Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Comparing the Effects on Cardiac Function of Levosimendan Versus Milrinone.

Conditions:   Heart Failure, Diastolic;   Aortic Valve Stenosis
Interventions:   Drug: Levosimendan;   Drug: Milrinone
Sponsor:   Sahlgrenska University Hospital, Sweden
Recruiting - verified April 2015

Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias

Conditions:   Inherited Cardiac Arrythmias;   Long QT Syndrome (LQTS);   Brugada Syndrome (BrS);   Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT);   Early Repolarization Syndrome (ERS);   Arrhythmogenic Cardiomyopathy (AC, ARVD/C);   Hypertrophic Cardiomyopathy (HCM);   Dilated Cardiomyopathy (DCM);   Muscular Dystrophies (Duchenne, Becker, Myotonic Dystrophy);   Normal Control Subjects
Intervention:  
Sponsor:   Johns Hopkins University
Enrolling by invitation - verified April 2015

Individualized Early Risk Assessment for Heart Diseases

Conditions:   Cardiomyopathy, Hypertrophic;   Cardiomyopathy, Dilated;   Heart Failure With Normal Ejection Fraction
Intervention:   Other: Skin biopsy, genotyping and disease phenotyping
Sponsor:   Universitätsklinikum Hamburg-Eppendorf
Recruiting - verified April 2015

Assessment of Wall Thickness in Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Procedure: Noncontrast echocardiography;   Procedure: Contrast Echocardiography;   Procedure: Cardiac magnetic resonance imaging
Sponsors:   Mayo Clinic;   GE Healthcare
Recruiting - verified April 2015

Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery.

Conditions:   Patients Waiting for Elective Isolated Coronary Artery Bypass Grafting (CABG);   Patients Waiting for Aortic Valve Repair/Replacement for Moderate Aortic Stenosis or Severe Regurgitation;   Patients Waiting for Mitral Valve Repair/Replacement for Moderate Stenosis or Severe Regurgitation;   Patients Waiting for Combined CABG/Valve Procedures.
Intervention:   Behavioral: Prehab Intervention
Sponsor:   St. Boniface General Hospital Research Centre
Recruiting - verified April 2015

Early Aortic Valve Lipoprotein(a) Lowering Trial

Condition:   Aortic Stenosis and Lipoprotein(a) Levels
Interventions:   Drug: Extended release Niacin;   Drug: Placebo Comparator
Sponsors:   George Thanassoulis;   Jewish General Hospital;   Laval University;   Quebec Heart Institute
Recruiting - verified April 2015

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Other: None - this is an observational study
Sponsors:   University of Virginia;   National Heart, Lung, and Blood Institute (NHLBI);   Oxford University Hospitals NHS Trust
Recruiting - verified April 2015

Aortic Stenosis Pre-Transcatheter Aortic Valve Replacement (TAVR) Procedure CT Scan

Condition:   Aortic Valve Stenosis
Intervention:   Drug: Low-volume, low-concentration contrast (iodixanol - Visipaque 270) CT scan
Sponsors:   Medical University of South Carolina;   General Electric
Active, not recruiting - verified April 2015

International, Multi-center, Open-label, Randomized Controlled Trial in Patients Undergoing TAVR to Determine the Treatment Effect (Both Safety and Efficacy) of Using Bivalirudin Instead of UFH.

Conditions:   Severe Aortic Stenosis;   Aortic Valve Insufficiency;   Transcatheter Aortic Valve Replacement;   Aortic Valve Replacement
Intervention:   Procedure: Trans-Aortic Valve Replacement
Sponsor:   The Medicines Company
Recruiting - verified October 2014

Assessment Of The St. Jude Medical Portico™ Transcatheter Aortic Valve Implant (TAVI) and SJM TAVI Transfemoral Delivery System

Condition:   Symptomatic Aortic Stenosis
Intervention:   Device: Transcatheter Aortic Valve Implantation
Sponsor:   St. Jude Medical
Recruiting - verified April 2015

Study to Develop a Non-invasive Marker for Monitoring Myocardial Fibrosis

Conditions:   Hypertrophic Cardiomyopathy;   Acute Coronary Syndrome
Intervention:   Radiation: 99mTc-NC100692
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting - verified April 2015

Genetic of Aortic Valve Stenosis - Clinical and Therapeutic Implications

Condition:   Aortic Valve Stenosis
Intervention:  
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - verified June 2011

Aortic Stenosis in Elderly : Determinant of Progression

Conditions:   Aortic Stenosis;   Elderly Gravida
Intervention:  
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting - verified June 2011

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