiting - verified May 2017

Optical Coherence Tomography in Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   STEMI - ST Elevation Myocardial Infarction;   NSTEMI - Non-ST Segment Elevation MI;   Atherosclerosis, Coronary
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   Berlin Institut of Health (BIH), Germany
Recruiting - verified May 2017

TRanslesIonal Assessment of Gradients During Endovascular Therapy

Conditions:   Peripheral Arterial Disease;   Fractional Flow Reserve;   Hemodynamics
Intervention:   Device: Translesional Hemodynamic Measurement
Sponsor:   The University of Texas Health Science Center at San Antonio
Recruiting - verified May 2017

Vascular Effects of Alirocumab in Acute MI-Patients

Conditions:   Coronary Vessel;   Coronary Circulation;   Atheroma; Myocardial
Interventions:   Drug: Alirocumab 150 MG/ML;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   Regeneron Pharmaceuticals
Recruiting - verified May 2017

High-resolution MRI of Inflammation in the Intracranial Arterial Vessel Wall

Condition:   Stroke
Intervention:   Drug: Ferumoxytol Injectable Product
Sponsors:   University of Utah;   AMAG Pharmaceuticals, Inc.
Enrolling by invitation - verified May 2017

Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly

Conditions:   Cognitive Decline;   Stroke
Intervention:  
Sponsor:   University Hospital, Lille
Recruiting - verified May 2017

MGuard Stent and Microcirculation

Conditions:   Coronary Disease;   Coronary Artery Disease;   Coronary Atherosclerosis;   Cardiovascular Diseases
Interventions:   Device: MGuard stent;   Device: Drug eluting stent and bare metal stent
Sponsor:   University Hospital, Grenoble
Recruiting - verified May 2017

Individualized Response to Vitamin D Treatment Study

Condition:   Characteristics That Modify the Response to Cholecalciferol Treatment
Interventions:   Dietary Supplement: Vitamin D3;   Drug: Placebo
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation - verified May 2017

Systematic Review and Meta-Analysis on DCB vs. POBA in De-novo Femoropopliteal Disease

Conditions:   Peripheral Arterial Disease;   Intermittent Claudication
Interventions:   Device: DCB;   Device: POBA
Sponsor:   Jena University Hospital
Active, not recruiting - verified May 2017

LEADERS FREE II: BioFreedom™ Pivotal Study

Conditions:   Acute Coronary Syndrome;   High Bleeding Risk
Interventions:   Device: BioFreedom™ Drug Coated Coronary Stent System;   Drug: Dual Antiplatelet Therapy
Sponsor:   Biosensors Europe SA
Recruiting - verified May 2017

Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging(PARADIGM)

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   Yonsei University;   Montreal Heart Institute;   Hospital da Luz, Portugal;   University of California, Los Angeles;   Centro Cardiologico Monzino;   University of British Columbia;   German Heart Institute;   National Institute of Cardiology, Laranjeiras, Brazil;   Weill Medical College of Cornell University;   Cedars-Sinai Medical Center
Active, not recruiting - verified May 2017

Registry Investigating the Clinical Use and Safety of the Lutonix Drug Coated Balloon for Treatment of BTK Arteries

Condition:   Peripheral Artery Disease
Intervention:   Device: Lutonix 014 Drug Coated Balloon PTA Catheter
Sponsor:   C. R. Bard
Recruiting - verified May 2017

Effectiveness of Paclitaxel-coated Luminor® Balloon Catheter Versus Uncoated Balloon Catheter in the Arteria Femoralis Superficialis

Condition:   Peripheral Arterial Disease
Interventions:   Device: Transluminal Angioplasty with Paclitaxel-coated Luminor® Balloon Catheter in the Superficial Femoral and Popliteal Arteries;   Device: Transluminal Angioplasty with and non-coated (CE-marked) plain old angioplasty balloon (POBA) catheter
Sponsors:   Jena University Hospital;   iVascular S.L.U.;   KKS Netzwerk
Active, not recruiting - verified May 2017

Elutax-SV Drug-eluting Balloons for Below-the-knee Treatment

Conditions:   Critical Limb Ischemia;   Peripheral Artery Disease
Intervention:   Device: Angioplasty Paclitaxel-eluted balloon catheter ELUTAX SV
Sponsors:   Jena University Hospital;   Zentrum für Klinische Studien Jena;   Aachen Resonance GmbH
Recruiting - verified May 2017

Safety and Efficacy of Autologous Concentrated Bone Marrow Aspirate for Critical Limb Ischemia - Continued Access

Conditions:   Peripheral Arterial Disease;   Peripheral Vascular Diseases;   Critical Limb Ischemia
Intervention:   Device: Bone marrow concentration device
Sponsor:   Zimmer Biomet
Available - verified March 2017

Pilot Safety Study of Injectable SIS for Critical Limb Ischemia

Conditions:   Critical Limb Ischemia;   Peripheral Arterial Disease;   Peripheral Vascular Disease
Intervention:   Device: Injectable SIS
Sponsor:   Cook
Recruiting - verified May 2017

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   Cleveland Clinic Coordinating Center for Clinical Research (C5R);   Quintiles, Inc.
Active, not recruiting - verified May 2017

Comprehensive Lifestyle Modification for Patients With Hypertension and Metabolic Syndrome: a Multicenter Randomized Controlled Trial

Conditions:   Hypertension;   Metabolic Syndrome
Interventions:   Behavioral: Comprehensive Lifestyle Modification;   Behavioral: DASH
Sponsors:   Universität Duisburg-Essen;   Kliniken Essen-Mitte;   Immanuel Hospital Berlin, Berlin, Germany;   Charite University, Berlin, Germany;   University of Witten/Herdecke
Completed - verified May 2017

Swedish Drug-elution Trial in Peripheral Arterial Disease

Conditions:   Peripheral Arterial Disease;   Critical Limb Ischemia;   Intermittent Claudication
Interventions:   Procedure: Revascularization with drug-eluting technology;   Procedure: Revascularization without drug-eluting technology;   Device: drug-coated balloons and/or drug-eluting stents
Sponsors:   Sahlgrenska University Hospital, Sweden;   The Swedish Research Council;   Swedish Heart Lung Foundation;   Uppsala University;   The Swedish National Registry for Vascular Surgery
Recruiting - verified May 2017

The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI)

Conditions:   Metabolic Disease;   Cardiovascular Disease;   Inflammation
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 16, 2017

Clinical Implication of 3-vessel Fractional Flow Reserve (FFR)

Condition:   Multivessel Coronary Artery Disease
Intervention:  
Sponsors:   Seoul National University Hospital;   Samsung Medical Center;   Keimyung University Dongsan Medical Center;   Inje University;   Fu Wai Hospital, Beijing, China;   The First Affiliated Hospital with Nanjing Medical University;   Second Affiliated Hospital, School of Medicine, Zhejiang University;   Guangdong General Hospital;   Tokyo medical college hospital, Japan;   Kokura memorial hospital, Japan;   Gifu heart center, Japan;   Aichi Medical University;   Wakayama Medical University;   Queen Mary Hospital, Hong Kong;   United Christian Hospital;   National University Heart Centre, Singapore;   National Taiwan University Hospital;   Nagoya Daini Nesseki Hospital;   Ulsan University Hospital;   Ajou University School of Medicine
Active, not recruiting - verified May 2017

Paclitaxel Eluting Stent in Long SFA Obstruction: A Prospective, Randomized Comparison With Bypass Surgery

Conditions:   Chronic Lower Limb Ischemia;   Peripheral Athero Obstructive Disease;   Critical Ischemia;   Claudication
Interventions:   Procedure: bypass surgery, stent placement;   Procedure: stent placement
Sponsors:   Kuopio University Hospital;   Helsinki University Central Hospital;   Turku University Hospital;   Tampere University Hospital;   Oulu University Hospital;   Finnish Society of Interventional radiology;   North Karelia Central Hospital;   Paijat-Hame Hospital District
Recruiting - verified March 2017

Genetic Mechanisms in Human Hypertension

Condition:   Hypertension
Interventions:   Drug: Para-aminohippuric Acid;   Drug: Angiotensin II;   Drug: Norepinephrine
Sponsor:   Brigham and Women's Hospital
Active, not recruiting - verified May 2017

Vascular Dysfunction in Diabetes: Genes and Hormones

Condition:   Diabetes Mellitus
Interventions:   Drug: Para-aminohippuric Acid;   Drug: Angiotensin II;   Drug: Norepinephrine
Sponsor:   Brigham and Women's Hospital
Active, not recruiting - verified May 2017

Comparative Effectiveness Research Study of Peripheral Arterial Disease (PAD)

Conditions:   Peripheral Arterial Disease;   Claudication
Intervention:  
Sponsor:   University of Washington
Completed - verified May 2017

Patients' Perspectives of Factors That Support the Management of Peripheral Arterial Disease for Improved Outcomes

Condition:   Peripheral Arterial Diseases
Intervention:  
Sponsor:   VA Eastern Colorado Health Care System
Completed - verified May 2017

ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

Conditions:   Cardiovascular Disease;   Coronary Artery Calcification
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified May 17, 2017

Technical Development of Cardiovascular Magnetic Resonance Imaging

Condition:   Peripheral Artery Disease
Intervention:   Procedure: MRI
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 19, 2017

Epidemiology: Oxidative Stress and Early Atherosclerosis

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Atherosclerosis;   Coronary Arteriosclerosis
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Northwestern University;   Kaiser Permanente;   University of Alabama at Birmingham
Active, not recruiting - verified May 2017

Epidemiology of Venous Thrombosis and Pulmonary Embolism

Conditions:   Cardiovascular Diseases;   Pulmonary Embolism;   Venous Thrombosis
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified May 2017