Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

CORonary MICrovascular Angina (CorMicA)

Conditions:   Angina, Stable;   Coronary Vasospasm;   Coronary Circulation;   Coronary Syndrome;   Microvascular Angina;   Coronary Disease
Intervention:   Diagnostic Test: Stratified medicine involving a diagnostic intervention
Sponsors:   NHS National Waiting Times Centre Board;   British Heart Foundation
Recruiting - verified June 2017

Downstream Molecular Signals of P2Y12 Receptors in Hyporeactive Patients Under Clopidogrel Treatment A Possible Mechanism of HOTPR(High On-Treatment Platelet Reactivity)

Condition:   Stable Angina
Interventions:   Drug: clopidogrel;   Drug: Placebos
Sponsor:   Taipei City Hospital
Recruiting - verified June 2017

The FAVOR II China Study

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Cardiovascular Diseases;   Arteriosclerosis;   Coronary Disease;   Arterial Occlusive Diseases;   Heart Diseases;   Vascular Diseases
Intervention:   Diagnostic Test: Fractional Flow Reserve (FFR)
Sponsors:   China National Center for Cardiovascular Diseases;   Pulse Medical Imaging Technology (Shanghai) Co., Ltd
Recruiting - verified June 2017

Impact of Traditional Chinese Medicine on the Gut Microbiota-dependent Trimethylamine N-oxide

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Compound Panax Notoginseng Granule;   Drug: Placebo Granule
Sponsors:   Guangdong Provincial Hospital of Traditional Chinese Medicine;   Beijing Genomics Institute
Not yet recruiting - verified June 2017

A Study to Compare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are Administered

Condition:   Sickle Cell Disease
Interventions:   Drug: Ticagrelor granule;   Drug: Ticagrelor pediatric tablets;   Drug: Ticagrelor pediatric tablets suspended in water;   Drug: Ticagrelor immediate release (IR) tablets (Commercial tablet)
Sponsors:   AstraZeneca;   Parexel
Active, not recruiting - verified June 2017

Hybrid Coronary Revascularization Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: Left Internal Mammary Artery (LIMA) to LAD;   Procedure: PCI with metallic DES of non-LAD vessel(s);   Procedure: Percutaneous Coronary Intervention
Sponsors:   Icahn School of Medicine at Mount Sinai;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified June 2017

Implication of Cardiac Shock Wave Therapy on Coronary Heart Disease

Condition:   Cardiac Ischemia
Interventions:   Device: Cardiac shock wave therapy;   Other: Sham cardiac shock wave (Control group)
Sponsor:   Beijing Hospital
Recruiting - verified June 2017

Efficacy Study of Oral Nicorandil on Improving Microvascular Function in Female Non-obstructive Coronary Artery Disease (CAD) Subjects

Condition:   Non-obstructive Coronary Artery Disease
Interventions:   Drug: Nicorandil;   Drug: Standard treatment
Sponsor:   Merck KGaA
Recruiting - verified June 2017

Diagnostic Accuracy of On-line Quantitative Flow Ratio (QFR). FAVOR II Europe-Japan

Condition:   Coronary Artery Disease
Intervention:   Other: QFR (observational)
Sponsor:   Aarhus University Hospital Skejby
Recruiting - verified June 2017

Statin Therapy In Patients With Vasospastic Angina

Conditions:   Angina Pectoris, Variant;   Statins, HMG-CoA
Interventions:   Drug: Atorvastatin;   Drug: Placebo
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Withdrawn - verified June 2017

A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: semaglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Recruiting - verified June 2017

A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease

Condition:   Prostate Cancer
Interventions:   Drug: Degarelix;   Drug: Leuprolide
Sponsors:   Ferring Pharmaceuticals;   Memorial Sloan Kettering Cancer Center;   Duke Clinical Research Institute
Recruiting - verified June 2017

WISE CVD - Continuation (WISE HFpEF)

Conditions:   Microvascular Coronary Dysfunction;   Cardiovascular Disease
Interventions:   Procedure: Coronary Angiography;   Procedure: Coronary Reactivity Testing;   Procedure: Cardiac Magnetic Resonance Imaging;   Procedure: Cardiac Magnetic Resonance Angiography;   Procedure: Computed Coronary Tomographic Angiography;   Procedure: Rest-Stress Millar Testing;   Procedure: Aortic vasorelaxation tests
Sponsor:   Cedars-Sinai Medical Center
Recruiting - verified June 2017

XIENCE Xpedition Everolimus-Eluting Coronary Stent Japan Post Marketing Surveillance (XIENCE Xpedition SV Japan PMS)

Conditions:   Ischemic Heart Disease;   Angina Pectoris;   Coronary Artery Disease;   Myocardial Ischemia
Intervention:   Device: XIENCE Xpedition 2.25 mm stent
Sponsor:   Abbott Vascular
Active, not recruiting - verified June 2017

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Active, not recruiting - verified June 2017

Benefits of Exercise Training in Women With Ischemic Syndrome

Condition:   Microvascular Coronary Dysfunction
Intervention:   Behavioral: Exercise training
Sponsor:   Cedars-Sinai Medical Center
Withdrawn - verified June 2017

The Preventive Implantation of Bioresorbable Vascular Scaffold on Functionally Insignificant Stenosis With Vulnerable Plaque Characteristics

Conditions:   Coronary Artery Disease;   Plaque, Atherosclerotic
Interventions:   Device: Bioresorbable Vascular Scaffold;   Drug: Optimal Medical treatment
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified June 2017

Compare the Efficacy of Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft Surgery

Conditions:   Coronary Artery Bypass;   Antiplatelet Agents
Interventions:   Drug: Aspirin;   Drug: Ticagrelor
Sponsor:   Ruijin Hospital
Active, not recruiting - verified June 2017

Improving Echo Measurements in the Diagnosis of Aortic Stenosis

Condition:   Aortic Valve Stenosis
Sponsor:   Baylor Research Institute
Completed - verified June 2017

Safety and Efficacy of Ticagrelor Versus Clopidogrel in Asian/KOREAn Patients With Acute Coronary Syndromes Intended for Invasive Management

Conditions:   Acute Coronary Syndrome;   Myocardial Ischemia;   Heart Diseases;   Cardiovascular Diseases;   Angina Pectoris
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Active, not recruiting - verified June 2017


Condition:   NonST Elevation Myocardial Infarction
Interventions:   Device: Fractional flow reserve;   Other: Magnetic resonance imaging
Sponsors:   NHS National Waiting Times Centre Board;   University of Glasgow;   British Heart Foundation;   NHS Lanarkshire;   NHS Greater Glasgow and Clyde
Completed - verified June 2017

Asan Multivessel Registry

Condition:   Coronary Artery Disease
Intervention:   Other: Treatment
Sponsors:   Seung-Jung Park;   CardioVascular Research Foundation, Korea
Recruiting - verified June 2017

Effects of Ranolazine and Exercise on Daily Physical Activity Trial

Condition:   Chronic Stable Angina
Interventions:   Drug: Ranolazine;   Behavioral: Aerobic Exercise;   Drug: Placebo
Sponsors:   Duke University;   Gilead Sciences
Completed - verified June 2017

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Completed - verified June 2017

Fractional Flow Reserve Versus Angiographically Guided Management to Optimise Outcomes in Unstable Coronary Syndromes

Conditions:   NonST Elevation Myocardial Infarction;   Myocardial Infarction
Intervention:   Device: Fractional flow reserve
Sponsors:   NHS National Waiting Times Centre Board;   British Heart Foundation;   St. Jude Medical;   University of Glasgow
Active, not recruiting - verified June 2017

International Survey of Acute Coronary Syndromes in Transitional Countries

Conditions:   Acute Coronary Syndrome;   Unstable Angina Pectoris;   Myocardial Infarction;   Coronary Disease
Sponsor:   University of Bologna
Recruiting - verified June 2017

An Observational Study of Cholesterol in Coronary Arteries

Conditions:   Myocardial Infarction;   Angina;   Coronary Artery Disease;   Myocardial Ischemia
Intervention:   Device: Intravascular Near Infrared Spectroscopy
Sponsor:   InfraReDx
Completed - verified June 2017