Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Direct Left Ventricular Rapid Pacing Via the Valve Delivery Guide-wire in TAVI

Condition:   Aortic Valve Stenosis
Interventions:   Device: pacing catheter;   Device: two alligator clamps and a curved needle
Sponsor:   Centre Recherche Cardio Vasculaire Alpes
Not yet recruiting - verified May 2016

A STEP for Patients Prior to Undergoing TAVR: A Pilot Study

Conditions:   Frail Elderly;   Aortic Valve Stenosis
Intervention:   Behavioral: Supervised TAVR Exercise Program
Sponsors:   OSF Healthcare System;   OSF St. Francis Medical Center;   HeartCare Midwest;   University of Illinois College of Medicine at Peoria
Recruiting - verified April 2016

Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency Department

Condition:   Syncope
Intervention:  
Sponsor:   University of Turin, Italy
Recruiting - verified May 2016

Performing a Low-dose, Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA

Conditions:   Stroke;   Ischemic Attack, Transient
Interventions:   Other: Routine Imaging Assessment;   Device: LDWBA first (CT scan)
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified May 2016

Interest of Remote Ischemic Preconditioning for Prevention of Contrast Medium-induced Nephropathy in High Risk Patients

Condition:   Nephropathy
Interventions:   Other: Remote Ischemic Preconditioning (RIPC);   Other: SHAM Remote Ischemic Preconditioning (SHAM RIPC)
Sponsor:   Rennes University Hospital
Recruiting - verified May 2016

Feasibility And Safety of Early Discharge After Transfemoral Transcatheter Aortic Valve Implantation

Condition:   Aortic Stenosis
Intervention:   Device: TF TAVI
Sponsors:   Institut für Pharmakologie und Präventive Medizin;   Edwards Lifesciences
Recruiting - verified May 2016

Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease

Condition:   Coronary Artery Disease
Interventions:   Procedure: Computed tomography angiography (cardiac CT);   Procedure: Invasive coronary angiography (ICA)
Sponsor:   Charite University, Berlin, Germany
Recruiting - verified May 2016

Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic Access

Condition:   Aortic Valve Stenosis
Intervention:   Procedure: CA-TAVR
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Quality of Care in AS IMPULSE Study

Condition:   Aortic Valve Stenosis
Intervention:   Other: Early Information
Sponsors:   Institut für Pharmakologie und Präventive Medizin;   Edwards Lifesciences
Recruiting - verified May 2016

Cerebral Protection in Transcatheter Aortic Valve Replacement

Condition:   Severe Symptomatic Calcified Native Aortic Valve Stenosis
Interventions:   Device: Cerebral Protection System-The SENTINEL System with TAVR;   Device: TAVR
Sponsor:   Claret Medical
Active, not recruiting - verified May 2016

Regression of Myocardial Fibrosis After Aortic Valve Replacement

Condition:   Aortic Stenosis
Intervention:  
Sponsor:   University College, London
Completed - verified May 2015

Clinical Outcome of Patients With Low-gradient Severe Aortic Stenosis

Condition:   Aortic Stenosis
Intervention:  
Sponsor:   Sheba Medical Center
Recruiting - verified May 2016

Functional and Quality of Life Improvement Following Transcatheter Heart Valve Implantation

Conditions:   Trans Catheter Aortic Valve;   Aortic Stenosis
Intervention:  
Sponsor:   Sheba Medical Center
Recruiting - verified May 2016

Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial

Condition:   Aortic Valve Stenosis
Interventions:   Device: Portico transcatheter aortic valve;   Device: Commercially available transcatheter aortic valve
Sponsor:   St. Jude Medical
Recruiting - verified May 2016

Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES)

Conditions:   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Restrictive Cardiomyopathy
Intervention:  
Sponsors:   Wayne State University;   New England Research Institutes;   Children's Hospital Medical Center, Cincinnati;   Washington University School of Medicine;   Children's Hospital of Philadelphia;   Columbia University;   Children's Hospital Boston;   Ann & Robert H Lurie Children's Hospital of Chicago;   Primary Children's Hospital;   Monroe Carell Jr. Children's Hospital at Vanderbilt;   Stollery Children's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   University of Miami;   Children's Hospital Colorado;   Indiana University
Recruiting - verified May 2016

Cardiac Biomarkers in Pediatric Cardiomyopathy (PCM Biomarkers)

Conditions:   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy
Intervention:  
Sponsors:   Wayne State University;   New England Research Institutes;   Washington University School of Medicine;   Children's Hospital Boston;   Columbia University;   Children's Hospital of Philadelphia;   Ann & Robert H Lurie Children's Hospital of Chicago;   Primary Children's Hospital;   Monroe Carell Jr. Children's Hospital at Vanderbilt;   Stollery Children's Hospital;   Children's Hospital Medical Center, Cincinnati;   Montefiore Medical Center;   Children's Hospital Colorado;   Le Bonheur Children's Hospital;   Children's Hospital of Pittsburgh
Active, not recruiting - verified May 2016

Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Valsartan;   Drug: Placebo
Sponsors:   New England Research Institutes;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2016

Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome

Conditions:   Turner Syndrome;   Bicuspid Aortic Valve;   Marfan Syndrome
Intervention:  
Sponsor:   University of Aarhus
Completed - verified June 2015

Hemodynamic Comparison of Tissue Aortic Valves

Condition:   Aortic Valve Stenosis
Intervention:   Device: Aortic valve replacement
Sponsor:   University of Michigan
Completed - verified May 2016

TAVI Protocol - Paravertebral Block Study

Conditions:   Aortic Valve Replacement;   Aortic Stenosis
Intervention:   Other: Thoracic paravertebral block (PVB)
Sponsor:   University Health Network, Toronto
Recruiting - verified May 2016