Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - PARTNER II - PARTNERII - S3 Intermediate

Condition:   Symptomatic Severe Aortic Stenosis
Intervention:   Device: TAVR
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified July 2017

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - PARTNER II - High Risk and Nested Registry 7

Condition:   Symptomatic Severe Aortic Stenosis
Intervention:   Device: TAVR Implantation of the THV Prosthesis
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified July 2017

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - PARTNER II - Nested Registry 3/Valve-in-Valve

Conditions:   Aortic Stenosis;   Cardiomyopathy, Hypertrophic
Intervention:   Device: Edwards SAPIEN XT transcatheter valve, Model 9300TFX
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified July 2017

Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis

Conditions:   Pulse Wave;   Aortic Stenosis
Interventions:   Other: Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction;   Other: Control group without heart disease
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting - verified July 2017

Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients With AsYmptomatic Severe Aortic Stenosis

Conditions:   Aortic Stenosis;   Heart Diseases
Intervention:   Device: Edwards SAPIEN 3 THV
Sponsor:   Edwards Lifesciences
Not yet recruiting - verified July 2017

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

Condition:   Mitral Valve Failure
Interventions:   Device: Edwards SAPIEN 3 transcatheter heart valve;   Device: ASHI INTECC Astato XS 20
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified May 11, 2017

Efficacy, Safety, and Tolerability of Perhexiline in Subjects With Hypertrophic Cardiomyopathy and Heart Failure

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Perhexiline;   Drug: Placebo
Sponsor:   Heart Metabolics Limited
Withdrawn - verified July 2017

Surgical Trauma After Partial Upper Hemisternotomy Versus Full Sternotomy Aortic Valve Replacement

Conditions:   Aortic Valve Stenosis;   Heart Valve Diseases
Interventions:   Procedure: Minimally invasive aortic valve replacement;   Procedure: Full sternotomy aortic valve replacement
Sponsors:   Karolinska University Hospital;   Karolinska Institutet
Recruiting - verified July 2017

Aortic Valve and Root Measurements Under Real-Time 3-Dimensional Visualization During Angiography

Conditions:   Coronary Artery Disease;   Aortic Stenosis
Intervention:   Radiation: Real-time 3-dimensional DynaCT
Sponsor:   New York University School of Medicine
Completed - verified July 2017

Clinical Trial of the Edwards Aortic Bioprosthesis, Model 11000

Conditions:   Aortic Valve Disorder;   Aortic Valve Insufficiency;   Aortic Valve Stenosis;   Heart Failure;   Coronary Artery Disease
Intervention:   Procedure: Heart Valve Surgery
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified July 2017

Surgical Treatment of Aortic Stenosis With a Next Generation Surgical Aortic Valve

Conditions:   Aortic Valve Stenosis With Insufficiency;   Aortic Valve Stenosis
Intervention:   Device: Aortic Valve Replacement with EDWARDS INTUITY Valve System
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified July 2017

A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease

Condition:   Aortic Valve Disease
Intervention:  
Sponsor:   Baylor Research Institute
Active, not recruiting - verified July 2017

The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome

Conditions:   Velocardiofacial Syndrome;   Williams Syndrome;   Fragile X Syndrome
Intervention:   Drug: methylphenidate, fluoxetin, risperidone
Sponsor:   The Chaim Sheba Medical Center
Recruiting - verified July 2017