Acute Coronary Syndrome

Clinical Trial Finder

Many patients with acute coronary syndrome are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Factors Associated With Perioperative Outcomes in Non-emergency Surgery

Conditions:   Stroke;   Acute Coronary Syndrome;   Pneumonia
Intervention:   Other: stroke or myocardial infarction or pneumonia
Sponsors:   University of Nottingham;   University of Wisconsin, Madison
Completed - verified May 2015

The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome

Conditions:   Depression;   Acute Coronary Syndrome
Interventions:   Drug: Melatonin (N-acetyl-5-methoxytryptamine);   Drug: Placebo
Sponsors:   Roskilde County Hospital;   Psychiatric Research Unit, Region Zealand, Denmark;   University of Copenhagen;   Pharma Nord
Not yet recruiting - verified May 2015

Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome

Conditions:   Cardiac Death;   Hemorrhage;   Cerebrovascular Accident;   Myocardial Infarction
Interventions:   Device: BES (biodegradable polymer biolimus-eluting stent);   Drug: Prasugel;   Drug: Clopidogrel
Sponsor:   Chonnam National University Hospital
Recruiting - verified May 2015

Natural History of Atherosclerosis in Real-World Patients Underwent Computed Tomography Angiography

Conditions:   Coronary Atherosclerosis;   Coronary Artery Disease;   Radiocontrast-induced Thyroid Dysfunction;   Contrast-induced Nephropathy
Interventions:   Radiation: Coronary computed tomography angiography;   Radiation: Quantitative coronary angiography
Sponsors:   Ural State Medical Academy;   Ural Institute of Cardiology;   De Haar Research Foundation
Enrolling by invitation - verified May 2015

Prospective Registry of Acute Heart Failure

Condition:   Acute Heart Failure
Intervention:   Procedure: blood sample
Sponsor:   Sebastian Carballo
Recruiting - verified May 2015

COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial

Condition:   ST Elevation Acute Myocardial Infarction
Interventions:   Drug: Exenatide;   Other: Remote Ischemic Conditioning (RIC)
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Not yet recruiting - verified March 2015

The Impact of Metabolic Syndrome on Patients Undergoing Elective Laparotomy

Conditions:   Metabolic Syndrome;   Anesthesia;   Perioperative Outcome;   Complications
Intervention:   Procedure: Elective abdominal surgery
Sponsor:   University of Ioannina
Completed - verified May 2015

Fungemia in Hematologic Malignancies

Conditions:   Acute Leukemia;   Chronic Leukemia;   Multiple Myeloma;   Lymphoma
Sponsor:   Sorveglianza Epidemiologica Infezioni Fungine Emopatie Maligne
Recruiting - verified May 2015

The Use of Texting Messaging to Improve the Hospital-to-community Transition Period in Cardiovascular Disease Patients

Conditions:   Cardiovascular Disease;   Acute Coronary Syndrome
Intervention:   Behavioral: Txt2Prevent
Sponsors:   Simon Fraser University;   Providence Health & Services;   University of British Columbia;   McMaster University;   Canadian Institutes of Health Research  (CIHR)
Not yet recruiting - verified May 2015

Clinical Trial to Evaluate the Use of an Adsorption Membrane (OXIRIS®) During Cardiopulmonary Bypass Surgery

Conditions:   Cardiac Surgical Procedures;   Cardiopulmonary Bypass
Intervention:   Device: OXIRIS®
Sponsors:   Hospital Universitari de Bellvitge;   Gambro Renal Products, Inc.
Recruiting - verified May 2015

A Randomized Placebo-controlled Phase 2 Study of Decitabine With or Without Eltrombopag in AML Patients

Condition:   Acute Myeloid Leukemia
Interventions:   Drug: Eltrombopag;   Drug: Placebo
Sponsors:   Technische Universität Dresden;   GlaxoSmithKline
Not yet recruiting - verified May 2015

Palliative Care for Patients With Advanced Heart Disease

Conditions:   Acute Coronary Syndrome;   Congestive Cardiac Failure;   Palliative Care
Intervention:   Other: Palliative Care Intervention
Sponsor:   University of Edinburgh
Recruiting - verified May 2015

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid;   Drug: Rivaroxaban;   Drug: Clopidogrel;   Drug: Ticagrelor
Sponsors:   Janssen Research & Development, LLC;   Bayer;   Duke Clinical Research Institute;   Harvard Medical School
Recruiting - verified May 2015

RuSsian RegisTry of Acute CoronaRy SyndromE TreAtMent and Approach in Dual Antiplatelet Therapy

Condition:   Acute Coronary Syndrome
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Real Life Long-term Adherence to Ticagrelor After PCI for Acute Coronary Syndromes

Condition:   Acute Coronary Syndrome (ACS)
Intervention:   Drug: Ticagrelor
Sponsor:   IHF GmbH - Institut für Herzinfarktforschung
Active, not recruiting - verified May 2015

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

Condition:   Acute Coronary Syndromes
Intervention:   Other: Non-Interventional Study
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Rapid Assessment of Potential Ischaemic Heart Disease With CTCA

Condition:   Acute Coronary Syndrome
Intervention:   Radiation: CT Coronary Angiogram
Sponsors:   University of Edinburgh;   NHS Lothian
Recruiting - verified May 2015

Prediction of Recurrent Events With 18F-Fluoride

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Sponsors:   University of Edinburgh;   NHS Lothian;   Oxford University Hospitals NHS Trust;   Central Manchester University Hospitals NHS Foundation Trust;   NHS Grampian;   Wellcome Trust
Not yet recruiting - verified May 2015

Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

Conditions:   Chemotherapeutic Agent Toxicity;   Neuropathy;   Neurotoxicity Syndrome;   Pain;   Stage IIIA Fallopian Tube Cancer;   Stage IIIA Ovarian Cancer;   Stage IIIA Primary Peritoneal Cancer;   Stage IIIB Fallopian Tube Cancer;   Stage IIIB Ovarian Cancer;   Stage IIIB Primary Peritoneal Cancer;   Stage IIIC Fallopian Tube Cancer;   Stage IIIC Ovarian Cancer;   Stage IIIC Primary Peritoneal Cancer;   Stage IV Fallopian Tube Cancer;   Stage IV Ovarian Cancer;   Stage IV Primary Peritoneal Cancer
Interventions:   Drug: Carboplatin;   Drug: Glutathione;   Other: Laboratory Biomarker Analysis;   Drug: Paclitaxel;   Other: Placebo;   Other: Quality-of-Life Assessment
Sponsor:   National Cancer Institute (NCI)
Completed - verified May 2013

MicroRNA Diagnostics in Subarachnoid Hemorrhage 2

Conditions:   Subarachnoid Hemorrhage;   Delayed Cerebral Ischemia;   Acute Lung Injury;   Cardiac Dysfunction;   Systemic Inflammatory Response Syndrome
Sponsor:   Rigshospitalet, Denmark
Completed - verified May 2015

Origin of Premature Atrial Beats Induced by Simulated Obstructive Sleep Apnea

Conditions:   Atrial Fibrillation;   Sleep Apnea, Obstructive;   Atrial Premature Complexes
Intervention:   Procedure: Standard pulmonary vein isolation
Sponsor:   University of Zurich
Recruiting - verified May 2015

APRV/BIPAP With Spontaneous Breathing on Lung Protection

Conditions:   Respiratory Insufficiency;   Ventilator-Induced Lung Injury
Intervention:   Other: Pressure targeted modes
Sponsors:   St. Michael's Hospital, Toronto;   University of Toronto
Recruiting - verified May 2015

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Condition:   Acute Coronary Syndrome
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Treosulfan and Fludarabine Phosphate With or Without Total Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Conditions:   Acute Myeloid Leukemia in Remission;   Chronic Myelomonocytic Leukemia;   Minimal Residual Disease;   Myelodysplastic Syndrome;   Myelodysplastic/Myeloproliferative Neoplasm;   Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable
Interventions:   Procedure: Allogeneic Bone Marrow Transplantation;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Procedure: Peripheral Blood Stem Cell Transplantation;   Radiation: Total-Body Irradiation;   Drug: Treosulfan
Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2015

Low-Dose Coronary Computed Tomographic Angiography for Early Triage of Acute Chest Pain

Condition:   Chest Pain
Interventions:   Other: Low-dose Cardiac CT protocol;   Other: Conventional cardiac CT protocol
Sponsor:   Seoul National University Hospital
Recruiting - verified May 2014

RITHM - Resonance Imaging Trial for Heart Biomarkers in Adolescent/Young (AYA) Cancer Survivors

Conditions:   if Aortic Stiffness;   Myocardial Wall Strain
Sponsor:   Comprehensive Cancer Center of Wake Forest University
Active, not recruiting - verified May 2015

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab SAR236553 (REGN727)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Other: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified May 2015

Donor Umbilical Cord Blood Transplant With or Without Ex-Vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes

Conditions:   Acute Biphenotypic Leukemia;   Acute Lymphoblastic Leukemia in Remission;   Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome;   Acute Myeloid Leukemia in Remission;   Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   de Novo Myelodysplastic Syndrome;   Mixed Phenotype Acute Leukemia;   Pancytopenia;   Previously Treated Myelodysplastic Syndrome;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Excess Blasts in Transformation;   Secondary Acute Myeloid Leukemia
Interventions:   Drug: Cyclophosphamide;   Drug: Cyclosporine;   Procedure: Double-Unit Umbilical Cord Blood Transplantation;   Procedure: Ex Vivo-Expanded Cord Blood Progenitor Cell Infusion;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Drug: Mycophenolate Mofetil;   Radiation: Total-Body Irradiation;   Procedure: Umbilical Cord Blood Transplantation
Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2015

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Sponsor:   AstraZeneca
Recruiting - verified May 2015

Meta-analyses of the Effect of Dietary Pulses on Acute Postprandial Metabolic Control

Conditions:   Diabetes;   Prediabetes;   Dysglycemia;   Overweight;   Obesity;   Metabolic Syndrome;   Cardiovascular Disease
Intervention:   Other: Dietary pulses
Sponsors:   John Sievenpiper;   Pulse Canada;   Canada Research Chairs Endowment of the Federal Government of Canada;   Canadian Institutes of Health Research  (CIHR)
Active, not recruiting - verified May 2015

Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy

Conditions:   Apical Ballooning Syndrome;   Nervous System Diseases, Sympathetic
Interventions:   Drug: Placebo;   Drug: alpha-lipoic acid;   Drug: L-acetyl carnitine
Sponsor:   Second University of Naples
Active, not recruiting - verified May 2015

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Conditions:   Adult Myelodysplastic Syndrome;   Chronic Myelomonocytic Leukemia;   Chronic Myelomonocytic Leukemia-1;   Chronic Myelomonocytic Leukemia-2;   Previously Treated Myelodysplastic Syndrome;   Refractory Anemia With Excess Blasts
Interventions:   Drug: Azacitidine;   Drug: Lenalidomide;   Drug: Vorinostat
Sponsor:   National Cancer Institute (NCI)
Active, not recruiting - verified March 2015

Allopurinol in Acute Coronary Syndrome

Condition:   Chronic Stable Angina
Interventions:   Drug: Allopurinol;   Drug: Allopurinol;   Drug: Placebo
Sponsors:   Stephen McSwiggan;   British Heart Foundation
Terminated - verified May 2015

International Survey of Acute Coronary Syndromes in Transitional Countries

Conditions:   Acute Coronary Syndrome;   Unstable Angina Pectoris;   Myocardial Infarction;   Coronary Disease
Sponsor:   University of Bologna
Recruiting - verified May 2015

Registry of Acute Coronary Syndromes in the Lazio Region of Italy

Condition:   Acute Coronary Syndromes
Sponsors:   San Filippo Neri General Hospital;   Associazione Nazionale Medici Cardiologi Ospedalieri
Recruiting - verified May 2015

INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery

Condition:   Systemic Inflammatory Response Syndrome
Intervention:   Procedure: cardiac surgery with CPB use
Sponsors:   Medical University of Gdansk;   Ministry of Science and Higher Education, Poland
Completed - verified May 2015

Cardiovascular Magnetic Resonance for the Occluded Infarct-Related Artery Treatment

Conditions:   Cardiovascular Diseases;   Heart Diseases;   Myocardial Infarction;   Heart Failure
Interventions:   Drug: Beta adrenergic blockers;   Drug: Platelet inhibitors;   Drug: Statins;   Drug: ACE inhibitors and/or ARB and/or AA;   Procedure: PCI with stenting
Sponsor:   Institute of Cardiology, Warsaw, Poland
Terminated - verified May 2015

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

Conditions:   Anemia;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndrome;   Previously Treated Myelodysplastic Syndrome
Interventions:   Biological: Epoetin Alfa;   Other: Laboratory Biomarker Analysis;   Drug: Lenalidomide
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified April 2015

Improving Medication Adherence in Post-ACS Patients

Conditions:   Medication Adherence;   Acute Coronary Syndrome
Intervention:   Behavioral: PST therapy
Sponsors:   Columbia University;   National Heart, Lung, and Blood Institute (NHLBI)
Terminated - verified May 2015

Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402)

Conditions:   Leukemia, Myelocytic, Acute;   Leukemia, Lymphocytic, Acute;   Leukemia, Myeloid, Chronic;   Myelodysplastic Syndromes
Interventions:   Drug: Tacrolimus;   Drug: Methotrexate;   Drug: Sirolimus
Sponsors:   Medical College of Wisconsin;   National Heart, Lung, and Blood Institute (NHLBI);   Blood and Marrow Transplant Clinical Trials Network;   National Cancer Institute (NCI)
Active, not recruiting - verified November 2014

Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

Conditions:   Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative;   Childhood Myelodysplastic Syndromes;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndromes;   Essential Thrombocythemia;   Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable;   Paroxysmal Nocturnal Hemoglobinuria;   Philadelphia Chromosome Negative Chronic Myelogenous Leukemia;   Polycythemia Vera;   Primary Myelofibrosis;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Ringed Sideroblasts;   Refractory Cytopenia With Multilineage Dysplasia;   Secondary Myelodysplastic Syndromes;   Secondary Myelofibrosis
Interventions:   Radiation: total-body irradiation;   Drug: fludarabine phosphate;   Procedure: peripheral blood stem cell transplantation;   Drug: cyclosporine;   Drug: mycophenolate mofetil;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation
Sponsors:   Fred Hutchinson Cancer Research Center;   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI)
Recruiting - verified May 2015

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