Angina

Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Morbidity and Mortality in Patients With Hypertrophic Cardiomyopathy: a CALIBER Study

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Other: No intervention
Sponsors:   University College, London;   Inherited Cardiac Diseases Unit, The Heart Hospital, London
Active, not recruiting - verified April 2015

Efficacy of Ranolazine in Patients With Chronic Total Occlusions of Coronary Arteries

Conditions:   Myocardial Ischemia;   Coronary Artery Disease;   Arteriosclerosis;   Chronic Stable Angina
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsors:   East Carolina University;   Gilead Sciences
Not yet recruiting - verified April 2015

An Epidemiological Cohort Study of Acute Coronary Syndromes in The Greek Population. The PHAETHON Study

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Hellenic Cardiovascular Research Society
Completed - verified April 2015

A Trial in Stable Intermediate Coronary Lesions and Grey-zone FFR Values

Conditions:   Grey-zone Fractional Flow Reserve;   Intermediate Coronary Lesions;   Stable Angina;   Coronary Physiology
Interventions:   Procedure: PCI;   Drug: Optimal Medical Therapy
Sponsors:   Golden Jubilee National Hospital;   British Heart Foundation;   University of Glasgow
Not yet recruiting - verified March 2015

Different Doses of Rosuvastatin Therapy on Regression of Critical Coronary Atherosclerosis in ACS Patients

Condition:   Acute Coronary Syndrome
Intervention:   Drug: rosuvastatin
Sponsor:   Beijing Friendship Hospital
Not yet recruiting - verified April 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Not yet recruiting - verified April 2015

Researches of Retinal Artery Lesions and Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Capital Medical University
Active, not recruiting - verified April 2015

An Observational Prospective Study to Understand the Usage Pattern of Ticagrelor With ACS (Acute Coronary Syndrome)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Not yet recruiting - verified April 2015

Dose-escalation, Repeated and Single Oral Dosing Study

Condition:   Acute Coronary Syndrome
Interventions:   Drug: APD791;   Drug: Clopidogrel;   Drug: Aspirin;   Drug: Placebo for APD791
Sponsors:   IlDong Pharmaceutical Co Ltd;   Asan Medical Center
Enrolling by invitation - verified April 2015

Jakarta Acute Coronary Syndrome Registry

Condition:   Acute Coronary Syndrome
Intervention:   Other: JAC Registry
Sponsor:   National Cardiovascular Center Harapan Kita Hospital Indonesia
Recruiting - verified April 2015

Outcome After Coronary Artery Bypass Grafting

Conditions:   Coronary Artery Disease;   Myocardial Infarction;   Angina Pectoris
Intervention:   Procedure: Coronary artery bypass surgery
Sponsors:   University of Oulu;   Universita di Verona;   Ospedali Riuniti Trieste;   University of Catania;   University of Leicester;   Centre Hospitalier Universitaire de Besancon;   Karolinska Institutet;   San Camillo Hospital, Rome;   Rennes University Hospital;   S. Anna Hospital;   Paracelsus Medical University;   Second University of Naples;   University of Parma
Recruiting - verified April 2015

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Not yet recruiting - verified April 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified April 2015

Ascertainment of EMR-based Clinical Covariates Among Patients Receiving Oral and Non-insulin Injected Hypoglycemic Therapy

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsor:   Boehringer Ingelheim
Completed - verified April 2015

Ranolazine and Microvascular Angina by PET in the Emergency Department

Condition:   Microvascular Angina
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsors:   Yale University;   Gilead Sciences
Recruiting - verified April 2015

Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease

Conditions:   Myocardial Infarction;   Ischemic Stroke;   Stroke;   Subarachnoid Haemorrhage;   Venous Thrombosis;   Transient Ischemic Attack;   Stable Angina Pectoris;   Unstable Angina;   Heart Failure;   Peripheral Arterial Disease;   Abdominal Aortic Aneurysm
Intervention:   Other: No intervention
Sponsors:   University College, London;   Wellcome Trust;   National Institute for Health Research, United Kingdom
Active, not recruiting - verified April 2015

Danhong Injection in the Treatment of Unstable Angina Pectoris

Condition:   Unstable Angina Pectoris
Interventions:   Drug: Danhong injection;   Other: Standard medical care;   Drug: Placebo
Sponsors:   China  Academy of Chinese Medical Sciences;   China Food and Drug Administration  
Recruiting - verified April 2015

Cardiovascular Outcomes Following Treatment With Ertugliflozin in Participants With Type 2 Diabetes Mellitus and Established Vascular Disease (MK-8835-004)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Recruiting - verified April 2015

ISCHEMIA-Chronic Kidney Disease Trial

Conditions:   Cardiovascular Diseases;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia;   Kidney Disease;   End Stage Renal Failure on Dialysis
Interventions:   Procedure: Cardiac Catheterization;   Procedure: Coronary Artery Bypass Graft Surgery;   Procedure: Percutaneous Coronary Intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   New York University School of Medicine;   New York University;   National Heart, Lung, and Blood Institute (NHLBI);   Vanderbilt University;   Albany Stratton VA Medical Center;   East Carolina University;   Duke University;   Stanford University;   Harvard University;   Columbia University
Recruiting - verified April 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified April 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified April 2015

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Recruiting - verified April 2015

Intracoronary Autologous Mesenchymal Stem Cells Implantation in Patients With Ischemic Dilated Cardiomyopathy

Condition:   Ischemic Dilated Cardiomyopathy
Intervention:   Other: BM-MSCs
Sponsors:   National University of Malaysia;   Cytopeutics Sdn Bhd
Active, not recruiting - verified April 2015

Danhong Injection in the Treatment of Chronic Stable Angina

Condition:   Chronic Stable Angina
Interventions:   Drug: Danhong injection;   Other: Standard medical care;   Drug: Placebo
Sponsors:   China  Academy of Chinese Medical Sciences;   China: State Food and Drug Administration
Recruiting - verified April 2015

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab SAR236553 (REGN727)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Other: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified April 2015

The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes

Conditions:   Coronary Artery Disease;   Diabetes Mellitus, Type 2
Interventions:   Drug: Liraglutide;   Drug: Placebo
Sponsor:   Haugaard, Steen Bendix, M.D., DMSc
Active, not recruiting - verified April 2015

Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders.

Condition:   Smoking Cessation
Interventions:   Drug: placebo;   Drug: varenicline tartrate;   Drug: bupropion hydrochloride;   Drug: Nicotine Replacement Therapy Patch
Sponsor:   Pfizer
Recruiting - verified April 2015

Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Injection of Cyclosporin;   Drug: Placebo;   Procedure: Echocardiography
Sponsor:   Hospices Civils de Lyon
Active, not recruiting - verified April 2015

Long-term Results Following Endoscopic Vein Harvesting in Coronary Artery Bypass Surgery

Condition:   Angina Pectoris
Intervention:   Procedure: Surgery
Sponsors:   Aalborg Universitetshospital  ;   Aalborg University
Completed - verified November 2011

Fondaparinux EU-RMP (Adherence)

Conditions:   ST-elevation Myocardial Infarction;   Unstable Angina;   Non ST Segment Elevation Myocardial Infarction;   Acute Coronary Syndrome
Intervention:   Drug: fondaparinux
Sponsor:   GlaxoSmithKline
Completed - verified April 2015

Comparison Between FFR Guided Revascularization Versus Conventional Strategy in Acute STEMI Patients With MVD.

Conditions:   Myocardial Infarction;   Multivessel Coronary Artery Disease
Interventions:   Procedure: FFR-guided revascularisation strategy;   Procedure: randomised to guidelines group
Sponsors:   Maasstad Hospital;   Abbott Vascular;   St. Jude Medical
Recruiting - verified April 2015

Tight Hemodynamic Control in Patients Who Are Chronically on Metoprolol

Conditions:   Vascular Disease;   Hypertension;   Angina;   Cardiac Disease
Interventions:   Drug: Esmolol;   Drug: Metoprolol
Sponsors:   University Health Network, Toronto;   Baxter Healthcare Corporation
Terminated - verified April 2015

Ranolazine and Pulmonary Hypertension

Conditions:   Angina;   Pulmonary Arterial Hypertension
Intervention:   Drug: Ranolazine
Sponsors:   Northwestern University;   Gilead Sciences
Completed - verified April 2015

XIENCE V/PROMUS Everolimus-Eluting Stent System Post-marketing Surveillance Protocol for Japan

Conditions:   Angina;   Chronic Coronary Occlusion;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Intervention:   Device: XIENCE V / PROMUS stent
Sponsor:   Abbott Vascular
Active, not recruiting - verified April 2015

The Effect of Training on Endothelial Function, Progression of Disease,Inflammation, Heart Rate Variability and Mental Health After Percutaneous Coronary Intervention

Condition:   Coronary Artery Disease
Intervention:   Behavioral: exercise training
Sponsor:   Helse Stavanger HF
Completed - verified February 2009

Cardiac Rehabilitation for the Treatment of Refractory Angina

Conditions:   Angina Pectoris;   Coronary Disease
Intervention:   Behavioral: Cardiac rehabilitation
Sponsors:   National Heart and Lung Institute;   British Heart Foundation;   Royal Brompton & Harefield NHS Foundation Trust
Completed - verified April 2015

PET and Recovery Following Revascularization (PARR 2)

Conditions:   Coronary Artery Disease;   Ventricular Dysfunction, Left
Interventions:   Procedure: Positron emission tomography: FDG viability imaging;   Other: PET imaging
Sponsors:   Ottawa Heart Institute Research Corporation;   Canadian Institutes of Health Research  (CIHR);   Heart and Stroke Foundation of Ontario
Completed - verified April 2015

Exercise-training Before Coronary Artery Bypass Graft (CABG)

Conditions:   Angina;   Coronary Artery Disease
Intervention:   Behavioral: Exercise training
Sponsor:   Norwegian University of Science and Technology
Recruiting - verified April 2015

Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke

Condition:   Cardiovascular Disease
Intervention:   Drug: atorvastatin
Sponsor:   Pfizer
Completed - verified April 2015

The Impact of Cardiac Rehabilitation Participation on Cardiac Syndrome X

Condition:   Microvascular Angina
Intervention:   Procedure: Phase III group-based cardiac rehabilitation
Sponsors:   National Heart and Lung Institute;   Royal Brompton & Harefield NHS Foundation Trust
Completed - verified April 2015

Get CardioSmart

You're Invited