Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Ascending Aortic Dilation in BiAV After TAVR

Condition:   Aortic Valve Stenosis
Intervention:   Other: diagnosed as bicuspid aortic valve
Sponsor:   Seoul National University Hospital
Recruiting - verified February 2017

Assessment of the St Jude Medical Portico Resheathable Aortic Valve System-Alternative Access

Condition:   Aortic Valve Stenosis
Intervention:   Device: TAVI
Sponsor:   St. Jude Medical
Not yet recruiting - verified February 2017

PCSK9 Inhibitors in the Progression of Aortic Stenosis

Condition:   Aortic Valve Stenosis
Interventions:   Drug: PCSK9 Inhibitor [EPC];   Drug: Placebos
Sponsor:   Seoul National University Hospital
Not yet recruiting - verified February 2017

Stress Echo 2020 - The International Stress Echo Study

Conditions:   Coronary Artery Disease;   Heart Failure;   Hypertrophic Cardiomyopathy;   Aortic Valve Disease;   Athletes Heart;   Tetralogy of Fallot;   Pulmonary Arterial Hypertension
Interventions:   Procedure: Left ventricular contractile reserve SE;   Procedure: B-lines SE;   Procedure: Left ventricular outflow tract gradient SE;   Procedure: Diastolic function SE;   Procedure: Mitral regurgitation SE;   Procedure: Pulmonary hemodynamics SE;   Procedure: Coronary flow reserve SE
Sponsors:   Fatebenefratelli Hospital;   Institute of Clinical Physiology, CNR, Pisa,Italy;   Salerno Hospital, Italy;   Monaldi Hospital, Napoli, Italy;   University of Pisa, Italy;   San Luca Hospital, Lucca, Italy;   Careggi University Hospital, Florence, Italy;   Federico II University, Napoli, Italy;   San Carlo Hospital, Potenza, Italy;   Royal Brompton & Harefield NHS Foundation Trust;   Ospedale dell'Angelo, Venezia-Mestre, Italy;   University of Parma;   Hospital Clinics, Trieste, Italy;   Rio Grande do Sul University Hospital, Porto Alegre, Brasil;   Hospital San José, Criciuma, Brasil;   Hospital San Vicente de Paulo, Passo Fundo, Brasil;   University of Belgrade;   University of Szeged, Hungary;   Elisabeth Hospital, Hodmezovasarhely, Hungary;   University of Padua, Italy;   Sandro Pertini Hospital, Rome, Italy;   Medical Center Hospital of the Republic of Kazakhstan, Astana, Kazakhstan;   Hospital Clinics, Bari, Italy;   Ospedale Nottola, Siena, Italy;   University of Catania, Italy;   Medika Cardiocenter, Saint Petersburg, Russian Federation
Recruiting - verified February 2017

Safety and Efficacy of the Symetis ACURATE Neo/TF Compared to the Edwards SAPIEN 3 Bioprosthesis.

Condition:   Aortic Valve Stenosis
Interventions:   Device: Symetis ACURATE neo/TF transfemoral TAVI system;   Device: Edwards Sapien 3 Transcatheter Heart Valve
Sponsors:   University Hospital Inselspital, Berne;   Kerckhoff Heart Center
Recruiting - verified February 2017

UTSW HP [13-C] Pyruvate Injection in HCM

Condition:   Cardiomyopathy, Hypertrophic
Intervention:   Drug: Hyperpolarized 13C-Pyruvate
Sponsor:   University of Texas Southwestern Medical Center
Not yet recruiting - verified February 2017

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

Conditions:   Cardiomyopathy, Hypertrophic;   Cardiomyopathy, Hypertrophic, Familial
Intervention:   Drug: Perhexiline
Sponsor:   Heart Metabolics Limited
Recruiting - verified February 2017

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage

Condition:   Aortic Valve Disorder
Interventions:   Device: Lotus Heart valve system;   Device: WATCHMAN
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified February 2017

Von Willebrand Factor As a Biological Sensor of Blood Flow in Percutaneous Cardiac Procedure

Conditions:   Heart Failure;   Aortic Stenosis
Intervention:   Device: cardiac devices
Sponsor:   University Hospital, Lille
Recruiting - verified February 2017

Hypertrophic Cardiomyopathy Symptom Release by BX1514M

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Treatment BX1514M;   Drug: Placebo;   Other: Walk distance test;   Other: Exercise echocardiography
Sponsor:   University Hospital, Bordeaux
Completed - verified February 2017

BIOVALVE - I / II Clincial Investigation

Conditions:   Heart Valve Diseases;   Aortic Valve Stenosis
Intervention:   Device: BIOVALVE prosthesis
Sponsors:   Biotronik AG;   Medstar Health Research Institute
Recruiting - verified February 2017

The PARTNER TRIAL - Post Approval Study Part II

Conditions:   Severe;   Symptomatic;   Calcific Aortic Stenosis
Intervention:   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Sponsors:   Edwards Lifesciences;   American College of Cardiology;   Society of Thoracic Surgeons (STS)
Active, not recruiting - verified February 2017

Cardiac Biomarkers in Pediatric Cardiomyopathy (PCM Biomarkers)

Conditions:   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy
Intervention:  
Sponsors:   Wayne State University;   New England Research Institutes;   Washington University School of Medicine;   Boston Children’s Hospital;   Columbia University;   Children's Hospital of Philadelphia;   Ann & Robert H Lurie Children's Hospital of Chicago;   Primary Children's Hospital;   Monroe Carell Jr. Children's Hospital at Vanderbilt;   Stollery Children's Hospital;   Children's Hospital Medical Center, Cincinnati;   Montefiore Medical Center;   Children's Hospital Colorado;   Le Bonheur Children's Hospital;   Children's Hospital of Pittsburgh
Active, not recruiting - verified February 2017

Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES)

Conditions:   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Restrictive Cardiomyopathy
Intervention:  
Sponsors:   Wayne State University;   New England Research Institutes;   Children's Hospital Medical Center, Cincinnati;   Washington University School of Medicine;   Children's Hospital of Philadelphia;   Columbia University;   Boston Children’s Hospital;   Ann & Robert H Lurie Children's Hospital of Chicago;   Primary Children's Hospital;   Monroe Carell Jr. Children's Hospital at Vanderbilt;   Stollery Children's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   University of Miami;   Children's Hospital Colorado;   Indiana University
Active, not recruiting - verified February 2017

The SOLACE-AU Clinical Trial

Condition:   Severe, Symptomatic Aortic Stenosis
Intervention:   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Sponsors:   Edwards Lifesciences;   Pacific Clinical Research Group
Active, not recruiting - verified February 2017

SWISS TAVI Registry

Condition:   Aortic Stenosis
Intervention:   Procedure: Transcatheter Aortic Valve Implantation
Sponsor:   University Hospital Inselspital, Berne
Recruiting - verified February 2017