Angina

Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

The TRUST Trial - CardioVascular Imaging ECHO

Conditions:   Thyroid Dysfunction;   Atherosclerosis;   Heart Failure
Interventions:   Drug: Levothyroxine;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   University of Lausanne Hospitals;   University Hospital, Geneva
Recruiting - verified July 2016

The TRUST Study - CardioVascular Imaging IMT

Conditions:   Thyroid Dysfunction;   Atherosclerosis;   Heart Failure
Interventions:   Drug: Levothyroxine;   Drug: Placebo
Sponsors:   University Hospital Inselspital, Berne;   University of Lausanne Hospitals;   University Hospital, Geneva
Recruiting - verified July 2016

Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years

Condition:   Chest Pain in Extremely Critical Condition
Intervention:  
Sponsor:   Qilu Hospital
Recruiting - verified July 2016

3-Month Discontinuation of Dual Antiplatelet Therapy After Ultimaster Sirolimus-Eluting Stent Implantation

Condition:   Coronary Artery Disease
Interventions:   Drug: Aspirin;   Drug: Thienopyridine
Sponsor:   Teikyo University
Not yet recruiting - verified July 2016

Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Metallic Stents for Diffuse Long Coronary Artery Disease

Condition:   Percutaneous Transluminal Coronary Angioplasty
Interventions:   Device: everolimus-eluting bioresorbable vascular (Absorb) scaffold;   Device: everolimus-eluting cobalt-chromium (Xience) stent
Sponsors:   Duk-Woo Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified July 2016

PPI's and SSRI's Therapy for the Management of NCCP

Condition:   Chest Pain Rule Out Myocardial Infarction
Intervention:   Drug: Citalopram
Sponsor:   Evangelismos Hospital
Recruiting - verified July 2016

Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention

Conditions:   Radial Artery Spasm;   Angina;   Coronary Artery Disease
Interventions:   Drug: Topical Nitroglycerine;   Drug: Topical Lidocaine
Sponsor:   Aultman Health Foundation
Not yet recruiting - verified July 2016

The Effect of Remote Ischemic Preconditioning on Major Organ Function in Patients With Coronary Artery Disease Undergoing Orthopedic Surgery

Conditions:   Angina Pectoris;   Myocardial Infarction
Interventions:   Procedure: Remote ischemic preconditioning;   Procedure: Sham control
Sponsor:   Seoul National University Hospital
Recruiting - verified July 2016

Self-apposing Stentys Stents Registry

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Azienda Ospedaliera Città della Salute e della Scienza di Torino
Not yet recruiting - verified July 2016

A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Not yet recruiting - verified May 2016

Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients With InteRmediate Stenosis

Condition:   Stable Angina
Intervention:   Device: Drug-eluting stent
Sponsors:   Seoul National University Hospital;   Ajou University School of Medicine;   Keimyung University Dongsan Medical Center;   Inje University
Recruiting - verified July 2016

Comparative Effectiveness of Decision Aids for Stable Chest Discomfort

Conditions:   Coronary Artery Disease;   Stable Angina
Interventions:   Behavioral: Online decision aid;   Behavioral: Video decision aid
Sponsor:   Massachusetts General Hospital
Active, not recruiting - verified July 2016

Remote Ischaemic Conditioning and Coronary Endothelial Function (RIC-COR)

Conditions:   Ischemic Preconditioning;   Coronary Disease
Interventions:   Procedure: Remote ischaemic conditioning;   Procedure: Arm cuff placement, no inflation;
Sponsors:   NHS National Waiting Times Centre Board;   University of Glasgow;   Chest, Heart and Stroke Association Scotland;   Chief Scientist Office of the Scottish Government
Completed - verified July 2016

Vericiguat Drug-drug Interaction With Nitroglycerin in Stable Coronary Artery Disease Patients

Condition:   Coronary Artery Disease
Interventions:   Drug: Vericiguat (BAY1021189);   Drug: Placebo;   Drug: Nitroglycerin
Sponsors:   Bayer;   Merck Sharp & Dohme Corp.
Recruiting - verified July 2016

Treadmill CV Safety Study

Condition:   Stable Angina
Interventions:   Drug: AMG 334;   Drug: Placebo
Sponsor:   Amgen
Recruiting - verified July 2016

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Harvard Clinical Research Institute;   Medstar Research Institute
Active, not recruiting - verified July 2016

Validation of Simple Acute Coronary Syndrome (SACS) Score

Conditions:   Chest Pain;   Acute Coronary Syndrome;   Angina;   Myocardial Infarction
Intervention:  
Sponsors:   Bayfront Health St Petersburg;   Bayfront Health Dade City;   Community Health Systems (CHS)
Enrolling by invitation - verified July 2016

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified July 2016

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Eleclazine;   Drug: Placebo
Sponsor:   Gilead Sciences
Recruiting - verified July 2016

REPARA Study: REgistry of PAtients With bioResorbable Device in Daily Clinical prActice

Condition:   Coronary Artery Lesions With Implantation of Coronary Device
Intervention:  
Sponsor:   Sección Hemodinamica y Cardiologia Intervencionista
Active, not recruiting - verified July 2016

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)

Conditions:   Hypertension;   Cardiovascular Disease
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting - verified July 2016

Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis

Condition:   Saphenous Vein Graft Disease
Interventions:   Drug: Aspirin;   Drug: Ticagrelor
Sponsors:   Boca Raton Regional Hospital;   AstraZeneca;   Ottawa Heart Institute Research Corporation
Recruiting - verified July 2016

Verification of the Safety of Early Discharge in Patients After Acute ST-segment Myocardial Infarction

Conditions:   Coronary Artery Disease;   Acute Myocardial Infarction With ST-segment Elevation;   Primary Percutaneous Coronary Intervention;   Early Discharge
Interventions:   Other: Early discharge;   Other: Standard discharge
Sponsor:   Kamil Novobílský
Recruiting - verified July 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2016

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified July 2016

Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients With Non ST Elevation Elevation Acute Coronary Syndrome

Conditions:   Non ST Elevation Myocardial Infarction;   Unstable Angina
Intervention:   Procedure: Invasive management
Sponsors:   NHS National Waiting Times Centre Board;   University of Glasgow
Completed - verified July 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified July 2016

Fractional Flow Reserve Versus Angiographically Guided Management to Optimise Outcomes in Unstable Coronary Syndromes

Conditions:   Non-ST Elevation Myocardial Infarction.;   Type 1 Myocardial Infarction.
Intervention:   Device: Fractional flow reserve
Sponsors:   NHS National Waiting Times Centre Board;   British Heart Foundation;   St. Jude Medical;   University of Glasgow
Active, not recruiting - verified July 2016

A Study of Evacetrapib in High-Risk Vascular Disease

Condition:   Cardiovascular Diseases
Interventions:   Drug: Evacetrapib;   Drug: Placebo
Sponsors:   Eli Lilly and Company;   The Cleveland Clinic
Active, not recruiting - verified July 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: Placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified July 2016

BIOHELIX-I Bare Metal Stent Study

Condition:   Coronary Arteries Disease
Intervention:   Device: PRO-Kinetic Energy Stent
Sponsor:   Biotronik, Inc.
Active, not recruiting - verified July 2016

PRevention of End Stage Kidney Disease by Darbepoetin Alfa In Chronic Kidney Disease Patients With nondiabeTic Kidney Disease

Conditions:   Chronic Kidney Disease;   Diabetes
Intervention:   Drug: Darbepoetin alfa
Sponsors:   Translational Research Informatics Center, Kobe, Hyogo, Japan;   Showa University School of Medicine
Active, not recruiting - verified July 2016

Acute Coronary Syndrome and Care-Seeking Delay: A Web Based Behavioral Study

Conditions:   Acute Myocardial Infarction;   Heart Attack;   Acute Coronary Syndrome;   Unstable Angina
Intervention:  
Sponsors:   Yale University;   Ohio State University
Completed - verified July 2016

Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Comorbidities

Condition:   Cardiovascular Disease
Interventions:   Drug: Febuxostat;   Drug: Allopurinol
Sponsors:   Takeda;   Teijin America, Inc.
Recruiting - verified July 2016

Post-authorization Safety Study of Etoricoxib and Other Anti-inflammatory Therapies in European Patients With Ankylosing Spondylitis (MK-0663-163)

Condition:   Ankylosing Spondylitis
Intervention:  
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified July 2016

Clinical Trial for Dose Finding and Safety of RVX000222 in Subjects With Stable Coronary Artery Disease

Conditions:   Atherosclerosis;   Coronary Artery Disease
Interventions:   Drug: RVX000222;   Drug: Placebo
Sponsor:   Resverlogix Corp
Completed - verified July 2016

Cardiology Biobank Registry

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   Emory University
Recruiting - verified July 2016

Non-invasive Diagnosis of Coronary Artery Stenoses by Doppler Echocardiography

Conditions:   Stable Angina Pectoris;   Unstable Angina Pectoris;   Acute Myocardial Infarction
Intervention:   Procedure: Doppler echocardiography
Sponsor:   Norwegian University of Science and Technology
Completed - verified July 2016

Effect of Increased Oxygenation in the Air During Endurance Training in Stable Angina Pectoris Patients

Condition:   Angina Pectoris
Interventions:   Behavioral: Hypoxic interval training;   Behavioral: Normoxic interval training
Sponsors:   Norwegian University of Science and Technology;   Aarhus University Hospital
Completed - verified July 2016