Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Comprehensive Treatment of Angina in Women With Microvascular Dysfunction

Conditions:   Angina Pectoris;   Coronary Microvascular Disease
Interventions:   Dietary Supplement: Diet;   Behavioral: Training;   Drug: Medication (with statin and ACE-inhibition)
Sponsors:   Bispebjerg Hospital;   University Hospital Bispebjerg and Frederiksberg;   Cambridge Weight Plan Limited
Not yet recruiting - verified September 2016

Arteriovenous Fistulae: Drug-eluting Balloon Angioplasty

Condition:   Dysfunction of Native Arteriovenous Fistula of Permanent Haemodialysis Patients
Interventions:   Device: Paclitaxel (Taxol) eluting angioplasty balloon;   Device: high-pressure angioplasty balloon;   Device: low-pressure balloon
Sponsor:   Rennes University Hospital
Not yet recruiting - verified September 2016

Colchicine for Prevention of Vascular Inflammation in Non-cardio Embolic Stroke

Conditions:   Ischemic Attack, Transient;   Stroke
Intervention:   Drug: Colchicine
Sponsors:   University College Dublin;   Health Research Board, Ireland;   Irish Heart Foundation;   University of Limerick;   University of Edinburgh;   National University of Ireland, Galway, Ireland;   Universitat de Lleida;   Universitaire Ziekenhuizen Leuven;   University of Athens
Not yet recruiting - verified September 2016

Acute Coronary Syndrome Sri Lanka Audit Project

Conditions:   Acute Coronary Syndrome;   Unstable Angina;   Non ST Elevation Myocardial Infarction;   ST Elevation Myocardial Infarction
Intervention:   Drug: aspirin, clopidogrel, statin, enoxaparin, streptokinase
Sponsors:   University of Colombo;   Ministry of Health, Sri Lanka
Withdrawn - verified September 2016

The Syndrome X-ercise Study SYNDEX

Condition:   Angina
Intervention:   Other: Exercise training
Sponsors:   Helse Stavanger HF;   University of Bergen;   University of Stavanger
Recruiting - verified September 2016

The Effect of Dan-shen Extract On Lipoprotein Associated PHospholipase A2 Levels IN Patients With Stable Angina Pectoris

Conditions:   Angina, Stable;   Inflammation
Interventions:   Drug: Dan-shen extract;   Drug: Placebo;   Other: Standard medical care
Sponsors:   Taizhou Fourth People's Hospital;   Shanghai 10th People's Hospital
Recruiting - verified September 2016

A Prospective, Single-arm, Multi-centre, Observational, Real World Registry

Condition:   Angina Pectoris
Intervention:   Device: Sirolimus Eluting Coronary Stent System
Sponsor:   Meril Life Sciences Pvt. Ltd.
Not yet recruiting - verified September 2016

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

Conditions:   Cardiomyopathy, Hypertrophic;   Cardiomyopathy, Hypertrophic, Familial
Intervention:   Drug: Perhexiline
Sponsor:   Heart Metabolics Limited
Recruiting - verified September 2016

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment - at the Time of Coronary Angiography - Affect Management Strategy, Hospital Costs and Outcomes?

Conditions:   Chest Pain;   Stable Angina;   Acute Coronary Syndrome;   Non ST Segment Elevation Acute Coronary Syndrome
Intervention:   Device: Routine Measurement of FFR
Sponsors:   University Hospital Southampton NHS Foundation Trust.;   Liverpool Heart and Chest Hospital NHS Foundation Trust
Not yet recruiting - verified September 2016

Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention

Conditions:   Radial Artery Spasm;   Angina;   Coronary Artery Disease
Interventions:   Drug: Topical Nitroglycerine;   Drug: Topical Lidocaine
Sponsor:   Aultman Health Foundation
Not yet recruiting - verified September 2016

The Wire-free Invasive Functional Imaging (WIFI) Study

Condition:   Coronary Artery Disease
Intervention:   Other: QFR (observational)
Sponsor:   Niels Ramsing Holm
Recruiting - verified September 2016

Drug Eluting Balloon for Treatment of Unstable Angina

Condition:   Angina, Unstable
Interventions:   Device: drug eluting balloon; cutting balloon;   Device: drug eluting stent
Sponsor:   Yun Dai Chen
Recruiting - verified September 2016

MYocardial DAmage AND MIcrobiota STUDY

Conditions:   Chronic Stable Angina;   Periprocedural Myocardial Damage
Interventions:   Dietary Supplement: Probiotic;   Other: Placebo
Sponsors:   San Filippo Neri General Hospital;   MENDES S.A., Lugano, Switzerland;   University of Roma La Sapienza
Not yet recruiting - verified September 2016

Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial

Conditions:   Stable Angina;   Unstable Angina;   Non-ST Segment Elevation Myocardial Infarction
Interventions:   Device: CX-ISAR;   Device: Orsiro;   Drug: 3-months DAPT;   Drug: 1-year DAPT
Sponsors:   Seoul National University Hospital;   B. Braun Korea Co., Ltd.
Recruiting - verified September 2016

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Active, not recruiting - verified September 2016

Improvement of Subjective Well-Being by Ranolazine Among Unrevascularized Chronic Stable Coronary Artery Disease Patients

Condition:   Angina
Interventions:   Drug: Ranolazine;   Drug: Sugar pill
Sponsors:   North Florida Foundation for Research and Education;   Gilead Sciences
Completed - verified September 2016


Conditions:   Coronary Artery Disease;   Angina Pectoris;   Myocardial Infarction
Interventions:   Device: Everolimus eluting bioresorbable polymer stent;   Device: Biolimus eluting bioresorbable polymer stent
Sponsors:   Aarhus University Hospital Skejby;   Biosensors International;   Boston Scientific Corporation
Active, not recruiting - verified September 2016

Consistent CTO Trial

Condition:   Chronic Total Occlusion
Intervention:   Device: Percutaneous coronary intervention
Sponsors:   European Cardiovascular Research Center;   Ceric Sàrl
Recruiting - verified September 2016

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified September 2016

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Placebo
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified September 2016

Observational Study of Pediatric Acute Kidney Injury, Risk Factors and Outcomes

Condition:   Acute Kidney Injury
Sponsor:   Children's Hospital Medical Center, Cincinnati
Completed - verified September 2016

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified September 2016

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Active, not recruiting - verified September 2016

Long-Term rIsk, Clinical manaGement and Healthcare Resource Utilization of Stable CAD in Post MI Patients

Condition:   Stable Coronary Artery Disease (CAD), Myocardial Infarction
Sponsor:   AstraZeneca
Active, not recruiting - verified September 2016

Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia

Conditions:   Coronary Artery Disease;   Angina, Stable;   Exercise Test;   Biological Markers;   SPECT
Sponsor:   University Hospital, Basel, Switzerland
Recruiting - verified September 2016

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention &Amp; Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified September 2016

Multicenter Trial to Evaluate the Effect of Dapagliflozin on the Incidence of Cardiovascular Events

Conditions:   Diabetes Mellitus, Non-Insulin-Dependent;   High Risk for Cardiovascular Event
Interventions:   Drug: Dapagliflozin 10 mg;   Drug: Placebo tablet
Sponsors:   AstraZeneca;   Bristol-Myers Squibb;   The TIMI Study Group;   Hadassah Medical Organization
Active, not recruiting - verified September 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: Placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified September 2016

The Nordic-Baltic Bifurcation Study IV

Condition:   Coronary Artery Disease
Interventions:   Procedure: Implantation of coronary stent in bifurcation lesion;   Procedure: Implantation of coronary stent in bifurcation lesion
Sponsors:   Niels Ramsing Holm;   Johnson & Johnson
Active, not recruiting - verified September 2016

Post-authorization Safety Study of Etoricoxib and Other Anti-inflammatory Therapies in European Patients With Ankylosing Spondylitis (MK-0663-163)

Condition:   Ankylosing Spondylitis
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified September 2016

The Nordic Bifurcation Study III

Condition:   Coronary Artery Disease
Intervention:   Procedure: Percutaneous coronary intervention (PCI)
Sponsors:   Niels Ramsing Holm;   Johnson & Johnson
Active, not recruiting - verified September 2016

Study of Women With Acute Coronary Syndromes and Nonobstructive Coronary Artery Disease

Condition:   Acute Coronary Syndromes
Interventions:   Procedure: Intravascular ultrasound;   Procedure: MRI
Sponsors:   New York University School of Medicine;   Doris Duke Charitable Foundation
Active, not recruiting - verified September 2016

Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study

Conditions:   Myocardial Infarction;   Angina, Unstable
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation
Recruiting - verified September 2016

Michelangelo - Oasis 5

Condition:   Thromboembolism
Interventions:   Drug: Fondaparinux;   Drug: enoxaparin
Sponsors:   GlaxoSmithKline;   University of Chicago;   Organon;   Sanofi;   Duke University
Completed - verified September 2016