Acute Coronary Syndrome

Clinical Trial Finder

Many patients with acute coronary syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Early Invasive Versus Conservative Therapy in Women With an Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Procedure: coronary angiography;   Procedure: adenosine stress test
Sponsor:   University of Florida
Completed - verified February 2015

ART-2 Pilot - Driving Pressure Limited Ventilation for Patients With ARDS

Condition:   Acute Respiratory Distress Syndrome
Interventions:   Other: Driving pressure limited ventilation;   Other: Conventional ventilation
Sponsor:   Hospital do Coracao
Not yet recruiting - verified February 2015

The Role of Gut Microbiota in Hypertension

Condition:   Hypertension
Intervention:   Other: Stool Sample and Blood Sample
Sponsor:   University of Florida
Recruiting - verified February 2015

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Conditions:   Atrial Fibrillation;   Percutaneous Coronary Intervention
Interventions:   Drug: Dabigatran Etexilate 110mg;   Drug: Warfarin 3mg;   Drug: Aspirin;   Drug: Dabigatran Etexilate 150mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 5mg;   Drug: Clopidogrel or Ticagrelor;   Drug: Warfarin 1mg
Sponsor:   Boehringer Ingelheim
Recruiting - verified February 2015

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Losmapimod 7.5 mg twice daily;   Drug: Placebo twice daily
Sponsors:   GlaxoSmithKline;   The TIMI Study Group
Recruiting - verified February 2015

Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-of-Care Setting

Condition:   Congestive Heart Failure
Intervention:   Device: Samsung LABGEO IVD-A20 CHF Test
Sponsors:   Samsung Electronics;   Nexus-Dx
Terminated - verified February 2015

Ticagrelor vs Clopidogrel in Non-ST Elevation Acute Coronary Syndrome Patients Undergoing PCI With Bivalirudin.

Condition:   Non-ST Elevation Acute Coronary Syndrome
Interventions:   Drug: ticagrelor;   Drug: clopidogrel
Sponsor:   AstraZeneca
Recruiting - verified February 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Warfarin
Sponsor:   Bayer
Recruiting - verified February 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxoban (Xarelto, Bay59-7939);   Drug: Acenocoumarol
Sponsor:   Bayer
Recruiting - verified February 2015

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Germany)

Condition:   Pulmonary Embolism
Interventions:   Drug: Rivaroxaban (Xarelto, Bay59-7939);   Drug: Phenprocoumon
Sponsor:   Bayer
Recruiting - verified February 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified February 2015

Renal Denervation in Patients After Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Arterial Hypertension
Interventions:   Procedure: Renal denervation;   Drug: Metoprolol;   Drug: Lisinopril
Sponsor:   Meshalkin Research Institute of Pathology of Circulation
Recruiting - verified February 2015

Treosulfan and Fludarabine Phosphate With or Without Total Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Conditions:   Adult Acute Myeloid Leukemia in Remission;   Childhood Acute Myeloid Leukemia in Remission;   Childhood Myelodysplastic Syndrome;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Minimal Residual Disease;   Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable;   Previously Treated Myelodysplastic Syndrome
Interventions:   Drug: Treosulfan;   Drug: Fludarabine Phosphate;   Radiation: Total-Body Irradiation;   Procedure: Peripheral Blood Stem Cell Transplantation;   Procedure: Allogeneic Bone Marrow Transplantation;   Other: Laboratory Biomarker Analysis
Sponsors:   Fred Hutchinson Cancer Research Center;   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI)
Recruiting - verified February 2015

Canadian Ticagrelor Survey

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Completed - verified February 2015

The Impact of Gratitude on Biology and Behavior in Persons With Heart Disease

Conditions:   Myocardial Infarction;   Unstable Angina
Intervention:  
Sponsors:   Massachusetts General Hospital;   University of California, Berkeley
Completed - verified February 2015

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab SAR236553 (REGN727)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Other: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified February 2015

EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures

Condition:   Acute Respiratory Distress Syndrome
Interventions:   Other: Esophageal-pressure guided mechanical ventilation;   Other: High PEEP mechanical ventilation
Sponsors:   Beth Israel Deaconess Medical Center;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified February 2015

Tryptase and Coronary Heart Disease

Conditions:   Acute Coronary Syndrome With ST Elevation on Electrocardiogram;   Acute Coronary Syndrome Without ST Elevation on Electrocardiogram;   Noncritical Coronary Artery Disease With Coronary Stenosis <50%;   Aortic Aneurysms
Intervention:  
Sponsor:   Niguarda Hospital
Recruiting - verified February 2015

Tailored Antiplatelet Therapy Versus Recommended Dose of Prasugrel

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Modification of Prasugrel based on a biological assay;   Drug: prasugrel / clopidogrel;   Device: Verify Now
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Eli Lilly and Company;   Daiichi Sankyo Inc.;   Allies in Cardiovascular Trials Initiatives and Organized Networks:ACTION;   Accumetrics, Inc.;   Stentys
Recruiting - verified February 2015

Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention

Conditions:   Myocardial Infarction;   Acute Coronary Syndromes;   Unstable Angina
Interventions:   Drug: Short Tirofiban;   Drug: Eptifibatide;   Drug: Long Tirofiban
Sponsors:   Medicure;   SCRI Development Innovations, LLC
Recruiting - verified February 2015

The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury

Condition:   Lung Injury, Acute
Interventions:   Drug: Dose 1 GSK2586881;   Drug: Dose 2 GSK2586881;   Drug: Dose 3 GSK2586881;   Drug: Dose 4 GSK2586881;   Drug: Placebo (saline)
Sponsor:   GlaxoSmithKline
Completed - verified February 2015

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Conditions:   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Previously Treated Myelodysplastic Syndrome;   Refractory Anemia With Excess Blasts;   Secondary Myelodysplastic Syndrome
Interventions:   Drug: Azacitidine;   Drug: Lenalidomide;   Drug: Vorinostat
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified November 2014

French Registry of Acute Coronary Syndrome With or Without ST Elevation 2010

Conditions:   Myocardial Infarction;   Acute Coronary Syndrome
Intervention:  
Sponsor:   French Cardiology Society
Active, not recruiting - verified February 2015

Imaging and Biomarkers of Atherosclerosis in Patients With Stable or Unstable Coronary Artery Disease

Conditions:   Atherosclerosis;   Coronary Artery Disease;   Acute Coronary Syndrome
Interventions:   Device: Coronary intervention using IVUS-VH & FDG PET-MDCT;   Device: Coronary intervention using IVUS-VH & FDG PET-MDCT
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Institut National de la Santé Et de la Recherche Médicale, France
Completed - verified February 2015

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

Conditions:   Anemia;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Previously Treated Myelodysplastic Syndrome
Interventions:   Drug: Lenalidomide;   Biological: Epoetin Alfa;   Other: Laboratory Biomarker Analysis
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified November 2014

French Registry of Acute Coronary Syndrome

Condition:   Acute Myocardial Infarction
Intervention:   Other: Blood sample
Sponsors:   Assistance Publique - Hôpitaux de Paris;   French Cardiology Society
Active, not recruiting - verified October 2014

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Condition:   Coronary Heart Disease
Interventions:   Drug: Evidence-based medical care for Acute Coronary Syndrome;   Drug: Placebo;   Drug: dalcetrapib
Sponsor:   Hoffmann-La Roche
Completed - verified February 2015

Role of Placenta Growth Factor in Sickle Acute Chest Syndrome

Condition:   Anemia, Sickle Cell
Intervention:  
Sponsors:   Children's Hospital Medical Center, Cincinnati;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified January 2014

Eligibility Screening for a NCI Pediatric Oncology Branch Research Study

Conditions:   Ewing Sarcoma;   Osteosarcoma;   Neuroblastoma;   Acute Lymphoblastic Leukemia;   Neurofibromatosis Type 1
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Enrolling by invitation - verified February 2015

Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults

Conditions:   Chronic Lymphocytic Leukemia;   Graft vs Host Disease;   Leukemia;   Myelodysplastic Syndrome;   Myeloid Leukemia
Intervention:   Procedure: Blood cell transplantation
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified January 2015

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