Acute Coronary Syndrome

Clinical Trial Finder

Many patients with acute coronary syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Bioresorbable Polymer ORSIRO Versus Durable Polymer RESOLUTE ONYX Stents

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina Pectoris;   Acute Coronary Syndrome;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Orsiro;   Device: Resolute Onyx
Sponsor:   Thorax Centrum Twente
Not yet recruiting - verified July 2015

Assessment of Prospective CYP2C19 Genotype Guided Dosing of Anti-Platelet Therapy in Percutaneous Coronary Intervention

Conditions:   Acute Coronary Syndrome;   Cardiovascular Diseases
Intervention:   Genetic: CYP2C19 genotyping
Sponsor:   University of Pennsylvania
Recruiting - verified July 2015

Platelet Reactivity in Acute Non-disabling Cerebrovascular Events

Conditions:   Stroke;   Ischemic Attack, Transient
Interventions:   Drug: Ticagrelor and Acetylsalicylic acid;   Drug: Clopidogrel and Acetylsalicylic acid
Sponsors:   Ministry of Science and Technology of the People´s Republic of China;   Beijing Municipal Science & Technology Commission
Not yet recruiting - verified July 2015

Impact on Public HEalth of a Network in Acute Myocardial Infarction Care

Conditions:   Myocardial Infarction;   Acute Coronary Syndrome
Intervention:  
Sponsors:   Guillermo Aldama;    Santás. Álvarez.Melisa. M.D.;   Abugattás. de Torres. Juan Pablo. M.D.
Recruiting - verified July 2015

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Not yet recruiting - verified July 2015

Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCI

Conditions:   Myocardial Ischemia;   Coronary Artery Disease;   Endothelial Dysfunction
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsor:   University Hospital of Limerick
Recruiting - verified July 2015

The Role of Sleep Disordered Breathing in Heart Failure Admissions

Conditions:   Sleep Apnea Syndromes;   Heart Failure
Intervention:   Device: Adaptive Servo Ventilation
Sponsors:   Rami Khayat;   Philips Respironics
Active, not recruiting - verified July 2015

Low Level Laser Therapy in Heart Failure Patients.

Condition:   Heart Failure
Intervention:   Device: LASER
Sponsor:   Federal University of Health Science of Porto Alegre
Not yet recruiting - verified July 2015

TIcagrelor in Rotational Atherectomy to Reduce TROPonin Enhancement: the TIRATROP Study

Condition:   Atherosclerosis
Interventions:   Drug: ticagrelor;   Drug: clopidogrel
Sponsor:   University Hospital, Toulouse
Not yet recruiting - verified July 2015

Reevaluation Of Systemic Early Neuromuscular Blockade

Condition:   Acute Respiratory Distress Syndrome
Intervention:   Drug: cisastracurium besylate
Sponsors:   Massachusetts General Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified July 2015

Study of the Etiology and Immunological Pathogenesis in Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF)

Condition:   Interstitial Lung Diseases
Intervention:   Other: No intervention
Sponsor:   Shanghai Pulmonary Hospital, Shanghai, China
Enrolling by invitation - verified July 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified July 2015

Effects of Dexmedetomidine on Delirium After Living Donor Renal Transplantation in Adult Patients

Condition:   Postoperative Delirium After Living Donor Renal Transplantation
Interventions:   Drug: Dexmedetomidine;   Drug: Saline
Sponsor:   Tao Zhang
Recruiting - verified July 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified July 2015

Sub Lingual Versus Traditional Oral Administration of Ticagrelor in Acute Coronary Syndrome/Non ST-elevation Myocardial Infarction - A Platelet Reactivity Study

Conditions:   Acute Coronary Syndromes;   Non ST Elevation Myocardial Infarction
Intervention:   Drug: Sub Lingual Ticagrelor
Sponsor:   Sheba Medical Center
Recruiting - verified July 2015

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Conditions:   Coronary Artery Disease;   Atherosclerosis, Coronary;   Myocardial Ischemia;   Ischemic Heart Disease;   Acute Coronary Syndrome;   Angina Pectoris
Interventions:   Device: Orsiro DES;   Device: Xience DES
Sponsors:   Biotronik, Inc.;   Biotronik AG;   Harvard Clinical Research Institute;   Medstar Research Institute
Recruiting - verified June 2015

Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase II

Condition:   Acute Coronary Artery Syndrome
Interventions:   Procedure: Percutaneous coronary intervention;   Procedure: Intravascular ultrasound with virtual histology;   Drug: Atorvastatin or other equivalent dose statin;   Device: LDL-apheresis
Sponsor:   Department of Veterans Affairs
Recruiting - verified July 2015

Clinical Study Protocol - Debris Interventional Removal in ACS (DESIRE-ACS)

Conditions:   Coronary Disease;   Acute Coronary Syndrome;   Coronary Occlusion
Intervention:   Device: Bell Balloon Catheter
Sponsor:   Angioslide Ltd.
Recruiting - verified July 2015

CCC Project- Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   Beijing Institute of Heart, Lung and Blood Vessel Diseases;   American Heart Association;   Chinese Society of Cardiology
Recruiting - verified July 2015

Long-term Follow-up of antithrombotIc Management Patterns in Acute Coronary Syndrome Patients in Asia-China Extension

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Study of Ticagrelor Versus Aspirin Treatment in Patients With Myocardial Injury Post Major Non-cardiac Surgery

Condition:   Myocardial Injury
Interventions:   Drug: ticagrelor;   Drug: aspirin
Sponsors:   The Cleveland Clinic;   AstraZeneca
Recruiting - verified July 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Role of USCOM in Adult Patients With Heart Failure

Conditions:   Acute Decompensated Heart Failure;   Congestive Heart Failure Compensated
Interventions:   Device: Ultrasonic cardiac output monitor;   Device: Echocardiography
Sponsors:   Chinese University of Hong Kong;   Cardiff and Vale University Health Board;   University Hospitals, Leicester
Recruiting - verified July 2015

Randomized Comparison of Radiological Exposure With TRIPTable® in Patients With Acute Coronary Syndromes

Conditions:   Acute Coronary Syndromes;   Angioplasty, Transluminal, Percutaneous Coronary
Interventions:   Device: TripTable;   Device: Radial;   Device: Femoral
Sponsor:   Marilia Medicine School
Active, not recruiting - verified July 2015

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified July 2015

Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer

Conditions:   Rivaroxaban;   Cancer-associated Thrombosis;   Recurrence;   Bleeding
Intervention:   Drug: Rivaroxaban
Sponsors:   Seoul National University Hospital;   Korean Society of Hematology Thrombosis Working Party
Recruiting - verified July 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Acenocoumarol
Sponsor:   Bayer
Recruiting - verified July 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Phenprocoumon
Sponsor:   Bayer
Recruiting - verified July 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified July 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified July 2015

Anesthetic Methods and Liver Transplantation

Condition:   Acute Lung Injury
Interventions:   Drug: propofol during liver transplantation.;   Drug: Desflurane during liver transplantation.
Sponsor:   National Taiwan University Hospital
Recruiting - verified July 2015

Screening for Abdominal Aortic Aneurysm Using a Portable Transthoracic Echocardiography Among Patients With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   HaEmek Medical Center, Israel
Recruiting - verified July 2015

GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation

Condition:   Coronary Artery Disease (CAD)
Interventions:   Drug: Ticagrelor;   Drug: Acetylsalicylic Acid;   Drug: Clopidogrel
Sponsors:   ECRI bv;   Biosensors International;   AstraZeneca;   The Medicines Company
Recruiting - verified July 2015

Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)

Conditions:   Acute Coronary Syndrome;   Angina Pectoris;   Angina, Unstable;   Myocardial Infarction;   Coronary Artery Disease;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Orsiro;   Device: Synergy;   Device: Resolute Integrity
Sponsor:   Cardio Research Enschede BV
Enrolling by invitation - verified July 2015

DUrable Polymer-based STent CHallenge of Promus Element Versus ReSolute Integrity in an All Comers Population

Conditions:   Acute Coronary Syndrome;   Angina Pectoris;   Angina, Unstable;   Myocardial Infarction;   Coronary Artery Disease;   Coronary Stenosis;   Coronary Restenosis
Interventions:   Device: Resolute Integrity (Zotarolimus-eluting stent);   Device: Promus Element (Everolimus-eluting stent)
Sponsor:   Cardio Research Enschede BV
Completed - verified July 2015

Assessing Respiratory Variability During Mechanical Ventilation in Acute Lung Injury (ALI)

Conditions:   Acute Lung Injury;   Adult Respiratory Distress Syndrome
Intervention:  
Sponsor:   Boston Medical Center
Recruiting - verified July 2015

Endothelial Function and Heart Rate Variability After Stenting

Condition:   Restenosis or Adverse Cardiovascular Event
Intervention:   Device: stent implantation in coronary artery
Sponsor:   Helse Stavanger HF
Completed - verified October 2009

Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department

Conditions:   Acute Myocardial Infarction;   Chest Pain;   Acute Coronary Syndrome
Intervention:  
Sponsor:   Biosite
Withdrawn - verified July 2015

Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMAC

Conditions:   MDS;   Immunodeficiency;   GATA2
Interventions:   Drug: Cyclophosphamide (CTX, Cytoxan);   Drug: Fludarabine(Fludara,Berlex Laboratories);   Procedure: Total Body Irradiation (TBI);   Procedure: Allogeneic HSC;   Drug: Equine Anti-Thymocyte Globulin
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified July 2014

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

Conditions:   Anemia;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Previously Treated Myelodysplastic Syndrome
Interventions:   Biological: Epoetin Alfa;   Other: Laboratory Biomarker Analysis;   Drug: Lenalidomide
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified April 2015

Mortality Analysis of ST Elevation Myocardial Infarction (STEMI) Patients in Belgium

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsors:   Universiteit Antwerpen;   Belgian Government
Recruiting - verified July 2015

The Role of Sleep Apnea in the Acute Exacerbation of Heart Failure

Conditions:   Heart Failure;   Obstructive Sleep Apnea;   Heart Failure, Congestive
Intervention:   Device: CPAP Therapy
Sponsor:   Ohio State University
Active, not recruiting - verified July 2015

Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelopdysplastic Syndrome

Conditions:   Myelodysplastic Syndrome (MDS);   Severe Aplastic Anemia (SAA)
Interventions:   Other: Umbilical Cord Blood;   Other: Haploidentical Stem Cells;   Device: Miltenvi CliniMACs CD34 Reagent System
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified June 2015

Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignances

Conditions:   Immunosuppression;   Leukemia
Intervention:   Device: SOLEX 300i Stem Cell Selection
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified June 2015

Rapid Assessment of Cardiac Markers for the Evaluation of Acute Coronary Syndrome (RACE-ACS)

Condition:   Acute Coronary Syndrome
Intervention:   Device: Triage CardioProfilER (Troponin I, Myoglobin, CK-MB, BNP)
Sponsor:   Biosite
Withdrawn - verified July 2015

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