Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification

Condition:   Aortic Valve Stenosis
Interventions:   Drug: Ataciguat (HMR1766);   Other: Placebo Comparator: Matching Placebo
Sponsors:   Mayo Clinic;   Sanofi;   National Institutes of Health (NIH)
Not yet recruiting - verified June 2015

Assessment of the Prognosis of Persistent Left Bundle Branch Block (LBBB)After Transcatheter Aortic Valve Implantation (TAVI ) by an Electrophysiological and Remote Monitoring Risk-adapted Algorithm

Condition:   Post-TAVI
Interventions:   Other: pacemaker implantation;   Other: holter implantation
Sponsors:   University Hospital, Clermont-Ferrand;   Sorin Group;   Biotronik France
Recruiting - verified June 2015

Neuroprotection in Patients Undergoing Aortic Valve Replacement

Conditions:   Aortic Stenosis;   Brain Infarction;   Cerebrovascular Accident;   Stroke
Interventions:   Device: Embol-X Embolic Protection Device;   Device: CardioGard Cannula
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 2015

Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-461

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Drug: MYK-461
Sponsor:   MyoKardia, Inc.
Recruiting - verified June 2015

The Multidisciplinary, Multimodality, But Minimalist Approach to Transfemoral Transcatheter Aortic Valve Replacement

Condition:   Aortic Valve Stenosis
Intervention:   Other: Vancouver 3M Clinical Pathway
Sponsors:   BC Centre for Improved Cardiovascular Health;   University of British Columbia
Recruiting - verified May 2015

Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic Access

Condition:   Aortic Valve Stenosis
Intervention:   Procedure: CA-TAVR
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified September 2014

Pilot Study of Cognitive and Functional Outcomes Following TAVI

Condition:   Aortic Stenosis
Sponsor:   Sunnybrook Health Sciences Centre
Recruiting - verified June 2015

Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.

Conditions:   Ischaemic Heart Disease;   Aortic Stenosis
Interventions:   Drug: Remifentanil;   Drug: Sufentanil
Sponsor:   Aarhus University Hospital
Active, not recruiting - verified June 2015

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Other: None - this is an observational study
Sponsors:   University of Virginia;   National Heart, Lung, and Blood Institute (NHLBI);   Oxford University Hospitals NHS Trust
Recruiting - verified June 2015

Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome

Conditions:   Turner Syndrome;   Bicuspid Aortic Valve;   Marfan Syndrome
Sponsor:   University of Aarhus
Recruiting - verified June 2015

Triple Chamber Pacing in Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients - TRICHAMPION STUDY

Condition:   Hypertrophic Cardiomyopathy With Obstruction
Intervention:   Device: CRT-P Implant
Sponsor:   St. Jude Medical
Recruiting - verified June 2015

Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis

Condition:   Aortic Stenosis
Intervention:   Procedure: Early surgery
Sponsors:   Asan Medical Center;   Korea Institute of Medicine
Active, not recruiting - verified June 2015

Effects of High Dose Atorvastatin in Patients With Surgical Aortic Stenosis

Conditions:   Aortic Valve Stenosis;   Ventricular Hypertrophy
Intervention:   Drug: Atorvastatin 80 mg
Sponsor:   University Hospital, Strasbourg, France
Recruiting - verified June 2015

Follow Up on Freestyle Valves in Children

Conditions:   Right Ventricle;   Pulmonary Valve Stenosis;   Pulmonary Valve Atresia
Intervention:   Procedure: Echocardiogram
Sponsor:   Emory University
Active, not recruiting - verified June 2015

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