Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Revascularization in Patients Undergoing Transcatheter Aortic Valve Implantation

Conditions:   Coronary Artery Disease;   Aortic Valve Stenosis;   TAVI;   PCI
Intervention:   Procedure: PCI
Sponsors:   Rigshospitalet, Denmark;   Aarhus University Hospital;   Aalborg Universitetshospital;   Odense University Hospital;   Lund University Hospital;   Karolinska University Hospital;   Rikshospitalet University Hospital;   Haukeland University Hospital;   Helsinki University Central Hospital;   Tampere University Hospital;   Oulu University Hospital
Not yet recruiting - verified February 2017

Assessment of the St Jude Medical Portico Resheathable Aortic Valve System-Alternative Access

Condition:   Aortic Valve Stenosis
Intervention:   Device: TAVI
Sponsor:   St. Jude Medical
Not yet recruiting - verified February 2017

Metabolomics Study of Cardiomyopathy

Conditions:   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Arrhythmogenic Right Ventricular Cardiomyopathy;   Left Ventricular Non-compaction;   Restrictive Cardiomyopathy
Intervention:  
Sponsor:   Beijing Institute of Heart, Lung and Blood Vessel Diseases
Recruiting - verified February 2017

Safety and Efficacy of the Symetis ACURATE Neo/TF Compared to the Edwards SAPIEN 3 Bioprosthesis.

Condition:   Aortic Valve Stenosis
Interventions:   Device: Symetis ACURATE neo/TF transfemoral TAVI system;   Device: Edwards Sapien 3 Transcatheter Heart Valve
Sponsors:   University Hospital Inselspital, Berne;   Kerckhoff Heart Center
Recruiting - verified February 2017

UTSW HP [13-C] Pyruvate Injection in HCM

Condition:   Cardiomyopathy, Hypertrophic
Intervention:   Drug: Hyperpolarized 13C-Pyruvate
Sponsor:   University of Texas Southwestern Medical Center
Not yet recruiting - verified February 2017

Impact of Elastin Mediated Vascular Stiffness on the Brain

Conditions:   Williams Syndrome;   Supravalvular Aortic Stenosis;   Cardiovascular Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 31, 2016

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

Conditions:   Cardiomyopathy, Hypertrophic;   Cardiomyopathy, Hypertrophic, Familial
Intervention:   Drug: Perhexiline
Sponsor:   Heart Metabolics Limited
Recruiting - verified February 2017

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage

Condition:   Aortic Valve Disorder
Interventions:   Device: Lotus Heart valve system;   Device: WATCHMAN
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified February 2017

Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis

Conditions:   Symptomatic Aortic Stenosis;   Eligible for Transcatheter Aortic Valve Replacement
Interventions:   Drug: Apixaban;   Drug: Standard of care
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Action Research Group;   Bristol-Meyers Squibb & Pfizer
Recruiting - verified February 2017

BIOVALVE - I / II Clincial Investigation

Conditions:   Heart Valve Diseases;   Aortic Valve Stenosis
Intervention:   Device: BIOVALVE prosthesis
Sponsors:   Biotronik AG;   Medstar Health Research Institute
Recruiting - verified February 2017

Balloon Expandable Transcatheter Aortic Valve Implantation Without Predilation of the Aortic Valve

Condition:   Aortic Valve Stenosis
Interventions:   Procedure: BAV;   Procedure: without BAV
Sponsor:   Institut für Pharmakologie und Präventive Medizin
Completed - verified February 2017

PERIGON Pivotal Trial

Condition:   Aortic Stenosis
Intervention:   Device: Model 400 aortic valve bioprosthesis
Sponsors:   Medtronic Cardiovascular;   Medtronic
Recruiting - verified February 2017

The PARTNER TRIAL - Post Approval Study Part II

Conditions:   Severe;   Symptomatic;   Calcific Aortic Stenosis
Intervention:   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Sponsors:   Edwards Lifesciences;   American College of Cardiology;   Society of Thoracic Surgeons (STS)
Active, not recruiting - verified February 2017

ROUTE Registry Of the Utilisation of the Transaortic (Tao) TAVI Approach Using the Edwards Sapien XT Valve

Condition:   Aortic Stenosis
Intervention:  
Sponsor:   Institut für Pharmakologie und Präventive Medizin
Completed - verified February 2017

The SOLACE-AU Clinical Trial

Condition:   Severe, Symptomatic Aortic Stenosis
Intervention:   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Sponsors:   Edwards Lifesciences;   Pacific Clinical Research Group
Active, not recruiting - verified February 2017

SWISS TAVI Registry

Condition:   Aortic Stenosis
Intervention:   Procedure: Transcatheter Aortic Valve Implantation
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified February 2017