Acute Coronary Syndrome

Clinical Trial Finder

Many patients with acute coronary syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Attentional Capacity and Working Memory in Coronary Artery Disease Patients: Impact of the Presence of a Sleep Apnea Syndrome and Chronic Effects of Treatment With CPAP

Conditions:   Obstructive Sleep Apnea;   Acute Coronary Syndrome
Intervention:   Device: CPAP treatment
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Recruiting - verified August 2015

Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery

Conditions:   Hypotension;   Postoperative Complications;   Acute Coronary Syndrome;   Heart Failure;   Coronary Occlusion;   Stroke;   Acute Kidney Injury;   Renal Insufficiency, Chronic;   Death
Interventions:   Drug: Liberal blood pressure management;   Drug: Tight blood pressure management
Sponsor:   Miodrag Filipovic, Prof. Dr. med.
Not yet recruiting - verified August 2015

A Trial Evaluating Methods to Use Physical Activity to Improve Outcomes After Hospitalization for Acute Coronary Syndrome

Conditions:   Physical Activity;   Acute Coronary Syndrome
Interventions:   Behavioral: Financial-incentive based physical activity program;   Device: "Misfit Shine" Wearable Activity Tracking Device
Sponsor:   University of Pennsylvania
Not yet recruiting - verified August 2015

Evaluation of Rapid Emergency Echography for Acute Dyspnoea

Condition:   Acute Dyspnea
Intervention:   Device: Echocardiography according to the READ method.
Sponsors:   Centre Hospitalier Universitaire de Besancon;   Centre Hospitalier Germon et Gauthier;   University Hospital, Clermont-Ferrand;   Centre Hospitalier de PAU;   Centre Hospitalier Universitaire de Strasbourg;   Centre Hospitalier Général de Toulon
Not yet recruiting - verified August 2015

Comparison of Ticagrelor vs. Prasugrel on Inflammation, Arterial Stiffness, Endothelial Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Coronary Stenting

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Ticagrelor;   Drug: Prasugrel
Sponsors:   Korea University Anam Hospital;   AstraZeneca
Recruiting - verified August 2015

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Recruiting - verified August 2015

Peri-operative Monitoring of Cerebral Oxygenation and the Onset of Delirium in Patients Undergoing Cardiac Surgery

Condition:   Delirium
Intervention:   Device: Near-Infrared Spectroscopy (NIRS)
Sponsors:   Hasselt University;   Ziekenhuis Oost-Limburg
Recruiting - verified August 2015

Increased Adsorption Membranes During Cardiopulmonary Bypass

Conditions:   Cardiopulmonary Bypass;   Acute Kidney Injury;   Systemic Inflammatory Response Sydrome
Intervention:   Device: OXIRIS®
Sponsor:   Hospital Universitari de Bellvitge
Not yet recruiting - verified August 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural Medical University ;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified August 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Recruiting - verified August 2015

An Observational Prospective Study to Understand the Usage Pattern of Ticagrelor With ACS (Acute Coronary Syndrome)

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Clinical Trial to Evaluate the Use of an Adsorption Membrane (OXIRIS®) During Cardiopulmonary Bypass Surgery

Conditions:   Cardiac Surgical Procedures;   Cardiopulmonary Bypass
Intervention:   Device: OXIRIS®
Sponsors:   Hospital Universitari de Bellvitge;   Gambro Renal Products, Inc.
Recruiting - verified May 2015

Long-term Follow-up of antithrombotIc Management Patterns in Acute Coronary Syndrome Patients in Asia-China Extension

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified August 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Left Bundle Branch Block ECG Characteristics in the Evaluation of Acute Coronary Syndrome

Condition:   Left Bundle Branch Block
Intervention:   Other: None - no intervention, observational study
Sponsor:   Duke University
Terminated - verified August 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Time-motion-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in Emergency Department

Condition:   Respiratory Distress Syndrome, Adult
Intervention:   Device: Vivid S6 GE Ultrasound
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Recruiting - verified August 2015

Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.

Condition:   Acute Coronary Syndrome
Interventions:   Drug: MEOPA and paracetamol;   Drug: Morphine
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2015

Active Surveillance Research Program for the Assessment of the Safety and the Effectiveness of Linagliptin

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified August 2015

Phase I/II Trial of Early Infusion of Multivirus Specific T Cells (MVST) to Prevent Post Transplant Viral Infections

Conditions:   Chronic Lymphocytic Leukemia;   CML (Chronic Myelogenous Leukemia);   MDS (Myelodysplastic Syndrome);   Acute Lymphoblastic Leukemia;   AML (Acute Myelogenous Leukemia)
Intervention:   Biological: MVST
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Suspended - verified June 2015

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified August 2015

Precision of IMED-4 Lung Fluid Measurements

Conditions:   Dyspnea;   Acute Heart Failure Syndrome;   Pulmonary Congestion
Intervention:   Device: IMED-4
Sponsor:   Intersection Medical, Inc.
Recruiting - verified August 2015

Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Intervention:   Other: blood sample
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting - verified August 2015

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Treatment 90 days DAPT;   Drug: Treatment 360 days DAPT
Sponsor:   Diagram B.V.
Recruiting - verified August 2015

Use of Abbott High Sensitivity Troponin I Assay In Acute Coronary Syndromes

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction;   Troponin
Intervention:  
Sponsors:   Minneapolis Medical Research Foundation;   Abbott Diagnostics Division;   Hennepin County Medical Center, Minneapolis
Active, not recruiting - verified August 2015

Aspirin Impact on Platelet Reactivity in Acute Coronary Syndrome Patients on Novel P2Y12 Inhibitors Therapy

Conditions:   Acute Coronary Syndrome;   Platelet Function and Reactivity Tests;   Novel P2Y12 Inhibitors
Intervention:   Drug: Aspirin
Sponsor:   Sheba Medical Center
Recruiting - verified August 2015

Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO

Conditions:   Acute Respiratory Distress Syndrome;   Acute Cor Pulmonale
Intervention:   Other: High Frequency Oscillation
Sponsor:   University of Athens
Recruiting - verified August 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified August 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Acenocoumarol
Sponsor:   Bayer
Recruiting - verified August 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Phenprocoumon
Sponsor:   Bayer
Recruiting - verified August 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

The GReek AntiPlatElet (GRAPE) Registry: A Multicenter Observational Prospective Investigation of Antiplatelet Treatment in Patients With Acute Coronary Syndrome Subjected to Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsors:   University of Patras;   Hellenic Cardiological Society
Completed - verified August 2015

Detection of Right Ventricular Dysfunction by 2D Strain During Acute Respiratory Distress Syndrom (ARDS)

Conditions:   Acute Respiratory Distress Syndrome;   Right Ventricular Dysfunction;   Right Heart Failure;   Acute Cor Pulmonale
Intervention:  
Sponsor:   University Hospital, Grenoble
Recruiting - verified August 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified August 2015

Controlled Level EVERolimus in Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Everolimus;   Drug: Placebo
Sponsors:   University of Zurich;   Swiss National Science Foundation;   Novartis
Recruiting - verified August 2015

TAKO-TSUBO Cardiomyopathy and Genetic

Conditions:   Tako-TSUBO Cardiomyopathy;   Acute Coronary Syndrome
Intervention:  
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Fédération Française de Cardiologie
Active, not recruiting - verified August 2015

IVUS Assessment of Atheroma Burden After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   University Hospital, Toulouse
Recruiting - verified August 2015

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Aleglitazar;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

Genetic Variability and Biomarkers in Children With Acute Lung Injury

Conditions:   Acute Respiratory Distress Syndrome;   Acute Lung Injury
Intervention:  
Sponsors:   Medical College of Wisconsin;   National Heart, Lung, and Blood Institute (NHLBI);   Children's Hospital & Research Center Oakland;   University of California, San Francisco
Withdrawn - verified August 2015

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

Conditions:   Anemia;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Previously Treated Myelodysplastic Syndrome
Interventions:   Biological: Epoetin Alfa;   Other: Laboratory Biomarker Analysis;   Drug: Lenalidomide
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified April 2015

High Cut-Off Continuous Veno-venous Hemodialysis (CVVHD) in Patients Treated for Acute Renal Failure After Systemic Inflammatory Response Syndrome (SIRS)/Septic Shock

Conditions:   Systemic Inflammatory Response Syndrome;   Kidney Failure, Acute
Intervention:   Device: continuous venovenous hemodialysis
Sponsor:   Gambro Dialysatoren GmbH
Terminated - verified January 2010

Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina;   Acute Coronary Syndrome
Interventions:   Procedure: Coronary Computed Tomography Angiography;   Procedure: Stress Nuclear Myocardial Perfusion Imaging
Sponsors:   Montefiore Medical Center;   American Heart Association;   Albert Einstein College of Medicine of Yeshiva University
Completed - verified August 2015

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Condition:   Coronary Heart Disease
Interventions:   Drug: Evidence-based medical care for Acute Coronary Syndrome;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified August 2015

Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi Anemia

Conditions:   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Childhood Acute Myeloid Leukemia in Remission;   Childhood Myelodysplastic Syndromes;   de Novo Myelodysplastic Syndromes;   Fanconi Anemia;   Previously Treated Myelodysplastic Syndromes
Interventions:   Drug: fludarabine phosphate;   Drug: cyclophosphamide;   Radiation: total-body irradiation;   Procedure: allogeneic bone marrow transplantation;   Drug: mycophenolate mofetil;   Drug: cyclosporine;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Other: laboratory biomarker analysis
Sponsors:   Fred Hutchinson Cancer Research Center;   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI)
Active, not recruiting - verified August 2015

Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

Conditions:   Lymphoma;   Leukemia;   Myeloproliferative Disorders;   Multiple Myleoma;   Myelodysplastic Syndrome
Interventions:   Drug: Rituximab;   Drug: Fludarabine;   Drug: Cyclosporine;   Drug: Etoposide;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Cyclophosphamide;   Biological: T-Rapa cell DLI;   Procedure: T cell DLI;   Drug: Prednisone;   Procedure: Allogeneic HSCT;   Drug: Filgrastim
Sponsor:   National Cancer Institute (NCI)
Suspended - verified September 2014

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

Conditions:   Hematologic Disease;   Lymphoma;   Multiple Myeloma;   Myelodysplastic Syndrome;   Myeloproliferative Disorder
Intervention:   Procedure: Stem cell transplantation
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2015

Bone Marrow Transplant Studies for Safe and Effective Treatment of Leukemia

Conditions:   Graft vs Host Disease;   Hematologic Neoplasm;   Leukemia;   Multiple Myeloma;   Myelodysplastic Syndrome
Intervention:   Procedure: Allogeneic Bone Marrow Transplant
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified August 2015

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