Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification

Condition:   Aortic Valve Stenosis
Interventions:   Drug: Ataciguat (HMR1766);   Other: Placebo Comparator: Matching Placebo
Sponsors:   Mayo Clinic;   Sanofi;   National Institutes of Health (NIH)
Not yet recruiting - verified June 2015

Assessment of the Prognosis of Persistent Left Bundle Branch Block (LBBB)After Transcatheter Aortic Valve Implantation (TAVI ) by an Electrophysiological and Remote Monitoring Risk-adapted Algorithm

Condition:   Post-TAVI
Interventions:   Other: pacemaker implantation;   Other: holter implantation
Sponsors:   University Hospital, Clermont-Ferrand;   Sorin Group;   Biotronik France
Recruiting - verified June 2015

Inflammation and Thrombosis in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (TAVR)

Conditions:   Aortic Stenosis;   Inflammation;   Thrombosis
Interventions:   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsor:   University Hospital Case Medical Center
Not yet recruiting - verified June 2015

Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.

Conditions:   Ischaemic Heart Disease;   Aortic Stenosis
Interventions:   Drug: Remifentanil;   Drug: Sufentanil
Sponsor:   Aarhus University Hospital
Active, not recruiting - verified June 2015

Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency.

Condition:   Hypertrophic Obstructive Cardiomyopathy
Interventions:   Procedure: myoectomy;   Procedure: Mitral valve surgery;   Procedure: Mitral valve surgery
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Completed - verified July 2015

The Medtronic CoreValve™ Evolut R™ CE Mark Clinical Study

Condition:   Aortic Stenosis
Intervention:   Device: The CoreValve™ Evolut R TAV™ system
Sponsors:   Medtronic Cardiovascular;   Medtronic
Active, not recruiting - verified June 2015

Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome

Conditions:   Turner Syndrome;   Bicuspid Aortic Valve;   Marfan Syndrome
Sponsor:   University of Aarhus
Recruiting - verified June 2015

ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)

Conditions:   Aortic Stenosis;   Mitral Stenosis;   Aortic Valve Insufficiency;   Mitral Valve Insufficiency;   Heart Failure
Intervention:   Device: Edwards Aortic and Mitral Bioprostheses Models 11000A and 11000M
Sponsor:   Edwards Lifesciences
Recruiting - verified June 2015

Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve

Conditions:   Aortic Valve Stenosis;   Aortic Valve Stenosis With Insufficiency;   Regurgitation, Aortic Valve;   Aortic Valve Incompetence
Intervention:   Device: EDWARDS INTUITY valve
Sponsor:   Edwards Lifesciences
Recruiting - verified June 2015

Carpentier-Edwards PERIMOUNT Magna Ease Pericardial Bioprosthesis, Model 3300TFX

Conditions:   Coronary Artery Disease;   Aortic Valve Disorder;   Heart Failure;   Aortic Valve Stenosis;   Aortic Valve Insufficiency
Intervention:   Device: Implantation of CEP Magna Ease Model 3300TFX
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified June 2015

Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis

Condition:   Aortic Stenosis
Intervention:   Procedure: Early surgery
Sponsors:   Asan Medical Center;   Korea Institute of Medicine
Active, not recruiting - verified June 2015

CoreValve® System Australia/New Zealand Clinical Study

Condition:   Aortic Valve Stenosis
Intervention:   Device: Medtronic CoreValve® System
Sponsors:   Medtronic Heart Valves;   Medtronic Australasia
Active, not recruiting - verified June 2015

Follow Up on Freestyle Valves in Children

Conditions:   Right Ventricle;   Pulmonary Valve Stenosis;   Pulmonary Valve Atresia
Intervention:   Procedure: Echocardiogram
Sponsor:   Emory University
Active, not recruiting - verified June 2015

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