Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Impact of Elastin Mediated Vascular Stiffness on the Brain

Conditions:   Williams Syndrome;   Supravalvular Aortic Stenosis;   Cardiovascular Disease
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified July 2016

Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Feasibility Trial CANADA

Condition:   Aortic Valve Stenosis
Intervention:   Device: HLT Transcatheter Aortic Valve System
Sponsor:   HLT Inc.
Not yet recruiting - verified July 2016

Reactive Oxygen Species Following Aortic Valve Replacement

Condition:   Aortic Stenosis
Intervention:  
Sponsor:   University Hospital Southampton NHS Foundation Trust.
Recruiting - verified July 2016

The Plasma Serotonin and Aortic Stenosis: a Pilot Study.

Condition:   Aortic Stenosis
Intervention:   Procedure: biomarkers
Sponsor:   University Hospital, Toulouse
Recruiting - verified July 2016

TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis

Condition:   Aortic Valve Stenosis
Interventions:   Device: SAPIEN 3;   Procedure: SAVR
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2016

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

Condition:   Cardiomyopathy, Hypertrophic Obstructive
Intervention:   Drug: MYK-461
Sponsor:   MyoKardia, Inc.
Not yet recruiting - verified July 2016

Comparison of a Rivaroxaban-based Strategy With an Antiplatelet-based Strategy Following Successful TAVR for the Prevention of Leaflet Thickening and Reduced Leaflet Motion as Evaluated by Four-dimensional, Volume-rendered Computed Tomography (4DCT)

Conditions:   Aortic Valve Stenosis;   Cardiovascular Diseases;   Heart Valve Diseases;   Ventricular Outflow Obstruction;   Thrombosis
Interventions:   Drug: Acetylicsalicylic acid;   Drug: Clopidogrel;   Drug: Rivaroxaban
Sponsors:   ECRI bv;   Rigshospitalet, Denmark;   Bayer;   Cardialysis BV
Recruiting - verified July 2016

TAVI Without Balloon Predilatation (of the Aortic Valve ) SAPIEN 3

Condition:   Aortic Valve Stenosis
Intervention:   Procedure: TAVI
Sponsors:   University Hospital, Montpellier;   Edwards Lifesciences
Recruiting - verified July 2016

Quality of Life After Ministernotomy Versus Full Sternotomy Aortic Valve Replacement

Conditions:   Aortic Valve Stenosis;   Heart Valve Diseases;   Aortic Valve Disease
Interventions:   Procedure: ministernotomy;   Procedure: Full sternotomy
Sponsor:   Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Recruiting - verified July 2016

Neuroprotection in Patients Undergoing Aortic Valve Replacement

Conditions:   Aortic Stenosis;   Brain Infarction;   Cerebrovascular Accident;   Stroke
Interventions:   Device: Embol-X Embolic Protection Device;   Device: CardioGard Cannula
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified July 2016

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Eleclazine;   Drug: Placebo
Sponsor:   Gilead Sciences
Recruiting - verified July 2016

International Bicuspid Aortic Valve Consortium (BAVCon)

Conditions:   Bicuspid Aortic Valve Disease;   Thoracic Aortic Disease in Patients With a Bicuspid Aortic Valve
Intervention:  
Sponsor:   Brigham and Women's Hospital
Recruiting - verified July 2016

Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis

Condition:   Aortic Stenosis
Intervention:   Procedure: Early surgery
Sponsors:   Asan Medical Center;   Korea Institute of Medicine
Active, not recruiting - verified July 2016

Identification of Genetic Mechanisms of Bicuspid Aortic Valve Disease

Condition:   Bicuspid Aortic Valve
Intervention:  
Sponsors:   Brigham and Women's Hospital;   Massachusetts General Hospital
Recruiting - verified July 2016

Logical Analysis of Data and Cardiac Surgery Risk

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Coronary Disease;   Aortic Valve Stenosis;   Mitral Valve Stenosis
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2008