Acute Coronary Syndrome

Clinical Trial Finder

Many patients with acute coronary syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Acute Coronary Syndrome Sri Lanka Audit Project

Conditions:   Acute Coronary Syndrome;   Unstable Angina;   Non ST Elevation Myocardial Infarction;   ST Elevation Myocardial Infarction
Intervention:   Drug: aspirin, clopidogrel, statin, enoxaparin, streptokinase
Sponsors:   University of Colombo;   Ministry of Health, Sri Lanka
Withdrawn - verified September 2016

Myeloid-Derived Cells in Cardiac Surgery Patients

Conditions:   Insufficiency; Cardiac, Complicating Surgery;   Systemic Inflammatory Response Syndrome
Interventions:   Device: minimal extracorporeal circulation (MEC);   Procedure: The cytokines modulations
Sponsor:   Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Recruiting - verified September 2016

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment - at the Time of Coronary Angiography - Affect Management Strategy, Hospital Costs and Outcomes?

Conditions:   Chest Pain;   Stable Angina;   Acute Coronary Syndrome;   Non ST Segment Elevation Acute Coronary Syndrome
Intervention:   Device: Routine Measurement of FFR
Sponsors:   University Hospital Southampton NHS Foundation Trust.;   Liverpool Heart and Chest Hospital NHS Foundation Trust
Not yet recruiting - verified September 2016

L-Citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects

Condition:   Acute Lung Injury
Interventions:   Drug: L-citrulline;   Other: Placebo
Sponsor:   Asklepion Pharmaceuticals, LLC
Recruiting - verified September 2016

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

Conditions:   B Acute Lymphoblastic Leukemia;   Bone Necrosis;   Central Nervous System Leukemia;   Cognitive Side Effects of Cancer Therapy;   Neurotoxicity Syndrome;   Pain;   Testicular Leukemia;   Therapy-Related Toxicity;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions:   Drug: Clofarabine;   Drug: Cyclophosphamide;   Drug: Cytarabine;   Drug: Dasatinib;   Drug: Dexamethasone;   Drug: Doxorubicin Hydrochloride;   Drug: Etoposide;   Drug: Hydrocortisone Sodium Succinate;   Other: Laboratory Biomarker Analysis;   Drug: Leucovorin Calcium;   Drug: Mercaptopurine;   Drug: Methotrexate;   Drug: Pegaspargase;   Drug: Prednisone;   Radiation: Radiation Therapy;   Drug: Thioguanine;   Drug: Vincristine Sulfate
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified August 2016

Geriatric-CO-mAnagement for Cardiology Patients in the Hospital

Conditions:   Geriatric Assessment;   Health Services for the Aged;   Cardiovascular Diseases;   Activities of Daily Living;   Delirium;   Frail Elderly;   Length of Stay
Intervention:   Other: Cardio-geriatric co-management
Sponsors:   Universitaire Ziekenhuizen Leuven;   Katholieke Universiteit Leuven
Recruiting - verified September 2016

A Case Control Study to Identify the Role of Epigenetic Regulation of Genes Responsible for Energy Metabolism and Mitochondrial Function in the Obesity Paradox in Cardiac Surgery

Condition:   C.Surgical Procedure; Cardiac
Sponsor:   University of Leicester
Not yet recruiting - verified June 2016

PGE1 as Additive Anticoagulant in ECMO-Therapy

Conditions:   Respiratory Distress Syndrome, Adult;   Extracorporeal Membrane Oxygenation
Interventions:   Drug: Alprostadil;   Drug: 0.9% sodium chloride solution
Sponsor:   Thomas Staudinger
Recruiting - verified September 2016

The Role of Gut Microbiota in Heart Failure and Pre-Heart Failure With Preserved Ejection Fraction

Condition:   Heart Failure
Interventions:   Other: Blood Sample;   Other: Stool Sample
Sponsor:   University of Florida
Not yet recruiting - verified September 2016

The National Myelodysplastic Syndromes (MDS) Study

Condition:   Myelodysplastic Syndromes (MDS)
Intervention:   Other: Therapeutic
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI)
Recruiting - verified June 2016

Bright Light Therapy Efficacy for Depressive Symptoms Following Cardiac Surgery or Acute Coronary Syndrome: Pilot Trial

Condition:   Depressive Symptoms Post Cardiac Surgery or Post Acute Coronary Syndrome
Interventions:   Device: Bright Light Therapy Lamp;   Device: Modified Dim Lamp
Sponsor:   McGill University
Recruiting - verified September 2016

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified September 2016

A Comparison of an Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent for Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome
Interventions:   Device: Orsiro;   Device: Xience
Sponsors:   University Hospital Inselspital, Berne;   University of Lausanne Hospitals
Recruiting - verified September 2016

Effects of Inspiratory Muscles Strengthening Among Coronary Patients on the Sleep Apnea Obstructive Syndrome

Conditions:   Sleep Apnea, Obstructive;   Acute Coronary Syndrome
Interventions:   Device: POWERbreathe Fitness Plus, (POWERbreathe International Ltd, UK) [Inspiratory muscles strengthening];   Other: Control
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting - verified September 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified September 2016

Examining How Acute Treatment Contributes to Variations in AMI Mortality Across the English NHS

Condition:   Myocardial Infarction
Intervention:   Other: Standard Hospital Care
Sponsor:   London School of Economics and Political Science
Active, not recruiting - verified September 2016

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Active, not recruiting - verified September 2016

Real Life Long-term Adherence to Ticagrelor After PCI for Acute Coronary Syndromes

Condition:   Acute Coronary Syndrome (ACS)
Intervention:   Drug: Ticagrelor
Sponsor:   IHF GmbH - Institut für Herzinfarktforschung
Recruiting - verified September 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified September 2016

Study of a Quality Improvement Toolkit in Kerala, India, Among Hospitals Treating Acute Coronary Syndrome Patients

Condition:   Acute Coronary Syndrome
Intervention:   Behavioral: Quality Improvement Toolkit
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified September 2016

Active Surveillance Research Program for the Assessment of the Safety and the Effectiveness of Linagliptin

Condition:   Diabetes Mellitus, Type 2
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified September 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified September 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Conditions:   Venous Thrombosis;   Pulmonary Embolism;   Atrial Fibrillation;   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Standard of care
Sponsor:   Bayer
Recruiting - verified September 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified September 2016

Preventing Stem Cell Transplant Complications With a Blood Separator Machine

Conditions:   MDS (Myelodysplastic Syndrome);   Myeloproliferative Disorder;   Lymphoma, Non-Hodgkin;   ALL (Acute B-Lymphoblastic Leukemia);   AML (Acute Meylogenous Leukemia
Intervention:   Device: Graft Manipulation (CD34+ Selection)
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   Children's Research Institute
Recruiting - verified September 2016

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab;   Drug: Placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified September 2016

Antiplatelet Therapy Guided by Thrombelastography in Patients With Acute Coronary Syndromes (TEGCOR Study)

Conditions:   Thrombosis;   Coronary Artery Disease
Interventions:   Drug: Prasugrel;   Drug: Clopidogrel
Sponsor:   Indiana University
Terminated - verified September 2016

TAKO-TSUBO Cardiomyopathy and Genetic

Conditions:   Tako-TSUBO Cardiomyopathy;   Acute Coronary Syndrome
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Fédération Française de Cardiologie
Completed - verified February 2016

Study to Develop a Non-invasive Marker for Monitoring Myocardial Fibrosis

Conditions:   Hypertrophic Cardiomyopathy;   Acute Coronary Syndrome
Intervention:   Radiation: 99mTc-NC100692
Sponsor:   Ottawa Heart Institute Research Corporation
Recruiting - verified September 2016

Systolic Blood Pressure Intervention Trial

Condition:   Hypertension
Interventions:   Other: Intensive control of SBP;   Other: Standard BP arm
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Institute on Aging (NIA);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Institute of Neurological Disorders and Stroke (NINDS);   Wake Forest Baptist Health
Active, not recruiting - verified September 2016

Cohort of Patients Infected by an Arbovirus

Conditions:   Fever;   Dengue;   Chikungunya;   Zika Virus
Interventions:   Other: biological sample collection;   Other: quality of life questionnaire EuroQol®;   Other: Health Assessment Questionnaire - MDHAQ and RAPID3
Sponsors:   University Hospital Center of Martinique;   Institut National de la Santé Et de la Recherche Médicale, France;   Clinique Antilles-Guyane
Recruiting - verified September 2016

Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE)

Conditions:   Acute Coronary Syndrome;   Chest Pain
Sponsor:   Kavitha Chinnaiyan
Completed - verified September 2016

Study of Women With Acute Coronary Syndromes and Nonobstructive Coronary Artery Disease

Condition:   Acute Coronary Syndromes
Interventions:   Procedure: Intravascular ultrasound;   Procedure: MRI
Sponsors:   New York University School of Medicine;   Doris Duke Charitable Foundation
Active, not recruiting - verified September 2016

Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study

Conditions:   Myocardial Infarction;   Angina, Unstable
Sponsors:   University Hospital, Basel, Switzerland;   Swiss National Science Foundation
Recruiting - verified September 2016

Michelangelo - Oasis 5

Condition:   Thromboembolism
Interventions:   Drug: Fondaparinux;   Drug: enoxaparin
Sponsors:   GlaxoSmithKline;   University of Chicago;   Organon;   Sanofi;   Duke University
Completed - verified September 2016

OASIS-6 : The Safety and Efficacy of Fondaparinux Versus Control Therapy in Patients With ST Segment Elevation Acute Myocardial Infarction

Condition:   Thromboembolism
Interventions:   Drug: fondaparinux - UFH not indicated;   Other: Control - UFH not indicated;   Drug: Fondaparinux - UFH indicated;   Drug: Control - UFH
Sponsors:   GlaxoSmithKline;   Sanofi
Completed - verified September 2016