Clonidine

Medication Basics

Generic Name: Clonidine

Brand Name: Catapres, Catapres-TTS
Medication Class: Central Alpha Stimulator

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Description

Clonidine is a medication that stimulates a receptor in the brain which causes fewer chemicals to be released that can increase vascular constriction. It therefore is able to lower blood pressure. Although it is an extremely effective medication, side effects and the need for frequent dosing throughout the day limit its use to cases where blood pressure is unable to be controlled by simpler medications.

When might my doctor prescribe this medication?

  • High blood pressure (or hypertension)

I should NOT take this medication if:

  • I have had a severe allergic reaction to clonidine in the past

Adverse Effects (common)

  • Drowsiness
  • Dizziness
  • Skin reactions (patch only)
  • Dry mouth
  • Fatigue
  • Depression

Common Adult Doses and Forms

Clonidine (Catapres): 0.1 mg to 0.3 mg three times daily
Clonidine patch (Catapres-TTS): 0.1 mg/day to 0.3 mg/day changed once weekly

Dosage Forms:
Clonidine (Catapres) (tablet): 0.1 mg, 0.2 mg, 0.3 mg
Clonidine patch (Catapres-TTS): TTS-1 (0.1 mg/day), TTS-2 (0.2 mg/day), TTS-3 (0.3 mg/day)

How should I take this medication?

Clonidine can be taken with or without meals. Clonidine pills should NOT be discontinued suddenly, as blood pressure can increase abruptly to dangerous levels. It should be tapered off gradually over several days. When changing from pills over to the patch, the pills must be tapered off until the patch builds up a high enough level of drug in the skin. Patches should not be cut or divided in any way.

Please note that the content on CardioSmart is a summary of the most generally pertinent information about this drug but does not cover every side effect or precaution. However, everyone is unique, and the extent to which the information applies specifically to you should be a key point of discussion between you and your cardiologist or health care provider. The ultimate judgment regarding your care must be made by you and your healthcare provider together, in light of circumstances specific to you as a patient.