Description

Hydralazine is a medication which directly acts on muscle surrounding blood vessels to cause relaxation. This helps to lower blood pressure and reduce workload on the heart. As a result of this, hydralazine is therapeutically used in hypertension and in chronic or congestive heart failure (in combination with a nitrate). Since hydralazine is short acting, it must be dosed frequently throughout the day which will often make the medication less preferred for initial therapy compared to other options. It does, however, maintain a strong role in high blood pressure unresponsive to other medications and in the treatment of heart failure, particularly in combination with a nitrate in African Americans.

When might my doctor prescribe this medication?

• High blood pressure (or hypertension)
• Chronic or congestive heart failure

I should NOT take this medication if:

• I have had severe allergic reactions to hydralazine in the past

Adverse Effects (common)

• Dizziness
• Leg swelling (or edema)
• Fast heart rate
• Chest pain

Adverse Effects (rare, but serious)

• Lupus like reaction

Common Adult Doses and Forms

Hydralazine (Apresoline): 25 mg to 100 mg three times daily       

Dosage Forms:
Hydralazine (Apresoline): 10 mg, 25 mg, 50 mg, 100 mg

How should I take this medication?