Angina

Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

The Evaluation and Management of Patients With Acute Chest Pain in China

Conditions:   Acute Chest Pain;   Acute Coronary Syndrome
Intervention:  
Sponsors:   Yuguo Chen;   People's Hospital of Jinxiang County;   People's Hospital of Chengwu;   Traditional Chinese Medicine Hospital of Wucheng County;   People's Hospital of Longkou City;   People's Hospital of Gaomi City;   People's Hospital of Yishui County, Linyi City;   People's Hospital of Wenshang County;   The 2nd People's Hospital of Liaocheng City;   People's Hospital of Shouguang City;   Traditional Chinese Medicine Hospital of Pingyin County;   Traditional Chinese Medicine Hospital of Laoling City;   The 2nd People's Hospital of Dongying City;   Affiliated Hospital of Shandong Academy of Medical Sciences;   People's Hospital of Shizhong District, Jinan City;   The 2nd People's Hospital of Dezhou City;   Central Hospital of Zibo City;   Jining Medical University;   People's Hospital of Mudan, Heze City;   The 3rd People's Hospital of Jinan City;   Qianfoshan Hospital of Shandong Province;   Xinlongzhuang Colliery Hospital;   The 2nd Traditional Chinese Medicine Hospital of Taian City
Not yet recruiting - verified August 2015

Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery

Conditions:   Hypotension;   Postoperative Complications;   Acute Coronary Syndrome;   Heart Failure;   Coronary Occlusion;   Stroke;   Acute Kidney Injury;   Renal Insufficiency, Chronic;   Death
Interventions:   Drug: Liberal blood pressure management;   Drug: Tight blood pressure management
Sponsor:   Miodrag Filipovic, Prof. Dr. med.
Not yet recruiting - verified August 2015

Attentional Capacity and Working Memory in Coronary Artery Disease Patients: Impact of the Presence of a Sleep Apnea Syndrome and Chronic Effects of Treatment With CPAP

Conditions:   Obstructive Sleep Apnea;   Acute Coronary Syndrome
Intervention:   Device: CPAP treatment
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting - verified August 2015

A Trial Evaluating Methods to Use Physical Activity to Improve Outcomes After Hospitalization for Acute Coronary Syndrome

Conditions:   Physical Activity;   Acute Coronary Syndrome
Interventions:   Behavioral: Financial-incentive based physical activity program;   Device: "Misfit Shine" Wearable Activity Tracking Device
Sponsor:   University of Pennsylvania
Not yet recruiting - verified August 2015

Comparison of Ticagrelor vs. Prasugrel on Inflammation, Arterial Stiffness, Endothelial Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Coronary Stenting

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Ticagrelor;   Drug: Prasugrel
Sponsors:   Korea University Anam Hospital;   AstraZeneca
Recruiting - verified August 2015

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Recruiting - verified August 2015

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Recruiting - verified August 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural Medical University ;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified August 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified September 2015

An Observational Prospective Study to Understand the Usage Pattern of Ticagrelor With ACS (Acute Coronary Syndrome)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study

Condition:   Cost Sharing, Acute Coronary Syndrome,
Intervention:   Other: Study voucher card
Sponsors:   AstraZeneca;   Duke Clinical Research Institute
Recruiting - verified September 2015

Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds (OPreNBiS)

Conditions:   Coronary Artery Disease;   Angina;   Unstable Angina;   Stable Angina
Interventions:   Device: Predilatation with OPN NC balloon catheter.;   Device: Predilatation with standard compliant balloon.;   Device: Absorb BVS implantation.;   Procedure: Treated segment visualization by OCT.;   Other: Clinical FU at 12 months.
Sponsor:   SIS Medical AG
Recruiting - verified August 2015

Benefits of Exercise Training in Women With Ischemic Syndrome

Condition:   Microvascular Coronary Dysfunction
Intervention:   Behavioral: Exercise training
Sponsor:   Cedars-Sinai Medical Center
Not yet recruiting - verified August 2015

Chest Pain Perception and Capsaicin Sensitivity

Condition:   Chest Pain
Intervention:   Drug: Capsaicin
Sponsor:   Bassett Healthcare
Active, not recruiting - verified August 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Improvement of Subjective Well-Being by Ranolazine Among Unrevascularized Chronic Stable Coronary Artery Disease Patients

Condition:   Angina
Interventions:   Drug: Ranolazine;   Drug: Sugar pill
Sponsors:   North Florida Foundation for Research and Education;   Gilead Sciences
Recruiting - verified August 2015

Magnetic Resonance Imaging for Global Atherosclerosis Risk Assessment

Conditions:   Cardiovascular Disease;   Atherosclerosis
Interventions:   Other: MRI;   Other: PET/MRI;   Other: Laboratory blood test
Sponsor:   Cedars-Sinai Medical Center
Recruiting - verified August 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Study Of Costs Realized After Percutaneous Coronary intervenTion Employing Same Day Discharge

Condition:   Coronary Artery Disease
Intervention:   Procedure: Same day discharge
Sponsors:   Saint Joseph Mercy Health System;   Michigan Heart;   Blue Cross Blue Shield of Michigan Foundation
Terminated - verified August 2015

Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.

Condition:   Acute Coronary Syndrome
Interventions:   Drug: MEOPA and paracetamol;   Drug: Morphine
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2015

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Losmapimod 7.5 mg twice daily;   Drug: Placebo twice daily
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Recruiting - verified August 2015

Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Intervention:   Other: blood sample
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified August 2015

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   The Cleveland Clinic
Recruiting - verified August 2015

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Treatment 90 days DAPT;   Drug: Treatment 360 days DAPT
Sponsor:   Diagram B.V.
Recruiting - verified August 2015

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)

Conditions:   Hypertension;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified August 2015

Use of Abbott High Sensitivity Troponin I Assay In Acute Coronary Syndromes

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction;   Troponin
Intervention:  
Sponsors:   Minneapolis Medical Research Foundation;   Abbott Diagnostics Division;   Hennepin County Medical Center, Minneapolis
Active, not recruiting - verified August 2015

Aspirin Impact on Platelet Reactivity in Acute Coronary Syndrome Patients on Novel P2Y12 Inhibitors Therapy

Conditions:   Acute Coronary Syndrome;   Platelet Function and Reactivity Tests;   Novel P2Y12 Inhibitors
Intervention:   Drug: Aspirin
Sponsor:   Sheba Medical Center
Recruiting - verified August 2015

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified September 2015

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

Condition:   Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Withdrawn - verified September 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

TAKO-TSUBO Cardiomyopathy and Genetic

Conditions:   Tako-TSUBO Cardiomyopathy;   Acute Coronary Syndrome
Intervention:  
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Fédération Française de Cardiologie
Active, not recruiting - verified August 2015

Kansai Plus Atrial Fibrillation Trial

Condition:   Atrial Fibrillation
Interventions:   Procedure: ATP guide additional ablation.;   Drug: Antiarrhythmic drug (AAD);   Procedure: ATP guide additional ablation.;   Drug: Control;   Procedure: Control;   Drug: Antiarrhythmic drug (AAD);   Procedure: Control;   Drug: Control
Sponsor:   Kyoto University, Graduate School of Medicine
Active, not recruiting - verified August 2015

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Condition:   Crohn's Disease
Interventions:   Drug: CP-690,550;   Drug: CP-690,550
Sponsor:   Pfizer
Recruiting - verified August 2015

Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain

Conditions:   Chest Pain;   Angina;   Angina Pectoris;   Coronary Artery Disease
Interventions:   Procedure: Stress Echocardiography;   Procedure: Coronary CT Angiography
Sponsors:   Montefiore Medical Center;   American Heart Association
Recruiting - verified August 2015

A Study of RoActemra/Actemra (Tocilizumab) in Comparison to Etanercept in Patients With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Condition:   Cardiovascular Disease, Rheumatoid Arthritis
Interventions:   Drug: etanercept;   Drug: tocilizumab [RoActemra/Actemra]
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified September 2015

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified September 2015

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified September 2015

Effects of Telmisartan on Ischemic Cardiovascular Events in High-risk Hypertensive Patients

Conditions:   Acute Myocardial Infarction;   Angina Pectoris;   Myocardial Ischemia;   Acute Coronary Syndrome;   Hypertension
Interventions:   Drug: Micardis (Telmisartan);   Drug: Blopress (Candesartan)
Sponsor:   Kyoto Prefectural University of Medicine
Terminated - verified September 2015

Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina;   Acute Coronary Syndrome
Interventions:   Procedure: Coronary Computed Tomography Angiography;   Procedure: Stress Nuclear Myocardial Perfusion Imaging
Sponsors:   Montefiore Medical Center;   American Heart Association;   Albert Einstein College of Medicine of Yeshiva University
Completed - verified August 2015

Thiazolidinediones Or Sulphonylureas and Cardiovascular Accidents.Intervention Trial

Conditions:   Type 2 Diabetes Mellitus;   Cardiovascular Disease
Interventions:   Drug: add-on pioglitazone;   Drug: add-on sulphonylurea
Sponsors:   Italian Society of Diabetology;   Associazione Medici Diabetologi (AMD);   Associazione Nazionale Medici Cardiologi Ospedalieri
Active, not recruiting - verified August 2015

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Condition:   Coronary Heart Disease
Interventions:   Drug: Evidence-based medical care for Acute Coronary Syndrome;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified September 2015

Effects of Disease Management on Development of End Stage Renal Disease in Type 2 Diabetic Patients With Nephropathy

Conditions:   Type 2 Diabetes Mellitus;   DM Nephropathy
Intervention:   Behavioral: Multidisciplinary team care
Sponsor:   Chinese University of Hong Kong
Completed - verified August 2015

EARLY ACS: Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-segment Elevation Acute Coronary Syndrome (Study P03684AM2)(COMPLETED)

Conditions:   Myocardial Ischemia;   Acute Coronary Syndrome
Interventions:   Drug: Eptifibatide (Integrilin);   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Duke Clinical Research Institute
Completed - verified September 2015

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