Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Impact of Elastin Mediated Vascular Stiffness on the Brain

Conditions:   Williams Syndrome;   Supravalvular Aortic Stenosis;   Cardiovascular Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified July 2016

Evaluation of the BARD® True™ Flow Valvuloplasty Perfusion Catheter for Aortic Valve Dilatation

Condition:   Aortic Valve Stenosis
Intervention:   Device: True™ Flow Valvuloplasty Perfusion Catheter
Sponsor:   C. R. Bard
Not yet recruiting - verified July 2016

Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Feasibility Trial CANADA

Condition:   Aortic Valve Stenosis
Intervention:   Device: HLT Transcatheter Aortic Valve System
Sponsor:   HLT Inc.
Not yet recruiting - verified July 2016

Reactive Oxygen Species Following Aortic Valve Replacement

Condition:   Aortic Stenosis
Intervention:  
Sponsor:   University Hospital Southampton NHS Foundation Trust.
Recruiting - verified July 2016

TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis

Condition:   Aortic Valve Stenosis
Interventions:   Device: SAPIEN 3;   Procedure: SAVR
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2016

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

Condition:   Cardiomyopathy, Hypertrophic Obstructive
Intervention:   Drug: MYK-461
Sponsor:   MyoKardia, Inc.
Not yet recruiting - verified July 2016

The Medtronic Transcatheter Aortic Valve Implant System (CoreValve System Family) Post Marketing Surveillance (PMS) (CoreValve India PMS)

Condition:   Symptomatic Aortic Stenosis
Intervention:   Device: CoreValve System Family
Sponsors:   Medtronic Cardiovascular;   Medtronic
Recruiting - verified July 2016

The Medtronic TAVR 2.0 US Clinical Study

Condition:   Aortic Valve Stenosis
Intervention:   Device: Medtronic Transcatheter Aortic Valve 2.0 Replacement System
Sponsor:   Medtronic Cardiovascular
Recruiting - verified July 2016

TAVI Without Balloon Predilatation (of the Aortic Valve ) SAPIEN 3

Condition:   Aortic Valve Stenosis
Intervention:   Procedure: TAVI
Sponsors:   University Hospital, Montpellier;   Edwards Lifesciences
Recruiting - verified July 2016

Quality of Life After Ministernotomy Versus Full Sternotomy Aortic Valve Replacement

Conditions:   Aortic Valve Stenosis;   Heart Valve Diseases;   Aortic Valve Disease
Interventions:   Procedure: ministernotomy;   Procedure: Full sternotomy
Sponsor:   Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Recruiting - verified July 2016

Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement

Conditions:   Aortic Valve Disease;   Aortic Stenosis
Interventions:   Device: Perceval valve;   Device: other stented biological valve
Sponsor:   LivaNova
Recruiting - verified July 2016

Assessment of the Prognosis of Persistent Left Bundle Branch Block (LBBB)After Transcatheter Aortic Valve Implantation (TAVI ) by an Electrophysiological and Remote Monitoring Risk-adapted Algorithm

Condition:   Post-TAVI
Interventions:   Other: pacemaker implantation;   Other: holter implantation
Sponsors:   University Hospital, Clermont-Ferrand;   LivaNova;   Biotronik France
Recruiting - verified July 2016

Neuroprotection in Patients Undergoing Aortic Valve Replacement

Conditions:   Aortic Stenosis;   Brain Infarction;   Cerebrovascular Accident;   Stroke
Interventions:   Device: Embol-X Embolic Protection Device;   Device: CardioGard Cannula
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified July 2016

REPRISE Next Generation Delivery System

Condition:   Aortic Stenosis
Intervention:   Device: Lotus Valve and LOTUS Edge Valve System
Sponsor:   Boston Scientific Corporation
Recruiting - verified July 2016

Investigation of Patients With BAV Requiring Valve and/or Aortic Repair (GISSI Outliers VAR)

Conditions:   Bicuspid Aortic Valve;   Aortic Regurgitation;   Aortic Dilatation
Intervention:  
Sponsor:   Gruppo di Ricerca GISSI
Active, not recruiting - verified July 2016

Aortic Valve and Root Measurements Under Real-Time 3-Dimensional Visualization During Angiography

Conditions:   Coronary Artery Disease;   Aortic Stenosis
Intervention:   Radiation: Real-time 3-dimensional DynaCT
Sponsor:   Binita Shah
Recruiting - verified July 2016

International Bicuspid Aortic Valve Consortium (BAVCon)

Conditions:   Bicuspid Aortic Valve Disease;   Thoracic Aortic Disease in Patients With a Bicuspid Aortic Valve
Intervention:  
Sponsor:   Brigham and Women's Hospital
Recruiting - verified July 2016

Cardiac Function After Minimally Invasive Aortic Valve Implantation

Conditions:   Aortic Valve Stenosis;   Heart Valve Diseases
Interventions:   Procedure: Minimally invasive aortic valve replacement;   Procedure: Conventional aortic valve replacement
Sponsors:   Karolinska University Hospital;   Karolinska Institutet
Completed - verified July 2016

Identification of Genetic Mechanisms of Bicuspid Aortic Valve Disease

Condition:   Bicuspid Aortic Valve
Intervention:  
Sponsors:   Brigham and Women's Hospital;   Massachusetts General Hospital
Recruiting - verified July 2016

Logical Analysis of Data and Cardiac Surgery Risk

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Aortic Valve Stenosis;   Mitral Valve Stenosis
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008