Angina

Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

OCT-Features in Culprit and Not Culprit Coronary Plaque in ACS Patients

Conditions:   Acute Coronary Syndrome;   Culprit Plaque;   Non Culprit Plaque
Intervention:   Other: optical coherence tomography
Sponsor:   Azienda Ospedaliera Città della Salute e della Scienza di Torino
Recruiting - verified June 2015

Optimal Dose of Acetylsalicylic Acid After Coronary Artery Bypass Grafting

Condition:   Stable Coronary Artery Disease With Coronary Artery Bypass Grafting
Intervention:   Drug: Acetylsalicylic acid
Sponsors:   Karolinska University Hospital;   Karolinska Institutet
Active, not recruiting - verified June 2015

Comparison of Ticagrelor vs. Prasugrel on Inflammation, Arterial Stiffness, Endothelial Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Coronary Stenting

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Ticagrelor;   Drug: Prasugrel
Sponsors:   Korea University Anam Hospital;   AstraZeneca
Not yet recruiting - verified June 2015

The Risk of Major Bleeding With Novel Anti-platelets: A Comparison of Ticagrelor With Clopidogrel in a Real World Population of 5000 Patients Treated for Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Bleeding;   Novel Anti-platelets;   Ticagrelor;   Clopidogrel
Intervention:   Drug: Ticagrelor
Sponsors:   Aintree University Hospitals NHS Foundation Trust;   Liverpool Heart and Chest Hospital NHS Foundation Trust;   Royal Liverpool and Broadgreen University Hospitals NHS Trust;   Countess of Chester NHS Foundation Trust;   St Helens & Knowsley Teaching Hospitals NHS Trust
Recruiting - verified June 2015

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Intervention:   Drug: CER-001
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Not yet recruiting - verified June 2015

Lacunar Intervention Trial 1 (LACI-1)

Conditions:   Cerebral Small Vessel Diseases;   Cognitive Impairment;   Stroke
Interventions:   Drug: isosorbide mononitrate;   Drug: cilostazol
Sponsors:   University of Edinburgh;   University of Nottingham
Not yet recruiting - verified June 2015

Effectiveness of Advanced Practice Nurse-Led Telehealth on Readmissions

Conditions:   Acute Myocardial Infarction;   Acute Coronary Syndrome
Intervention:   Other: APN-led Telemedicine
Sponsors:   National University Heart Centre, Singapore;   National University Hospital, Singapore
Not yet recruiting - verified June 2015

Impact of Care Transition on Medication Adherence in Cardiac Patients

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   King's College London
Not yet recruiting - verified June 2015

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus
Interventions:   Biological: Albiglutide 30 mg;   Biological: Albiglutide 50 mg;   Biological: Albiglutide matching placebo
Sponsors:   GlaxoSmithKline;   Duke Clinical Research Institute
Not yet recruiting - verified June 2015

An Observational Prospective Study to Understand the Usage Pattern of Ticagrelor With ACS (Acute Coronary Syndrome)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified June 2015

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study

Condition:   Cost Sharing, Acute Coronary Syndrome,
Intervention:   Other: Study voucher card
Sponsors:   AstraZeneca;   Duke Clinical Research Institute
Recruiting - verified June 2015

Patient and Provider Assessment of Lipid Management Registry

Conditions:   Hyperlipidemia;   Hypercholesterolemia;   Cardiovascular Disease;   Diabetes;   Chronic Kidney Disease (CKD);   Hypertension;   Smoking;   Myocardial Infarction (MI);   Unstable Angina;   Angina;   Coronary Artery Disease (CAD);   Stroke;   Transient Ischemic Attack (TIA);   Carotid Stenosis;   Peripheral Arterial Disease;   Atherosclerosis;   Claudication
Intervention:  
Sponsors:   Duke University;   Regeneron Pharmaceuticals;   Sanofi
Recruiting - verified June 2015

Screening for Chronic Obstructive Pulmonary Disease in Patients With Acute Coronary Syndromes

Conditions:   Chronic Obstructive Pulmonary Disease;   Acute Coronary Syndromes
Intervention:   Other: screening test
Sponsor:   University Hospital of Ferrara
Active, not recruiting - verified July 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified June 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified June 2015

Study of a Quality Improvement Toolkit in Kerala, India, Among Hospitals Treating Acute Coronary Syndrome Patients

Condition:   Acute Coronary Syndrome
Intervention:   Behavioral: Quality Improvement Toolkit
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 2015

Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study

Conditions:   Abdominal Aortic Aneurysm;   Coronary Heart Disease;   Sudden Cardiac Death;   Intracerebral Haemorrhage;   Heart Failure;   Ischemic Stroke;   Myocardial Infarction;   Stroke;   Peripheral Arterial Disease;   Stable Angina Pectoris;   Subarachnoid Haemorrhage;   Transient Ischemic Attack;   Unstable Angina;   Cardiac Arrest
Intervention:  
Sponsors:   University College, London;   Wellcome Trust;   National Institute for Health Research, United Kingdom;   London School of Hygiene and Tropical Medicine
Active, not recruiting - verified July 2015

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Condition:   Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions:   Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
Sponsors:   AstraZeneca;   The Cleveland Clinic
Recruiting - verified June 2015

Ticagrelor vs Clopidogrel in Non-ST Elevation Acute Coronary Syndrome Patients Undergoing PCI With Bivalirudin.

Condition:   Non-ST Elevation Acute Coronary Syndrome
Interventions:   Drug: ticagrelor;   Drug: clopidogrel
Sponsor:   AstraZeneca
Terminated - verified June 2015

Cardiovascular Outcomes Following Treatment With Ertugliflozin in Participants With Type 2 Diabetes Mellitus and Established Vascular Disease (MK-8835-004)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Recruiting - verified June 2015

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Condition:   Cardiovascular Disease
Interventions:   Drug: bococizumab (PF-04950615);   Drug: Placebo
Sponsor:   Pfizer
Recruiting - verified July 2015

Different LD of Ticagrelor for Antiplatelet Effect in Patients With Non-ST-segment Elevation ACS Undergoing PCI

Condition:   Non ST Segment Elevation Acute Coronary Syndrome
Intervention:   Drug: ticagrelor
Sponsor:   General Hospital of Chinese Armed Police Forces
Recruiting - verified January 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified June 2015

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

Condition:   Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Withdrawn - verified July 2015

Ticagrelor and Eptifibatide Bolus-Only Versus Ticagrelor and Eptifibatide Bolus Plus Abbreviated Infusion

Condition:   Acute Coronary Syndrome
Interventions:   Drug: ticagrelor;   Drug: Eptifibatide
Sponsors:   University of Alabama at Birmingham;   AstraZeneca
Active, not recruiting - verified June 2015

Efficacy and Safety Study of Ticagrelor

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsor:   General Hospital of Chinese Armed Police Forces
Recruiting - verified March 2015

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Condition:   Dyslipidemia
Interventions:   Biological: Evolocumab (AMG 145);   Other: Placebo;   Drug: Effective statin therapy
Sponsor:   Amgen
Active, not recruiting - verified June 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified June 2015

Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders.

Condition:   Smoking Cessation
Interventions:   Drug: placebo;   Drug: varenicline tartrate;   Drug: bupropion hydrochloride;   Drug: Nicotine Replacement Therapy Patch
Sponsor:   Pfizer
Active, not recruiting - verified June 2015

Treatment With Ranolazine in Microvascular Coronary Dysfunction (MCD): Impact on Angina Myocardial Ischemia

Condition:   Microvascular Coronary Dysfunction (MCD)
Interventions:   Drug: Ranolazine;   Drug: Placebo
Sponsors:   Cedars-Sinai Medical Center;   University of Florida
Recruiting - verified June 2015

A Study of RoActemra/Actemra (Tocilizumab) in Comparison to Etanercept in Patients With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Condition:   Cardiovascular Disease, Rheumatoid Arthritis
Interventions:   Drug: etanercept;   Drug: tocilizumab [RoActemra/Actemra]
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified July 2015

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified July 2015

Efficacy of Topical Capsaicin Cream for Stable Angina

Condition:   Stable Angina
Interventions:   Drug: Capsaicin;   Other: Placebo cream
Sponsors:   Neal Weintraub;   University of Cincinnati
Terminated - verified June 2015

Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression

Conditions:   Atherosclerosis;   Hypercholesterolemia
Interventions:   Drug: Statin Drugs;   Other: HMG-CoA Reductase Inhibitors
Sponsor:   National Institutes of Health Clinical Center (CC)
Active, not recruiting - verified April 2015

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified July 2015

BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: D,L-lysine acetylsalicylate (Aspirin, BAY81-8781) 500 mg IV;   Drug: D,L-lysine acetylsalicylate (Aspirin, BAY81-8781) 250 mg IV;   Drug: Acetylsalicylic acid (Aspirin, BAYe4465) 300 mg Tablet
Sponsor:   Bayer
Completed - verified June 2015

Sitagliptin Cardiovascular Outcome Study (MK-0431-082)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Sitagliptin phosphate;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Duke Clinical Research Institute, Oxford Diabetes Trials Unit
Completed - verified June 2015

ACT34-CMI -- Adult Autologous CD34+ Stem Cells (Follow-Up Study)

Condition:   Myocardial Ischemia
Intervention:  
Sponsor:   Baxalta US Inc.
Completed - verified July 2010

Cardiology Biobank Registry

Condition:   Cardiovascular Disease
Intervention:  
Sponsor:   Emory University
Recruiting - verified June 2015

The BEAUTIFUL Study: Effects of Ivabradine in Patients With Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction

Conditions:   Coronary Disease;   Ventricular Dysfunction, Left
Interventions:   Drug: Ivabradine;   Drug: Placebo
Sponsor:   Institut de Recherches Internationales Servier
Completed - verified June 2015

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