acetaminophen and dextromethorphan

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acetaminophen and dextromethorphan

Pronunciation:a SEET a MIN oh fen and DEX troe me THOR fan
Brand:Children's Triacting, Triaminic Cough & Sore Throat, Triaminic Cough & Sore Throat Softchews, Tylenol Cough and Sore Throat Daytime

What is the most important information I should know about acetaminophen and dextromethorphan?

emtDo not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take acetaminophen.
donotDo not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.
noalcoholAvoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.
nochildDo not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
donotDo not use a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
emtAsk a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

What is acetaminophen and dextromethorphan?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

The combination of acetaminophen and dextromethorphan is used to treat cough and pain or fever caused by the common cold or flu.

smokingDextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen and dextromethorphan may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking acetaminophen and dextromethorphan?

donotDo not take this medication if you are allergic to acetaminophen or dextromethorphan.
emtDo not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take acetaminophen.
donotDo not use a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have liver disease or a history of alcoholism.

nopregIt is not known whether acetaminophen and dextromethorphan will harm an unborn baby. Do not use cold or cough medicine without medical advice if you are pregnant.
nobrfeedIt is not known whether acetaminophen and dextromethorphan will harm an unborn baby. Do not use cold or cough medicine without medical advice if you are pregnant.

Artificially sweetened liquid cough or cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

How should I take acetaminophen and dextromethorphan?

donotUse exactly as directed on the label, or as prescribed by your doctor. Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

nochildDo not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

waterDrink extra fluids while you are taking this medication.
donotTalk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.
emtIf you need surgery, tell the surgeon ahead of time that you are using acetaminophen and dextromethorphan. You may need to stop using the medicine for a short time.
rtStore at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Since cough or cold medicine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

emtSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include dizziness, drowsiness, feeling restless or nervous, diarrhea, loss of appetite, seizure (convulsions), or coma.

What should I avoid while taking acetaminophen and dextromethorphan?

dizzyThis medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
donotAsk a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.
noalcoholAvoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with cough medicine can increase your risk of unpleasant side effects.

What are the possible side effects of acetaminophen and dextromethorphan?

emtGet emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
donotStop using this medication and call your doctor at once if you have a serious side effect such as:
  • severe dizziness, anxiety, restless feeling, or nervousness;
  • confusion, hallucinations;
  • slow, shallow breathing;
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • upset stomach.
  • mild loss of appetite; or

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect acetaminophen and dextromethorphan?

Tell your doctor about all other medicines you use, especially:

  • celecoxib (Celebrex);
  • cinacalcet (Sensipar);
  • darifenacin (Enablex);
  • imatinib (Gleevec);
  • isoniazid;
  • quinidine (Quin-G);
  • ranolazine (Ranexa);
  • ritonavir (Norvir, Kaletra);
  • sibutramine (Meridia);
  • terbinafine (Lamisil);
  • zidovudine (Retrovir, AZT);
  • gout medication such as probenecid (Benemid);
  • medicines to treat high blood pressure;
  • seizure medication such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton); or
  • an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), bupropion (Wellbutrin, Zyban, Aplenzin), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), sertraline (Zoloft), and others.

This list is not complete and other drugs may interact with acetaminophen and dextromethorphan. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about acetaminophen and dextromethorphan.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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