Angina

Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Ivabradine and Post-revascularisation Microcirculatory Dysfunction

Conditions:   Coronary Artery Disease;   Angina
Intervention:   Drug: Ivabradine
Sponsor:   Liverpool Heart and Chest Hospital NHS Foundation Trust
Not yet recruiting - verified July 2015

Bioresorbable Polymer ORSIRO Versus Durable Polymer RESOLUTE ONYX Stents

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina Pectoris;   Acute Coronary Syndrome;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Orsiro;   Device: Resolute Onyx
Sponsor:   Thorax Centrum Twente
Not yet recruiting - verified July 2015

Stavanger UncomPlicatEd Elective PCI Same DaY Discharge Study (SPEEDY Study)

Condition:   Coronary Artery Disease
Intervention:   Procedure: same day discharge
Sponsor:   Helse Stavanger HF
Not yet recruiting - verified July 2015

Assessment of Prospective CYP2C19 Genotype Guided Dosing of Anti-Platelet Therapy in Percutaneous Coronary Intervention

Conditions:   Acute Coronary Syndrome;   Cardiovascular Diseases
Intervention:   Genetic: CYP2C19 genotyping
Sponsor:   University of Pennsylvania
Recruiting - verified July 2015

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Not yet recruiting - verified July 2015

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Recruiting - verified July 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural Medical University ;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified July 2015

An Observational Prospective Study to Understand the Usage Pattern of Ticagrelor With ACS (Acute Coronary Syndrome)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Sub Lingual Versus Traditional Oral Administration of Ticagrelor in Acute Coronary Syndrome/Non ST-elevation Myocardial Infarction - A Platelet Reactivity Study

Conditions:   Acute Coronary Syndromes;   Non ST Elevation Myocardial Infarction
Intervention:   Drug: Sub Lingual Ticagrelor
Sponsor:   Sheba Medical Center
Recruiting - verified July 2015

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Harvard Clinical Research Institute;   Medstar Research Institute
Recruiting - verified June 2015

Clinical Study Protocol - Debris Interventional Removal in ACS (DESIRE-ACS)

Conditions:   Coronary Disease;   Acute Coronary Syndrome;   Coronary Occlusion
Intervention:   Device: Bell Balloon Catheter
Sponsor:   Angioslide Ltd.
Recruiting - verified July 2015

The Preventive Implantation of Bioresorbable Vascular Scaffold on Functionally Insignificant Stenosis With Vulnerable Plaque Characteristics

Conditions:   Coronary Artery Disease;   Plaque, Atherosclerotic
Interventions:   Device: Bioresorbable Vascular Scaffold;   Drug: Optimal Medical treatment
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2015

CCC Project- Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   Beijing Institute of Heart, Lung and Blood Vessel Diseases;   American Heart Association;   Chinese Society of Cardiology
Recruiting - verified July 2015

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified July 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Long-term Follow-up of antithrombotIc Management Patterns in Acute Coronary Syndrome Patients in Asia-China Extension

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Exercise as a Life-long Medicine in Patients With Coronary Artery Disease

Conditions:   Cardiovascular Diseases;   Myocardial Infarction;   Angina (Stable)
Interventions:   Behavioral: high-intensity exercise training;   Behavioral: web-based follow-up program;   Behavioral: usual care
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital;   Levanger Hospital
Recruiting - verified July 2015

Randomized Comparison of Radiological Exposure With TRIPTable® in Patients With Acute Coronary Syndromes

Conditions:   Acute Coronary Syndromes;   Angioplasty, Transluminal, Percutaneous Coronary
Interventions:   Device: TripTable;   Device: Radial;   Device: Femoral
Sponsor:   Marilia Medicine School
Active, not recruiting - verified July 2015

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   The Cleveland Clinic
Recruiting - verified July 2015

HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt

Conditions:   Coronary Arteriosclerosis;   Non ST Segment Elevation Acute Coronary Syndrome
Interventions:   Device: OrbusNeich Combo stent™;   Device: Everolimus Eluting Stent (EES)
Sponsors:   OrbusNeich;   OrbusNeich Medical K.K.;   Duke Clinical Research Institute
Recruiting - verified July 2015

Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis

Condition:   Saphenous Vein Graft Disease
Interventions:   Drug: Aspirin;   Drug: Ticagrelor
Sponsors:   Boca Raton Regional Hospital;   AstraZeneca
Recruiting - verified July 2015

Safety & Efficacy of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia (ATHENA II)

Condition:   Myocardial Ischemia
Interventions:   Device: Celution System;   Device: Placebo
Sponsor:   Cytori Therapeutics
Active, not recruiting - verified December 2014

Cardiovascular Outcomes Following Treatment With Ertugliflozin in Participants With Type 2 Diabetes Mellitus and Established Vascular Disease (MK-8835-004)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Active, not recruiting - verified July 2015

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

Cardiology-Emergency Medicine Cardiac Biomarker Research Initiative

Condition:   Acute Coronary Syndrome
Intervention:   Other: OBSERVATIONAL REGISTRY
Sponsor:   Henry Ford Health System
Completed - verified July 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Brilinta DaYu Study

Condition:   Acute Coronary Syndrome
Intervention:   Drug: Ticagrelor
Sponsor:   AstraZeneca
Active, not recruiting - verified July 2015

Screening for Abdominal Aortic Aneurysm Using a Portable Transthoracic Echocardiography Among Patients With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   HaEmek Medical Center, Israel
Recruiting - verified July 2015

Cardiogenesis Transmyocardial Revascularization Registry

Condition:   Class IV Angina
Intervention:  
Sponsor:   Cardiogenesis Corporation, a wholly-owned subsidiary of CryoLife, Inc.
Completed - verified July 2015

GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation

Condition:   Coronary Artery Disease (CAD)
Interventions:   Drug: Ticagrelor;   Drug: Acetylsalicylic Acid;   Drug: Clopidogrel
Sponsors:   ECRI bv;   Biosensors International;   AstraZeneca;   The Medicines Company
Recruiting - verified July 2015

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Cardiac Valve Disease
Interventions:   Device: SternaLock Blue closure system;   Device: Suture Wire
Sponsor:   Biomet, Inc.
Active, not recruiting - verified July 2015

A Study to Assess Cardiovascular Outcomes Following Treatment With MK-3102 in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: MK-3102;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified July 2015

Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)

Conditions:   Acute Coronary Syndrome;   Angina Pectoris;   Angina, Unstable;   Myocardial Infarction;   Coronary Artery Disease;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Orsiro;   Device: Synergy;   Device: Resolute Integrity
Sponsor:   Cardio Research Enschede BV
Enrolling by invitation - verified July 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes

Conditions:   Coronary Artery Disease;   Diabetes Mellitus, Type 2
Interventions:   Drug: Liraglutide;   Drug: Placebo
Sponsor:   Haugaard, Steen Bendix, M.D., DMSc
Completed - verified July 2015

A Study to Evaluate Cardiovascular Outcomes in Patients With Type 2 Diabetes Treated With ITCA 650

Condition:   Type 2 Diabetes
Interventions:   Drug: ITCA 650;   Other: ITCA placebo
Sponsor:   Intarcia Therapeutics
Active, not recruiting - verified July 2015

DUrable Polymer-based STent CHallenge of Promus Element Versus ReSolute Integrity in an All Comers Population

Conditions:   Acute Coronary Syndrome;   Angina Pectoris;   Angina, Unstable;   Myocardial Infarction;   Coronary Artery Disease;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Resolute Integrity (Zotarolimus-eluting stent);   Device: Promus Element (Everolimus-eluting stent)
Sponsor:   Cardio Research Enschede BV
Completed - verified July 2015

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Conditions:   Atherosclerosis;   Hypercholesterolemia
Interventions:   Drug: Statin Drugs;   Other: HMG-CoA Reductase Inhibitors
Sponsor:   National Institutes of Health Clinical Center (CC)
Active, not recruiting - verified April 2015

The Real-World Endeavor Resolute Versus XIENCE V Drug-Eluting Stent Study in Twente

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina Pectoris;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Endeavor Resolute (Biolinx-based Zotarolimus-eluting stent);   Device: Xience V (Everolimus-eluting stent)
Sponsor:   Cardio Research Enschede BV
Completed - verified July 2015

Endothelial Function and Heart Rate Variability After Stenting

Condition:   Restenosis or Adverse Cardiovascular Event
Intervention:   Device: stent implantation in coronary artery
Sponsor:   Helse Stavanger HF
Completed - verified October 2009

Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department

Conditions:   Acute Myocardial Infarction;   Chest Pain;   Acute Coronary Syndrome
Intervention:  
Sponsor:   Biosite
Withdrawn - verified July 2015

Rapid Assessment of Cardiac Markers for the Evaluation of Acute Coronary Syndrome (RACE-ACS)

Condition:   Acute Coronary Syndrome
Intervention:   Device: Triage CardioProfilER (Troponin I, Myoglobin, CK-MB, BNP)
Sponsor:   Biosite
Withdrawn - verified July 2015

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