Angina

Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Efficacy and Safety of Xuesaitong Soft Capsule for Coronary Heart Disease Unstable Angina

Conditions:   Coronary Heart Disease;   Unstable Angina
Interventions:   Drug: Xuesaitong soft capsule;   Drug: Placebo oral capsule
Sponsor:   Jie Wang
Recruiting - verified March 2017

To Evaluate Safety and Efficacy of CGBIO Stent Compared to Biomatrix Flex Stent in Patients Undergoing Drug-eluting Stent Procedure After Coronary Angiography

Conditions:   Ischemic Heart Disease;   Stable Coronary Artery Disease;   Stable Angina;   Unstable Angina;   NSTEMI - Non-ST Segment Elevation MI
Interventions:   Device: CGBio stent;   Device: Biomatrix flex
Sponsor:   CGBio Inc.
Recruiting - verified March 2017

Physiologic Assessment of Coronary Stenosis Following PCI

Conditions:   Coronary Artery Disease;   Coronary Stenosis;   Angina, Unstable;   Angina, Stable
Intervention:   Diagnostic Test: iFR pullback
Sponsors:   Volcano Corporation;   Duke Clinical Research Institute;   Cardiovascular Research Foundation, New York
Not yet recruiting - verified March 2017

Hybrid Coronary Revascularization Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: Left Internal Mammary Artery (LIMA) to LAD;   Procedure: PCI with metallic DES of non-LAD vessel(s);   Procedure: Percutaneous Coronary Intervention
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified March 2017

Effect of Amlodipine Versus Amlodipine Combined With Atorvastatin on the Coronary Vasospastic Angina

Condition:   Quality of Life
Interventions:   Drug: Caduet 10Mg-20Mg Tablet;   Drug: NorvasC® 10 mg Tablets
Sponsor:   Kosin University Gospel Hospital
Not yet recruiting - verified March 2017

Routine Or Selective Stress Testing After Revascularization: ROSSTAR Trial RCT Outline

Conditions:   Coronary Heart Disease;   Coronary Artery Disease
Interventions:   Other: Observation;   Diagnostic Test: Nuclear Perfusion Imaging Stress Test
Sponsor:   Sir Mortimer B. Davis - Jewish General Hospital
Not yet recruiting - verified March 2017

Metabolomic Profile of Patients Undergoing Myocardial Perfusion SPECT

Condition:   Ischemic Heart Disease
Intervention:   Other: Non intervention
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Recruiting - verified March 2017

Ad5FGF-4 In Patients With Refractory Angina Due to Myocardial Ischemia

Condition:   Angina, Stable
Interventions:   Biological: Ad5FGF-4;   Biological: Placebo
Sponsors:   Angionetics Inc.;   Huapont Life Sciences
Not yet recruiting - verified March 2017

Mindfulness & Stress Management Study for Cardiac Patients

Conditions:   Heart Diseases;   Heart Failure;   Myocardial Infarction;   Chronic Stable Angina;   Coronary Artery Bypass;   Angioplasty
Intervention:   Behavioral: Mindfulness-Based Stress Reduction (MBSR).
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Fairview Health Services
Active, not recruiting - verified March 2017

Feasibility and Outcomes of Complete Coronary Revascularization Using BVS in All-comer Patients With Angina

Condition:   Angina
Intervention:   Device: Bioresorbable vascular scaffold (BVS) implantation
Sponsors:   International Foundation for Development of Medical Science and Education Healthy Heart;   KCRI
Recruiting - verified September 2016

A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Recruiting - verified March 2017

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Active, not recruiting - verified March 2017

Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds (OPreNBiS)

Conditions:   Coronary Artery Disease;   Angina;   Unstable Angina;   Stable Angina
Interventions:   Device: Predilatation with OPN NC balloon catheter.;   Device: Predilatation with standard compliant balloon.;   Device: Absorb BVS implantation.;   Procedure: Treated segment visualization by OCT.;   Other: Clinical FU at 12 months.
Sponsor:   SIS Medical AG
Recruiting - verified September 2016

Study of Ranolazine in Myotonia Congenita, Paramyotonia Congenita and Myotonic Dystrophy Type 1

Conditions:   Myotonia Congenita (Enrollment Complete);   Paramyotonia Congenita;   Myotonic Dystrophy 1
Intervention:   Drug: Ranolazine
Sponsors:   Ohio State University;   Gilead Sciences
Recruiting - verified March 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified March 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Placebo
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified March 2017

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute;   Janssen Research & Development, LLC
Recruiting - verified March 2017

Assessment of Patients With Suspected Coronary Artery Disease (CAD): What is the Best Initial Imaging Strategy?

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   Harald Becher;   Alberta Health Services;   University of Alberta
Completed - verified March 2017

Coronary Hybrid Revascularisation Study

Condition:   Significant Coronary Artery Disease
Intervention:   Procedure: Combined CABG and PCI
Sponsor:   Aarhus University Hospital Skejby
Active, not recruiting - verified March 2017

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Conditions:   Adenovirus;   Adrenal Insufficiency;   Airway Swelling;   Anesthesia;   Anxiety;   Anxiolysis;   Autism;   Autistic Disorder;   Bacterial Meningitis;   Bacterial Septicemia;   Benzodiazepine;   Bipolar Disorder;   Bone and Joint Infections;   Brain Swelling;   Central Nervous System Infections;   Convulsions;   Cytomegalovirus Retinitis;   Early-onset Schizophrenia Spectrum Disorders;   Edema;   Epilepsy;   General Anesthesia;   Gynecologic Infections;   Headaches;   Herpes Simplex Virus;   Hypertension;   Infantile Hemangioma;   Infection;   Inflammation;   Inflammatory Conditions;   Influenza;   Intra-abdominal Infections;   Lower Respiratory Tract Infections;   Migraines;   Pain;   Pneumonia;   Prophylaxis;   Schizophrenia;   Sedation;   Seizures;   Skeletal Muscle Spasms;   Skin and Skin-structure Infections;   Stable Angina;   Thromboprophylaxis;   Thrombosis;   Treatment-resistant Schizophrenia;   Urinary Tract Infection;   Withdrawal
Intervention:   Drug: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
Sponsors:   Daniel Benjamin;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   The EMMES Corporation;   OpAns, LLC
Recruiting - verified March 2017

Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain

Conditions:   Chest Pain;   Angina;   Angina Pectoris;   Coronary Artery Disease
Interventions:   Procedure: Stress Echocardiography;   Procedure: Coronary CT Angiography
Sponsors:   Montefiore Medical Center;   American Heart Association
Completed - verified March 2017

Cardiogoniometry for Early Diagnosis of Coronary Artery Disease Symptomatik

Condition:   Stable Angina Pectoris
Intervention:   Procedure: cardiogoniometry
Sponsor:   Stiftung Institut fuer Herzinfarktforschung
Completed - verified August 2010

Evaluation of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: follow-up coronary angiography;   Procedure: Clinical follow-up
Sponsor:   Takeshi Morimoto
Completed - verified March 2017

The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Darapladib 160 mg;   Drug: Placebo;   Other: Standard Therapy
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Completed - verified March 2017

Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: fondaparinux background and standard dose UFH;   Drug: Fondaparinux background and low dose heparin;   Drug: Open label fondaparinux
Sponsor:   GlaxoSmithKline
Completed - verified March 2017

The Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy Trial

Condition:   Atherosclerosis
Interventions:   Drug: Darapladib;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed - verified March 2017