Medication Basics
Generic Name: Gemfibrozil
Brand Name: Lopid
Medication Class: Cholesterol Medication – Fibrate
Description
The fibrates help to lower triglyceride levels, which have been shown to contribute to cardiovascular disease when elevated. Patients with metabolic syndrome or diabetes may be at particular risk for high triglycerides. Fibrates also help to lower bad cholesterol (LDL), but are not as effective as statin drugs for this. Fenofibrate may be preferred over gemfibrozil due to fewer gastrointestinal side effects.
When Might My Doctor Prescribe This Medication?
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Elevated triglycerides (or hypertriglyceridemia)
I should NOT take this medication if:
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I have had allergic reactions to gemfibrozil in the past
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I have severe liver disease
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I have severe kidney disease
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I have gallbladder disease that has not been treated
Adverse Effects (common)
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Gastrointestinal pain or upset stomach
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Diarrhea or constipation
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Nausea and vomiting
Adverse Effects (rare, but serious)
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Liver failure
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Gallstones (or cholelethiasis)
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Kidney failure from muscle breakdown (or rhabdomyolysis)
Common Adult Doses and Forms
Gemfibrozil (Lopid): 600 mg twice daily
Dosage Forms:
Gemfibrozil (Lopid) (tablet): 600 mg
How should I take this medication?
Gemfibrozil should be taken 30 minutes before meals.
Please note that the content on CardioSmart is a summary of the most generally pertinent information about this drug but does not cover every side effect or precaution. However, everyone is unique, and the extent to which the information applies specifically to you should be a key point of discussion between you and your cardiologist or health care provider. The ultimate judgment regarding your care must be made by you and your healthcare provider together, in light of circumstances specific to you as a patient.
