Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Assessment of Osteoblastic Activity With 18F-Fluoride in Aortic Bioprosthesis Structural Valve Dysfunction (SVD)

Condition:   Aortic Bioprosthesis Structural Valve Dysfunction
Intervention:   Other: 18F-Fluoride PET-CT ; CT calcium scoring ; 18F-FDG PET-CT
Sponsor:   Nantes University Hospital
Not yet recruiting - verified January 2017

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

Condition:   Mitral Valve Failure
Interventions:   Device: Edwards SAPIEN 3 transcatheter heart valve;   Device: ASHI INTECC Astato XS 20
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified January 2017

Evaluation of the BARD® True™ Flow Valvuloplasty Perfusion Catheter for Aortic Valve Dilatation

Condition:   Aortic Valve Stenosis
Intervention:   Device: True™ Flow Valvuloplasty Perfusion Catheter
Sponsor:   C. R. Bard
Completed - verified January 2017

Comparison of a Rivaroxaban-based Strategy With an Antiplatelet-based Strategy Following Successful TAVR for the Prevention of Leaflet Thickening and Reduced Leaflet Motion as Evaluated by Four-dimensional, Volume-rendered Computed Tomography (4DCT)

Conditions:   Aortic Valve Stenosis;   Cardiovascular Diseases;   Heart Valve Diseases;   Ventricular Outflow Obstruction;   Thrombosis
Interventions:   Drug: Acetylicsalicylic acid;   Drug: Clopidogrel;   Drug: Rivaroxaban
Sponsors:   ECRI bv;   Rigshospitalet, Denmark;   Bayer;   Cardialysis BV
Recruiting - verified January 2017

The REFLECT Trial: Cerebral Protection to Reduce Cerebral Embolic Lesions After Transcatheter Aortic Valve Implantation

Condition:   Symptomatic Aortic Stenosis
Interventions:   Device: Embolic Protection Device;   Procedure: Transcatheter aortic valve implantation (TAVI)
Sponsor:   Keystone Heart
Recruiting - verified January 2017

Interest of Remote Ischemic Preconditioning for Prevention of Contrast Medium-induced Nephropathy in High Risk Patients

Condition:   Nephropathy
Interventions:   Other: Remote Ischemic Preconditioning (RIPC);   Other: SHAM Remote Ischemic Preconditioning (SHAM RIPC)
Sponsor:   Rennes University Hospital
Recruiting - verified January 2017

Fat Distribution and Glucose Metabolism in Williams Syndrome

Condition:   Williams Syndrome
Sponsor:   Massachusetts General Hospital
Completed - verified January 2017

Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve

Conditions:   Aortic Valve Stenosis;   Aortic Valve Stenosis With Insufficiency;   Regurgitation, Aortic Valve;   Aortic Valve Incompetence
Intervention:   Device: EDWARDS INTUITY valve
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified January 2017

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

Condition:   Severe Aortic Stenosis
Interventions:   Device: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI);   Procedure: Surgical Aortic Valve Replacement (SAVR) (Not applicable for Single Arm);   Device: Medtronic CoreValve® Evolut R System Transcatheter Aortic Valve Implantation (TAVI)
Sponsor:   Medtronic Cardiovascular
Recruiting - verified January 2017

Echocardiographic Assessment of Cardiovascular Changes in Long Term Space Flight

Conditions:   Aortic Valve Insufficiency;   Aortic Valve Stenosis
Sponsors:   The Cleveland Clinic;   National Space Biomedical Research Institute
Terminated - verified January 2008

Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in Space

Conditions:   Aortic Valve Insufficiency;   Aortic Stenosis
Sponsors:   The Cleveland Clinic;   National Space Biomedical Research Institute
Terminated - verified January 2008

Diagnostic Three Dimensional Echocardiography Study Protocol

Conditions:   Aortic Valve Stenosis;   Aortic Valve Insufficiency
Sponsors:   The Cleveland Clinic;   National Space Biomedical Research Institute
Withdrawn - verified January 2008