Acute Coronary Syndrome

Clinical Trial Finder

Many patients with acute coronary syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Sequential Coronary CT-angiography and Biomarkers

Conditions:   Coronary Artery Disease;   Atherosclerosis
Interventions:   Radiation: Coronary CT-angiography;   Other: Assesment of biomarkers involved in atherothrombosis
Sponsor:   Maastricht University Medical Center
Recruiting - verified March 2015

Acute Kidney Outreach to Reduce Deterioration and Death (AKORDD)

Condition:   Acute Kidney Injury
Interventions:   Other: Rapid diagnosis of AKI cause;   Other: Rapid treatment of AKI cause;   Other: Stopping 'nephrotoxic' drugs;   Other: Early nephrology followup for stage 3 AKI;   Other: Preventing recurrent AKI;   Other: Good standard care
Sponsors:   Heart of England NHS Trust;   University of Birmingham;   University of Warwick
Active, not recruiting - verified March 2015

Clinical Trial to Evaluate the Use of an Adsorption Membrane (OXIRIS®) During Cardiopulmonary Bypass Surgery

Conditions:   Cardiac Surgical Procedures;   Cardiopulmonary Bypass
Intervention:   Device: OXIRIS®
Sponsors:   Hospital Universitari de Bellvitge;   Gambro Renal Products, Inc.
Active, not recruiting - verified March 2015

PLX3397 in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)

Conditions:   Neurofibroma, Plexiform;   Precursor Cell Lymphoblastic Leukemia-Lymphoma;   Leukemia, Prolymphocytic, Acute;   Sarcoma
Intervention:   Drug: PLX3397
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified March 2014

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Not yet recruiting - verified March 2015

Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers

Conditions:   Myocardial Infarction;   Inflammation;   Acute Coronary Syndrome (ACS);   Reperfusion Injury
Interventions:   Biological: Salmonella typhi vaccine (Typhim Vi®);   Drug: Oxygen (Oxymask®);   Drug: Atorvastatin
Sponsors:   Karolinska Institutet;   University Hospital, Linkoeping
Recruiting - verified March 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified March 2015

Time-motion-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in Emergency Department

Condition:   Respiratory Distress Syndrome, Adult
Intervention:   Device: Vivid S6 GE Ultrasound
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Recruiting - verified March 2015

Is Efficacy of PLAtelet Aggregation Inhibition by Ticagrelor Mediated P2Y12 Blockade Dependent Upon Endogenous Endothelial Nitric OXide?

Condition:   Acute Coronary Syndome
Interventions:   Other: Blood Test;   Other: EndoPAT - endothelial assessment
Sponsor:   Jennifer Rossington
Not yet recruiting - verified March 2015

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified March 2015

Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome

Condition:   Chest Pain
Interventions:   Biological: Blood work in the ambulance;   Biological: Blood work upon arrival in the emergency room;   Biological: Blood work at 3 hours post-arrival in the emergency room
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified March 2015

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Treatment 3 months DAPT;   Drug: Treatment 12 months DAPT
Sponsor:   Diagram B.V.
Recruiting - verified March 2015

Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock

Conditions:   Acute Heart Failure;   Shock
Intervention:  
Sponsor:   Shockomics Consortium
Recruiting - verified September 2014

Efficacy and Safety of New Generation Drug Eluting Stents Associated With an Ultra Short Duration of Dual Antiplatelet Therapy. Design of the Short Duration of Dual antiplatElet Therapy With SyNergy II Stent in Patients Older Than 75 Years Undergoing Percutaneous Coronary Revascularization.

Conditions:   Stable Angina;   Silent Myocardial Ischemia;   Acute Coronary Syndrome
Interventions:   Procedure: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Synergy II stent;   Procedure: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Omega stent;   Procedure: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Rebel stent
Sponsor:   Ceric Sàrl
Recruiting - verified December 2014

Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD

Condition:   Coronary Artery Dissection, Spontaneous
Interventions:   Drug: ramipril;   Drug: rosuvastatin;   Drug: placebo
Sponsor:   Cardiology Research UBC
Recruiting - verified July 2014

Routine Versus Selective Use of FFR to Guide PCI

Conditions:   Acute Coronary Syndrome;   Coronary Atherosclerosis;   Angina, Unstable
Intervention:   Device: Fractional Flow Reserve (FFR)
Sponsors:   Cardiology Research UBC;   Provincial Health Services Authority
Terminated - verified March 2015

Specimen Procurement& Data Collection Protocol for The Rapid Evaluation of Possible Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:   Other: OBSERVATIONAL REGISTRY
Sponsor:   Henry Ford Health System
Recruiting - verified March 2015

Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment For Acute Coronary Syndromes Trial

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel
Sponsor:   Klinikum der Universitaet Muenchen
Recruiting - verified March 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified March 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Phenprocoumon
Sponsor:   Bayer
Recruiting - verified March 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Acenocoumarol
Sponsor:   Bayer
Recruiting - verified March 2015

Modafinil and Cognitive Function in POTS

Condition:   Postural Tachycardia Syndrome
Interventions:   Drug: Placebo;   Drug: Modafinil;   Drug: Propranolol
Sponsor:   Vanderbilt University
Recruiting - verified March 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified March 2015

Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rosuvastatin;   Drug: Atorvastatin
Sponsor:   Centro Cardiopatici Toscani
Recruiting - verified March 2015

High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction
Intervention:   Device: High-sensitivity troponin I assay
Sponsors:   University of Edinburgh;   NHS Lothian;   NHS Greater Glasgow and Clyde;   Abbott Diagnostics Division
Recruiting - verified March 2015

Automated Hovering to Improve Medication Adherence Among Myocardial Infarction Patients (Heartstrong)

Condition:   Patients With Principal or Secondary Diagnosis Code of Intrntl Classification of Diseases, 9th Revision, (ICD-9-CM) 410 (Except When 5th Digit Was 2)
Intervention:   Behavioral: Electronic Pill Bottle, Incentives, Social Influence
Sponsor:   University of Pennsylvania
Active, not recruiting - verified April 2013

An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction

Conditions:   Acute Coronary Syndrome;   Non-ST Elevation (NSTEMI) Myocardial Infarction;   Acute ST Segment Elevation Myocardial Infarction;   Angina, Unstable
Intervention:   Drug: Oxygen
Sponsors:   Karolinska Institutet;   Swedish Heart Lung Foundation;   Swedish Foundation for Strategic Research;   The Swedish Research Council
Recruiting - verified March 2015

Does Optical Coherence Tomography Optimise Results of Stenting

Condition:   Acute Coronary Syndromes
Intervention:   Procedure: OCT
Sponsor:   Centre Hospitalier Universitaire de Besancon
Recruiting - verified March 2015

Reproductibility of TM-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in the ER

Condition:   Respiratory Distress Syndrome, Adult
Interventions:   Procedure: Diaphragm excursion measures 1;   Procedure: Diaphragm excursion measures 2
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Completed - verified March 2015

The Impact of Gratitude on Biology and Behavior in Persons With Heart Disease

Conditions:   Myocardial Infarction;   Unstable Angina
Intervention:  
Sponsors:   Massachusetts General Hospital;   University of California, Berkeley
Completed - verified March 2015

Citalopram for Sx/Util in Acute Coronary Syndrome Patients

Condition:   Acute Coronary Syndrome
Intervention:   Drug: Citalopram
Sponsor:   Henry Ford Health System
Not yet recruiting - verified August 2012

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab SAR236553 (REGN727)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Other: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified March 2015

Acute Versus Subacute Angioplasty in Patients With NON-ST-Elevation Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Procedure: Group I: Primary PCI
Sponsor:   Aarhus University Hospital Skejby
Recruiting - verified March 2015

Antiplatelet Therapy Guided by Thrombelastography in Patients With Acute Coronary Syndromes (TEGCOR Study)

Conditions:   Thrombosis;   Coronary Artery Disease
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel
Sponsor:   Indiana University
Recruiting - verified March 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified March 2015

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Conditions:   Adult Myelodysplastic Syndrome;   Chronic Myelomonocytic Leukemia;   Chronic Myelomonocytic Leukemia-1;   Chronic Myelomonocytic Leukemia-2;   Previously Treated Myelodysplastic Syndrome;   Refractory Anemia With Excess Blasts
Interventions:   Drug: Azacitidine;   Drug: Lenalidomide;   Drug: Vorinostat
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified March 2015

Rubidium-82 Position Emission Computed Tomography (PET) Versus Gated, Rest / Stress Technetium 99-m SPECT

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Heart Disease
Interventions:   Other: SPECT imaging;   Other: PET imaging
Sponsors:   Hartford Hospital;   Bracco Diagnostics, Inc
Completed - verified July 2012

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified March 2015

A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)

Conditions:   Myelodysplastic Syndromes;   Thrombocytopenia
Intervention:   Drug: Eltrombopag
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2014

AngelMed for Early Recognition and Treatment of STEMI

Conditions:   Acute Myocardial Infarction (AMI);   Coronary Occlusion;   Acute Coronary Syndrome
Intervention:   Device: AngelMed Guardian System
Sponsors:   Angel Medical Systems;   Symbios Clinical
Active, not recruiting - verified July 2013

French Registry of Acute Coronary Syndrome

Condition:   Acute Myocardial Infarction
Intervention:   Other: Blood sample
Sponsors:   Assistance Publique - Hôpitaux de Paris;   French Cardiology Society
Active, not recruiting - verified March 2015

A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease

Condition:   Moderate Risk of CVD
Interventions:   Drug: Aspirin (Acetylsalicylic acid, BAYE4465);   Drug: Placebo
Sponsor:   Bayer
Active, not recruiting - verified March 2015

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