Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Lp(a) and Aortic Valve Calcification

Condition:   Heterozygous Familial Hypercholesterolemia
Sponsors:   Laval University;   Amgen
Not yet recruiting - verified November 2016

Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly

Conditions:   Cognitive Decline;   Stroke
Sponsor:   University Hospital, Lille
Not yet recruiting - verified November 2016

Saint Luc Valve Registry

Condition:   Valvular Heart Disease Stenosis and Regurgitation (Diagnosis)
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Recruiting - verified November 2016

Rivaroxaban or Aspirin for Biological Aortic Prosthesis

Conditions:   Aortic Stenosis;   Aortic Regurgitation;   Thrombosis
Interventions:   Drug: Rivaroxaban 10 MG;   Drug: Aspirin
Sponsors:   Christian Torp-Pedersen;   Aalborg Universitetshospital;   Aarhus University Hospital;   Odense University Hospital;   Rigshospitalet, Denmark
Not yet recruiting - verified November 2016

Protamine Sulfate During Transcatheter Aortic Valve Implantation

Condition:   Aortic Valve Stenosis
Interventions:   Drug: Protamine sulfate;   Drug: 0.9% NaCl
Sponsor:   Medical University of Warsaw
Not yet recruiting - verified November 2016

Evaluating the Risk of Cognitive Impairment After Surgical and Transcatheter Aortic Valve Replacement

Conditions:   Cardiovascular Disease;   Aortic Valve Stenosis;   Cognitive Assessments;   Valve Surgery;   Transcatheter Valve Replacement;   Surgical Valve Replacement
Intervention:   Other: Observational/Cognitive Assessment
Sponsors:   Minnesota Veterans Medical Research and Education Foundation;   Minneapolis Veterans Affairs Health Care System
Recruiting - verified November 2016

TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis

Condition:   Aortic Valve Stenosis
Interventions:   Device: SAPIEN 3;   Procedure: SAVR
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Withdrawn - verified November 2016

Evaluating the Effectiveness of Atorvastatin on the Progression of Aortic Dilatation and Valvular Degeneration in Patients With Bicuspid Aortic Valve

Condition:   Bicuspid Aortic Valve
Interventions:   Drug: Atorvastatin;   Drug: Placebo
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Recruiting - verified November 2016

CoreValve™ Evolut R™ FORWARD Study

Condition:   Aortic Valve Stenosis
Intervention:   Device: Medtronic CoreValve™ Evolut R™ System
Sponsor:   Medtronic Cardiovascular
Active, not recruiting - verified November 2016

Cerebral Protection to Reduce Cerebral Embolic Lesions After Transcatheter Aortic Valve Implantation

Condition:   Symptomatic Aortic Stenosis
Interventions:   Device: Embolic Protection Device;   Procedure: ranscatheter aortic valve implantation (TAVI)
Sponsor:   Keystone Heart
Recruiting - verified November 2016

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Eleclazine;   Drug: Placebo
Sponsor:   Gilead Sciences
Recruiting - verified November 2016

Indication of Permanent Cardiac Parcing After Tanscatheter Aortic Valve Implantation

Condition:   Aortic Valve Stenosis
Interventions:   Device: Pacemaker SORIN Group KORA DR;   Procedure: transcatheter aortic valve implantation (TAVI)
Sponsor:   University Hospital, Montpellier
Completed - verified November 2016

Edwards SAPIEN Periprosthetic Leakage Evaluation Versus Medtronic CoreValve in Transfemoral Aortic Valve Implantation (the ELECT Trial)

Condition:   Periprosthetic Aortic Valve Regurgitation After TAVI
Interventions:   Procedure: Transcatheter aortic valve replacement;   Device: Medtronic CoreValve system;   Device: Edwards SAPIEN bioprosthesis
Sponsor:   UMC Utrecht
Terminated - verified November 2016

Balloon Aortic Valvuloplasty Performed Without Heparin to Decrease Vascular and Bleeding Complications of the Procedure

Condition:   Aortic Stenosis, Non-rheumatic
Interventions:   Drug: Heparin;   Drug: NaCl
Sponsor:   University Hospital, Montpellier
Terminated - verified November 2016

5 Year Observation of Patients With PORTICO Valves

Condition:   Aortic Valve Stenosis
Interventions:   Device: St Jude Medical Portico replacement aortic valve;   Procedure: Transcatheter Aortic Valve Implant
Sponsor:   St. Jude Medical
Recruiting - verified November 2016

Compassionate Use of Triheptanoin (C7) for Inherited Disorders of Energy Metabolism

Conditions:   Very Long-chain acylCoA Dehydrogenase (VLCAD) Deficiency;   Carnitine Palmitoyltransferase Deficiencies (CPT1, CPT2);   Mitochondrial Trifunctional Protein Deficiency;   Long-chain Hydroxyacyl-CoA Dehydrogenase Deficiency;   Glycogen Storage Disorders;   Pyruvate Carboxylase Deficiency Disease;   ACYL-CoA DEHYDROGENASE FAMILY, MEMBER 9, DEFICIENCY of;   Barth Syndrome
Intervention:   Drug: triheptanoin
Sponsors:   University of Pittsburgh;   Ultragenyx Pharmaceutical Inc
Available - verified November 2016

Clinical Investigation of the Freedom SOLO Stentless Heart Valve

Condition:   Heart Valve Diseases
Intervention:   Device: Freedom SOLO
Sponsor:   LivaNova
Active, not recruiting - verified November 2016

The Effect of Glucose-Insulin-Potassium Infusion in Patients Undergoing Cardiac Surgery

Conditions:   Aortic Stenosis;   Coronary Heart Disease;   Heart Failure
Interventions:   Drug: Glucose-insulin-potassium;   Drug: Placebo
Sponsor:   Christoph Ellenberger
Completed - verified November 2016

Genomic Investigation of Cardiovascular Diseases

Conditions:   Coronary Artery Disease;   Myocardial Infarction;   Atrial Fibrillation;   Aortic Stenosis;   Mitral Regurgitation;   Idiopathic Cardiomyopathy
Sponsor:   Scripps Translational Science Institute
Active, not recruiting - verified November 2016