Description

The fibrates help to lower triglyceride levels, which have been shown to contribute to cardiovascular disease when elevated. Patients with metabolic syndrome or diabetes may be at particular risk for high triglycerides.  Fibrates also help to lower bad cholesterol (LDL), but are not as effective as statin drugs for this. Fenofibrate may be preferred over gemfibrozil due to fewer gastrointestinal side effects.

When might my doctor prescribe this medication?

• Elevated triglycerides (or hypertriglyceridemia)

I should NOT take this medication if:

• I have had allergic reactions to fenofibrate in the past
• I have severe liver disease
• I have severe kidney disease
• I have gallbladder disease that has not been treated

Adverse Effects (common):

•  Headache
• Gastrointestinal pain or upset stomach
• Diarrhea or constipation

Adverse Effects (rare, but serious):

• Liver failure
• Gallstones (or cholelethiasis)
• Kidney failure from muscle breakdown (or rhabdomyolysis)

Common Adult Doses and Forms

Fenofibrate (Tricor): 48 to 145 mg once daily
Fenofibrate (Lofibra - micronized): 67 to 200 mg once daily
Fenofibrate (Lofibra): 54 to 160 mg once daily

Dosage Forms:
Fenofibrate (Tricor) (tablet): 48 mg, 145 mg
Fenofibrate (Lofibra – micronized) (capsule): 67 mg, 134 mg, 200 mg
Fenofibrate (Lofibra) (tablet): 54 mg, 160 mg

How should I take this medication?

Tricor may be taken with or without meals. Lofibra (both formulations) should be taken with food.