Acute Coronary Syndrome

Clinical Trial Finder

Many patients with acute coronary syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

An Epidemiological Cohort Study of Acute Coronary Syndromes in The Greek Population. The PHAETHON Study

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Hellenic Cardiovascular Research Society
Completed - verified April 2015

Different Doses of Rosuvastatin Therapy on Regression of Critical Coronary Atherosclerosis in ACS Patients

Condition:   Acute Coronary Syndrome
Intervention:   Drug: rosuvastatin
Sponsor:   Beijing Friendship Hospital
Not yet recruiting - verified April 2015

Study Apixaban to Vitamin K Antagonist for the Prevention of Stroke or Systemic Embolism and Bleeding in Patients With Non-valvular Atrial Fibrillation and Acute Coronary Syndrome/Percutaneous Coronary Intervention

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Apixaban;   Drug: vitamin K antagonist;   Drug: Acetylsalicylic acid;   Other: Acetylsalicylic acid placebo
Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke Clinical Research Institute
Not yet recruiting - verified April 2015

Researches of Retinal Artery Lesions and Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Capital Medical University
Active, not recruiting - verified April 2015

Safety and Efficacy of Low-Dose Ticagrelor in Chinese Patients With NSTE-ACS

Condition:   Non ST Segment Elevation Acute Coronary Syndrome
Interventions:   Drug: low-dose ticagrelor;   Drug: conventional-dose ticagrelor;   Drug: Clopidogrel
Sponsor:   First Affiliated Hospital of Harbin Medical University
Recruiting - verified December 2014

Risk Factors of Postoperative Acute Lung Injury Following Liver Transplantation

Condition:   Acute Lung Injury
Intervention:  
Sponsor:   National Taiwan University Hospital
Recruiting - verified April 2015

Dose-escalation, Repeated and Single Oral Dosing Study

Condition:   Acute Coronary Syndrome
Interventions:   Drug: APD791;   Drug: Clopidogrel;   Drug: Aspirin;   Drug: Placebo for APD791
Sponsors:   IlDong Pharmaceutical Co Ltd;   Asan Medical Center
Enrolling by invitation - verified April 2015

Trans-pulmonary Pressure in ARDS

Condition:   Acute Respiratory Distress Syndrome
Interventions:   Device: level of positive end expiratory pressure (Prone Proseva);   Device: level of positive end expiratory pressure (Prone Talmor)
Sponsor:   Hospices Civils de Lyon
Not yet recruiting - verified April 2015

Jakarta Acute Coronary Syndrome Registry

Condition:   Acute Coronary Syndrome
Intervention:   Other: JAC Registry
Sponsor:   National Cardiovascular Center Harapan Kita Hospital Indonesia
Recruiting - verified April 2015

Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Conditions:   Myelodysplastic Syndrome;   Hodgkin's Lymphoma;   Non-Hodgkin's Lymphoma;   Acute Leukemia;   Multiple Myeloma
Interventions:   Biological: Rituximab;   Drug: Conditioning Chemotherapy;   Drug: TMS;   Drug: FLAG;   Drug: EPOCH-F;   Procedure: Hematopoietic Stem Cell Transplant;   Drug: Palifermin
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified January 2015

Long-term Follow-up of antithrombotIc Management Patterns in Acute Coronary Syndrome Patients in Asia-China Extension

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified April 2015

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Not yet recruiting - verified April 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   AstraZeneca
Not yet recruiting - verified April 2015

Active Surveillance Research Program for the Assessment of the Safety and the Effectiveness of Linagliptin

Condition:   Diabetes Mellitus, Type 2
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2015

Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

Conditions:   Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Acute Biphenotypic Leukemia;   Acute Leukemia of Ambiguous Lineage;   Acute Undifferentiated Leukemia;   Adult Acute Lymphoblastic Leukemia in Remission;   Adult Acute Myeloid Leukemia in Remission;   Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Childhood Acute Lymphoblastic Leukemia in Remission;   Childhood Acute Myeloid Leukemia in Remission;   Graft Versus Host Disease;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Childhood Acute Lymphoblastic Leukemia;   Recurrent Childhood Acute Myeloid Leukemia;   Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Refractory Anemia With Excess Blasts
Interventions:   Radiation: Total-Body Irradiation;   Drug: Fludarabine Phosphate;   Drug: Thiotepa;   Drug: Cyclophosphamide;   Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;   Procedure: Peripheral Blood Stem Cell Transplantation;   Procedure: Peripheral Blood Stem Cell Transplantation;   Drug: Tacrolimus;   Drug: Methotrexate;   Drug: Mycophenolate Mofetil;   Other: Laboratory Biomarker Analysis
Sponsors:   Fred Hutchinson Cancer Research Center;   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI)
Recruiting - verified April 2015

Osteopathic Treatment and Deep Vein Thrombosis (DVT)

Condition:   Deep Vein Thrombosis (DVT)
Intervention:   Other: Osteopathic Treatment
Sponsor:   Capital District Health Authority, Canada
Recruiting - verified April 2015

Incremental Value of Point of Care H-FABP Testing in Primary Care Patients Suspected of Acute Coronary Syndrome

Conditions:   Acute Coronary Syndrome;   Angina Pectoris, Unstable;   Angina Pectoris, Stable;   Thoracic Diseases
Intervention:   Device: heart type fatty acid binding protein testing
Sponsors:   Maastricht University Medical Center;   FABPulous B.V.
Recruiting - verified April 2015

Preventing Stem Cell Transplant Complications With a Blood Separator Machine

Conditions:   MDS (Myelodysplastic Syndrome);   Myeloproliferative Disorder;   Lymphoma, Non-Hodgkin;   ALL (Acute B-Lymphoblastic Leukemia);   AML (Acute Meylogenous Leukemia
Intervention:   Device: Graft Manipulation (CD34+ Selection)
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2015

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab SAR236553 (REGN727)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Other: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified April 2015

Non-Invasive Ventilation Preoperative Lung Resection Surgery

Condition:   Surgery for Primary Lung Cancer
Intervention:   Device: Manufacturer (VPAP ST)
Sponsors:   University Hospital, Brest;   Ministry of Health, France
Recruiting - verified April 2015

The Supplementary Role of Non-invasive Imaging to Routine Clinical Practice in Suspected Non-ST-elevation Myocardial Infarction

Conditions:   Chest Pain;   Myocardial Infarction;   Acute Coronary Syndrome;   Coronary Artery Disease;   Myocardial Ischemia
Interventions:   Other: Cardiovascular Magnetic Resonance Imaging;   Other: Computed Tomography Angiography
Sponsors:   Maastricht University Medical Center;   Dutch Heart Foundation
Recruiting - verified April 2015

Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum

Conditions:   Left Ventricular Dysfunction;   Cardiac Conduction Defect;   Heart Failure;   Sick Sinus Syndrome
Intervention:   Device: Left ventricular septum pacing lead
Sponsors:   Maastricht University Medical Center;   Medtronic Bakken Research Center
Recruiting - verified April 2015

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Conditions:   Adult Myelodysplastic Syndrome;   Chronic Myelomonocytic Leukemia;   Chronic Myelomonocytic Leukemia-1;   Chronic Myelomonocytic Leukemia-2;   Previously Treated Myelodysplastic Syndrome;   Refractory Anemia With Excess Blasts
Interventions:   Drug: Azacitidine;   Drug: Lenalidomide;   Drug: Vorinostat
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified March 2015

Fondaparinux EU-RMP (Adherence)

Conditions:   ST-elevation Myocardial Infarction;   Unstable Angina;   Non ST Segment Elevation Myocardial Infarction;   Acute Coronary Syndrome
Intervention:   Drug: fondaparinux
Sponsor:   GlaxoSmithKline
Completed - verified April 2015

Pharmacodynamic Study on Efficacy of Clopidogrel With St. John's Wort

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Placebo;   Drug: St. Johns Wort
Sponsors:   Lancaster General Hospital;   H. G. Barsumian Memorial Fund;   Louise von Hess Medical Research Institute
Terminated - verified April 2015

Aggrastat Truncated Length Against Standard Therapies in Percutaneous Coronary Intervention

Conditions:   Myocardial Infarction;   Acute Coronary Syndromes;   Unstable Angina;   Percutaneous Coronary Intervention
Interventions:   Drug: Tirofiban (Aggrastat);   Drug: Placebo
Sponsors:   Medicure;   SCRI Development Innovations, LLC
Suspended - verified April 2015

Study to Develop a Non-invasive Marker for Monitoring Myocardial Fibrosis

Conditions:   Hypertrophic Cardiomyopathy;   Acute Coronary Syndrome
Intervention:   Radiation: 99mTc-NC100692
Sponsor:   Ottawa Heart Institute Research Corporation
Active, not recruiting - verified April 2015

Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis

Conditions:   Aortocoronary Saphenous Vein Bypass Graft Atherosclerosis;   Intermediate Saphenous Vein Graft Lesions
Intervention:   Drug: extended-release niacin (Niaspan)
Sponsors:   North Texas Veterans Healthcare System;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified April 2015

Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft Angioplasty

Condition:   Saphenous Vein Graft Atherosclerosis
Interventions:   Device: Bare Metal Stent;   Device: Drug-Eluting Stent;   Drug: Blinded clopidogrel;   Drug: Placebo;   Drug: Thienopyridine (open-label)
Sponsor:   Department of Veterans Affairs
Recruiting - verified April 2015

Study Comparing CT Scan and Stress Test in Patients With Known Coronary Artery Disease Hospitalized for Chest Pain

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina;   Acute Coronary Syndrome
Interventions:   Procedure: Coronary CT angiography;   Procedure: Myocardial perfusion imaging
Sponsors:   Montefiore Medical Center;   Albert Einstein College of Medicine of Yeshiva University
Terminated - verified April 2015

Troponin T as Risk Stratification Tool in Peripheral Arterial Occlusive Disease

Condition:   Peripheral Arterial Occlusive Disease
Intervention:  
Sponsors:   Heart Center Bad Krozingen;   Johann Wolfgang Goethe University Hospitals
Completed - verified April 2015

A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)

Conditions:   Myelodysplastic Syndromes;   Thrombocytopenia
Intervention:   Drug: Eltrombopag
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified March 2015

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

Conditions:   Anemia;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Previously Treated Myelodysplastic Syndrome
Interventions:   Biological: Epoetin Alfa;   Other: Laboratory Biomarker Analysis;   Drug: Lenalidomide
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified April 2015

Evaluation of Varenicline (Champix) in Smoking Cessation for Patients Post-Acute Coronary Syndrome (EVITA) Trial

Condition:   Acute Coronary Syndrome
Interventions:   Drug: varenicline;   Other: placebo
Sponsors:   Mark Eisenberg;   St. Michael's Hospital, Toronto;   Sunnybrook Health Sciences Centre;   Queen Elizabeth II Health Sciences Centre
Active, not recruiting - verified April 2015

Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain

Conditions:   Coronary Artery Disease;   Angina Pectoris;   Unstable Angina;   Acute Coronary Syndrome
Interventions:   Procedure: Coronary Computed Tomography Angiography;   Procedure: Stress Nuclear Myocardial Perfusion Imaging
Sponsors:   Montefiore Medical Center;   American Heart Association;   Albert Einstein College of Medicine of Yeshiva University
Completed - verified April 2015

Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission

Conditions:   Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome;   Adult Acute Megakaryoblastic Leukemia;   Adult Acute Monocytic Leukemia;   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11;   Adult Acute Myeloid Leukemia With Maturation;   Adult Acute Myeloid Leukemia With Minimal Differentiation;   Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11;   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1;   Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL;   Adult Acute Myeloid Leukemia Without Maturation;   Adult Acute Myelomonocytic Leukemia;   Adult Erythroleukemia;   Adult Pure Erythroid Leukemia;   Alkylating Agent-Related Acute Myeloid Leukemia;   Recurrent Adult Acute Myeloid Leukemia;   Refractory Anemia With Excess Blasts in Transformation
Interventions:   Procedure: Clinical Observation;   Drug: Tipifarnib
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified December 2014

Extracorporeal Carbon Dioxide Removal for Acute Respiratory Distress Syndrome

Conditions:   Acute Respiratory Distress Syndrome;   Lung Diseases
Interventions:   Procedure: positive-pressure ventilation;   Procedure: extracorporeal membrane oxygenation (CO2 removal)
Sponsors:   Intermountain Health Care, Inc.;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2015

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