Acute Coronary Syndrome

Clinical Trial Finder

Many patients with acute coronary syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Anticoagulants Comparative Benefit-risk Ratio in Real Life

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Completed - verified May 2016

Association Between Telomere Length and Risk of Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Intervention:  
Sponsor:   Fourth Military Medical University
Completed - verified May 2016

Intracoronary Thrombus Detection by Magnetic Resonance Imaging

Conditions:   Angina Pectoris;   Angina, Stable;   Angina, Unstable;   Myocardial Infarction
Interventions:   Other: Magnetic Resonance Imaging;   Device: Optical Coherence Tomography;   Procedure: Invasive Coronary Angiography
Sponsor:   University of Edinburgh
Not yet recruiting - verified March 2016

Positive Psychology for ACS Patients: a Factorial Design Study

Condition:   Acute Coronary Syndrome
Interventions:   Other: Positive Psychology (PP);   Other: Motivational Interviewing (MI)
Sponsors:   Massachusetts General Hospital;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Prophylactic Non-invasive Ventilation During Surgical Procedure in Rhythmology

Conditions:   Cardiac Electrophysiology;   Anesthesia;   Acute Respiratory Failure
Interventions:   Other: non invasive ventilation;   Other: Standard oxygen therapy with facial mask
Sponsor:   University Hospital, Grenoble
Not yet recruiting - verified May 2016

The National Myelodysplastic Syndromes (MDS) Study

Condition:   Myelodysplastic Syndromes (MDS)
Intervention:   Other: Therapeutic
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI)
Recruiting - verified April 2016

Small Volume Plasma Exchange (SVPE) for Guillain-Barré Syndrome (GBS) Patients

Condition:   Guillain-Barré Syndrome
Intervention:   Procedure: Small Volume Plasma Exchange
Sponsors:   International Centre for Diarrhoeal Disease Research, Bangladesh;   GBS-CIDP Foundation International;   National Institute of Neuroscience, Dhaka, Bangladesh;   Erasmus Medical Center
Recruiting - verified May 2016

A Randomised Controlled Trial of High-Flow Nasal Oxygen Versus Standard Oxygen Therapy in Critically Ill Immunocompromised Patients

Condition:   Acute Respiratory Failure
Interventions:   Procedure: standard oxygen;   Procedure: HFNO
Sponsor:   Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified March 2016

"Me and My Heart" Study

Condition:   Acute Coronary Syndrome
Interventions:   Device: Active group with MEMS;   Device: Active group without MEMS;   Device: Control group with MEMS;   Device: Control group without MEMS
Sponsor:   AstraZeneca
Recruiting - verified May 2016

Northera Improves Postural Tachycardia Syndrome (POTS) and Postural Vasovagal Syncope (VVS)

Conditions:   Postural Tachycardia Syndrome (POTS);   Vasovagal Syncope (VVS);   Fainting
Interventions:   Drug: Northera (Droxidopa);   Drug: Placebo;   Drug: Northera (Droxidopa);   Drug: Placebo
Sponsors:   New York Medical College;   Lundbeck LLC
Recruiting - verified May 2016

Platelet Reactivity in Acute Non-disabling Cerebrovascular Events

Conditions:   Stroke;   Ischemic Attack, Transient
Interventions:   Drug: Ticagrelor and Acetylsalicylic acid;   Drug: Clopidogrel and Acetylsalicylic acid
Sponsors:   Ministry of Science and Technology of the People´s Republic of China;   Beijing Municipal Science & Technology Commission
Recruiting - verified May 2016

Platelet REactivity in Sepsis Syndrome (PRESS)

Condition:   Sepsis Syndrome
Intervention:  
Sponsors:   Charalambos .A. Gogos;   Hellenic Society for Chemotherapy : Hellenic Sepsis Study Group;   University Hospital of Patras
Active, not recruiting - verified May 2016

CER-001 Atherosclerosis Regression ACS Trial

Condition:   Acute Coronary Syndromes
Interventions:   Drug: CER-001;   Drug: Placebo
Sponsors:   Cerenis Therapeutics, SA;   South Australian Health and Medical Research Institute
Recruiting - verified May 2016

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Standard of care drugs
Sponsor:   Bayer
Recruiting - verified May 2016

The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome

Conditions:   Depression;   Acute Coronary Syndrome
Interventions:   Drug: Melatonin (N-acetyl-5-methoxytryptamine);   Drug: Placebo
Sponsors:   Roskilde County Hospital;   Psychiatric Research Unit, Region Zealand, Denmark;   University of Copenhagen;   Pharma Nord
Recruiting - verified May 2016

Effect of Ticagrelor Versus Clopidogrel on Endothelial Dysfunction and Vascular Inflammation

Conditions:   Endothelial Dysfunction;   Vascular Inflammation
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel
Sponsors:   Seoul St. Mary's Hospital;   AstraZeneca
Recruiting - verified May 2016

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified May 2016

Exploring the Mechanism of the Plaque Rupture in Acute Myocardial Infarction

Conditions:   Acute Coronary Syndrome;   Myocardial Infarction;   Plaque, Atherosclerotic;   Rupture, Spontaneous
Intervention:  
Sponsors:   Seoul National University Hospital;   HeartFlow, Inc.;   Kyoto University, Graduate School of Medicine;   Inje University;   Keimyung University Dongsan Medical Center;   Ulsan University Hospital;   Wakayama Medical University;   Aarhus University Hospital
Active, not recruiting - verified May 2016

The Role of Gut Microbiota in Hypertension

Condition:   Hypertension
Intervention:   Other: Stool Sample and Blood Sample
Sponsor:   University of Florida
Recruiting - verified May 2016

Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

Conditions:   Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Acute Biphenotypic Leukemia;   Acute Leukemia of Ambiguous Lineage;   Acute Undifferentiated Leukemia;   Adult Acute Lymphoblastic Leukemia in Remission;   Adult Acute Myeloid Leukemia in Remission;   Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Childhood Acute Lymphoblastic Leukemia in Remission;   Childhood Acute Myeloid Leukemia in Remission;   Graft Versus Host Disease;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Childhood Acute Lymphoblastic Leukemia;   Recurrent Childhood Acute Myeloid Leukemia;   Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Refractory Anemia With Excess Blasts
Interventions:   Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;   Drug: Cyclophosphamide;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Drug: Methotrexate;   Drug: Mycophenolate Mofetil;   Procedure: Peripheral Blood Stem Cell Transplantation;   Procedure: Peripheral Blood Stem Cell Transplantation;   Drug: Tacrolimus;   Drug: Thiotepa;   Radiation: Total-Body Irradiation
Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

HEART Pathway Implementation

Conditions:   Chest Pain;   Acute Coronary Syndrome;   Chest Pain Atypical Syndrome;   Chest Pain Rule Out Myocardial Infarction
Intervention:  
Sponsors:   Wake Forest Baptist Health;   Association of American Medical Colleges;   Donaghue Medical Research Foundation
Active, not recruiting - verified May 2016

Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury

Conditions:   Acute Lung Injury;   Sepsis
Interventions:   Drug: Ascorbic Acid;   Drug: Placebo: 5% Dextrose in water
Sponsors:   Virginia Commonwealth University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Antiplatelet Therapy Following Stent Implantation

Conditions:   Acute Myocardial Infarction;   Coronary Syndrome;   Angina, Unstable
Intervention:  
Sponsor:   Elpen Pharmaceutical Co. Inc.
Completed - verified May 2016

Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease

Conditions:   Kawasaki Disease;   Coronary Aneurysm
Interventions:   Drug: Doxycycline;   Drug: Standard care
Sponsor:   Hawaii Pacific Health
Recruiting - verified May 2016

Mechanisms of Vasovagal Syncope

Conditions:   Vasovagal Syncope;   Postural Tachycardia Syndrome
Interventions:   Drug: Phenylephrine;   Drug: L-Ng-monomethyl Arginine (L-NMMA)
Sponsor:   New York Medical College
Recruiting - verified May 2016

Acute Versus Subacute Angioplasty in Patients With NON-ST-Elevation Myocardial Infarction

Condition:   Myocardial Infarction
Intervention:   Procedure: Group I: Primary PCI
Sponsor:   Aarhus University Hospital Skejby
Terminated - verified May 2016

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Active, not recruiting - verified May 2016

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Conditions:   Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions:   Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
Sponsors:   New York University School of Medicine;   New York University;   Stanford University;   National Heart, Lung, and Blood Institute (NHLBI);   Albany Stratton VA Medical Center;   Cedars-Sinai Medical Center;   Columbia University;   Duke University;   East Carolina University;   Emory University;   Harvard University;   Massachusetts General Hospital;   Montreal Heart Institute;   University of British Columbia;   University of Missouri, Kansas City;   Vanderbilt University
Recruiting - verified May 2016

Allogeneic Transplant in HIV Patients (BMT CTN 0903)

Conditions:   Leukemia;   Lymphoma;   HIV
Interventions:   Drug: Fludarabine and Busulfan;   Drug: Fludarabine and Melphalan;   Drug: Busulfan and Fludarabine;   Drug: Cyclophosphamide and Total Body Irradiation
Sponsors:   Medical College of Wisconsin;   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI);   Blood and Marrow Transplant Clinical Trials Network;   National Marrow Donor Program
Active, not recruiting - verified May 2016

International Survey of Acute Coronary Syndromes in Transitional Countries

Conditions:   Acute Coronary Syndrome;   Unstable Angina Pectoris;   Myocardial Infarction;   Coronary Disease
Intervention:  
Sponsor:   University of Bologna
Recruiting - verified May 2016

The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study

Conditions:   Delirium;   Impaired Cognition;   Long Term Psychologic Disorders
Interventions:   Drug: Haloperidol;   Drug: Ziprasidone;   Drug: Placebo
Sponsor:   Vanderbilt University
Recruiting - verified May 2016

Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies

Conditions:   Accelerated Phase Chronic Myelogenous Leukemia;   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Childhood Acute Lymphoblastic Leukemia in Remission;   Childhood Acute Myeloid Leukemia in Remission;   Childhood Chronic Myelogenous Leukemia;   Childhood Myelodysplastic Syndromes;   Chronic Phase Chronic Myelogenous Leukemia;   de Novo Myelodysplastic Syndromes;   Previously Treated Myelodysplastic Syndromes;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Excess Blasts in Transformation;   Relapsing Chronic Myelogenous Leukemia;   Secondary Myelodysplastic Syndromes
Interventions:   Procedure: umbilical cord blood transplantation;   Drug: fludarabine phosphate;   Drug: cyclophosphamide;   Procedure: ex vivo-expanded cord blood progenitor cell infusion;   Radiation: total-body irradiation;   Drug: cyclosporine;   Drug: mycophenolate mofetil;   Other: laboratory biomarker analysis
Sponsors:   Fred Hutchinson Cancer Research Center;   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI)
Completed - verified May 2016

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

Conditions:   Anemia;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Previously Treated Myelodysplastic Syndrome
Interventions:   Biological: Epoetin Alfa;   Other: Laboratory Biomarker Analysis;   Drug: Lenalidomide
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified May 2016

Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601)

Condition:   Sickle Cell Disease
Intervention:   Biological: Hematopoietic Stem Cell Transplantation
Sponsors:   Medical College of Wisconsin;   National Heart, Lung, and Blood Institute (NHLBI);   Blood and Marrow Transplant Clinical Trials Network;   National Cancer Institute (NCI);   National Marrow Donor Program;   Sickle Cell Disease Clinical Research Network
Active, not recruiting - verified May 2016

Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

Conditions:   Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Essential Thrombocythemia;   Myeloproliferative Neoplasm;   Paroxysmal Nocturnal Hemoglobinuria;   Polycythemia Vera;   Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase;   Primary Myelofibrosis;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Ring Sideroblasts;   Refractory Cytopenia With Multilineage Dysplasia;   Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts
Interventions:   Drug: Cyclosporine;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Drug: Mycophenolate Mofetil;   Procedure: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation;   Procedure: Peripheral Blood Stem Cell Transplantation;   Radiation: Total-Body Irradiation
Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Conditions:   B-cell Childhood Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions:   Drug: doxorubicin hydrochloride;   Radiation: 3-dimensional conformal radiation therapy;   Drug: cytarabine;   Drug: dexamethasone;   Drug: pegaspargase;   Drug: methotrexate;   Drug: leucovorin calcium;   Drug: mercaptopurine;   Drug: cyclophosphamide;   Drug: thioguanine;   Drug: vincristine sulfate
Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
Active, not recruiting - verified May 2016

Natural History of Sickle Cell Disease and Other Hemolytic Disorders

Conditions:   Hemoglobin SC Disease;   Hematologic Diseases;   Sickle Cell Anemia;   Hemolytic Anemia
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2016