Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

The Safety and Effectiveness of Transcatheter Aortic Valve Raplacemet in Intermediate Risk Patients With Bicuspid Aortic Stenosis

Condition:   Aortic Valve Disease
Interventions:   Procedure: TAVR;   Procedure: SAVR
Sponsor:   China National Center for Cardiovascular Diseases
Not yet recruiting - verified May 2017

Presentations of Hypertrophic Cardiomyopathy on Myocardial Perfusion Imaging

Conditions:   Hypertrophic Cardiomyopathy;   Myocardial Perfusion Imaging
Intervention:   Diagnostic Test: myocardial perfusion imaging
Sponsor:   Far Eastern Memorial Hospital
Recruiting - verified May 2017

Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Intermediate Risk of Mortality

Condition:   Aortic Valve Stenosis
Interventions:   Device: Transcatheter aortic valve implantation;   Procedure: Surgical aortic valve replacement
Sponsors:   Universitätsklinikum Hamburg-Eppendorf;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)
Recruiting - verified May 2017

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

Condition:   Mitral Valve Failure
Interventions:   Device: Edwards SAPIEN 3 transcatheter heart valve;   Device: ASHI INTECC Astato XS 20
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified May 11, 2017

The PARTNER 3 - AVIV Trial

Conditions:   Aortic Stenosis;   Cardiomyopathy, Hypertrophic
Intervention:   Device: Edwards SAPIEN 3 transcatheter valve, Model 9600TFX
Sponsor:   Edwards Lifesciences
Recruiting - verified April 2017


Condition:   Aortic Valve Stenosis
Intervention:   Device: 29 mm LOTUS Edge™ Valve System
Sponsor:   Boston Scientific Corporation
Not yet recruiting - verified May 2017

Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly

Conditions:   Cognitive Decline;   Stroke
Sponsor:   University Hospital, Lille
Recruiting - verified May 2017

Reactive Oxygen Species Following Aortic Valve Replacement

Condition:   Aortic Stenosis
Sponsor:   University Hospital Southampton NHS Foundation Trust
Recruiting - verified May 2017

Assessment of Wall Thickness in Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Procedure: Noncontrast echocardiography;   Procedure: Contrast Echocardiography;   Procedure: Cardiac magnetic resonance imaging
Sponsors:   Mayo Clinic;   GE Healthcare
Recruiting - verified May 2017

Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve

Conditions:   Aortic Valve Stenosis;   Aortic Valve Stenosis With Insufficiency;   Regurgitation, Aortic Valve;   Aortic Valve Incompetence
Intervention:   Device: EDWARDS INTUITY valve
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified May 2017

The Nordic Aortic Valve Intervention Trial

Condition:   Critical Aortic Stenosis
Interventions:   Procedure: Transcatheter Aortic Valve Implantation;   Procedure: Surgical Aortic Valve Replacement
Sponsors:   Rigshospitalet, Denmark;   Odense University Hospital;   Sahlgrenska University Hospital, Sweden;   Danish Heart Foundation;   Copenhagen Trial Unit, Center for Clinical Intervention Research
Active, not recruiting - verified May 2017