diazepam rectal

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diazepam rectal

Pronunciation:dye AZ e pam
Brand:Diastat AcuDial, Diastat Pediatric

What is the most important information I should know about diazepam rectal?

donotYou should not receive this medication if you are allergic to diazepam (Valium), or if you have untreated or uncontrolled narrow-angle glaucoma.

Before using diazepam rectal, tell your doctor if you have glaucoma, liver or kidney disease, asthma, pneumonia, other breathing problems, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol. Also tell your doctor if you are allergic to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), lorazepam (Ativan), or oxazepam (Serax).

emtThis medication is usually given by a caregiver to the person who is having a seizure. Not all types of seizures can be treated with diazepam rectal. If you are the caregiver, do not give this medication unless you know how to recognize the symptoms of a seizure episode that should be treated with diazepam rectal.
emtDiazepam rectal may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant while using diazepam rectal for seizures. Do not start or stop using any of your seizure medications during pregnancy without your doctor's advice.

There are many other drugs that can interact with diazepam rectal. Tell your doctor about all medications you use.

habitDiazepam may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

What is diazepam rectal?

Diazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Diazepam affects chemicals in the brain that may become unbalanced and cause seizure.

Diazepam rectal is used to treat occasionally increased seizures (cluster seizures) in people with epilepsy who also routinely take other anti-convulsants. Diazepam rectal is not for long-term daily use to prevent seizures.

Diazepam rectal may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using diazepam rectal?

donotYou should not receive this medication if you are allergic to diazepam (Valium), or if you have untreated or uncontrolled narrow-angle glaucoma.

To make sure you can safely use diazepam rectal, tell your doctor if you have any of these other conditions:

  • glaucoma;
  • asthma, pneumonia, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
  • liver or kidney disease;
  • a history of depression or suicidal thoughts or behavior;
  • a history of drug or alcohol addiction; or
  • if you are allergic to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), lorazepam (Ativan), or oxazepam (Serax).
nopregFDA pregnancy category D. Diazepam may cause harm to an unborn baby. Do not start using diazepam rectal without telling your doctor if you are pregnant or planning to become pregnant. Use effective birth control while you are using diazepam rectal.
emtAlthough diazepam rectal may harm an unborn baby, having a seizure during pregnancy could harm both mother and baby. If you become pregnant while using diazepam rectal, do not stop using the medicine without your doctor's advice.

Seizure control is very important during pregnancy. The benefit of preventing seizures may outweigh any risks posed by using diazepam rectal. Follow your doctor's instructions about taking any of your seizure medications while you are pregnant.

nobrfeedDiazepam may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The sedative effects of diazepam rectal may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are using diazepam rectal.

nochildDo not give this medication to a child younger than 6 months old.

How should I use diazepam rectal?

Use this medication exactly as it was prescribed. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on the prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

This medication is usually given by a caregiver to the person who is having a seizure. If you are the caregiver, make sure you know and understand all instructions for giving diazepam rectal.

emtNot all types of seizures can be treated with diazepam rectal. If you are the caregiver, do not give this medication unless you know how to recognize the symptoms of a seizure episode that should be treated with diazepam rectal.

After given diazepam rectal to another person, stay with the person for at least 4 hours and watch for changes in his or her breathing, and any side effects from the medicine.

emtGet emergency medical help if:
  • the seizure has not stopped within 15 minutes after giving diazepam rectal;
  • the seizure seems to be different from the person's usual seizures;
  • the seizures seems to be closer together or more severe than the person's usual seizures; or
  • the person has breathing problems, pale or blue-colored skin, or any other serious or unusual problems.

Diazepam rectal is used in combination with other seizure medications. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Diazepam rectal is not for long-term daily use to prevent seizures. Using diazepam rectal daily over long periods can actually make your seizures more frequent or more severe. You may also have withdrawal symptoms when you stop using diazepam rectal.

habitDiazepam may be habit forming and should be used only by the person it was prescribed for. Never share this medication with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
emtDo not use this medication for longer than 5 days in a row without a doctor's advice. Contact your doctor if this medicine seems to stop working as well in treating your symptoms.
rtStore at room temperature away from moisture, heat, and light.

After giving a dose of diazepam rectal, empty any leftover medicine from the syringe into a toilet and flush, or into a sink and rinse down the drain. Throw the empty syringe away where children and pets cannot get to it. Do not reuse a diazepam rectal syringe.

What happens if I miss a dose?

Since diazepam rectal is used on an as needed basis, you are not likely to miss a dose.

What happens if I overdose?

emtSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.

What should I avoid while using diazepam rectal?

noalcoholDo not drink alcohol while using diazepam rectal. This medication can increase the effects of alcohol, which could be dangerous.
dizzyDiazepam may impair your thinking or reactions. Do not drive, operate machinery, or perform other hazardous activities until you are alert and awake and you no longer feel drowsy from this medicine.

What are the possible side effects of diazepam rectal?

emtGet emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
donotCall your doctor at once if the person receiving this medication has a serious side effect such as:
  • worsening seizures, or seizures that seem different from the patient's other seizures;
  • pale or discolored skin;
  • confusion, hallucinations, unusual thoughts or behavior, unusual risk-taking behavior, decreased inhibitions, no fear of danger;
  • hyperactivity, agitation, hostility, depressed mood, thoughts of suicide or hurting yourself;
  • feeling like you might pass out; or
  • pain or burning when you urinate.

Less serious side effects may include:

  • headache, blurred vision, dizziness, drowsiness, tiredness;
  • sleep problems (insomnia);
  • slurred speech, loss of balance or coordination; or
  • nausea, vomiting, stomach pain, diarrhea.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect diazepam rectal?

dizzyCold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for depression or anxiety can add to sleepiness caused by diazepam rectal. Tell your doctor if you regularly use any of these medicines.

Tell your doctor about all other medicines you use, especially:

  • cyclosporine (Gengraf, Neoral, Sandimmune);
  • dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
  • theophylline (Elixophyllin, Theo-24, Theochron, Uniphyl);
  • valproic acid (Depakene, Stavzor);
  • an antibiotic or antifungal medication;
  • an antidepressant;
  • a barbiturate such as phenobarbital (Solfoton);
  • a blood thinner such as warfarin (Coumadin, Jantoven);
  • heart or blood pressure medication;
  • HIV/AIDS medication;
  • an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);
  • phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Permitil, Prolixin), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Pentazine, Phenergan, Anergan, Antinaus), thioridazine (Mellaril), or trifluoperazine (Stelazine);
  • seizure medication; or
  • stomach acid reducers such as cimetidine (Tagamet), lansoprazole (Prevacid), omeprazole (Prilosec).

This list is not complete and other drugs may interact with diazepam rectal. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about diazepam rectal.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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