Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability

Conditions:   Myocardial Infarction;   Myocardial Ischemia;   Atherosclerosis;   Coronary Artery Disease;   Coronary Stenosis;   Heart Attack;   Multi Vessel Coronary Artery Disease
Interventions:   Diagnostic Test: PET-MRI;   Procedure: Optical Coherence Tomography
Sponsors:   Maastricht University Medical Center;   VieCuri Medical Centre;   Stichting de Weijerhorst
Not yet recruiting - verified August 2017

GLOBAL LEADERS Adjudication Sub-Study

Conditions:   Coronary Artery Disease;   Platelet-aggregation Inhibitors
Sponsors:   University Hospital Inselspital, Berne;   European Cardiovascular Research Center
Active, not recruiting - verified August 2017

Hybrid Coronary Revascularization Trial

Condition:   Coronary Artery Disease
Interventions:   Procedure: Hybrid Coronary Revascularization;   Device: Hybrid Coronary Revascularization;   Device: Percutaneous Coronary Intervention
Sponsors:   Emilia Bagiella;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified August 2017

Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury

Condition:   TBI
Interventions:   Drug: Sildenafil citrate;   Device: Functional Near Infared Spectroscopy;   Other: Hypercapnia Challenge
Sponsor:   University of Pennsylvania
Recruiting - verified August 2017

Influence of Naloxone on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine

Condition:   Unstable Angina Pectoris
Interventions:   Drug: Crushed ticagrelor followed by morphine;   Drug: Crushed ticagrelor, morphine,naloxone
Sponsor:   Collegium Medicum w Bydgoszczy
Recruiting - verified August 2017

Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine

Condition:   Unstable Angina Pectoris
Interventions:   Drug: Crushed ticagrelor followed by morphine;   Drug: Crushed ticagrelor, morphine,metoclopramide
Sponsor:   Collegium Medicum w Bydgoszczy
Recruiting - verified August 2017

Reducing Acute Coronary Syndrome Patient Delay

Condition:   Acute Coronary Syndrome
Interventions:   Behavioral: Text+Visual BCT-based intervention;   Behavioral: Text-only BCT intervention;   Behavioral: Leaflet information (control)
Sponsors:   Edinburgh Napier University;   University of Stirling;   University of Aberdeen;   University of Dundee;   The University of New South Wales
Recruiting - verified August 2017

Comparison of the Vasomotor Function and Myocardial Flow in Patients Treated With Bioresorbable and Metallic Stents at 1 Year

Condition:   Stable Angina
Interventions:   Device: Bioresorbable vascular scaffold;   Device: Everolimus-eluting stent
Sponsors:   Institut d'Investigació Biomèdica de Bellvitge;   Fundació La Marató de TV3
Active, not recruiting - verified August 2017

Cardiac Rehabilitation Program in Improving Cardiorespiratory Fitness in Stage 0-III Breast Cancer Survivors

Conditions:   Cancer Survivor;   Stage 0 Breast Cancer;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage IIA Breast Cancer;   Stage IIB Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions:   Other: Educational Intervention;   Behavioral: Exercise Intervention;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
Sponsor:   Ohio State University Comprehensive Cancer Center
Recruiting - verified August 2017

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Active, not recruiting - verified August 2017

Development of a Novel Stress Testing Protocol to Define the Relationship Between Coronary Microvascular Dysfunction and Diastology in Women With Angina But No Evidence of Obstructive Coronary Artery Disease

Condition:   Microvascular Coronary Dysfunction
Interventions:   Other: Handgrip;   Other: Altitude simulation;   Other: Leg exercise
Sponsor:   Cedars-Sinai Medical Center
Recruiting - verified August 2017

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Sponsor:   AstraZeneca
Active, not recruiting - verified August 2017

Exercise as a Life-long Medicine in Patients With Coronary Artery Disease

Conditions:   Cardiovascular Diseases;   Myocardial Infarction;   Angina (Stable)
Interventions:   Behavioral: high-intensity exercise training;   Behavioral: web-based follow-up program;   Behavioral: usual care
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital;   Levanger Hospital
Recruiting - verified August 2017

Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis

Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting - verified August 2017

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   Cleveland Clinic Coordinating Center for Clinical Research (C5R);   Quintiles, Inc.
Active, not recruiting - verified August 2017

Randomized Trial Comparing Diltiazem and Metoprolol For Atrial Fibrillation Rate Control

Conditions:   Atrial Fibrillation;   Atrial Flutter
Interventions:   Drug: Metoprolol;   Drug: Diltiazem
Sponsor:   CAMC Health System
Recruiting - verified August 2017


Condition:   Acute ST Segment Elevation Myocardial Infarction
Intervention:   Device: Percutaneous Coronary Intervention
Sponsors:   ECRI bv;   Abbott Vascular;   Terumo Europe N.V.
Active, not recruiting - verified August 2017

Kansai Plus Atrial Fibrillation Trial

Condition:   Atrial Fibrillation
Interventions:   Procedure: ATP guide additional ablation.;   Drug: Antiarrhythmic drug (AAD);   Procedure: ATP guide additional ablation.;   Drug: Control;   Procedure: Control;   Drug: Antiarrhythmic drug (AAD);   Procedure: Control;   Drug: Control
Sponsor:   Kyoto University, Graduate School of Medicine
Completed - verified August 2017

Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Comorbidities

Condition:   Cardiovascular Disease
Interventions:   Drug: Febuxostat;   Drug: Allopurinol
Sponsors:   Takeda;   Teijin America, Inc.
Completed - verified August 2017

Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study

Conditions:   Myocardial Infarction;   Angina, Unstable
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation
Recruiting - verified August 2017